Data for A cross-sectional study of functional and metabolic changes during aging through the lifespan in male mice (Liver) part-III (Study ST001701)

(Analysis AN002772)

Values for each metabolite have been scaled by dividing by the mean across all factors

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MetaboliteF1F2F3
1,5-anhydroglucitol 1.1855 0.9312 0.9548
1-monopalmitin 1.2141 0.9934 0.8812
1-monostearin 1.1678 0.8301 1.0579
2,5-dihydroxypyrazine NIST 0.9819 1.0156 0.9963
2-hydroxybutanoic acid 0.9274 0.9752 1.0651
2-hydroxyglutaric acid 0.8684 1.0018 1.0751
2-ketobutyric acid 1.0372 1.1031 0.8838
2-monoolein 1.1055 0.8702 1.0574
3-aminoisobutyric acid 0.7746 1.0614 1.0752
3-hydroxybutyric acid 1.2918 0.7978 1.0151
3-phosphoglycerate 0.9089 0.9863 1.0657
4^,5-dihydroxy-7-glucosyloxyflavanone 1.0844 0.8022 1.1321
4-hydroxybutyric acid 1.1215 0.9329 0.9906
4-hydroxyhippuric acid NIST 1.0175 1.0552 0.9391
5-aminovaleric acid 0.5303 1.3479 0.9551
5-methoxytryptamine 1.0107 1.2140 0.7976
adenine 1.0382 0.9984 0.9791
adenosine 1.1198 1.0839 0.8532
adenosine-5-monophosphate 0.9252 0.9073 1.1286
alanine 0.9660 0.9525 1.0633
allantoic acid 0.9875 1.0349 0.9753
alpha-aminoadipic acid 0.7559 0.9130 1.2221
alpha-ketoglutarate 0.9605 0.9218 1.0948
alpha-tocopherol 1.1699 0.9996 0.9013
altrose 1.0716 1.0405 0.9211
aminomalonate 0.6680 1.0338 1.1627
arabitol 0.7696 1.0481 1.0903
arachidic acid 1.0943 0.8217 1.1085
arachidonic acid 1.2189 0.8951 0.9685
ascorbic acid 1.2236 0.7833 1.0682
asparagine 0.8426 1.4045 0.7210
aspartic acid 0.7870 1.2296 0.9138
behenic acid 1.2289 0.9598 0.9033
benzoic acid 0.9858 1.0813 0.9338
beta-alanine 0.6880 1.1137 1.0778
beta-sitosterol 1.0684 0.9608 0.9960
capric acid 0.9883 0.9874 1.0184
cellobiose 1.2951 0.6150 1.1808
cholesterol 0.9999 1.0768 0.9297
cis-gondoic acid 1.2291 0.8721 0.9836
citric acid 1.1241 0.9443 0.9787
creatinine 1.0924 1.0858 0.8674
cyclohexylamine 1.0789 1.0485 0.9095
cysteine 0.6541 1.0724 1.1354
cysteine-glycine 1.1230 1.0692 0.8649
dehydroabietic acid 1.0248 1.0568 0.9335
dehydroascorbic acid 0.8906 1.1391 0.9363
dihydrocholesterol 1.3195 0.8434 0.9572
dihydroxyacetone 1.3808 0.9050 0.8650
docosahexaenoic acid 1.1534 0.8830 1.0178
ethanolamine 0.7133 1.1445 1.0348
fructose 1.2294 0.6219 1.2128
fructose-1-phosphate 0.8282 1.1688 0.9455
fructose-6-phosphate 0.8648 1.2163 0.8806
fumaric acid 0.7933 1.1036 1.0256
galactonic acid 1.1631 0.8302 1.0605
galactose-6-phosphate 0.9170 1.1731 0.8898
gluconic acid 1.0529 0.8694 1.0888
glucose 1.0341 0.9337 1.0409
glucose-1-phosphate 0.9444 1.1504 0.8946
glucose-6-phosphate 0.8632 1.2335 0.8657
glutamic acid 0.8918 1.0589 1.0091
glutamine 1.1068 1.2583 0.7009
glutaric acid 0.8935 1.6188 0.4949
glutathione 0.9856 1.1612 0.8607
glycerol 1.0962 0.8920 1.0429
glycerol-3-galactoside 1.3693 0.8336 0.9371
glycerol-alpha-phosphate 0.6532 1.1758 1.0411
glycine 0.8949 1.1117 0.9590
glycolic acid 0.9048 1.0139 1.0428
glycyl-proline 1.2114 0.8536 1.0109
guanosine 1.3767 0.8167 0.9483
heptadecanoic acid 1.0089 0.9647 1.0272
hexitol 1.2207 0.9295 0.9358
hexose-6-phosphate 0.6446 1.4113 0.8303
hexuronic acid 1.0257 0.7695 1.1963
histidine 0.9339 0.9499 1.0845
homoserine 1.4820 0.5516 1.1299
hydroxylamine 1.1382 0.8830 1.0266
hypoxanthine 1.0881 0.9885 0.9592
inosine 1.1659 0.9079 0.9877
inosine 5^-monophosphate 0.8060 1.2028 0.9273
inositol-4-monophosphate 0.9828 1.3605 0.6795
