Metabolite_name RefMet_name FMT1 FMT2 FMT3 FMT4 FMT5 FMT6 FMT7 FMT8 FMT9 FMT10 FMT11 FMT12 FMT13 FMT14 FMT15 FMT16 FMT17 FMT18 Factors - Factor:Control Factor:Control Factor:Control Factor:Control Factor:Control Factor:Control Factor:Control Factor:Control Factor:Control Factor:FMT Factor:FMT Factor:FMT Factor:FMT Factor:FMT Factor:FMT Factor:FMT Factor:FMT Factor:FMT 1_3-Diaminopropane 1,3-Diaminopropane 6.5000 11 1-Methylnicotinamide 1-Methyl nicotinamide 41 19 20 22 23 21 22 7.2000 16 5.1000 2AB 2S-Aminobutyric acid 251 106 126 58 69 79 137 73 110 178 154 144 78 59 80 122 175 129 3-Aminoisobutyrate 3-Aminoisobutanoic acid 129 101 83 50 102 120 138 129 98 84 12 17 3.7000 8.8000 8.9000 10 9.9000 12 3-Aminopropane-1_2-diol (S)-3-Amino-1,2-propanediol 51 23 30 32 35 31 54 25 46 37 47 35 14 11 9.2000 20 21 18 3-Hydroxyanthranilate 3-Hydroxyanthranilic acid 30 9.8000 18 146 18 24 18 13 75 17 20 3-Methylhistidine 3-Methylhistidine 11 6.5000 7.8000 6.2000 7.9000 7.3000 8.1000 5.8000 6.9000 9.7000 9.6000 8.6000 5.1000 3 3.7000 6.1000 5.8000 10 4-(beta-Acetylaminoethyl)imidazole N-Acetylhistamine 16 11 9.8000 3.8000 4 3.1000 6.1000 5.3000 5 5.6000 5.9000 4.3000 8.1000 6.2000 13 9.1000 11 9.4000 4-Hydroxymethylimidazole Imidazole-4-methanol 8 5.4000 4.2000 6.2000 5.4000 6.4000 7.2000 5.6000 8.4000 6.7000 7.1000 7.9000 8.6000 6.9000 10 5.5000 9.3000 6.8000 5-Aminolevulinate 5-Amino-levulinic acid 10 8.1000 8.7000 7.3000 20 13 14 16 11 10 9.6000 9.1000 13 10 15 12 5-Aminovalerate 5-Aminopentanoic acid 51201 3885 31871 6825 9425 16397 7395 11899 8969 3189 2223 3857 8464 7080 571 6819 7601 7163 5-Hydroxyindoleacetate 5-Hydroxyindoleacetic acid 1510 1232 1316 826 912 849 820 825 908 1205 923 990 752 710 955 767 864 700 5-Hydroxylysine 5-Hydroxylysine 144 75 77 72 81 73 88 55 82 80 152 89 5.8000 35 14 7.5000 8.9000 9.8000 5-Methylthioadenosine 5'-Methylthioadenosine 13 6.2000 5.6000 12 9.2000 8 17 9.6000 13 21 29 29 4.9000 5.5000 5.8000 5.3000 7.6000 6.2000 6-Aminohexanoate Aminocaproic acid 11 8.2000 5.5000 19 6.3000 23 11 6-Hydroxynicotinate 6-Hydroxynicotinic acid 55 33 31 51 48 26 61 32 51 7-Methylguanine 7-Methylguanine 27 15 21 18 26 22 22 17 23 19 14 14 Adenine Adenine 4.3000 4 8 4.8000 4.7000 3.6000 6 7.6000 6.1000 6 5.3000 4.9000 3.8000 4.4000 5.5000 6.5000 7.8000 Adenosine Adenosine 19 9.5000 15 21 19 15 22 11 15 23 15 18 10 10 9 7.1000 7.4000 16 ADMA Dimethylarginine 43 21 23 18 22 19 34 11 24 34 35 25 14 15 12 11 11 15 Agmatine Agmatine 13 5.9000 7 3.8000 4.2000 4.5000 12 4.8000 9.1000 6.5000 7.6000 7.8000 2.7000 2.3000 3.1000 2.8000 4 3.8000 Ala Alanine 2847 1300 1690 932 907 1150 2388 1340 1723 954 932 854 447 413 457 746 818 956 Ala-Ala Ala-Ala 648 203 336 261 206 228 499 153 363 191 195 164 84 48 73 