Data for Atg32-mediated mitophagy promotes heat stress tolerance in Saccharomyces cerevisiae by sustaining spermidine and nitric oxide levels (Study ST001318)
(Analysis AN002194)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this studyMetabolite | F1 | F2 | F3 | F4 | F5 | F6 |
---|---|---|---|---|---|---|
2,5-dihydroxypyrazine NIST | 1.0317 | 0.9256 | 0.9497 | 1.0132 | 1.0883 | 0.9914 |
2-hydroxyglutaric acid | 0.5632 | 0.6324 | 0.7764 | 1.0624 | 1.4708 | 1.4948 |
2-methylglyceric acid NIST | 0.9370 | 1.0398 | 1.0174 | 0.8599 | 1.2105 | 0.9354 |
3-aminoisobutyric acid | 0.8802 | 0.8414 | 1.5723 | 0.7224 | 0.9967 | 0.9870 |
3-hydroxy-3-methylglutaric acid | 1.1058 | 1.0637 | 1.0673 | 0.8026 | 0.9635 | 0.9971 |
3-phosphoglycerate | 1.3547 | 0.9392 | 1.4450 | 0.5615 | 0.6352 | 1.0644 |
4-aminobutyric acid | 1.6959 | 0.7063 | 0.7343 | 0.8381 | 1.2372 | 0.7882 |
5^-deoxy-5^-methylthioadenosine | 1.2171 | 0.8530 | 0.8978 | 0.8774 | 0.9719 | 1.1828 |
5-methoxytryptamine | 1.1838 | 0.7641 | 0.9930 | 1.1956 | 0.9246 | 0.9391 |
aconitic acid | 0.9191 | 0.8388 | 0.8779 | 1.1203 | 0.8793 | 1.3646 |
adenine | 1.0666 | 0.7973 | 0.9295 | 0.9506 | 0.9057 | 1.3502 |
adenosine | 0.8302 | 1.0366 | 1.0990 | 0.9932 | 1.2052 | 0.8358 |
adenosine-5-monophosphate | 1.0014 | 0.9431 | 1.1953 | 0.7403 | 1.0496 | 1.0702 |
adrenaline | 0.9729 | 1.0389 | 1.0286 | 0.9441 | 1.0441 | 0.9715 |
alanine | 0.9362 | 0.9465 | 0.9945 | 0.9301 | 1.0942 | 1.0986 |
alanine-alanine | 0.7573 | 1.1463 | 1.3691 | 0.8745 | 0.9933 | 0.8594 |
allothreonine | 2.0861 | 1.1220 | 1.4447 | 0.3083 | 0.4506 | 0.5883 |
alpha-ketoglutarate | 0.3604 | 0.8086 | 0.9101 | 0.9358 | 1.4131 | 1.5720 |
aminomalonate | 0.9161 | 0.5458 | 1.1067 | 0.9480 | 1.3383 | 1.1451 |
arachidic acid | 1.1894 | 1.0261 | 1.1527 | 0.8522 | 0.8759 | 0.9037 |
asparagine | 0.8574 | 0.9706 | 1.0930 | 1.0067 | 1.0412 | 1.0311 |
aspartic acid | 0.9167 | 0.9748 | 1.0928 | 1.0403 | 1.0658 | 0.9096 |
beta-glycerolphosphate | 1.0928 | 0.9762 | 0.9707 | 0.7250 | 0.9977 | 1.2376 |
beta-mannosylglycerate | 1.6235 | 0.6329 | 0.8536 | 1.3698 | 0.5695 | 0.9507 |
biphenyl | 0.9242 | 0.6253 | 0.8566 | 1.1610 | 1.3173 | 1.1156 |
butane-2,3-diol NIST | 0.6683 | 0.9138 | 1.1248 | 0.8517 | 1.3151 | 1.1262 |
butyrolactam NIST | 0.9057 | 1.1620 | 0.9209 | 0.9320 | 1.1770 | 0.9024 |
citric acid | 0.4964 | 0.7221 | 0.8154 | 1.1417 | 1.2804 | 1.5439 |
citrulline | 1.2732 | 1.5967 | 0.8681 | 0.7562 | 0.7911 | 0.7147 |
