Metabolite_name RefMet_name A1 A10 A11 A3 A6 C1 C2 C3 C4 C5 T10 T11 T2 T4 T5 Factors - hibernation:arousal hibernation:arousal hibernation:arousal hibernation:arousal hibernation:arousal hibernation:control hibernation:control hibernation:control hibernation:control hibernation:control hibernation:torpor hibernation:torpor hibernation:torpor hibernation:torpor hibernation:torpor 11-Octadecenoic acid trans-Vaccenic acid 102426 73893 132079 81849 63751 68024 58099 40820 59899 63284 73882 98453 119366 84304 69665 1-methyl nicotinamide 1-Methyl nicotinamide 16917 13320 16270 14118 17571 20748 19029 12173 14153 20517 12465 12569 16261 13111 12462 1-Monopalmitin MG 16:0/0:0/0:0 704463 754258 800502 858048 784605 853109 770089 396575 693589 873365 683381 864009 1225253 891868 663665 2-((2-Chloroethyl)ethylamino)ethanol 2139 1867 2657 2006 2195 2532 2429 1977 2705 2623 2492 2414 2931 3120 2013 2_3-Butanediol 2,3-Butanediol 1445434 1006372 930561 1288442 1335528 1309226 1301448 895690 963886 1313704 506363 649081 1123052 590058 606190 2_3-dihydroxypyridine 2,3-Dihydroxypyridine 1415 1338 999 1291 1754 1203 1185 1105 1087 1882 1551 1256 1720 1775 973 2_4_6-trimethyl-Pyridine 2,4,6-Trimethylpyridine 43452 40890 40591 41538 42365 38512 43092 42763 39342 42189 42508 43239 44462 36261 42031 2-Butanol 259640 183921 166610 237020 246692 238326 237212 162648 176575 240117 96543 119694 209007 112481 108923 2-Butenedioic acid Fumaric acid 936 1559 871 1490 1285 1200 1412 1820 684 1352 1702 1661 1744 1146 1039 2-hydroxypyridine 2-Hydroxypyridine 25174 47070 30228 29534 39888 30217 34636 24163 32967 29980 26926 26536 42778 25114 26815 2-Keto-l-gluconic acid 3594 3323 2847 2855 2673 3521 3959 3048 3683 4543 3087 2730 2179 2675 2266 2-Palmitoylglycerol MG 0:0/16:0/0:0 10658 10767 11659 11365 9532 12107 9604 5325 10156 11551 9567 12708 15289 13700 9748 2-Pyrrolidinone 2-Pyrrolidinone 28663 29884 32897 31930 33151 29511 25074 21090 21506 29440 24468 30051 30998 27076 24448 3_5-Dihydroxy-2H-1_2_4-oxadiazine 1329 1832 1409 2658 2101 1547 1507 960 1133 1951 4144 1845 4345 4446 3957 3-Aminodihydro-2(3H)-furanone 50196 34596 23684 36497 25330 33415 55687 51297 29292 49386 34439 60472 56863 40891 49849 3-Heptanol 6715 7576 7041 6775 8130 6104 6908 6988 7521 6349 7651 6090 7527 6741 5961 3-hydroxy-3-methylglutaric acid (dicrotalic acid) 3-Hydroxymethylglutaric acid 921 750 1408 1129 1413 944 744 543 850 830 694 816 1392 708 963 3-hydroxypyridine 3-Hydroxypyridine 3051 5148 4063 4168 4001 3034 3996 3058 4181 3796 4051 3432 4698 2964 3425 3-methyl-2-oxobutanoic acid Ketoisovaleric acid 26403 28395 30232 29873 26818 28699 29136 30015 27600 31074 28898 29236 25806 27870 29240 4-Aminobutanoic acid gamma-Aminobutyric acid 194047 195261 186750 215919 191350 181985 172899 149448 87463 189448 144040 207355 191957 170590 160000 4-guanidinobutyric acid 4-Guanidinobutanoic acid 286784 265653 368820 298277 279164 312889 249767 188761 229205 281415 211115 272823 323696 292731 234467 Acetamide