Metabolite_name RefMet_name WL_HILIC_NEG_ifc_1 WL_HILIC_NEG_ifc_2 WL_HILIC_NEG_ifc_3 WL_HILIC_NEG_ifc_4 WL_HILIC_NEG_ifc_5 WL_HILIC_NEG_WT_1 WL_HILIC_NEG_WT_2 WL_HILIC_NEG_WT_3 WL_HILIC_NEG_WT_4 WL_HILIC_NEG_WT_5 Factors - Genotype:Knockout | Sample source:Whole Larvae Genotype:Knockout | Sample source:Whole Larvae Genotype:Knockout | Sample source:Whole Larvae Genotype:Knockout | Sample source:Whole Larvae Genotype:Knockout | Sample source:Whole Larvae Genotype:Wild-type | Sample source:Whole Larvae Genotype:Wild-type | Sample source:Whole Larvae Genotype:Wild-type | Sample source:Whole Larvae Genotype:Wild-type | Sample source:Whole Larvae Genotype:Wild-type | Sample source:Whole Larvae 2/3-PG 4972382 4731640 4738588 3139438 6324483 2875048 2550338 1940046 2851370 3197174 6-Phosphogluconic acid 6-Phosphogluconic acid 281328 225958 249168 178631 218974 271632 173877 153110 259241 232455 Aconitate trans-Aconitic acid 13232557 17344150 15644301 17911366 20649208 12378993 12427496 13216969 24081614 17353038 Adenine Adenine 16476203 14823735 15921752 14602692 11355252 52206084 51791212 38700560 40751160 33736368 ADP ADP 24661628 22039076 22540032 18761936 21390488 19139698 14371489 12858274 17487246 17052918 a-KG 2-Oxoglutaric acid 39250432 46009904 47715100 55099768 62986104 33576372 41105808 40766336 56577848 47686096 Alanine Alanine 151069088 148102400 155855520 144975808 166736464 152576528 157817600 147928496 195312144 176193888 AMP AMP 213472560 196293328 211318608 209088720 213423424 303616224 286119936 261324480 327575456 313469216 Arginine Arginine 110815600 96713680 100462600 81608136 103906992 93018256 87759976 76523840 101934720 91601488 Asparagine Asparagine 63954124 65484924 62377288 49054232 67578216 61223344 58213672 55062856 68886160 59043812 Aspartate Aspartic acid 24624244 23184952 22436616 17396618 18357138 18938438 17361946 17135504 15732642 12866094 ATP ATP 3312118 2736030 2819218 1796568 3487297 1354590 944504 834356 1336684 1039939 Citrate Citric acid 345995904 382549728 360204320 372447936 433066560 401645408 392863232 366632544 450848672 401976544 DHAP Dihydroxyacetone phosphate 642653 639217 660695 424566 938418 485012 389331 452666 624500 494311 FAD FAD 2352128 2106733 2413400 1817261 2756483 2731490 2649915 2411009 2810640 2412997 Fructose-bisphosphate Fructose 1,6-bisphosphate 592595 428944 436573 250852 495262 398338 310758 230704 410509 369046 Fumarate Fumaric acid 38787704 41869352 40791252 42520500 45543864 66441924 67648840 62906248 73228032 59112084 Gluconate Gluconic acid 73549432 73984792 66154168 42996284 59011864 33018062 31381026 27073778 34328528 37502072 Glucose Glucose 68964232 73849520 73270584 67098236 69160552 60371764 57895036 61638404 53402680 53816924 Glucose-6-phosphate Glucose 6-phosphate 213341392 180088080 203220656 185656688 201382464 189699648 175150640 168408528 212247088 208724240 Glutamate Glutamic acid 569432192 530808672 552301888 480074464 606459968 364468544 344294304 355488064 422397184 365526272 Glutamine Glutamine 371569088 382721440 370045984 282810496 419062752 279796768 267894592 250782112 303843200 254150304 Glutathione Glutathione 151859776 151299760 146128784 125279816 162622192 137747888 141461472 126013512 