Metabolite_name RefMet_name CD_A549_3_1_IPI3_rep1 CD_A549_3_1_IPI3_rep2 CD_A549_3_1_IPI3_rep3 CD_A549_3_1_NIV3_rep1 CD_A549_3_1_NIV3_rep3 CD_A549_TW_NIV2_rep2 CD_A549_3_1_CTL3_rep1 CD_A549_3_1_CTL3_rep3 CD_A549_TW_CTL2_rep2 CD_A549_TW_IPI3_rep1 CD_A549_TW_IPI3_rep2 CD_A549_TW_IPI3_rep3 CD_A549_NIV2_rep2 CD_A549_TW_NIV3_rep1 CD_A549_TW_NIV3_rep3 CD_A549_CTL2_rep2 CD_A549_TW_CTL3_rep1 CD_A549_TW_CTL3_rep3 CD_A549_IPI3_rep1 CD_A549_IPI3_rep2 CD_A549_IPI3_rep3 CD_A549_3_1_NIV2_rep2 CD_A549_NIV3_rep1 CD_A549_NIV3_rep3 CD_A549_3_1_CTL2_rep2 CD_A549_CTL3_rep1 CD_A549_CTL3_rep3 CD_H292_TW_IPI1_rep1 CD_H292_TW_IPI1_rep2 CD_H292_TW_IPI1_rep3 CD_H292_TW_NIV1_rep1 CD_H292_TW_NIV1_rep2 CD_H292_TW_NIV1_rep3 CD_H292_TW_CTL1_rep1 CD_H292_TW_CTL1_rep2 CD_H292_TW_CTL1_rep3 CD_H292_IPI1_rep1 CD_H292_IPI1_rep2 CD_H292_IPI1_rep3 CD_H292_NIV1_rep1 CD_H292_NIV1_rep2 CD_H292_NIV1_rep3 CD_H292_CTL1_rep1 CD_H292_CTL1_rep2 CD_H292_CTL1_rep3 CD_H292_3_1_IPI1_rep1 CD_H292_3_1_IPI1_rep2 CD_H292_3_1_IPI1_rep3 CD_H292_3_1_NIV1_rep1 CD_H292_3_1_NIV1_rep2 CD_H292_3_1_NIV1_rep3 CD_H292_3_1_CTL1_rep1 CD_H292_3_1_CTL1_rep2 CD_H292_3_1_CTL1_rep3 CD_PC9_3_1_IPI1_rep1 CD_PC9_3_1_IPI1_rep2 CD_PC9_3_1_IPI1_rep3 CD_PC9_NIV1_rep1 CD_PC9_NIV1_rep2 CD_PC9_NIV1_rep3 CD_PC9_CTL1_rep1 CD_PC9_CTL1_rep2 CD_PC9_CTL1_rep3 CD_PC9_TW_IPI1_rep1 CD_PC9_TW_IPI1_rep2 CD_PC9_TW_IPI1_rep3 CD_PC9_TW_NIV1_rep1 CD_PC9_TW_NIV1_rep2 CD_PC9_TW_NIV1_rep3 CD_PC9_TW_CTL1_rep1 CD_PC9_TW_CTL3_rep CD_PC9_TW_CTL3_rep3 CD_PC9_IPI3_rep1 CD_PC9_IPI3_rep2 CD_PC9_IPI3_rep3 CD_PC9_3_1_NIV1_rep1 CD_PC9_3_1_NIV1_rep2 CD_PC9_3_1_NIV1_rep3 CD_PC9_3_1_CTL1_rep1 CD_PC9_3_1_CTL1_rep2 CD_PC9_3_1_CTL1_rep3 Factors - Sample source:Non-small cell lung cancer cells | Cell line:A549 | Culture Type:Direct Co-culture | Immune checkpoint inhibitor:Ipilimumab Sample source:Non-small cell lung cancer cells | Cell line:A549 | Culture Type:Direct Co-culture | Immune checkpoint inhibitor:Ipilimumab Sample source:Non-small cell lung cancer cells | Cell line:A549 | Culture Type:Direct Co-culture | Immune checkpoint inhibitor:Ipilimumab Sample source:Non-small cell lung cancer cells | Cell line:A549 | Culture Type:Direct Co-culture | Immune checkpoint inhibitor:Nivolumab Sample source:Non-small cell lung cancer cells | Cell line:A549 | Culture Type:Direct Co-culture | Immune checkpoint inhibitor:Nivolumab Sample source:Non-small cell lung cancer cells | Cell line:A549 | Culture Type:Direct Co-culture | Immune checkpoint inhibitor:Nivolumab Sample source:Non-small cell lung cancer cells | Cell line:A549 | Culture Type:Direct Co-culture | Immune checkpoint inhibitor:No treatment Sample source:Non-small cell lung cancer cells | Cell line:A549 | Culture Type:Direct Co-culture | Immune checkpoint inhibitor:No treatment Sample source:Non-small cell lung cancer cells | Cell line:A549 | Culture Type:Direct Co-culture | Immune checkpoint inhibitor:No treatment Sample source:Non-small cell lung cancer cells | Cell line:A549 | Culture Type:Indirect Co-culture | Immune checkpoint inhibitor:Ipilimumab Sample source:Non-small cell lung cancer cells | Cell line:A549 | Culture Type:Indirect Co-culture | Immune checkpoint inhibitor:Ipilimumab Sample source:Non-small cell lung cancer cells | Cell line:A549 | Culture Type:Indirect Co-culture | Immune checkpoint inhibitor:Ipilimumab Sample source:Non-small cell lung cancer cells | Cell line:A549 | Culture Type:Indirect Co-culture | Immune checkpoint inhibitor:Nivolumab Sample source:Non-small cell lung cancer cells | Cell line:A549 | Culture Type:Indirect Co-culture | Immune checkpoint inhibitor:Nivolumab Sample source:Non-small cell lung