Metabolite_name RefMet_name 2 6 7 9 1 5 8 4 3 Ghost (blank) Factors - Condition:Healthy control Condition:Healthy control Condition:Healthy control Condition:Healthy control Condition:High-risk T1D Condition:High-risk T1D Condition:High-risk T1D Condition:New-onset (fasting) Condition:New-onset (post-prandial) Condition:Process blank 1_5-Anhydrosorbitol 1,5-Anhydrosorbitol 21.4600 22.4300 21.1300 21.4400 22.0100 22.5100 22.2200 22.3600 21.0900 1-Methyltryptophan 1-Methyltryptophan 14.4400 10.5500 11.8500 15.7700 12.5200 15.7200 14.2600 2-Hydroxybutyric acid 2-Hydroxybutyric acid 18.1700 19.0800 18.5700 19.3300 17.6000 19.3300 18.4900 18.3000 18.9200 2-Hydroxyisobutyric acid 2-Hydroxyisobutyric acid 13.5800 12.9100 13.2600 2-Hydroxyvaleric acid 2-Hydroxyvaleric acid 16.8700 15.2900 15.1300 15.1400 14.6600 16.3200 14.0800 16.5200 14.7200 2-Ketoleucine/ketoisoleucine 15.5500 16.7800 16.2200 16.9600 17.2200 16.9700 17.0200 17.0300 16.8700 2-Ketovaline 14.0500 14.2600 14.8400 14.7600 15.6000 15.4600 14.3300 15.6500 15.4800 3-Carboxy-4-methyl-5-propyl-2-furanpropanoic acid 3-Carboxy-4-methyl-5-propyl-2-furanpropanoic acid 12.9000 12.3700 12.5000 13.7300 13.2100 3-Hydroxybutyric acid 3-Hydroxybutyric acid 19.5500 21.9600 18.9200 17.7200 18.7400 20.3400 19.9400 18.9300 19.2500 3-Hydroxymethylglutaricacid 3-Hydroxymethylglutaric acid 19.6900 19.0400 3-Indolelactic acid 12.8400 14.0300 3-Indolepropionic acid 3-Indolepropionic acid 14.8000 13.6600 14.9700 11.1800 12.8800 13.7200 11.6700 14.9300 3-Methylhistidine 3-Methylhistidine 13.3200 11.8100 3-Methyloxyindole 3-Methyloxindole 15.8500 17.4000 3-Methyl pyruvic acid 3-Methyl pyruvic acid 11.2800 13 3-Phosphoglyceric acid 3-Phosphoglyceric acid 16.9900 14.7900 16.2300 5-Hydroxylysine 5-Hydroxylysine 12.3900 10.0800 12.8300 13.1400 12.1600 5-Methoxytryptamine/Serotonin 16.8900 16.6600 17.0700 6-Deoxyhexose 12.7800 12.7900 13.6900 13.7800 14.4400 14.0800 12.5400 13.1300 Alanine Alanine 21.1200 20.9000 21.0400 20.7300 20.2600 20.9000 20.4100 20.8500 20.1300 Aldopentoses 14.4600 14.6700 14.8900 13.8700 12.9200 12.1500 14.9600 12.7700 13.4100 alpha-Tocopherol alpha-Tocopherol 19.6000 19.6500 19.6200 19.3500 17.8500 18.8400 19.7600 19.6500 19.2400 Aminomalonic acid Aminomalonic acid 19.9000 20.5700 17.6400 20.1200 17.7300 20.6500 19.6800 AMP AMP 12.5800 10.3600 Arachidic acid/ 1-Heneicosanol 13.2400 13.6300 11.8700 12.4000 13.6500 13.7900 13.9700 13.9900 Arachidonic acid Arachidonic acid 17.5300 19.1400 18.2000 18.3400 16.2600 17.6100 18.2100 18.7800 17.9100 16.1800 Arginine/Citrulline 12.9300 12.1000 12.4000 Asparagine Asparagine 18.2100 18.5700 16.5300 17.5900 16.6500 18.8000 17.3300 17.6800 17.4500 Aspartic acid Aspartic acid 15.9600 15.3500 13.0100 14.4100 13.3000 16.1400 13.7800 15.2400 13.5600 beta-Alanine beta-Alanine 10.9900 12.5700 11.1700 11.9300 12.7400 Caffeine Caffeine 16.5100 14.8400 17.4800 13.5400 Campesterol Campesterol 13.0700 12.7400 13.1600 16.7000 11.6300 Capric acid Capric acid 11.4000 14.3200 15.6500 14.5900 13.3900 15.0500 12.9600 12.5200 Caprylic acid Caprylic acid 16.9700 15.1800 16.6300 14.4300 15.4200 15.4000 16.9000 15.7500 13 Cellobiose or similar disaccharide 18.8600 19.8000 19.1900 18.0500 16.2600 17.5700 16.9000 17.7500 14.9700 Cholesterol Cholesterol 25.8200 25.6700 25.7500 25.2200 24.0600 24.8600 25.6800 25.2500 25.3200 Citric acid/isocitric