{
"METABOLOMICS WORKBENCH":{"STUDY_ID":"ST000273","ANALYSIS_ID":"AN000436","VERSION":"1","CREATED_ON":"08-09-2023"},

"PROJECT":{"PROJECT_TITLE":"Longitudinal Studies of HIV-Associated Bacterial Pneumonia","PROJECT_SUMMARY":"SCFA metabolites, increased Treg, reduced Th17 lymphocytes and blunted immune response ex vivo","INSTITUTE":"New York University","DEPARTMENT":"Pulmonary Medicine","LABORATORY":"Weiden Lab","LAST_NAME":"Weiden","FIRST_NAME":"Michael","ADDRESS":"New York","EMAIL":"michael.weiden@nyumc.org","PHONE":"212-263-6479","DOI":"http://dx.doi.org/10.21228/M8BP4D"},

"STUDY":{"STUDY_TITLE":"Short-chain fatty acid analysis in bronchoalveolar lavage fluid (BAL SCFA)","STUDY_TYPE":"We will correlate the bacterial gene abundance with the metabolite concentration","STUDY_SUMMARY":"The study is intended to find if correlation exists between the abundance of bacterial gene for pyruvate ferredoxin oxidoreductase (PFOR) and short-chain fatty acids concentration in bronchoalveolar lavage fluid from patients with HIV-Associated Bacterial Pneumonia.","INSTITUTE":"University of Michigan; New York University","DEPARTMENT":"Pulmonary Medicine","LABORATORY":"Weiden Lab(New York University School of Medicine)","LAST_NAME":"Weiden","FIRST_NAME":"Michael","ADDRESS":"New York","EMAIL":"michael.weiden@nyumc.org","PHONE":"212-263-6479","SUBMIT_DATE":"2014-03-26"},