159667696 116162824 Glutathione_ oxidized Oxidized glutathione 590461 515991 517186 395735 419984 448260 370672 293557 346983 264156 Glycerol 3-phosphate sn-Glycero-3-phosphate 311892320 317801504 315135968 274590976 340962592 185773664 167372384 164554528 228222608 199037760 Glycine Glycine 15490151 14902291 14800931 11965879 13191878 10866370 10418561 12671627 10180559 9230180 Isoleucine Isoleucine 166440800 278610592 307868608 221625600 211656496 102145032 148952736 170383984 190706704 127284000 Lactate Lactic acid 1558859264 1466138112 1558577152 1549909248 1635084032 1820667136 1885712000 1697844480 1828337280 1990820992 Leucine Leucine 175854672 114589360 121745504 363600448 320666080 129076888 125734384 261975360 136002144 131711864 Lysine Lysine 19748784 20348644 19676354 13567196 19884514 13515924 13290924 11615638 14879620 13255645 Malate Malic acid 614096192 658213888 634738880 647661184 682715136 973887872 977918400 931896960 1052045504 868698816 Methionine Methionine 36509300 29424990 33960688 33753696 27690956 30203250 30539880 32314192 35910760 31428256 NAD NAD 7269626 6463837 6952030 7328879 7916512 10796759 10596752 8668649 11834088 9614821 NADH NADH 2107868 1742286 2029091 1307620 2534949 2700381 1959562 1451450 2545633 1914703 NADPH NADPH 523399 502638 511903 341241 486034 655801 545988 530349 589277 478769 Phenylalanine Phenylalanine 114550336 112490432 112282976 109503672 107717680 168050640 153785696 152609568 147564624 146416416 Phosphoenolpyruvate Phosphoenolpyruvic acid 186955 202809 211829 204288 388909 145273 163675 152855 215471 207921 Proline Proline 591293568 584489472 587373888 554899776 606629888 496029760 477944640 448740640 576244224 540356160 Pyruvate Pyruvic acid 75795600 92614416 92902968 92419440 120535416 90136560 108469640 90679392 135537168 121134232 Ribose-5-phosphate Ribose 5-phosphate 544287 660980 692213 680299 809439 651940 433752 599743 472537 588317 Ribulose-5-phosphate Ribulose 5-phosphate 754718 249646 778285 569297 381354 724126 326018 575137 271203 274405 Sedoheptulose 7-phosphate Sedoheptulose 7-phosphate 18726060 17885316 18860534 18687560 17764796 25495894 23961852 21577656 32810602 27946676 Serine Serine 24373358 22281050 23501476 18258446 25389750 19565970 18413790 22111544 25037630 20182396 Succinate Succinic acid 299368160 309094208 307720864 309724032 331684384 334267968 343217184 270159104 370888512 362578016 Threonine Threonine 120548552 93381968 103495392 66899680 94681624 49307012 45112060 47531656 41407672 40616448 Tyrosine Tyrosine 898784768 824117632 949566912 1065398464 1055201600 2455355392 2170336768 2149325312 2048419200 1923725184 UDP-N-acetylglucosamine UDP-N-acetylglucosamine 13317971 12287296 14007477 10688915 21590266 18846534 18802250 16431084 27072574 22884902 UMP UMP 3111713 3082369 3058718 2917545 3009174 6550380 5130187 6227417 7423256 5030959 Uridine 5^-diphosphoglucuronic acid UDP-glucuronic acid 315170 285837 292697 228966 282412 324975 331861 262293 309280 246689 Valine Valine 170729680 149108704 156488704 139301552 138327344 87129456 90074824 92874280 103075208 87895176 Xylulose-5-phosphate Xylulose 5-phosphate 3292868 2593090 2963969 2022793 3447758 4287582 3969395 3199786 4239224 4601813