Metabolite_name RefMet_name FAR_T90_min-1 FAR_T90_min-2 FAR_T90_min-3 FAR_T90_min-4 XR_T90_min-1 XR_T90_min-2 XR_T90_min-3 XR_T90_min-4 Factors - Strain:FAR Strain:FAR Strain:FAR Strain:FAR Strain:XR Strain:XR Strain:XR Strain:XR 10-formyldihydrofolate 1186779 1215621 1240861 1189742 1 1 1 1 1_4-beta-D-Glucan 1,4-beta-D-Glucan 92968 100402 90373 71069 200223 174029 154454 144946 2-Dehydro-3-deoxy-6-phospho-D-gluconate 2249726 1961212 1803977 1599133 1529548 1 1 1096723 2-Deoxy-2_3-dehydro-N-acetylneuraminic acid 2-Deoxy-2,3-dehydro-N-acetylneuraminic acid 93972 73658 68139 1 1 1 1 1 2-Isopropylmalic acid 2-Isopropylmalic acid 87338 85478 87128 94027 177022 146575 136477 1 2-Keto-3-deoxy-D-gluconic acid 2-Dehydro-3-deoxy-D-gluconic acid 3157896 2937049 2170335 1993815 4436841 4681198 4485047 2912518 2-Octaprenylphenol 2-Octaprenylphenol 23015 26398 34122 7261 15111 1 1 1 2-oxo-octadecanoic acid 2-Oxo-octadecanoic acid 1 1 1 1 147429 1 18583 18405 3-hydroxy-hexadecanoic acid 3-Hydroxyhexadecanoic acid 156685 1 152322 175131 36521 16688 1 1 3-Methylcrotonyl-CoA 3-Methylbut-2-enoyl-CoA 170078 148592 139362 129889 92119 67337 1 1 3-oxo-hexanoyl-CoA 3-Oxohexanoyl-CoA 58485512 51493848 45640508 42374400 31996658 25567920 22671876 20896008 3-Oxohexanoyl-coenzyme A 3-Oxohexanoyl-CoA 20894 9988 1 14628 1 1 1 1 4-Hydroxyphenylacetyl-CoA 108680 92077 78911 61703 21701 1 12775 1 4-Phospho-D-erythronate 1 245103 398437 691419 2853980 2337664 2469629 2824609 4-Phosphopantothenoylcysteine 251446 225497 250541 230985 80167 1 80358 71429 5^-Adenylyl sulfate (APS) 204479 229591 268391 314395 45959 51490 1 70894 5^-Methylthioadenosine 5'-Methylthioadenosine 125428 121686 1 103801 1 1 1 1 6-Phosphogluconic acid 6-Phosphogluconic acid 1 1 77946 1 233520 149111 231345 1 Acetyl adenylate Acetyl adenylate 1 3034 1 1 40133 31449 32744 20162 Acetyl-CoA Acetyl-CoA 1 230969 222460 1 500174 414565 383668 377916 Adenosine 5^-triphosphate (ATP) ATP 258169 217494 231303 281535 788840 593837 563846 597187 Adenylosuccinic acid Adenylsuccinic acid 6074259 4530166 4005703 2799391 8457253 6405143 5540189 4852531 ADP / Adenosine 5^-diphosphate ADP 6848601 6325008 6079824 6277373 10879929 9074512 8485527 7755792 ADP-glucose ADP-glucose 5147 12881 1 16393 1 1 1 1 ADP-ribose 1″-2″ cyclic phosphate 1 1 1 1 447675 165988 46512 137442 beta-Lactose Lactose 156866 156290 164858 129909 104608 93767 94878 97602 Citric acid Citric acid 1 78333 34073 113267 1 1 1 1 Coenzyme A (CoA) Coenzyme A 28082 25656 22613 1 51011 55358 1 1 dCMP / 2^-Deoxycytidine 5^-monophosphate 483602 476804 456225 395757 368118 1 392330 1 D-Fructose 6-phosphate Fructose 6-phosphate 290758 1 219137 225601 411175 411856 1 361486 D-Gluconic acid Gluconic acid 50753408 49065720 48756120 49851332 73515384 69048048 67610552 67505840 D-Glucose 6-phosphate Glucose 6-phosphate 9316200 8065931 7684630 7530315 5361903 4762682 4371415 4326650 D-Glycerate 3-phosphate 3-Phosphoglyceric acid 1 1 1 1 410003 332025 342679 1 DHAP(18:0e) 400601 424484 421555 419936 1294799 1189597 1017330 1150656 Dihydroxyacetone (glycerone) Dihydroxyacetone 628291 595633 619738 569728 1 1 276923 1 DL-3-amino-isobutanoic acid 3-Aminoisobutanoic acid 1 1 1 1 1 244983 262264 257517 D-myo-Inositol-1_3_4-triphosphate 233533 176711 130427 480627 1 83541 1 1 D-Pantetheine 4^-phosphate Pantetheine 4'-phosphate 51244 1 1 1 92126 92764 1 79622 D-Pantothenic acid Pantothenic acid 1 1 710448 1 1684375 1 1102384 913820 D-Ribulose 5-phosphate Ribulose 5-phosphate 698966 661889 1 606435 1 360769 325350 1 D-Sedoheptulose-7-phosphate D-Sedoheptulose 7-phosphate 1215197 1 1088493 1171589 355572 322852 1 1 D-Sorbitol Sorbitol 1 1 1 1 1634316 1675453 1674035 1659553 D-Tagatose 1_6-bisphosphate 1 1 1 1 2818617 1 2162629 1991458 dTDP-L-rhamnose 1 1 1 1 89989 