Data for Global Metabolic Analysis Trisomy 21 - Cohort 1 (Study ST001243)

(Analysis AN002065)

Values for each metabolite have been scaled by dividing by the mean across all factors

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MetaboliteF1F2
3-Methyleneoxindole 1.0735 0.9294
4-Acetamidobutanoate 0.7751 1.2159
5-Guanidino-2-oxopentanoate 0.7971 1.1899
5-Hydroxyindoleacetate 0.9005 1.0955
(5-L-Glutamyl)-L-glutamine 1.0660 0.9379
5-Oxoproline 1.0299 0.9713
Acetylcholine 1.0603 0.9421
Adenine 1.0232 0.9777
Allantoate 1.1333 0.8720
Anthranilate 1.3249 0.6946
Choline 1.0544 0.9478
Creatine 0.8717 1.1232
Creatinine 1.1072 0.8971
Cys-Gly 1.0429 0.9588
Dimethylglycine 0.9558 1.0424
gamma-L-Glutamyl-D-alanine 1.0582 0.9441
g-Oxalo-crotonate 1.0578 0.9445
Hexanoic acid 0.9758 1.0232
hexanoyl-L-carnitine 0.8141 1.1785
Hydroxybutyrylcarnitine 1.3977 0.6182
Hypoxanthine 1.0820 0.9212
Indole 1.0539 0.9483
Indole-3-acetaldehyde 1.0512 0.9509
Indole-3-acetate 0.9784 1.0207
Inosine 1.1967 0.7991
Isovalerylcarnitine 0.8677 1.1270
kynurenine 0.8793 1.1159
L-Adrenaline 0.9734 1.0255
L-Alanine 1.0033 0.9968
L-arginine 0.9735 1.0255
L-asparagine 0.9603 1.0381
L-Aspartate 1.0411 0.9605
L-Carnitine 1.3473 0.6889
L-Citrulline 0.9236 1.0733
L-cysteine 1.0408 0.9608
L-cystine 1.0449 0.9569
L-glutamate 1.0343 0.9671
L-glutamine 1.0147 0.9859
L-histidine 1.0151 0.9855
L-Homocysteine 1.0822 0.9211
L-leucine 1.0508 0.9513
L-lysine 1.0365 0.9650
L-methionine 1.0481 0.9538
L-Methionine S-oxide 1.0619 0.9405
L-phenylalanine 1.0106 0.9898
L-proline 1.0044 0.9958
L-serine 1.0627 0.9398
L-threonine 1.0324 0.9689
L-tryptophan 1.0454 0.9564
L-tyrosine 1.0485 0.9534
L-valine 1.0325 0.9688
N-Acetylornithine 0.7328 1.2565
octenoyl-l-carnitine 0.7376 1.2519
O-Decanoyl-L-carnitine 0.8613 1.1332
O-Decenoyl-L-carnitine 0.7701 1.2207
O-dodecenoyl-carnitine 0.7720 1.2189
Ornithine 1.1300 0.8752
Picolinic acid 0.9487 1.0492
Pyridoxal 0.7333 1.2326
Pyridoxamine phosphate 1.0440 0.9577
Quinolinic acid 0.6888 1.2925
Sarcosine 1.0032 0.9969
Serotonin 1.9863 0.0532
Sphingosine 1-phosphate 1.1672 0.8395
Taurine 1.0501 0.9519
Tiglylcarnitine 0.7495 1.2405
trans-4-Hydroxy-L-proline 0.9008 1.0952
Uracil 0.9365 1.0610
Xanthine 1.0019 0.9982
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Factors:

F1Cohort:D21
F2Cohort:T21
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