Metabolite_name	RefMet_name	CD_A549_3_1_IPI3_rep1	CD_A549_3_1_IPI3_rep2	CD_A549_3_1_IPI3_rep3	CD_A549_3_1_NIV3_rep1	CD_A549_3_1_NIV3_rep3	CD_A549_TW_NIV2_rep2	CD_A549_3_1_CTL3_rep1	CD_A549_3_1_CTL3_rep3	CD_A549_TW_CTL2_rep2	CD_A549_TW_IPI3_rep1	CD_A549_TW_IPI3_rep2	CD_A549_TW_IPI3_rep3	CD_A549_NIV2_rep2	CD_A549_TW_NIV3_rep1	CD_A549_TW_NIV3_rep3	CD_A549_CTL2_rep2	CD_A549_TW_CTL3_rep1	CD_A549_TW_CTL3_rep3	CD_A549_IPI3_rep1	CD_A549_IPI3_rep2	CD_A549_IPI3_rep3	CD_A549_3_1_NIV2_rep2	CD_A549_NIV3_rep1	CD_A549_NIV3_rep3	CD_A549_3_1_CTL2_rep2	CD_A549_CTL3_rep1	CD_A549_CTL3_rep3	CD_H292_TW_IPI1_rep1	CD_H292_TW_IPI1_rep2	CD_H292_TW_IPI1_rep3	CD_H292_TW_NIV1_rep1	CD_H292_TW_NIV1_rep2	CD_H292_TW_NIV1_rep3	CD_H292_TW_CTL1_rep1	CD_H292_TW_CTL1_rep2	CD_H292_TW_CTL1_rep3	CD_H292_IPI1_rep1	CD_H292_IPI1_rep2	CD_H292_IPI1_rep3	CD_H292_NIV1_rep1	CD_H292_NIV1_rep2	CD_H292_NIV1_rep3	CD_H292_CTL1_rep1	CD_H292_CTL1_rep2	CD_H292_CTL1_rep3	CD_H292_3_1_IPI1_rep1	CD_H292_3_1_IPI1_rep2	CD_H292_3_1_IPI1_rep3	CD_H292_3_1_NIV1_rep1	CD_H292_3_1_NIV1_rep2	CD_H292_3_1_NIV1_rep3	CD_H292_3_1_CTL1_rep1	CD_H292_3_1_CTL1_rep2	CD_H292_3_1_CTL1_rep3	CD_PC9_3_1_IPI1_rep1	CD_PC9_3_1_IPI1_rep2	CD_PC9_3_1_IPI1_rep3	CD_PC9_NIV1_rep1	CD_PC9_NIV1_rep2	CD_PC9_NIV1_rep3	CD_PC9_CTL1_rep1	CD_PC9_CTL1_rep2	CD_PC9_CTL1_rep3	CD_PC9_TW_IPI1_rep1	CD_PC9_TW_IPI1_rep2	CD_PC9_TW_IPI1_rep3	CD_PC9_TW_NIV1_rep1	CD_PC9_TW_NIV1_rep2	CD_PC9_TW_NIV1_rep3	CD_PC9_TW_CTL1_rep1	CD_PC9_TW_CTL3_rep	CD_PC9_TW_CTL3_rep3	CD_PC9_IPI3_rep1	CD_PC9_IPI3_rep2	CD_PC9_IPI3_rep3	CD_PC9_3_1_NIV1_rep1	CD_PC9_3_1_NIV1_rep2	CD_PC9_3_1_NIV1_rep3	CD_PC9_3_1_CTL1_rep1	CD_PC9_3_1_CTL1_rep2	CD_PC9_3_1_CTL1_rep3
Factors	-	Sample source:Non-small cell lung cancer cells | Cell line:A549 | Culture Type:Direct Co-culture | Immune checkpoint inhibitor:Ipilimumab	Sample source:Non-small cell lung cancer cells | Cell line:A549 | Culture Type:Direct Co-culture | Immune checkpoint inhibitor:Ipilimumab	Sample source:Non-small cell lung cancer cells | Cell line:A549 | Culture Type:Direct Co-culture | Immune checkpoint inhibitor:Ipilimumab	Sample source:Non-small cell lung cancer cells | Cell line:A549 | Culture Type:Direct Co-culture | Immune checkpoint inhibitor:Nivolumab	Sample source:Non-small cell lung cancer cells | Cell line:A549 | Culture Type:Direct Co-culture | Immune checkpoint inhibitor:Nivolumab	Sample source:Non-small cell lung cancer cells | Cell line:A549 | Culture Type:Direct Co-culture | Immune checkpoint inhibitor:Nivolumab	Sample source:Non-small cell lung cancer cells | Cell line:A549 | Culture Type:Direct Co-culture | Immune checkpoint inhibitor:No treatment	Sample source:Non-small cell lung cancer cells | Cell line:A549 | Culture Type:Direct Co-culture | Immune checkpoint inhibitor:No treatment	Sample source:Non-small cell lung cancer cells | Cell line:A549 | Culture Type:Direct Co-culture | Immune checkpoint inhibitor:No treatment	Sample source:Non-small cell lung cancer cells | Cell line:A549 | Culture Type:Indirect Co-culture | Immune checkpoint inhibitor:Ipilimumab	Sample source:Non-small cell lung cancer cells | Cell line:A549 | Culture Type:Indirect Co-culture | Immune checkpoint inhibitor:Ipilimumab	Sample source:Non-small cell lung cancer cells | Cell line:A549 | Culture Type:Indirect Co-culture | Immune checkpoint inhibitor:Ipilimumab	Sample source:Non-small cell lung cancer cells | Cell line:A549 | Culture Type:Indirect Co-culture | Immune checkpoint inhibitor:Nivolumab	Sample source:Non-small cell lung cancer cells | Cell line:A549 | Culture Type:Indirect Co-culture | Immune checkpoint inhibitor:Nivolumab	Sample source:Non-small cell lung cancer