{
"METABOLOMICS WORKBENCH":{"STUDY_ID":"ST000095","ANALYSIS_ID":"AN000151","VERSION":"1","CREATED_ON":"2016-09-17"},

"PROJECT":{"PROJECT_TITLE":"Dysfunctional lipid metabolism underlies the effect of perinatal DDT exposure the development of metabolic syndrome","PROJECT_TYPE":"Animal chemical exposure and feeding study","PROJECT_SUMMARY":"This study evaluated the effect of perinatal DDT exposure on metabolic syndrome mice exposed to doses that mimicked human exposure. The samples tested were 2 groups: 1) a group with perinatal exposure to DDT consuming a high fat diet 2) a control group consuming a high fat diet (CHF). Results indicated the DDHF had comparatively elevated plasma concentrations of glucose, insulin, and triglycerides, CYP7A1 gene expression, homeostasis model assessment- resistance (HOMA-IR), and fat mass (%), as well as reduced thermogenesis. These suggest perinatal DDT exposure may cause the co-occurrence of conditions with metabolic syndrome, including glucose intolerance, hyperinsulinemia, and impaired thermogenesis, and obesity.","INSTITUTE":"University of California, Davis","DEPARTMENT":"Environmental Toxicology","LABORATORY":"La Merrill","LAST_NAME":"La Merrill","FIRST_NAME":"Michele","ADDRESS":"1 Shields Ave, Davis CA","EMAIL":"mlamerrill@ucdavis.edu","PHONE":"+1-530-754-7254","FUNDING_SOURCE":"National Institute of Health (R00 ES019919, R03 DK082724, U24 DK092993, U24 T32 ES007059, and P60 DK020541), the American Diabetes Association, and intramural Project 5306-51530-019-00D"},

"STUDY":{"STUDY_TITLE":"Dysfunctional lipid metabolism underlies the effect of perinatal DDT exposure the development of metabolic syndrome","STUDY_TYPE":"Chemical dosage and feeding study","STUDY_SUMMARY":"Targeted metabolomic analysis of bile acids was performed on 15 mouse liver collected from mice euthanized at 9 months following consumption of a high fat w/o perinatal DDT exposure. Funded by the National Institute of Health (R00 R03 DK082724, U24 DK092993, U24 DK097154, T32 ES007059, and P60 DK020541), the Diabetes Association, and USDA-ARS intramural Project 5306-51530-019-00D. were analyzed by UPLC-MS/MS using a Waters Acquity UPLC and detected on an API QTrap (AB Sciex, Framingham, MA, USA) by multiple reaction monitoring (MRM) negative mode electrospray ionization.","INSTITUTE":"University of California, Davis","DEPARTMENT":"U.S.D.A. Western Human Nutrition Research Center","LABORATORY":"Newman","LAST_NAME":"John","FIRST_NAME":"Newman","ADDRESS":"430 W. Health Sciences Dr., Davis, CA 95616","EMAIL":"john.newman@ars.usda.gov","PHONE":"+1-530-752-1009","NUM_GROUPS":"2","TOTAL_SUBJECTS":"15"},

