Data for Timecourse of NIH-3T3 cells treated with apoptotic inducers (Study ST001740)

(Analysis AN002833)

Values for each metabolite have been scaled by dividing by the mean across all factors

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MetaboliteF1F2F3F4F5F6F7F8F9F10F11F12F13F14F15F16F17F18F19F20F21F22F23F24F25F26F27F28F29F30F31F32F33F34F35F36F37F38F39F40F41F42F43F44F45
Phosphatidylinositol(16:0/18:1) 0.3923 0.4624 0.3422 0.2588 0.5919 0.7359 1.5584 0.6021 0.4870 0.3027 0.4554 0.4271 0.3107 0.3090 1.2525 1.5565 0.8055 0.5545 0.5005 0.7505 1.2763 0.3941 0.4322 1.1134 1.8923 4.7662 0.7896 0.8296 1.6058 1.6577 0.3806 0.5679 2.0642 1.4788 3.3546 1.6040 0.4461 0.3890 0.7289 0.6688 0.4818 0.7344 1.9141 3.4900 0.4242
Phosphatidylinositol(16:0/20:3 n-6) 0.8883 1.0425 0.9397 0.8639 0.7811 0.7920 0.8617 0.7840 0.7481 0.8420 0.7366 0.7165 0.7322 0.5390 0.9871 1.2683 0.9966 0.7827 0.6133 0.8555 1.6985 0.5831 0.7063 0.9153 1.7168 2.7221 0.8584 0.6232 1.5676 1.4426 0.3942 0.4923 1.0881 1.2303 2.7531 0.8135 0.6359 0.7322 1.0119 0.7344 0.7964 1.0520 1.6446 2.2794 0.7670
Phosphatidylinositol(16:0/20:4) 1.0841 1.0446 1.0300 1.1608 1.0471 0.9555 1.1777 1.1605 1.0990 0.8947 1.0219 1.1191 1.0676 1.0087 0.8384 1.1127 1.1453 1.0867 0.6518 1.0263 0.8298 0.7512 1.1138 1.0113 0.8396 0.8213 1.0531 0.7379 1.1485 0.8511 0.6007 1.1716 0.9598 0.7546 0.9569 1.0064 0.9809 1.1081 1.0568 0.8652 1.1077 1.0451 0.8952 1.1132 1.1211
Phosphatidylinositol(16:1/18:1) 0.5474 0.5195 0.5399 0.4720 0.8578 1.0314 1.8595 0.6259 0.6972 0.4775 0.6051 0.5214 0.5541 0.5673 1.3801 1.8514 0.5984 0.6607 0.5368 0.9867 1.4569 0.7129 0.4713 1.2988 1.8170 1.7073 1.1554 0.5775 1.3026 1.6961 0.7985 0.7196 2.5675 0.9828 1.0112 2.2421 0.5802 0.5401 1.1231 0.6475 0.5199 1.0797 1.6724 1.4735 0.6001
Phosphatidylinositol(18:0/20:3 n-6) 0.6945 0.8475 0.7774 0.7141 0.8006 0.8672 0.7024 0.7767 0.8169 0.7259 0.8288 0.7953 0.8220 0.8632 0.9365 0.7735 0.9713 0.7792 0.8778 0.8542 1.4407 0.9661 0.7802 0.8411 1.6630 2.2255 0.9015 1.1710 1.1162 1.5613 0.8596 0.6684 0.7631 2.1247 2.3407 0.9081 0.7406 0.7589 1.0438 0.9033 0.8509 0.9261 1.2756 1.8170 0.8612
Phosphatidylinositol(18:0/20:4) 1.1237 1.0907 1.1223 1.1236 1.0401 0.9982 0.7845 1.0633 1.0732 1.1745 1.1294 1.1068 1.1511 1.1448 0.8758 0.7368 1.0982 1.0971 1.3190 1.0098 0.7979 1.2703 1.2199 0.8230 0.7122 0.4236 0.9551 1.2546 0.9330 0.7458 1.3078 1.2571 0.6435 0.8239 0.6171 0.7881 1.1726 1.1500 0.9515 1.1847 1.2253 0.9392 0.6917 0.7466 1.0945
Phosphatidylinositol(18:0/22:5) 0.7773 0.8573 0.8554 0.7608 0.7462 0.9283 0.7918 0.7954 0.8275 0.8010 0.8023 0.7956 0.7820 0.7597 1.2277 0.8998 1.0126 0.6955 0.7228 0.8678 1.3352 0.7911 0.8134 0.7084 1.5052 3.7925 0.7087 0.8731 0.9849 1.2440 0.6926 0.7662 0.5930 1.8756 2.8611 0.6201 0.7450 0.8249 0.8471 0.9858 0.7773 1.0752 1.1840 2.1561 0.8407
Phosphatidylinositol(18:0/22:6) 0.7156 0.9499 0.6827 0.6165 0.7342 0.9170 0.9011 0.8378 0.7505 0.7999 0.7983 0.9266 0.6968 0.7969 1.3247 0.9761 1.0874 0.6889 0.5752 0.7940 1.7006 0.7143 0.7305 0.8990 1.3547 4.9791 0.7582 0.6210 0.9111 1.2981 0.3880 0.5196 0.6275 1.4017 3.5602 0.6460 0.5464 0.5511 0.9661 0.9383 0.7262 0.9197 1.1551 2.1213 0.7763
Phosphatidylinositol(18:1/18:1) 0.6152 0.6792 0.5571 0.5607 0.8702 1.0732 1.6372 0.7120 0.7694 0.5990 0.6393 0.6542 0.4975 0.5913 1.7104 1.7881 0.7291 0.7930 0.4816 0.9763 1.2277 0.4736 0.5190 1.6096 1.7730 1.3609 1.1704 0.6538 1.2234 1.3128 0.4676 0.4997 2.6778 1.2184 1.0311 2.0962 0.5486 0.6460 0.9384 0.6008 0.4744 1.1642 2.0210 1.1564 0.6862
Phosphatidylinositol(18:1/20:3 n-6) 1.0460 1.0243 0.8912 0.8184 1.1957 0.9495 1.2880 1.0011 1.0346 0.9897 0.8443 0.9534 0.8107 0.9533 1.0683 1.2513 0.8412 1.0043 0.7882 1.1140 1.5316 0.6044 0.5743 1.3288 1.3006 0.8931 1.1239 0.7480 0.9481 1.8558 0.6876 0.5229 1.2282 1.2017 0.8869 0.9965 0.8245 0.8300 1.2234 0.6008 0.6224 1.1698 1.6533 0.6105 1.0033
Phosphatidylinositol(18:1/20:4) 1.1731 1.1252 1.2287 1.2559 1.1689 1.1442 1.2338 1.2072 1.1493 1.0737 1.0850 1.1265 1.1575 1.1096 0.9233 1.2717 0.8787 1.0975 0.7430 1.1580 1.0600 0.8193 0.9339 1.2813 0.7567 0.3328 1.1905 0.5592 0.8286 1.0434 0.8169 0.8357 0.9997 0.5819 0.4563 0.9559 1.1098 1.0900 1.1972 0.8836 0.9011 1.1413 0.9044 0.3619 1.1273
Phosphatidylinositol(18:1/20:5) 1.1466 1.2593 1.0949 1.2508 1.3120 1.0823 1.4969 1.3011 1.1006 1.1157 1.1041 1.2153 1.1866 1.0637 1.2106 1.4525 1.0353 1.1749 0.4370 0.8760 1.0522 0.6849 0.7467 1.2535 0.8086 0.3372 1.1092 0.5013 0.7710 1.0229 0.8813 0.7170 1.1080 0.5766 0.2103 1.0204 1.0738 1.0710 1.2615 0.8562 0.7888 1.2337 1.1498 0.3641 1.0393
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Factors:

