Metabolite_name RefMet_name S00025568 S00025577 S00025578 S00025579 S00025571 S00025573 S00025574 S00025580 S00025570 S00025581 S00025575 S00025576 S00025572 S00025569 Factors - Gender:female | Glycemic status:diabetic | Neuropathy:Neuropathy Gender:female | Glycemic status:diabetic | Neuropathy:Neuropathy Gender:female | Glycemic status:diabetic | Neuropathy:Neuropathy Gender:female | Glycemic status:diabetic | Neuropathy:Neuropathy Gender:female | Glycemic status:diabetic | Neuropathy:no neuropathy Gender:female | Glycemic status:diabetic | Neuropathy:no neuropathy Gender:female | Glycemic status:diabetic | Neuropathy:no neuropathy Gender:female | Glycemic status:diabetic | Neuropathy:no neuropathy Gender:female | Glycemic status:normoglycemic | Neuropathy:Neuropathy Gender:female | Glycemic status:normoglycemic | Neuropathy:no neuropathy Gender:male | Glycemic status:diabetic | Neuropathy:Neuropathy Gender:male | Glycemic status:diabetic | Neuropathy:no neuropathy Gender:male | Glycemic status:pre-diabetic | Neuropathy:Neuropathy Gender:male | Glycemic status:pre-diabetic | Neuropathy:no neuropathy 16:0-18:0 PC (M+CL)- PC 16:0_18:0 14442 14983 11957 12357 12063 15892 14135 16924 8900 8639 16354 14534 20505 14343 16:0 LYSO PC (M+CL)- LPC 16:0 19749 44690 43905 46589 19226 36465 36050 19818 15840 18648 15435 12895 14497 16453 18:0 LYSO-PE (M-H)- LPE 18:0 8999959 751180 380849 730637 810238 1067215 867050 1-METHYLADENOSINE (M+CL)- 1-Methyladenosine 3872 1787 3015 2144 2444 2499 2302 1786 2947 1-METHYLURIC ACID (2M-H)- 1-Methyluric acid 9819 3108 11239 2381 7712 7808 1-METHYLURIC ACID (M-H)- 1-Methyluric acid 129094 76583 170951 48423 8843 161686 54422 38625 58104 133950 147326 42829 1-METHYLXANTHINE (M-H)- 1-Methylxanthine 631267 733189 30207 242052 3308 5955 557084 350362 23443 842843 579198 206031 21161 24:0 SM (D18:1/24:0) (M+CL)- SM 18:1;O2/24:0 1273412 196240 207046 238209 6911213 262146 2397635 391113 195694 204665 1552542 2-DEOXY-D-GLUCOSE (M+CL)- 2-Deoxy-glucose 21682 12084 26925 1718 4751 3396 654 786 1963 92130 28881 7220 57869 8620 2-HYDROXY-3-METHYLBUTYRIC ACID (M-H)- 2-Hydroxy-3-methylbutyric acid 531198 630243 205398 710508 1130087 502943 347589 648551 581085 581538 489833 3083399 360160 587132 2-HYDROXYBUTYRIC ACID (M-H)- 2-Hydroxybutyric acid 139521 143411 239986 293085 627523 296726 113288 424885 266789 111010 425289 255107 172239 168868 2-METHYLMALEIC ACID (M-H)- Citraconic acid 21156 66594 24886 32519 5186 42511 11904 12706 11361 14868 22635 24777 3-(4-HYDROXYPHENYL)LACTIC ACID (M-H)- Hydroxyphenyllactic acid 22305 11511 21974 17858 15869 15655 37350 3-HYDROXY-3-METHYLGLUTARIC ACID (M-H)- 3-Hydroxymethylglutaric acid 200077 270346 339148 204748 366565 370238 334996 297243 185814 297637 444348 92772 171266 3-METHYL-2-OXOPENTANOIC