cancer cells | Cell line:A549 | Culture Type:Indirect Co-culture | Immune checkpoint inhibitor:Nivolumab Sample source:Non-small cell lung cancer cells | Cell line:A549 | Culture Type:Indirect Co-culture | Immune checkpoint inhibitor:No treatment Sample source:Non-small cell lung cancer cells | Cell line:A549 | Culture Type:Indirect Co-culture | Immune checkpoint inhibitor:No treatment Sample source:Non-small cell lung cancer cells | Cell line:A549 | Culture Type:Indirect Co-culture | Immune checkpoint inhibitor:No treatment Sample source:Non-small cell lung cancer cells | Cell line:A549 | Culture Type:Monoculture | Immune checkpoint inhibitor:Ipilimumab Sample source:Non-small cell lung cancer cells | Cell line:A549 | Culture Type:Monoculture | Immune checkpoint inhibitor:Ipilimumab Sample source:Non-small cell lung cancer cells | Cell line:A549 | Culture Type:Monoculture | Immune checkpoint inhibitor:Ipilimumab Sample source:Non-small cell lung cancer cells | Cell line:A549 | Culture Type:Monoculture | Immune checkpoint inhibitor:Nivolumab Sample source:Non-small cell lung cancer cells | Cell line:A549 | Culture Type:Monoculture | Immune checkpoint inhibitor:Nivolumab Sample source:Non-small cell lung cancer cells | Cell line:A549 | Culture Type:Monoculture | Immune checkpoint inhibitor:Nivolumab Sample source:Non-small cell lung cancer cells | Cell line:A549 | Culture Type:Monoculture | Immune checkpoint inhibitor:No treatment Sample source:Non-small cell lung cancer cells | Cell line:A549 | Culture Type:Monoculture | Immune checkpoint inhibitor:No treatment Sample source:Non-small cell lung cancer cells | Cell line:A549 | Culture Type:Monoculture | Immune checkpoint inhibitor:No treatment Sample source:Non-small cell lung cancer cells | Cell line:H292 | Culture Type:Direct Co-culture | Immune checkpoint inhibitor:Ipilimumab Sample source:Non-small cell lung cancer cells | Cell line:H292 | Culture Type:Direct Co-culture | Immune checkpoint inhibitor:Ipilimumab Sample source:Non-small cell lung cancer cells | Cell line:H292 | Culture Type:Direct Co-culture | Immune checkpoint inhibitor:Ipilimumab Sample source:Non-small cell lung cancer cells | Cell line:H292 | Culture Type:Direct Co-culture | Immune checkpoint inhibitor:Nivolumab Sample source:Non-small cell lung cancer cells | Cell line:H292 | Culture Type:Direct Co-culture | Immune checkpoint inhibitor:Nivolumab Sample source:Non-small cell lung cancer cells | Cell line:H292 | Culture Type:Direct Co-culture | Immune checkpoint inhibitor:Nivolumab Sample source:Non-small cell lung cancer cells | Cell line:H292 | Culture Type:Direct Co-culture | Immune checkpoint inhibitor:No treatment Sample source:Non-small cell lung cancer cells | Cell line:H292 | Culture Type:Direct Co-culture | Immune checkpoint inhibitor:No treatment Sample source:Non-small cell lung cancer cells | Cell line:H292 | Culture Type:Direct Co-culture | Immune checkpoint inhibitor:No treatment Sample source:Non-small cell lung cancer cells | Cell line:H292 | Culture Type:Indirect Co-culture | Immune checkpoint inhibitor:Ipilimumab Sample source:Non-small cell lung cancer cells | Cell line:H292 | Culture Type:Indirect Co-culture | Immune checkpoint inhibitor:Ipilimumab Sample source:Non-small cell lung cancer cells | Cell line:H292 | Culture Type:Indirect Co-culture | Immune checkpoint inhibitor:Ipilimumab Sample source:Non-small cell lung cancer cells | Cell line:H292 | Culture Type:Indirect Co-culture | Immune checkpoint inhibitor:Nivolumab Sample source:Non-small cell lung cancer cells | Cell line:H292 | Culture Type:Indirect Co-culture | Immune