F1hours:0.17 | treatment:CHX | concentration:20 µg/ml
F2hours:0.17 | treatment:ETO | concentration:10 µM
F3hours:0.17 | treatment:MC | concentration:10 µM
F4hours:0.17 | treatment:Serum | concentration:-
F5hours:0.17 | treatment:STS | concentration:0.3 µM
F6hours:0.17 | treatment:TNFα | concentration:10 ng/ml
F7hours:0.17 | treatment:TPG | concentration:2 µM
F8hours:0.17 | treatment:VAL | concentration:10 µM
F9hours:0.17 | treatment:vehicle (DMSO) | concentration:-
F10hours:1 | treatment:CHX | concentration:20 µg/ml
F11hours:1 | treatment:ETO | concentration:10 µM
F12hours:1 | treatment:MC | concentration:10 µM
F13hours:1 | treatment:Serum | concentration:-
F14hours:1 | treatment:STS | concentration:0.3 µM
F15hours:1 | treatment:TNFα | concentration:10 ng/ml
F16hours:1 | treatment:TPG | concentration:2 µM
F17hours:1 | treatment:VAL | concentration:10 µM
F18hours:1 | treatment:vehicle (DMSO) | concentration:-
F19hours:24 | treatment:CHX | concentration:20 µg/ml
F20hours:24 | treatment:ETO | concentration:10 µM
F21hours:24 | treatment:MC | concentration:10 µM
F22hours:24 | treatment:Serum | concentration:-
F23hours:24 | treatment:STS | concentration:0.3 µM
F24hours:24 | treatment:TNFα | concentration:10 ng/ml
F25hours:24 | treatment:TPG | concentration:2 µM
F26hours:24 | treatment:VAL | concentration:10 µM
F27hours:24 | treatment:vehicle (DMSO) | concentration:-
F28hours:48 | treatment:CHX | concentration:20 µg/ml
F29hours:48 | treatment:ETO | concentration:10 µM
F30hours:48 | treatment:MC | concentration:10 µM
F31hours:48 | treatment:Serum | concentration:-
F32hours:48 | treatment:STS | concentration:0.3 µM
F33hours:48 | treatment:TNFα | concentration:10 ng/ml
F34hours:48 | treatment:TPG | concentration:2 µM
F35hours:48 | treatment:VAL | concentration:10 µM
F36hours:48 | treatment:vehicle (DMSO) | concentration:-
F37hours:6 | treatment:CHX | concentration:20 µg/ml
F38hours:6 | treatment:ETO | concentration:10 µM
F39hours:6 | treatment:MC | concentration:10 µM
F40hours:6 | treatment:Serum | concentration:-
F41hours:6 | treatment:STS | concentration:0.3 µM
F42hours:6 | treatment:TNFα | concentration:10 ng/ml
F43hours:6 | treatment:TPG | concentration:2 µM
F44hours:6 | treatment:VAL | concentration:10 µM
F45hours:6 | treatment:vehicle (DMSO) | concentration:-
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