Metabolite_name RefMet_name D E F A B C Factors - Factor:MCJ KO CART med | Sample source:T-Cells Factor:MCJ KO CART med | Sample source:T-Cells Factor:MCJ KO CART med | Sample source:T-Cells Factor:WT CART med | Sample source:T-Cells Factor:WT CART med | Sample source:T-Cells Factor:WT CART med | Sample source:T-Cells 5-10-Methenyltetrahydrofolate 5,10-Methenyl-THF 2326.0900 7652.7000 6786.3400 17884.0800 1984.0700 5-Oxoproline Pyroglutamic acid 12060173 12192916 8213134.5000 8317864 748918.0600 2611579 Acetylcholine Acetylcholine 459234.4700 533833.8800 540494.5000 341317.6600 165527.5500 300137.2200 acyl-C12:1 (O-dodecenoyl-carnitine) CAR 12:1 232325.0600 322816.8800 276151.2500 233369.1200 202824.5000 229522.1700 acyl-C14:1 (Tetradecenoyl Carnitine) CAR 14:1 18586.0100 81515.9800 56359.8700 111206.4100 21080.8000 27550.8100 acyl-C14 (O-tetradecanoyl-L-carnitine) CAR 14:0 24801.6300 61691.7200 96589.4300 80482.4300 15904.2500 52073.1700 acyl-C2 (acetyl-carnitine) CAR 2:0 5016.0600 5124.4500 3883.2900 2395.0800 acyl-C3 (propionyl-carnitine) CAR 3:0 151073 169809.1100 163341.3900 88985.5200 43960.7900 59945.2500 acyl-C4 (butanoyl-l-carnitine) CAR 4:0 54573.3700 59169.3100 56681.3500 31386.3700 11047.6600 21979.2400 acyl-C4-OH (Hydroxybutyrylcarnitine) CAR 4:0;OH 6528.4000 6092.7400 3931.4400 2786.4500 2465.6200 acyl-C5 (isovalerylcarnitine) CAR 4:0;3Me 171694.3000 211221.2700 125328.6200 115314.9100 25418.5400 46752.3300 acyl-C5-OH CAR 5:0;OH 3251.1300 3092 9224.3300 2651.6800 2306.6400 acyl-C6 (hexanoyl-l-carnitine) CAR 6:0 12565.7000 8557.7600 5302.2800 5888.4300 Adenosine Adenosine 972697.1900 587653.5000 675454.5600 744224.2500 90820.9800 263896.4100 Choline Choline 25780640 26762016 25263662 16901946 9498761 13981761 CMP CMP 347736.5000 321683.2800 330805.5900 245513.5000 179945.5800 221565.3300 Creatine Creatine 5077945.5000 5148315.5000 5679788.5000 4041169 3179826.7500 4313000.5000 Creatinine Creatinine 372297.3400 322271.1900 257966.9800 251845.6200 152382.9100 189605.1200 Cys-Gly Cys-Gly 591315.1200 574105.2500 599195.0600 259763.7300 119837.7500 195899.5600 Cytidine Cytidine 258058.4800 238843.3300 219376.1100 268586.6600 104568.4400 268844.1600 Cytosine Cytosine 691954.5000 834295.5600 873001.3100 755998.8100 471160.2800 811429.3100 gamma-L-Glutamyl-L-cysteine gamma-Glutamylcysteine 87423.6500 75943.6500 80581.5500 43406.3900 34799.0200 Glutathione disulfide Oxidized glutathione 125322.6500 183067.9500 215601.5500 308701.3400 68639.6600 239406.6400 GMP GMP 519133.2200 128707.7500 200740.3000 140813.7500 26505.2100 52639.2700 Guanidinoacetate Guanidoacetic acid 30042.4700 40801.7300 34055.3400 37512.1200 24503.6500 34844.2800 Hypotaurine Hypotaurine 195892.1200 196788.6900 131817.8600 256271.6900 258927.1900 317501.2800 Hypoxanthine Hypoxanthine 703927.4400 751096.1900 810906.7500 616633.3800 167498.8900 420965.5900 Indole-3-acetate Indoleacetic acid 295362.7500 436574.4700 747935.5000 356172.9700 150644.3900 288192.3800 kynurenine