Data for Mitochondrial ATP fuels ABC transporter-mediated drug efflux in cancer chemoresistance (Study ST001730)

(Analysis AN002816)

Values for each metabolite have been scaled by dividing by the mean across all factors

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MetaboliteF1F2
13(S)-HODE 1.0617 0.9383
2/3-Phospho-D-glycerate 0.9189 1.0811
2-Deoxy-alpha-D-glucoside 1.4188 0.5812
2-Hydroxyglutarate/Citramalate 0.8341 1.1659
2-Methyleneglutarate 1.2590 0.7410
2-Oxo-7-methylthioheptanoic acid 0.9310 1.0690
2-Oxoglutaramate 0.9441 1.0559
2-Oxoglutarate 0.7303 1.2697
3-Oxalomalate 0.8579 1.1421
5-6-Dihydrothymine 0.9561 1.0439
5-Hydroxyisourate 0.7121 1.2879
5-Oxoproline 0.8457 1.1543
9-Oxononanoic acid 1.0633 0.9367
Acetylcholine 0.8411 1.1589
Adenine 1.4340 0.5660
Adenosine 1.0463 0.9537
ADP 1.6236 0.3764
Adrenic acid (7,10,13,16-Docosatetraenoic acid) 0.5897 1.4103
a-Linolenic acid (Octadecatrienoic acid) 1.1680 0.8320
alpha-D-Ribose 1-phosphate 0.9298 1.0702
Arachidonic acid (Eicosatetraenoic acid) 1.1419 0.8581
Argininosuccinate 0.9305 1.0695
Ascorbate 1.4406 0.5594
Carnosine 1.0585 0.9415
Catechin 0.5124 1.4876
CDP 1.1929 0.8071
CDP-choline 1.3199 0.6801
Cholesterol sulfate 0.7889 1.2111
Citrate 1.1484 0.8516
CMP 1.6618 0.3382
CMP-N-acetylneuraminate 1.0125 0.9875
CTP 0.8232 1.1768
Cytidine 1.2486 0.7514
D-Arabitol 1.4467 0.5533
Decanoic acid (capric acid) 1.2442 0.7558
Dehydroascorbate 0.9058 1.0942
D-Erythrose 4-phosphate 0.9308 1.0692
D-Fructose 1-6-bisphosphate 1.0826 0.9174
D-glucono-1,5-lactone 1.0672 0.9328
D-Glucose 1.1335 0.8665
D-Glucose 6-phosphate 1.0830 0.9170
D-Glyceraldehyde 3-phosphate/Glycerone phosphate 0.9818 1.0182
Dihomo-gamma-linolenic acid ((8Z-11Z-14Z)-Icosatrienoic acid) 1.1326 0.8674
Diphosphate 0.8741 1.1259
Docosahexaenoic acid 1.0261 0.9739
Docosapentaenoic acid ((7Z-10Z-13Z-16Z-19Z)-Docosa-7-10-13-16-19-pentaenoic acid) 0.5864 1.4136
Dodecanoic acid (lauric acid) 1.2789 0.7211
D-Ribose 5-diphosphate 0.9476 1.0524
Eicosapentaenoic acid 0.9793 1.0207
Ethanolamine phosphate 0.6006 1.3994
Fumarate 0.8707 1.1293
gamma-L-Glutamyl-L-cysteine 1.1004 0.8996
Glucosinolate 1.2370 0.7630
Glycerol 3-phosphate 0.8207 1.1793
Glycochenodeoxycholate 0.8856 1.1144
Guanosine 0.3352 1.6648
Heptanoic acid 0.9063 1.0937
Hexadecanoic acid (palmitic acid) 1.1016 0.8984
Hexadecenoic acid (Palmitoleic acid) 1.2728 0.7272
Hexanoic acid (caproate) 1.0233 0.9767
Hypoxanthine 0.8568 1.1432
Inosine 0.8065 1.1935
Lactate 0.8827 1.1173
Leucocyanidin 1.2116 0.7884
Leukotriene A4 1.3058 0.6942
Linoleic acid ((9Z,12Z)-Octadecadienoic acid) 1.0420 0.9580
L-Noradrenaline 1.0872 0.9128
Malate 0.8119 1.1881
Maltose 1.1355 0.8645
Mannitol 1.1371 0.8629
Methylenediurea 1.0906 0.9094
N6-Methyl-L-lysine 0.9670 1.0330
N-Acetylmethionine 1.3539 0.6461
N-Acetylneuraminate 1.1513 0.8487
N-Acyl-D-mannosaminolactone 1.4063 0.5937
Nonanoic acid (pelargonic acid) 1.1869 0.8131
N-Succinyl-L-citrulline 0.4073 1.5927
Octadecanoic acid (stearic acid) 1.0491 0.9509
Octadecenoic acid (Oleic acid) 1.1260 0.8740
Octanoic acid (caprylic acid) 0.9274 1.0726
Pantothenol 0.6712 1.3288
Pentanoate (valerate) 0.8987 1.1013
Phosphocreatine 0.4839 1.5161
Prostaglandin A2 1.0821 0.9179
Prostaglandin D2/Thromboxane A2 (isobars) 1.1667 0.8333
Pyruvate 0.9047 1.0953
Riboflavin 0.8020 1.1980
S-Acylglutathione 1.0776 0.9224
S-Adenosyl-L-homocysteine 0.9855 1.0145
Sedoheptulose 1-phosphate 1.0990 0.9010
S-Glutathionyl-L-cysteine 1.0562 0.9438
Shikimate 3-phosphate 1.0134 0.9866
Sphinganine 1-phosphate 1.0647 0.9353
Sphingosine 0.8434 1.1566
Stearidonic acid ((6Z,9Z,12Z,15Z)-Octadecatetraenoic acid) 0.7931 1.2069
Succinate 1.2080 0.7920
Taurodeoxycholate/taurochenodeoxycholate/tauroursodeoxycholate 0.9222 1.0778
Tetradecanoic acid (myristic acid) 1.2805 0.7195
Tetradecenoic acid (myristoleic acid) 1.2931 0.7069
Thiocysteine 0.9522 1.0478
Thymidine 1.1195 0.8805
Thymine 1.0023 0.9977
trans-4-Hydroxy-L-proline 1.1298 0.8702
UDP 1.7373 0.2627
UDP-glucose 1.2255 0.7745
UDP-N-acetyl-D-glucosamine 1.1863 0.8137
UMP 1.9245 0.0755
Undecanoic acid 1.1835 0.8165
UTP 1.5784 0.4216
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Factors:

F1line:NCI-ADR-RES
F2line:OVCAR8
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