conduritol-beta-epoxide | 1.0148 | 0.9775 | 1.1032 | 1.0202 | 1.0712 | 0.8131 |
cysteine | 0.6325 | 1.0209 | 1.2752 | 0.7272 | 1.1653 | 1.1789 |
cysteine-glycine | 0.6313 | 0.8530 | 1.1808 | 0.7280 | 1.4220 | 1.1849 |
cytidine-5-monophosphate | 1.1471 | 1.2671 | 1.1892 | 0.6759 | 0.8518 | 0.8690 |
ergosterol | 0.8023 | 0.8097 | 0.8518 | 1.2043 | 0.8566 | 1.4752 |
ethanol phosphate NIST | 1.3488 | 0.8411 | 0.9895 | 0.9783 | 0.9733 | 0.8690 |
fructose | 0.8781 | 1.0366 | 1.2026 | 0.8160 | 0.9284 | 1.1383 |
fructose-6-phosphate | 0.7136 | 1.0832 | 1.2362 | 0.5964 | 1.1327 | 1.2380 |
fumaric acid | 0.9774 | 0.7582 | 1.0002 | 0.8607 | 1.1306 | 1.2729 |
galactinol | 1.4248 | 1.9961 | 0.7978 | 0.4301 | 0.9504 | 0.4008 |
galactose | 0.4355 | 0.6738 | 0.7298 | 1.5073 | 1.2177 | 1.4359 |
gluconic acid | 1.1269 | 1.1039 | 0.9092 | 0.8654 | 0.9843 | 1.0103 |
glucose | 0.5067 | 0.7739 | 0.9014 | 1.3613 | 1.1492 | 1.3074 |
glucose-1-phosphate | 0.9907 | 1.4856 | 1.1827 | 0.6266 | 0.7589 | 0.9555 |
glucose-6-phosphate | 0.5355 | 1.0911 | 1.5230 | 0.3280 | 1.1824 | 1.3399 |
glutamic acid | 1.0935 | 0.8991 | 1.0482 | 0.9245 | 0.9862 | 1.0485 |
glutamine | 0.8503 | 0.9683 | 1.2248 | 0.9826 | 0.9623 | 1.0118 |
glyceric acid | 0.8801 | 1.0262 | 1.1934 | 1.1054 | 0.8216 | 0.9732 |
glycerol | 0.9344 | 1.3294 | 0.9576 | 1.3755 | 0.8260 | 0.5771 |
glycerol-3-galactoside | 1.0036 | 1.0674 | 1.1999 | 0.5750 | 1.0706 | 1.0835 |
glycerol-alpha-phosphate | 0.7537 | 0.5572 | 0.7967 | 1.0608 | 1.2565 | 1.5751 |
glycine | 0.8928 | 0.8486 | 1.0095 | 0.7868 | 1.0235 | 1.4388 |
glycolic acid | 0.9844 | 0.8940 | 1.6462 | 1.0498 | 0.6948 | 0.7308 |
glycyl-proline | 0.7964 | 0.8481 | 0.7808 | 1.0872 | 1.0695 | 1.4181 |
glycyl tyrosine | 0.8906 | 0.9242 | 1.0176 | 0.9341 | 1.1296 | 1.1039 |
guanine | 1.0574 | 1.0337 | 1.0745 | 1.0003 | 0.9311 | 0.9030 |
guanosine | 0.7569 | 0.9814 | 1.0747 | 1.0027 | 1.1326 | 1.0517 |
heptadecanoic acid | 1.1731 | 1.1878 | 1.0456 | 0.8142 | 1.0199 | 0.7595 |
hexose-6-phosphate | 0.9389 | 1.0743 | 1.4266 | 0.6048 | 0.9435 | 1.0120 |
histidine | 1.0846 | 0.7166 | 0.8062 | 0.8730 | 1.1131 | 1.4066 |
homoserine | 0.9275 | 0.9776 | 1.1410 | 1.0987 | 0.9682 | 0.8871 |
hydroxycarbamate NIST | 0.9230 | 1.0034 | 1.1407 | 1.0094 | 0.9732 | 0.9503 |
hydroxylamine | 0.9226 | 1.2763 | 1.0066 | 1.0241 | 0.9249 | 0.8455 |
inosine | 1.0513 | 0.8483 | 0.7570 | 1.2397 | 0.9811 | 1.1226 |
