Data for Phenotyping Mouse blood metabolites in day and night in type 2 diabetes (Study ST001253)
(Analysis AN002082)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 |
|---|---|---|---|---|
| 1-palmitoyl-2-oleoyl-GPI (16:0/18:1) | 1.0231 | 0.7196 | 1.0391 | 1.1870 |
| 1-stearoyl-2-docosahexaenoyl-GPE (18:0/22:6) | 1.3757 | 1.2221 | 0.7861 | 0.7253 |
| 1-stearoyl-2-oleoyl-GPG (18:0/18:1) | 1.0402 | 0.7896 | 1.2427 | 0.9986 |
| 2,3-dihydroxyisovalerate | 0.6936 | 1.0685 | 1.4382 | 0.8662 |
| 2-hydroxybutyrate/2-hydroxyisobutyrate | 1.0350 | 1.5195 | 0.9650 | 0.5844 |
| 2-hydroxyphenylacetate | 1.9472 | 1.3567 | 0.6200 | 0.3743 |
| 2-oxoadipate | 1.0684 | 0.7550 | 1.3025 | 0.9735 |
| 3-hydroxy-3-methylglutarate | 1.3717 | 1.1717 | 0.9920 | 0.6444 |
| 3-hydroxyadipate | 1.5044 | 1.5771 | 0.9324 | 0.2762 |
| 3-hydroxybutyrate (BHBA) | 1.8951 | 0.9371 | 1.2263 | 0.3774 |
| 3-hydroxyisobutyrate | 1.4148 | 0.9302 | 1.1807 | 0.6985 |
| 3-methyl-2-oxobutyrate | 1.0056 | 0.8520 | 1.1637 | 1.0168 |
| 3-methylglutaconate | 1.1668 | 1.2321 | 0.9649 | 0.7354 |
| 3-methylglutarate/2-methylglutarate | 1.6694 | 0.9809 | 1.4086 | 0.3685 |
| acetylphosphate | 1.2359 | 0.8751 | 1.4886 | 0.6652 |
| adipate (C6-DC) | 1.1926 | 1.1947 | 1.0025 | 0.7272 |
| alanine | 0.9415 | 1.0934 | 1.0877 | 0.9078 |
| allantoic acid | 1.6353 | 0.9983 | 0.9330 | 0.6604 |
| allantoin | 1.0017 | 1.0937 | 0.9370 | 0.9618 |
| alpha-ketoglutaramate | 0.9375 | 1.4571 | 0.7388 | 0.8285 |
| alpha-ketoglutarate | 1.1842 | 0.9256 | 1.1385 | 0.8659 |
| arabitol/xylitol | 0.7811 | 1.2079 | 0.8075 | 1.0806 |
| arabonate/xylonate | 1.9451 | 1.3008 | 0.5374 | 0.4699 |
| caffeic acid sulfate | 2.2385 | 0.8737 | 0.9124 | 0.4105 |
| cysteine s-sulfate | 1.7964 | 1.0104 | 0.9021 | 0.5725 |
| cystine | 0.6087 | 1.1660 | 1.0172 | 1.0916 |
| dihydroorotate | 0.0203 | 3.4844 | 0.0203 | 0.1881 |
| erythritol | 0.8132 | 1.5965 | 0.6273 | 0.8585 |
| erythronate | 1.4227 | 1.4753 | 0.7488 | 0.5168 |
| ethylmalonate | 1.5753 | 1.2858 | 0.5996 | 0.6664 |
| fructose | 2.3657 | 1.2465 | 0.5914 | 0.2285 |
| fumarate | 0.7512 | 1.4448 | 0.8374 | 0.8910 |
| gamma-glutamylthreonine | 0.5989 | 0.5954 | 1.5665 | 1.2244 |
| gentisate | 2.2312 | 0.5072 | 1.3590 | 0.4402 |
| gluconate | 1.2304 | 2.2372 | 0.4288 | 0.2147 |
| glucose | 1.7673 | 1.4627 | 0.6390 | 0.3861 |
| glucuronate | 1.2193 | 1.2862 | 0.6920 | 0.8242 |
| glutarate (C5-DC) | 1.1258 | 0.8497 | 1.2339 | 0.9044 |
| glycerate | 1.5881 | 1.1122 | 0.8768 | 0.6312 |
| glycerophosphoglycerol | 0.9439 | 1.8386 | 0.7281 | 0.5259 |
| glycerophosphoinositol | 0.9115 | 1.1666 | 0.7965 | 1.0419 |
| glycolate (hydroxyacetate) | 1.6208 | 0.8742 | 1.2747 | 0.5633 |
| guanidinoacetate | 0.6022 | 0.9066 | 1.0255 | 1.2981 |
