Metabolite_name RefMet_name GOLPH3_OE_1 GOLPH3_OE_2 GOLPH3_OE_3 GOLPH3_KD_1 GOLPH3_KD_2 GOLPH3_KD_3 LCS_OE_1 LCS_OE_2 LCS_OE_3 LCS_KD_1 LCS_KD_2 LCS_KD_3 CTRL_1 CTRL_2 CTRL_3 Factors - Treatment:GOLPH3 overexpression Treatment:GOLPH3 overexpression Treatment:GOLPH3 overexpression Treatment:GOLPH3 silencing Treatment:GOLPH3 silencing Treatment:GOLPH3 silencing Treatment:LCS overexpression Treatment:LCS overexpression Treatment:LCS overexpression Treatment:LCS silencing Treatment:LCS silencing Treatment:LCS silencing Treatment:no treatment Treatment:no treatment Treatment:no treatment C14-Cer Cer 18:1;O2/14:0 10.1170 10.0990 9.0140 18.4670 18.5600 20.6920 10.1030 9.3770 7.8420 16.0240 14.6850 14.9850 10.5240 12.1430 12.7770 C14HexosylCer HexCer 18:1;O2/14:0 4.2460 4.2260 3.7200 5.9310 6.0100 6.6700 3.5140 3.1960 3.1820 10.5240 9.7750 8.7580 3.1270 3.6220 3.5220 C14Lact-Cer LacCer 18:1;O2/14:0 0.4890 0.4870 0.5510 C14-SM SM 18:1;O2/14:0 119.3930 123.4230 87.9960 158.8790 172.2200 191.9500 120.9920 116.1050 104.6530 131.3380 126.7540 126.7890 125.9890 124.4860 117.3350 C16-Cer Cer 18:1;O2/16:0 28.8330 28.3870 25.9840 53.7580 53.0890 57.0760 29.3870 27.5540 25.1720 75.4110 73.0900 71.3700 35.9060 36.1900 36.6940 C16HexosylCer HexCer 18:1;O2/16:0 110.3250 111.2800 91.7540 132.1450 144.9530 150.3420 81.0720 78.2550 71.2800 443.1440 426.4840 367.8250 75.3480 88.9580 84.5620 C16Lact-Cer LacCer 18:1;O2/16:0 70.0630 67.5400 49.7200 52.2770 55.5320 65.7110 88.3540 86.0980 77.2790 29.6700 27.3310 28.6980 38.1000 43.0910 43.9280 C16-SM SM 18:1;O2/16:0 2273.5390 2314.2360 1671.5770 2541.3050 2998.9930 3180.1840 2238.5470 2270.4500 1948.9840 2953.9940 2961.6020 2761.7610 2189.6300 2160.8570 2171.8850 C18_1-Cer Cer 18:1;O2/18:1 6.6690 6.4750 5.0550 6.5030 7.1850 8.1650 5.8600 5.7680 4.9000 4.5830 4.4100 4.4110 5.2930 6.1520 6.7280 C18_1HexosylCer HexCer 18:1;O2/18:1 1.5540 1.5830 1.4860 1.5890 1.6730 1.6300 1.5000 1.4960 1.5020 1.4470 1.6870 1.5570 1.4350 1.5130 1.5040 C18_1Lact-Cer LacCer 18:1;O2/18:1 0.9220 0.8830 0.8310 1.1510 0.9400 1.0750 1.1570 1.1590 0.9430 0.7030 0.6580 0.7240 0.7360 0.7440 0.8010 C18_1-SM SM 18:1;O2/18:1 65.1870 62.2120 55.0200 60.3360 63.8610 65.4150 62.0460 60.3000 57.5060 50.5760 48.6200 52.1230 60.5930 58.0020 56.0370 C18-Cer Cer 18:1;O2/18:0 15.4930 16.0090 12.5840 17.9530 20.9690 22.1460 15.8950 15.1640 12.7670 18.3910 16.9050 17.2390 13.7980 15.6030 16.2620 C18HexosylCer HexCer 18:1;O2/18:0 10.2520 9.7120 9.7290 10.8380 11.5060 11.0280 8.1360 7.8910 7.6580 36.6490 35.8230 31.0980 7.5310 