Metabolite_name	RefMet_name	Evocrp1_1	Evocrp1_2	Evocrp1_3	Evocrp1_4	Evocrp1_5	Evocrp1_6	Evocrp2_1	Evocrp2_2	Evocrp2_3	Evocrp2_4	Evocrp2_5	Evocrp2_6	Evocrp3_1	Evocrp3_2	Evocrp3_3	Evocrp3_4	Evocrp3_5	Evocrp3_6	Evocrp4_1	Evocrp4_2	Evocrp4_3	Evocrp4_4	Evocrp4_5	Evocrp4_6	Evocrp5_1	Evocrp5_2	Evocrp5_3	Evocrp5_4	Evocrp5_5	Evocrp5_6	Crp_1	Crp_2	Crp_3	Crp_4	Crp_5	Crp_6	WT_1	WT_2	WT_3	WT_4	WT_5	WT_6
Factors	-	Genotype:Evolved	Genotype:Evolved	Genotype:Evolved	Genotype:Evolved	Genotype:Evolved	Genotype:Evolved	Genotype:Evolved	Genotype:Evolved	Genotype:Evolved	Genotype:Evolved	Genotype:Evolved	Genotype:Evolved	Genotype:Evolved	Genotype:Evolved	Genotype:Evolved	Genotype:Evolved	Genotype:Evolved	Genotype:Evolved	Genotype:Evolved	Genotype:Evolved	Genotype:Evolved	Genotype:Evolved	Genotype:Evolved	Genotype:Evolved	Genotype:Evolved	Genotype:Evolved	Genotype:Evolved	Genotype:Evolved	Genotype:Evolved	Genotype:Evolved	Genotype:Parent	Genotype:Parent	Genotype:Parent	Genotype:Parent	Genotype:Parent	Genotype:Parent	Genotype:Wildtype	Genotype:Wildtype	Genotype:Wildtype	Genotype:Wildtype	Genotype:Wildtype	Genotype:Wildtype
ADP	ADP	0.6503	0.6374	0.6154	0.6624	0.6640	0.6056	0.5982	0.5949	0.5232	0.5538	0.5963	0.6214	0.4467	0.5447	0.5833	0.5054	0.5818	0.5754	0.4531	0.5118	0.3981	0.4671	0.5540	0.4948	0.5965	0.5834	0.4269	0.5754	0.4650	0.5500	0.5883	0.6125	0.5267	0.6060	0.5146	0.6130	0.4851	0.6268	0.6061	0.6079	0.3327	0.3359
alpha-Ketoglutarate	2-Oxoglutaric acid	1.0878	1.5121	1.0537	1.2108	0.8571	1.5148	0.7757	0.6486	0.7542	0.7501	0.9566	0.8683	0.5167	0.6428	0.6931	0.4818	0.8292	0.7298	1.1041	1.1198	0.8156	0.7838	1.1781	0.7108	0.6842	0.6069	0.9198	0.6334	0.6430	0.5960	0.5469	0.5107	0.2598	0.4312	0.5337	0.6424	0.2185	0.1625	0.3259	0.4226	0.2969	0.3382
AMP	AMP	1.5142	1.7472	1.2325	1.2015	1.7034	1.6302	1.1089	1.1010	1.1248	1.1232	1.1312	1.2650	1.7220	1.7862	1.8611	1.9462	1.9110	2.0266	1.0389	1.1186	0.6312	1.4750	1.0839	1.5468	0.7145	0.5649	0.4567	0.7120	0.4730	0.6435	1.8372	1.2964	1.9015	0.9012	0.7679	1.8267	0.3532	1.0663	0.5783	1.1487	1.2542	1.2401
ATP	ATP	0.4732	0.3639	0.5026	0.4686	0.3841	0.3634	0.5977	0.6038	0.5232	0.3489	0.5716	0.5497	0.2300	0.3138	0.3000	0.2623	0.2952	0.3345	0.4095	0.3629	0.7258	0.2945	0.3851	0.3280	0.7808	0.7838	0.8037	0.7553	0.8402	0.8332	0.3052	0.5126	0.2649	0.7246	0.7531	0.3261	0.9040	0.5189	0.8195	0.5554	0.1515	0.1504
cAMP	3',5' cyclic AMP	0.4285	0.2903	0.4093	0.4275	0.3600	0.2391	0.1887	0.1887	0.0864	0.1003	0.1830	0.0990	0.2043	0.2903	0.3535	0.2138	0.3464	0.3860	0.3219	0.3062	0.8750	0.5001	0.3483	0.4707	0.8726	1.1242	0.5101	0.8410	1.0718	1.3033	2.2169	2.1161	2.0401	3.2951	2.0736	2.3301	0.0424	0.0400	0.0635	0.0472	0.0310	0.0315
