Data for Mechanism of Trichloroethylene (TCE) toxicity in the placenta (Study ST001398)
(Analysis AN002338)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this studyMetabolite | F1 | F2 | F3 | F4 |
---|---|---|---|---|
3-Phospho-serine | 1.1451 | 0.8770 | 0.9926 | 0.9853 |
Acetylphosphate | 1.0353 | 0.9383 | 1.0960 | 0.9304 |
Alanine | 1.2386 | 0.8114 | 1.2131 | 0.7370 |
Arginine | 1.0412 | 0.9488 | 1.1662 | 0.8438 |
Asparagine | 1.0718 | 0.9853 | 1.0822 | 0.8606 |
Aspartate | 1.0574 | 0.9462 | 1.0563 | 0.9401 |
Citrulline | 1.0606 | 0.9779 | 1.2005 | 0.7609 |
CMP | 1.2540 | 0.7612 | 1.2253 | 0.7595 |
Creatine | 1.2739 | 0.7983 | 1.2087 | 0.7191 |
Creatinine | 1.0786 | 0.9520 | 1.1474 | 0.8220 |
Deoxyuridine | 1.0221 | 0.7676 | 1.2153 | 0.9950 |
DHAP | 1.2540 | 0.6883 | 1.4622 | 0.5955 |
Gluconate | 1.1450 | 0.8979 | 1.0759 | 0.8812 |
Glutamate | 1.1837 | 0.9203 | 1.0254 | 0.8706 |
Glutamine | 1.0570 | 0.8826 | 1.2191 | 0.8413 |
Glutathione-oxidized | 1.1192 | 0.8172 | 1.1374 | 0.9262 |
Glutathione-Reduced | 1.4138 | 0.9528 | 0.8741 | 0.7594 |
Hexose (glucose etc.) | 0.6303 | 0.5547 | 1.4068 | 1.4082 |
Histidine | 1.3789 | 0.8877 | 1.0147 | 0.7187 |
Homocysteic acid | 1.0021 | 1.1257 | 0.7174 | 1.1549 |
Hypoxanthine | 1.0504 | 0.9507 | 1.0787 | 0.9202 |
IMP | 0.8350 | 0.5334 | 1.7225 | 0.9091 |
Inosine | 0.6183 | 0.2054 | 3.0228 | 0.1534 |
Leucine/isoleucine | 1.1213 | 0.8885 | 1.1613 | 0.8289 |
Lysine | 1.0324 | 0.9395 | 1.2306 | 0.7974 |
Methionine | 1.0707 | 0.8845 | 1.1722 | 0.8726 |
N-Ac-glucosamine-1-P | 1.1339 | 0.7709 | 1.5123 | 0.5828 |
Oleic acid | 1.6240 | 0.4080 | 1.5812 | 0.3868 |
Ornithine | 1.0821 | 0.9673 | 1.1468 | 0.8037 |
Palmitic acid | 1.0055 | 0.8088 | 1.1508 | 1.0349 |
Pantothenate | 1.0117 | 0.9653 | 1.1726 | 0.8505 |
Phenylalanine | 1.0839 | 0.8852 | 1.1588 | 0.8721 |
Phenylpyruvate | 1.1122 | 0.9337 | 1.1082 | 0.8459 |
Phosphocreatine | 0.6635 | 1.1606 | 0.9596 | 1.2163 |
Proline | 1.0560 | 1.0055 | 0.9756 | 0.9628 |
Serine | 1.0921 | 0.7455 | 1.2446 | 0.9177 |
Stearic acid | 1.2603 | 0.9210 | 0.8967 | 0.9220 |
Taurine | 1.2440 | 0.7632 | 1.2396 | 0.7532 |
Threonine | 1.1412 | 0.9627 | 1.0208 | 0.8754 |
Tryptophan | 1.5702 | 0.3823 | 1.6267 | 0.4207 |
Tyrosine | 1.1733 | 0.8567 | 0.9667 | 1.0033 |
UDP | 1.0353 | 1.1048 | 1.0374 | 0.8226 |
UDP-D-glucose | 1.1653 | 0.9048 | 1.0225 | 0.9074 |
UDP-D-glucuronate | 0.4853 | 0.8526 | 1.6943 | 0.9678 |
UDP-N-Ac-D-glucosamine | 1.6997 | 0.7280 | 0.9407 | 0.6317 |
UMP | 1.0889 | 1.1728 | 1.0330 | 0.7053 |
UTP | 0.9505 | 0.8292 | 1.1788 | 1.0415 |
Valine | 1.1902 | 0.9406 | 1.0950 | 0.7742 |
Xanthine | 1.3208 | 0.7096 | 1.1265 | 0.8431 |
Factors:
F1 | Hours of Exposure:12 hr | Treatment:20 uM DCVC |
F2 | Hours of Exposure:12 hr | Treatment:No Treatment |
F3 | Hours of Exposure:6 hr | Treatment:20 uM DCVC |
F4 | Hours of Exposure:6 hr | Treatment:No Treatment |