Metabolite_name RefMet_name R_L3A R_L3B R_L3C R_L3D R_L3E R_L4A R_L4B R_L4C R_L4D R_L4E R_L7A R_L7B R_L7C R_L7D R_L7E R_L8A R_L8B R_L8C R_L8D R_L8E Factors - Genotype:PHGDH+/- | Treatment:Control diet | Sample source:Mouse retina Genotype:PHGDH+/- | Treatment:Control diet | Sample source:Mouse retina Genotype:PHGDH+/- | Treatment:Control diet | Sample source:Mouse retina Genotype:PHGDH+/- | Treatment:Control diet | Sample source:Mouse retina Genotype:PHGDH+/- | Treatment:Control diet | Sample source:Mouse retina Genotype:PHGDH+/- | Treatment:Serine/glycine-depleted diet | Sample source:Mouse retina Genotype:PHGDH+/- | Treatment:Serine/glycine-depleted diet | Sample source:Mouse retina Genotype:PHGDH+/- | Treatment:Serine/glycine-depleted diet | Sample source:Mouse retina Genotype:PHGDH+/- | Treatment:Serine/glycine-depleted diet | Sample source:Mouse retina Genotype:PHGDH+/- | Treatment:Serine/glycine-depleted diet | Sample source:Mouse retina Genotype:Wild-type | Treatment:Control diet | Sample source:Mouse retina Genotype:Wild-type | Treatment:Control diet | Sample source:Mouse retina Genotype:Wild-type | Treatment:Control diet | Sample source:Mouse retina Genotype:Wild-type | Treatment:Control diet | Sample source:Mouse retina Genotype:Wild-type | Treatment:Control diet | Sample source:Mouse retina Genotype:Wild-type | Treatment:Serine/glycine-depleted diet | Sample source:Mouse retina Genotype:Wild-type | Treatment:Serine/glycine-depleted diet | Sample source:Mouse retina Genotype:Wild-type | Treatment:Serine/glycine-depleted diet | Sample source:Mouse retina Genotype:Wild-type | Treatment:Serine/glycine-depleted diet | Sample source:Mouse retina Genotype:Wild-type | Treatment:Serine/glycine-depleted diet | Sample source:Mouse retina Cer 18:1/16:0 Cer 18:1;O2/16:0 225.5062 284.0504 195.9975 220.6400 262.3347 264.2073 209.2723 222.9389 282.8071 300.8869 218.3249 264.5602 259.1482 238.9300 269.1016 294.0006 351.2621 260.1359 240.9111 258.4677 Cer 18:1/18:0 Cer 18:1;O2/18:0 117.4422 131.2817 110.0756 132.0011 113.3971 127.5466 110.8150 115.1874 107.5562 129.4593 95.6784 94.9803 122.3946 103.9295 102.2959 96.4345 151.1074 93.3554 115.6206 109.4212 Cer 18:1/20:0 Cer 18:1;O2/20:0 769.8451 586.6025 442.6335 692.9041 674.6728 580.4983 585.1882 589.9918 640.8876 714.2514 565.8714 585.0575 716.0143 594.2504 609.4637 602.5644 907.3166 657.9703 656.9647 459.8490 Cer 18:1/22:0 Cer 18:1;O2/22:0 666.0330 641.1423 400.8705 621.1110 640.8629 505.4283 518.5622 421.8772 547.6733 513.2726 514.8166 472.3893 657.9218 587.2575 636.0359 549.0173 707.0105 543.4927 638.3964 433.8120 Cer 18:1/24:0 Cer 18:1;O2/24:0 183.7785 221.3501 161.6819 161.1670 162.0196 109.8681 126.9535 125.6180 155.1827 157.2761 111.3505 166.7787 185.8313 194.8447 137.4997 117.4150 167.7752 172.3211 164.5941 134.5930 Cer 18:1/24:1 Cer 18:1;O2/24:1 343.4973 266.6570 194.1976 