Data for Changes to gut microbiota metabolism based on Clostridium difficile-induced inflammation (Study ST001650)

(Analysis AN002696)

Values for each metabolite have been scaled by dividing by the mean across all factors

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MetaboliteF1F2F3
1,2-anhydro-myo-inositol NIST 1.0426 1.1855 0.7804
1,5-anhydroglucitol 0.4803 0.5606 1.8552
1-kestose 0.0256 0.0228 2.7567
1-methyladenosine 0.5394 0.9016 1.4669
1-methylinosine NIST 0.9718 1.1039 0.9187
1-monoolein 0.6583 0.8936 1.3798
1-monostearin 1.1570 0.8789 0.9955
2,3-dihydroxybutanoic acid NIST 0.9556 0.8903 1.1452
2,5-dihydroxypyrazine NIST 1.1230 1.2164 0.6852
2,6-diaminopimelic acid 0.6237 1.4143 0.8868
2-aminobutyric acid 0.3390 0.5589 1.9699
2-deoxyerythritol 1.0729 1.1626 0.7790
2^-deoxyguanosine 0.8494 1.0553 1.0652
2-deoxytetronic acid 0.7746 1.1935 0.9868
2-hydroxyglutaric acid 1.1406 1.7913 0.0962
2-hydroxyhexanoic acid 0.8146 1.0731 1.0752
2-hydroxyvaleric acid 0.7624 1.5689 0.6212
2-monoolein 0.7369 0.7355 1.4749
3,4-dihydroxycinnamic acid 1.0491 1.2742 0.6865
3-(4-hydroxyphenyl)propionic acid 0.9396 0.2937 1.7546
3,6-anhydro-D-galactose 0.8505 1.0158 1.1038
3,6-anhydro-D-glucose 0.8947 1.0788 1.0054
3-aminoisobutyric acid 0.8796 1.0381 1.0582
3 hydroxy-3-methylglutaric acid 1.0382 1.1658 0.8036
3-hydroxybutyric acid 0.7209 1.2304 0.9929
3-phenyllactic acid 0.3710 0.5163 1.9869
4-hydroxybenzoate 0.8762 1.2496 0.8495
4-hydroxybutyric acid 0.4287 1.6967 0.7604
4-hydroxyphenylacetic acid 0.3257 1.8304 0.7090
5,6-dihydrouracil 0.9037 1.0750 1.0021
5-aminovaleric acid 1.1591 1.1527 0.7200
5-methoxytryptamine 0.8749 1.0830 1.0171
aconitic acid 0.9910 1.1503 0.8569
adenine 0.9038 1.1523 0.9246
adenosine 1.1236 0.9652 0.9359
adipic acid 1.0504 1.1136 0.8461
alanine 1.1170 0.1896 1.7168
alanine-alanine 0.9250 1.2168 0.8432
allantoic acid 0.3561 0.3420 2.1731
alpha-aminoadipic acid 1.1243 1.0743 0.8263
aminomalonate 0.6994 0.9136 1.3269
arabinose 0.8843 1.3068 0.7858
arabitol 3.3278 0.0521 0.0857
arachidic acid 0.7816 1.2044 0.9704
arachidonic acid 0.6981 1.0777 1.1638
asparagine 1.1094 0.9929 0.9196
aspartic acid 1.0781 1.4410 0.4965
behenic acid 0.7145 1.2005 1.0279
beta-alanine 0.9861 1.1852 0.8259
beta-gentiobiose 0.2581 0.2034 2.3902
beta-glutamic acid 0.5616 1.9101 0.4407
beta-glycerolphosphate 2.0815 0.5414 0.5935
beta-sitosterol 0.8142 1.0043 1.1443
capric acid 1.1229 0.9595 0.9422
cellobiose 0.8189 0.8535 1.2914
cerotinic acid 0.6792 1.1392 1.1175
cholesterol 0.6091 0.9060 1.4067
cis-gondoic acid 0.5134 1.1485 1.2408
citramalic acid 0.8220 1.0851 1.0573
citric acid 1.0940 1.2082 0.7166
citrulline 1.0970 1.2259 0.6966
conduritol-beta-epoxide 1.1882 1.2752 0.5742
creatinine 0.8141 0.8176 1.3311
cysteine 0.9324 1.0207 1.0334
cystine 1.0802 1.0944 0.8415