checkpoint inhibitor:Nivolumab Sample source:Non-small cell lung cancer cells | Cell line:H292 | Culture Type:Indirect Co-culture | Immune checkpoint inhibitor:Nivolumab Sample source:Non-small cell lung cancer cells | Cell line:H292 | Culture Type:Indirect Co-culture | Immune checkpoint inhibitor:No treatment Sample source:Non-small cell lung cancer cells | Cell line:H292 | Culture Type:Indirect Co-culture | Immune checkpoint inhibitor:No treatment Sample source:Non-small cell lung cancer cells | Cell line:H292 | Culture Type:Indirect Co-culture | Immune checkpoint inhibitor:No treatment Sample source:Non-small cell lung cancer cells | Cell line:H292 | Culture Type:Monoculture | Immune checkpoint inhibitor:Ipilimumab Sample source:Non-small cell lung cancer cells | Cell line:H292 | Culture Type:Monoculture | Immune checkpoint inhibitor:Ipilimumab Sample source:Non-small cell lung cancer cells | Cell line:H292 | Culture Type:Monoculture | Immune checkpoint inhibitor:Ipilimumab Sample source:Non-small cell lung cancer cells | Cell line:H292 | Culture Type:Monoculture | Immune checkpoint inhibitor:Nivolumab Sample source:Non-small cell lung cancer cells | Cell line:H292 | Culture Type:Monoculture | Immune checkpoint inhibitor:Nivolumab Sample source:Non-small cell lung cancer cells | Cell line:H292 | Culture Type:Monoculture | Immune checkpoint inhibitor:Nivolumab Sample source:Non-small cell lung cancer cells | Cell line:H292 | Culture Type:Monoculture | Immune checkpoint inhibitor:No treatment Sample source:Non-small cell lung cancer cells | Cell line:H292 | Culture Type:Monoculture | Immune checkpoint inhibitor:No treatment Sample source:Non-small cell lung cancer cells | Cell line:H292 | Culture Type:Monoculture | Immune checkpoint inhibitor:No treatment Sample source:Non-small cell lung cancer cells | Cell line:PC-9 | Culture Type:Direct Co-culture | Immune checkpoint inhibitor:Ipilimumab Sample source:Non-small cell lung cancer cells | Cell line:PC-9 | Culture Type:Direct Co-culture | Immune checkpoint inhibitor:Ipilimumab Sample source:Non-small cell lung cancer cells | Cell line:PC-9 | Culture Type:Direct Co-culture | Immune checkpoint inhibitor:Ipilimumab Sample source:Non-small cell lung cancer cells | Cell line:PC-9 | Culture Type:Direct Co-culture | Immune checkpoint inhibitor:Nivolumab Sample source:Non-small cell lung cancer cells | Cell line:PC-9 | Culture Type:Direct Co-culture | Immune checkpoint inhibitor:Nivolumab Sample source:Non-small cell lung cancer cells | Cell line:PC-9 | Culture Type:Direct Co-culture | Immune checkpoint inhibitor:Nivolumab Sample source:Non-small cell lung cancer cells | Cell line:PC-9 | Culture Type:Direct Co-culture | Immune checkpoint inhibitor:No treatment Sample source:Non-small cell lung cancer cells | Cell line:PC-9 | Culture Type:Direct Co-culture | Immune checkpoint inhibitor:No treatment Sample source:Non-small cell lung cancer cells | Cell line:PC-9 | Culture Type:Direct Co-culture | Immune checkpoint inhibitor:No treatment Sample source:Non-small cell lung cancer cells | Cell line:PC-9 | Culture Type:Indirect Co-culture | Immune checkpoint inhibitor:Ipilimumab Sample source:Non-small cell lung cancer cells | Cell line:PC-9 | Culture Type:Indirect Co-culture | Immune checkpoint inhibitor:Ipilimumab Sample source:Non-small cell lung cancer cells | Cell line:PC-9 | Culture Type:Indirect Co-culture | Immune checkpoint inhibitor:Ipilimumab Sample source:Non-small cell lung cancer cells | Cell line:PC-9 | Culture Type:Indirect Co-culture | Immune checkpoint inhibitor:Nivolumab Sample source:Non-small cell lung cancer cells | Cell line:PC-9 | Culture Type:Indirect Co-culture | Immune checkpoint inhibitor:Nivolumab Sample source:Non-small cell lung cancer cells | Cell line:PC-9 | Culture Type:Indirect Co-culture | Immune checkpoint inhibitor:Nivolumab Sample source:Non-small cell lung cancer cells | Cell line:PC-9 | Culture Type:Indirect Co-culture | Immune checkpoint inhibitor:No treatment Sample source:Non-small cell lung cancer cells | Cell line:PC-9 | Culture Type:Indirect Co-culture | Immune checkpoint inhibitor:No treatment Sample source:Non-small cell lung cancer cells | Cell line:PC-9 | Culture Type:Indirect Co-culture | Immune checkpoint inhibitor:No treatment Sample source:Non-small cell lung cancer cells | Cell line:PC-9 | Culture Type:Monoculture | Immune checkpoint inhibitor:Ipilimumab Sample source:Non-small cell lung cancer cells | Cell line:PC-9 | Culture Type:Monoculture | Immune checkpoint inhibitor:Ipilimumab Sample source:Non-small cell lung cancer cells | Cell line:PC-9 | Culture Type:Monoculture | Immune checkpoint inhibitor:Ipilimumab Sample source:Non-small cell lung cancer cells | Cell line:PC-9 | Culture Type:Monoculture | Immune checkpoint inhibitor:Nivolumab Sample source:Non-small cell lung cancer cells | Cell line:PC-9 | Culture Type:Monoculture | Immune checkpoint inhibitor:Nivolumab Sample source:Non-small cell lung cancer cells | Cell line:PC-9 | Culture Type:Monoculture | Immune checkpoint inhibitor:Nivolumab Sample source:Non-small cell lung cancer cells | Cell line:PC-9 | Culture Type:Monoculture | Immune checkpoint inhibitor:No treatment Sample source:Non-small cell lung cancer cells | Cell line:PC-9 | Culture Type:Monoculture | Immune checkpoint inhibitor:No treatment Sample source:Non-small cell lung cancer cells | Cell line:PC-9 | Culture Type:Monoculture | Immune checkpoint inhibitor:No treatment Acetate Acetic acid 0.2099 0.3110 0.2444 0.6084 0.4126 0.5314 0.5038 0.6180 0.3499 0.4671 0.4133 0.4133 1.7881 1.9696 1.0971 1.1826 1.3464 2.3384 0.7700 0.4694 0.8694 1.5238 1.5356 2.1084 1.4439 1.2335 1.3550 0.2587 0.1254 0.1152 0.4587 0.2525 0.3769 0.8641 1.3927 1.3043 0.3514 0.3182 0.2570 1.8406 1.1120 1.4837 1.2322 1.3207 1.4220 0.5988 0.5920 0.4813 1.8166 2.1626 1.9989 0.8013 0.6294 1.1696 0.0459 0.0467 0.0710 0.0506 0.0388 0.0470 0.0968 0.0518 0.0476 0.2186 0.2378 0.1981 0.1863 0.2172 0.2366 0.1594 0.1898 0.1623 0.1928 0.2755 0.1545 0.2212 0.2424 0.2267 0.2873 0.2657 0.2267 Alanine Alanine 0.1583 0.1946 0.1578 0.1765 0.1414 0.1535 0.1433 0.1206 0.1887 0.3687 0.2291 0.2910 0.3640 0.2615 0.3440 0.2285 0.2768 0.3579 0.3934 0.3740 0.3740 0.3850 0.2713 0.3466 0.2761 0.3284 0.3788 0.3086 0.2746 0.2628 0.1086 0.0655 0.1018 0.3887 0.2194 0.3670 0.2639 0.2178 0.2439 0.3632 0.3400 0.3249 0.2559 0.2059 0.2182 0.2636 0.1634 0.1928 0.3694 0.3741 0.3916 0.3032 0.2146 0.2024 0.1475 0.1243 0.1515 0.1214 0.1315 0.1339 0.1432 0.1251 0.1383 0.4010 0.3171 0.3951 0.3880 0.3493 0.3076 0.3120 0.3019 0.2967 0.3069 0.3243 0.2561 0.2988 0.2546 0.2785 0.4009 0.3488 0.3335 Arginine Arginine 0.2534 0.6611 0.2644 0.2275 0.2753 2.1883 0.1983 0.2127 0.6607 0.5632 0.5364 0.5364 0.8599 0.7590 0.5243 0.5859 0.5134 0.7283 0.7557 0.6928 0.6928 0.4040 0.7242 1.2303 0.4366 0.4807 0.4886 0.2494 0.1414 0.1499 0.2494 0.1101 0.1150 0.2947 0.2306 0.2119 0.7045 0.6699 0.6567 0.5368 0.5243 0.5572 0.6956 0.6222 0.6477 0.6507 0.5961 0.5660 0.6129 0.6702 0.6317 0.3777 0.3654 0.3521 0.4998 0.4367 0.4575 0.4077 0.4070 0.4229 0.4099 0.4012 0.4256 0.4429 0.4494 0.4949 0.4898 0.4847 0.4958 0.4008 0.4167 0.4050 0.5039 0.5114 0.5177 0.3750 0.3815 0.4045 0.3957 0.2933 0.3014 Aspartate Aspartic acid 0.1064 0.1754 