ACID (M-H)- 3-Methyl-2-oxovaleric acid 2105333 1759509 3905035 3292590 4225698 3264361 2166137 2835154 3407324 1843412 2663969 3344586 3799366 3213327 3-METHYLXANTHINE (M-H)- 3-Methylxanthine 630824 732981 61554 241973 204598 1111 556833 350258 158228 842255 578913 169363 99007 4-METHYL-2-OXOPENTANOIC ACID (M-H)- Ketoleucine 2688757 2372537 5523247 4574641 5959610 4117889 2889528 4688088 4860324 2925346 4370131 3658898 4978358 4733050 4-PYRIDOXIC ACID (M-H)- 4-Pyridoxic acid 167092 108179 443475 306942 288866 64290 333651 192568 80108 85236 77543 97634 347341 69933 5-HYDROXY OMEPRAZOLE (M-H)- 5-Hydroxyomeprazole 42987 23358 ACETAMINOPHEN (TN TYLENOL) (M-H)- Acetaminophen 51715 ADIPIC ACID (M-H)- Adipic acid 39243 26315 104893 25805 62654 36339 90209 49769 37746 39165 33125 37034 25509 29204 ARACHIDONIC ACID (M-H)- Arachidonic acid 1783818 259771 394915 339114 254586704 1609570 1212459 21653312 554227 311928 225535 2050652 AZELAIC ACID (M-H)- Azelaic acid 13890 12547 28889 17421 18145 335392 11609 12661 13176 11664 12379 27307 16694 13634 CHOLIC ACID (M-H)- Cholic acid 6062 24840 2308 1710 25220 37344 3983 CIS-11-EICOSENOIC ACID (M-H)- cis-Gondoic acid 19411 1587 4105 3179 86737 33219 16510 12782 97920 8518 3023 1032 76552 22074 CITRAMALIC ACID (M-H)- Citramalic acid 95801 35912 202448 62185 81590 147161 43113 26497 28359 32425 56812 42308 45863 CITRIC ACID (M-H)- Citric acid 2235964 3725230 3504557 3023461 1759606 40983 2223393 3314008 1810542 2752488 1778230 2367852 1685619 1887933 CORTISOL (M+CL)- Cortisol 78426 24979 25375 64253 50354 81860 16736 41710 30619 30233 30610 53510 29111 49128 CORTISONE (M+CL)- Cortisone 20064 10185 7160 18073 11624 27036 12566 10980 15343 15891 35050 16768 24424 DEHYDROEPIANDROSTERONE SULFATE (M-H)- Dehydroepiandrosterone sulfate 517676 572063 79107 267842 1635875 1921093 76111 714839 1521235 1030372 465548 241755 428340 790904 DEOXYADENOSINE (M+CL)- Deoxyadenosine 13522 19866 13391 30769 45976 21209 10024 36463 25953 14378 37231 22085 13846 21132 DEOXYCHOLIC ACID (2M-H)- Deoxycholic acid 3454 2889 1680 1968 2733 6269 1897 DEOXYCHOLIC ACID (M+CL)- Deoxycholic acid 18561 5276 2704 16919 12197 6710 13120 6949 1346 18636 25823 6194 5714 13022 DEOXYCHOLIC ACID (M-H)- Deoxycholic acid 48555 15343 6621 46404 33321 20621 35422 19163 3180 46552 69049 17311 18321 35473 DEOXYURIDINE (M+CL)- Deoxyuridine 44825 54689 76264 75334 71526 153950 102650 87024 51099 73631 80462 60446 111668 87221 DIPALMITOYL PHOSPHATIDYLETHANOLAMINE (M-H)- PE 16:0/16:0 35638 19218 21239 18778 95561 19652 42333 22356 22084 36550 17409 13189 27117 25212 DOCOSAHEXAENOIC ACID (M-H)- Docosahexaenoic acid 1881438 569331 402559 364191 3495245 1156002 418444 790045 261226 3325228 EPIBRASSINOLIDE [ISTD] (M+CL)- 24-epi-Brassinolide 406901 394047 