7.6500 7.7010 C18Lact-Cer LacCer 18:1;O2/18:0 9.4150 9.1860 8.2000 10.6170 9.9660 10.9730 14.1570 13.9640 12.6710 4.9680 4.0750 4.3840 6.0740 7.2360 7.3310 C18-SM SM 18:1;O2/18:0 221.0960 219.2590 190.0590 250.6010 250.2050 272.0890 213.6090 210.5080 208.1440 240.2900 242.5020 235.1960 196.4350 188.5650 187.9460 C20_1-Cer Cer 18:1;O2/20:1 3.5960 3.2000 2.7900 4.7490 4.9170 5.4330 3.4620 2.9350 2.5900 2.5570 2.2230 2.3390 2.6320 2.9990 3.1820 C20_1HexosylCer HexCer 18:1;O2/20:1 2.8370 2.5960 2.4730 4.0950 3.8630 3.8640 2.2840 2.2930 2.1610 3.5290 3.4410 3.1890 1.9940 2.0900 1.9700 C20_1Lact-Cer LacCer 18:1;O2/20:1 1.1450 1.1850 1.1110 1.5340 1.5490 1.5030 1.8130 1.6200 1.6170 0.8450 0.7400 0.7670 1.0630 1.1260 1.0190 C20_1-SM SM 18:1;O2/20:1 30.7440 28.9330 24.7020 39.0040 41.3900 42.9770 28.5160 27.5750 27.7880 20.9930 19.6570 21.1020 26.1750 24.1800 25.3930 C20-Cer Cer 18:1;O2/20:0 13.8200 13.6270 9.9760 18.8950 21.7440 22.6590 14.6490 13.2150 11.9970 16.9460 16.6610 16.8500 9.4820 11.3190 12.6940 C20HexosylCer HexCer 18:1;O2/20:0 7.0900 7.3970 7.1920 7.7630 8.3610 8.0870 5.7710 5.5440 5.4840 18.2920 17.2580 16.1050 5.5210 5.2320 5.3830 C20Lact-Cer LacCer 18:1;O2/20:0 2.7050 2.4720 2.2650 2.7130 2.6570 2.3960 4.0240 4.1100 3.5030 1.4820 1.4030 1.5180 2.0620 2.2080 2.0990 C20-SM SM 18:1;O2/20:0 70.3420 67.9920 52.4910 85.3690 84.1060 96.5040 58.5430 60.6460 59.6180 58.1830 63.3130 57.4610 57.9360 55.9590 52.0210 C22_1-Cer Cer 18:1;O2/22:1 44.3840 42.8030 34.0360 77.1310 84.6480 91.6850 42.9120 41.7570 36.8490 30.9790 30.1980 30.7140 43.4380 46.5630 45.3290 C22_1HexosylCer HexCer 18:1;O2/22:1 23.7200 23.9310 21.8680 41.8870 39.4070 41.3570 17.8820 17.9870 16.9370 31.8120 29.8590 26.6680 13.4940 15.2140 15.4970 C22_1Lact-Cer LacCer 18:1;O2/22:1 7.8950 6.5260 6.7110 10.4190 9.8220 9.8510 13.4910 11.9000 12.1880 3.5280 3.5530 3.6180 6.1270 5.7850 6.1720 C22_1-SM SM 18:1;O2/22:1 379.3790 385.3830 312.1930 521.2900 538.6640 590.0700 346.4050 349.4200 335.2170 210.6570 196.2030 204.9570 364.8910 343.7160 333.9690 C22-Cer Cer 18:1;O2/22:0 80.4180 77.7230 58.1860 121.0180 147.9540 153.8710 81.2740 75.7510 70.8390 102.6730 99.1960 100.8530 62.8670 70.8740 69.5090 C22HexosylCer HexCer 18:1;O2/22:0 223.4500 230.2330 201.5090 293.0050 303.5900 314.5920 178.3980 176.4500 161.9470 485.3360 440.6440 404.0530 162.2350 184.5290 191.0040 C22Lact-Cer LacCer 18:1;O2/22:0 36.4600 34.0820 33.5140 44.8770 44.5960 51.8050 59.2590 57.2790 54.8810 13.0720 13.3590 13.4360 30.9340 34.3470 36.0280 C22-SM SM 18:1;O2/22:0 291.8760 