0.1102 0.1012 0.0995 0.1488 0.0846 0.0742 0.0616 0.2278 0.2507 0.2507 0.1443 0.0916 0.0777 0.1557 0.1879 0.2375 0.2028 0.1511 0.1511 0.1920 0.1366 0.1728 0.2369 0.1041 0.1673 0.0306 0.0304 0.0286 0.0106 0.0176 0.0192 0.0339 0.0290 0.0286 0.0597 0.0365 0.0405 0.0530 0.0599 0.0592 0.0703 0.0665 0.0857 0.1068 0.0906 0.0808 0.0655 0.0544 0.0627 0.0654 0.0586 0.0649 0.0410 0.0351 0.0361 0.0402 0.0331 0.0311 0.0270 0.0215 0.0227 0.0610 0.0325 0.0611 0.0321 0.0389 0.0300 0.0343 0.0378 0.0262 0.0355 0.0301 0.0292 0.0383 0.0385 0.0411 0.0271 0.0297 0.0265 Choline Choline 0.1374 0.2403 0.2403 0.2663 0.2365 0.2365 0.1724 0.2089 0.1780 0.1585 0.1143 0.4300 0.4085 0.1182 0.2725 0.1485 0.2126 0.1423 0.2583 0.1603 0.1603 0.1834 0.1803 0.1981 0.1633 0.0974 0.1704 0.0233 0.0277 0.0269 0.0333 0.0115 0.0307 0.0309 0.0344 0.0262 0.0906 0.0508 0.0595 0.0260 0.0357 0.0439 0.0419 0.0334 0.0388 0.0595 0.0645 0.0544 0.0227 0.0340 0.0281 0.0680 0.0604 0.0486 0.0663 0.0554 0.0641 0.0791 0.0611 0.0667 0.0730 0.0863 0.0755 0.1439 0.0647 0.1318 0.0714 0.0668 0.0705 0.0513 0.0664 0.0604 0.0582 0.0693 0.0476 0.0626 0.0585 0.0602 0.0657 0.0626 0.0609 Cystine Cystine 0.1724 0.2071 0.1828 0.1682 0.1458 0.2645 0.1956 0.1793 0.1591 0.1428 0.3547 0.1547 0.1302 0.1533 0.1662 0.1718 0.1291 0.1927 0.2215 0.2432 0.2432 0.1469 0.1633 0.1501 0.1387 0.1509 0.1943 0.1201 0.1067 0.0964 0.0701 0.0689 0.0748 0.2442 0.1832 0.1650 0.2409 0.1717 0.1932 0.1005 0.1186 0.1113 0.2065 0.2228 0.1962 0.2513 0.2329 0.1809 0.1025 0.1132 0.1020 0.1416 0.1409 0.1351 0.1170 0.0990 0.1131 0.1284 0.1321 0.1116 0.1081 0.0605 0.1405 0.1479 0.1300 0.1115 0.1424 0.1302 0.1734 0.0952 0.0996 0.0954 0.1106 0.1002 0.0981 0.0954 0.0939 0.0886 0.1312 0.1231 0.1211 Formate Formic acid 0.0337 0.0311 0.0311 0.0491 0.0698 0.0698 0.0358 0.0635 0.0174 0.0409 0.0884 0.0884 0.0750 0.9740 0.0391 0.0388 0.0548 0.0708 0.0364 0.0352 0.0352 0.0142 0.0301 0.0905 0.0431 0.0328 0.0860 0.6395 0.0779 0.0607 0.0395 0.0381 0.0819 0.1391 0.1401 0.1929 0.0591 0.0731 0.0540 0.1849 0.1868 0.1847 0.2205 0.1682 0.2129 0.1029 0.1421 0.0863 0.1760 0.2155 0.2387 0.2076 0.1415 0.2235 0.0549 0.0454 0.0488 0.0385 0.0353 0.0402 0.0498 0.0434 0.0461 0.0425 0.0443 0.0405 0.0584 0.0551 0.0448 0.0348 0.0469 0.0433 0.0496 0.0437 0.0385 0.0378 0.0358 0.0442 0.0464 0.0425 0.0446 Fumarate Fumaric acid 0.0052 0.0031 0.0034 0.0052 0.0031 0.0034 0.0087 0.0098 0.0070 0.0061 0.0064 0.0056 0.0034 0.0053 0.0048 0.0030 0.0035 0.0031 0.0009 0.0002 0.0035 0.0036 0.0055 0.0034 0.0019 0.0018 0.0026 0.0077 0.0057 0.0075 0.0059 0.0068 0.0077 0.0068 0.0057 0.0072 0.0035 0.0050 0.0044 0.0045 0.0046 0.0059 0.0060 0.0066 0.0041 0.0059 0.0061 0.0067 0.0058 0.0063 0.0059 0.0050 0.0048 0.0052 Glucose Glucose 18.3623 23.4488 23.4488 12.8466 18.4319 18.4319 20.0690 21.2185 22.5498 19.0104 17.5671 17.5671 19.1707 11.8337 11.0591 19.6902 19.0821 19.0254 14.4246 18.2226 18.2226 14.3495 14.0364 14.9583 15.9010 15.1387 18.8249 22.9014 23.6338 24.9567 21.9014 19.1659 23.2583 22.9634 23.6772 23.8429 23.0666 23.4005 24.5027 22.5466 22.7749 22.2399 22.3231 23.5251 25.3261 21.6675 22.7994 22.7959 22.7441 24.7188 24.0764 22.4173 23.8724 23.1070 24.2620 24.4015 24.4777 24.8999 24.2927 24.4845 24.6501 24.4914 24.3826 24.6877 24.6194 24.6046 25.1198 24.0046 23.8875 25.8079 24.1518 23.9512 25.9445 23.7473 21.1693 24.1861 24.2531 24.2819 25.4447 24.4587 24.4259 Glutamate Glutamic acid 0.0987 0.0926 0.1170 0.0819 0.1410 0.1353 0.1092 0.0975 0.1415 0.3054 0.2750 0.2750 0.3018 0.3626 0.3854 0.2994 0.3236 0.3283 0.2682 0.2523 0.2523 0.2016 0.2534 0.2943 0.1460 0.1439 0.1145 0.2393 0.1708 0.1558 0.2393 0.1224 0.1492 0.3423 