Kynurenine 4409.3700 6276.1700 14509.6300 10813.2100 3551.5900 4352.9000 L-alanine Alanine 2074696 1722981 1278456 2899601.2500 1423708 2347212.2500 L-arginine Arginine 4934806 4223950.5000 6972328 4378797.5000 2704065 4461140.5000 L-asparagine Asparagine 567966.3800 395946.4100 376895.3800 703490.3100 544056.4400 833265.6900 L-aspartate Aspartic acid 4871708 3764491.7500 2684774.2500 5977391.5000 5584386.5000 7831730.5000 L-Carnitine Carnitine 1923007.3800 1906532.3800 1680421.3800 1296800 312192.4700 798093.0600 L-Citrulline Citrulline 882434.2500 745029.5600 358113.5900 918793.5000 252538.5500 650328.6900 L-cysteine Cysteine 4655.7000 5678.7300 4048.8400 8091.4400 L-cystine Cystine 26954.0800 14206.5300 15569.7300 17054.7700 40252.6400 43958.9100 L-glutamate Glutamic acid 7319765.5000 6202989.5000 5458377.5000 6848666.5000 10564893 12352985 L-glutamine Glutamine 2399477.7500 2220893.2500 1995128 4403248.5000 2513811.7500 4662096 L-histidine Histidine 940233.3100 1038589.2500 901908 1053737.6200 319320.6200 526109.1900 L-leucine/L-isoleucine 23616624 26848600 26839890 18551056 5101423.5000 10462659 L-lysine Lysine 1772048 1616108.5000 1824667.5000 1556454.6200 723165 1213436.6200 L-methionine Methionine 3615653.2500 4054355 4977298.5000 2163834 655633.0600 1371486.6200 L-phenylalanine Phenylalanine 12300485 12438457 14553895 9279409 2495139.7500 5557782.5000 L-proline Proline 4483041.5000 4816232.5000 5357467.5000 3687341 1669128.5000 2985754.7500 L-serine Serine 2751616.7500 2296694.7500 1262677.8800 3460968.2500 1172575.5000 2322425.7500 L-threonine Threonine 1677710.3800 1276456 902260.4400 2266535 1505199.3800 2384315.7500 L-tryptophan Tryptophan 6331887.5000 5395861.5000 6540048.5000 4972201.5000 1271265.5000 2854987 L-tyrosine Tyrosine 12511029 12843873 14191539 9781055 2439037.7500 5448181.5000 L-valine Valine 9403460 10358271 9624791 7786622.5000 3211052.7500 4734124 NAD+ NAD 318612.5300 266344.3100 311710.5900 169119.9200 97853.3400 159148.1200 Nicotinamide Niacinamide 1599020 1582243.8800 1941346 50033.6100 41158.3200 31674.0400 Ornithine Ornithine 1649606.1200 1402677.3800 1003263.5000 1176229.3800 199346.0500 502341.0300 Pantothenol Pantothenol 488571.8800 542859.8100 635116.6200 411571.5000 172507.5600 313711.7800 Pyridoxal Pyridoxal 26285.3300 28834.7300 27215.2400 26197.5700 29369.7800 26379.7400 Spermidine Spermidine 7178412 789808.8100 430480.0900 160086.1700 62881.4700 168013.2300 Sphingosine Sphingosine 658386 1846358.6200 2768849.2500 3161847.7500 1051735 2036684.6200 Sphingosine 1-phosphate Sphingosine 1-phosphate 383647.8400 275147.6900 175304.2700 147247.8800 5067.2200 32281.6800 Taurine Taurine 6138257.5000 5176429.5000 4157402 5265075.5000 5270539 6398993.5000 Thymine Thymine 54683.9700 65031.5600 47290.6800 61353.9300 9672.7300 17846.9400 Uracil Uracil 101250.6200 151095.7300 192534.1700 141063.9800 43676.7800 104610.2700 Xanthine Xanthine 351033.3400 367374.0900 347689.1200 279047.4700 41528.8100 158168.9500