Acetamide 15649 13961 19638 16296 16741 15620 13637 8245 9053 14171 14592 18261 20183 17419 14050 acetoacetate Acetoacetic acid 12031 13190 12074 13041 12957 11224 15228 12728 13164 13030 14459 13971 14574 11716 14464 adenosine Adenosine 18517 13939 13560 17676 11963 36717 27669 31995 29786 9879 20017 27656 18621 12254 11690 allo-inositol 8385 9854 15034 10504 9031 8454 5858 6609 7216 11545 14840 17304 10753 12792 11250 Allyl(methoxy)dimethylsilane 39989 38642 38813 40085 38616 38651 41763 39605 40815 42917 40851 38819 36630 36485 41309 Aminomalonic acid Aminomalonic acid 13576 13190 14726 12159 16696 13367 13340 9582 13104 10604 12930 13931 17825 13265 11251 Arabino-Hexos-2-ulose_ 3_4_5_6-tetrakis-O-(trimethylsilyl)-_ bis(dimethyl acetal) 2487 1908 4065 3803 2132 3908 1818 1063 2205 3010 2638 3097 2553 3065 2381 arachidic acid Arachidic acid 4977 4938 5424 3431 4530 3089 3323 3015 3591 4533 4714 5594 6006 4302 3677 Arachidonic acid Arachidonic acid 57099 46856 80685 53364 41211 41702 29388 20873 32723 43266 48936 61325 72081 60545 38226 aspartic acid Aspartic acid 1511833 1484797 1863299 1753344 1569120 2153100 1981558 1398800 1579220 2171636 1530146 1787837 1963995 1760457 1556621 benzoic acid Benzoic acid 5244 4605 4901 5978 6679 5522 4384 3480 3695 4401 4030 4390 4480 4962 4479 Beta-alanine beta-Alanine 15792 16539 19389 19551 17318 18553 18654 13211 17373 17570 14877 17254 20332 18175 13497 beta-L-(-)-Fucopyranose 2504 2053 3660 2656 2666 3083 3419 1648 2348 4163 2933 4420 3219 3181 2768 Boric acid 120352 90321 127743 75787 151227 121834 86392 66135 531769 80425 139700 63193 70048 48973 51839 caprylic acid Caprylic acid 434888 386260 505802 425759 395316 479590 416211 279031 386150 466200 392394 456482 526161 416241 349831 cholesterol Cholesterol 4788534 4855876 5618771 4239004 4644198 5419422 5537861 3623128 4672047 5320610 4639449 5611276 6215100 4800965 4281722 citric acid Citric acid 24170 26958 34569 43553 31311 21723 19113 14858 13764 17009 37358 42087 39397 42018 45012 Creatinine Creatinine 662896 570326 794378 690690 557080 856308 703580 565256 552541 807877 735012 740628 750989 657553 626310 D-allose 1 Allose 38804 36994 55037 46302 35754 40038 26665 24511 26455 43500 59495 55086 39075 58596 41525 D (+)altrose 179781 177526 270309 253253 158998 119114 110661 86212 86248 163824 444073 398945 352302 478703 353576 D-(+)-Arabitol Arabitol 1811 1043 2835 1034 1415 1409 1925 1375 1319 1039 1908 868 2617 1600 1920 D-galactose Galactose 179684 177308 270309 251737 158909 109479 107716 82373 86291 160175 444073 399200 352551 469580 353576 D-Glucopyranose Glucose 33996 34026 58225 46801 21796 9805 16867 10149 15755 9111 42072 33576 113584 16264 37501 D-glucose-6-phosphate Glucose 6-phosphate 108539 122080 131207 108630 153125 204689 126128 80921 80256 77663 166284 196450 216939 85987 211422 dihydroxyacetone phosphate Dihydroxyacetone phosphate 1867 1901 2282 1871 1319 1839 1820 712 1272 1857 1999 2144 2968 1775 1121 DL-isoleucine Isoleucine 