0.3484 0.3511 0.2439 0.2214 0.2104 0.3104 0.3172 0.3274 0.4171 0.4316 0.4106 0.3157 0.2559 0.2145 0.3327 0.2901 0.2928 0.2520 0.1450 0.1916 0.2333 0.1556 0.1601 0.2354 0.1618 0.1813 0.2047 0.2070 0.1949 0.2291 0.1930 0.2167 0.2416 0.2542 0.2180 0.1633 0.1922 0.1746 0.1338 0.1471 0.1305 0.1459 0.1312 0.1640 0.2477 0.1804 0.1656 Glutamine Glutamine 0.6642 0.8429 0.7372 0.4662 0.4361 0.4402 0.2861 0.2906 0.3456 1.5023 1.2275 1.2275 0.3734 0.3299 0.3814 0.5047 0.4995 0.5954 1.8508 1.4276 1.4276 0.1488 1.0946 0.9664 1.5058 1.3381 1.4980 2.0053 1.8872 1.8793 2.0053 1.9122 1.8630 1.5594 1.5115 1.0114 1.6725 1.6814 1.8848 1.2748 1.2648 1.4059 1.6834 1.5864 1.8080 1.9633 1.9587 1.7079 1.3849 1.4978 1.4625 1.8103 1.8936 1.8241 1.6690 1.7209 1.6989 1.7009 1.6575 1.6334 1.5268 1.6097 1.6434 1.7294 1.6357 1.6885 1.8825 1.6685 1.7186 1.4120 1.5451 1.4694 1.4827 1.4590 1.4097 1.6754 1.6929 1.6558 1.7914 1.7277 1.7437 Glycine Glycine 0.2880 0.2706 0.2802 0.3095 0.3196 0.3990 0.2902 0.2695 0.2028 0.6107 0.8538 0.7538 0.6497 0.6760 0.5391 0.5217 0.6463 0.6850 0.5161 0.4799 0.4799 0.4961 0.4826 0.5768 0.5801 0.4899 0.5242 0.2380 0.2306 0.2485 0.1380 0.1660 0.0509 0.3788 0.3857 0.4882 0.7281 0.7233 0.7481 0.1057 0.1167 0.1233 0.3169 0.2148 0.3169 0.6417 0.5229 0.7674 0.2511 0.3581 0.3466 0.3320 0.4401 0.4480 0.1805 0.1886 0.1987 0.2547 0.2481 0.2597 0.1866 0.2132 0.2514 0.3377 0.3141 0.3793 0.1988 0.1904 0.1738 0.2034 0.2508 0.2541 0.2619 0.2580 0.2644 0.5430 0.6430 0.6389 0.4305 0.6558 0.4357 Histidine Histidine 0.1553 0.1469 0.1588 0.1460 0.1660 0.1150 0.1417 0.1418 0.1140 0.1340 0.0966 0.0966 0.1642 0.1302 0.1675 0.1150 0.0921 0.1475 0.1585 0.1423 0.1423 0.1256 0.1183 0.1741 0.1101 0.1454 0.1438 0.1512 0.2349 0.2117 0.1512 0.0877 0.1533 0.3789 0.2260 0.2268 0.3343 0.2041 0.2108 0.2003 0.2070 0.2211 0.3137 0.2187 0.2449 0.3755 0.2876 0.2251 0.2409 0.2645 0.2507 0.2927 0.3177 0.2629 0.3129 0.2539 0.2658 0.1802 0.2047 0.2361 0.2800 0.2439 0.2473 0.3128 0.2453 0.3226 0.3408 0.2605 0.2690 0.2605 0.2574 0.2217 0.3329 0.2738 0.2051 0.2294 0.2143 0.2264 0.2845 0.2345 0.2417 Isoleucine Isoleucine 0.4756 0.4636 0.3054 0.6597 0.6383 0.5957 0.5216 0.4206 0.4402 0.6226 0.9244 0.9244 0.7884 0.4027 0.5099 0.8611 0.8135 0.9683 0.8509 0.6091 0.6091 0.7176 0.4992 0.9903 1.0131 0.6230 0.6704 0.9281 1.1365 0.8350 0.9281 0.4699 0.8879 0.8430 0.8677 0.5692 1.2595 0.9721 0.9832 0.7242 0.8213 0.8770 1.0131 0.9304 1.0308 1.4737 1.2572 1.0629 0.9258 0.9554 0.9889 1.1401 1.3781 1.1318 1.3719 1.0387 1.1089 0.9558 0.9965 1.1025 1.2511 0.9887 1.0069 1.1566 1.0460 1.0803 1.4012 1.1013 1.0635 0.9740 0.9865 0.9134 1.1696 1.0859 1.0090 0.9522 0.9024 0.9086 0.8927 0.8825 0.8998 Lactate Lactic acid 1.0808 1.4115 0.5646 0.8722 0.9878 2.4694 1.2190 0.8438 0.7705 3.0703 2.0109 2.0109 7.9784 7.6355 2.7670 3.2710 5.9527 7.6029 1.9416 3.1248 3.1248 1.3532 2.6963 8.0135 3.9994 2.1727 2.9706 1.8680 1.2124 1.9148 1.8680 1.5894 1.9521 2.0538 1.9871 2.0049 3.3696 3.0070 2.9522 8.8733 8.0567 7.9250 7.1544 8.9394 8.5861 2.1511 2.3653 2.7839 8.5465 7.5126 8.6543 2.0016 2.2225 2.1181 2.2333 2.7129 2.7312 2.1826 2.5898 2.5746 2.3545 2.5638 2.5280 2.7829 2.7877 2.1250 2.9899 2.6772 2.6904 2.6276 2.5431 2.5836 2.5243 2.7956 2.3645 2.4170 2.3615 2.3972 2.7851 2.5322 2.5231 Leucine Leucine 0.5442 0.7484 0.5994 0.7236 0.4158 0.5395 0.6104 0.4232 0.5704 0.6034 0.8341 0.8341 1.3428 0.3934 0.7513 0.5732 0.4263 0.6100 0.6750 0.4878 0.4878 0.5205 0.4741 0.7737 0.8570 0.5260 0.5505 0.7590 0.8480 0.7598 0.6590 0.4768 0.6060 0.6238 0.8003 0.4113 0.9844 0.7446 0.7703 0.7940 0.8062 0.8278 1.0674 0.8447 0.8344 1.1515 0.9313 0.7852 0.8330 0.8872 0.8709 