287.1918 273.6569 272.7104 282.6510 251.0657 252.0932 264.2075 247.7506 280.3061 337.2958 271.0365 267.4917 266.7019 367.9961 252.1139 292.5525 248.3124 DHCer 18:0/16:0 Cer 18:0;O2/16:0 1.9656 1.8368 2.4605 1.4831 1.4935 1.7544 1.4597 1.5184 1.8944 1.8725 1.7233 1.7326 1.7730 1.7559 1.8564 1.8239 1.8360 2.0260 1.8099 3.1043 DHCer 18:0/18:0 Cer 18:0;O2/18:0 1.4989 1.2339 1.1298 1.2284 0.9754 1.2932 1.1851 1.3353 1.4645 1.3387 1.1712 1.1879 1.3371 1.1021 1.1256 1.1770 1.1414 1.3152 1.2894 1.6981 DHCer 18:0/20:0 Cer 18:0;O2/20:0 1.7564 1.5191 1.4990 2.2217 1.2530 1.5516 1.5888 1.5828 1.4162 1.3737 1.3792 1.3859 1.5169 1.3250 1.2350 1.2897 1.4952 1.4846 1.5589 1.6868 DHCer 18:0/22:0 Cer 18:0;O2/22:0 0.3526 0.3103 0.3719 0.6606 0.2578 0.2254 0.2726 0.2568 0.2903 0.2552 0.3055 0.3275 0.2567 0.2580 0.2444 0.2566 0.2080 0.3100 0.2543 0.4239 DHCer 18:0/24:1 Cer 18:0;O2/24:1 0.2336 0.1820 0.1978 0.2431 0.2036 0.2213 0.1784 0.2561 0.2255 0.2059 0.2111 0.2008 0.3101 0.2315 0.2191 0.1893 0.1844 0.2358 0.2337 0.2311 doxDHCer 18:0/18:0 100.8256 79.4858 41.5387 84.8192 100.6280 222.5124 252.2231 254.6050 296.5729 315.3528 49.3231 68.9106 98.0602 59.5250 61.0986 185.5170 217.8257 193.9591 188.7197 140.2920 doxDHCer 18:0/20:0 151.3360 127.1344 81.8264 146.1682 165.6568 327.7798 376.0727 337.0798 374.5233 438.7608 90.6915 103.8243 141.4608 85.3833 100.6541 289.8905 277.8332 289.9470 277.1282 249.6857 doxDHCer 18:0/22:0 35.4383 36.3152 31.1703 32.0091 35.3743 61.3027 83.4250 55.4540 82.8965 108.5228 24.4028 30.7264 36.1735 24.2554 24.0298 43.9789 52.9184 62.9484 64.1269 60.6499 doxSA-C18:0 Spisulosine 0.1369 0.1140 0.1608 0.4015 0.1593 0.0206 0.0938 0.1551 0.3116 0.3138 0.0504 0.2044 0.0318 0.1715 0.1197 0.0166 0.2000 0.0196 0.2688 0.2100 Gluc/Gal-Cer 18:1/16:0 HexCer 18:1;O2/16:0 104.1211 85.4562 80.9843 91.4805 108.5888 86.8768 83.2638 84.0846 119.5871 107.4805 72.1262 76.5751 92.2087 95.2187 71.2720 89.0636 111.4160 114.1708 111.3022 85.7515 Gluc/Gal-Cer 18:1/18:0 HexCer 18:1;O2/18:0 17.0515 12.9375 14.5338 13.0041 12.5992 14.5817 11.0147 10.1821 12.0190 21.3306 11.7384 11.4320 11.7370 10.3479 9.2982 11.2772 12.1427 14.4189 11.3974 20.2196 Gluc/Gal-Cer 18:1/20:0 HexCer 18:1;O2/20:0 14.5299 9.8575 9.7820 7.5847 5.1778 6.7550 4.6048 6.9990 10.1301 19.3590 5.7086 9.2796 8.9382 12.5785 6.8113 5.5160 7.0503 9.6713 8.8040 12.3908 Gluc/Gal-Cer 18:1/22:0 HexCer 18:1;O2/22:0 66.6925 56.4196 41.0176 33.4855 29.4991 41.4452 25.5589 26.5238 50.4739 103.3409 26.1253 37.6437 41.2235 59.2434 31.6755 27.6154 39.7263 57.6360 51.4980 58.3794 Gluc/Gal-Cer 18:1/24:0 HexCer 18:1;O2/24:0 50.2078 20.8300 15.6017 10.6777 9.7840 17.6597 9.0300 9.1912 18.5504 105.4624 10.4076 17.6070 15.7506 28.2510 13.2709 8.0174 16.8097 22.4818 22.1381 85.5115 Gluc/Gal-Cer 18:1/24:1 HexCer 18:1;O2/24:1 35.1692 11.7231 10.0377 10.9267 9.0880 14.0169 8.5402 7.8048 11.4608 150.7368 14.0873 