Data for Metabolme analysis of OPC-163493 on the Liver of ZDF rats (part-II) (Study ST001136)
(Analysis AN001863)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this studyMetabolite | F1 | F2 | F3 |
---|---|---|---|
Adenine | 1.0176 | 0.9327 | 1.0497 |
Adenosine | 1.4223 | 0.8270 | 0.7507 |
Alanine | 1.0048 | 1.0018 | 0.9934 |
Arginine | 1.0271 | 0.9422 | 1.0306 |
Argininosuccinic acid | 0.9028 | 1.0251 | 1.0721 |
Asparagine | 1.0853 | 0.9358 | 0.9789 |
Aspartic acid | 0.8957 | 1.0663 | 1.0380 |
Beta-Alanine | 1.0455 | 0.9278 | 1.0267 |
Betaine | 0.7404 | 0.9801 | 1.2795 |
Betaine aldehyde | 0.9037 | 1.0715 | 1.0248 |
Carnitine | 0.7979 | 1.1062 | 1.0959 |
Choline | 0.9094 | 1.0328 | 1.0578 |
cis-3-hydroxyproline | 1.2717 | 0.8389 | 0.8894 |
Citrulline | 1.0311 | 0.9179 | 1.0509 |
Creatine | 1.0377 | 0.9440 | 1.0183 |
Creatinine | 0.9706 | 1.0321 | 0.9973 |
Cystathionine | 1.1173 | 0.9170 | 0.9657 |
Cysteine | 0.7088 | 1.3473 | 0.9438 |
Dimethylglycine | 0.9788 | 0.8702 | 1.1510 |
Gamma-Aminobutyric acid | 0.9953 | 1.0265 | 0.9782 |
Glutamic acid | 1.0782 | 1.0432 | 0.8785 |
Glutamine | 0.9441 | 1.0669 | 0.9890 |
Glutathione | 1.0197 | 1.0513 | 0.9291 |
Glycine | 0.9778 | 0.9921 | 1.0301 |
Guanine | 1.0037 | 0.9074 | 1.0889 |
Guanosine | 1.2937 | 0.8888 | 0.8175 |
Histidine | 0.8867 | 1.0482 | 1.0652 |
Hypoxanthine | 1.2035 | 0.9574 | 0.8391 |
Inosine | 1.2673 | 0.9193 | 0.8134 |
Isoleucine | 0.9373 | 0.9688 | 1.0940 |
Leucine | 0.9528 | 0.9569 | 1.0903 |
Lysine | 0.9579 | 0.9781 | 1.0640 |
Methionine | 1.1191 | 0.8833 | 0.9975 |
Ornithine | 1.2478 | 0.9332 | 0.8190 |
Oxidized glutathione | 0.9962 | 0.8514 | 1.1525 |
Phenylalanine | 1.0387 | 0.9402 | 1.0210 |
Putrescine | 1.0015 | 0.9881 | 1.0121 |
S-Adenosylhomocysteine | 0.9085 | 1.0288 | 1.0627 |
S-Adenosylmethionine | 0.8794 | 1.0918 | 1.0288 |
Sarcosine | 0.9535 | 0.9400 | 1.1065 |
Serine | 1.0350 | 0.9777 | 0.9874 |
Spermidine | 0.8653 | 1.0058 | 1.1289 |
Spermine | 0.9570 | 1.0766 | 0.9664 |
Threonine | 0.9776 | 0.9879 | 1.0345 |
Tryptophan | 1.0378 | 0.9777 | 0.9845 |
Tyrosine | 1.0862 | 0.9664 | 0.9474 |
Urea | 0.8984 | 1.0253 | 1.0762 |
Valine | 0.8985 | 0.9897 | 1.1118 |
Factors:
F1 | Genotype:11-week-old ZDF rat | Treatment:- | Duration (weeks):- |
F2 | Genotype:17-week-old ZDF rat | Treatment:6 | Duration (weeks):6 |
F3 | Genotype:17-week-old ZDF rat | Treatment:- | Duration (weeks):6 |