1.0270 0.9146 0.9758 0.3687 0.3932 0.4198 0.4397 0.3576 0.3774 0.4016 0.3579 0.3675 1.0905 0.9390 0.9729 1.0069 0.9573 0.9173 0.7020 0.8212 0.7747 1.0310 0.9631 0.8377 0.8844 0.8862 0.8615 0.8612 0.7661 0.7862 Lysine Lysine 0.2756 0.2816 0.3526 0.4621 0.4674 0.0684 0.3714 0.3952 0.4070 0.4001 0.7293 0.7293 0.6720 0.3685 0.5505 0.3632 0.4583 0.4095 0.7427 0.5665 0.5665 0.8082 0.8448 0.8015 0.5356 0.5878 0.4997 0.7290 0.7971 0.7290 0.6159 0.4786 0.6159 0.6230 0.7545 0.5108 0.8341 0.7722 0.7930 0.6205 0.6194 0.7659 1.0043 0.8823 0.8834 1.1971 0.9126 0.8786 0.7294 0.8855 0.7453 0.5293 0.5194 0.7171 1.1381 0.9835 1.0096 1.0871 0.8614 0.9065 0.9863 0.9443 0.9024 0.9318 0.8683 0.8498 0.9289 0.8285 0.9289 0.8617 0.8285 0.9289 0.9852 0.9289 0.8723 1.1198 0.9289 0.9392 0.9572 0.8450 0.8285 Methionine Methionine 0.5436 0.4100 0.5840 0.4136 0.5300 0.3825 0.0417 0.1374 0.0971 0.1885 0.2538 0.2538 0.3211 0.2044 0.2831 0.1713 0.1838 0.2483 0.1869 0.1341 0.1341 0.1384 0.1769 0.2996 0.2027 0.2169 0.1428 0.1829 0.2157 0.2050 0.1829 0.1713 0.2149 0.2751 0.2603 0.2513 0.2140 0.1884 0.1950 0.1996 0.1946 0.1880 0.2083 0.1841 0.1967 0.4340 0.3152 0.2347 0.2323 0.2228 0.2168 0.2143 0.2192 0.2398 0.3441 0.2367 0.3206 0.2148 0.2323 0.2416 0.2547 0.2299 0.2454 0.2623 0.2484 0.2787 0.2203 0.2577 0.2467 0.1845 0.2569 0.1388 0.3041 0.2662 0.2028 0.2448 0.2297 0.2147 0.2099 0.1975 0.2002 myo-Inositol Myo-inositol 0.2555 0.1754 0.1754 0.2397 0.3475 0.3475 0.1391 0.2517 0.1995 0.1961 0.1067 0.1067 0.3267 0.1952 0.1901 0.2651 0.2269 0.2301 0.2667 0.2261 0.2261 0.3290 0.2464 0.2291 0.2025 0.2672 0.2676 0.2832 0.1832 0.1863 0.0832 0.0932 0.0986 0.2039 0.1426 0.1616 0.2882 0.2248 0.2369 0.1343 0.1441 0.1461 0.1956 0.1555 0.1675 0.1624 0.1550 0.1669 0.1181 0.1122 0.1350 0.1705 0.1222 0.1204 0.3553 0.3130 0.3372 0.3398 0.3229 0.3789 0.2129 0.2403 0.2265 0.3549 0.2513 0.2997 0.3191 0.2510 0.2776 0.2595 0.2919 0.2833 0.2848 0.2617 0.2615 0.2655 0.2930 0.3001 0.3890 0.3632 0.3734 Nicotinurate Nicotinuric acid 0.0198 0.0351 0.0140 0.0168 0.0197 0.0492 0.0041 0.0180 0.0101 0.0201 0.0451 0.0451 0.0374 0.0182 0.0113 0.0400 0.0391 0.0329 0.0302 0.0234 0.0234 0.0171 0.0176 0.0554 0.0206 0.0150 0.0233 0.0870 0.0684 0.0456 0.0387 0.0317 0.0455 0.0853 0.0560 0.0448 0.0544 0.0377 0.0418 0.0474 0.0454 0.0487 0.0752 0.0518 0.0529 0.0589 0.0491 0.0414 0.0467 0.0376 0.0428 0.0541 0.0486 0.0441 0.0475 0.0403 0.0495 0.0596 0.0452 0.0533 0.0540 0.0395 0.0424 0.0562 0.0475 0.0498 0.0540 0.0440 0.0466 0.0475 0.0468 0.0384 0.0501 0.0414 0.0344 0.0555 0.0371 0.0427 0.0403 0.0382 0.0384 Phenylalanine Phenylalanine 0.2808 0.3841 0.3841 0.4857 0.6506 0.6506 0.4539 0.5261 0.4819 0.2954 0.4905 0.4905 0.6034 0.3681 0.4227 0.3742 0.2755 0.5692 0.3937 0.2769 0.2769 0.3621 0.2629 0.5774 0.3399 0.2777 0.2981 0.4201 0.5637 0.4788 0.3201 0.3383 0.4424 0.4854 0.4498 0.4312 0.4068 0.4186 0.4263 0.3997 0.3923 0.4164 0.4780 0.4213 0.4414 0.6785 0.4985 0.4521 0.3654 0.4026 0.4121 0.5481 0.5046 0.4954 0.5750 0.4456 0.4604 0.4834 0.4297 0.4490 0.5014 0.4218 0.4510 0.5234 0.4264 0.4623 0.5332 0.4284 0.4585 0.4080 0.4103 0.3637 0.4372 0.4195 0.4004 0.3509 0.3461 0.3866 0.4798 0.4231 0.4304 Pyroglutamate Pyroglutamic acid 1.2412 1.7002 1.2801 1.1522 1.7972 1.4930 4.5371 1.2896 3.4203 1.6934 1.6750 1.6750 2.1291 2.5157 1.7526 2.4603 2.3934 2.8800 2.6523 2.5630 2.5630 2.5966 2.6158 2.9671 2.1595 1.5853 0.6595 1.6488 1.9420 1.6880 1.6488 1.4372 1.8053 2.0523 1.9761 1.2453 2.0922 1.8853 1.8486 2.0491 1.9181 2.0438 2.2096 2.0243 2.2441 2.1994 2.1066 1.8480 2.4408 2.2705 2.4057 2.2355 1.9913 2.2550 2.6319 2.2270 2.2818 1.7431 2.0831 2.2256 2.1807 2.0034 2.0624 