cells | Cell line:A549 | Culture Type:Indirect Co-culture | Immune checkpoint inhibitor:Nivolumab	Sample source:Non-small cell lung cancer cells | Cell line:A549 | Culture Type:Indirect Co-culture | Immune checkpoint inhibitor:No treatment	Sample source:Non-small cell lung cancer cells | Cell line:A549 | Culture Type:Indirect Co-culture | Immune checkpoint inhibitor:No treatment	Sample source:Non-small cell lung cancer cells | Cell line:A549 | Culture Type:Indirect Co-culture | Immune checkpoint inhibitor:No treatment	Sample source:Non-small cell lung cancer cells | Cell line:A549 | Culture Type:Monoculture | Immune checkpoint inhibitor:Ipilimumab	Sample source:Non-small cell lung cancer cells | Cell line:A549 | Culture Type:Monoculture | Immune checkpoint inhibitor:Ipilimumab	Sample source:Non-small cell lung cancer cells | Cell line:A549 | Culture Type:Monoculture | Immune checkpoint inhibitor:Ipilimumab	Sample source:Non-small cell lung cancer cells | Cell line:A549 | Culture Type:Monoculture | Immune checkpoint inhibitor:Nivolumab	Sample source:Non-small cell lung cancer cells | Cell line:A549 | Culture Type:Monoculture | Immune checkpoint inhibitor:Nivolumab	Sample source:Non-small cell lung cancer cells | Cell line:A549 | Culture Type:Monoculture | Immune checkpoint inhibitor:Nivolumab	Sample source:Non-small cell lung cancer cells | Cell line:A549 | Culture Type:Monoculture | Immune checkpoint inhibitor:No treatment	Sample source:Non-small cell lung cancer cells | Cell line:A549 | Culture Type:Monoculture | Immune checkpoint inhibitor:No treatment	Sample source:Non-small cell lung cancer cells | Cell line:A549 | Culture Type:Monoculture | Immune checkpoint inhibitor:No treatment	Sample source:Non-small cell lung cancer cells | Cell line:H292 | Culture Type:Direct Co-culture | Immune checkpoint inhibitor:Ipilimumab	Sample source:Non-small cell lung cancer cells | Cell line:H292 | Culture Type:Direct Co-culture | Immune checkpoint inhibitor:Ipilimumab	Sample source:Non-small cell lung cancer cells | Cell line:H292 | Culture Type:Direct Co-culture | Immune checkpoint inhibitor:Ipilimumab	Sample source:Non-small cell lung cancer cells | Cell line:H292 | Culture Type:Direct Co-culture | Immune checkpoint inhibitor:Nivolumab	Sample source:Non-small cell lung cancer cells | Cell line:H292 | Culture Type:Direct Co-culture | Immune checkpoint inhibitor:Nivolumab	Sample source:Non-small cell lung cancer cells | Cell line:H292 | Culture Type:Direct Co-culture | Immune checkpoint inhibitor:Nivolumab	Sample source:Non-small cell lung cancer cells | Cell line:H292 | Culture Type:Direct Co-culture | Immune checkpoint inhibitor:No treatment	Sample source:Non-small cell lung cancer cells | Cell line:H292 | Culture Type:Direct Co-culture | Immune checkpoint inhibitor:No treatment	Sample source:Non-small cell lung cancer cells | Cell line:H292 | Culture Type:Direct Co-culture | Immune checkpoint inhibitor:No treatment	Sample source:Non-small cell lung cancer cells | Cell line:H292 | Culture Type:Indirect Co-culture | Immune checkpoint inhibitor:Ipilimumab	Sample source:Non-small cell lung cancer cells | Cell line:H292 | Culture Type:Indirect Co-culture | Immune checkpoint inhibitor:Ipilimumab	Sample source:Non-small cell lung cancer cells | Cell line:H292 | Culture Type:Indirect Co-culture | Immune checkpoint inhibitor:Ipilimumab	Sample source:Non-small cell lung cancer cells | Cell line:H292 | Culture Type:Indirect Co-culture | Immune checkpoint inhibitor:Nivolumab	Sample source:Non-small cell lung cancer cells | Cell line:H292 | Culture Type:Indirect Co-culture | Immune checkpoint