112 149 179 Allantoin Allantoin 200 166 137 223 145 216 294 199 494 156 63 15 131 86 100 127 133 572 alpha-Aminoadipate Aminoadipic acid 31 24 28 28 27 26 35 31 36 31 32 24 27 21 19 20 25 27 Alpha-Methylserine Alpha-Methylserine 16 9.8000 10 9.5000 6.2000 11 33 14 26 16 13 17 11 12 9.8000 15 Arg Arginine 1578 436 779 428 444 327 947 301 708 542 833 529 219 213 206 306 378 426 Asn Asparagine 936 357 566 141 209 213 723 249 527 51 227 70 106 125 118 134 136 134 Asp Aspartic acid 2487 1070 1257 975 1267 1134 2209 992 1586 923 1276 812 312 463 495 417 491 651 beta-Ala beta-Alanine 231 46 53 50 41 39 144 30 72 150 88 69 35 29 31 32 37 48 beta-Imidazolelactate Imidazolelactic acid 59 37 22 42 43 70 55 74 64 67 65 Betaine Betaine 40 40 65 74 96 94 86 102 64 131 150 122 67 98 65 31 50 60 Betonicine Betonicine 15 6.5000 12 Cadaverine Cadaverine 31 18 24 9.7000 12 13 16 11 16 21 19 16 14 12 21 15 19 15 Carnitine Carnitine 22 22 14 21 26 19 45 16 27 75 101 61 45 39 48 35 48 59 Choline Choline 116 120 91 96 108 117 135 139 130 98 56 72 85 94 103 73 90 101 Citrulline Citrulline 70 62 38 57 56 62 47 48 53 279 86 226 58 67 56 99 77 201 Creatine Creatine 18 27 9.8000 16 15 30 30 97 15 14 6.9000 11 77 675 51 48 32 461 Creatinine Creatinine 8.7000 7 13 9.4000 9.4000 11 9.8000 23 11 8.7000 8.1000 9.5000 13 18 15 15 14 31 Cyclohexylamine Cyclohexylamine 2.5000 2.2000 3 2.7000 Cytidine Cytidine 11 12 10 8.9000 25 11 23 Cytosine Cytosine 21 15 20 6.1000 5.4000 5.2000 4.9000 Diethanolamine Diethanolamine 49 13 32 5.3000 29 19 22 124 68 61 75 37 63 3 12 44 8.4000 26 Ectoine Ectoine 5.3000 4.2000 4.3000 3.6000 5.3000 4.5000 5.8000 5.8000 6.4000 5.2000 4.2000 5 4 3 3.5000 3.7000 3.5000 3.8000 GABA gamma-Aminobutyric acid 112 92 78 43 65 64 75 160 84 77 36 94 56 56 44 100 95 73 gamma-Butyrobetaine 3-Dehydroxycarnitine 324 133 210 154 136 159 217 85 161 201 291 266 90 77 76 118 149 128 gamma-Glu-2AB gamma-Glutamyl-2-aminobutanoate 154 96 97 111 134 99 139 89 150 gamma-Guanidinobutyrate 4-Guanidinobutanoic acid 28 25 24 14 22 24 22 61 28 6.1000 4.8000 6.4000 8.6000 6.7000 9.2000 8.8000 9.8000 12 Gln Glutamine 828 438 580 334 384 479 448 281 440 320 339 320 223 195 214 218 265 458 Glu Glutamic acid 34744 22198 15983 15128 18105 16346 22498 13800 20363 11529 10589 9333 4334 4472 4165 5504 6567 10481 Glucosaminate Glucosaminic acid 15 9.2000 15 8 9.1000 5.7000 9.8000 12 Glucosamine Glucosamine 56 52 58 67 68 70 69 33 39 37 34 36 26 Gly Glycine 821 533 745 691 771 854 1288 775 1044 638 903 585 488 557 409 352 365 707 Glycerophosphorylcholine sn-Glycero-3-phosphocholine 40 56 29 36 34 32 35 32 Gly-Gly Gly-Gly 26 23 24 22 24 29 25 23 24 20 21 14 15 15 11 13 8.9000 15 Gly-Leu Gly-Leu 57 38 42 48 53 44 64 47 56 39 35 36 29 39 30 25 26 38 