"SUBJECT":{"SUBJECT_TYPE":"Animal","SUBJECT_SPECIES":"Mus musculus","TAXONOMY_ID":"10090","AGE_OR_AGE_RANGE":"9 months","GENDER":"Female","ANIMAL_HOUSING":"Singly housed","ANIMAL_FEED":"High fat diet (HFD, 4.73 kcal/g, 20% protein, 35% carbohydrate, and 45% fat per D12451, Research Diets, New Brunswick, NJ)","SPECIES_GROUP":"Mammal"},
"SUBJECT_SAMPLE_FACTORS":[
{
"Subject ID":"-",
"Sample ID":"T12-4",
"Factors":{"Treatment":"DDT"}
},
{
"Subject ID":"-",
"Sample ID":"T18-3",
"Factors":{"Treatment":"DDT"}
},
{
"Subject ID":"-",
"Sample ID":"T26-6",
"Factors":{"Treatment":"DDT"}
},
{
"Subject ID":"-",
"Sample ID":"T30-2",
"Factors":{"Treatment":"DDT"}
},
{
"Subject ID":"-",
"Sample ID":"T31-6",
"Factors":{"Treatment":"DDT"}
},
{
"Subject ID":"-",
"Sample ID":"T36-4",
"Factors":{"Treatment":"DDT"}
},
{
"Subject ID":"-",
"Sample ID":"T43-1",
"Factors":{"Treatment":"DDT"}
},
{
"Subject ID":"-",
"Sample ID":"T52-6",
"Factors":{"Treatment":"DDT"}
},
{
"Subject ID":"-",
"Sample ID":"V32-6",
"Factors":{"Treatment":"OIL"}
},
{
"Subject ID":"-",
"Sample ID":"V38-9",
"Factors":{"Treatment":"OIL"}
},
{
"Subject ID":"-",
"Sample ID":"V44-2",
"Factors":{"Treatment":"OIL"}
},
{
"Subject ID":"-",
"Sample ID":"V47-6",
"Factors":{"Treatment":"OIL"}
},
{
"Subject ID":"-",
"Sample ID":"V69-3",
"Factors":{"Treatment":"OIL"}
},
{
"Subject ID":"-",
"Sample ID":"V77-5",
"Factors":{"Treatment":"OIL"}
},
{
"Subject ID":"-",
"Sample ID":"V78-6",
"Factors":{"Treatment":"OIL"}
}
],
"COLLECTION":{"COLLECTION_SUMMARY":"-","COLLECTION_PROTOCOL_FILENAME":"Newman_Lab_Bile_Acids_Extraction_&_Analysis_Protocol_La_Merrill_WCMC_P&F.pdf","SAMPLE_TYPE":"Liver tissue","COLLECTION_METHOD":"Dissection","STORAGE_CONDITIONS":"- 80°C","STORAGE_VIALS":"Eppendorf tubes"},

"TREATMENT":{"TREATMENT_SUMMARY":"1.7 mg DDT/kg body weight was administered to dams daily on gestational day 11 postnatal day 5 and litters were culled to 6 mice at postnatal day 6. Mice were screened from 2-6 months when they consumed a high fat diet. Mice were at 9 months of age.","TREATMENT_PROTOCOL_FILENAME":"Newman_Lab_Bile_Acid_Protocols_La_Merrill_WCMC_P&F.pdf","TREATMENT":"Intervention","TREATMENT_COMPOUND":"p,p`-DDT, o,p`-DDT","TREATMENT_ROUTE":"Oral","TREATMENT_DOSE":"77.2% p,p`-DDT (98.5% purity neat, AccuStandard, New Haven, CT) and 22.8% (100% purity neat, AccuStandard) were dissolved at a final concentration of g DDT mixture/L organic olive oil","TREATMENT_DOSEDURATION":"From 11.5 days post coitus to postnatal day 5","TREATMENT_VEHICLE":"Olive oil","ANIMAL_ENDP_EUTHANASIA":"9 months","ANIMAL_ENDP_TISSUE_COLL_LIST":"Liver"},