390628 379730 444477 393048 420025 394709 448948 400629 384164 371205 432900 388915 GALACTARIC ACID (M-H)- Galactaric acid 7590 10192 10330 9471 9985 10435 GLUCONIC ACID (M-H)- Gluconic acid 5223 5217 2012 9515 4065 2678 2963 5934 5107 6911 4968 9023 3962 4451 GLUCOSE (M+CL)- Glucose 591315 746681 232309 669312 676231 1231678 370314 708559 831843 767110 666707 701284 685356 722689 GLYCOCHOLIC ACID (M-H)- Glycocholic acid 11924 10998 1213 34259 5802 14689 11741 38809 20944 256524 14702 16687 12218 11735 HIPPURIC ACID (M-H)- Hippuric acid 140384 117274 266015 189693 22778 54534 194965 57697 41141 24716 311531 2719288 256113 79530 HYODEOXYCHOLIC ACID (M-H)- Hyodeoxycholic acid 190518 55983 73154 56928 272228 193196 134941 114084 275784 113781 80647 28294 247116 88086 IBUPROFEN CARBOXYLIC ACID (M-H)- 1689 58954 206531 457492 5032 IBUPROFEN (M-H)- Ibuprofen 14263 36323 382483 ISOCITRIC ACID (M-H)- Isocitric acid 19435742 59247456 26541320 17417600 9652640 103716248 L-[15N]ANTHRANILIC ACID [ISTD] (M-H)- 2-Aminobenzoic acid 69023 84762 91958 89820 65769 56681 57241 81808 70215 74400 83673 96352 65223 72345 LINOLEIC ACID (M-H)- Linoleic acid 830606 56339 151683 158794 793276 262255 200027 302100 1421896 226628 95495 82386 795705 519891 L-TRYPTOPHAN-15N2 [ISTD] (M-H)- Tryptophan 51573 69506 75161 63580 69079 61057 50826 73541 71761 68163 57529 44660 69380 72430 MALIC ACID (M-H)- Malic acid 138658 58119 28022 63525 74548 4532 67848 83983 90200 66943 55349 75169 70942 82394 METHYLMALONIC ACID (M-H)- Methylmalonic acid 67455 59494 72024 66054 73019 23978 56098 66302 53364 86328 80602 23692 97667 56036 MYRISTIC ACID (M-H)- Myristic acid 36591 3926 6846 5478 73748 24949 17353 505176 19011 7723 1701 63636 MYRISTOLEIC ACID (M-H)- Myristoleic acid 1918 7132 31493 13483 2014 1568 13132 3094 8299 3767 2001 N-ACETYL-D-GLUCOSAMINE (M+CL)- N-Acetyl-D-glucosamine 6480 15024 6609 7847 32837 2374 10309 17981 10160 10464 8840 N-ACETYL-L-ALANINE (M-H)- N-Acetylalanine 209869 170127 184084 173354 209348 222261 156608 302722 219346 113873 222257 138631 174931 188103 NERVONIC ACID (M-H)- Nervonic acid 20571 1157 2397 2099 4491 4119 1730 1082 89467 OLEIC ACID (M-H)- Oleic acid 1518948 94771 256132 175677 3386292 898190 682608 503026 5387791 403031 113297 33475 1951407 1209034 OXALOACETIC ACID (M-H)-[-H2O] Oxaloacetic acid 16429 18560 17653 8891 18398 44665 25697 12963 17312 4611 8759 19399 15714 P-ACETAMIDOPHENYL BETA-D-GLUCURONIDE (M-H)- p-Acetamidophenylglucuronide 10630 698544 PALMITIC ACID (M-H)- Palmitic acid 121373 11250 19879 14019 178393 61486 49106 45233 336483 46227 7990 3270 128595 114025 PALMITOLEIC ACID (M-H)- Palmitoleic acid 353072 13922 40435 23347 380849 133651 101682 91116 23179 3037 300695 PANTOTHENIC ACID (M-H)- Pantothenic acid 17066 12408 47828 32867 