31653 26745 26879 28315 29737 33340 32903 20285 23471 32726 24839 26579 32760 24160 20821 D-malic acid D-Malic acid 26742 25926 32882 26478 26484 41823 35991 26842 31072 45857 22362 27376 33296 27671 22672 D-mannitol Mannitol 6528 5387 6701 5877 7608 5977 5413 3340 3541 4663 6560 5730 8395 7332 5753 D-Mannose_ 2_3_4_5-tetrakis-O-(trimethylsilyl)-_ O-methyloxime_ 6-[bis(trimethylsilyl) phosphate] Mannose 39004 47045 74205 50539 42048 44443 29136 27049 28250 47043 68279 78181 37842 56613 58552 D-Ribose_ 2_3_4-tris-O-(trimethylsilyl)-_ O-methyloxime_ 5-[bis(trimethylsilyl) phosphate] Ribose 36229 37608 65657 46322 36128 41987 28016 26422 31867 36222 58405 69666 35721 74938 46485 D-threitol Threitol 2717 2468 3224 3298 3143 1794 1983 997 1360 1460 2390 2717 3937 2700 3106 Ethanolamine Ethanolamine 319033 173690 377617 267965 238646 302871 201802 127062 247689 288008 220394 287600 387132 254450 193384 fructose Fructose 20676 18365 25370 26189 21831 23353 18527 14779 18265 29582 28328 28796 27465 28530 25889 fumaric acid Fumaric acid 59398 58176 71953 67037 64227 95299 82537 58280 67388 105658 47726 58565 72208 57979 48113 glucoheptonic acid Glucoheptonic acid 2383 2282 1714 1865 1063 2451 1370 892 1526 3190 2225 3102 2698 3022 2748 glyceric acid Glyceric acid 10814 9150 12791 12565 11270 12247 10015 7022 9958 13315 10197 11941 23485 12613 10207 glycerol Glycerol 737374 496482 807767 629061 533483 615524 453960 318046 490904 611723 589610 693622 762682 570372 459252 glycerol 1-phosphate sn-Glycero-3-phosphate 7542 5977 10603 8983 7158 8151 5428 4676 5536 6824 7830 9701 10979 8373 7305 glycine Glycine 288941 391919 427957 396444 407111 410183 272166 166084 320144 355166 370596 328447 395943 322580 248150 glycolic acid Glycolic acid 25304 14561 23869 22631 14877 20977 13029 10852 18669 17183 19396 21150 30485 27365 16920 heptadecanoic acid Margaric acid 4117 3353 5230 3565 4275 3707 3317 2831 3724 4770 3969 4143 4783 3421 3654 Heptan-4-ol Heptan-4-ol 11708 10491 9849 10819 13255 11875 10314 9415 10300 10247 10152 10715 10739 8819 11006 Hydroxylamine Hydroxylamine 5829 7277 6097 6046 6158 5962 6460 6691 4888 5460 6563 5636 6869 5052 6383 hypotaurine Hypotaurine 2700 2513 3204 3821 3108 2898 3086 1621 1984 3045 2789 2239 3698 3698 3094 hypoxanthine Hypoxanthine 247339 277249 297261 302052 266375 340599 286215 215615 247248 320561 246578 295876 353776 282896 246789 inosine Inosine 16526 19257 19172 20652 16936 30084 26521 18502 20362 27714 16111 18465 20810 16195 15160 lactamide Lactamide 2349 1420 1489 1852 2682 2094 2117 1513 1398 2704 1038 1524 1675 1271 1186 L-alanine Alanine 314281 350077 468633 496947 383046 322153 280325 174681 183754 322518 374107 492400 514708 434060 341889 L-asparagine Asparagine 4518 3884 4395 4848 4559 6338 5622 4086 4292 6008 4191 4523 4741 4194 3745 L-glutamic acid Glutamic acid 821593 893194 1183238 1057162 879954 1385264 1227136 873271 1007810 1416477 1112794 1167970 1193734 1048754 996729 L-glutamine Glutamine 12678 