"SAMPLEPREP":{"SAMPLEPREP_SUMMARY":"A 15 mg liver sample (n=1 female/litter in 7 VEH and 8 DDT litters) was on dry ice, enriched with deuterated bile acid surrogates, butylated and ethylinediaminetetraacetic acid, and extracted twice with 500 uL methanol. combined extract was dried, reconstituted in 100uL 50:50 methanol:acetonitrile internal standards 1-phenyl-3-hexanoic acid urea and 1-cyclohexyl-3-dodecanoic urea (Sigma-Aldrich, St. Louis, MO) and filtered at 0.1 µm.","SAMPLEPREP_PROTOCOL_FILENAME":"Newman_Lab_Bile_Acid_Protocols_La_Merrill_WCMC_P&F.pdf","PROCESSING_METHOD":"Pulverization on dry ice","EXTRACTION_METHOD":"Methanol","EXTRACT_STORAGE":"Placed in 10 °C autosampler and immediately analyzed","SAMPLE_SPIKING":"Spiked with deuterated bile acid surrogates.","ORGAN":"Liver"},

"CHROMATOGRAPHY":{"CHROMATOGRAPHY_SUMMARY":"Targeted UPLC-MS/MS method","CHROMATOGRAPHY_TYPE":"Reversed phase","INSTRUMENT_NAME":"Waters Acquity UPLC detector","COLUMN_NAME":"Waters Acquity BEH C18 (100 x 2mm, 1.7um)","METHODS_FILENAME":"Newman_Lab_Bile_Acids_Extraction_&_Analysis_Protocol_La_Merrill_WCMC_P&F.pdf","COLUMN_TEMPERATURE":"60 C","FLOW_GRADIENT":"Yes","FLOW_RATE":"0.4mL/min","INTERNAL_STANDARD":"See protocol/methods file","SAMPLE_INJECTION":"5 L","SOLVENT_A":"0.1% formic acid","SOLVENT_B":"0.1% formic acid in acetonitrile","ANALYTICAL_TIME":"16 min","WEAK_WASH_SOLVENT_NAME":"20% methanol, 10% isopropanol","WEAK_WASH_VOLUME":"600 L","STRONG_WASH_SOLVENT_NAME":"50:50 Acetonitrile:Methanol","STRONG_WASH_VOLUME":"600 L","SAMPLE_LOOP_SIZE":"17 L"},

"ANALYSIS":{"ANALYSIS_TYPE":"MS","LABORATORY_NAME":"Newman","ACQUISITION_DATE":"41703","SOFTWARE_VERSION":"AB Sciex Analyst version 1.6.2","OPERATOR_NAME":"Michael La Frano","DETECTOR_TYPE":"API 4000 QTrap (AB Sciex, Framingham, MA, USA)","DATA_FORMAT":".mzML"},

"MS":{"MS_COMMENTS":"-","INSTRUMENT_NAME":"ABI Sciex API 6500 QTrap","INSTRUMENT_TYPE":"Triple quadrupole","MS_TYPE":"ESI","ION_MODE":"NEGATIVE","ION_SOURCE_TEMPERATURE":"See protocol/methods file","ION_SPRAY_VOLTAGE":"See protocol/methods file"},

"MS_METABOLITE_DATA":{
"Units":"% abundance",

"Data":[{"Metabolite":"Chenodeoxycholic acid","T12-4":"0.0584","T18-3":"","T26-6":"0.1920","T30-2":"0.1520","T31-6":"0.1060","T36-4":"0.0338","T43-1":"0.2120","T52-6":"","V32-6":"","V38-9":"","V44-2":"","V47-6":"","V69-3":"","V77-5":"","V78-6":""},{"Metabolite":"Cholic acid","T12-4":"236.0000","T18-3":"104.0000","T26-6":"89.8000","T30-2":"99.5000","T31-6":"78.0000","T36-4":"41.9000","T43-1":"500.0000","T52-6":"","V32-6":"","V38-9":"","V44-2":"","V47-6":"","V69-3":"","V77-5":"","V78-6":""},{"Metabolite":"Deoxycholic acid","T12-4":"0.3500","T18-3":"0.2960","T26-6":"0.7480","T30-2":"0.2020","T31-6":"0.5030","T36-4":"0.0612","T43-1":"1.5300","T52-6":"","V32-6":"","V38-9":"","V44-2":"","V47-6":"","V69-3":"","V77-5":"","V78-6":""},{"Metabolite":"Dihydroxycholestanoic acid","T12-4":"0.8338","T18-3":"0.5174","T26-6":"0.6836","T30-2":"0.6139","T31-6":"0.5282","T36-4":"0.0579","T43-1":"0.8606","T52-6":"","V32-6":"","V38-9":"","V44-2":"","V47-6":"","V69-3":"","V77-5":"","V78-6":""},{"Metabolite":"Glychochenodeoxycholic