Data for Multi-Platform Physiologic and Metabolic Phenotyping Reveals Microbial Toxicity (part II) (Study ST001008)
(Analysis AN001650)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 | F5 |
|---|---|---|---|---|---|
| 2-Keto-Isovalerate | 1.5788 | 1.4626 | 0.5240 | 0.0346 | 1.4000 |
| 2-Oxobutanoate | 0.9665 | 1.2677 | 1.2644 | 0.5798 | 0.9216 |
| 3-Methylphenylacetic Acid | 1.0776 | 0.7785 | 1.0030 | 1.1101 | 1.0308 |
| 4-Hydroxyphenyllactate | 1.7393 | 0.7010 | 1.4611 | 1.0977 | 0.0010 |
| 4-Pydroxybenzoate | 1.1573 | 0.9358 | 1.0634 | 1.0261 | 0.8175 |
| 4-Pyridoxic Acid | 1.2802 | 0.9586 | 1.1354 | 0.9665 | 0.6593 |
| 5-Aminopentanoic Acid | 1.0678 | 1.3240 | 1.3047 | 1.1324 | 0.1712 |
| Acetoacetate | 0.0544 | 0.9281 | 0.0607 | 0.0574 | 3.8994 |
| Acetyl-Glycine | 1.6648 | 0.9743 | 1.1968 | 0.9470 | 0.2171 |
| Adenine | 1.2230 | 0.9626 | 1.5385 | 0.8813 | 0.3947 |
| Alanine | 1.2021 | 0.9932 | 1.2335 | 1.3389 | 0.2322 |
| Aminolevulinate | 1.4305 | 0.8362 | 1.3599 | 1.2505 | 0.1229 |
| Arginine | 1.2461 | 0.8824 | 1.1074 | 1.4158 | 0.3484 |
| Ascorbic acid | 1.4342 | 0.7452 | 1.2364 | 1.3588 | 0.2255 |
| Asparagine | 1.1508 | 1.2765 | 1.3807 | 1.1893 | 0.0027 |
| Aspartate | 1.3209 | 0.8349 | 1.1932 | 1.4636 | 0.1874 |
| Aspartyl-Leucyl-Serine | 0.4025 | 2.0436 | 0.9600 | 1.5530 | 0.0409 |
| CDP | 1.7544 | 1.0111 | 1.9233 | 0.2591 | 0.0522 |
| CDP-Ethanolamine | 1.1347 | 1.0882 | 0.9584 | 1.1517 | 0.0010 |
| Citrate/Isocitrate | 1.0219 | 1.2822 | 1.1213 | 1.2754 | 0.2992 |
| Citrulline | 1.0952 | 0.9256 | 1.2408 | 1.2743 | 0.4641 |
| Cytidine | 1.1671 | 1.1540 | 1.3190 | 1.2291 | 0.1308 |
| dAMP | 1.6856 | 0.5427 | 1.2265 | 1.5407 | 0.0045 |
| dCMP | 1.4345 | 0.6712 | 1.0811 | 1.8132 | 0.0000 |
| Deoxyribose-phosphate | 1.0484 | 1.2810 | 1.0445 | 1.5971 | 0.0290 |
| Deoxyuridine | 1.2739 | 1.0385 | 1.1373 | 1.5428 | 0.0074 |
| D-Glucarate | 1.5057 | 0.4931 | 1.2501 | 1.4756 | 0.2753 |
| D-Gluconate | 1.5779 | 0.6491 | 1.6600 | 1.0616 | 0.0514 |
| D-Glyceraldehdye-3-Phosphate | 0.9168 | 0.9102 | 2.1834 | 0.9467 | 0.0428 |
| dGMP | 0.2790 | 0.1130 | 0.2409 | 0.2650 | 4.1021 |
| DL-Pipecolic Acid | 3.0041 | 0.7282 | 0.5549 | 0.7022 | 0.0105 |
| D-Sedoheptulose-1/7-Phosphate | 1.0917 | 1.8920 | 0.9365 | 0.9720 | 0.1078 |
| dTMP | 1.2947 | 0.8680 | 1.0416 | 1.7949 | 0.0009 |
| dUMP | 0.6030 | 1.3201 | 0.7380 | 1.2614 | 1.0775 |
| Fructose-1-6-Bisphosphate | 1.0123 | 1.3663 | 0.8937 | 1.0698 | 0.6579 |
| Fructose-6-Phosphate | 0.9787 | 0.9615 | 0.7325 | 1.9219 | 0.4055 |
| GDP | 2.4149 | 0.3639 | 1.9117 | 0.1443 | 0.1653 |
| Glucono-Lactone | 1.9274 | 1.0837 | 0.8833 | 1.1049 | 0.0008 |
| Glucose-6-Phosphate | 1.5012 | 0.8389 | 1.1673 | 1.0608 | 0.4318 |
