Metabolite_name RefMet_name Beta_10_1 Beta_10_2 Beta_10_3 Beta_10_4 Beta_10_5 Beta_10_6 Beta_10_7 Beta_10_8 Beta_9_1 Beta_9_2 Beta_9_3 Beta_9_4 Beta_9_5 Beta_9_6 Beta_9_7 Beta_9_8 Beta_8_1 Beta_8_2 Beta_8_3 Beta_8_4 Beta_8_5 Beta_8_6 Beta_8_7 Beta_8_8 Beta_8_9 Beta_7_11 Beta_7_12 Beta_7_13 Beta_7_15 Beta_7_3 Beta_7_4 Beta_7_7 Beta_7_8 Factors - Genotype:CUMS model | Treatment:Albiflorin Genotype:CUMS model | Treatment:Albiflorin Genotype:CUMS model | Treatment:Albiflorin Genotype:CUMS model | Treatment:Albiflorin Genotype:CUMS model | Treatment:Albiflorin Genotype:CUMS model | Treatment:Albiflorin Genotype:CUMS model | Treatment:Albiflorin Genotype:CUMS model | Treatment:Albiflorin Genotype:CUMS model | Treatment:Fluoxetine Genotype:CUMS model | Treatment:Fluoxetine Genotype:CUMS model | Treatment:Fluoxetine Genotype:CUMS model | Treatment:Fluoxetine Genotype:CUMS model | Treatment:Fluoxetine Genotype:CUMS model | Treatment:Fluoxetine Genotype:CUMS model | Treatment:Fluoxetine Genotype:CUMS model | Treatment:Fluoxetine Genotype:CUMS model | Treatment:Saline Genotype:CUMS model | Treatment:Saline Genotype:CUMS model | Treatment:Saline Genotype:CUMS model | Treatment:Saline Genotype:CUMS model | Treatment:Saline Genotype:CUMS model | Treatment:Saline Genotype:CUMS model | Treatment:Saline Genotype:CUMS model | Treatment:Saline Genotype:CUMS model | Treatment:Saline Genotype:Wild-type | Treatment:Saline Genotype:Wild-type | Treatment:Saline Genotype:Wild-type | Treatment:Saline Genotype:Wild-type | Treatment:Saline Genotype:Wild-type | Treatment:Saline Genotype:Wild-type | Treatment:Saline Genotype:Wild-type | Treatment:Saline Genotype:Wild-type | Treatment:Saline 1-Methyladenine 1-Methyladenine 73000 93300 92600 85300 145000 73400 65100 85700 65100 49500 21300 109000 113000 124000 121000 97300 68400 70800 98900 91100 74300 190000 122000 86700 151000 128000 96900 116000 118000 75300 126000 113000 103000 1-Methyladenosine 1-Methyladenosine 6150000 4950000 4710000 4910000 4860000 4960000 4880000 4520000 5080000 5850000 1560000 6540000 5830000 6190000 6170000 5730000 6240000 4960000 4580000 6470000 6060000 6550000 6280000 6500000 6850000 6460000 6390000 6700000 4980000 5540000 8420000 5630000 6220000 1-Methylhistidine 1-Methylhistidine 5040000 4230000 5300000 5680000 4970000 3850000 6320000 5380000 9720000 6090000 6330000 6040000 6630000 7020000 6400000 5730000 5150000 4160000 5180000 6050000 5560000 5230000 4440000 6230000 4010000 7410000 7530000 8520000 6140000 8230000 8850000 6760000 8140000 2-Arachidonylglycerol MG 20:4 272000 180000 282000 200000 494000 224000 325000 260000 166000 134000 71400 146000 167000 145000 212000 191000 148000 134000 193000 102000 129000 197000 132000 171000 122000 92800 147000 187000 170000 124000 92300 65900 124000 3-Hydroxydodecanoylcarnitine CAR 12:0;OH 618000 537000 482000 792000 590000 1550000 632000 444000 696000 715000 2290000 690000 619000 778000 638000 641000 641000 574000 756000 562000 771000 667000 709000 668000 792000 1020000 753000 743000 577000 691000 697000 649000 694000 3-Hydroxyisovaleryl Carnitine CAR 4:0;OH,Me 28400000 24300000 20000000 29300000 21200000 22400000 17900000 21200000 22800000 24100000 8400000 22500000 20200000 20100000 23300000 21400000 18500000 27200000 20300000 25600000 23800000 13800000 22400000 25000000 19900000 25600000 18700000 13500000 20000000 35700000 19800000 17900000 21100000 5_6-trans-25-Hydroxyvitamin D3 5,6-trans-25-Hydroxyvitamin D3 6120000 3200000 4290000 5060000 5350000 3430000 6860000 6650000 6630000 7870000 1610000 6950000 8570000 9600000 6560000 5220000 10100000 5030000 7070000 6950000 6720000 13000000 8740000 7910000 8880000 5800000 5570000 5650000 4990000 5950000 4900000 5510000 4720000 5-Hydroxyindoleacetic acid 5-Hydroxyindoleacetic acid 2860000 4060000 2710000 4720000 4380000 3060000 3040000 2200000 3410000 7900000 3600000 4060000 3000000 4310000 3330000 3420000 3620000 3950000 2530000 5430000 6360000 1780000 4700000 5530000 2070000 4400000 2040000 11100000 3710000 2010000 5900000 30400000 3660000 5-Methyltetrahydrofolic acid 5-Methyl-THF 19800 22300 4860 37400 32200 20600 5470 2800 4910 132000 59000 39300 13300 72100 36400 18000 48100 41200 5780 63300 109000 28600 56300 60400 21600 61200 19700 54100 16500 30900 113000 47900 60200 7-ketocholesterol 7-Oxo-cholesterol 4120000 2220000 2650000 3070000 3850000 1940000 4470000 4210000 1910000 3280000 6640000 2490000 2910000 3650000 2200000 2540000 3450000 1900000 2400000 2190000 1950000 6790000 3390000 2950000 