acid","T12-4":"0.0120","T18-3":"0.0067","T26-6":"0.0238","T30-2":"0.0180","T31-6":"0.0134","T36-4":"0.0092","T43-1":"0.0045","T52-6":"","V32-6":"","V38-9":"","V44-2":"","V47-6":"","V69-3":"","V77-5":"","V78-6":""},{"Metabolite":"Glycocholic acid","T12-4":"0.4530","T18-3":"0.3390","T26-6":"0.4100","T30-2":"0.3650","T31-6":"0.1750","T36-4":"0.3710","T43-1":"0.2190","T52-6":"","V32-6":"","V38-9":"","V44-2":"","V47-6":"","V69-3":"","V77-5":"","V78-6":""},{"Metabolite":"Glycodeoxycholic acid","T12-4":"0.0379","T18-3":"0.0188","T26-6":"0.0318","T30-2":"0.0179","T31-6":"0.0280","T36-4":"0.0120","T43-1":"0.0234","T52-6":"","V32-6":"","V38-9":"","V44-2":"","V47-6":"","V69-3":"","V77-5":"","V78-6":""},{"Metabolite":"Glycohyocholic acid","T12-4":"0.1753","T18-3":"0.0753","T26-6":"0.2086","T30-2":"0.1765","T31-6":"0.0055","T36-4":"0.0000","T43-1":"0.1146","T52-6":"","V32-6":"","V38-9":"","V44-2":"","V47-6":"","V69-3":"","V77-5":"","V78-6":""},{"Metabolite":"Glycohyodeoxycholic acid","T12-4":"0.0172","T18-3":"0.0053","T26-6":"0.0092","T30-2":"0.0100","T31-6":"0.0055","T36-4":"0.0066","T43-1":"0.0082","T52-6":"","V32-6":"","V38-9":"","V44-2":"","V47-6":"","V69-3":"","V77-5":"","V78-6":""},{"Metabolite":"Glycolithocholic acid","T12-4":"0.0211","T18-3":"0.0194","T26-6":"0.0148","T30-2":"0.0696","T31-6":"0.0175","T36-4":"0.0087","T43-1":"0.0135","T52-6":"","V32-6":"","V38-9":"","V44-2":"","V47-6":"","V69-3":"","V77-5":"","V78-6":""},{"Metabolite":"Glycoursodeoxycholic acid","T12-4":"0.0123","T18-3":"0.0148","T26-6":"0.0195","T30-2":"0.0142","T31-6":"0.0129","T36-4":"0.0192","T43-1":"0.0081","T52-6":"","V32-6":"","V38-9":"","V44-2":"","V47-6":"","V69-3":"","V77-5":"","V78-6":""},{"Metabolite":"Hyocholic acid","T12-4":"0.3883","T18-3":"0.0000","T26-6":"0.3292","T30-2":"0.1262","T31-6":"0.5238","T36-4":"0.3917","T43-1":"0.9114","T52-6":"","V32-6":"","V38-9":"","V44-2":"","V47-6":"","V69-3":"","V77-5":"","V78-6":""},{"Metabolite":"Hyodeoxycholic acid","T12-4":"0.2061","T18-3":"0.0884","T26-6":"0.2681","T30-2":"0.0616","T31-6":"0.1555","T36-4":"0.0331","T43-1":"0.8827","T52-6":"","V32-6":"","V38-9":"","V44-2":"","V47-6":"","V69-3":"","V77-5":"","V78-6":""},{"Metabolite":"Murocholic acid screen","T12-4":"0.2960","T18-3":"0.0000","T26-6":"0.2622","T30-2":"0.0247","T31-6":"0.1734","T36-4":"0.0848","T43-1":"0.9070","T52-6":"","V32-6":"","V38-9":"","V44-2":"","V47-6":"","V69-3":"","V77-5":"","V78-6":""},{"Metabolite":"Taurochenodeoxycholic acid","T12-4":"5.3400","T18-3":"6.1500","T26-6":"23.8000","T30-2":"16.4000","T31-6":"12.5000","T36-4":"8.1200","T43-1":"7.6100","T52-6":"","V32-6":"","V38-9":"","V44-2":"","V47-6":"","V69-3":"","V77-5":"","V78-6":""},{"Metabolite":"Taurocholic