inhibitor:Nivolumab	Sample source:Non-small cell lung cancer cells | Cell line:H292 | Culture Type:Indirect Co-culture | Immune checkpoint inhibitor:Nivolumab	Sample source:Non-small cell lung cancer cells | Cell line:H292 | Culture Type:Indirect Co-culture | Immune checkpoint inhibitor:No treatment	Sample source:Non-small cell lung cancer cells | Cell line:H292 | Culture Type:Indirect Co-culture | Immune checkpoint inhibitor:No treatment	Sample source:Non-small cell lung cancer cells | Cell line:H292 | Culture Type:Indirect Co-culture | Immune checkpoint inhibitor:No treatment	Sample source:Non-small cell lung cancer cells | Cell line:H292 | Culture Type:Monoculture | Immune checkpoint inhibitor:Ipilimumab	Sample source:Non-small cell lung cancer cells | Cell line:H292 | Culture Type:Monoculture | Immune checkpoint inhibitor:Ipilimumab	Sample source:Non-small cell lung cancer cells | Cell line:H292 | Culture Type:Monoculture | Immune checkpoint inhibitor:Ipilimumab	Sample source:Non-small cell lung cancer cells | Cell line:H292 | Culture Type:Monoculture | Immune checkpoint inhibitor:Nivolumab	Sample source:Non-small cell lung cancer cells | Cell line:H292 | Culture Type:Monoculture | Immune checkpoint inhibitor:Nivolumab	Sample source:Non-small cell lung cancer cells | Cell line:H292 | Culture Type:Monoculture | Immune checkpoint inhibitor:Nivolumab	Sample source:Non-small cell lung cancer cells | Cell line:H292 | Culture Type:Monoculture | Immune checkpoint inhibitor:No treatment	Sample source:Non-small cell lung cancer cells | Cell line:H292 | Culture Type:Monoculture | Immune checkpoint inhibitor:No treatment	Sample source:Non-small cell lung cancer cells | Cell line:H292 | Culture Type:Monoculture | Immune checkpoint inhibitor:No treatment	Sample source:Non-small cell lung cancer cells | Cell line:PC-9 | Culture Type:Direct Co-culture | Immune checkpoint inhibitor:Ipilimumab	Sample source:Non-small cell lung cancer cells | Cell line:PC-9 | Culture Type:Direct Co-culture | Immune checkpoint inhibitor:Ipilimumab	Sample source:Non-small cell lung cancer cells | Cell line:PC-9 | Culture Type:Direct Co-culture | Immune checkpoint inhibitor:Ipilimumab	Sample source:Non-small cell lung cancer cells | Cell line:PC-9 | Culture Type:Direct Co-culture | Immune checkpoint inhibitor:Nivolumab	Sample source:Non-small cell lung cancer cells | Cell line:PC-9 | Culture Type:Direct Co-culture | Immune checkpoint inhibitor:Nivolumab	Sample source:Non-small cell lung cancer cells | Cell line:PC-9 | Culture Type:Direct Co-culture | Immune checkpoint inhibitor:Nivolumab	Sample source:Non-small cell lung cancer cells | Cell line:PC-9 | Culture Type:Direct Co-culture | Immune checkpoint inhibitor:No treatment	Sample source:Non-small cell lung cancer cells | Cell line:PC-9 | Culture Type:Direct Co-culture | Immune checkpoint inhibitor:No treatment	Sample source:Non-small cell lung cancer cells | Cell line:PC-9 | Culture Type:Direct Co-culture | Immune checkpoint inhibitor:No treatment	Sample source:Non-small cell lung cancer cells | Cell line:PC-9 | Culture Type:Indirect Co-culture | Immune checkpoint inhibitor:Ipilimumab	Sample source:Non-small cell lung cancer cells | Cell line:PC-9 | Culture Type:Indirect Co-culture | Immune checkpoint inhibitor:Ipilimumab	Sample source:Non-small cell lung cancer cells | Cell line:PC-9 | Culture Type:Indirect Co-culture | Immune checkpoint inhibitor:Ipilimumab	Sample source:Non-small cell lung cancer cells | Cell line:PC-9 | Culture Type:Indirect Co-culture | Immune checkpoint inhibitor:Nivolumab	Sample source:Non-small cell lung cancer cells | Cell line:PC-9 | Culture Type:Indirect Co-culture | Immune checkpoint inhibitor:Nivolumab	Sample source:Non-small cell lung cancer cells | Cell line:PC-9 | Culture Type:Indirect Co-culture | Immune checkpoint inhibitor:Nivolumab	Sample source:Non-small cell lung cancer cells | Cell line:PC-9 | Culture Type:Indirect Co-culture | Immune checkpoint inhibitor:No treatment	Sample source:Non-small cell lung cancer cells | Cell line:PC-9 | Culture Type:Indirect Co-culture | Immune checkpoint inhibitor:No treatment	Sample source:Non-small cell lung cancer cells | Cell line:PC-9 | Culture Type:Indirect Co-culture | Immune checkpoint inhibitor:No treatment	Sample source:Non-small cell lung cancer cells | Cell line:PC-9 | Culture Type:Monoculture | Immune checkpoint inhibitor:Ipilimumab	Sample source:Non-small cell lung cancer cells | Cell line:PC-9 | Culture Type:Monoculture | Immune checkpoint inhibitor:Ipilimumab	Sample source:Non-small cell lung cancer cells | Cell line:PC-9 | Culture Type:Monoculture | Immune checkpoint inhibitor:Ipilimumab	Sample source:Non-small cell lung cancer cells | Cell line:PC-9 | Culture Type:Monoculture | Immune checkpoint inhibitor:Nivolumab	Sample source:Non-small cell lung cancer cells | Cell line:PC-9 | Culture Type:Monoculture | Immune checkpoint inhibitor:Nivolumab	Sample source:Non-small cell lung cancer cells | Cell line:PC-9 | Culture Type:Monoculture | Immune checkpoint inhibitor:Nivolumab	Sample source:Non-small cell lung cancer cells | Cell line:PC-9 | Culture Type:Monoculture | Immune checkpoint inhibitor:No treatment	Sample source:Non-small cell lung cancer cells | Cell line:PC-9 | Culture Type:Monoculture | Immune checkpoint inhibitor:No treatment	Sample source:Non-small cell lung cancer cells | Cell line:PC-9 | Culture Type:Monoculture | Immune checkpoint inhibitor:No treatment
Acetate	Acetic acid	0.2099	0.3110	0.2444	0.6084	0.4126	0.5314	0.5038	0.6180	0.3499	0.4671	0.4133	0.4133	1.7881	1.9696	1.0971	1.1826	1.3464	2.3384	0.7700	0.4694	0.8694	1.5238	1.5356	2.1084	1.4439	1.2335	1.3550	0.2587	0.1254	0.1152	0.4587	0.2525	0.3769	0.8641	1.3927	1.3043	0.3514	0.3182	0.2570	1.8406	1.1120	1.4837	1.2322	1.3207	1.4220	0.5988	0.5920	0.4813	1.8166	2.1626	1.9989	0.8013	0.6294	1.1696	0.0459	0.0467	0.0710	0.0506	0.0388	0.0470	0.0968	0.0518	0.0476	0.2186	0.2378	0.1981	0.1863	0.2172	0.2366	0.1594	0.1898	0.1623	0.1928	0.2755	0.1545	0.2212	0.2424	0.2267	0.2873	0.2657	0.2267
Alanine	Alanine	0.1583	0.1946	0.1578	0.1765	0.1414	0.1535	0.1433	0.1206	0.1887	0.3687	0.2291	0.2910	0.3640	0.2615	0.3440	0.2285	0.2768	0.3579	0.3934	0.3740	0.3740	0.3850	0.2713	0.3466	0.2761	0.3284	0.3788	0.3086	0.2746	0.2628	0.1086	0.0655	0.1018	0.3887	0.2194	0.3670	0.2639	0.2178	0.2439	0.3632	0.3400	0.3249	0.2559	0.2059	0.2182	0.2636	0.1634	0.1928	0.3694	0.3741	0.3916	0.3032	0.2146	0.2024	0.1475	0.1243	0.1515	0.1214	0.1315	0.1339	0.1432	0.1251	0.1383	0.4010	0.3171	0.3951	0.3880	0.3493	0.3076	0.3120	0.3019	0.2967	0.3069	0.3243	0.2561	0.2988	0.2546	0.2785	0.4009	0.3488	0.3335
Arginine	Arginine	0.2534	0.6611	0.2644	0.2275	0.2753	2.1883	0.1983	0.2127	0.6607	0.5632	0.5364	0.5364	0.8599	0.7590	0.5243	0.5859	0.5134	0.7283	0.7557	0.6928	0.6928	0.4040	0.7242	1.2303	0.4366	0.4807	0.4886	0.2494	0.1414	0.1499	0.2494	0.1101	0.1150	0.2947	0.2306	0.2119	0.7045	0.6699	0.6567	0.5368	0.5243	0.5572	0.6956	0.6222	0.6477	0.6507	0.5961	0.5660	0.6129	0.6702	0.6317	0.3777	0.3654	0.3521	0.4998	0.4367	0.4575	0.4077	0.4070	0.4229	0.4099	0.4012	0.4256	0.4429	0.4494	0.4949	0.4898	0.4847	0.4958	0.4008	0.4167	0.4050	0.5039	0.5114	0.5177	0.3750	0.3815	0.4045	0.3957	0.2933	0.3014
