Data for Biomarkers of NAFLD progression: a lipidomics approach to an epidemic. Part 3:Urine (Study ST000917)
(Analysis AN001501)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 |
|---|---|---|---|---|
| C14 Cer | 1.4327 | 0.7752 | 0.6786 | 1.3093 |
| C14DH Cer | 0.9652 | 1.0693 | 0.8492 | 1.2296 |
| C14DH HexCer | 1.0390 | 0.9040 | 1.0970 | 0.8902 |
| C14DH Sphingomyelin | 1.0919 | 0.7463 | 0.8115 | 1.5080 |
| C14 GalCer | 2.7493 | 0.5186 | 0.3962 | 0.5171 |
| C14 GlcCer | 3.0133 | 0.2686 | 0.2803 | 0.7189 |
| C14 HexCer | 2.9854 | 0.3005 | 0.2957 | 0.6889 |
| C14 Sphingomyelin | 1.1580 | 0.8761 | 0.7708 | 1.3570 |
| C16 1-deoxyCer | 0.8536 | 0.6967 | 1.0408 | 1.4392 |
| C16 Cer | 0.5958 | 0.4113 | 0.9047 | 2.3017 |
| C16DH 1-deoxyCer | 0.9098 | 0.8226 | 1.0193 | 1.2703 |
| C16DH Cer | 0.4231 | 0.4354 | 0.7162 | 2.8106 |
| C16DH HexCer | 0.8917 | 0.7144 | 0.9831 | 1.4765 |
| C16DH Sphingomyelin | 0.9691 | 0.6969 | 0.8559 | 1.6293 |
| C16 GalCer | 0.7290 | 0.5005 | 0.3669 | 3.0876 |
| C16 GlcCer | 1.4940 | 0.5880 | 0.8816 | 1.0883 |
| C16 HexCer | 1.3895 | 0.5735 | 0.8107 | 1.3525 |
| C16 Sphingomyelin | 1.0334 | 0.8870 | 0.8507 | 1.3503 |
| C18:1 Cer | 1.2454 | 0.1351 | 0.1782 | 3.1282 |
| C18 1-deoxyCer | 0.8600 | 0.8431 | 0.9499 | 1.4284 |
| C18:1DH Cer | 0.5651 | 0.7841 | 0.6529 | 2.3655 |
| C18:1DH HexCer | 0.9165 | 0.8987 | 1.1216 | 0.9970 |
| C18:1 GalCer | 2.9656 | 0.2964 | 0.2202 | 0.6790 |
| C18:1 GlcCer | 3.4731 | 0.1411 | 0.1045 | 0.5781 |
| C18:1 HexCer | 3.4639 | 0.1631 | 0.1188 | 0.5917 |
| C18:1 Sphingomyelin | 1.0818 | 1.0078 | 0.8121 | 1.2266 |
| C18 Cer | 0.6322 | 0.2625 | 0.4617 | 3.2069 |
| C18DH 1-deoxyCer | 0.7621 | 0.9252 | 1.0198 | 1.3285 |
| C18DH Cer | 0.3900 | 0.5276 | 0.5800 | 2.9868 |
| C18DH HexCer | 0.6613 | 0.7338 | 1.2726 | 1.2149 |
| C18DH Sphingomyelin | 1.1554 | 0.7463 | 0.8208 | 1.4171 |
| C18 GalCer | 0.9475 | 1.1823 | 0.9003 | 1.0340 |
| C18 GlcCer | 0.8315 | 0.5769 | 0.6587 | 2.2734 |
| C18 HexCer | 0.8442 | 0.6417 | 0.6861 | 2.1377 |
| C18 Sphingomyelin | 1.1578 | 0.9986 | 0.8013 | 1.1666 |
| C20 1-deoxyCer | 1.0532 | 0.9184 | 1.0386 | 0.9604 |
| C20 Cer | 1.0895 | 0.5851 | 0.7799 | 1.7469 |
| C20DH 1-deoxyCer | 0.7173 | 1.0865 | 1.0707 | 1.1112 |
| C20DH Cer | 0.7105 | 0.6874 | 0.8809 | 1.9003 |
| C20DH HexCer | 0.8293 | 0.9565 | 1.2064 | 0.8853 |
| C20DH Sphingomyelin | 1.0538 | 0.8491 | 0.8746 | 1.3266 |
| C20 GalCer | 0.7085 | 1.2308 | 1.0650 | 0.9684 |
| C20 GlcCer | 1.7582 | 0.8427 | 0.7227 | 0.7732 |
| C20 HexCer | 1.5969 | 0.9051 | 0.7774 | 0.7967 |
| C20 Sphingomyelin | 1.1701 | 0.9605 | 0.8312 | 1.1419 |
| C22 1-deoxyCer | 1.0840 | 1.0221 | 0.8802 | 1.0879 |
| C22 Cer | 0.9267 | 0.4513 | 0.6810 | 2.2625 |
| C22DH 1-deoxyCer | 0.7598 | 0.9447 | 1.1195 | 1.1335 |
