Data for Core Functional Nodes and Sex-Specific Pathways in Human Ischemic and Dilated Cardiomyopathy (Study ST001364)

(Analysis AN002270)

Values for each metabolite have been scaled by dividing by the mean across all factors

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Metabolite	F1	F2	F3	F4	F5	F6
1-methylhistamine	1.0378	0.9648	0.9957	1.0030	1.0535	0.9874
2-deoxyadenosine	1.0686	1.1776	0.6699	0.9330	1.5061	0.8638
2-deoxycytidine	0.8439	1.1549	0.4925	0.3326	1.0677	1.7780
2-Methylbutyrylcarnitine	0.0839	0.0939	3.8482	1.4763	0.1427	0.0903
5-Aminolevulinic-Acid	0.8485	0.8849	1.2262	1.0535	0.9992	0.9613
5-HIAA	0.8445	0.9690	1.2900	0.8447	0.9698	0.9974
Acetoacetic-Acid	0.8492	0.9463	1.0736	1.1016	0.8935	1.0469
Acetylcarnitine	0.8806	0.8767	1.1382	0.9890	0.9666	1.0845
Acetylcholine	0.7790	0.7787	1.2559	1.1108	0.6185	1.2181
Adenosine	0.9448	1.2412	0.4899	0.5640	1.2539	1.3968
ADMA	0.8500	1.3836	1.0585	0.5848	0.7229	1.1122
Alanine	0.7865	0.8553	1.3037	1.0114	0.8942	1.0390
Aminoadipic-Acid	0.4589	0.9261	1.5617	0.7829	1.0663	1.0064
Anserine	0.5990	0.8411	0.9721	0.4280	0.9118	1.8104
Arginine	0.7139	1.0075	1.1321	0.5430	1.0925	1.3042
Asparagine	0.7431	1.0612	1.2383	1.1195	0.9062	0.8460
Aspartate	0.8822	1.1326	0.7206	1.3120	0.6340	1.1277
beta-Alanine	0.8928	0.9587	1.0673	0.9682	1.2410	0.9387
Betaine	1.0467	1.0234	0.9433	1.0543	1.0466	0.9397
Butyrlcarnitine	0.8833	0.8990	1.1688	1.0567	0.9713	0.9888
Carnitine	0.9394	0.9491	1.0525	0.9701	0.9586	1.0758
Carnosine	0.9102	1.3531	0.8081	0.3260	1.4819	1.1114
Choline	0.9197	0.9561	0.6725	1.0866	0.8906	1.3358
Citrulline	0.6796	1.1463	0.5085	0.3964	0.9638	1.8623
Creatine	1.0893	0.9055	0.9880	1.0603	1.0206	0.9975
Cystamine	1.6612	1.4078	0.4687	0.3208	0.5708	1.4174
Cysteamine	0.6958	1.0113	1.1183	0.3196	0.6359	1.7056
Cysteine	0.8457	1.3030	0.9887	0.6643	0.7625	1.1672
Cytidine	0.8229	1.0253	0.3316	0.2462	1.2215	2.0174
Cytosine	0.8654	1.0512	0.3394	0.2684	1.2057	1.9589
Glutamate	0.9959	0.9916	1.0087	0.9230	0.9059	1.1036
Glutamine	0.8432	0.9539	1.1288	0.9524	1.0122	1.0440
Glycine	0.9182	1.0152	1.1627	0.8989	1.1057	0.9150
Histamine	0.8912	0.8387	1.6134	0.7750	0.9700	0.8813
Histidine	0.2430	0.4067	2.9750	1.2995	0.3872	0.4292
HomocysteineN	0.9582	1.0108	0.9825	1.0138	0.9743	1.0284
Isoleucine	2.0944	0.4489	0.4744	0.1736	3.7406	0.5775
Leucine	1.0580	0.8573	1.0870	0.4806	1.5501	1.1183
L-Homoserine	0.6812	1.0102	1.1935	1.0289	1.0050	0.9727
Lysine	0.8872	0.9681	1.0819	0.9598	1.0161	1.0396
Methionine	0.5973	0.9480	1.6668	0.9349	0.6503	0.9351
N-acetylglutamine	0.7389	1.1674	1.0435	0.8793	1.0677	0.9957
NG-monomethyl-L-arginine	0.6816	1.1087	1.1628	0.5590	0.8898	1.2949
Ornithine	0.6892	1.3463	0.8275	0.3947	0.6251	1.5929
Phenylalanine	0.7745	1.0982	1.3086	0.7199	0.8639	1.0415
Proline	1.0673	1.0163	1.1496	0.6840	1.0677	1.0194
Propyl-l-carnitine	1.0161	1.0286	0.9377	0.9552	1.0134	1.0407
Purine	0.7895	1.1686	1.2568	0.6889	0.7631	1.0843
Pyridoxine	0.8063	0.8960	1.2162	0.9844	1.0034	1.0267
Serine	0.7697	0.8411	1.3691	0.9410	0.9580	1.0252
Serotonin	0.7596	1.1649	0.5181	0.4092	0.9724	1.7847
Spermine	0.8213	1.4381	1.0584	0.5645	0.6886	1.1089
Threonine	0.6791	1.0523	1.2109	0.9400	1.0021	0.9857
Thyroxine	1.1253	1.1363	0.6422	0.4812	1.4467	1.2407
trans-4-hydroxyproline	1.0279	0.9408	1.0202	1.0331	1.0217	0.9891
Trimethylamine-N-oxide	0.9408	1.3031	0.3644	0.3354	1.1460	1.6575
Tryptophan	0.8029	1.2435	0.9831	0.4440	0.9265	1.3188
Tyrosine	0.7028	1.3773	1.1363	0.5945	0.6577	1.1550
Valine	1.0278	1.0236	0.8248	0.6014	1.2003	1.2839
α-keto-β-methylvaleric-acid	0.8479	1.0993	1.0462	0.9710	0.9613	0.9894
α-keto-δ-NG-NG-dimethylguanidino-valeric-acid	0.7420	2.2681	0.6203	0.3017	0.3528	1.1039
β-aminoisobutyric-acid	0.8434	1.0900	1.1790	0.9400	0.5016	1.1453

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Factors:

F1	Condition:DCM | Gender:F
F2	Condition:DCM | Gender:M
F3	Condition:Donor | Gender:F
F4	Condition:Donor | Gender:M
F5	Condition:ICM | Gender:F
F6	Condition:ICM | Gender:M