| gulonate | 1.2576 | 1.0426 | 1.0791 | 0.7639 |
| heptenedioate (C7:1-DC) | 0.8892 | 1.7900 | 0.6465 | 0.6465 |
| hypotaurine | 0.9150 | 0.6902 | 1.3442 | 1.0924 |
| isocitric lactone | 1.0814 | 1.3023 | 1.0086 | 0.7041 |
| itaconate | 1.5249 | 1.8154 | 0.4043 | 0.3902 |
| lactate | 0.7084 | 1.3567 | 0.7251 | 1.0545 |
| maleate | 1.1168 | 0.8728 | 1.0007 | 1.0313 |
| malonate | 1.1160 | 0.9838 | 1.1391 | 0.8599 |
| mannitol/sorbitol | 0.5143 | 2.0307 | 0.2383 | 0.9239 |
| mannose | 1.6577 | 1.2877 | 0.8375 | 0.4727 |
| methylmalonate (MMA) | 0.8621 | 1.3976 | 0.8958 | 0.8272 |
| methylsuccinate | 1.5487 | 1.3235 | 0.7003 | 0.5918 |
| myo-inositol | 0.9998 | 1.2577 | 1.0096 | 0.7882 |
| N2-acetyllysine | 0.7005 | 0.8459 | 1.2782 | 1.1361 |
| N6-acetyllysine | 0.7867 | 0.8698 | 1.4530 | 0.9603 |
| N-acetylalanine | 1.2072 | 0.9767 | 1.0025 | 0.8928 |
| N-acetylaspartate (NAA) | 0.7779 | 0.7256 | 1.1795 | 1.2451 |
| N-acetylglutamate | 1.7641 | 0.7647 | 1.2694 | 0.5682 |
| N-acetylglutamine | 1.0376 | 0.9207 | 1.0387 | 1.0177 |
| N-acetylglycine | 1.0780 | 0.6226 | 1.2851 | 1.0841 |
| N-acetylneuraminate | 1.0887 | 1.1250 | 0.9557 | 0.8734 |
| N-acetylserine | 0.8657 | 0.8849 | 1.2652 | 1.0135 |
| N-carbamoylaspartate | 0.1865 | 3.0861 | 0.1094 | 0.3536 |
| N-formylanthranilic acid | 1.1872 | 0.7999 | 1.2396 | 0.9040 |
| N-glycolylneuraminate | 0.6331 | 1.8253 | 0.5113 | 0.8532 |
| orotate | 0.3760 | 2.6112 | 0.3384 | 0.4824 |
| orotidine | 1.1824 | 1.0907 | 0.8501 | 0.9079 |
| perfluorooctanesulfonic acid (PFOS) | 1.1044 | 1.1849 | 1.0114 | 0.7826 |
| pimelate (C7-DC) | 1.8784 | 1.1850 | 0.8858 | 0.3935 |
| pyruvate | 0.8930 | 0.7767 | 0.7870 | 1.3707 |
| quinate | 1.6734 | 1.1592 | 1.1841 | 0.3581 |
| quinolinate | 0.8717 | 0.4222 | 2.1204 | 0.8670 |
| ribitol | 0.1396 | 1.8560 | 0.1703 | 1.3293 |
| ribonate | 1.8517 | 1.0578 | 0.9041 | 0.5003 |
| ribose | 2.9517 | 0.7005 | 0.9179 | 0.1179 |
| ribose 1-phosphate | 1.2260 | 1.4728 | 1.6306 | 0.1078 |
| ribulonate/xylulonate | 1.6736 | 1.2791 | 0.7225 | 0.5391 |
| ribulose/xylulose 5-phosphate | 1.2411 | 0.8498 | 2.0564 | 0.3417 |
| salicylate | 1.3744 | 0.9143 | 1.2918 | 0.6688 |
| sedoheptulose | 1.7063 | 1.2874 | 0.8553 | 0.4331 |
| sphingosine 1-phosphate | 1.3290 | 1.2476 | 1.0940 | 0.5481 |
| succinate | 0.6632 | 2.0024 | 0.5559 | 0.6666 |
| sucrose | 1.2770 | 0.1086 | 3.4833 | 0.0570 |
| threonate | 1.2660 | 1.1786 | 0.8857 | 0.7661 |
| tricarballylate | 1.2781 | 0.9921 | 1.7688 | 0.3782 |
| xylose | 0.2811 | 0.8633 | 1.3194 | 1.3491 |
Factors:
| F1 | diabetes:db/db | time of day:ZT17 |
| F2 | diabetes:db/db | time of day:ZT5 |
| F3 | diabetes:db/m | time of day:ZT17 |
| F4 | diabetes:db/m | time of day:ZT5 |