Guanidinoacetate Guanidoacetic acid 6.5000 4.5000 2.8000 2.9000 4.9000 5.9000 8.7000 3.9000 3.1000 8.1000 3.8000 13 Guanidinosuccinate Guanidinosuccinic acid 10 12 11 Guanine Guanine 51 49 55 48 61 56 70 86 82 45 44 51 88 90 102 67 83 76 Guanosine Guanosine 28 17 His Histidine 331 108 196 140 157 129 257 106 218 211 322 206 111 97 108 117 148 140 Histamine Histamine 22 14 17 6.9000 7.4000 5.8000 12 7.4000 13 8.6000 11 8.2000 12 7.9000 15 11 8.9000 10 Homoserine Homoserine 53 61 52 32 39 41 39 29 44 39 32 40 40 29 39 30 39 30 Homovanillate Homovanillic acid 96 73 28 41 39 22 131 131 130 93 29 88 Hydroxyproline Hydroxyproline 123 55 82 313 435 507 802 1617 990 193 196 162 113 111 38 49 49 57 Hypoxanthine Hypoxanthine 9.8000 7.9000 9 24 28 23 10 8.2000 11 75 19 54 10 11 7.4000 5.7000 8.9000 16 Ile Isoleucine 167 99 96 43 58 78 111 73 89 63 60 71 40 61 59 89 120 300 Indole-3-acetaldehyde Indoleacetaldehyde 904 625 755 748 723 713 967 923 1068 686 724 676 566 426 581 620 551 636 Indole-3-acetamide 1H-Indole-3-acetamide 103 85 89 61 80 77 71 98 105 64 91 61 47 46 56 77 62 70 Inosine Inosine 45 13 21 92 140 125 55 428 231 420 19 21 18 36 Isopropanolamine Isopropanolamine 252 35 72 80 71 49 134 27 103 15 21 117 8.6000 Leu Leucine 432 308 234 89 103 134 207 146 143 140 125 149 93 117 114 207 249 691 Lys Lysine 5109 1774 2282 2259 2313 2033 3388 1565 2884 3081 3463 3141 1456 1330 1415 1556 2061 2117 Mannosamine 2-Amino-2-deoxy-D-mannose 92 57 88 74 83 69 138 85 100 Met Methionine 257 152 160 114 137 146 212 116 157 174 135 147 65 70 71 105 113 187 Methionine sulfoxide Methionine sulfoxide 61 67 83 54 74 75 71 81 89 59 33 71 75 73 82 89 112 165 N1-Acetylspermidine N1-Acetylspermidine 180 74 121 71 57 79 114 24 72 80 174 55 20 12 16 57 25 27 N1_N12-Diacetylspermine N1,N12-Diacetylspermine 4.8000 1.5000 3.4000 1.7000 1.7000 2.8000 0.9600 1 1.6000 1.7000 1.5000 N1_N8-Diacetylspermidine N1,N8-Diacetylspermidine 143 43 72 53 57 49 61 30 58 52 8.8000 11 6.5000 5.6000 5.9000 100 61 82 N6_N6_N6-Trimethyllysine N-6-Trimethyllysine 19 7 10 8.6000 9.9000 10 15 9.5000 14 19 16 18 35 14 11 55 12 55 N8-Acetylspermidine N8-Acetylspermidine 22 5.5000 14 11 8.6000 11 13 4.7000 8.6000 7.6000 5.8000 2.2000 2.4000 2.7000 9.8000 3.9000 4.3000 N-Acetylglucosamine N-Acetyl-D-glucosamine 184 95 118 138 84 147 132 N-Acetylglucosylamine N-Acetyl-beta-glucosaminylamine 72 N-Acetylornithine N-Acetylornithine 31 15 21 17 16 19 23 16 22 19 17 17 12 10 7.2000 10 14 15 N-Acetylputrescine N-Acetylputrescine 240 97 133 163 204 184 284 194 234 475 71 172 59 36 32 29 43 91 N-epsilon-Acetyllysine N6-Acetyllysine 48 25 22 23 26 24 36 19 33 28 30 28 15 14 19 15 20 18 Nicotinamide Niacinamide 63 35 41 55 46 43 63 43 52 102 71 100 53 48 58 40 64 61 N-Methylalanine