Aspartate	Aspartic acid	0.1064	0.1754	0.1102	0.1012	0.0995	0.1488	0.0846	0.0742	0.0616	0.2278	0.2507	0.2507	0.1443	0.0916	0.0777	0.1557	0.1879	0.2375	0.2028	0.1511	0.1511	0.1920	0.1366	0.1728	0.2369	0.1041	0.1673	0.0306	0.0304	0.0286	0.0106	0.0176	0.0192	0.0339	0.0290	0.0286	0.0597	0.0365	0.0405	0.0530	0.0599	0.0592	0.0703	0.0665	0.0857	0.1068	0.0906	0.0808	0.0655	0.0544	0.0627	0.0654	0.0586	0.0649	0.0410	0.0351	0.0361	0.0402	0.0331	0.0311	0.0270	0.0215	0.0227	0.0610	0.0325	0.0611	0.0321	0.0389	0.0300	0.0343	0.0378	0.0262	0.0355	0.0301	0.0292	0.0383	0.0385	0.0411	0.0271	0.0297	0.0265
Choline	Choline	0.1374	0.2403	0.2403	0.2663	0.2365	0.2365	0.1724	0.2089	0.1780	0.1585	0.1143	0.4300	0.4085	0.1182	0.2725	0.1485	0.2126	0.1423	0.2583	0.1603	0.1603	0.1834	0.1803	0.1981	0.1633	0.0974	0.1704	0.0233	0.0277	0.0269	0.0333	0.0115	0.0307	0.0309	0.0344	0.0262	0.0906	0.0508	0.0595	0.0260	0.0357	0.0439	0.0419	0.0334	0.0388	0.0595	0.0645	0.0544	0.0227	0.0340	0.0281	0.0680	0.0604	0.0486	0.0663	0.0554	0.0641	0.0791	0.0611	0.0667	0.0730	0.0863	0.0755	0.1439	0.0647	0.1318	0.0714	0.0668	0.0705	0.0513	0.0664	0.0604	0.0582	0.0693	0.0476	0.0626	0.0585	0.0602	0.0657	0.0626	0.0609
Cystine	Cystine	0.1724	0.2071	0.1828	0.1682	0.1458	0.2645	0.1956	0.1793	0.1591	0.1428	0.3547	0.1547	0.1302	0.1533	0.1662	0.1718	0.1291	0.1927	0.2215	0.2432	0.2432	0.1469	0.1633	0.1501	0.1387	0.1509	0.1943	0.1201	0.1067	0.0964	0.0701	0.0689	0.0748	0.2442	0.1832	0.1650	0.2409	0.1717	0.1932	0.1005	0.1186	0.1113	0.2065	0.2228	0.1962	0.2513	0.2329	0.1809	0.1025	0.1132	0.1020	0.1416	0.1409	0.1351	0.1170	0.0990	0.1131	0.1284	0.1321	0.1116	0.1081	0.0605	0.1405	0.1479	0.1300	0.1115	0.1424	0.1302	0.1734	0.0952	0.0996	0.0954	0.1106	0.1002	0.0981	0.0954	0.0939	0.0886	0.1312	0.1231	0.1211
Formate	Formic acid	0.0337	0.0311	0.0311	0.0491	0.0698	0.0698	0.0358	0.0635	0.0174	0.0409	0.0884	0.0884	0.0750	0.9740	0.0391	0.0388	0.0548	0.0708	0.0364	0.0352	0.0352	0.0142	0.0301	0.0905	0.0431	0.0328	0.0860	0.6395	0.0779	0.0607	0.0395	0.0381	0.0819	0.1391	0.1401	0.1929	0.0591	0.0731	0.0540	0.1849	0.1868	0.1847	0.2205	0.1682	0.2129	0.1029	0.1421	0.0863	0.1760	0.2155	0.2387	0.2076	0.1415	0.2235	0.0549	0.0454	0.0488	0.0385	0.0353	0.0402	0.0498	0.0434	0.0461	0.0425	0.0443	0.0405	0.0584	0.0551	0.0448	0.0348	0.0469	0.0433	0.0496	0.0437	0.0385	0.0378	0.0358	0.0442	0.0464	0.0425	0.0446
Fumarate	Fumaric acid																												0.0052	0.0031	0.0034	0.0052	0.0031	0.0034	0.0087	0.0098	0.0070	0.0061	0.0064	0.0056	0.0034	0.0053	0.0048	0.0030	0.0035	0.0031	0.0009	0.0002	0.0035	0.0036	0.0055	0.0034	0.0019	0.0018	0.0026	0.0077	0.0057	0.0075	0.0059	0.0068	0.0077	0.0068	0.0057	0.0072	0.0035	0.0050	0.0044	0.0045	0.0046	0.0059	0.0060	0.0066	0.0041	0.0059	0.0061	0.0067	0.0058	0.0063	0.0059	0.0050	0.0048	0.0052
Glucose	Glucose	18.3623	23.4488	23.4488	12.8466	18.4319	18.4319	20.0690	21.2185	22.5498	19.0104	17.5671	17.5671	19.1707	11.8337	11.0591	19.6902	19.0821	19.0254	14.4246	18.2226	18.2226	14.3495	14.0364	14.9583	15.9010	15.1387	18.8249	22.9014	23.6338	24.9567	21.9014	19.1659	23.2583	22.9634	23.6772	23.8429	23.0666	23.4005	24.5027	22.5466	22.7749	22.2399	22.3231	23.5251	25.3261	21.6675	22.7994	22.7959	22.7441	24.7188	24.0764	22.4173	23.8724	23.1070	24.2620	24.4015	24.4777	24.8999	24.2927	24.4845	24.6501	24.4914	24.3826	24.6877	24.6194	24.6046	25.1198	24.0046	23.8875	25.8079	24.1518	23.9512	25.9445	23.7473	21.1693	24.1861	24.2531	24.2819	25.4447	24.4587	24.4259