acid","T12-4":"210.0000","T18-3":"203.0000","T26-6":"204.0000","T30-2":"208.0000","T31-6":"121.0000","T36-4":"176.0000","T43-1":"219.0000","T52-6":"","V32-6":"","V38-9":"","V44-2":"","V47-6":"","V69-3":"","V77-5":"","V78-6":""},{"Metabolite":"Taurodeoxycholic acid","T12-4":"18.6000","T18-3":"15.2000","T26-6":"39.2000","T30-2":"17.6000","T31-6":"29.8000","T36-4":"10.0000","T43-1":"27.3000","T52-6":"","V32-6":"","V38-9":"","V44-2":"","V47-6":"","V69-3":"","V77-5":"","V78-6":""},{"Metabolite":"Taurohyocholic acid","T12-4":"0.1960","T18-3":"0.1587","T26-6":"0.2763","T30-2":"0.1301","T31-6":"0.0367","T36-4":"0.0000","T43-1":"0.2657","T52-6":"","V32-6":"","V38-9":"","V44-2":"","V47-6":"","V69-3":"","V77-5":"","V78-6":""},{"Metabolite":"Taurolithocholic acid","T12-4":"3.0800","T18-3":"1.2800","T26-6":"2.8500","T30-2":"1.0100","T31-6":"3.4800","T36-4":"1.0300","T43-1":"1.2800","T52-6":"","V32-6":"","V38-9":"","V44-2":"","V47-6":"","V69-3":"","V77-5":"","V78-6":""},{"Metabolite":"Tauroursodeoxycholic acid","T12-4":"15.1000","T18-3":"14.2000","T26-6":"22.2000","T30-2":"14.1000","T31-6":"16.8000","T36-4":"13.0000","T43-1":"14.0000","T52-6":"","V32-6":"","V38-9":"","V44-2":"","V47-6":"","V69-3":"","V77-5":"","V78-6":""},{"Metabolite":"Tauro-α-Muricholic acid","T12-4":"21.6000","T18-3":"15.8000","T26-6":"31.2000","T30-2":"17.9000","T31-6":"18.0000","T36-4":"17.5000","T43-1":"15.4000","T52-6":"","V32-6":"","V38-9":"","V44-2":"","V47-6":"","V69-3":"","V77-5":"","V78-6":""},{"Metabolite":"Tauro-β-Muricholic acid","T12-4":"79.9000","T18-3":"62.2000","T26-6":"65.5000","T30-2":"46.4000","T31-6":"45.8000","T36-4":"79.2000","T43-1":"76.1000","T52-6":"","V32-6":"","V38-9":"","V44-2":"","V47-6":"","V69-3":"","V77-5":"","V78-6":""},{"Metabolite":"Tauro-ω-Muricholic acid","T12-4":"76.1000","T18-3":"45.2000","T26-6":"71.7000","T30-2":"63.0000","T31-6":"30.7000","T36-4":"32.6000","T43-1":"96.5000","T52-6":"","V32-6":"","V38-9":"","V44-2":"","V47-6":"","V69-3":"","V77-5":"","V78-6":""},{"Metabolite":"Trihydroxycholestanoic acid (screening*)","T12-4":"0.0919","T18-3":"0.0000","T26-6":"0.0964","T30-2":"0.0783","T31-6":"0.0442","T36-4":"0.0660","T43-1":"0.0559","T52-6":"","V32-6":"","V38-9":"","V44-2":"","V47-6":"","V69-3":"","V77-5":"","V78-6":""},{"Metabolite":"Ursodeoxycholic acid","T12-4":"0.1940","T18-3":"0.2280","T26-6":"0.3630","T30-2":"0.0586","T31-6":"0.3380","T36-4":"0.0767","T43-1":"0.8390","T52-6":"","V32-6":"","V38-9":"","V44-2":"","V47-6":"","V69-3":"","V77-5":"","V78-6":""},{"Metabolite":"α-Muricholic acid","T12-4":"1.5900","T18-3":"0.5040","T26-6":"1.5800","T30-2":"0.3150","T31-6":"1.0600","T36-4":"0.4790","T43-1":"2.6100","T52-6":"","V32-6":"","V38-9":"","V44-2":"","V47-6":"","V69-3":"","V77-5":"","V78-6":""},{"Metabolite":"β-Muricholic