Metabolite_name RefMet_name C1 C2 C3 C4 C5 C6 QC-1 QC-2 QC-3 C13 C14 C15 C16 C17 C18 C7 C8 C9 C10 C11 C12 Factors - Factor:noStressHeLa Factor:noStressHeLa Factor:noStressHeLa Factor:noStressKDOGA Factor:noStressKDOGA Factor:noStressKDOGA Factor:QC Factor:QC Factor:QC Factor:RecoveryHeLa Factor:RecoveryHeLa Factor:RecoveryHeLa Factor:RecoveryKDOGA Factor:RecoveryKDOGA Factor:RecoveryKDOGA Factor:StressHeLa Factor:StressHeLa Factor:StressHeLa Factor:StressKDOGA Factor:StressKDOGA Factor:StressKDOGA 1_3-diphopshateglycerate 33046.5611 23228.0654 19104.0562 37719.0080 29898.0622 35568.2379 39281.8991 27186.7563 31597.8858 26002.8412 29679.1697 45393.4952 24212.6805 38468.5525 25645.0923 20928.3300 21472.2117 47587.3538 20711.5535 27594.7827 22123.4818 acetyl-CoA_pos Acetyl-CoA 4216.5367 3444.6940 3222.5160 2111.3180 1222.3660 5547.5692 5842.8945 4734.5607 10112.5340 3389.1299 2228.2514 6278.9303 3795.7881 1914.0093 6226.2260 8167.6572 7896.1391 8482.2659 9692.8452 2858.5059 aconitate trans-Aconitic acid 1028253.4030 600000.9283 1039753.9090 579803.9136 851461.0121 966481.4801 563377.7200 725256.0002 827170.2885 1072694.5670 525110.4265 943045.8058 394544.0557 513337.5833 216992.4391 464193.0778 532030.2559 577813.9272 287560.4549 280381.4505 161722.7819 ADP_neg ADP 94010.2671 109425.9428 160825.7256 227313.0723 164439.9251 287447.9468 105651.6534 181591.6507 146712.7704 27830.2400 56047.0962 177465.8719 165627.1737 67372.9724 43231.8960 112204.5193 369017.4532 448791.0503 122494.9597 171238.9014 110137.4096 a-ketoglutarate 2-Oxoglutaric acid 2772315.5210 3230655.1750 3474859.4400 2411937.9730 2389674.5400 1988040.2370 2499614.0520 2745626.3230 2935306.7160 2441496.4940 2156642.2500 3048366.6670 1311045.6460 1362834.2590 753757.3492 5787684.3040 5346278.9620 5973980.5340 2638659.4870 1773551.4220 3028993.9410 ATP_neg ATP 94104.3631 54782.3436 156126.3667 1225223.6600 354875.7240 427131.8226 67498.4104 297967.2014 236555.3403 315936.9912 207889.5444 208319.1740 213500.5610 110918.4619 216934.7543 852676.9519 462806.9307 741115.6102 262592.5929 381547.3611 226763.1141 CDP-choline CDP-choline 34615.0112 35227.3268 38426.3363 48672.7713 43491.8905 29621.0232 296475.6542 315660.0231 325389.5854 797528.5309 791198.3480 1033070.5350 417055.8873 488517.8722 438730.5856 230752.6354 242394.3823 282453.8359 406265.2556 386345.0622 447576.3580 CDP_neg CDP 22443.8819 14608.9255 9674.6187 12483.0184 2984.3980 19383.4305 5582.7288 31125.2072 22133.6512 87802.9114 35978.7660 58404.1173 33409.3727 16846.5600 51843.4474 12926.4677 14279.8583 22012.7518 13561.0698 27736.4105 10242.5498 citrate Citric acid 55598.0832 28496.6971 57952.4462 40647.4744 110326.8270 29308.5865 85685.3647 57772.3476 73919.9355 69449.4931 57193.6872 23114.6243 32500.2202 88993.3938 46003.2493 10009.8032 38699.6734 80524.1491 19894.9035 21397.4726 10221.0321 citrate-isocitrate Citric acid/Isocitric acid 724801.4908 272096.8502 218915.8260 260404.9083 462203.3343 137388.0686 68262.8424 207634.6567 148427.4706 373570.1800 141865.6033 62244.6270 120209.8042 85751.2330 57175.3481 211957.9027 160472.0329 227918.5040 61553.0883 45360.6487 84922.9890 coenzyme A_neg Coenzyme A 666.8233 499.9554 277.8447 833.4327 1055.7106 333.4680 388.9394 222.3307 889.0426 608.1420 777.8107 CTP_neg