Data for Eicosanoid profiles of dermal fibroblasts (part-II) (Study ST001254)

(Analysis AN002083)

Values for each metabolite have been scaled by dividing by the mean across all factors

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Metabolite	F1	F2	F3	F4	F5	F6	F7	F8
(±)11,12-DHET	0.4968	0.2360	0.4654	1.6395	0.3211	1.5620	0.4841	0.4464
12 HETE	0.1597	0.0239	0.1757	2.4536	0.0874	1.1660	0.1685	0.0425
(±)14,15-DHET	0.4431	0.2840	0.4245	1.5933	0.3490	1.6217	0.4141	0.4931
(±)14(15)-EET	0.4650	0.3398	0.5617	1.8724	0.3525	1.0670	0.7504	0.4603
15 HETE	0.5767	0.3700	0.6610	1.8170	0.3065	1.0299	0.6292	0.6391
20-HETE	1.4245	0.7581	1.2397	0.7019	1.3827	0.9072	1.2144	1.4595
5 HETE	0.2129	3.8377	0.1952	1.3021	0.0922	0.5320	0.1865	0.0847
6-keto PGF1α	0.0233	1.9836	0.0305	0.0082	0.0090	2.0125	0.0236	3.4031
(±)8,9-DHET	0.2845	0.2069	0.3428	1.7070	0.1919	1.5423	0.3350	0.4163
PGA2	0.7352	0.7258	0.7767	0.8357	0.7675	1.5297	0.7647	1.3609
PGE1	0.2585	1.0938	0.3102	0.2758	0.1223	2.5431	0.2922	1.8459
PGE2	0.2185	1.6183	0.2352	0.2210	0.1170	1.9165	0.2419	2.8925
PGF2α	0.3062	1.4606	0.3462	0.4237	0.0952	1.8586	0.3415	2.4044
Resolvin D1	1.0940	0.5409	1.0808	1.0353	1.0642	1.0621	1.0732	1.0941
TXB2	0.2041	0.1187	0.2150	1.9188	0.1283	1.6900	0.2224	0.2152

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Factors:

F1	Genotype:cPLA2α KI | Treatment:Pyrrophenone (50nM)
F2	Genotype:cPLA2α KI | Treatment:Untreated
F3	Genotype:cPLA2α KO | Treatment:CMV control Virus
F4	Genotype:cPLA2α KO | Treatment:cPLA2α KI Virus
F5	Genotype:cPLA2α KO | Treatment:Pyrrophenone (50nM)
F6	Genotype:cPLA2α KO | Treatment:Wild Type Virus
F7	Genotype:Wild Type | Treatment:Pyrrophenone (50nM)
F8	Genotype:Wild Type | Treatment:Untreated