acid Citric acid/Isocitric acid 21.2600 22 19.6300 21.1500 19.5900 22.3800 20.9900 21.0500 20.5000 Cystine Cystine 16.7900 15.9500 16.3600 14.8400 17.4300 15.1300 14.1400 Dehydroascorbic acid L-Dehydroascorbic acid 19.9300 19.8800 17.0500 20.2400 19.7700 17.6900 18.8500 Docosahexaenoic acid Docosahexaenoic acid 15.7700 15.3100 14.2600 12.2700 14.2800 14.4800 14.3600 Erythronic acid Erythronic acid 16.0100 16.6800 15 16.2300 14.1100 16.5600 15.6600 16.3500 14.9500 Ethanolamine Ethanolamine 13.6700 15.5000 16.6300 14.8000 14.1700 15.0600 17.5900 15.0900 14.8000 Fructose or similar ketohexose Ketohexose 19.6800 17.3200 17.8200 17.8600 16.8500 18.9200 17.8200 19 16.2300 Fumaric acid Fumaric acid 11.7900 12.6200 13.2400 11.9300 gamma-Tocopherol gamma-Tocopherol 16.3500 16.0600 15.5100 16.7900 15.0300 15.4300 15.7400 15.3500 16.7700 Gentisic acid Gentisic acid 13.1700 12.0300 Gluconic acid Gluconic acid 19.8900 20.1400 19.3600 21.3400 18.7300 20.0500 19.2800 19.9000 19.0600 Glutamic acid Glutamic acid 18.5300 22.0200 17.9600 19.5200 19.3300 21.7200 18.4500 20.6300 17.5800 Glutamine Glutamine 21.5500 21.3900 19.5200 21.4900 19.7000 21.9400 20.4900 21.8800 20.5600 Glyceric acid Glyceric acid 17.1300 18.2800 17.0800 17.5700 15.7200 17.0900 17.3200 17.8900 16.3600 Glycerol Glycerol 20.9500 23.3600 24.2900 21.2500 21.3900 23.4000 23.9700 23.1200 18.2100 Glycine Glycine 18.6900 20.8500 19.8800 20.0600 18.9600 20.4400 20.8800 19.3400 19.6300 Glycolic acid Glycolic acid 16.6900 17.1600 15.4600 16.6500 17.5700 16.9500 15.3400 Heptadecanoic acid/Octadecanol 12.1500 14.3400 14.3400 13.9500 13.9400 15.8300 13.1800 14.8500 10.4500 Hexose Hexose 26.7600 26.6300 26.5600 26.9900 26.4500 26.7400 26.5700 26.7100 26.4900 10.4500 Hexose 6-phosphate Hexose 6-phosphate 10.8400 12.9700 10.7600 10.7000 Hippuric acid Hippuric acid 13.0100 14.4300 Histidine Histidine 18.2900 18.1400 15.1600 17.3100 15.8800 18.2200 16.1600 17.9400 16.1400 Hydroxyprolines 16.5700 16.2900 13.7700 16.8400 16.0400 19.5900 15.7400 16.4900 16.2800 Hypoxanthine Hypoxanthine 15.5000 14.3700 15.1100 15.3700 14.1400 10.4200 14.4800 13.4800 Indoleacetic acid Indoleacetic acid 14.2900 13.6000 12.3100 12.8200 12.6600 12.8200 13.2300 12.7800 Isoleucine/Leucine Leucine/Isoleucine 18.1100 18.2800 16.9100 16.4100 16.8300 19.4600 16.7500 17.8600 17.4500 Lactic acid Lactic acid 24.1300 24.2900 23.6000 24.8200 24.4000 25.3200 24.4900 24.1900 24.2500 12.8300 Lauric acid Lauric acid 13.9400 17.1400 16.2900 15.6500 16.1900 17.4500 14.7200 16.6000 Leucine Leucine 17.4900 17.5200 18.0700 16.8500 17.2900 17.9300 17.5300 17.6000 17.4900 Linoleic acid Linoleic acid 19.5300 22.5200 21.8000 20.4600 21.7900 21.5300 22.7800 21.1500 23.0500 17.0400 Lysine Lysine 20.6800 20.8000 19.7200 20.4700 18.5900 21.0300 20.0200 20.1600 19.8900 Maleic acid Maleic acid 15.7700 15.8000 13.3000 15.9700 15 16 Malic acid Malic acid 15.5400 17.7400 14.3000 15.5700 13.3600 16.8700 15.6600 16.5800 Maltose or similar disaccharide Maltose 16.6400 17.7900 17.0600 15.6000 12.4600 14.6700 13.6700 15.2200 11.9300 Methionine Methionine 17.4100 17.0500 13.6600 16.0400 15.8100 17.8500 15.8400 16.7300 15.4600 Methyl linoleate Methyl linoleate 18.7800 19.4100 19.5800 16.2700 15.4200 20.5900 17.5700 Methyl oleate Methyl oleate 18.2200 18.0200 18.3700 15.4700 14.2300 19.1400 16.5600 Methyl palmitate 21.5600 20.9900 