275.1710 240.5300 340.3340 363.9710 402.3250 249.7010 267.3160 241.7770 211.1920 202.9850 209.6540 272.9170 269.6720 268.8820 C24_1-Cer Cer 18:1;O2/24:1 345.4900 347.0290 253.4240 530.9470 588.6720 637.5820 364.0760 341.0590 311.2300 442.1590 444.1610 427.3740 222.9610 254.8540 265.9530 C24_1HexosylCer HexCer 18:1;O2/24:1 705.3670 695.8400 607.6890 878.6200 931.9600 961.1340 584.6630 566.3600 525.6350 1256.1460 1172.3060 1050.3840 454.0740 501.3890 512.0990 C24_1Lact-Cer LacCer 18:1;O2/24:1 148.3760 135.0230 133.2630 177.8860 174.4590 183.7270 243.0610 219.4160 213.9610 56.4900 53.8710 59.0140 105.7500 107.9470 112.6210 C24_1-SM SM 18:1;O2/24:1 2717.1970 2489.5290 2243.3030 3732.9530 3584.0050 3880.4360 2434.5980 2451.2260 2286.4290 2132.0600 2093.1370 2115.0140 2552.0090 2452.5970 2442.8220 C24-Cer Cer 18:1;O2/24:0 135.1230 125.7820 94.7630 155.6770 185.4170 212.3130 124.6160 115.0350 103.9700 143.6100 142.9840 150.3000 95.7210 118.4840 120.5860 C24HexosylCer HexCer 18:1;O2/24:0 369.6300 363.6370 287.9180 445.5790 464.2220 499.8990 281.5780 277.5780 242.5400 724.8270 648.8200 571.0660 253.8480 324.5270 330.9810 C24Lact-Cer LacCer 18:1;O2/24:0 51.8090 48.7470 44.5180 47.9790 47.5910 48.7660 71.8420 69.4860 66.9210 20.7020 19.9950 21.3600 41.1350 43.6460 44.4720 C24-SM SM 18:1;O2/24:0 204.7530 194.9670 189.8210 272.4530 272.5150 283.6150 170.9120 184.2930 157.9750 166.4930 171.6590 164.6540 235.4200 227.6540 237.5270 C26_1-Cer Cer 18:1;O2/26:1 5.0340 4.8170 3.6970 6.4660 8.3300 9.3490 4.7930 4.6970 3.9500 5.1260 5.1670 5.0760 3.1850 3.8340 3.8170 C26_1HexosylCer HexCer 18:1;O2/26:1 23.1890 23.7230 19.6080 32.4330 33.7220 35.2560 18.9920 18.9960 17.5620 35.5020 33.0500 27.5790 20.3960 23.6070 22.5930 C26_1Lact-Cer LacCer 18:1;O2/26:1 5.0150 5.0390 4.5680 5.8490 6.0440 6.0580 6.8220 6.4960 6.4970 3.2810 3.4210 3.3320 4.9420 5.0200 4.6720 C26_1-SM SM 18:1;O2/26:1 14.3270 13.2260 13.1450 28.5710 23.0600 28.4660 11.8250 12.9890 13.0710 11.9870 12.5390 12.8580 17.3320 16.8060 17.8820 C26-Cer Cer 18:1;O2/26:0 1.2120 0.8050 0.5900 0.9720 1.3390 1.3520 0.7730 0.9270 0.7370 0.9650 0.8610 1.3390 0.5190 0.7560 0.7130 C26HexosylCer HexCer 18:1;O2/26:0 4.1330 4.1790 3.7500 4.0760 4.6540 4.8150 3.5430 3.4630 3.5190 4.7230 4.6430 4.7130 3.4790 4.0230 4.0280 C26Lact-Cer LacCer 18:1;O2/26:0 2.3190 2.3070 2.2570 2.3790 2.6240 2.5790 2.4930 2.4890 2.3750 2.0920 2.0940 2.0630 2.1560 2.2820 2.3010 C26-SM SM 18:1;O2/26:0 2.5000 2.2010 2.1830 2.7410 2.7990 2.9180 2.3080 2.2200 2.3190 2.2940 2.3810 2.3670 2.5280 2.4710 2.6230