4760000 1340000 2010000 1770000 1260000 1330000 958000 846000 710000 8-Hydroxy-deoxyguanosine 8-Hydroxy-deoxyguanosine 72500 72200 58700 67800 73500 53700 64700 44500 86000 82000 324000 156000 57300 87400 65000 83100 74800 78900 58700 82100 98700 68500 87000 76500 113000 81700 119000 73600 66100 41600 133000 104000 80900 Acetylcholine Acetylcholine 47600000 43100000 46300000 51100000 43300000 49800000 53600000 49800000 53900000 48300000 29300000 60900000 57400000 63300000 49600000 47900000 54600000 56600000 52700000 57900000 49200000 53200000 53800000 60300000 44100000 76300000 60100000 69800000 62900000 83300000 63600000 57600000 64700000 Adenine Adenine 1670000 874000 1880000 1160000 1820000 1760000 1990000 1420000 2170000 1360000 537000 1870000 1660000 1940000 1230000 1330000 1810000 1080000 2040000 1370000 1560000 1470000 1420000 1050000 2110000 1640000 1560000 1440000 1240000 1510000 1160000 1330000 1500000 Adenosine Adenosine 21900000 6040000 27800000 9530000 7610000 24600000 32100000 20900000 20400000 19600000 5270000 31800000 28100000 30600000 4950000 4060000 34600000 6800000 27000000 22800000 25100000 9510000 17400000 5340000 36500000 19500000 13200000 17000000 6160000 18700000 6310000 16600000 23000000 Adenosine monophosphate AMP 1270000 1210000 1570000 1100000 1050000 2890000 2720000 2090000 1280000 1340000 1470000 1130000 2780000 1380000 558000 450000 3940000 496000 1770000 1970000 1830000 389000 2190000 2860000 5810000 4630000 1850000 5360000 769000 2320000 1270000 1180000 922000 Alanine Alanine 24200000 25900000 26000000 29000000 30400000 34500000 26800000 22300000 40500000 35900000 38700000 36600000 32100000 37700000 29200000 30000000 33100000 30900000 22400000 29500000 30500000 19300000 30000000 30300000 27000000 43500000 41000000 34200000 32800000 35700000 44300000 36800000 41800000 Alpha-Tocopherol alpha-Tocopherol 1510000 1220000 1330000 1210000 1400000 1180000 1330000 1240000 1380000 1160000 489000 1340000 1570000 1860000 1480000 1860000 1470000 1040000 1620000 1460000 1040000 1490000 1640000 1730000 1500000 1330000 1210000 1230000 1180000 1080000 1230000 1030000 1050000 Biotin Biotin 1640000 1500000 1280000 1120000 1350000 1050000 1230000 1140000 1040000 1090000 887000 955000 993000 901000 1010000 1430000 864000 1040000 976000 872000 1170000 967000 1000000 1190000 1180000 959000 1320000 1240000 1050000 979000 1090000 929000 1180000 Butyrylcarnitine CAR 4:0 19600000 22700000 14900000 14500000 20800000 25900000 23600000 27700000 19100000 20600000 145000000 27200000 19400000 13200000 24300000 29100000 17600000 20300000 19400000 17400000 25400000 22600000 20400000 23000000 14900000 14700000 15900000 13300000 20300000 48400000 16900000 17400000 21100000 Carnosine Carnosine 917000 1080000 822000 1030000 1950000 1290000 177000 302000 537000 1380000 415000 1920000 1010000 2240000 728000 697000 1110000 1450000 371000 545000 434000 162000 593000 714000 370000 830000 992000 836000 1000000 349000 1010000 737000 1360000 Cer(d18:1/18:0) Cer 18:1;O2/18:0 828000 631000 553000 940000 881000 813000 934000 805000 973000 590000 101000 843000 754000 1130000 676000 546000 879000 279000 640000 662000 328000 502000 693000 627000 737000 756000 625000 650000 546000 912000 536000 717000 614000 Cer(d18:1/22:0) Cer 18:1;O2/22:0 924000 617000 522000 1000000 973000 1050000 953000 967000 1200000 746000 165000 1210000 929000 1870000 752000 544000 1300000 463000 952000 667000 655000 749000 702000 865000 1320000 554000 845000 1020000 914000 1130000 1100000 1160000 842000 Cer(d18:1/22:0 OH) Cer 18:1;O2/22:0;O 1070000 656000 638000 1040000 744000 744000 1140000 717000 1000000 689000 140000 869000 1020000 1560000 722000 691000 1060000 378000 1070000 751000 615000 824000 733000 831000 966000 752000 804000 1050000 732000 791000 607000 651000 684000 Cer(d18:1/23:0) Cer 18:1;O2/23:0 944000 716000 697000 1020000 902000 1120000 1090000 924000 1140000 879000 183000 1140000 1020000 1620000 994000 744000 1420000 569000 1200000 787000 866000 962000 917000 959000 1210000 798000 960000 1180000 906000 1150000 1150000 1090000 970000 Cer(d18:1/24:0) Cer 18:1;O2/24:0 2720000 1980000 1160000 2490000 2810000 2630000 2010000 3290000 3150000 2290000 478000 3380000 2260000 4660000 2400000 1750000 3720000 1250000 3010000 1910000 2100000 2670000 2240000 1910000 3350000 1490000 1950000 2830000 2300000 3040000 3130000 3130000 2290000 Cer(d18:1/24:1) Cer 18:1;O2/24:1 9330000 7980000 5600000 8960000 9570000 9180000 9930000 6550000 9100000 7490000 1700000 9720000 8220000 