8097 16403 12878 13072 12886 7712 6990 6165 12498 8874 11440 10595 10017 7880 L-histidine Histidine 720 882 1312 818 1253 883 405 167 388 649 860 1536 1081 1001 551 L-lactic acid Lactic acid 328621 236131 213153 299860 310229 306245 294759 203703 224309 303377 115676 152843 264488 140918 139781 L-leucine Leucine 30355 25581 29184 25360 25964 30754 28013 18936 24391 30185 22576 25315 31465 23590 20924 L-lysine Lysine 15920 12888 19229 14692 18891 15216 9845 6054 7966 11522 14415 15891 18202 15717 13135 l-Norvaline 2S-Aminopentanoic acid 830600 801251 1065138 881171 816661 930729 752495 560470 687874 838603 641733 816203 952668 864564 685752 L-ornithine Ornithine 5085 5026 6859 6316 4861 5884 4756 3134 4867 6658 6774 6345 7574 6043 7077 L-proline Proline 159159 152178 187916 174706 169968 102451 103796 68716 69821 104899 148209 174582 212138 157688 139312 L-pyroglutamic acid Pyroglutamic acid 879976 870670 1003958 999483 942575 980090 823798 586293 661901 823650 659847 753931 1002759 871155 859433 L-serine Serine 302494 280480 351033 311078 307770 285163 263212 175525 201109 277335 284441 319561 376011 306642 280275 L- sorbose 2 Sorbose 14300 10797 16181 19010 15802 15269 12181 10015 11732 19597 22098 20333 19738 17877 18539 L-Threonic acid Threonic acid 7669 7829 10920 11070 7617 8196 6466 5248 7334 8387 9021 9216 13525 11720 9871 L-threonine Threonine 47428 49674 56570 46748 51705 43349 42301 27966 29770 41530 48796 52381 57772 49390 45876 L-tryptophan Tryptophan 6235 6031 7402 5479 5753 8924 7793 5613 6448 8587 6126 5960 7488 6299 5381 L-valine Valine 49534 48362 50421 50463 50143 49591 47230 32969 37124 51579 40408 48669 54976 42722 40126 malonic acid Malonic acid 17360 14262 15299 16730 15871 12967 14474 14133 6587 14298 13347 16891 19104 14254 13423 methyl oleate Methyl oleate 1737 801 1226 1005 1070 1660 1130 538 912 1577 1210 1672 1375 1128 413 Methyl Stearate (IS) Methyl stearate 107183 109424 112451 112668 112736 106508 109156 101952 109799 115912 110637 113513 113135 100690 103711 myo-inositol Myo-inositol 717135 728301 822391 686935 641841 785085 688760 492522 602842 756540 667291 727504 870789 680505 593405 Myo-Inositol_ 1_3_4_5_6-pentakis-O-(trimethylsilyl)-_ bis(trimethylsilyl) phosphate Myo-inositol 14657 11332 17616 13223 14366 17573 17484 12734 11202 17203 12699 11810 27689 15197 13552 myristic acid Myristic acid 4624 4030 3800 4371 4584 3937 2734 3374 3144 3238 3998 5199 5139 4565 3388 N-acetyl-L-aspartic acid N-Acetylaspartic acid 5902 18242 15889 31936 10026 28638 27199 25388 10059 26383 10194 11877 25696 9946 9708 nicotinamide Niacinamide 26111 23456 30780 28357 27703 39125 32448 25721 25228 40989 21394 24303 29201 22120 23187 oleic acid Oleic acid 208296 148442 250528 166535 155285 126831 115210 90706 135898 152940 190151 217516 239979 185798 142916 O-phosphocolamine Phosphoethanolamine 13244 13389 21992 18325 18588 16885 12059 9668 11069 13759 12750 15470 18950 21420 14246 O-phospho-L-serine Phosphoserine 3488 4122 2892 2654 