metabolite_name CNS_HILIC_NEG_WT_1 CNS_HILIC_NEG_WT_2 CNS_HILIC_NEG_WT_3 CNS_HILIC_NEG_WT_4 CNS_HILIC_NEG_WT_5 CNS_HILIC_NEG_ifc_1 CNS_HILIC_NEG_ifc_2 CNS_HILIC_NEG_ifc_3 CNS_HILIC_NEG_ifc_4 CNS_HILIC_NEG_ifc_5 Glucose 74696 179970 207611 142268 110533 285615 334420 199017 405114 460725 Glucose-6-phosphate 10462747 8898463 7817362 5608536 3319351 8926097 5340995 6592602 3839139 11148568 Fructose-bisphosphate 4769995 3639578 3524429 1766953 1181870 1829980 1201933 2593294 913269 2745753 DHAP 3668858 3187430 2541948 2480262 1786925 2512405 1582788 1876758 863240 2856584 2/3-PG 10117220 7404940 7975729 8637683 4896285 7776982 4580916 6725154 2229932 7389270 Phosphoenolpyruvate 1350545 1256355 1105873 2056861 1057636 1867847 819847 1066770 456797 1155046 Pyruvate 6781792 6853737 7733112 7753924 4939750 5194759 2186314 3108875 2199156 4470578 Lactate 163367072 162557424 178863696 162612688 55214372 142212080 116097240 123674496 108373640 220292624 Ribose-5-phosphate 279939 222457 238256 248302 116767 178134 115994 89377 46108 230322 Xylulose-5-phosphate 1002874 751677 632660 584617 294921 173909 164733 249856 128977 272931 Sedoheptulose 7-phosphate 701029 516959 455236 374832 225028 666551 392189 479461 322631 730300 Citrate 14376626 10081685 12763893 11270391 8440789 8679889 7003505 11779377 6850207 7893539 Aconitate 432687 305538 412199 459274 232611 224623 182380 146754 148847 244208 a-KG 3552646 3217245 6002153 4809215 4451411 1581942 1938666 517468 2804987 535148 Succinate 4849468 4398069 5584810 4453286 3717677 3404759 3040595 2728796 3745989 3313411 Fumarate 4968113 3882456 4069848 4220959 2453214 1482555 1152324 980629 1287951 1145254 Malate 92474904 74137832 78688448 79680816 51784788 31037792 27295614 22730766 32364764 27176226 Glutamate 72897584 61447276 62316960 62789948 38095816 29617358 24109804 20739730 20510334 31097440 Glutamine 9216221 8321454 9242683 4714363 3387664 9234541 7893601 8010228 5861898 11096252 Aspartate 18008528 15506260 13777500 17244506 9513131 9826667 8109509 10005007 9324621 10619394 Alanine 18446084 16033727 16917788 17420428 11125637 10984710 9291824 8230299 9420786 12983297 Glycine 3459788 2995372 2913461 2960821 2244183 3135420 2482299 1827466 2461698 2770863 Valine 6420958 4918644 5305802 4611946 3072850 4301667 3218734 3148612 3093621 4647418 Leucine 12869739 10067751 11021671 10085213 6430167 9617550 7535678 6468857 6041789 9452037 Isoleucine 5630789 4578674 4218202 4046444 2523233 3752941 3160560 3698076 2820690 4142319 Asparagine 7054756 4947224 5668789 4609133 3099465 4413688 3626815 3726911 3313147 4281615 Proline 14182377 12749668 12712447 10434846 7056130 8217975 7168406 6767594 5561083 8467954 Histidine 55436208 38472448 45683116 37391596 29732840 53078336 41413600 36548380 42731448 44402500 Methionine 400898 423117 379857 652420 330819 340875 273561 271239 221745 506647 Lysine 177161 152771 177257 139709 115717 184762 152845 222214 155389 147254 Arginine 9149549 7235640 7771671 6510176 4164172 9306020 7276095 14209337 5497869 9729785 Phenylalanine 10905424 7887443 8643994 7332766 5210003 8391279 6082753 5203893 5135778 6556145 Serine 5366600 3876879 4350332 3517178 2631896 3904262 2791387 2904754 2611120 3365434 Threonine 4532314 3588058 4405262 3965794 2751471 3291358 2383681 2060625 2410975 3057937 Tyrosine 9175983 7685924 7635100 8866497 5547080 4406173 4348334 3494135 3181079 5037070 Glycerol 3-phosphate 14228118 11544128 9501583 14799665 7757904 9946407 6767875 6576690 3850885 10728683 Adenine 2170599 2590831 2763518 3583098 1206636 2887727 1983672 1325210 1357729 2739640 Uracil 8391266 7621532 7108142 7973626 4529043 2567129 1838600 1989940 1384695 3192395 Guanosine 133224 187694 83392 191482 30966 100744 103260 59037 69043 207606 Uridine 3084498 2151790 2006214 1173855 645614 559785 509376 548705 433362 1173459 Cytidine 1624881 1594032 