14500000 8380000 5740000 11700000 4630000 8870000 9360000 6100000 9740000 9230000 8610000 11800000 6140000 7600000 9370000 8190000 9760000 7390000 9700000 7790000 Cer(d18:1/24:2) Cer 18:1;O2/24:2 4230000 2690000 2510000 3580000 3510000 3580000 4430000 2060000 4050000 3680000 727000 3740000 4090000 4870000 3690000 2530000 4570000 1760000 3360000 3660000 2550000 3600000 4030000 3600000 4830000 3590000 3870000 4980000 2770000 4160000 2980000 3690000 3940000 Cer(d18:1/25:0) Cer 18:1;O2/25:0 3230000 2970000 2410000 3740000 3340000 3380000 3810000 2110000 3710000 3300000 654000 3510000 3970000 4780000 3150000 2580000 3740000 1670000 3250000 3040000 2300000 3030000 3400000 3350000 4280000 2720000 3380000 4940000 2850000 4200000 2760000 3380000 2950000 Cholesterol Cholesterol 13000000 8500000 10100000 10400000 9740000 8340000 9700000 9900000 6730000 7510000 4300000 4230000 9410000 7930000 8150000 8520000 7300000 5000000 9270000 5170000 6130000 11300000 9990000 8970000 10000000 6830000 10900000 8900000 7170000 6990000 3740000 4330000 6560000 Choline Choline 1730000 1870000 1520000 1710000 1200000 1770000 1550000 1300000 1690000 1920000 2140000 2210000 1430000 2050000 1670000 1330000 1430000 1840000 1460000 2020000 1780000 1600000 1550000 1690000 934000 1980000 1610000 1450000 1690000 1400000 2040000 1300000 1460000 CoQ9 Coenzyme Q9 117000 43400 64500 79600 54900 33000 27900 61500 30700 32700 27200 39000 53800 120000 56500 84900 54200 39500 99800 89700 48600 95500 84400 80400 62000 34500 87200 38600 33600 44500 25900 30900 31900 CoQ9H2 Coenzyme Q9 19500 9960 16300 18700 12700 9270 11000 11200 5640 10000 12500 12600 7800 18100 16800 20500 17700 13300 16200 12800 13000 19600 14400 18300 12300 18500 18900 5910 12500 14000 4220 10300 7130 Corticosterone Corticosterone 857000 712000 629000 807000 759000 763000 677000 431000 445000 782000 266000 475000 751000 683000 792000 914000 778000 499000 617000 737000 760000 478000 659000 552000 896000 1190000 599000 825000 831000 1470000 956000 872000 684000 Cortisol Cortisol 69300 65500 63600 65500 36500 67700 40000 72200 50900 58300 78600 72200 72700 68700 84700 99600 73100 75500 85000 74800 71200 41400 53900 32000 65100 25500 90500 27300 99000 28400 79000 71100 37000 Creatine Creatine 282000000 301000000 304000000 327000000 316000000 341000000 290000000 275000000 323000000 321000000 283000000 328000000 326000000 323000000 306000000 317000000 323000000 314000000 282000000 293000000 307000000 243000000 315000000 306000000 297000000 364000000 353000000 327000000 346000000 340000000 353000000 339000000 364000000 Cysteamine Cysteamine 3040000 3510000 3110000 3360000 3270000 3550000 3430000 3190000 3490000 3350000 2800000 3660000 3260000 3380000 2880000 4210000 3320000 2830000 3010000 3410000 2990000 3230000 3390000 3260000 3660000 2910000 3330000 2960000 3200000 3360000 3370000 3550000 3220000 Cysteine Cysteine 77100 73500 76800 85200 72600 77900 84200 76600 72900 75000 77500 106000 93800 105000 72800 77100 92800 108000 106000 96900 78000 105000 86800 104000 84500 91900 78000 129000 94200 94200 92300 90900 72100 Cysteine-S-sulfate Cysteine-S-sulfate 90300 50900 51700 97800 173000 38300 155000 139000 92100 19600 4160 124000 64000 114000 95500 67900 25800 15500 45400 55100 13700 41800 29800 35200 83200 74800 180000 76900 44000 81100 66100 35300 35600 Cytidine Cytidine 32200000 21800000 16000000 25800000 12600000 15000000 12300000 18700000 26900000 25400000 3630000 21600000 18300000 19600000 28000000 19200000 27400000 23500000 30800000 30700000 39300000 26400000 23100000 33900000 27000000 37500000 23600000 31800000 31600000 45100000 35200000 25100000 29200000 Cytosine Cytosine 129000000 126000000 129000000 131000000 134000000 126000000 135000000 132000000 144000000 147000000 58700000 156000000 154000000 140000000 163000000 132000000 149000000 136000000 146000000 149000000 143000000 157000000 145000000 157000000 161000000 168000000 130000000 166000000 155000000 171000000 158000000 163000000 148000000 Dihexosylcer(18:1/16:0) 76900 66300 164000 135000 83900 100000 115000 79300 260000 227000 75200 94500 161000 240000 95500 147000 239000 114000 105000 211000 104000 83500 183000 134000 187000 127000 130000 128000 160000 132000 91800 102000 264000 Dihexosylcer(18:1/24:1) 22900 5680 24300 13300 14600 14300 11300 9400 44500 20600 18600 16300 39500 32600 18400 21300 23600 19600 13700 16100 11900 10900 18500 18100 20600 14800 14000 19900 16300 20500 13300 19100 31900 Dimethylglycine Dimethylglycine 89200000 84200000 99400000 