38081 15371 18286 25777 9300 11182 6002 16736 10374 PHENYLALANINE (M-H)- Phenylalanine 335078 251646 47272 346564 546238 640282 293989 459906 538395 348554 458618 414414 609374 692295 PHENYLPYRUVIC ACID (M-H)- Phenylpyruvic acid 1137 1171 396 8148 3801 4941 1395 1179 9494 5857 PYRUVIC ACID (M-H)- Pyruvic acid 3958 20380 7044 72750 18195 4024 39049 23978 14403 110183 41843 49635 RIBITOL (M+CL)- Ribitol 185200 160085 191896 101850 187621 169178 163375 156611 212759 147762 145930 136169 165682 161770 S-ADENOSYL-L-HOMOCYSTEINE (M-H)- S-Adenosylhomocysteine 4231 1800 7060 8702 5721 5954 4505 3849 2936 2305 4359 7847 4507 SALICYLATE #2 (M-H)- Salicylic acid 18203 788517 24754 16122 8925 87666 87379 19251 29103 149877 2945322 17580 709408 148846 SALICYLURIC ACID (M-H)- Salicyluric acid 38933 4149 5710 4401 137536 46661 5761 STEARIC ACID (M-H)- Stearic acid 184770 15913 23998 23395 638477 132257 63785 60934 761736 56284 22675 12094 537921 221712 SUCCINIC ACID (M-H)- Succinic acid 184935 151425 184026 74065 183170 161489 92912 153470 193229 143824 143442 183079 162076 161248 SUCROSE (M+CL)- Sucrose 3622 4006 4378 2520 1944 3232 4962 3352 4347 2997 2647 SULFADIMETHOXINE (M-H)- Sulfadimethoxine 17795 13800 16462 11658 15219 13298 12894 6837 18744 7632 12903 11443 16622 23709 THEOPHYLLINE (M-H)- Theophylline 50973 209694 90285 59087 5488 41004 188373 33191 92317 62688 98418 2188 12300 THYROXINE (M-H)- Thyroxine 5772 4130 5818 3555 3890 3109 5569 5171 4404 3591 3923 3986 3811 3682 TRANS-ACONITIC ACID (M-H)- trans-Aconitic acid 875042 1203703 3515377 1568590 1780286 3391714 1928719 916636 968275 1957160 2622574 1190335 859600 TRYPTOPHAN (2M-H)- Tryptophan 55323 113644 110041 90423 113159 130361 67289 105663 104346 105018 102225 50147 169031 157842 TRYPTOPHAN (M-H)- Tryptophan 336127 611914 599029 513459 567397 617223 380630 571262 555471 564685 539977 313116 749637 739039 TYROSINE (M-H)- Tyrosine 32185 38974 16983 39030 22934 48167 18119 29659 32419 41342 40419 35489 52503 61969 URIC ACID (M-H)- Uric acid 1603566 1432633 785874 1114695 1707436 1651663 1192640 1297313 1386702 1679687 1632712 1245060 1582693 1755934 URIDINE (M+CL)- Uridine 3137207 4450638 1558782 2318525 4320724 2735655 2983165 4888274 5288411 4366741 4341873 1049430 4659748 5376756 URIDINE (M-H)- Uridine 135628 53250 57288 131060 125594 232815 48636 1517407 XANTHINE (M-H)- Xanthine 106959 142883 57573 124089 95270 276657 60186 118545 134385 121436 140166 183399 225985 XANTHOSINE (M-H)- Xanthosine 1419 2331 1734 1215 333169 2462 1635 ZEATIN [ISTD] (M+CL)- trans-Zeatin 539032 489449 578330 507903 511685 414301 496262 561462 510134 524727 445901 498481 542977 508488 ZEATIN [ISTD] (M-H)- trans-Zeatin 203536 177578 180137 185701 192657 154352 167204 211061 184460 193986 154376 178567 180255 170644