isohexonic acid 0.8406 0.8651 1.2166
isoleucine 0.9393 1.0841 0.9583
isomaltose 1.1939 0.8001 1.0701
isothreitol 1.9054 0.3905 1.0305
isoxylonic acid 1.5371 0.8004 0.8697
lactamide 0.9441 1.0148 1.0190
lactic acid 0.9787 0.9345 1.0725
lactitol 1.3555 0.6704 1.0947
lactose 1.2574 0.7850 1.0469
lauric acid 0.9554 0.9038 1.1142
leucine 0.8939 1.0733 0.9947
levoglucosan 1.0455 1.0132 0.9613
linoleic acid 1.0406 0.8524 1.1116
linolenic acid 1.0739 1.0334 0.9263
lysine 0.8491 1.0472 1.0448
lyxose 1.0642 1.0437 0.9225
maleimide 0.8378 1.3829 0.7436
malic acid 0.7675 1.0816 1.0608
maltose 1.1544 0.8012 1.0922
maltotriose 1.0974 0.8189 1.1092
mannose 0.9800 0.8773 1.1242
melezitose 1.0968 0.7830 1.1425
methanolphosphate 1.0041 1.0912 0.9140
methionine 0.9115 1.1069 0.9536
myo-inositol 0.7725 1.3267 0.8333
myristic acid 1.0127 0.9845 1.0068
N-acetyl-aspartic acid 1.1904 1.0611 0.8329
N-acetyl-D-galactosamine 1.2312 0.8340 1.0173
n-acetyl-d-hexosamine 1.2006 0.6970 1.1608
N-acetyl-D-mannosamine 0.8491 1.3372 0.7789
n-acetylglutamate 1.1757 0.9611 0.9331
N-acetylmannosamine 1.1973 0.8693 1.0047
nicotinamide 1.0158 0.9161 1.0677
N-methylalanine 0.7926 0.8513 1.2573
octadecanol 0.9769 1.0864 0.9342
oleamide NIST 0.8536 0.9141 1.1642
oleic acid 1.3284 0.8697 0.9279
ornithine 0.8246 1.2456 0.8772
orotic acid 1.2735 0.9918 0.8480
oxalic acid 0.9981 1.0220 0.9810
oxoproline 0.9579 1.1542 0.8832
palmitic acid 1.0782 0.9598 0.9913
palmitoleic acid 1.2254 0.8102 1.0426
pantothenic acid 1.0906 0.8252 1.1074
parabanic acid NIST 0.9589 0.9605 1.0602
pelargonic acid 0.9424 1.0239 1.0117
phenylalanine 0.9712 1.1100 0.9160
phenylethylamine 0.9519 0.9285 1.0936
phosphate 0.9882 0.9974 1.0092
phosphoethanolamine 0.5053 1.8014 0.5539
phosphogluconic acid 0.9299 1.2991 0.7667
phthalic acid 0.6159 0.7680 1.4367
pipecolinic acid 0.7622 1.1454 1.0055
proline 0.9018 1.0150 1.0435
propoxycarbonylglycine, ethyl ester NIST 0.8179 1.0406 1.0690
pyrophosphate 0.9115 0.9784 1.0714
pyruvic acid 0.9341 0.7306 1.2854
raffinose 1.2792 0.8155 1.0063
ribitol 1.2970 0.6725 1.1270
ribonic acid 1.5970 0.6807 0.9444
ribose 1.1489 0.7982 1.0981
ribose-5-phosphate 0.8749 1.0561 1.0215
ribulose-5-phosphate 0.7127 1.4505 0.7547
serine 1.0246 1.1078 0.8869
shikimic acid 0.8297 1.2081 0.9086
sophorose 1.2104 0.7905 1.0693
sorbitol 1.1249 0.6836 1.2172
spermidine 1.6332 0.8969 0.7252
squalene 0.8997 0.9061 1.1446
stearic acid 0.9548 0.9104 1.1085
succinate semialdehyde 1.4015 1.4416 0.3610
succinic acid 0.8246 1.3105 0.8177
sucrose 1.2185 1.7762 0.1610
sulfuric acid 1.3127 1.1809 0.6518
taurine 0.5472 1.4559 0.8462
threonic acid 1.0001 1.1640 0.8496
threonine 0.9381 1.0978 0.9465
trans-4-hydroxyproline 0.9530 0.9045 1.1149
trehalose 1.2671 0.7149 1.1056
tryptophan 1.0379 1.0513 0.9308
tyrosine 1.0335 1.1072 0.8822
UDP-glucuronic acid 1.1610 0.9032 0.9948
UDP-N-acetylglucosamine 0.9930 0.9988 1.0052
uracil 0.9161 1.0379 1.0142
urea 0.8988 1.1193 0.9497
uric acid 0.9659 1.1046 0.9240
uridine 1.1494 0.8587 1.0424
valine 0.9012 1.0467 1.0148
xanthine 1.0612 0.9684 0.9933
xanthosine 1.0568 0.8068 1.1440
xylitol 1.0576 0.7987 1.1510
xylonolactone NIST 1.0826 0.9905 0.9606
xylose 0.9227 1.1981 0.8635
xylulose NIST 1.0284 0.9093 1.0666
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Factors:

F1Age:mid age
F2Age:old
F3Age:young
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