93000000 95100000 96400000 85300000 108000000 99300000 104000000 78900000 102000000 97300000 103000000 115000000 96200000 105000000 102000000 94400000 99400000 109000000 123000000 122000000 115000000 121000000 109000000 98100000 106000000 84500000 103000000 115000000 112000000 94500000 Dodecanoylcarnitine CAR 12:0 5400000 4540000 4130000 4200000 3010000 2020000 1830000 4980000 2500000 1990000 3680000 2700000 2340000 1900000 4920000 2530000 1480000 2760000 4200000 2760000 4810000 2560000 2150000 3220000 2160000 2510000 2250000 1980000 2100000 5130000 2300000 1820000 3340000 Dodecenoylcarnitine CAR 12:1 2210000 2200000 1570000 1730000 1050000 652000 398000 1990000 849000 824000 2050000 872000 1200000 803000 2030000 1220000 700000 1020000 1950000 1740000 1730000 909000 1030000 1330000 813000 985000 1200000 953000 852000 2550000 1780000 1040000 1650000 Dopamine Dopamine 318000 208000 255000 233000 247000 273000 261000 287000 340000 274000 378000 301000 381000 462000 228000 296000 191000 185000 443000 245000 266000 277000 570000 230000 273000 285000 247000 204000 446000 261000 298000 226000 196000 Epinephrine Epinephrine 281000 347000 340000 269000 353000 307000 255000 345000 362000 323000 134000 429000 311000 283000 355000 369000 283000 393000 299000 341000 277000 290000 282000 319000 281000 224000 275000 292000 296000 447000 339000 265000 283000 Ethanolamine Ethanolamine 3750000 3410000 3520000 3990000 3970000 3920000 3650000 3480000 4930000 3980000 2760000 4410000 3730000 2420000 4040000 3960000 3970000 4570000 3470000 2000000 3240000 3520000 3740000 3900000 3750000 3990000 4190000 3770000 3510000 3120000 5400000 3950000 3050000 Gamma-Aminobutyric acid gamma-Aminobutyric acid 22000 24000 29400 20300 30600 27300 24100 22500 38000 43300 22200 48700 17900 128000 33400 10300 61500 32300 18500 27400 30000 38300 13800 24000 38700 31900 57000 41800 43600 33700 39100 35200 26500 Glucosylceramide(18:1/16:0) 85100 63600 113000 115000 134000 89700 115000 73200 243000 129000 78500 95600 147000 191000 122000 190000 125000 172000 139000 202000 102000 104000 194000 143000 158000 113000 98500 167000 117000 138000 97000 136000 234000 Glycerophosphocholine sn-Glycero-3-phosphocholine 39200000 31600000 39200000 32000000 84700000 38600000 60300000 35500000 37200000 22700000 37900000 32500000 29700000 27100000 56100000 51500000 18100000 46700000 83500000 24800000 26500000 75000000 21200000 20800000 28900000 27500000 40300000 34500000 31500000 43100000 28200000 27000000 26800000 Glycine Glycine 303000 293000 352000 296000 333000 357000 320000 381000 496000 319000 223000 452000 318000 470000 327000 284000 380000 353000 288000 485000 374000 393000 320000 379000 283000 408000 460000 442000 258000 331000 363000 291000 405000 Histamine Histamine 80700000 79400000 79600000 81700000 82000000 77800000 83000000 81600000 87500000 88400000 35200000 95700000 91500000 86600000 97100000 80100000 90000000 84100000 93500000 90800000 86500000 95800000 87800000 96200000 98000000 105000000 79500000 101000000 94900000 105000000 96600000 101000000 91400000 Histidine Histidine 5960000 5450000 6790000 6690000 7470000 6760000 7240000 7140000 10200000 9110000 3010000 8920000 7650000 11000000 7070000 4900000 10500000 8770000 6630000 10100000 8510000 8250000 7170000 9150000 6900000 10200000 7010000 9850000 6450000 9760000 9190000 7780000 8390000 Homoarginine Homoarginine 749000 746000 896000 1040000 873000 1040000 853000 905000 1810000 976000 387000 1160000 950000 1310000 1230000 525000 1190000 1230000 930000 1050000 770000 1140000 9510000 8570000 859000 1460000 1270000 1050000 803000 1590000 1550000 1220000 1090000 Hydroxykynurenine Hydroxykynurenine 814000 803000 807000 904000 979000 906000 951000 924000 1040000 977000 561000 1220000 1220000 1440000 1260000 757000 1220000 1190000 1200000 1150000 1110000 1010000 1130000 1340000 1080000 1180000 943000 1100000 972000 1270000 1150000 1130000 1000000 Hypotaurine Hypotaurine 19100 38100 22200 24100 50900 31100 26500 21600 42300 66400 367000 55100 33300 40700 33400 16800 58900 56100 33600 34000 40300 28300 50000 53100 46900 55700 50800 49500 29200 25000 79400 33800 44000 Indole Indole 1320000 1520000 1130000 1800000 1780000 1740000 1900000 1840000 1950000 1560000 908000 1720000 1730000 1260000 1380000 1300000 1920000 2030000 1670000 3100000 1800000 1110000 2120000 2160000 1210000 1330000 1560000 1560000 1800000 1870000 2220000 2070000 2170000 Isovalerylcarnitine CAR 4:0;3Me 62000000 78700000 58900000 50000000 73600000 75200000 70900000 96300000 