Data for Effects of cold exposure on serum lipidomic in mice (Study ST001206)
(Analysis AN002008)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 |
|---|---|---|---|---|
| 10-HDHA | 0.6348 | 1.0599 | 0.8503 | 1.2221 |
| 11,12-diHETrE | 0.7402 | 0.5200 | 1.6173 | 1.4232 |
| 11(12)-EET | 0.8314 | 1.0436 | 0.9917 | 1.0530 |
| 11-beta-PGF2a/PGF2b | 0.6467 | 0.9439 | 1.2884 | 1.1264 |
| 11-dehydro TxB2 | NA | 1.0000 | NA | NA |
| 11-HDHA | 0.4454 | 1.1621 | 0.7445 | 1.1183 |
| 11-HEPE | 0.3065 | 1.2730 | 0.5363 | 1.3204 |
| 11-HETE | 0.4530 | 0.8316 | 0.6633 | 1.6986 |
| 12,13-diHOME | 0.8292 | 0.7982 | 1.3216 | 1.1838 |
| 12(13)-EpOME | 0.5009 | 1.2107 | 0.7651 | 1.1640 |
| 12-HEPE | 0.3445 | 0.8294 | 1.1040 | 1.5459 |
| 12-HETE | 0.3810 | 0.8723 | 0.8697 | 1.5899 |
| 12-oxoETE | 0.8216 | 0.9733 | 1.0507 | 1.1137 |
| 12-oxoLTB4 | 0.4258 | 1.7074 | 0.3062 | 0.9066 |
| 13,14-dihydro-15-keto PGA2 | 0.7856 | 1.2871 | 0.5466 | 0.9184 |
| 13,14-dihydro-15-keto PGD2 | 1.1338 | 0.9950 | 0.5053 | 1.1345 |
| 13,14-dihydro-15-keto PGE2 | 1.2287 | 0.9894 | 0.6575 | 0.9979 |
| 13,14-dihydro-15-keto PGF2a | 0.7340 | 0.6851 | 1.1446 | 1.6202 |
| 13,14-dihydro PGE1 | 0.9823 | 1.1657 | 0.5781 | 1.0228 |
| 13-HDHA | 1.1315 | 0.4260 | NA | 1.5176 |
| 13-HODE | 0.5013 | 1.2137 | 0.7585 | 1.1635 |
| 13-HOTrE/13-HOTrE(r) | 0.8335 | 1.1949 | 1.1295 | 0.8013 |
| 13-oxoODE | 0.7961 | 1.1680 | 0.9006 | 0.9704 |
| 14,15-diHETE | 1.8695 | 1.0368 | NA | 0.8683 |
| 14,15-diHETrE | 0.8390 | 0.5683 | 1.3643 | 1.4325 |
| 14(15)-EET | 0.6635 | 1.0701 | 0.8448 | 1.1953 |
| 14(15)-EpETE | 0.6975 | 1.0713 | 0.8816 | 1.1552 |
| 14-HDHA | 0.2309 | 0.9368 | 0.6833 | 1.6956 |
| 15-deoxy-delta12,14-PGD2 | 0.6451 | 0.9660 | 2.8501 | 0.9030 |
| 15-deoxy-delta12,14-PGJ2 | 0.8430 | 0.8636 | 1.2523 | 1.1003 |
| 15-HEPE | 0.5462 | 1.3271 | 0.7856 | 0.9742 |
| 15-HETE | 0.6856 | 0.9581 | 0.5125 | 1.4826 |
| 15-HETrE | 0.7445 | 1.0200 | 1.2669 | 0.9959 |
| 15-keto-PGE2 | 1.0000 | NA | NA | NA |
| 15-keto-PGF2a | 0.6439 | 1.0338 | 1.3391 | 0.9765 |
| 15-oxoETE | 0.6512 | 1.5014 | 0.5373 | 0.8390 |
| 16(17)-EpDPE | 0.7571 | 1.0123 | 0.8876 | 1.1872 |
| 16-HDHA | 0.8101 | 0.8877 | 1.1250 | 1.1862 |
| 16-HETE | 0.3691 | 0.8833 | 1.0776 | 1.4798 |
| 17,18-diHETE | 0.5829 | 0.8145 | 1.0422 | 1.4517 |
| 17(18)-EpETE | 0.9127 | 1.1261 | 0.7169 | 1.0426 |
| 17-HDHA | 0.9358 | 0.9663 | 0.3975 | 1.2905 |
| 17-HETE | 0.9671 | 0.7586 | 1.7291 | 0.9449 |
| 18-HEPE | 0.4368 | 1.4584 | 0.7253 | 0.9252 |
| 18-HETE | 0.8360 | 0.8967 | 1.2735 | 1.0856 |
| 19,20-diHDPA | 0.7647 | 0.8555 | 1.0681 | 1.2805 |
| 19(20)-EpDPE | 0.7047 | 0.8993 | 1.1458 | 1.2251 |
| 19/20-OH PGE2 | NA | 0.7104 | 1.0941 | 1.2971 |
| 19/20-OH PGF2a | 0.3134 | 1.1648 | 1.3570 | NA |
| 20-carboxy LTB4 | 1.0241 | 1.2071 | 0.7808 | NA |
| 20-HDHA | 0.8080 | 1.2505 | 0.5106 | 1.0659 |
| 20-HETE | 0.8113 | 0.8520 | 1.6635 | 0.9295 |
| 2,3-dinor-11beta-PGF2a | 0.7480 | 0.6560 | NA | 1.3133 |