"SUBJECT":{"SUBJECT_TYPE":"Human","SUBJECT_SPECIES":"Homo sapiens","TAXONOMY_ID":"9606","SPECIES_GROUP":"Human"},
"SUBJECT_SAMPLE_FACTORS":[
{
"Subject ID":"-",
"Sample ID":"S00013188",
"Factors":{"PFOR level":"High"}
},
{
"Subject ID":"-",
"Sample ID":"S00013189",
"Factors":{"PFOR level":"High"}
},
{
"Subject ID":"-",
"Sample ID":"S00013190",
"Factors":{"PFOR level":"High"}
},
{
"Subject ID":"-",
"Sample ID":"S00013191",
"Factors":{"PFOR level":"High"}
},
{
"Subject ID":"-",
"Sample ID":"S00013192",
"Factors":{"PFOR level":"High"}
},
{
"Subject ID":"-",
"Sample ID":"S00013193",
"Factors":{"PFOR level":"High"}
},
{
"Subject ID":"-",
"Sample ID":"S00013194",
"Factors":{"PFOR level":"High"}
},
{
"Subject ID":"-",
"Sample ID":"S00013195",
"Factors":{"PFOR level":"High"}
},
{
"Subject ID":"-",
"Sample ID":"S00013196",
"Factors":{"PFOR level":"High"}
},
{
"Subject ID":"-",
"Sample ID":"S00013197",
"Factors":{"PFOR level":"High"}
},
{
"Subject ID":"-",
"Sample ID":"S00013198",
"Factors":{"PFOR level":"High"}
},
{
"Subject ID":"-",
"Sample ID":"S00013199",
"Factors":{"PFOR level":"High"}
},
{
"Subject ID":"-",
"Sample ID":"S00013200",
"Factors":{"PFOR level":"High"}
},
{
"Subject ID":"-",
"Sample ID":"S00013201",
"Factors":{"PFOR level":"High"}
},
{
"Subject ID":"-",
"Sample ID":"S00013202",
"Factors":{"PFOR level":"High"}
},
{
"Subject ID":"-",
"Sample ID":"S00013203",
"Factors":{"PFOR level":"High"}
},
{
"Subject ID":"-",
"Sample ID":"S00013204",
"Factors":{"PFOR level":"High"}
},
{
"Subject ID":"-",
"Sample ID":"S00013205",
"Factors":{"PFOR level":"High"}
},
{
"Subject ID":"-",
"Sample ID":"S00013206",
"Factors":{"PFOR level":"High"}
},
{
"Subject ID":"-",
"Sample ID":"S00013207",
"Factors":{"PFOR level":"High"}
},
{
"Subject ID":"-",
"Sample ID":"S00013208",
"Factors":{"PFOR level":"High"}
},
{
"Subject ID":"-",
"Sample ID":"S00013209",
"Factors":{"PFOR level":"High"}
},
{
"Subject ID":"-",
"Sample ID":"S00013210",
"Factors":{"PFOR level":"High"}
},
{
"Subject ID":"-",
"Sample ID":"S00013211",
"Factors":{"PFOR level":"High"}
},
{
"Subject ID":"-",
"Sample ID":"S00013212",
"Factors":{"PFOR level":"High"}
},
{
"Subject ID":"-",
"Sample ID":"S00013213",
"Factors":{"PFOR level":"High"}
},
{
"Subject ID":"-",
"Sample ID":"S00013214",
"Factors":{"PFOR level":"High"}
},
{
"Subject ID":"-",
"Sample ID":"S00013176",
"Factors":{"PFOR level":"Low"}
},
{
"Subject ID":"-",
"Sample ID":"S00013177",
"Factors":{"PFOR level":"Low"}
},
{
"Subject ID":"-",
"Sample ID":"S00013178",
"Factors":{"PFOR level":"Low"}
},
{
"Subject ID":"-",
"Sample ID":"S00013179",
"Factors":{"PFOR level":"Low"}
},
{
"Subject ID":"-",
"Sample ID":"S00013180",
"Factors":{"PFOR level":"Low"}
},
{
"Subject ID":"-",
"Sample ID":"S00013181",
"Factors":{"PFOR level":"Low"}
},
{
"Subject ID":"-",
"Sample ID":"S00013182",
"Factors":{"PFOR level":"Low"}
},
{
"Subject ID":"-",
"Sample ID":"S00013183",
"Factors":{"PFOR level":"Low"}
},
{
"Subject ID":"-",
"Sample ID":"S00013184",
"Factors":{"PFOR level":"Low"}
},
{
"Subject ID":"-",
"Sample ID":"S00013185",
"Factors":{"PFOR level":"Low"}
},
{
"Subject ID":"-",
"Sample ID":"S00013186",
"Factors":{"PFOR level":"Low"}
},
{
"Subject ID":"-",
"Sample ID":"S00013187",
"Factors":{"PFOR level":"Low"}
}
],
"COLLECTION":{"COLLECTION_SUMMARY":"--","SAMPLE_TYPE":"Bronchoalveolar Lavage Fluid"},

"TREATMENT":[],

"SAMPLEPREP":{"SAMPLEPREP_SUMMARY":"--","SAMPLEPREP_PROTOCOL_FILENAME":"SCFA_analysis_protocol-2015-03-10.docx"},

"CHROMATOGRAPHY":{"CHROMATOGRAPHY_SUMMARY":"--","METHODS_ID":"AQM030","METHODS_FILENAME":"WAXPLUS_100-200C_2_SIM.M.txt","INSTRUMENT_NAME":"--","COLUMN_NAME":"Phenomenex Zebron ZB-WAXplus (30m x 0.25mm,0.25um)","COLUMN_TEMPERATURE":"--","FLOW_GRADIENT":"--","FLOW_RATE":"--","SOLVENT_A":"--","SOLVENT_B":"--","CHROMATOGRAPHY_TYPE":"GC"},

"ANALYSIS":{"LABORATORY_NAME":"MRC2 (University of Michigan)","ANALYSIS_TYPE":"MS","ACQUISITION_ID":"AQM030","ACQUISITION_PARAMETERS_FILE":"WAXPLUS_100-200C_2_SIM.M.txt","PROCESSING_PARAMETERS_FILE":"EX00259-SCFA-Quant-methods.m.zip"},

"MS":{"INSTRUMENT_NAME":"Agilent 5975C","INSTRUMENT_TYPE":"Single quadrupole","MS_TYPE":"EI","ION_MODE":"POSITIVE"},

"MS_METABOLITE_DATA":{
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}

}