Citrate	Citric acid	0.2899	0.3654	0.4002	0.2792	0.4264	0.3274	0.2938	0.3032	0.3722	0.3954	0.2949	0.4277	0.2444	0.3401	0.3874	0.2666	0.3815	0.3868	0.5016	0.2386	0.1890	0.2579	0.2476	0.2580	0.1699	0.1797	0.3424	0.1645	0.2716	0.1680	0.1331	0.1718	0.2728	0.2093	0.1364	0.1419	0.3842	0.4531	0.3615	0.2857	0.1946	0.1966
Fructose-1_6-bisphosphate	Fructose 1,6-bisphosphate	2.2539	2.8146	2.0310	2.8332	2.2680	2.7347	2.6277	3.0466	2.7618	0.7625	2.9950	2.9821	2.1977	2.4139	2.3880	2.4288	2.6977	2.4739	2.9021	0.2950	0.7119	2.6469	2.4860	2.8705	2.0157	0.5784	13.1824	1.9665	2.3644	1.2953	1.7099	1.3947	1.2284	2.0448	1.8927	1.8072	1.6544	2.6201	3.2062	3.1381	2.3595	2.2676
Fructose-6-Phosphate	Fructose 6-phosphate	1.0050	0.9563	0.8083	0.9547	0.9452	0.9426	1.1965	1.2058	1.0553	0.9614	1.1344	1.1844	0.7009	0.8537	0.8871	0.8031	1.0252	0.9540	1.0162	0.9917	1.3181	1.6581	1.2045	1.6089	1.0421	1.0956	4.2411	1.0225	0.7647	1.2389	1.4008	1.1045	0.9816	2.1240	2.1202	1.3432	0.9775	1.4863	1.7161	1.1162	0.7188	1.2670
Glucose-6-Phosphate	Glucose 6-phosphate	1.0043	1.1997	0.9557	0.9367	1.2634	1.0990	1.3431	1.2926	1.3131	1.4514	1.3013	1.4149	0.7742	0.9908	0.9354	0.8459	1.0731	0.9535	1.6021	1.7344	1.3427	2.4994	1.8177	2.6496	1.0522	1.1446	1.9045	0.9897	1.8343	1.1011	1.2100	1.0375	1.1917	1.8712	1.8783	1.2039	0.8738	1.0151	1.0666	0.5804	0.7864	0.7867
Glycerate-3-phosphate	3-Phosphoglyceric acid	0.8605	1.7384	0.7286	0.8550	1.1743	1.5659	1.0941	1.1049	1.2457	1.2027	1.0952	1.3454	0.9169	1.2529	1.3054	0.9834	1.3212	1.3473	1.4346	1.8857	2.7667	2.8866	1.8462	2.8345	2.2927	2.0464	1.6386	2.2617	2.4974	2.5767	2.0628	2.7116	2.2718	2.2235	2.0241	2.2122	0.3102	0.5193	0.4038	1.2879	0.9971	0.9888
Malate	Malic acid	4.3052	6.6597	4.2991	4.2799	4.6936	6.0799	5.9398	5.9709	5.5009	5.7430	5.8321	6.3029	4.4312	4.8179	5.4729	4.7118	5.4182	5.9181	5.6780	5.6412	3.7813	5.2727	5.6662	5.3476	4.5972	3.4310	6.3026	4.5688	3.5192	3.1551	6.9631	6.8794	4.1097	5.0782	5.4814	7.4101	2.3300	1.6996	0.9352	5.8727	3.1298	3.5497
Phosphoenolpyruvate	Phosphoenolpyruvic acid	0.2045	0.5529	0.1962	0.1969	0.1901	0.4985	0.4473	0.4406	0.4442	0.4511	0.4460	0.5020	0.2780	0.3277	0.4268	0.3044	0.3780	0.4244	1.1014	1.1781	4.0828	1.5567	1.1360	1.5637	3.2012	3.2890	3.0487	3.0943	3.3452	3.3186	2.4256	2.0797	2.3280	1.7808	2.0304	2.5583	0.0521	0.0464	0.0499	0.8043	0.2904	0.2861
Pyruvate	Pyruvic acid	1.0043	1.1997	0.9557	0.9367	1.2634	1.0990	1.3431	1.2926	1.3131	1.4514	1.3013	1.4149	0.7742	0.9908	0.9354	0.8459	1.0731	0.9535	1.6021	1.7344	1.3427	2.4994	1.8177	2.6496	1.0522	1.1446	1.9045	0.9897	1.8343	1.1011	0.9767	1.4510	0.5626	1.1337	1.1557	1.0437	0.4478	0.8506	1.3267	1.3856	0.8275	0.8214
Ribose-5-Phosphate	Ribose 5-phosphate	4.6540	10.7919	7.1687	3.3626	8.4650	5.8178	2.3390	2.5996	3.2925	1.9605	3.7990	2.5710	7.1080	9.9149	9.3424	7.7319	20.8613	15.4196	1.5177	1.3982	0.9041	3.1574	4.0593	4.2120	5.6738	2.0383	2.3279	1.9900	0.8013	3.3051	7.4259	4.5166	8.9029	3.7342	4.0548	7.8913	1.0347	2.2842	2.6599	2.3725	1.5455	2.8539