inositol-4-monophosphate | 0.9915 | 1.0662 | 1.4395 | 0.5782 | 0.8729 | 1.0518 |
isocitric acid | 0.5799 | 0.8175 | 0.7280 | 1.1400 | 1.2147 | 1.5199 |
isoleucine | 0.8724 | 0.9702 | 1.0119 | 1.0381 | 1.1211 | 0.9862 |
isothreonic acid | 0.6744 | 1.0516 | 1.0438 | 1.1072 | 1.2408 | 0.8822 |
lactic acid | 1.0628 | 1.0523 | 1.2019 | 1.0483 | 0.9889 | 0.6458 |
lactulose | 0.7565 | 0.9358 | 1.1033 | 1.1084 | 1.0449 | 1.0510 |
lauric acid | 1.2161 | 0.8383 | 0.7835 | 0.7433 | 1.5711 | 0.8477 |
leucine | 1.1751 | 0.9384 | 1.0453 | 0.9315 | 0.9354 | 0.9743 |
levoglucosan | 0.8784 | 0.9765 | 1.0387 | 0.7616 | 0.9380 | 1.4069 |
lysine | 1.1786 | 0.8834 | 0.8464 | 1.0649 | 0.9388 | 1.0880 |
maleimide | 0.7442 | 0.8254 | 1.0058 | 1.1943 | 1.3631 | 0.8672 |
malic acid | 0.9758 | 0.7710 | 0.9518 | 0.8713 | 1.1538 | 1.2761 |
methanolphosphate | 0.7171 | 0.8190 | 0.9758 | 0.8145 | 1.2027 | 1.4709 |
methionine | 0.6753 | 1.1342 | 1.0335 | 0.8454 | 1.1989 | 1.1128 |
methionine sulfoxide | 1.2403 | 0.9036 | 0.9362 | 1.0515 | 0.9870 | 0.8814 |
myo-inositol | 0.8771 | 0.6651 | 0.8130 | 0.9940 | 1.2234 | 1.4274 |
myristic acid | 1.0403 | 1.0593 | 1.0871 | 0.9767 | 0.9763 | 0.8604 |
N-carbamylglutamate | 0.9740 | 1.5092 | 1.0486 | 0.7803 | 0.7908 | 0.8972 |
n-epsilon-trimethyllysine | 1.0611 | 0.9026 | 0.8515 | 0.9619 | 1.1559 | 1.0670 |
nicotinamide | 0.9416 | 1.0925 | 1.3334 | 0.6964 | 0.9074 | 1.0286 |
nicotinic acid | 0.7500 | 1.1204 | 1.0376 | 0.9599 | 1.1994 | 0.9327 |
N-methylalanine | 1.2257 | 1.1947 | 1.2757 | 0.5089 | 0.7920 | 1.0029 |
oleic acid | 1.1433 | 0.9258 | 1.7088 | 0.7330 | 0.6932 | 0.7959 |
ornithine | 1.2013 | 0.7370 | 0.8026 | 1.1580 | 1.0861 | 1.0151 |
orotic acid | 1.4122 | 1.6006 | 1.9911 | 0.1952 | 0.3758 | 0.4251 |
oxalic acid | 1.0578 | 0.9647 | 1.6495 | 0.6034 | 0.8780 | 0.8466 |
oxoproline | 0.8469 | 1.0537 | 1.1556 | 0.9802 | 1.0756 | 0.8879 |
palmitic acid | 1.1211 | 1.0444 | 1.0727 | 0.8524 | 0.9672 | 0.9422 |
palmitoleic acid | 0.8066 | 0.7832 | 1.6348 | 0.8670 | 0.9169 | 0.9915 |
parabanic acid NIST | 0.7791 | 1.4954 | 0.8372 | 0.9175 | 1.1521 | 0.8187 |
pelargonic acid | 1.0812 | 0.9703 | 1.1317 | 0.9130 | 1.0140 | 0.8899 |
pentadecanoic acid | 1.2019 | 0.8352 | 1.0635 | 0.9614 | 1.0788 | 0.8592 |
phenylalanine | 0.9714 | 0.9576 | 1.0433 | 1.0025 | 1.0854 | 0.9399 |
phosphate | 1.0779 | 0.7348 | 0.8508 | 1.1062 | 0.9103 | 1.3200 |
phosphoenolpyruvate | 0.9868 | 1.0761 | 1.3999 | 0.6549 | 0.8111 | 1.0711 |
