Metabolite_name RefMet_name KO_1_luna.raw KO_2_luna.raw KO_3_luna.raw KO_4_luna.raw KO_5_luna.raw KO_6_luna.raw KO_7_luna.raw KO_8_luna.raw WT_1_luna.raw WT_2_luna.raw WT_3_luna.raw WT_4_luna.raw WT_5_luna.raw WT_6_luna.raw WT_7_luna.raw WT_8_luna.raw Factors - Sample Source:SIRT5 knockout Sample Source:SIRT5 knockout Sample Source:SIRT5 knockout Sample Source:SIRT5 knockout Sample Source:SIRT5 knockout Sample Source:SIRT5 knockout Sample Source:SIRT5 knockout Sample Source:SIRT5 knockout Sample Source:Wild type Sample Source:Wild type Sample Source:Wild type Sample Source:Wild type Sample Source:Wild type Sample Source:Wild type Sample Source:Wild type Sample Source:Wild type 3-Hydroxyisobutyryl-CoA /3-Hydroxybutanoyl-CoA 21614.9482 18715.3517 16633.9803 13312.7388 12756.8334 24828.5703 10391.9384 11054.8804 18285.5171 18131.5328 19326.9032 10041.6199 9916.1665 9959.8095 15933.8574 9946.7301 3-Hydroxyisovaleryl-CoA 3-Hydroxyisovaleryl-CoA 73189.7951 19482.3833 36948.4766 34365.8971 26709.3477 17816.3780 17799.3722 20351.6531 117876.3706 98103.7607 63191.7958 24590.3491 45880.3207 31299.7051 44704.9889 10304.0060 3-Oxo-methylisocapryloyl-CoA 7629.7073 10659.2073 15341.5077 10629.0968 6959.9283 10945.1816 8809.1672 8670.4261 11780.8476 22876.6385 20704.6335 16323.6840 10821.3739 6279.5153 16777.2449 6000.6913 5-Methyltetrahydrofolate 5-Methyl-THF 29511.5549 18725.8126 30533.6895 20498.5469 19657.9012 21088.0626 11793.4505 23208.9292 40721.2435 22611.4361 39310.4936 27816.7478 22547.6069 21778.4088 18314.1022 18251.8642 Acetyl-CoA Acetyl-CoA 104438.7855 130904.9864 123934.5468 92897.0235 67066.5548 251610.2753 219695.2732 102788.2088 60110.8899 87972.9981 110622.0071 37399.2049 75816.2183 78570.0305 156827.3572 115046.2322 Hexanoyl-CoA Hexanoyl-CoA 12793.9914 10674.4332 16103.1197 11249.9561 11053.4377 17611.8319 15641.6323 16511.1291 3561.0412 8197.4813 14828.4759 3229.6589 7071.0129 7215.4570 9311.6446 5278.8773 Isobutyryl-CoA/Butyryl-CoA 50594.3610 43762.7947 58589.7833 55996.7210 49055.6859 92704.4673 86392.8519 99891.3808 11941.9782 37821.6652 43479.0201 20377.3570 34550.6236 29185.3510 42086.1707 29323.8693 Isovaleryl-CoA Isovaleryl-CoA 38585.7297 42479.1005 40560.8320 43673.6582 27393.3082 46809.3263 46635.5004 67010.5233 33222.7585 54679.6701 44423.5976 39923.7524 41694.1866 36181.0428 42937.7297 25542.5475 Malonyl-CoA Malonyl-CoA 2666.6056 989.9396 3630.8418 1056.2954 2810.6483 1174.1388 2039.4582 2908.1493 2528.2931 3855.2589 4187.3277 1933.6341 2560.2491 2548.1885 2927.1663 2285.0596 Propanoyl-CoA Propionyl-CoA 200020.6025 188000.6967 264500.5872 242075.2135 183436.3836 145768.7216 85540.8074 207760.3752 251192.5407 283657.4577 253898.3242 101890.3948 133475.9490 154573.6164 292786.3928 258224.2054 Succinyl-CoA Succinyl-CoA 53245.5496 35899.3567 85962.7104 56693.1499 60097.6739 50155.3417 26213.9267 42139.2575 31740.4901 55764.6194 76203.8874 23176.6943 29296.3740 24085.9651 61805.0599 46364.9242