Metabolite_name	RefMet_name	m02d	m06c	m18b	m07a-S5A	m11a-S5A	m13a-S5A	m15a-S5A	m11a	m14b	m17b	m05b	m13a	m14a	m01c	m03c	m07a	m01a	m02a	m08a	m01b-S5A	m07b-S5A	m08a-S5A	m09a-S5A	m01d	m07c	m11b	m01a-S5A	m06b-S5A	m10b-S5A	m18a-S5A	m03d	m15b	m16b	m04c	m12a	m15a	m04d	m05c	m08c	m03a	m04a	m05a	m11b-S5A	m13b-S5A	m14a-S5A	m17a-S5A	m04b-S5A	m06a-S5A	m10a-S5A	m12b-S5A	m02c	m03b	m10a	m09b	m10b	m13b	m02a-S5A	m05b-S5A	m14b-S5A	m16a-S5A	m04b	m06a	m09a	m03a-S5A	m04a-S5A	m09b-S5A	m12a-S5A	m16a	m17a	m18a	m06b	m07b	m12b	m02b-S5A	m03b-S5A	m05a-S5A	m08b-S5A	m01b	m02b	m08b	PS.079	PS.057-10.4	PS.057-10.6	BG1C0473-11	PS.158	BG1C0466-12	PS.120-13.3	PS.120-13.9	BG1C0466-13	BG1C0473-13	PS.132	Bgsng8064	PS.170	PS.004	Bgsng8119	Bgsng8169-28	Bgsng8169-30	Bgsng8153	BG1C0462	PS.011
Factors	-	Cage:1 | Microbiota:26-member | Diet:NAD-precursor deficient | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:1 | Microbiota:26-member | Diet:NAD-precursor deficient | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:1 | Microbiota:26-member | Diet:NAD-precursor deficient | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:1 | Microbiota:26-member | Diet:NAD-precursor sufficient | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:1 | Microbiota:26-member | Diet:NAD-precursor sufficient | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:1 | Microbiota:26-member | Diet:NAD-precursor sufficient | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:1 | Microbiota:26-member | Diet:NAD-precursor sufficient | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:1 | Microbiota:BthetaBxylan | Diet:NAD-precursor deficient | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:1 | Microbiota:BthetaBxylan | Diet:NAD-precursor deficient | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:1 | Microbiota:BthetaBxylan | Diet:NAD-precursor deficient | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:1 | Microbiota:Btheta | Diet:NAD-precursor deficient | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:1 | Microbiota:Btheta | Diet:NAD-precursor deficient | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:1 | Microbiota:Btheta | Diet:NAD-precursor deficient | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:1 | Microbiota:Bxylan | Diet:NAD-precursor deficient | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:1 | Microbiota:Bxylan | Diet:NAD-precursor deficient | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:1 | Microbiota:Bxylan | Diet:NAD-precursor deficient | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:1 | Microbiota:Germfree | Diet:NAD-precursor deficient | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:1 | Microbiota:Germfree | Diet:NAD-precursor deficient | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:1 | Microbiota:Germfree | Diet:NAD-precursor deficient | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:1 | Microbiota:Germfree | Diet:NAD-precursor sufficient | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:1 | Microbiota:Germfree | Diet:NAD-precursor sufficient | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:1 | Microbiota:Germfree | Diet:NAD-precursor sufficient | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:1 | Microbiota:Germfree | Diet:NAD-precursor sufficient | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:2 | Microbiota:26-member | Diet:NAD-precursor deficient | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:2 | Microbiota:26-member | Diet:NAD-precursor deficient | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:2 | Microbiota:26-member | Diet:NAD-precursor deficient | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:2 | Microbiota:26-member | Diet:NAD-precursor sufficient | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:2 | Microbiota:26-member | Diet:NAD-precursor sufficient | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:2 | Microbiota:26-member | Diet:NAD-precursor sufficient | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:2 | Microbiota:26-member | Diet:NAD-precursor sufficient | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:2 | Microbiota:BthetaBxylan | Diet:NAD-precursor deficient | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:2 | Microbiota:BthetaBxylan | Diet:NAD-precursor deficient | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:2 | Microbiota:BthetaBxylan | Diet:NAD-precursor deficient | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:2 | Microbiota:Btheta | Diet:NAD-precursor deficient | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:2 | Microbiota:Btheta | Diet:NAD-precursor deficient | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:2 | Microbiota:Btheta | Diet:NAD-precursor deficient | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:2 | Microbiota:Bxylan | Diet:NAD-precursor deficient | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:2 | Microbiota:Bxylan | Diet:NAD-precursor deficient | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:2 | Microbiota:Bxylan | Diet:NAD-precursor deficient | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:2 | Microbiota:Germfree | Diet:NAD-precursor deficient | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:2 | Microbiota:Germfree | Diet:NAD-precursor deficient | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:2 | Microbiota:Germfree | Diet:NAD-precursor deficient | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:2 | Microbiota:Germfree | Diet:NAD-precursor sufficient | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:2 | Microbiota:Germfree | Diet:NAD-precursor sufficient | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:2 | Microbiota:Germfree | Diet:NAD-precursor sufficient | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:2 | Microbiota:Germfree | Diet:NAD-precursor sufficient | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:3 | Microbiota:26-member | Diet:NAD-precursor deficient | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:3 | Microbiota:26-member | Diet:NAD-precursor deficient | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:3 | Microbiota:26-member | Diet:NAD-precursor deficient | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:3 | Microbiota:26-member | Diet:NAD-precursor deficient | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:3 | Microbiota:Btheta | Diet:NA-supplementeded | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:3 | Microbiota:Btheta | Diet:NA-supplementeded | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:3 | Microbiota:Btheta | Diet:NA-supplementeded | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:3 | Microbiota:Bxylan | Diet:NA-supplementeded | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:3 | Microbiota:Bxylan | Diet:NA-supplementeded | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:3 | Microbiota:Bxylan | Diet:NA-supplementeded | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:3 | Microbiota:Germfree | Diet:NAD-precursor deficient | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:3 | Microbiota:Germfree | Diet:NAD-precursor deficient | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:3 | Microbiota:Germfree | Diet:NAD-precursor deficient | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:3 | Microbiota:Germfree | Diet:NAD-precursor deficient | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:3 | Microbiota:Germfree | Diet:NA-supplementeded | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:3 | Microbiota:Germfree | Diet:NA-supplementeded | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:3 | Microbiota:Germfree | Diet:NA-supplementeded | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:4 | Microbiota:26-member | Diet:NAD-precursor deficient | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:4 | Microbiota:26-member | Diet:NAD-precursor deficient | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:4 | Microbiota:26-member | Diet:NAD-precursor deficient | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:4 | Microbiota:26-member | Diet:NAD-precursor deficient | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:4 | Microbiota:Btheta | Diet:NA-supplementeded | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:4 | Microbiota:Btheta | Diet:NA-supplementeded | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:4 | Microbiota:Btheta | Diet:NA-supplementeded | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:4 | Microbiota:Bxylan | Diet:NA-supplementeded | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:4 | Microbiota:Bxylan | Diet:NA-supplementeded | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:4 | Microbiota:Bxylan | Diet:NA-supplementeded | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:4 | Microbiota:Germfree | Diet:NAD-precursor deficient | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:4 | Microbiota:Germfree | Diet:NAD-precursor deficient | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:4 | Microbiota:Germfree | Diet:NAD-precursor deficient | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:4 | Microbiota:Germfree | Diet:NAD-precursor deficient | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:4 | Microbiota:Germfree | Diet:NA-supplementeded | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:4 | Microbiota:Germfree | Diet:NA-supplementeded | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:4 | Microbiota:Germfree | Diet:NA-supplementeded | Age (months):NA | WLZ:NA | Health phenotype:NA	Cage:NA | Microbiota:NA | Diet:NA | Age (months):10.3 | WLZ:-2.7 | Health phenotype:Malnourished	Cage:NA | Microbiota:NA | Diet:NA | Age (months):10.4 | WLZ:-3.8 | Health phenotype:Malnourished	Cage:NA | Microbiota:NA | Diet:NA | Age (months):10.6 | WLZ:-2.81 | Health phenotype:Malnourished	Cage:NA | Microbiota:NA | Diet:NA | Age (months):11 | WLZ:-0.82 | Health phenotype:Healthy	Cage:NA | Microbiota:NA | Diet:NA | Age (months):12.5 | WLZ:-3.48 | Health phenotype:Malnourished	Cage:NA | Microbiota:NA | Diet:NA | Age (months):12 | WLZ:0.2 | Health phenotype:Healthy	Cage:NA | Microbiota:NA | Diet:NA | Age (months):13.3 | WLZ:-3.16 | Health phenotype:Malnourished	Cage:NA | Microbiota:NA | Diet:NA | Age (months):13.9 | WLZ:-2.17 | Health phenotype:Malnourished	Cage:NA | Microbiota:NA | Diet:NA | Age (months):13 | WLZ:-0.3 | Health phenotype:Healthy	Cage:NA | Microbiota:NA | Diet:NA | Age (months):13 | WLZ:-0.93 | Health phenotype:Healthy	Cage:NA | Microbiota:NA | Diet:NA | Age (months):14.1 | WLZ:-3.01 | Health phenotype:Malnourished	Cage:NA | Microbiota:NA | Diet:NA | Age (months):15 | WLZ:0.6 | Health phenotype:Healthy	Cage:NA | Microbiota:NA | Diet:NA | Age (months):16.2 | WLZ:-3.5 | Health phenotype:Malnourished	Cage:NA | Microbiota:NA | Diet:NA | Age (months):21.9 | WLZ:-2.03 | Health phenotype:Malnourished	Cage:NA | Microbiota:NA | Diet:NA | Age (months):25 | WLZ:1.7 | Health phenotype:Healthy	Cage:NA | Microbiota:NA | Diet:NA | Age (months):28 | WLZ:- | Health phenotype:Healthy	Cage:NA | Microbiota:NA | Diet:NA | Age (months):30 | WLZ:1.77 | Health phenotype:Healthy	Cage:NA | Microbiota:NA | Diet:NA | Age (months):6 | WLZ:1.58 | Health phenotype:Healthy	Cage:NA | Microbiota:NA | Diet:NA | Age (months):8 | WLZ:-0.43 | Health phenotype:Healthy	Cage:NA | Microbiota:NA | Diet:NA | Age (months):9.9 | WLZ:-5.54 | Health phenotype:Malnourished