1.8802 1.9335 1.4567 2.5649 2.5044 2.2940 1.3842 1.7636 1.5560 2.5741 2.1125 1.8372 2.3583 1.9840 1.9818 1.9301 1.7173 1.7609 Pyruvate Pyruvic acid 0.8063 1.9083 0.7633 0.2777 0.2948 0.7370 0.3217 0.2599 0.2237 1.1680 0.1004 1.1004 0.6667 0.4890 0.2929 0.3130 0.3096 0.5456 1.7889 1.0886 1.0886 0.1177 0.6560 0.6338 0.3816 0.6207 1.4942 0.0916 0.0630 0.0723 0.1916 0.2879 0.2987 0.5962 0.2667 0.7118 0.1764 0.1490 0.1259 0.7336 0.5307 0.6009 0.5205 0.5896 0.6442 0.1462 0.0734 0.1376 0.5995 0.4764 0.6122 0.5918 0.6700 0.4535 0.0741 0.0675 0.0636 0.0549 0.0683 0.0634 0.0916 0.0704 0.0630 0.1514 0.1086 0.1774 0.1952 0.1153 0.1487 0.1292 0.1426 0.1093 0.1688 0.1903 0.1148 0.1344 0.1479 0.1179 0.1266 0.1587 0.1136 Serine Serine 0.1279 0.4114 0.1658 0.1196 0.3609 0.1902 0.1085 0.2565 0.1922 0.4553 0.5999 0.5999 0.5613 0.2416 0.3847 0.5300 0.3231 0.7715 0.6712 0.3898 0.3898 0.5400 0.6034 0.4999 0.5441 0.4107 0.6175 0.1938 0.1781 0.2417 0.0938 0.0611 0.0561 0.1092 0.0757 0.0926 0.4845 0.4547 0.4731 0.1896 0.1518 0.1420 0.3401 0.1112 0.2028 0.4298 0.4737 0.4399 0.1088 0.1122 0.1047 0.7766 0.6353 0.5436 0.6155 0.6276 0.6886 0.5900 0.5709 0.6238 0.6031 0.5441 0.5869 0.5831 0.5192 0.5917 0.9426 1.0786 0.8635 0.2162 0.2954 0.2836 0.3506 0.3194 0.2872 0.4967 0.4854 0.4352 0.6807 0.7179 0.7115 Threonine Threonine 0.2988 0.4690 0.2276 0.5648 0.5364 0.6411 0.3680 0.3486 0.3574 0.5346 0.7890 0.7890 0.9042 0.5842 0.7145 0.3551 0.3779 0.3554 0.6714 0.4361 0.4361 0.4414 0.5147 0.4710 0.7637 0.5175 0.5731 0.3870 0.1636 0.6177 0.1870 0.1586 0.1727 0.5406 0.2899 0.4434 0.9038 0.8836 0.8580 0.1258 0.1116 0.1144 0.2577 0.1269 0.2142 1.4963 1.4364 1.0282 0.1092 0.1141 0.1060 0.2694 0.2729 0.1009 1.0428 0.9963 0.9883 0.9152 0.8382 0.8521 1.0037 0.9471 0.9526 1.0422 0.8884 0.9199 0.6130 0.5880 0.8347 0.7136 0.9010 0.8083 1.0548 1.0213 0.9626 1.0920 0.8127 0.8109 0.9208 0.7624 0.7054 Tryptophan Tryptophan 0.0432 0.0570 0.0570 0.0378 0.0839 0.0839 0.0291 0.0509 0.0334 0.0424 0.0550 0.0550 0.0865 0.0321 0.0663 0.0228 0.0261 0.0552 0.0531 0.0460 0.0460 0.0125 0.0285 0.0641 0.0414 0.0307 0.0413 0.1100 0.0710 0.0582 0.1100 0.0639 0.0595 0.0773 0.0597 0.0450 0.0541 0.0397 0.0421 0.0588 0.0414 0.0425 0.0520 0.0357 0.0401 0.0781 0.0532 0.0413 0.0410 0.0338 0.0384 0.0558 0.0432 0.0427 0.0682 0.0528 0.0507 0.0497 0.0517 0.0528 0.0749 0.0728 0.0709 0.0603 0.0542 0.0518 0.0737 0.0607 0.0653 0.0473 0.0687 0.0440 0.0588 0.0616 0.0455 0.0791 0.0555 0.0521 0.0562 0.0439 0.0419 Tyrosine Tyrosine 0.1967 0.2713 0.1485 0.2640 0.2222 0.2554 0.1544 0.1832 0.1353 0.4303 0.4581 0.4581 0.5398 0.5189 0.5796 0.5690 0.5438 0.5056 0.3491 0.3238 0.4238 0.6060 0.4748 0.4380 0.4344 0.4992 0.2655 0.3696 0.4326 0.3015 0.2696 0.1436 0.3054 0.4521 0.3563 0.2653 0.5924 0.3732 0.3797 0.3634 0.3199 0.3778 0.4457 0.3668 0.3999 0.7270 0.5051 0.3773 0.4192 0.4232 0.4358 0.6650 0.5090 0.4172 0.4584 0.4131 0.4293 0.4656 0.3862 0.4016 0.4319 0.3591 0.3907 0.4555 0.4086 0.4157 0.5076 0.4398 0.4125 0.3610 0.4214 0.3645 0.4064 0.4229 0.3347 0.4719 0.3514 0.3820 0.3436 0.4017 0.3994 Valine Valine 1.5419 1.3922 1.2922 1.3985 1.3307 1.3307 1.3244 1.1824 1.2024 0.5619 0.8699 0.8699 0.8051 0.4521 0.6218 0.4316 0.3198 0.7380 0.7118 0.5201 0.5201 0.5265 0.5184 0.6215 0.6893 0.5225 0.6256 1.1299 1.1955 1.0521 0.6299 0.5066 0.7839 1.1221 1.0179 0.7777 1.1718 0.9165 0.9292 0.7905 0.7959 0.8049 0.8140 0.7499 0.7663 1.2222 0.9327 0.8197 0.7942 0.8099 0.7858 1.3196 0.9828 1.0497 1.2447 0.9665 1.0233 0.8649 0.9018 0.9394 1.0368 0.9234 0.9423 1.0772 0.9817 1.0622 1.0238 0.9829 1.0263 0.7845 0.9856 0.8706 1.0116 0.8992 0.8554 0.8977 0.8813 0.8346 0.8625 0.8099 0.8554