76962 72440 1 dTTP / 2^-Deoxythymidine 5^-triphosphate 638671 588874 519462 601146 1475830 1107446 1 949729 GDP-L-fucose GDP-L-fucose 47687 1 1 1 76072 116244 1 129854 Glutamyl-gamma-glutamate 1 1 30838 1 166862 77034 46020 23287 Glutathionylspermine 262189 177602 182552 382845 755341 805100 936858 1008452 GSH / Glutathione 15465056 13133888 11507527 9207109 23967672 19013876 15463257 13002889 GSSG / L-Gluthathione (oxidized) 7478 1 1 1 1 12125 6119 34509 Guanosine 3^_5^-bis(diphosphate) 1 1 1 163467 311855 256260 255555 150007 Gulonic acid Gulonic acid 1 1 1 1 238517 154787 183553 32156 Hexanoyl-CoA Hexanoyl-CoA 49925 33703 20048 14972 1 1 1 1 KAPA Acetoacetic acid 1 1 1 1 70140 66951 67088 73327 Lactitol Lactitol 1 1 40725 1 3401429 3287732 3119931 3049856 L-Fucose 1-phosphate Fucose 1-phosphate 167828 158580 1 118010 256816 257697 269581 258448 L-Fuculose L-Fuculose 230575 244565 232421 240289 1 389347 387926 389187 L-Glutamic acid Glutamic acid 713395 663967 694216 710217 945261 860018 843335 861467 L-Histidine Histidine 1 1 106976 1 1 396687 265378 345856 L-Phenylalanine Phenylalanine 179760 165042 113144 1 43862 1 110795 57539 L-Tyrosine Tyrosine 4944478 4706057 4649312 4688136 3003869 2856764 2782012 2778962 L-Valine Valine 1 222238 1 215229 291980 272807 289796 289023 Myrsinone 80603 84479 294402 103906 1 256751 1 1 N-Acetyl-L-glutamic acid N-Acetyl-mannosamine 462328 384767 337820 322344 840478 610708 562100 497291 NAD NAD 1651536 1641600 1675607 1508159 1212336 1150226 1192866 1277399 NADH NADH 99971 74165 45248 1 195864 117456 75837 43006 NADPH NADPH 326335 278596 237913 176754 777539 533712 422414 348668 N-Glycolylneuraminic acid N-Glycolylneuraminic acid 1134581 906950 810308 828915 2344700 1823344 1557915 1432545 N-stearoyl taurine N-Stearoyl taurine 4536250 4592267 4824536 4634150 15772745 14904514 15387671 14795096 N-Succinyl-L-glutamate N2-Succinylglutamate 288909 245574 1 208751 255234 198841 1 1 Oleic acid (C18:1) Oleic acid 7134 1 36788 114592 97488 1 1 1 Oleoyl-CoA Oleoyl-CoA 1 1 1 1 15721 26657 18006 10401 OPC4-CoA OPC4-CoA 1241990 1085300 1017616 803991 1954619 1729258 1621982 1488719 O-Phospho-4-hydroxy-L-threonine O-Phospho-4-hydroxy-threonine 294093 236672 224987 186884 66917 1 1 1 Palmitic acid (C16:0) Palmitic acid 1 1 1 27599 33192 1 89375 85645 Pantoic acid (R)-Pantoic acid 829953 800741 795850 803497 1299527 1165060 1101323 1117130 Phosphoribulosylformimino-AICAR-P 51981 46400 47504 40337 1 1 1 22652 S-Acetylphosphopantetheine S-Acetylphosphopantetheine 1224252 1184693 1018278 497437 4460061 3815495 3849129 3456505 SAH / S-Adenosyl-L-homocysteine 514985 524562 492096 552293 258435 250696 245718 250974 Sedoheptulose 1_7-bisphosphate Sedoheptulose 1,7-bisphosphate 129921 109362 128178 1 359491 271265 311252 223881 Sorbitol-6-phosphate Pseudouridine 1 1 1 1 1 335372 299045 264984 Succinoadenosine Succinyladenosine 1 37894 1 1 196010 107669 84665 26293 Trehalose 6-phosphate Trehalose 6-phosphate 104472 93144 1 1 209170 141439 120395 107618 UDP-2_4-bis(acetamido)-2_4_6-trideoxy-beta-L-altropyranose 1 1 1 1 66537 73821 63033 59921 UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine 156593 190683 168168 1 400989 389558 369623 370221 UDPG / Uridine 5^-diphosphoglucose 6394396 5843365 5692712 5155392 15295039 13426593 12669815 12185931 UDP-L-Ara4FN UDP-4-deoxy-4-formamido-beta-L-arabinose 11385638 10439795 9899910 9102701 19388116 16943988 16119108 15220594 UDP-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-L-lysine 344479 299211 274864 267475 159511 118280 114457 97258 UDP / Uridine 5^-diphosphate 292948 297672 298891 310359 1 1 1 1 α-D-Glucose Glucose 1 894554 836392 1 1868234 1504132 935078 1 β-D-Fructose 1_6-bisphosphate Fructose 1,6-bisphosphate 407050 368710 331960 1 1 778903 776434 816316