daidzein 1.0327 1.2284 0.7455
dehydroabietic acid 0.9592 0.9727 1.0599
D-erythro-sphingosine 0.8088 0.9832 1.1698
digalacturonic acid 0.5881 0.4692 1.8602
diglycerol 1.0832 1.1926 0.7409
dihydrocholesterol 0.7262 0.9116 1.3074
enolpyruvate NIST 1.0805 0.8627 1.0729
ethanol phosphate NIST 1.0228 1.6756 0.3062
ferulic acid 1.1235 1.2856 0.6156
fructose 0.3134 0.3977 2.1516
fumaric acid 1.3645 1.2102 0.4982
galactinol 0.0852 0.1210 2.6109
galactonic acid 0.9522 0.8950 1.1433
galacturonic acid 0.9436 1.3379 0.7072
gluconic acid 0.8238 1.0480 1.0929
gluconic acid lactone 0.8253 0.8031 1.3367
glucose 0.8555 0.9528 1.1627
glucose-1-phosphate 0.9957 0.9325 1.0710
glutamic acid 1.1946 1.1632 0.6810
glutamine 0.6023 0.6289 1.6892
glutaric acid 1.2315 1.1939 0.6209
glyceric acid 1.0032 0.9042 1.0933
glycerol 0.7755 0.9310 1.2486
glycerol-3-galactoside 1.0344 1.1076 0.8649
glycerol-alpha-phosphate 0.6074 0.9531 1.3610
glycine 0.8327 0.8222 1.3117
glycolic acid 0.6605 0.8704 1.4012
glycyl-proline 0.7357 1.1201 1.0913
guanine 0.4447 1.9380 0.5062
guanosine 0.7854 0.9523 1.2194
heptadecanoic acid 0.6712 1.0272 1.2358
hexadecylglycerol NIST 0.9019 1.2930 0.7855
hexuronic acid 0.8040 1.1053 1.0515
histidine 0.7769 1.0972 1.0813
homocystine 1.0632 1.4930 0.4564
hydrocinnamic acid 1.2340 0.3179 1.4949
hydroxycarbamate NIST 0.8653 0.8454 1.2623
hypoxanthine 0.5694 2.0431 0.3014
indole-3-acetate 0.1516 1.9437 0.7350
indole-3-lactate 0.9491 1.2320 0.8088
indole-3-propionic acid 0.7985 0.9064 1.2548
indoxyl sulfate 0.7268 1.0657 1.1529
inosine 0.9673 0.9494 1.0768
inositol-4-monophosphate 0.7799 1.9086 0.2675
isocitric acid 0.6586 0.9114 1.3617
isoheptadecanoic acid NIST 0.8820 1.0079 1.0865
isoleucine 0.7420 1.0808 1.1256
isopentadecanoic acid 1.0833 1.3511 0.5823
isothreitol 0.9570 1.3460 0.6884
isothreonic acid 0.9087 0.7143 1.3587
ketohexose 0.8578 0.9801 1.1336
lactic acid 0.7113 0.8257 1.4053
lactitol 0.7198 0.7935 1.4307
lauric acid 1.5270 0.8294 0.7490
leucine 0.7240 1.0571 1.1637
levoglucosan 2.9744 0.1541 0.2663
lignoceric acid 0.8350 1.1180 1.0140
linoleic acid 0.7989 1.0576 1.1032
linolenic acid 0.9344 0.8353 1.2172
lysine 0.7227 1.1273 1.0946
lyxitol 3.3166 0.0540 0.0927
lyxose 0.9641 1.0394 0.9893
maleimide 1.0165 1.2051 0.7817
malic acid 1.9131 1.0300 0.2395
malonic acid 0.9202 1.3031 0.7607
maltitol 0.3599 0.2281 2.2840
maltose 0.2645 0.2876 2.3008
maltotriitol 0.5482 0.5126 1.8488
maltotriose 0.5108 0.4564 1.9349
mannitol 0.9923 0.9313 1.0749
mannonic acid NIST 0.9802 1.4565 0.5593
mannose 0.4484 0.6482 1.7931
melibiose 0.4945 0.4236 1.9808
methanolphosphate 0.7409 0.9514 1.2559
methionine 0.5838 1.5271 0.8058
methionine sulfoxide 0.7003 1.1234 1.1164
methylmalonic acid 0.7585 0.8616 1.3316
methyl O-D-galactopyranoside 0.8464 1.0702 1.0527