76600000 69600000 40200000 73500000 61200000 28600000 54800000 52300000 45800000 79500000 102000000 62700000 109000000 53200000 63400000 63900000 46800000 49700000 44700000 30900000 56700000 134000000 55800000 51300000 47900000 L-Acetylcarnitine CAR 2:0 142000000 171000000 173000000 169000000 164000000 164000000 147000000 170000000 159000000 174000000 177000000 180000000 166000000 165000000 167000000 168000000 167000000 170000000 161000000 173000000 172000000 165000000 166000000 169000000 166000000 163000000 164000000 168000000 168000000 221000000 166000000 166000000 162000000 L-Asparagine Asparagine 847000 946000 794000 798000 1050000 984000 912000 1180000 1520000 1610000 383000 1210000 998000 1390000 872000 620000 1280000 1370000 792000 1120000 1260000 1030000 974000 968000 1030000 1130000 1020000 1220000 768000 1180000 1040000 905000 1130000 L-Carnitine Carnitine 23500000 24500000 24500000 23600000 22800000 24000000 22600000 24600000 26900000 22800000 20000000 25000000 26000000 19700000 25400000 22100000 21700000 25300000 27800000 23400000 26400000 20800000 22800000 24900000 19300000 25000000 21300000 19700000 21900000 28900000 20800000 21900000 21700000 L-Glutamic acid Glutamic acid 3590000 4430000 4700000 4380000 5060000 4890000 4730000 5490000 7970000 5900000 2590000 5610000 5200000 6680000 3430000 3720000 8020000 5950000 5380000 9000000 7360000 4420000 5820000 7530000 5410000 6450000 4820000 6400000 5030000 11600000 8040000 7540000 5910000 L-Glutamine Glutamine 152000000 151000000 145000000 136000000 151000000 137000000 145000000 146000000 166000000 154000000 174000000 150000000 151000000 165000000 144000000 142000000 161000000 158000000 145000000 176000000 167000000 144000000 163000000 160000000 149000000 148000000 155000000 157000000 132000000 155000000 156000000 148000000 152000000 L-Glutarylcarnitine CAR DC5:0 1500000 1530000 1250000 1530000 1350000 1220000 1350000 1460000 1490000 2080000 6320000 1550000 1560000 1460000 1660000 2060000 1340000 1660000 1980000 1400000 1600000 1400000 1470000 1770000 1960000 1730000 2220000 1580000 1450000 2170000 2060000 1730000 1560000 L-Histidinol L-Histidinol 106000 129000 332000 160000 270000 163000 120000 162000 141000 223000 144000 138000 131000 242000 146000 288000 236000 149000 523000 393000 74000 357000 163000 171000 348000 231000 125000 368000 124000 136000 143000 180000 164000 Linoleylcarnitine CAR 18:2 8770000 7740000 10200000 8930000 4160000 4870000 3180000 7640000 5520000 7110000 6600000 6060000 5870000 4750000 16000000 8910000 4830000 5980000 7220000 6610000 9840000 5140000 3850000 6280000 3380000 9620000 9200000 8120000 6610000 26200000 6930000 4540000 14300000 L-Kynurenine Kynurenine 316000 307000 265000 288000 274000 518000 333000 339000 470000 306000 130000 282000 286000 325000 372000 310000 324000 417000 330000 544000 547000 269000 414000 458000 345000 423000 288000 339000 393000 429000 1670000 293000 872000 L-leucine Leucine 157000000 162000000 157000000 161000000 167000000 163000000 176000000 186000000 220000000 195000000 84600000 162000000 156000000 178000000 157000000 164000000 188000000 184000000 162000000 229000000 185000000 174000000 182000000 186000000 183000000 170000000 164000000 183000000 152000000 192000000 180000000 171000000 179000000 L-Methionine Methionine 17200000 19700000 18100000 21300000 19900000 21200000 20100000 22500000 32900000 26000000 11600000 21500000 17700000 20900000 21100000 18900000 22400000 23300000 15600000 29500000 26500000 16500000 22600000 23900000 19000000 23500000 25500000 27900000 21800000 21400000 26300000 24000000 25600000 L-Palmitoylcarnitine CAR 16:0 899000 395000 384000 879000 202000 255000 272000 373000 294000 459000 626000 305000 282000 231000 544000 287000 320000 354000 371000 376000 509000 299000 273000 354000 435000 338000 748000 300000 316000 767000 352000 258000 384000 L-Phenylalanine Phenylalanine 30600000 35300000 34800000 37200000 33800000 33800000 42100000 41400000 58900000 41000000 15500000 37000000 35500000 35800000 35900000 33000000 35400000 40100000 34000000 53200000 40300000 34800000 39700000 39800000 36000000 34900000 38700000 38600000 34300000 42800000 40300000 36200000 40300000 L-Serine Serine 4070000 5100000 5320000 4960000 5520000 4620000 4690000 6400000 7020000 6780000 2410000 5750000 4310000 6410000 4630000 3260000 5970000 5700000 3990000 6220000 4830000 4300000 4500000 4960000 4250000 5700000 5210000 5280000 3080000 6510000 5390000 4270000 4510000 L-Tryptophan Tryptophan 53600000 32400000 28000000 