acid","T12-4":"3.1400","T18-3":"1.6200","T26-6":"3.2400","T30-2":"0.8260","T31-6":"2.3600","T36-4":"1.5000","T43-1":"7.8900","T52-6":"","V32-6":"","V38-9":"","V44-2":"","V47-6":"","V69-3":"","V77-5":"","V78-6":""},{"Metabolite":"ω-Muricholic acid","T12-4":"1.9900","T18-3":"0.6820","T26-6":"1.9300","T30-2":"0.5440","T31-6":"0.8180","T36-4":"0.3240","T43-1":"6.4000","T52-6":"","V32-6":"","V38-9":"","V44-2":"","V47-6":"","V69-3":"","V77-5":"","V78-6":""}],

"Metabolites":[{"Metabolite":"Chenodeoxycholic acid","moverz_quant":"","ri":"","ri_type":"","pubchem_id":"44135443","inchi_key":"","kegg_id":"","other_id":"HMDB00518","other_id_type":"UCDavis_Newman_ID"},{"Metabolite":"Cholic acid","moverz_quant":"","ri":"","ri_type":"","pubchem_id":"221493","inchi_key":"","kegg_id":"","other_id":"HMDB00619","other_id_type":"UCDavis_Newman_ID"},{"Metabolite":"Deoxycholic acid","moverz_quant":"","ri":"","ri_type":"","pubchem_id":"222528","inchi_key":"","kegg_id":"","other_id":"HMDB00626","other_id_type":"UCDavis_Newman_ID"},{"Metabolite":"Dihydroxycholestanoic acid","moverz_quant":"","ri":"","ri_type":"","pubchem_id":"","inchi_key":"","kegg_id":"","other_id":"HMDB01974","other_id_type":"UCDavis_Newman_ID"},{"Metabolite":"Glychochenodeoxycholic acid","moverz_quant":"","ri":"","ri_type":"","pubchem_id":"","inchi_key":"","kegg_id":"","other_id":"HMDB00637","other_id_type":"UCDavis_Newman_ID"},{"Metabolite":"Glycocholic acid","moverz_quant":"","ri":"","ri_type":"","pubchem_id":"755","inchi_key":"","kegg_id":"","other_id":"HMDB00138","other_id_type":"UCDavis_Newman_ID"},{"Metabolite":"Glycodeoxycholic acid","moverz_quant":"","ri":"","ri_type":"","pubchem_id":"3035026","inchi_key":"","kegg_id":"","other_id":"HMDB00631","other_id_type":"UCDavis_Newman_ID"},{"Metabolite":"Glycohyocholic acid","moverz_quant":"","ri":"","ri_type":"","pubchem_id":"","inchi_key":"","kegg_id":"","other_id":"","other_id_type":""},{"Metabolite":"Glycohyodeoxycholic acid","moverz_quant":"","ri":"","ri_type":"","pubchem_id":"114611","inchi_key":"","kegg_id":"","other_id":"","other_id_type":""},{"Metabolite":"Glycolithocholic acid","moverz_quant":"","ri":"","ri_type":"","pubchem_id":"115245","inchi_key":"","kegg_id":"","other_id":"HMDB00698","other_id_type":"UCDavis_Newman_ID"},{"Metabolite":"Glycoursodeoxycholic acid","moverz_quant":"","ri":"","ri_type":"","pubchem_id":"","inchi_key":"","kegg_id":"","other_id":"HMDB00708","other_id_type":"UCDavis_Newman_ID"},{"Metabolite":"Hyocholic acid","moverz_quant":"","ri":"","ri_type":"","pubchem_id":"92805","inchi_key":"","kegg_id":"","other_id":"HMDB00865","other_id_type":"UCDavis_Newman_ID"},{"Metabolite":"Hyodeoxycholic acid","moverz_quant":"","ri":"","ri_type":"","pubchem_id":"9963687","inchi_key":"","kegg_id":"","other_id":"","other_id_type":""},{"Metabolite":"Murocholic