monomyristin 0.8627 1.0796 1.0302
montanic acid 0.8689 1.0199 1.0849
mucic acid 1.5067 0.8708 0.7239
myo-inositol 0.9423 1.1081 0.9380
myristic acid 0.7881 0.9267 1.2428
N-acetylaspartic acid 1.7745 1.1861 0.1943
n-acetyl-d-hexosamine 0.8128 1.0708 1.0790
N-acetylmannosamine 1.3742 0.6768 1.0239
N-carbamoylaspartate 1.4141 0.9007 0.7680
nicotinic acid 1.0834 1.4250 0.5083
nonadecanoic acid 0.7179 0.9362 1.2895
oleic acid 1.3207 1.5953 0.1481
ornithine 0.6853 0.9326 1.3192
orotic acid 1.5784 1.3230 0.2143
oxalic acid 0.9687 1.1893 0.8357
oxoproline 1.0220 1.3605 0.6219
palmitic acid 0.7327 1.0100 1.2038
palmitoleic acid 0.8724 0.9529 1.1491
pantothenic acid 0.9518 1.2003 0.8383
parabanic acid NIST 0.9333 1.5292 0.5241
pentadecanoic acid 0.9820 1.1762 0.8383
pentitol 2.6177 0.4431 0.2627
pentonic acid 1.1667 1.3224 0.5442
phenol 0.9212 0.8048 1.2582
phenylacetic acid 0.3357 1.4981 1.0334
phenylalanine 0.6380 1.5101 0.7795
phenylethylamine 0.4725 2.1014 0.3207
phosphate 0.7179 1.6393 0.5864
phosphoethanolamine 1.2853 0.9171 0.8547
p-hydroxylphenyllactic acid 0.6673 1.0760 1.1901
phytol 0.8248 0.9940 1.1462
pimelic acid 0.9066 1.3069 0.7678
pinitol 1.1164 1.2361 0.6708
proline 0.8337 1.2251 0.9079
propane-1,3-diol NIST 0.7465 0.9442 1.2586
pseudo-uridine 0.4569 1.5947 0.8398
p-tolyl glucuronide 0.6996 0.9900 1.2504
putrescine 1.0741 0.6777 1.2630
pyrophosphate 0.9306 0.7130 1.3425
pyruvic acid 0.6592 0.7217 1.5509
quinic acid 0.4928 1.1784 1.2273
quinolinic acid 1.3221 0.8997 0.8426
ribonic acid 1.4814 0.9517 0.6631
ribose 0.9725 1.1471 0.8749
saccharic acid 0.8399 0.8346 1.2935
serine 0.9182 1.0776 0.9878
shikimic acid 0.8164 0.8739 1.2730
sinapinic acid 0.9222 1.0473 1.0149
sorbitol 0.5991 1.5043 0.8164
stearic acid 0.7425 1.0059 1.2001
stigmasterol 0.7352 0.9621 1.2497
succinic acid 2.2677 0.6207 0.3651
sucrose 0.2589 0.9426 1.6503
tagatose 0.5207 0.5323 1.8511
threonic acid 1.1087 0.5821 1.3309
threonine 0.8806 0.9395 1.1560
thymidine 0.9491 1.1256 0.9151
thymine 0.5249 1.8554 0.5247
tocopherol acetate 0.8685 1.0079 1.0973
tocopherol alpha- 0.9675 0.9870 1.0390
tocopherol gamma- 0.9693 0.9546 1.0699
trans-4-hydroxyproline 0.7124 1.2597 0.9704
trehalose 0.5810 0.5260 1.8091
tryptophan 0.7827 0.9412 1.2327
tyrosine 0.6466 1.1183 1.1644
UDP GlcNAc 0.6881 0.6958 1.5537
UDP-glucuronic acid 0.8299 0.6606 1.4755
uracil 0.5182 1.9744 0.4110
urea 0.8263 1.0912 1.0478
uric acid 0.6867 0.8377 1.4129
uridine 0.7883 1.4682 0.7012
urocanic acid 1.1397 1.1216 0.7666
valine 0.7546 0.8865 1.3098
vanillic acid 0.9696 0.9821 1.0422
xanthine 0.6138 1.6637 0.6453
xylitol 3.1856 0.1533 0.0982
xylose 0.6010 1.3127 1.0065
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Factors:

F1Colonization:Ctrl
F2Colonization:Tox-
F3Colonization:WT
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