Glutamate	Glutamic acid	0.0987	0.0926	0.1170	0.0819	0.1410	0.1353	0.1092	0.0975	0.1415	0.3054	0.2750	0.2750	0.3018	0.3626	0.3854	0.2994	0.3236	0.3283	0.2682	0.2523	0.2523	0.2016	0.2534	0.2943	0.1460	0.1439	0.1145	0.2393	0.1708	0.1558	0.2393	0.1224	0.1492	0.3423	0.3484	0.3511	0.2439	0.2214	0.2104	0.3104	0.3172	0.3274	0.4171	0.4316	0.4106	0.3157	0.2559	0.2145	0.3327	0.2901	0.2928	0.2520	0.1450	0.1916	0.2333	0.1556	0.1601	0.2354	0.1618	0.1813	0.2047	0.2070	0.1949	0.2291	0.1930	0.2167	0.2416	0.2542	0.2180	0.1633	0.1922	0.1746	0.1338	0.1471	0.1305	0.1459	0.1312	0.1640	0.2477	0.1804	0.1656
Glutamine	Glutamine	0.6642	0.8429	0.7372	0.4662	0.4361	0.4402	0.2861	0.2906	0.3456	1.5023	1.2275	1.2275	0.3734	0.3299	0.3814	0.5047	0.4995	0.5954	1.8508	1.4276	1.4276	0.1488	1.0946	0.9664	1.5058	1.3381	1.4980	2.0053	1.8872	1.8793	2.0053	1.9122	1.8630	1.5594	1.5115	1.0114	1.6725	1.6814	1.8848	1.2748	1.2648	1.4059	1.6834	1.5864	1.8080	1.9633	1.9587	1.7079	1.3849	1.4978	1.4625	1.8103	1.8936	1.8241	1.6690	1.7209	1.6989	1.7009	1.6575	1.6334	1.5268	1.6097	1.6434	1.7294	1.6357	1.6885	1.8825	1.6685	1.7186	1.4120	1.5451	1.4694	1.4827	1.4590	1.4097	1.6754	1.6929	1.6558	1.7914	1.7277	1.7437
Glycine	Glycine	0.2880	0.2706	0.2802	0.3095	0.3196	0.3990	0.2902	0.2695	0.2028	0.6107	0.8538	0.7538	0.6497	0.6760	0.5391	0.5217	0.6463	0.6850	0.5161	0.4799	0.4799	0.4961	0.4826	0.5768	0.5801	0.4899	0.5242	0.2380	0.2306	0.2485	0.1380	0.1660	0.0509	0.3788	0.3857	0.4882	0.7281	0.7233	0.7481	0.1057	0.1167	0.1233	0.3169	0.2148	0.3169	0.6417	0.5229	0.7674	0.2511	0.3581	0.3466	0.3320	0.4401	0.4480	0.1805	0.1886	0.1987	0.2547	0.2481	0.2597	0.1866	0.2132	0.2514	0.3377	0.3141	0.3793	0.1988	0.1904	0.1738	0.2034	0.2508	0.2541	0.2619	0.2580	0.2644	0.5430	0.6430	0.6389	0.4305	0.6558	0.4357
Histidine	Histidine	0.1553	0.1469	0.1588	0.1460	0.1660	0.1150	0.1417	0.1418	0.1140	0.1340	0.0966	0.0966	0.1642	0.1302	0.1675	0.1150	0.0921	0.1475	0.1585	0.1423	0.1423	0.1256	0.1183	0.1741	0.1101	0.1454	0.1438	0.1512	0.2349	0.2117	0.1512	0.0877	0.1533	0.3789	0.2260	0.2268	0.3343	0.2041	0.2108	0.2003	0.2070	0.2211	0.3137	0.2187	0.2449	0.3755	0.2876	0.2251	0.2409	0.2645	0.2507	0.2927	0.3177	0.2629	0.3129	0.2539	0.2658	0.1802	0.2047	0.2361	0.2800	0.2439	0.2473	0.3128	0.2453	0.3226	0.3408	0.2605	0.2690	0.2605	0.2574	0.2217	0.3329	0.2738	0.2051	0.2294	0.2143	0.2264	0.2845	0.2345	0.2417
Isoleucine	Isoleucine	0.4756	0.4636	0.3054	0.6597	0.6383	0.5957	0.5216	0.4206	0.4402	0.6226	0.9244	0.9244	0.7884	0.4027	0.5099	0.8611	0.8135	0.9683	0.8509	0.6091	0.6091	0.7176	0.4992	0.9903	1.0131	0.6230	0.6704	0.9281	1.1365	0.8350	0.9281	0.4699	0.8879	0.8430	0.8677	0.5692	1.2595	0.9721	0.9832	0.7242	0.8213	0.8770	1.0131	0.9304	1.0308	1.4737	1.2572	1.0629	0.9258	0.9554	0.9889	1.1401	1.3781	1.1318	1.3719	1.0387	1.1089	0.9558	0.9965	1.1025	1.2511	0.9887	1.0069	1.1566	1.0460	1.0803	1.4012	1.1013	1.0635	0.9740	0.9865	0.9134	1.1696	1.0859	1.0090	0.9522	0.9024	0.9086	0.8927	0.8825	0.8998
Lactate	Lactic acid	1.0808	1.4115	0.5646	0.8722	0.9878	2.4694	1.2190	0.8438	0.7705	3.0703	2.0109	2.0109	7.9784	7.6355	2.7670	3.2710	5.9527	7.6029	1.9416	3.1248	3.1248	1.3532	2.6963	8.0135	3.9994	2.1727	2.9706	1.8680	1.2124	1.9148	1.8680	1.5894	1.9521	2.0538	1.9871	2.0049	3.3696	3.0070	2.9522	8.8733	8.0567	7.9250	7.1544	8.9394	8.5861	2.1511	2.3653	2.7839	8.5465	7.5126	8.6543	2.0016	2.2225	2.1181	2.2333	2.7129	2.7312	2.1826	2.5898	2.5746	2.3545	2.5638	2.5280	2.7829	2.7877	2.1250	2.9899	2.6772	2.6904	2.6276	2.5431	2.5836	2.5243	2.7956	2.3645	2.4170	2.3615	2.3972	2.7851	2.5322	2.5231
Leucine	Leucine	0.5442	0.7484	0.5994	0.7236	0.4158	0.5395	0.6104	0.4232	0.5704	0.6034	0.8341	0.8341	1.3428	0.3934	0.7513	0.5732	0.4263	0.6100	0.6750	0.4878	0.4878	0.5205	0.4741	0.7737	0.8570	0.5260	0.5505	0.7590	0.8480	0.7598	0.6590	0.4768	0.6060	0.6238	0.8003	0.4113	0.9844	0.7446	0.7703	0.7940	0.8062	0.8278	1.0674	0.8447	0.8344	1.1515	0.9313	0.7852	0.8330	0.8872	0.8709	1.0270	0.9146	0.9758	0.3687	0.3932	0.4198	0.4397	0.3576	0.3774	0.4016	0.3579	0.3675	1.0905	0.9390	0.9729	1.0069	0.9573	0.9173	0.7020	0.8212	0.7747	1.0310	0.9631	0.8377	0.8844	0.8862	0.8615	0.8612	0.7661	0.7862
