Data for Genetic and metabolic characterization of bioengineered human fatty liver tissue with modified SIRT1 expression (Study ST001185)
(Analysis AN001969)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 |
|---|---|---|---|---|
| Adenosine | 0.3659 | 1.8516 | 1.2052 | NA |
| Alanine | 0.4823 | 1.6653 | 1.3702 | NA |
| Arginine | 1.9828 | 0.0099 | 0.0245 | NA |
| Aspartic acid | 0.8203 | 1.1994 | 1.1600 | NA |
| CAR(2:0) | NA | 1.3642 | 0.6358 | NA |
| Cis-Aconitic acid | 0.0172 | 2.1293 | 1.5087 | NA |
| Citric acid | 0.2207 | 0.9160 | 4.9804 | NA |
| Creatinine | NA | 1.2362 | 0.7638 | NA |
| Fructose-1,6-biphosphate | 0.3397 | 1.8853 | 0.7749 | NA |
| Fumaric acid | 0.2460 | 2.1910 | 1.3170 | NA |
| Glucose-6-phosphate | 0.1059 | 2.5262 | 0.6659 | NA |
| Glutamic acid | 0.8881 | 0.9710 | 1.2528 | NA |
| Glutamine | 1.6775 | 0.4358 | 0.2091 | NA |
| Hexose | 0.3360 | 2.0382 | 1.2898 | NA |
| Histidine | 1.5415 | 0.4187 | 0.4984 | NA |
| Itaconic acid | 0.2751 | 1.8077 | 1.6422 | NA |
| Lactic acid | 0.7684 | 1.2662 | 1.1970 | NA |
| Leucine | 1.2487 | 0.5904 | 0.9121 | NA |
| Lysine | 0.8907 | 0.8853 | 2.0000 | NA |
| Methionine | 1.3052 | 0.5194 | 0.8054 | NA |
| Ornithine | 0.4790 | 0.8116 | 2.0567 | NA |
| Oxoglutaric acid | 1.1002 | 0.8173 | 0.9824 | NA |
| Phosphoenolpyruvic acid | 1.0000 | NA | NA | NA |
| Pyruvic acid | NA | 1.2110 | 0.8593 | NA |
| Serine | 1.5472 | 0.3433 | 0.5624 | NA |
| Succinic acid | 0.8715 | 1.7169 | 0.5402 | NA |
| Tryptophan | 1.1960 | 0.5336 | 1.0743 | NA |
| Tyrosine | 1.4515 | 0.3946 | 0.7025 | NA |
| Valine | 1.4854 | 0.4080 | 0.6213 | NA |
Factors:
| F1 | Source:Bioengineered human iPS-derived fatty liver tissue-iKD-SIRT1 |
| F2 | Source:Healthy Control Liver Tissue |
| F3 | Source:NASH Liver Tissue from Patient |
| F4 | Source:Negative Control Empty Scaffold |