57300000 54600000 57100000 63100000 62800000 62800000 64500000 39700000 59200000 57600000 44600000 49500000 51800000 61600000 69000000 49600000 95100000 85100000 41400000 68800000 69300000 40000000 56400000 54200000 48700000 58400000 84000000 61700000 67800000 65700000 L-Tyrosine Tyrosine 937000 938000 1070000 1210000 775000 872000 1230000 1330000 2020000 1190000 951000 1020000 1290000 1450000 985000 918000 1640000 1510000 909000 2020000 1680000 1190000 1590000 1320000 1020000 1330000 1280000 1650000 1140000 1750000 2250000 1250000 1590000 L-Valine Valine 888000 976000 987000 969000 1250000 1180000 1300000 1270000 2030000 1670000 542000 1320000 1060000 1440000 1020000 1140000 1640000 1460000 1070000 1940000 1470000 1380000 1500000 1450000 1320000 1260000 1170000 1400000 973000 1290000 1330000 1120000 1250000 Lysine Lysine 116000000 114000000 118000000 115000000 122000000 114000000 118000000 121000000 151000000 134000000 94300000 128000000 130000000 145000000 121000000 108000000 143000000 141000000 117000000 158000000 142000000 123000000 143000000 138000000 124000000 118000000 121000000 135000000 108000000 125000000 134000000 129000000 130000000 LysoPC(16:0) LPC 16:0 33200000 35600000 36300000 34700000 37400000 33000000 35300000 34900000 36600000 43500000 33400000 36100000 32800000 42200000 35400000 36200000 36000000 36400000 34300000 38800000 36800000 38700000 40600000 36300000 35200000 31800000 30900000 35300000 35800000 34300000 33600000 33400000 33500000 Malonylcarnitine CAR DC3:0 21500000 15700000 12800000 21300000 8880000 12700000 7850000 9050000 9980000 20900000 12500000 16700000 10300000 14400000 11100000 14500000 14000000 13100000 6250000 14700000 21600000 4520000 12900000 17400000 7360000 15800000 12100000 10700000 12800000 30300000 14700000 12400000 21800000 Melatonin Melatonin 123000 215000 134000 102000 172000 184000 153000 270000 134000 248000 142000 220000 144000 62000 170000 139000 124000 126000 117000 101000 278000 142000 195000 189000 71600 85700 111000 61300 145000 473000 112000 177000 106000 Metanephrine L-Metanephrine 969000 1220000 772000 1030000 1020000 914000 832000 877000 1160000 1210000 1980000 983000 960000 822000 1320000 1340000 1060000 946000 1120000 584000 678000 1230000 874000 953000 1950000 1300000 1150000 945000 1170000 1270000 1180000 1250000 1080000 Methionine sulfoxide Methionine sulfoxide 299000 261000 325000 306000 382000 383000 551000 545000 1140000 468000 336000 523000 526000 492000 371000 294000 380000 418000 516000 464000 245000 425000 318000 406000 513000 381000 438000 339000 320000 719000 422000 376000 242000 Myristoylcarnitine CAR 14:0 11400000 9390000 10000000 10500000 5340000 4400000 3130000 10500000 4820000 4490000 5900000 5740000 5100000 4040000 13700000 6300000 3470000 5730000 8650000 6750000 10600000 6340000 4860000 7510000 4750000 6860000 6300000 6170000 4500000 15000000 5470000 4450000 9710000 N-alpha-Acetylarginine Pelargonidin 623000 1070000 887000 1320000 962000 650000 1090000 802000 2190000 1080000 181000 686000 995000 1420000 1710000 1160000 615000 562000 881000 759000 1300000 755000 801000 1640000 512000 1570000 1770000 2150000 581000 2570000 2210000 1460000 3000000 Niacinamide Niacinamide 72400000 74000000 73500000 75900000 76300000 82300000 50400000 62700000 89300000 77900000 65500000 72400000 79700000 77700000 78600000 70900000 48800000 50400000 59700000 56900000 58100000 46000000 53600000 68700000 63800000 102000000 76200000 76100000 72300000 130000000 77100000 60400000 73100000 Nicotinamide N-oxide Nicotinamide N-oxide 21700000 28800000 25100000 19000000 18800000 21800000 16800000 20700000 30700000 27900000 15900000 26800000 23600000 29300000 27700000 20700000 20700000 19100000 21100000 26100000 25500000 22400000 24400000 22700000 22800000 24900000 21900000 23900000 25300000 24300000 31600000 23800000 24700000 N-oleoylethanolamine Oleoyl-EA 852000 614000 654000 719000 554000 561000 606000 633000 414000 423000 158000 473000 447000 471000 528000 383000 440000 381000 555000 469000 571000 479000 456000 436000 427000 499000 424000 525000 573000 498000 394000 344000 471000 Norepinephrine Norepinephrine 112000 124000 149000 274000 137000 135000 124000 130000 144000 154000 146000 245000 174000 326000 159000 213000 132000 228000 159000 283000 174000 162000 171000 171000 174000 158000 167000 133000 220000 131000 187000 209000 127000 Normetanephrine Normetanephrine 1800000 1960000 1350000 1900000 2120000 1530000 1920000 1640000 2280000 1910000 1110000 2360000 2060000 3080000 3300000 