21.2300 18.9200 16.7900 18.5700 21.5600 19.9500 16.6100 Methyl stearate Methyl stearate 21.5200 21.8400 22.0200 19.5300 16.5700 18.7200 22.5800 20.4600 17.9800 MG 0:0/16:0/0:0 MG 0:0/16:0/0:0 17.8000 17.9300 17.9300 18.0400 17.1400 18.0200 17.8000 18.0400 18.2600 15 MG 0:0/18:0/0:0 MG 0:0/18:0/0:0 21.0800 21.0800 21.1500 21.1700 20.5200 21.0400 20.9500 21.2200 21.5500 18.4400 MG 18:1(9Z)/0:0/0:0 MG 18:1(9Z)/0:0/0:0 13.0600 14.0700 13.6000 13.8700 12.2400 14.0700 15.3400 13.0200 13.5400 12.3800 Myo-inositol Myo-inositol 20.1700 20.0500 18.8800 19.8300 18.7500 19.8400 19.4900 20.1400 19.0800 Myristic acid Myristic acid 15.5100 16.9500 17.2000 14.4500 17.2900 16.7800 19.7200 15.8700 19.0200 12.1400 N-Methylalanine/2-Aminobutanoic acid 16.1000 16.0200 15.7600 15.2100 14.6200 16.4500 17.4800 15.3500 15.0900 Oleic acid Oleic acid 20.8700 23.1400 23.0300 20.6000 22.8900 22.7700 23.7400 21.5700 23.9700 14.8100 Ornithine Ornithine 18.8100 19.3000 19.6300 18.7700 18.4000 19.9000 19.1800 18.6200 18.4700 Oxoglutaric acid 2-Oxoglutaric acid 17 13.8800 15.7900 18.4300 17.6500 Palmitic acid Palmitic acid 22.4900 23.4000 23.0900 22.1500 23.1400 23.0600 23.6400 22.6800 23.8000 21.9000 Palmitoleic acid Palmitoleic acid 17.2700 19.2100 17.6100 16.6600 17.1100 19.1400 20.3700 17.5800 19.4900 P-Cresol P-Cresol 13.4600 12.1200 12.0700 11.8500 13.3600 13.5600 Pelargonic acid Pelargonic acid 13.0600 13.7700 12.2000 13.2200 11.2800 12.3200 Pentitols Arabitol 17.1100 15.6900 15.0600 15.4600 14.7400 16.3300 15.5800 16.1900 15.0100 Pentonic acids 13.1700 11.5900 13.7400 11.7000 14.0400 13.7500 Phenylalanine Phenylalanine 20.2800 20.2600 19.1200 19.2300 18.8300 20.8000 19.4600 20.1900 19.2800 Phosphoethanolamine Phosphoethanolamine 12.9000 15.1100 14.7700 Phosphoric acid Phosphoric acid 24.9200 25.2900 24.2900 25.0700 23.9300 25.4100 24.6500 25.0300 24.5900 20.0700 Proline Proline 19.9700 19.2400 17.6500 16.6200 18.5400 20.2000 17.1600 18.5500 17.4900 Pyrophosphate Pyrophosphate 16.0800 17.5800 16.8300 17.9200 14.7200 16.9300 16.8900 16.8100 16.7800 Pyruvic acid Pyruvic acid 19.1500 16.1200 17.7300 19.8400 19.2700 19.9000 19.6000 18.7600 19.5900 Quinic acid Quinic acid 13.1300 15.3600 15.5900 13.6700 14.1700 Serine Serine 19.9100 20.4800 15.9500 18.4300 17.6900 20.4400 17.4700 19.0200 18.1000 Shikimic acid Shikimic acid 16.2700 16.5700 14.3800 17.7600 15.7500 17.2100 15.4800 16.2300 Sitosterol Sitosterol 13.8800 12.8900 15.8100 sn-Glycero-3-phosphate sn-Glycero-3-phosphate 16.4700 17.7100 13.4100 15.3500 11.9400 16.5600 14.8400 16.8900 Succinic acid Succinic acid 19.0600 16.7800 16.4600 16.7900 Threitol/Erythritol 17.9200 16.8100 15.7100 16.6900 16.1100 17.3900 16.4900 16.9800 16.2400 Threonic acid Threonic acid 18.4300 19.0300 17.4800 18.4600 17.3600 17.7800 18.9800 17.8800 Threonine Threonine 21.5100 20.6900 17.3600 19.2600 18.9500 21.4400 18.0300 20.0600 18.8900 Tryptophan Tryptophan 17.9200 19.4700 18.9300 20.0300 18.8300 20.7900 19.2700 19.8000 18.7700 Tyrosine Tyrosine 20.3800 20.4600 19.9000 19.8200 19.2000 20.4000 20.1000 19.8200 19.7900 Uracil Uracil 12.9100 11.3200 Urea Urea 26.0300 25.5000 25.6000 25.4000 25.0500 26.2200 25.7300 26.2000 25.2500 Uric acid Uric acid 19.9700 21.8100 19.5200 21.1700 21.2000 21.4100 19.4200 21.2600 20.8100 Valine Valine 20.2800 19.4700 19.5900 18.9800 18.5300 20.3900 19.8300 20.1500 18.7800