CTP 11043.9504 35582.9166 8021.5912 31620.1843 16474.9855 12295.9308 21984.6460 28027.1209 22177.1675 6267.6432 42857.1996 958.3947 10301.8434 30480.9656 21745.9607 6693.0617 5618.0350 5880.0121 3047.0686 7543.3589 20471.8459 D-glyceraldehdye-3-phosphate Glyceraldehyde 3-phosphate 1611620.4090 1442289.2990 1748049.2810 1304070.3620 1303022.8450 1135063.6580 1303557.2690 1498778.5720 1540063.7940 2075404.2380 1936156.1690 2814841.3020 1538862.6460 1467522.9930 1391708.1290 1450067.1280 1284833.9350 1407053.9480 1529179.7900 1360650.2870 1216393.2060 FMN FMN 2444.6108 1191.8180 1669.7274 500.0274 503.0773 1055.7053 3611.6127 1163.8174 1268.9120 777.8553 1000.2127 1832.9862 1058.2478 1108.2365 1333.3767 2278.0319 1722.3320 1830.6226 fructose-1_6-bisphosphate Fructose 1,6-bisphosphate 985.5093 22837.5561 57422.3596 207171.7253 48068.2447 310.8919 790.9549 2882.3305 1984.1841 357.7074 3432.6232 553.2612 1909.6438 61438.7041 2430.3432 fructose-6-phosphate Fructose 6-phosphate 349917.5690 270302.2488 375030.6147 317263.9949 368821.1438 368182.5354 144400.2669 183104.8004 174611.0121 207117.9611 136283.4800 285395.0518 32163.9406 61076.2620 70862.4075 100754.5690 95501.2823 61294.1119 63220.9143 69884.5452 76680.5116 fumarate Fumaric acid 983477.2662 848643.9611 1076461.6120 544149.0571 585273.3974 534696.8648 622914.0293 897298.6989 755757.4333 459383.1539 392290.0190 565047.0991 369931.0774 156694.3533 147158.7443 1057240.5920 1032799.4820 1445980.4890 633156.0234 663134.8472 554336.5136 GDP_neg GDP 17882.4569 8388.2845 7114.3069 7635.5288 5875.4471 13336.8844 12745.8210 16530.3550 11615.3838 12522.8629 2731.5632 9949.1750 14139.3352 7024.0006 4745.4503 1832.3147 11604.1146 8408.1169 9497.7623 3005.6968 5472.6099 glucose-6-phosphate Glucose 6-phosphate 416747.0147 339895.6007 427366.6647 255406.2112 389959.8145 378964.3708 206404.4730 225558.1808 263643.1781 245619.7551 239830.5140 357836.4437 65810.8028 61877.3217 49968.1740 112732.4234 91193.5638 138404.9646 84375.7670 87660.1080 46021.3331 glyoxylate Glyoxylic acid 32288.0582 12792.6979 11529.8408 20098.5058 6675.9194 2753.8931 14892.8910 1128.0520 262.3977 10169.1793 777.7501 8233.8343 1887.4955 166.6500 3662.2068 GTP_neg GTP 45059.7059 38490.6082 91748.1973 34574.2054 13718.6185 91979.0055 2408.6172 33825.2955 37162.0859 69818.2746 49804.3812 13523.7458 48210.3507 15863.5193 11481.8020 81022.7195 69620.9740 99260.3023 44338.8053 11852.1259 13881.8756 isocitrate Isocitric acid 305558.9162 50802.9804 89694.8811 168416.2034 9843.8161 310270.8063 12278.0812 1554.1219 472.3827 2872.0135 222.2213 666.6726 4369.0432 5775.3231 13231.9749 719.1760 469.6710 8174.6854 lactate Lactic acid 35320683.2000 30084292.3500 28977465.6500 19440637.6300 15551930.9800 11163731.8800 16617080.2900 16144649.8900 16571702.4700 23934312.9500 11830689.8700 13662355.3800 14104004.2400 19433677.2700 10424782.5500 7933898.6370 8729060.8350 7999760.9580 11253795.2100 8941972.2950 6781493.8790 malate Malic acid 39704389.4500 34736253.5900 44405577.1000 20519306.4100 24324024.1800 20938954.7800 22654785.9900 29346925.0200 29682833.2800 18020143.4200 14392363.2900 20935722.5200 5182921.0990 5257567.3000 5017525.7570 45518155.6200 43085177.1000 55334878.3600 26438572.8100 24712985.5200 22069534.4200 