Metabolite_name RefMet_name ms5952-10 ms5952-11 ms5952-12 ms5952-13 ms5952-14 ms5952-15 ms5952-16 ms5952-27 ms5952-28 ms5952-29 ms5952-30 ms5952-31 ms5952-32 ms5952-33 ms5952-34 ms5952-35 ms5952-36 ms5952-9 ms5952-1 ms5952-17 ms5952-18 ms5952-19 ms5952-2 ms5952-20 ms5952-21 ms5952-22 ms5952-23 ms5952-24 ms5952-25 ms5952-26 ms5952-3 ms5952-4 ms5952-5 ms5952-6 ms5952-7 ms5952-8 Factors - Time point:7 day HS Time point:7 day HS Time point:7 day HS Time point:7 day HS Time point:7 day HS Time point:7 day HS Time point:7 day HS Time point:7 day HS Time point:7 day HS Time point:7 day HS Time point:7 day HS Time point:7 day HS Time point:7 day HS Time point:7 day HS Time point:7 day HS Time point:7 day HS Time point:7 day HS Time point:7 day HS Time point:Control Time point:Control Time point:Control Time point:Control Time point:Control Time point:Control Time point:Control Time point:Control Time point:Control Time point:Control Time point:Control Time point:Control Time point:Control Time point:Control Time point:Control Time point:Control Time point:Control Time point:Control cis-Aconitate cis-Aconitic acid 132.4734 115.4314 121.9559 203.1356 186.3002 171.6320 157.4322 87.6304 92.8376 181.7429 209.0392 122.9852 105.2447 87.9275 122.8048 179.6277 147.5199 105.0137 321.8058 306.2705 232.2791 309.0943 451.7885 270.3313 282.0170 232.2114 292.7943 420.1524 389.4296 274.9334 433.4576 268.6781 560.1572 297.2569 535.8255 667.3994 Citrate Citric acid 438.5632 866.6779 643.6257 969.8509 1482.6776 1484.6236 764.1788 1147.5910 1998.5237 2099.7790 918.4933 867.2343 1668.0079 1017.0932 2301.8337 2824.5452 1976.5938 730.2351 1149.1562 1674.1640 1418.7606 2952.9754 2324.8649 1762.1410 3757.2817 657.5916 2822.0959 3236.2145 3705.0068 1238.3627 1487.2787 644.8027 1485.1318 1065.5453 1887.5293 3590.6412 Fumarate Fumaric acid 4.8206 8.2125 8.2042 20.8693 21.0838 29.3364 9.9494 9.7146 14.4071 31.4341 14.8773 8.1198 14.2363 8.4607 48.1807 51.3914 32.8578 7.3321 24.2436 21.7508 14.6318 43.9204 24.7261 27.4618 20.9756 10.7127 14.2941 53.1361 63.2771 14.8635 19.5456 12.9122 29.9097 15.8710 30.4240 44.3000 Isocitrate Isocitric acid 297.6452 235.4591 265.9326 318.3567 325.4077 385.2771 291.4189 168.0274 179.2232 303.9014 436.2109 244.3747 197.3372 194.9797 192.9299 283.9526 300.7174 220.3776 772.9842 703.1795 545.2759 586.6950 1093.0952 520.9852 593.2775 683.6157 808.5469 965.4617 711.1479 700.0582 1026.4013 631.2193 1149.0391 587.3707 1118.9287 1267.6728 Ketoglutarate 2-Oxoglutaric acid 366.8366 589.6899 576.9798 460.3486 539.5678 894.4680 257.7622 596.2632 858.2226 949.4360 614.5843 463.5759 764.1377 549.1290 860.9199 1056.7565 1179.5451 536.3670 1092.4907 1347.8068 891.6797 1326.7704 1516.9494 841.1916 1272.5428 832.3380 1178.1533 1757.4410 1476.9608 826.8673 1241.3174 783.1997 1021.0630 506.5997 899.2445 1200.6433 Lactate Lactic acid 64.8670 78.2925 79.3189 73.2770 98.5670 138.7821 91.6556 75.4070 105.8832 115.0870 70.5354 71.7662 106.2087 218.4515 69.8211 200.7405 109.4228 58.7345 121.8370 227.8094 217.5317 115.5197 323.9831 86.9142 160.1013 118.5661 243.7257 383.9531 174.6952 126.4500 176.0010 151.5138 161.1560 142.7735 240.7109 448.0035 Malate Malic acid 15.0980 29.1344 28.3837 93.9739 86.8475 124.8918 42.9621 38.1580 62.6348 141.7885 68.1683 30.1553 59.1817 31.8176 225.5199 227.9058 151.8167 27.0719 63.8788 75.1473 47.9427 195.6903 79.9005 129.4884 70.3559 33.0259 50.1049 262.5152 272.8388 57.0379 56.3946 37.2937 130.0189 62.0208 128.4469 194.0166 Oxaloacetate Oxaloacetic acid 0.9100 0.8122 0.7171 0.6984 1.0077 1.1015 1.3463 2.3457 0.5266 0.6300 1.1744 1.5156 0.7713 0.7633 0.9581 0.7300 1.4355 1.7148 0.5094 0.4926 2.2675 1.2680 2.1617 1.8569 2.1284 1.6343 2.7969 1.0759 1.5516 2.0706 6.7716 2.8763 1.3924 1.8068 2.5032 3.3935 Succinate Succinic acid 25.1895 45.1052 33.0179 54.9980 83.5408 87.1460 40.6490 25.2069 41.9399 58.2585 60.3093 30.8164 37.2747 21.8325 108.1776 87.0289 144.0841 27.0376 99.2996 113.4271 69.8159 137.0906 170.0123 97.9518 82.5843 88.4131 82.7877 123.4418 82.0886 47.8759 126.2427 83.0642 142.0350 111.9644 219.4657 272.0322