Data for TCA Concentrations in Neuromyelitis Optica Patients (part - II) (Study ST001036)
(Analysis AN001697)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 | F11 | F12 | F13 | F14 | F15 | F16 | F17 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2-Hydroxyglutarate | NA | 1.8753 | 1.9518 | NA | 1.9136 | 2.0284 | 1.8115 | 1.7987 | NA | 1.7987 | 0.0086 | 0.1875 | 0.0083 | 0.2143 | 0.0057 | 0.1958 | 2.0379 |
| Aspartate | 0.2451 | 0.2131 | 0.3078 | 0.3066 | 0.1545 | 0.2599 | 0.3169 | 0.1894 | 0.7810 | 0.1506 | 0.6731 | 4.0806 | 0.4392 | 2.8722 | 1.0695 | 4.4429 | 0.1271 |
| cis-Aconitic Acid | 1.0228 | 0.3254 | 0.4184 | 0.8679 | 0.6121 | 0.2247 | 0.7258 | 0.5941 | 2.3349 | 1.1210 | 0.4029 | 0.1829 | 0.7516 | 0.2862 | 0.5837 | 0.2092 | 2.9548 |
| Citrate | NA | 0.0189 | 0.0284 | NA | 0.0284 | 0.0095 | 0.1832 | 0.1986 | 0.1472 | 0.1566 | 0.0739 | 0.4250 | 0.0684 | 0.4687 | 0.0704 | 0.3973 | 6.0784 |
| Fumarate | 0.1539 | 0.7697 | 0.6158 | 0.2232 | 0.4233 | 0.6081 | 0.5696 | 1.3342 | 0.3977 | 1.3380 | 0.1963 | 1.6857 | 0.1822 | 2.4631 | 0.2104 | 1.9269 | 1.4560 |
| Glutamate | 2.0446 | 1.4763 | 0.1619 | 0.1994 | 0.2480 | 0.2204 | 0.0506 | 0.0201 | 0.0294 | 0.0394 | 1.2752 | 3.8018 | 0.7304 | 3.3278 | 1.1779 | 4.3272 | 0.0962 |
| Glutamine | 0.4468 | 0.4408 | 0.4063 | 0.4381 | 3.4690 | NA | 0.4629 | 0.4390 | 0.5095 | 3.6885 | NA | 0.1575 | NA | 0.1590 | 0.0021 | 0.1898 | 0.2607 |
| Isocitrate | NA | 0.4202 | 0.8403 | NA | 0.8403 | NA | 0.5602 | 0.8403 | NA | 0.7003 | NA | 0.7913 | NA | 0.8754 | NA | 0.7843 | 2.3109 |
| Ketoglutarate | 1.6801 | 0.1091 | 0.1091 | 3.8456 | 0.0873 | 0.1118 | 0.2764 | 0.2182 | 0.2709 | 0.2846 | 0.7337 | 2.8692 | 0.6018 | 2.7565 | 0.5655 | 3.0510 | 1.1710 |
| Lactate | 0.0379 | 0.0034 | 0.0052 | 0.0379 | 0.0228 | 0.0220 | 0.2078 | 0.1051 | 0.2320 | 0.1621 | 0.0059 | 0.0313 | 0.0055 | 0.0433 | 0.0053 | 0.0463 | 7.5315 |
| Malate | 0.1348 | 0.2157 | 0.2157 | 0.1240 | 0.1133 | 0.2535 | 0.3164 | 0.3595 | 0.2858 | 0.3487 | 0.8008 | 3.1423 | 0.7227 | 3.8685 | 0.7999 | 3.2178 | 0.7990 |
| Oxaloacetate | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Succinate | 0.5824 | 1.2481 | 1.2481 | 0.5755 | 0.9534 | 1.3937 | 1.2504 | 1.2018 | 0.8482 | 1.3821 | 0.1005 | 1.0239 | 0.0740 | 0.8528 | 0.0924 | 0.9291 | 1.5982 |
Factors:
| F1 | Time Point:0h | Matrix:Fresh Media | Condition:BGP 50uMGt Gn |
| F2 | Time Point:0h | Matrix:Fresh Media | Condition:BGP50uMGt Gn |
| F3 | Time Point:0h | Matrix:Fresh Media | Condition:BGPGt 0.5 mM Gn |
| F4 | Time Point:0h | Matrix:Fresh Media | Condition:BGPGt 0.5mM Gn |
| F5 | Time Point:0h | Matrix:Fresh Media | Condition:BGPGt 5mM Gn |
| F6 | Time Point:0h | Matrix:Fresh Media | Condition:E Med |
| F7 | Time Point:1h nonCO2 | Matrix:Spent Sup | Condition:BGP50uMGt Gn |
| F8 | Time Point:1h nonCO2 | Matrix:Spent Sup | Condition:BGPGt 0.5 mM Gn |
| F9 | Time Point:1h nonCO2 | Matrix:Spent Sup | Condition:BGPGt 0.5mM Gn |
| F10 | Time Point:1h nonCO2 | Matrix:Spent Sup | Condition:BGPGt 5mM Gn |
| F11 | Time Point:23h +1h nonCO2 | Matrix:pellet | Condition:BGP50uMGt Gn |
| F12 | Time Point:23h + 1h nonCO2 | Matrix:Pellet | Condition:BGP50uMGt Gn |
| F13 | Time Point:23h +1h nonCO2 | Matrix:pellet | Condition:BGPGt 0.5mM Gn |
| F14 | Time Point:23h + 1h nonCO2 | Matrix:Pellet | Condition:BGPGt 0.5 mM Gn |
| F15 | Time Point:23h +1h nonCO2 | Matrix:pellet | Condition:BGPGt 5mM Gn |
| F16 | Time Point:23h + 1h nonCO2 | Matrix:Pellet | Condition:BGPGt 5mM Gn |
| F17 | Time Point:23h | Matrix:Spent Sup | Condition:E Med |