N-acetyl-glucosamine-1-phosphate N-Acetylglucosamine 1-phosphate 50288.3967 51006.8893 16801.3586 223626.0271 193350.3526 202274.9449 117012.1743 123266.0288 122755.2385 43813.9344 33553.2905 59913.9431 89599.8705 96663.3020 70593.0819 31720.3571 48724.3203 38314.6395 379393.9578 293539.2486 241988.5903 NADH_neg NADH 48459.9948 57862.0458 52213.5604 40589.9526 39283.0571 47883.5207 25505.7926 18785.0953 28781.7188 27558.2221 23669.8114 13375.7975 8890.5132 4497.6760 9667.6407 23058.4066 22780.6649 23724.4771 17779.8331 19057.8341 15223.8557 NAD+_neg NAD 10903558 11395295.0700 12039532.6700 9616295.6770 8110462.0920 9272908.2430 4639777.5840 5010336.4220 5284903.8810 2669562.0690 2578212.2990 3455462.8780 728930.7295 705386.9497 826830.0363 4519403.6230 4211134.2490 4416688.3480 2727026.4120 2737738.1960 2150831.0390 NADPH_neg NADPH 29534.4999 6589.9814 29164.3512 12488.5857 24791.8132 19004.4652 22638.9736 25125.6198 29724.9238 36488.8757 30726.1117 30362.6531 15281.3471 16890.7427 6972.9754 36660.7616 26099.5018 29953.7715 15986.0671 26904.7253 25436.4956 NADP+_neg NADP 111666.3937 74398.8536 192315.2157 87010.5263 55363.3020 91898.1679 157596.8874 59452.8649 174793.7046 150024.8459 92424.8839 143959.6233 12773.5196 65014.1055 41186.6066 209918.8285 64125.2408 50741.6399 239187.5862 204924.4833 77898.1881 oxaloacetate Oxaloacetic acid 550277.6444 26982.4216 359365.2442 105390.0847 232622.9566 68382.7000 202740.6685 169188.3982 22338.5237 8631.1876 2659.0887 8708.1087 3054.1170 444.4426 9982.3952 14385.5340 phosphoenolpyruvate Phosphoenolpyruvic acid 19972.6860 15624.2388 9165.1959 20495.7912 24308.0122 20660.4450 8521.4628 9531.6701 26015.9954 25043.3320 18477.9438 23829.2386 17114.3719 14215.9887 16781.3969 22463.4190 8389.7022 14269.7756 9722.0349 10068.2651 16280.5445 pyruvate Pyruvic acid 478013.0876 383633.1115 347872.2493 284065.6829 256709.1361 192468.2997 859656.1384 1008802.5040 986468.7311 2472415.5170 946915.3947 576136.8157 1945109.4450 2432779.4250 837842.2024 499936.4151 516766.3693 533755.7418 430731.4167 527085.5792 608688.2267 succinate Succinic acid 566386.5132 487514.0043 505512.6993 482190.3400 397916.6488 302217.2770 737807.3162 835026.2179 765887.2740 973199.1856 512468.7245 639880.1519 793960.3098 1047852.7400 440535.9780 1858787.3730 1706622.7040 1663319.3120 1041787.9730 1087686.3990 909510.5129 succinyl-CoA-methylmalonyl-CoA_neg 277.8287 277.9073 388.8713 611.1607 222.2160 499.9820 222.2213 222.3573 UDP-N-acetyl-glucosamine UDP-N-acetylglucosamine 1242851.1120 1255651.2580 1452987.6310 5616991.3520 5815845.2620 5142335.8640 2482319.2860 3113221.8960 3017737.5140 1756252.5770 1555367.1970 2183496.4160 2039523.9540 2501221.1620 1905489.7140 1335113.5020 1194855.3640 1266787.6910 6350817.7260 6499511.9800 6182165.7880 UDP_neg UDP 20306.2997 21864.1382 24804.1852 76290.8433 101401.9249 44188.7667 38724.2462 48502.8214 48619.4146 22946.1063 28630.7855 31144.3238 26569.3906 40336.6437 30342.3401 20264.2607 15895.2540 18115.1047 97076.2187 98215.5003 90158.6737 UTP_neg UTP 205648.4890 160093.3591 184298.9388 91000.1102 74433.6119 188225.2545 176640.8180 238570.2653 61597.2619 93071.1076 603069.3403 84739.2537 184328.0227 86859.6081 132492.2087 126979.1628 349271.5545 120777.7902 113735.9470 144083.6223 92824.9291