acid screen","moverz_quant":"","ri":"","ri_type":"","pubchem_id":"","inchi_key":"","kegg_id":"","other_id":"HMDB00811","other_id_type":"UCDavis_Newman_ID"},{"Metabolite":"Taurochenodeoxycholic acid","moverz_quant":"","ri":"","ri_type":"","pubchem_id":"387316","inchi_key":"","kegg_id":"","other_id":"HMDB00951","other_id_type":"UCDavis_Newman_ID"},{"Metabolite":"Taurocholic acid","moverz_quant":"","ri":"","ri_type":"","pubchem_id":"444349","inchi_key":"","kegg_id":"","other_id":"HMDB00036","other_id_type":"UCDavis_Newman_ID"},{"Metabolite":"Taurodeoxycholic acid","moverz_quant":"","ri":"","ri_type":"","pubchem_id":"10594","inchi_key":"","kegg_id":"","other_id":"HMDB00896","other_id_type":"UCDavis_Newman_ID"},{"Metabolite":"Taurohyocholic acid","moverz_quant":"","ri":"","ri_type":"","pubchem_id":"","inchi_key":"","kegg_id":"","other_id":"","other_id_type":""},{"Metabolite":"Taurolithocholic acid","moverz_quant":"","ri":"","ri_type":"","pubchem_id":"53477716","inchi_key":"","kegg_id":"","other_id":"HMDB00722","other_id_type":"UCDavis_Newman_ID"},{"Metabolite":"Tauroursodeoxycholic acid","moverz_quant":"","ri":"","ri_type":"","pubchem_id":"9848818","inchi_key":"","kegg_id":"","other_id":"HMDB00874","other_id_type":"UCDavis_Newman_ID"},{"Metabolite":"Tauro-α-Muricholic acid","moverz_quant":"","ri":"","ri_type":"","pubchem_id":"","inchi_key":"","kegg_id":"","other_id":"","other_id_type":""},{"Metabolite":"Tauro-β-Muricholic acid","moverz_quant":"","ri":"","ri_type":"","pubchem_id":"","inchi_key":"","kegg_id":"","other_id":"HMDB00932","other_id_type":"UCDavis_Newman_ID"},{"Metabolite":"Tauro-ω-Muricholic acid","moverz_quant":"","ri":"","ri_type":"","pubchem_id":"21124703","inchi_key":"","kegg_id":"","other_id":"","other_id_type":""},{"Metabolite":"Trihydroxycholestanoic acid (screening*)","moverz_quant":"","ri":"","ri_type":"","pubchem_id":"","inchi_key":"","kegg_id":"","other_id":"HMDB02163","other_id_type":"UCDavis_Newman_ID"},{"Metabolite":"Ursodeoxycholic acid","moverz_quant":"","ri":"","ri_type":"","pubchem_id":"31401","inchi_key":"","kegg_id":"","other_id":"HMDB00946","other_id_type":"UCDavis_Newman_ID"},{"Metabolite":"α-Muricholic acid","moverz_quant":"","ri":"","ri_type":"","pubchem_id":"5283852","inchi_key":"","kegg_id":"","other_id":"HMDB00506","other_id_type":"UCDavis_Newman_ID"},{"Metabolite":"β-Muricholic acid","moverz_quant":"","ri":"","ri_type":"","pubchem_id":"5283853","inchi_key":"","kegg_id":"","other_id":"HMDB00415","other_id_type":"UCDavis_Newman_ID"},{"Metabolite":"ω-Muricholic acid","moverz_quant":"","ri":"","ri_type":"","pubchem_id":"5283851","inchi_key":"","kegg_id":"","other_id":"HMDB00364","other_id_type":"UCDavis_Newman_ID"}]
}

}