| Glutamate | 1.3972 | 0.8744 | 1.2788 | 1.3593 | 0.0904 |
| Glutamine | 1.0993 | 1.1029 | 1.1758 | 1.4229 | 0.1992 |
| Glycerate | 1.4111 | 0.9952 | 1.2391 | 1.1776 | 0.1769 |
| Glycine | 1.1920 | 1.0108 | 1.2281 | 1.3755 | 0.1937 |
| Hexose-Phosphate | 1.1215 | 1.1509 | 1.2678 | 0.8926 | 0.5672 |
| Homocysteic Acid | 1.4557 | 0.8465 | 1.3404 | 1.1584 | 0.1991 |
| Hydroxyisocaproic acid | 0.8875 | 0.1232 | 1.3051 | 2.0684 | 0.6158 |
| Hydroxyphenylacetic Acid | 1.0739 | 0.9231 | 0.8339 | 0.9617 | 1.2074 |
| Hydroxyphenylpyruvate | 1.0284 | 0.8681 | 0.9923 | 0.9945 | 1.1167 |
| Inositol | 1.2241 | 0.7388 | 1.1447 | 1.3175 | 0.5749 |
| Isoleucyl-Aspartyl-Serine | 0.9347 | 1.2354 | 1.0456 | 1.6313 | 0.1529 |
| Ketoleucine | 1.3160 | 0.9362 | 1.3360 | 1.3465 | 0.0653 |
| Lactate | 1.4551 | 0.9398 | 1.1637 | 1.1354 | 0.3060 |
| Leucine/Isoleucine | 1.1948 | 0.9161 | 1.1642 | 1.3864 | 0.3385 |
| Leucyl-Aspartate | 1.2512 | 1.0952 | 1.3232 | 1.2290 | 0.1014 |
| Methionine | 1.2765 | 0.9134 | 1.1844 | 1.3973 | 0.2284 |
| Methylmalonic Acid | 1.6945 | 0.6826 | 1.2538 | 1.0100 | 0.3591 |
| N-Acetyl-Glucosamine-1/6-Phosphate | 1.4231 | 1.0919 | 1.2135 | 1.2352 | 0.0363 |
| N-Acetyl-Glutamine | 2.2766 | 0.3153 | 1.3096 | 1.0945 | 0.0040 |
| N-Acetyl-L-Alanine | 1.4504 | 0.8792 | 1.3150 | 1.3257 | 0.0297 |
| N-Acetyl-L-Ornithine | 1.4206 | 0.8560 | 1.2364 | 1.3012 | 0.1857 |
| Nicotinate | 1.4045 | 0.8749 | 1.1932 | 1.2296 | 0.2977 |
| Phenylpyruvate | 1.3286 | 0.8719 | 1.2761 | 1.3034 | 0.2201 |
| Proline | 1.4537 | 0.7884 | 1.2886 | 1.3081 | 0.1612 |
| Quinolinate | 1.1617 | 0.5270 | 1.2829 | 0.6005 | 1.4280 |
| Ribose | 1.1814 | 0.9700 | 1.2741 | 1.1665 | 0.4080 |
| Ribose-5-phosphate | 1.3037 | 1.5968 | 1.4375 | 0.5868 | 0.0753 |
| Ribulose-5-Phosphate | 0.9912 | 1.3779 | 0.9199 | 0.8253 | 0.8856 |
| Serine | 1.1619 | 1.0665 | 1.2062 | 1.4020 | 0.1634 |
| SN-Glycerol-3-Phosphate | 1.2193 | 1.1989 | 0.8651 | 1.0778 | 0.6390 |
| Taurine | 1.2226 | 0.9402 | 1.1818 | 1.1492 | 0.5063 |
| Threonine | 1.2522 | 0.9785 | 1.2382 | 1.4205 | 0.1106 |
| Trehalose/Sucrose | 1.2372 | 1.0214 | 1.3272 | 0.7955 | 0.6187 |
| Tryptophan | 1.2478 | 0.8835 | 1.1940 | 1.4096 | 0.2651 |
| UDP | 1.7845 | 1.0274 | 1.8550 | 0.2830 | 0.0501 |
| UMP | 1.2466 | 1.1171 | 1.1463 | 1.2594 | 0.2306 |
| Uric Acid | 0.0046 | 0.0022 | 0.0930 | 0.0096 | 4.8906 |
| Uridine | 1.3849 | 0.9337 | 1.1168 | 1.5174 | 0.0472 |
| Valyl-Aspartate | 1.3647 | 1.0297 | 1.3528 | 1.1588 | 0.0940 |
| Xanthine | 1.2024 | 0.9220 | 1.0986 | 1.6205 | 0.1565 |
Factors:
| F1 | Treatment:Control |
| F2 | Treatment:High Dose Tempol |
| F3 | Treatment:Low Dose Tempol |
| F4 | Treatment:Medium Dose Tempol |
| F5 | Treatment:PH4 |