13.7339 13.2293 9.5250 10.2124 7.4995 12.7829 14.8988 24.5963 77.7174 Lact-Cer 18:1/16:0 LacCer 18:1;O2/16:0 23.9082 20.1946 19.8534 18.8509 25.5254 18.3874 19.5352 16.3242 21.4905 21.8400 19.0913 19.3092 23.2682 16.4565 18.1357 16.4757 23.5356 18.8920 22.8786 23.4844 Lact-Cer 18:1/18:0 LacCer 18:1;O2/18:0 19.4812 16.2005 14.5777 17.7355 19.6143 12.9285 12.8173 15.2783 14.9847 15.0427 15.5352 14.9673 16.6968 14.0738 13.8304 14.0181 17.3012 17.0772 16.1948 16.0092 SA-C18:0 Sphinganine 1.6474 1.3202 1.3366 1.7550 1.6568 1.6320 1.6551 1.1085 1.2378 1.4664 1.4819 1.2613 1.6776 1.2963 1.7022 1.5121 1.3391 1.3036 1.6587 1.5289 SM-C14:0 SM 18:1;O2/14:0 56.4790 51.6152 63.4273 50.0414 48.5755 56.1346 46.5433 39.4573 49.0600 48.5345 51.1425 60.3057 61.1066 49.7828 56.3060 40.5436 55.9782 48.7686 56.8386 70.0269 SM-C16:0 SM 18:1;O2/16:0 3585.2226 3449.8071 4066.3284 3432.5169 3123.5145 3393.6177 2991.4799 2858.4837 3512.2349 3416.8171 3296.4510 3297.1060 3569.9487 3078.3693 3306.0193 2759.6113 3568.3792 3283.9427 3383.2924 4442.2663 SM-C18:0 SM 18:1;O2/18:0 893.3265 866.6036 919.1241 925.2160 783.1063 887.5058 734.5335 741.5581 849.8667 844.3555 809.6784 844.8160 855.5289 770.2306 798.2488 725.5822 929.9073 836.2976 843.1475 969.7936 SM-C18:1 SM 18:1;O2/18:1 880.9227 845.1179 868.6877 921.3274 870.0925 903.2241 784.0963 770.1114 883.9234 852.3677 810.7659 555.9647 895.8025 743.0263 821.6457 786.0908 1000.5711 900.1459 906.1265 1010.1156 SM-C20:0 SM 18:1;O2/20:0 609.1434 619.9345 601.3799 623.3916 519.4005 566.8574 457.1240 445.0692 550.6055 534.0862 512.9734 584.4275 579.3956 532.1938 538.2808 476.9113 626.6309 523.7733 556.7242 601.0104 SM-C20:1 SM 18:1;O2/20:1 137.8346 144.0569 112.1763 120.8913 100.8173 119.4596 94.9721 98.9262 131.7294 123.0547 105.5214 99.8112 125.6921 119.6306 123.3149 99.4250 129.2363 122.6842 118.4458 133.8229 SM-C22:0 SM 18:1;O2/22:0 2007.1354 1920.7084 1724.8741 1735.5131 1408.9226 1706.3631 1339.4514 1366.8906 1928.1821 1852.9879 1485.8292 1834.0167 1826.0527 1634.1188 1676.3824 1441.3692 1960.0150 1729.2022 1793.1804 1857.2752 SM-C22:1 SM 18:1;O2/22:1 429.6196 446.6471 354.6661 337.5094 275.7216 365.7497 282.8686 297.8065 458.5693 411.0617 306.9963 343.3564 408.9864 366.1500 376.9564 306.5970 423.0025 402.0431 388.2345 430.7866 SM-C24:0 SM 18:1;O2/24:0 734.9307 766.7462 715.9899 521.6782 391.7820 592.1430 438.6953 471.6884 719.0881 822.4444 511.9439 809.3422 666.5039 652.3535 558.8191 440.8263 676.7914 626.4667 635.5752 844.1048 SM-C24:1 SM 18:1;O2/24:1 844.2937 715.6151 804.0629 695.6310 633.2288 668.3802 625.2068 609.8192 711.9899 813.4097 674.0071 757.4641 814.3289 728.7972 656.2628 562.8237 806.6412 704.9301 735.9107 921.7398 SO-C18:1 Sphingosine 30.1663 27.2973 26.8002 27.4673 28.8366 18.6088 23.3564 20.8840 25.2779 27.6927 26.5887 21.7538 22.1218 28.4162 24.6896 24.8923 28.8399 25.7808 27.3753 19.7945