1960000 2080000 2030000 1870000 1990000 1660000 1870000 2440000 2590000 1760000 1500000 1450000 2240000 1670000 1410000 3460000 2270000 2680000 Octadecanoylcarnitine CAR 18:0 6470000 5050000 7310000 7070000 4090000 4810000 3630000 5280000 5160000 4730000 4070000 4890000 4990000 3440000 6960000 5740000 3990000 4470000 6070000 6340000 7060000 4290000 4080000 5020000 3700000 6690000 6870000 6070000 5340000 11300000 4700000 4230000 9570000 Oleoylcarnitine CAR 18:1 21100000 14600000 21600000 19000000 8300000 8890000 6620000 18400000 10100000 10300000 10100000 9380000 10400000 8080000 26200000 14400000 7470000 10800000 14400000 13200000 19500000 8910000 6930000 11400000 6100000 16000000 16100000 13200000 11800000 40700000 11200000 8250000 23400000 Ornithine Ornithine 82600 91800 147000 223000 155000 135000 124000 153000 359000 184000 156000 138000 106000 144000 106000 88800 154000 198000 92500 217000 152000 92300 128000 186000 94100 219000 92500 136000 87900 115000 183000 111000 177000 Oxidized glutathione Oxidized glutathione 7400 8000 9730 5740 8110 7800 3420 6100 12300 22200 16800 10900 5940 11000 6170 8570 17200 16500 3790 16700 8420 3390 15400 18000 5990 6620 5290 7890 8920 4580 1790 5460 14800 PC(16:0/16:0) PC 16:0/16:0 8910000 8020000 8950000 8550000 9130000 11200000 11600000 9250000 12900000 12300000 20300000 13200000 12500000 13500000 8660000 8840000 13100000 8270000 11800000 11800000 10900000 11000000 11300000 11800000 12900000 14000000 9930000 15600000 9850000 13800000 9900000 11900000 12500000 PC(16:0/18:1) PC 16:0/18:1 9840000 11400000 8800000 9210000 11600000 10400000 10900000 13400000 12800000 12100000 24300000 13200000 10500000 15600000 9760000 11500000 12100000 10400000 12100000 12000000 8080000 14700000 11600000 10500000 11400000 8320000 7530000 9530000 7390000 8850000 7550000 8010000 7300000 PC(16:0/18:2) PC 16:0/18:2 7490000 8010000 7520000 8750000 8930000 9280000 8650000 7900000 9740000 10500000 17200000 11000000 10000000 11000000 8260000 10200000 12200000 9890000 10600000 10000000 6950000 11600000 10700000 9970000 11900000 7440000 7870000 8900000 6970000 8500000 8120000 7750000 7410000 PC(16:0/20:4) PC 16:0/20:4 4850000 4150000 3880000 5490000 4740000 3930000 5390000 3160000 4870000 5160000 10600000 5630000 4580000 5570000 4310000 5430000 5480000 4590000 5060000 5180000 5060000 5010000 4310000 5260000 5230000 4400000 4080000 5240000 3740000 4030000 5090000 4670000 4860000 PC(16:0/22:6) PC 16:0/22:6 2810000 1140000 2010000 2080000 2120000 1570000 2070000 1220000 1870000 2010000 4310000 2140000 1380000 2530000 1810000 2370000 2280000 1270000 2020000 2420000 2460000 1970000 1550000 2270000 1700000 2170000 1660000 1830000 1650000 1700000 1780000 1390000 2280000 PC(18:0/18:2) PC 18:0/18:2 10500000 10700000 11000000 12100000 12300000 12800000 12200000 11400000 16200000 13200000 26600000 16000000 14200000 14500000 12700000 17200000 18500000 15100000 16000000 16200000 12900000 17700000 19700000 15000000 19600000 12100000 13800000 12700000 10200000 13300000 13100000 13800000 12300000 PC(20:4/P-16:0) PC P-16:0/20:4 or PC O-16:1/20:4 660000 585000 659000 839000 583000 608000 725000 668000 880000 694000 1530000 849000 971000 844000 849000 966000 842000 622000 775000 682000 628000 659000 641000 946000 722000 922000 748000 826000 823000 909000 745000 648000 802000 PC(22:6/P-18:0) PC P-18:0/22:6 or PC O-18:1/22:6 90100 67600 70200 72100 83600 63500 83500 73200 90500 60600 192000 126000 71200 98200 74500 114000 75700 43100 162000 83300 54500 70000 56400 81400 67500 65100 74400 83100 66100 80900 62200 88500 74700 Phosphorylcholine Choline phosphate 1860000 1800000 1280000 1850000 1530000 2140000 1150000 1310000 3150000 4680000 2050000 2090000 2630000 3050000 2490000 2080000 3590000 1980000 2360000 3780000 2630000 1470000 2160000 3870000 3330000 4300000 2500000 5470000 1410000 4020000 2300000 3560000 2810000 Pipecolic acid Pipecolic acid 121000000 108000000 117000000 128000000 130000000 123000000 123000000 126000000 159000000 145000000 45900000 136000000 141000000 164000000 143000000 102000000 148000000 131000000 132000000 156000000 129000000 133000000 141000000 147000000 130000000 133000000 135000000 153000000 105000000 139000000 142000000 136000000 140000000 Propionylcarnitine CAR 3:0 50500000 55400000 46100000 49500000 53900000 89700000 65700000 58300000 55700000 79700000 80300000 70300000 68100000 48000000 53600000 72000000 84100000 60000000 56700000 61200000 78400000 51900000 67400000 64700000 84100000 60200000 48800000 45900000 