| C22DH Cer | 0.6682 | 0.6388 | 0.8105 | 2.1285 |
| C22DH HexCer | 0.8094 | 0.9014 | 1.2106 | 0.9543 |
| C22DH Sphingomyelin | 0.9915 | 0.8582 | 0.9010 | 1.3431 |
| C22 GalCer | 0.7280 | 1.2446 | 1.0547 | 0.9656 |
| C22 GlcCer | 1.4569 | 0.9219 | 0.8759 | 0.7494 |
| C22 HexCer | 1.3506 | 0.9718 | 0.8989 | 0.7830 |
| C22 Sphingomyelin | 1.1191 | 0.9365 | 0.8428 | 1.2083 |
| C24:1 1-deoxyCer | 1.3680 | 0.6587 | 0.8573 | 1.1803 |
| C24:1 Cer | 1.1184 | 0.3229 | 0.7615 | 2.0385 |
| C24 1-deoxyCer | 1.1509 | 0.9186 | 0.9050 | 1.0812 |
| C24:1DH 1-deoxyCer | 0.7387 | 0.7660 | 1.1320 | 1.3360 |
| C24:1DH Cer | 0.7495 | 0.6377 | 0.7110 | 2.2096 |
| C24:1DH HexCer | 1.5817 | 0.8192 | 0.8315 | 0.8728 |
| C24:1 GalCer | 1.0864 | 1.1436 | 0.8103 | 1.0725 |
| C24:1 GlcCer | 1.9632 | 0.7211 | 0.5918 | 0.8989 |
| C24:1 HexCer | 1.8571 | 0.7720 | 0.6183 | 0.9201 |
| C24:1 Sphingomyelin | 1.5282 | 0.7597 | 0.6995 | 1.1774 |
| C24 Cer | 0.7080 | 0.4323 | 0.8352 | 2.2688 |
| C24DH 1-deoxyCer | 0.7445 | 1.0636 | 1.0856 | 1.0785 |
| C24DH Cer | 0.5380 | 0.5834 | 0.8593 | 2.2576 |
| C24DH HexCer | 0.8458 | 0.9162 | 1.1039 | 1.0869 |
| C24DH Sphingomyelin | 0.9784 | 0.8100 | 0.8917 | 1.4288 |
| C24 GalCer | 0.7443 | 1.3722 | 1.0407 | 0.8154 |
| C24 GlcCer | 1.6700 | 0.7747 | 0.8477 | 0.7322 |
| C24 HexCer | 1.5889 | 0.8292 | 0.8627 | 0.7402 |
| C24 Sphingomyelin | 1.1524 | 0.8721 | 0.8275 | 1.2680 |
| C26:1 1-deoxyCer | 1.0052 | 1.0418 | 1.0178 | 0.9224 |
| C26:1 Cer | 0.9125 | 0.3025 | 1.1291 | 1.6547 |
| C26 1-deoxyCer | 0.9214 | 0.8362 | 1.1407 | 1.0267 |
| C26:1DH 1-deoxyCer | 1.0491 | 0.9338 | 0.9987 | 1.0057 |
| C26:1DH Cer | 0.5399 | 0.5899 | 1.3884 | 1.3141 |
| C26:1DH HexCer | 0.8605 | 1.0149 | 1.0748 | 1.0155 |
| C26:1 GalCer | 1.3000 | 0.9018 | 0.8641 | 1.0152 |
| C26:1 GlcCer | 2.6192 | 0.2646 | 0.5366 | 0.7346 |
| C26:1 HexCer | 2.4855 | 0.3306 | 0.5705 | 0.7583 |
| C26:1 Sphingomyelin | 2.6002 | 0.3646 | 0.4590 | 0.7824 |
| C26 Cer | 0.6421 | 0.4379 | 0.9728 | 2.0973 |
| C26DH 1-deoxyCer | 0.7486 | 0.7659 | 1.0775 | 1.3977 |
| C26DH Cer | 0.7325 | 1.1279 | 0.9060 | 1.3376 |
| C26DH HexCer | 0.9182 | 0.9017 | 0.9057 | 1.3726 |
| C26DH Sphingomyelin | 1.1215 | 0.7085 | 0.9606 | 1.2523 |
| C26 GalCer | 1.9797 | 1.2418 | 0.5043 | 0.4518 |
| C26 GlcCer | 2.3783 | 0.3176 | 0.6849 | 0.6972 |
| C26 HexCer | 2.3467 | 0.3909 | 0.6705 | 0.6779 |
| C26 Sphingomyelin | 1.2340 | 0.6419 | 0.8975 | 1.3058 |
| Sphinganine | 0.4407 | 0.2447 | 0.5078 | 3.3708 |
| Sphinganine-P | 0.3297 | 1.5516 | 1.0911 | 1.0114 |
| Sphingosine | 0.4383 | 0.5079 | 0.6290 | 2.8655 |
| Sphingosine-P | 0.0866 | 1.7871 | 1.2760 | 0.7077 |
Factors:
| F1 | Diagnosis:Cirrhosis |
| F2 | Diagnosis:NASH |
| F3 | Diagnosis:Normal |
| F4 | Diagnosis:Steatosis |