Aspartate	Aspartic acid	143.1900	138.3400	164.2000	84.7400	65.3600	187.8900	52.5600	3.8300	10.6500	5.2300	3.7700	8.5400	10.3900	8.2500	6.6500	8.7400	301.6700	213.5800	171.6900	10.5700	9.8100	16.8600	6.6000	148.1400	141.3500	121.1900	71.2900	56.8400	56.5000	77.6700	14.4900	8.1300	6.4300	5.9400	6.0700	7.4900	35.3300	11.2000	10.1200	215.2000	122.8700	204.8400	14.2600	57.8300	20.8700	31.8800	113.7500	101.7400	94.8900	204.5500	18.0700	11.3000	11	6.1900	6.1100	20.0700	90.0900	79.0900	109.5600	86.6100	250.6500	224.2900	162.7700	119.9300	117.9300	131.8200	94.3200	9.8100	14.6400	10.1500	5.6800	6.2500	11.5700	109.2400	115.0300	111.7000	79.3200	173.3700	229.2100	256.1900	6.2900	181	192.5200	204.4200	92.8800	568.1500	15.1400	70.1700	206.8700	629.3700	439.4800	1879.0900	111.6400	59.1500	79.0500	138.8900	346.1300	134.2200	683.4500	23.8700
NAD	NAD	0.7490	1.1820	0.9700	0.0980	0.0150	0.0670	0.0370	0.6120	0.5350	1.4960	2.9270	1.5070	0.5250	0.1990	0.7510	0.1100	0.4160	0.2280	0.2500	0.0120	0.0220	0.0230	0.0270	0.6310	0.5130	0.6740	0.0210	0.0230	0.0300	0.0410	0.4990	0.7830	0.5390	0.9830	0.3150	0.3200	0.5460	0.4160	0.2390	0.1970	0.1610	0.2160	0.0090	0.0080	0.0270	0.0210	0.0150	0.0200	0.0170	0.0180	1.3650	2.4510	1.0490	0.5800	1.3410	1.2640	0.0150	0.0180	0.0280	0.0190	0.1730	0.3730	0.2000	0.0170	0.0240	0.0200	0.0270	1.6300	1.0820	2.1090	1.0490	0.4570	1.3060	0.0150	0.0420	0.0240	0.0110	0.2230	0.2650	0.3110	0.3900	0.5130	1.0750	0.0620	0.5820	0.0390	0.2500	0.3290	0.1380	0.8550	0.4590	0.0780	0.7120	0.1540	0.0850	0.0890	0.0360	0.0500	0.0110	0.2300
Nam	Niacinamide	0.1410	0.1950	0.1440					0.1030	0.0730	0.0900	0.0670	0.1870	0.1030	0.0770	0.0750	0.0780	0.0190	0.0050	0.0660					0.1820	0.1110	0.0730					0.1090	0.1590	0.0650	0.0670	0.1160	0.1110	0.5820	0.1810	0.0960	0.0130	0.0110	0.0090									4.2340	5.3670	4.9860	2.2160	1.6570	2.7010					1.1060	1.2540	1.1370					2.7860	3.0430	3.6020	2.2110	1.5520	1.4860					1.6380	1.4570	2.6390				0.0020					0.0020		0.0080				0.0110			0.1500		
Nicotinic acid	Nicotinic acid	0.3190	0.2320	0.2330	5.1300	9.7300	7.3000	6.7900	0.0010	0.0030	0.0010	0.0010	0.0010	0.0010	0.0010	0.0010	0.0010	0.0010	0.0010	0.0010					0.2650	0.1470	0.1050	4.3200	3.5600	4.0800	3.6300	0.0010	0.0010	0.0010	0.0010	0.0010		0.0010	0.0010	0.0010	0.0010	0.0010	0.0010					2.3700	1.7200	2.3300	2.5800	0.0030	0.0050	0.0050	0.0050	0.0030	0.0080					0.0030	0.0070	0.0070	2.2000	1.8800	3.8400	1.1700	0.0030	0.0030	0.0040	0.0060	0.0050	0.0040					0.0040	0.0040	0.0100	0.0600	0.1700	0.2100	1.3900	0.0100	2.6800	0.1000	0.2600	6.0200	0.9000	0.0200	2.1600	0.0100	0.1700	3.1800	4.0100	6.3000	0.1100	0.3700	0.1800
v-cADPR-x		0.4310	0.3380	0.2780	0.0100	0.0070	0.0160	0.0100	0.2000	0.3040	0.3470	0.1800	0.1600	0.1500	0.7670	0.8380	0.6190	0.1810	0.1900	0.1770	0.0050	0.0050	0.0040	0.0050	0.2840	0.2610	0.2610	0.0100	0.0110	0.0100	0.0100	0.1940	0.2770	0.3560	0.1470	0.1740	0.1570	0.8670	0.9350	0.8790	0.2200	0.1320	0.2090	0.0060	0.0060	0.0030	0.0020	0.0100	0.0100	0.0070	0.0150	0.1490	0.1560	0.1340	0.6720	1.2130	0.4790	0.0030	0.0050	0.0070	0.0050	0.1570	0.1530	0.1530	0.0070	0.0110	0.0080	0.0100	0.2090	0.1690	0.1700	1.1480	0.7570	0.8150	0.0030	0.0050	0.0030	0.0030	0.1150	0.2050	0.2060	0.0020	0.0020	0.0050	0.0100	0.0050	0.0050	0.0020	0.0060	0.0110	0.0090	0.0050	0.0610	0.0020	0.0030	0.0070	0.0020	0.0030	0.0030	0.0030	0.0030