N-Methylalanine 6.1000 5.9000 5.6000 8 5.6000 6.3000 o-Acetylcarnitine CAR 2:0 2.1000 4 O-Acetylserine O-Acetylserine 43 15 25 15 10 20 16 Ophthalmate Ophthalmic acid 77 33 52 65 76 61 84 57 71 Ornithine Ornithine 342 339 145 83 95 149 161 147 147 117 135 107 65 76 73 88 103 151 p-Aminobenzoate p-Aminobenzoic acid 5.9000 6.5000 Phe Phenylalanine 179 85 100 47 63 64 118 64 86 60 56 69 41 73 51 65 85 163 Phosphorylcholine Choline phosphate 127 80 56 142 144 87 182 86 89 126 76 69 27 18 29 34 28 Pipecolate Pipecolic acid 80 42 52 44 59 51 73 69 72 71 47 81 51 62 69 64 66 72 Pro Proline 1979 701 1135 1840 3134 2201 3861 6095 3644 1853 1759 1712 824 654 417 669 723 844 Putrescine(1_4-Butanediamine) Putrescine 59 33 43 25 27 34 40 19 39 76 43 42 17 19 25 22 17 28 Pyridoxal Pyridoxal 23 15 15 8.8000 12 13 15 13 16 17 10 17 16 14 15 13 16 14 Pyridoxamine Pyridoxamine 2.7000 3.2000 Pyridoxamine 5^-phosphate Pyridoxamine 5'-phosphate 22 8.9000 11 21 11 17 12 Saccharopine Saccharopine 26 15 19 33 40 38 36 27 47 13 12 SAM+ S-Adenosylmethionine 48 17 21 32 24 23 58 22 39 45 88 73 11 8.5000 10 9.5000 11 13 Sarcosine Sarcosine 66 65 63 70 66 103 82 91 66 112 139 97 125 152 53 67 58 103 SDMA Symmetric dimethylarginine 23 11 12 14 14 13 14 11 16 22 21 19 9.8000 8.3000 11 9.4000 11 11 Ser Serine 718 403 449 482 562 596 831 550 765 678 395 528 351 373 335 259 297 554 Serotonin Serotonin 12 12 14 9.7000 10 12 14 16 19 9.9000 8.8000 11 17 12 11 Spermidine Spermidine 385 68 138 70 68 82 156 32 122 183 130 120 29 28 41 40 33 39 Synephrine Synephrine 26 Taurine Taurine 1458 999 878 1025 1466 3007 963 2034 1096 1719 1289 2414 214 2084 107 119 88 190 Thiamine Thiamine 9.7000 6.2000 8.5000 12 11 12 7.6000 12 20 17 21 13 18 34 43 39 31 Thr Threonine 433 212 279 262 299 273 550 200 389 316 474 300 114 137 131 112 160 226 Thymidine Thymidine 114 79 89 77 74 58 110 86 84 101 107 56 78 82 78 Thymine Thymine 120 122 114 168 150 173 154 158 153 175 137 163 101 115 109 114 104 124 Trigonelline Trigonelline 4.8000 5.9000 4.3000 2.8000 4.3000 5.5000 5.1000 11 3.9000 9.8000 Trp Tryptophan 136 47 59 60 69 59 127 34 91 87 84 92 29 38 34 37 56 63 Tryptamine Tryptamine 4.4000 5.6000 3.6000 4.6000 Tyr Tyrosine 520 156 226 142 176 148 415 122 248 193 225 276 63 105 87 155 212 289 Tyramine Tyramine 34 25 20 11 12 14 8.8000 6.9000 15 16 13 11 7.4000 5.4000 9.1000 5.9000 5.2000 12 Uracil Uracil 55 58 Urea Urea 58 40 42 34 Uridine Uridine 336 115 108 131 138 119 294 269 282 386 193 258 103 74 112 94 87 113 Urocanate Urocanic acid 23 13 12 20 18 15 16 9.1000 11 35 16 32 9.1000 8.7000 7.6000 5.1000 7.8000 23 Val Valine 572 373 275 146 177 229 354 265 291 283 200 225 182 219 209 339 381 931 Xanthine Xanthine 224 167 Xanthurenate Xanthurenic acid 9