Lysine	Lysine	0.2756	0.2816	0.3526	0.4621	0.4674	0.0684	0.3714	0.3952	0.4070	0.4001	0.7293	0.7293	0.6720	0.3685	0.5505	0.3632	0.4583	0.4095	0.7427	0.5665	0.5665	0.8082	0.8448	0.8015	0.5356	0.5878	0.4997	0.7290	0.7971	0.7290	0.6159	0.4786	0.6159	0.6230	0.7545	0.5108	0.8341	0.7722	0.7930	0.6205	0.6194	0.7659	1.0043	0.8823	0.8834	1.1971	0.9126	0.8786	0.7294	0.8855	0.7453	0.5293	0.5194	0.7171	1.1381	0.9835	1.0096	1.0871	0.8614	0.9065	0.9863	0.9443	0.9024	0.9318	0.8683	0.8498	0.9289	0.8285	0.9289	0.8617	0.8285	0.9289	0.9852	0.9289	0.8723	1.1198	0.9289	0.9392	0.9572	0.8450	0.8285
Methionine	Methionine	0.5436	0.4100	0.5840	0.4136	0.5300	0.3825	0.0417	0.1374	0.0971	0.1885	0.2538	0.2538	0.3211	0.2044	0.2831	0.1713	0.1838	0.2483	0.1869	0.1341	0.1341	0.1384	0.1769	0.2996	0.2027	0.2169	0.1428	0.1829	0.2157	0.2050	0.1829	0.1713	0.2149	0.2751	0.2603	0.2513	0.2140	0.1884	0.1950	0.1996	0.1946	0.1880	0.2083	0.1841	0.1967	0.4340	0.3152	0.2347	0.2323	0.2228	0.2168	0.2143	0.2192	0.2398	0.3441	0.2367	0.3206	0.2148	0.2323	0.2416	0.2547	0.2299	0.2454	0.2623	0.2484	0.2787	0.2203	0.2577	0.2467	0.1845	0.2569	0.1388	0.3041	0.2662	0.2028	0.2448	0.2297	0.2147	0.2099	0.1975	0.2002
myo-Inositol	Myo-inositol	0.2555	0.1754	0.1754	0.2397	0.3475	0.3475	0.1391	0.2517	0.1995	0.1961	0.1067	0.1067	0.3267	0.1952	0.1901	0.2651	0.2269	0.2301	0.2667	0.2261	0.2261	0.3290	0.2464	0.2291	0.2025	0.2672	0.2676	0.2832	0.1832	0.1863	0.0832	0.0932	0.0986	0.2039	0.1426	0.1616	0.2882	0.2248	0.2369	0.1343	0.1441	0.1461	0.1956	0.1555	0.1675	0.1624	0.1550	0.1669	0.1181	0.1122	0.1350	0.1705	0.1222	0.1204	0.3553	0.3130	0.3372	0.3398	0.3229	0.3789	0.2129	0.2403	0.2265	0.3549	0.2513	0.2997	0.3191	0.2510	0.2776	0.2595	0.2919	0.2833	0.2848	0.2617	0.2615	0.2655	0.2930	0.3001	0.3890	0.3632	0.3734
Nicotinurate	Nicotinuric acid	0.0198	0.0351	0.0140	0.0168	0.0197	0.0492	0.0041	0.0180	0.0101	0.0201	0.0451	0.0451	0.0374	0.0182	0.0113	0.0400	0.0391	0.0329	0.0302	0.0234	0.0234	0.0171	0.0176	0.0554	0.0206	0.0150	0.0233	0.0870	0.0684	0.0456	0.0387	0.0317	0.0455	0.0853	0.0560	0.0448	0.0544	0.0377	0.0418	0.0474	0.0454	0.0487	0.0752	0.0518	0.0529	0.0589	0.0491	0.0414	0.0467	0.0376	0.0428	0.0541	0.0486	0.0441	0.0475	0.0403	0.0495	0.0596	0.0452	0.0533	0.0540	0.0395	0.0424	0.0562	0.0475	0.0498	0.0540	0.0440	0.0466	0.0475	0.0468	0.0384	0.0501	0.0414	0.0344	0.0555	0.0371	0.0427	0.0403	0.0382	0.0384
Phenylalanine	Phenylalanine	0.2808	0.3841	0.3841	0.4857	0.6506	0.6506	0.4539	0.5261	0.4819	0.2954	0.4905	0.4905	0.6034	0.3681	0.4227	0.3742	0.2755	0.5692	0.3937	0.2769	0.2769	0.3621	0.2629	0.5774	0.3399	0.2777	0.2981	0.4201	0.5637	0.4788	0.3201	0.3383	0.4424	0.4854	0.4498	0.4312	0.4068	0.4186	0.4263	0.3997	0.3923	0.4164	0.4780	0.4213	0.4414	0.6785	0.4985	0.4521	0.3654	0.4026	0.4121	0.5481	0.5046	0.4954	0.5750	0.4456	0.4604	0.4834	0.4297	0.4490	0.5014	0.4218	0.4510	0.5234	0.4264	0.4623	0.5332	0.4284	0.4585	0.4080	0.4103	0.3637	0.4372	0.4195	0.4004	0.3509	0.3461	0.3866	0.4798	0.4231	0.4304
Pyroglutamate	Pyroglutamic acid	1.2412	1.7002	1.2801	1.1522	1.7972	1.4930	4.5371	1.2896	3.4203	1.6934	1.6750	1.6750	2.1291	2.5157	1.7526	2.4603	2.3934	2.8800	2.6523	2.5630	2.5630	2.5966	2.6158	2.9671	2.1595	1.5853	0.6595	1.6488	1.9420	1.6880	1.6488	1.4372	1.8053	2.0523	1.9761	1.2453	2.0922	1.8853	1.8486	2.0491	1.9181	2.0438	2.2096	2.0243	2.2441	2.1994	2.1066	1.8480	2.4408	2.2705	2.4057	2.2355	1.9913	2.2550	2.6319	2.2270	2.2818	1.7431	2.0831	2.2256	2.1807	2.0034	2.0624	1.8802	1.9335	1.4567	2.5649	2.5044	2.2940	1.3842	1.7636	1.5560	2.5741	2.1125	1.8372	2.3583	1.9840	1.9818	1.9301	1.7173	1.7609