phosphogluconic acid | 0.9956 | 1.0890 | 1.5996 | 0.7586 | 0.8207 | 0.7365 |
pipecolinic acid | 0.6477 | 0.9800 | 1.3515 | 0.6744 | 1.3418 | 1.0045 |
proline | 1.1229 | 1.2178 | 1.1695 | 0.8698 | 0.8247 | 0.7951 |
propane-1,3-diol NIST | 1.1023 | 0.9723 | 1.2631 | 0.9152 | 0.8236 | 0.9235 |
pseudo uridine | 1.4582 | 0.7682 | 1.2405 | 0.8720 | 0.7657 | 0.8954 |
putrescine | 1.7634 | 0.7949 | 0.8309 | 0.8778 | 0.9053 | 0.8277 |
pyrophosphate | 1.1303 | 0.7226 | 1.1483 | 0.9162 | 0.9846 | 1.0980 |
pyruvic acid | 0.7384 | 1.0350 | 1.5321 | 0.9120 | 0.9254 | 0.8571 |
ribitol | 1.0166 | 1.0764 | 1.0260 | 0.8040 | 0.9429 | 1.1341 |
ribonic acid | 0.9346 | 1.0044 | 1.1100 | 0.8686 | 1.1038 | 0.9786 |
saccharopine | 0.6522 | 0.7458 | 0.9649 | 1.0777 | 1.2184 | 1.3410 |
serine | 1.0587 | 0.9407 | 1.1439 | 0.8589 | 1.0210 | 0.9768 |
sorbitol | 0.8481 | 1.0362 | 1.0995 | 0.6456 | 1.1440 | 1.2266 |
spermidine | 2.4529 | 0.5043 | 0.8689 | 0.9809 | 0.7302 | 0.4627 |
stearic acid | 1.2394 | 1.1258 | 1.0546 | 0.8047 | 0.9446 | 0.8309 |
succinic acid | 1.1759 | 0.9914 | 1.0395 | 0.4818 | 1.1875 | 1.1238 |
sucrose | 0.7137 | 0.6458 | 1.6045 | 1.9095 | 0.4843 | 0.6422 |
sulfuric acid | 0.4955 | 2.4665 | 2.0080 | 0.4182 | 0.1479 | 0.4638 |
threonine | 1.0119 | 1.0227 | 1.1615 | 0.7794 | 0.9848 | 1.0397 |
thymine | 0.9888 | 1.0221 | 1.0944 | 0.9160 | 1.1651 | 0.8135 |
trans-4-hydroxyproline | 0.7311 | 1.2167 | 1.1840 | 1.0709 | 0.8693 | 0.9280 |
trehalose | 0.7510 | 1.1696 | 1.0219 | 0.9035 | 1.0518 | 1.1023 |
trehalose-6-phosphate | 0.8859 | 1.0429 | 1.0346 | 0.8486 | 1.0886 | 1.0994 |
tryptophan | 0.9515 | 0.9828 | 1.0119 | 0.9807 | 1.1237 | 0.9495 |
tyrosine | 1.0025 | 0.8695 | 0.9480 | 1.0659 | 1.0416 | 1.0723 |
tyrosol | 1.2555 | 0.9884 | 0.8414 | 1.0046 | 0.8058 | 1.1042 |
UDP-N-acetylglucosamine | 1.4989 | 0.9633 | 0.9419 | 0.7756 | 0.6762 | 1.1441 |
uracil | 0.6843 | 1.0650 | 1.3002 | 0.9920 | 1.0729 | 0.8856 |
urea | 0.8455 | 1.0358 | 1.0729 | 1.0994 | 1.0512 | 0.8952 |
uridine | 0.9151 | 0.9507 | 0.9806 | 1.1002 | 0.9429 | 1.1106 |
uridine-5^-monophosphate | 1.3368 | 1.0220 | 1.1173 | 0.7168 | 0.9305 | 0.8765 |
valine | 1.0141 | 0.9539 | 1.0584 | 0.9276 | 1.0487 | 0.9973 |
xanthine | 0.8106 | 0.9716 | 0.8539 | 0.9917 | 1.1494 | 1.2229 |
Factors:
F1 | Treatment:1 - WT_30 |
F2 | Treatment:2 - datg3_30 |
F3 | Treatment:3 - datg32_30 |
F4 | Treatment:4 - WT_37 |
F5 | Treatment:5 - datg3_37 |
F6 | Treatment:6 - datg32_37 |