| 2,3-dinor TxB2 | 0.7293 | 1.2644 | 0.7714 | 1.2413 |
| 4-HDHA | 0.4892 | 1.3946 | 0.5514 | 1.0573 |
| 5,15-diHETE | NA | 1.3943 | NA | 0.8029 |
| 5,6-diHETE | 0.3089 | 1.2966 | 0.7012 | 1.1102 |
| 5,6-diHETrE | 0.5431 | 1.5832 | 0.5012 | 0.8236 |
| 5(6)-EET | 0.7367 | 1.3133 | 0.7841 | 0.8899 |
| 5-HEPE | 0.5155 | 1.4155 | 0.7315 | 0.9263 |
| 5-HETE | 0.6142 | 1.5124 | 0.6194 | 0.8069 |
| 5-HETrE | 0.9834 | 1.1538 | 0.8805 | 0.8852 |
| 5-iPF2a-VI | 1.0381 | 0.8609 | 1.1540 | 1.0511 |
| 5-oxoETE | 0.8638 | 1.3742 | 0.9220 | 0.7339 |
| 6,15-diketo-13,14-dihydro PGF1a | 2.1978 | NA | 0.4011 | NA |
| 6-keto PGE1 | NA | 0.7082 | 1.2979 | 0.6960 |
| 6-keto-PGF1a | 0.5087 | 0.6808 | 0.5402 | 1.6715 |
| 7-HDHA | 0.6223 | 1.2741 | 0.4808 | 1.0174 |
| 8,9-diHETrE | 0.5241 | 1.3920 | 0.8033 | 0.9135 |
| 8(9)-EET | 0.7787 | 1.0836 | 0.9340 | 1.0654 |
| 8-HDHA | 0.8301 | 1.0636 | 0.6657 | 1.2846 |
| 8-HEPE | 0.4256 | 1.4200 | 0.4309 | 1.1252 |
| 8-HETE | 0.9074 | 1.0608 | 1.0587 | 0.9533 |
| 8-HETrE | 0.7702 | 1.0688 | 1.2581 | 0.9263 |
| 8-iso PGF2a | 0.5547 | 0.8496 | 1.5508 | 1.2324 |
| 9,10-diHOME | 0.8155 | 0.7312 | 1.4613 | 1.2026 |
| 9(10)-EpOME | 0.7376 | 0.8656 | 1.3288 | 1.1543 |
| 9-HEPE | 0.3002 | 1.0963 | 0.8369 | 1.3858 |
| 9-HETE | 0.6537 | 0.9717 | 0.7038 | 1.3899 |
| 9-HODE | 0.6238 | 1.2074 | 0.8751 | 1.0393 |
| 9-HOTrE | 0.7919 | 0.9833 | 1.3348 | 0.9776 |
| 9-oxoODE | 0.7869 | 1.1302 | 0.9897 | 0.9768 |
| Bicyclo PGE2 | 1.2269 | 1.0611 | 0.6041 | 0.9320 |
| d4-9-HODE | NA | NA | NA | NA |
| d4-LTB4 | NA | NA | NA | NA |
| d4-PGE2 | NA | NA | NA | NA |
| d8-5S-HETE | NA | NA | NA | NA |
| delta12-PGJ2 | 0.5776 | 1.0595 | 1.2979 | 1.0500 |
| Hepoxilin A3 | 0.5519 | 1.3244 | 0.5829 | 1.0990 |
| LTB4 | 0.6465 | 1.1797 | 0.7620 | 1.0246 |
| LTC4 | NA | NA | NA | 1.0000 |
| LTD4 | 1.4777 | NA | NA | 0.5223 |
| LTE4 | NA | NA | NA | 1.0000 |
| LXA4 | 0.4524 | 1.2293 | 1.1561 | 0.8777 |
| LXB4 | NA | 1.1460 | NA | 0.7566 |
| Maresin1 | NA | NA | NA | 1.0000 |
| PD1 | 1.2619 | 0.8983 | 0.9408 | 1.1218 |
| PGA1 | 0.5583 | 1.0920 | NA | 1.0207 |
| PGA2/PGJ2 | 0.5002 | 1.1378 | 1.1509 | 1.1283 |
| PGB2 | 0.8146 | 0.8034 | 1.0213 | 1.1858 |
| PGD2 | 0.6392 | 0.7847 | 1.8998 | 0.8064 |
| PGD3/PGE3 | 1.0385 | 0.9520 | NA | 1.0057 |
| PGE1/PGD1 | 1.1994 | 0.8719 | 1.0068 | 1.0475 |
| PGE2/PGD2 | 0.7556 | 0.9999 | 0.3556 | 1.4223 |
| PGF1a | 1.1067 | 0.9627 | 0.9656 | 0.9979 |
| PGF2a | 0.7119 | 0.8938 | 1.2841 | 1.0653 |
| PGK2 | 0.8927 | 1.0423 | NA | 1.0509 |
| RvD1 | NA | 0.9476 | 1.1724 | 0.8464 |
| RvD2 | 1.0393 | 0.9778 | 0.8996 | 1.0190 |
| Tetranor-12-HETE | 0.8647 | 0.7380 | 1.3726 | 1.2093 |
| tetranor-PGFM | 1.0897 | 0.8158 | 1.3792 | 1.0222 |
| TxB2 | 0.2176 | 0.1370 | 0.2052 | 2.8161 |
| TxB3 | 0.6578 | 0.4790 | 0.6369 | 1.7305 |
Factors:
| F1 | Temperature:22C | Time of exposure:1 hour |
| F2 | Temperature:30C | Time of exposure:7 days |
| F3 | Temperature:5C | Time of exposure:1 hour |
| F4 | Temperature:5C | Time of exposure:7 days |