Pyruvate	Pyruvic acid	0.8063	1.9083	0.7633	0.2777	0.2948	0.7370	0.3217	0.2599	0.2237	1.1680	0.1004	1.1004	0.6667	0.4890	0.2929	0.3130	0.3096	0.5456	1.7889	1.0886	1.0886	0.1177	0.6560	0.6338	0.3816	0.6207	1.4942	0.0916	0.0630	0.0723	0.1916	0.2879	0.2987	0.5962	0.2667	0.7118	0.1764	0.1490	0.1259	0.7336	0.5307	0.6009	0.5205	0.5896	0.6442	0.1462	0.0734	0.1376	0.5995	0.4764	0.6122	0.5918	0.6700	0.4535	0.0741	0.0675	0.0636	0.0549	0.0683	0.0634	0.0916	0.0704	0.0630	0.1514	0.1086	0.1774	0.1952	0.1153	0.1487	0.1292	0.1426	0.1093	0.1688	0.1903	0.1148	0.1344	0.1479	0.1179	0.1266	0.1587	0.1136
Serine	Serine	0.1279	0.4114	0.1658	0.1196	0.3609	0.1902	0.1085	0.2565	0.1922	0.4553	0.5999	0.5999	0.5613	0.2416	0.3847	0.5300	0.3231	0.7715	0.6712	0.3898	0.3898	0.5400	0.6034	0.4999	0.5441	0.4107	0.6175	0.1938	0.1781	0.2417	0.0938	0.0611	0.0561	0.1092	0.0757	0.0926	0.4845	0.4547	0.4731	0.1896	0.1518	0.1420	0.3401	0.1112	0.2028	0.4298	0.4737	0.4399	0.1088	0.1122	0.1047	0.7766	0.6353	0.5436	0.6155	0.6276	0.6886	0.5900	0.5709	0.6238	0.6031	0.5441	0.5869	0.5831	0.5192	0.5917	0.9426	1.0786	0.8635	0.2162	0.2954	0.2836	0.3506	0.3194	0.2872	0.4967	0.4854	0.4352	0.6807	0.7179	0.7115
Threonine	Threonine	0.2988	0.4690	0.2276	0.5648	0.5364	0.6411	0.3680	0.3486	0.3574	0.5346	0.7890	0.7890	0.9042	0.5842	0.7145	0.3551	0.3779	0.3554	0.6714	0.4361	0.4361	0.4414	0.5147	0.4710	0.7637	0.5175	0.5731	0.3870	0.1636	0.6177	0.1870	0.1586	0.1727	0.5406	0.2899	0.4434	0.9038	0.8836	0.8580	0.1258	0.1116	0.1144	0.2577	0.1269	0.2142	1.4963	1.4364	1.0282	0.1092	0.1141	0.1060	0.2694	0.2729	0.1009	1.0428	0.9963	0.9883	0.9152	0.8382	0.8521	1.0037	0.9471	0.9526	1.0422	0.8884	0.9199	0.6130	0.5880	0.8347	0.7136	0.9010	0.8083	1.0548	1.0213	0.9626	1.0920	0.8127	0.8109	0.9208	0.7624	0.7054
Tryptophan	Tryptophan	0.0432	0.0570	0.0570	0.0378	0.0839	0.0839	0.0291	0.0509	0.0334	0.0424	0.0550	0.0550	0.0865	0.0321	0.0663	0.0228	0.0261	0.0552	0.0531	0.0460	0.0460	0.0125	0.0285	0.0641	0.0414	0.0307	0.0413	0.1100	0.0710	0.0582	0.1100	0.0639	0.0595	0.0773	0.0597	0.0450	0.0541	0.0397	0.0421	0.0588	0.0414	0.0425	0.0520	0.0357	0.0401	0.0781	0.0532	0.0413	0.0410	0.0338	0.0384	0.0558	0.0432	0.0427	0.0682	0.0528	0.0507	0.0497	0.0517	0.0528	0.0749	0.0728	0.0709	0.0603	0.0542	0.0518	0.0737	0.0607	0.0653	0.0473	0.0687	0.0440	0.0588	0.0616	0.0455	0.0791	0.0555	0.0521	0.0562	0.0439	0.0419
Tyrosine	Tyrosine	0.1967	0.2713	0.1485	0.2640	0.2222	0.2554	0.1544	0.1832	0.1353	0.4303	0.4581	0.4581	0.5398	0.5189	0.5796	0.5690	0.5438	0.5056	0.3491	0.3238	0.4238	0.6060	0.4748	0.4380	0.4344	0.4992	0.2655	0.3696	0.4326	0.3015	0.2696	0.1436	0.3054	0.4521	0.3563	0.2653	0.5924	0.3732	0.3797	0.3634	0.3199	0.3778	0.4457	0.3668	0.3999	0.7270	0.5051	0.3773	0.4192	0.4232	0.4358	0.6650	0.5090	0.4172	0.4584	0.4131	0.4293	0.4656	0.3862	0.4016	0.4319	0.3591	0.3907	0.4555	0.4086	0.4157	0.5076	0.4398	0.4125	0.3610	0.4214	0.3645	0.4064	0.4229	0.3347	0.4719	0.3514	0.3820	0.3436	0.4017	0.3994
Valine	Valine	1.5419	1.3922	1.2922	1.3985	1.3307	1.3307	1.3244	1.1824	1.2024	0.5619	0.8699	0.8699	0.8051	0.4521	0.6218	0.4316	0.3198	0.7380	0.7118	0.5201	0.5201	0.5265	0.5184	0.6215	0.6893	0.5225	0.6256	1.1299	1.1955	1.0521	0.6299	0.5066	0.7839	1.1221	1.0179	0.7777	1.1718	0.9165	0.9292	0.7905	0.7959	0.8049	0.8140	0.7499	0.7663	1.2222	0.9327	0.8197	0.7942	0.8099	0.7858	1.3196	0.9828	1.0497	1.2447	0.9665	1.0233	0.8649	0.9018	0.9394	1.0368	0.9234	0.9423	1.0772	0.9817	1.0622	1.0238	0.9829	1.0263	0.7845	0.9856	0.8706	1.0116	0.8992	0.8554	0.8977	0.8813	0.8346	0.8625	0.8099	0.8554