1159073 1900164 632334 336928 256765 291163 231967 549292 Glutathione, reduced 30069660 22450640 21579182 27472310 15412513 20214324 16281416 17832258 9530146 21706466 Glutathione, oxidized 64590 76752 55044 127622 46612 51800 55089 179256 70863 66812 UMP 246253 292916 184313 244008 86083 304412 218946 261125 175675 302227 UDP 222518 250796 149220 143697 100402 166153 128919 160560 124556 220495 UTP 64437 24777 30141 8428 18962 27457 15570 40140 8716 31633 AMP 11928166 12923707 8011402 12620946 4089593 9456784 7538137 6868374 5057153 11322906 ADP 6917115 5697804 3918895 5352337 2158835 3667045 3446770 3551350 2604289 4244692 ATP 1614866 961505 990525 509732 557205 477663 504099 994607 357856 554265 NAD+ 2270037 1874030 1763841 1965699 932544 2117275 1777953 1454061 1170756 2235945 NADH 1196812 569495 539429 342399 211488 572599 392534 475828 179454 769694 NADP+ 26965 25502 6638 11508 2899 14760 15160 37266 17483 21961 CMP 109463 144018 62337 136551 38194 77652 64613 52812 36873 81030 CDP 186815 184676 116134 124079 68092 76406 76248 104435 48414 92743 CDP-Choline 176103 125598 144142 80872 61232 64836 52087 65766 33865 72626 FAD 605012 560628 514977 488946 200263 581107 414942 493082 233052 646078 GMP 862530 824882 420832 786439 261324 377160 324169 330604 251194 525127 GDP 268130 299310 221860 183622 132200 154427 156973 163766 135279 189150 dGTP 1616778 963589 992979 509732 560080 477670 504107 994592 358254 554273 UDP-glucose / UDP-galatose 1940225 1432762 1352815 1140533 713504 1055090 747804 1009512 553516 1376280 Uridine 5'-diphosphoglucuronic acid 52738 47016 39415 36466 12228 46113 37799 131237 24483 51081 UDP-N-acetylglucosamine 2769260 2043535 2080915 1873956 1112215 1469386 1258949 1477529 889110 2091926 Glucosamine-6-phosphate 891093 558200 606170 588668 391188 917027 935100 630629 674126 1147025 GlcNAc-Phosphate 257271 195743 191753 194855 108367 203878 191827 189138 110732 253865 S-Adenosylhomocysteine 447524 267359 230862 441766 187489 213612 152797 202847 103845 234831 S-Adenosylmethionine 1307916 962768 958909 858074 579742 649950 526820 505056 299540 706814 Carnitine 174012832 124040536 109210808 105368328 58189568 74499152 64668264 78192656 55985516 95213608 3-Indoleacrylic acid 49177744 34631228 37051248 32638162 25186510 43740824 34041252 30559054 28708754 38940256 Acetyl-Lysine 140550 376874 613263 668033 93733 715909 443792 221807 349601 584344 N,N-Dimethylarginine 386399 359457 284960 339507 128340 318945 243109 112698 127301 410753 Acetylcarnitine 270554848 215202432 240633424 217319808 132356800 185426928 152079488 135105520 85816520 192298144 Glu-gln 1994686 1650913 1945404 1722750 1035031 901941 735006 849137 378636 975247 Methyladenosine 271705 254633 223983 217357 134891 185874 117470 102463 48366 221683 Cysteine-glutathione disulfide 277717 245956 319839 418672 88807 180520 176579 272320 189422 219541 2KIVA 1032692 1013943 1034906 1010798 642026 947922 517305 2127795 890938 533158 metabolite_name Glucose Glucose-6-phosphate Fructose-bisphosphate DHAP 2/3-PG Phosphoenolpyruvate Pyruvate Lactate Ribose-5-phosphate Xylulose-5-phosphate Sedoheptulose 7-phosphate Citrate Aconitate a-KG Succinate Fumarate Malate Glutamate Glutamine Aspartate Alanine Glycine Valine Leucine Isoleucine Asparagine Proline Histidine Methionine Lysine Arginine Phenylalanine Serine Threonine Tyrosine Glycerol 3-phosphate Adenine Uracil Guanosine Uridine Cytidine Glutathione, reduced Glutathione, oxidized UMP UDP UTP AMP ADP ATP NAD+ NADH NADP+ CMP CDP CDP-Choline FAD GMP GDP dGTP UDP-glucose / UDP-galatose Uridine 5'-diphosphoglucuronic acid UDP-N-acetylglucosamine Glucosamine-6-phosphate GlcNAc-Phosphate S-Adenosylhomocysteine S-Adenosylmethionine Carnitine 3-Indoleacrylic acid Acetyl-Lysine N,N-Dimethylarginine Acetylcarnitine Glu-gln Methyladenosine Cysteine-glutathione disulfide 2KIVA