53500000 94700000 42100000 56200000 42700000 Purine Purine 577000 583000 577000 576000 644000 475000 727000 695000 1030000 706000 169000 621000 645000 577000 652000 510000 711000 747000 564000 1010000 673000 573000 676000 738000 604000 593000 617000 564000 601000 748000 700000 602000 704000 Retinal Retinal 80700 59300 98900 73600 57000 72100 95000 74000 65200 57700 47100 77000 116000 54500 107000 42400 34100 40900 71900 65900 55400 50500 51400 53400 49800 89700 99000 42900 86800 89600 71900 82300 70700 Retinol Retinol 49900 28400 46800 26600 24900 49900 41800 32800 28700 42000 63400 29200 34400 40000 45100 41700 43600 42500 27900 52600 52000 69400 35900 37000 30200 32800 27100 39000 32300 34400 64200 187000 41700 Riboflavin Riboflavin 25400 49100 45600 49900 28700 42700 27200 35400 133000 140000 41000 133000 88300 126000 62100 77100 103000 101000 113000 158000 84900 148000 68400 134000 69200 120000 90100 131000 83700 141000 60500 91100 120000 Saccharopine Saccharopine 510000 447000 478000 510000 548000 509000 504000 494000 1350000 531000 1390000 528000 519000 788000 489000 457000 610000 600000 516000 712000 638000 489000 708000 656000 471000 563000 562000 572000 461000 485000 775000 530000 677000 S-Adenosylmethionine S-Adenosylmethionine 10500 5450 5360 7240 4490 5830 3670 5000 2980 10500 13100 6330 4080 4700 9300 6190 6530 10200 5240 9160 6720 6780 6380 7390 7250 5110 5130 5950 4280 6540 12300 8670 3670 Sarcosine Sarcosine 30800000 32900000 32600000 35400000 36300000 40700000 32300000 27900000 49700000 43000000 45200000 41500000 39800000 46100000 34100000 37100000 41000000 39500000 29300000 35600000 35000000 24500000 36600000 36700000 34300000 51800000 50100000 42600000 39100000 41400000 51800000 44700000 50800000 Serotonin Serotonin 859000 680000 840000 836000 477000 1210000 1260000 828000 305000 361000 265000 414000 402000 369000 289000 125000 1960000 550000 1310000 1210000 1370000 530000 1320000 1320000 2160000 2070000 1200000 2540000 378000 1700000 917000 1420000 1360000 Spermidine Spermidine 139000 80800 128000 118000 171000 166000 167000 133000 136000 125000 63300 141000 146000 118000 150000 137000 121000 129000 172000 135000 155000 132000 160000 135000 141000 115000 142000 66400 105000 132000 146000 148000 137000 Suberylcarnitine CAR DC8:0 2010000 1910000 2150000 2010000 2220000 2070000 2200000 2240000 1640000 2840000 4610000 2350000 2380000 2790000 2590000 2360000 2760000 2840000 2360000 2400000 2470000 2580000 2380000 2720000 2800000 3210000 3010000 3270000 2040000 2800000 2450000 2270000 2610000 Testosterone Testosterone 451000 275000 164000 146000 95700 135000 139000 59400 94700 204000 173000 132000 170000 159000 137000 229000 259000 133000 124000 179000 136000 125000 168000 189000 137000 261000 192000 242000 205000 146000 209000 126000 168000 Thiamine Thiamine 230000 370000 224000 310000 144000 468000 132000 292000 468000 557000 102000 315000 212000 412000 280000 80800 910000 350000 133000 494000 668000 265000 625000 886000 359000 198000 230000 372000 301000 128000 1360000 529000 414000 Trihexosylcer(18:1/16:0) 23100 19700 39900 29500 40300 30200 47200 16200 62300 36000 19900 28900 48100 66500 35000 36800 35700 43400 31900 58300 21900 35000 31000 38800 41800 59500 40900 47900 35100 45200 32900 43800 48800 Trimethylamine-N-oxide Trimethylamine N-oxide 130000000 130000000 102000000 120000000 195000000 154000000 135000000 132000000 194000000 38500000 111000000 215000000 121000000 212000000 43400000 178000000 156000000 142000000 134000000 160000000 139000000 157000000 152000000 178000000 169000000 24300000 60500000 68500000 46000000 104000000 133000000 195000000 157000000 Urea Urea 38000000 39200000 40100000 42700000 41600000 45500000 45500000 43100000 47100000 47700000 33100000 49600000 45300000 45200000 40100000 44600000 41500000 36900000 41700000 41400000 36600000 42800000 44400000 43000000 43600000 44800000 44500000 41200000 46800000 46300000 44400000 45700000 42400000 Vitamin D3 Vitamin D3 1250000 901000 1070000 1090000 1280000 1000000 1260000 1420000 1150000 1210000 3520000 1090000 1640000 1540000 1420000 1300000 1110000 821000 1480000 1110000 1200000 1400000 1340000 1240000 1220000 1370000 1290000 1080000 1190000 1260000 1080000 918000 1040000 Vitamin K2 Vitamin K2 1390000 920000 5070000 990000 1890000 1310000 2860000 1430000 1690000 1210000 758000 1630000 2150000 1780000 1830000 11600000 1030000 1450000 3770000 1310000 965000 3300000 1400000 1220000 3040000 1750000 2990000 1590000 4430000 1200000 1220000 1060000 1170000