2790 4386 4041 2936 4244 3206 3794 3066 4012 4708 5073 oxalic acid Oxalic acid 22249 26970 26124 28430 25720 25019 31042 26351 24678 26914 17806 27725 29952 22429 27313 palmitic acid Palmitic acid 292695 242437 360608 280940 242836 251963 215333 167555 222311 259109 253323 323178 383670 289568 219369 phenoxyethanol 1539 1415 1232 1015 1241 1118 1930 1324 1599 1253 1725 1230 1290 1521 1559 Phenylalanine Phenylalanine 23009 19806 20515 20808 21253 25816 27724 15841 22806 26739 18343 21081 24368 17079 15249 phosphoric acid Phosphoric acid 8101872 7508799 9396395 8111725 7511640 9442123 8050838 5518614 7442830 9123015 7428831 8755614 10148489 7817972 6579897 Phosphoric acid_ bis(trimethylsilyl)monomethyl ester Phosphoric acid 241563 255615 273998 291102 261841 291273 248403 205897 201679 262763 329142 367450 331418 244898 285893 putrescine Putrescine 1212 676 1655 1376 1093 1063 653 261 790 641 1297 1123 1840 1044 1580 pyrophosphate Pyrophosphate 37318 42041 37979 48516 40262 49940 49755 43635 42284 44885 40882 47616 39180 41979 38321 pyruvic acid Pyruvic acid 1620 2250 2132 2600 2253 1970 2642 1550 3177 2340 1822 1768 6853 2621 2107 ribonic acid-gamma-lactone 1 Ribonolactone 2707 3668 3213 2700 2481 2482 2305 1901 3907 2200 2255 3150 3503 2397 1887 ribulose-5-phosphate Ribulose 5-phosphate 3685 4452 5283 5822 3979 3662 4066 3521 3965 5119 6956 5566 5993 7997 5024 sarcosine Sarcosine 258329 339178 173206 284483 331435 178426 266170 275595 370282 274556 298712 197162 200384 208106 214556 Scyllo-Inositol Myo-inositol 19020 17331 19771 18241 19530 12918 11394 9285 12393 13547 13795 16615 22976 19950 15988 stearic acid Stearic acid 393507 325055 503587 389231 322209 382953 308242 252553 318467 406774 371290 467317 488074 378364 278756 succinic acid Succinic acid 5022 8517 6528 9618 7500 7464 8008 6550 6057 8361 8027 6606 10676 9221 9448 talose_R1 Talose 103707 87588 156881 143220 102154 60044 52929 44965 47502 80020 248357 213795 212812 247200 189252 talose_R2 Talose 12925 12334 20345 18545 13720 9078 8060 5482 5945 12335 34720 30794 27563 34712 26289 threose 2 Threose 1247 862 1424 1291 900 1317 1080 448 770 1469 1139 1754 985 1680 887 trans-4-hydroxy-L-proline 2 trans-4-Hydroxyproline 116783 113573 128774 131835 120020 130872 107397 78288 88391 108657 90581 102300 133715 115413 110924 tyrosine Tyrosine 30557 25736 35087 30190 30980 39876 36755 25105 28537 39339 28135 30814 36717 29678 22130 Uknown Monosaccharide 583873 554938 872656 805056 528965 386180 353605 278486 298191 518145 1323215 1180525 1145092 1351460 1046147 uracil Uracil 46856 44807 55983 50769 44225 52453 45893 35722 37691 53002 40822 49417 55203 47798 42899 urea Urea 61406 67469 75697 53197 58803 54943 55162 33866 36739 44749 45984 56882 63436 54703 54276 uric acid Uric acid 270935 273275 308953 257881 244742 298087 263040 186101 228717 290675 253580 276811 329465 257543 225445 xanthine Xanthine 68698 48858 86635 64080 64775 77727 51633 35530 47303 73602 61697 61623 57295 60318 46814