{
"METABOLOMICS WORKBENCH":{"STUDY_ID":"ST000762","ANALYSIS_ID":"AN001200","VERSION":"1","CREATED_ON":"July 4, 2017, 3:22 pm"},

"PROJECT":{"PROJECT_TITLE":"Scleroderma and exercise","PROJECT_TYPE":"MS analysis","PROJECT_SUMMARY":"Plasma Nucleotide/adenosine concentrations in patiens with scleroderma depending on exercise","INSTITUTE":"University of Michigan","DEPARTMENT":"Internal Medicine-Cardiology","LABORATORY":"Visovatti Lab","LAST_NAME":"Visovatti","FIRST_NAME":"Scott","ADDRESS":"Ann Arbor, MI","EMAIL":"shv@med.umich.edu","PHONE":"734-657-6917"},

"STUDY":{"STUDY_TITLE":"Plasma Nucleotide/adenosine concentrations in patiens with scleroderma depending on exercise","STUDY_TYPE":"MS analysis","STUDY_SUMMARY":"This experiment was performed using the following cohorts: 1) healthy controls, 2) patients with scleroderma at low risk for pulmonary hypertension, 3) pateints with scleroderma at high risk for pulmonary hypertension (SSc Cath). Whole blood was drawn directly into stop soilution (1:1 ratio) at rest and again at peak exercise for each human subject. The samples were processed to plasma by MCRU and stored at -80 in the Biorepository.","INSTITUTE":"University of Michigan","DEPARTMENT":"Biomedical Research Core Facilities","LABORATORY":"Metabolomics core","LAST_NAME":"Kachman","FIRST_NAME":"Maureen","ADDRESS":"6300 Brehm Tower, 1000 Wall Street, Ann Arbor, MI 48105-5714","EMAIL":"mkachman@med.umich.edu","PHONE":"(734) 232-8175","NUM_GROUPS":"5","TOTAL_SUBJECTS":"26"},

"SUBJECT":{"SUBJECT_TYPE":"Human","SUBJECT_SPECIES":"Homo sapiens","TAXONOMY_ID":"9606"},
"SUBJECT_SAMPLE_FACTORS":[
{
"Subject ID":"SU0012506",
"Sample ID":"S00019091",
"Factors":{"Exercise":"No","Group":"Low Risk SSc"}
},
{
"Subject ID":"SU0012506",
"Sample ID":"S00019092",
"Factors":{"Exercise":"Yes","Group":"Low Risk SSc"}
},
{
"Subject ID":"SU0012507",
"Sample ID":"S00019093",
"Factors":{"Exercise":"No","Group":"Low Risk SSc"}
},
{
"Subject ID":"SU0012507",
"Sample ID":"S00019094",
"Factors":{"Exercise":"Yes","Group":"Low Risk SSc"}
},
{
"Subject ID":"SU0012508",
"Sample ID":"S00019095",
"Factors":{"Exercise":"No","Group":"SSc Cath"}
},
{
"Subject ID":"SU0012508",
"Sample ID":"S00019096",
"Factors":{"Exercise":"Yes","Group":"SSc Cath"}
},
{
"Subject ID":"SU0012509",
"Sample ID":"S00019097",
"Factors":{"Exercise":"No","Group":"Low Risk SSc"}
},
{
"Subject ID":"SU0012509",
"Sample ID":"S00019098",
"Factors":{"Exercise":"Yes","Group":"Low Risk SSc"}
},
{
"Subject ID":"SU0012510",
"Sample ID":"S00019099",
"Factors":{"Exercise":"No","Group":"SSc Cath"}
},
{
"Subject ID":"SU0012510",
"Sample ID":"S00019100",
"Factors":{"Exercise":"Yes","Group":"SSc Cath"}
},
{
"Subject ID":"SU0012511",
"Sample ID":"S00019101",
"Factors":{"Exercise":"No","Group":"SSc Cath"}
},
{
"Subject ID":"SU0012511",
"Sample ID":"S00019102",
"Factors":{"Exercise":"Yes","Group":"SSc Cath"}
},
{
"Subject ID":"SU0012512",
"Sample ID":"S00019103",
"Factors":{"Exercise":"No","Group":"SSc Cath"}
},
{
"Subject ID":"SU0012512",
"Sample ID":"S00019104",
"Factors":{"Exercise":"Yes","Group":"SSc Cath"}
},
{
"Subject ID":"SU0012513",
"Sample ID":"S00019105",
"Factors":{"Exercise":"No","Group":"SSc Cath"}
},
{
"Subject ID":"SU0012514",
"Sample ID":"S00019106",
"Factors":{"Exercise":"No","Group":"Healthy"}
},
{
"Subject ID":"SU0012514",
"Sample ID":"S00019107",
"Factors":{"Exercise":"Yes","Group":"Healthy"}
},
{
"Subject ID":"SU0012515",
"Sample ID":"S00019108",
"Factors":{"Exercise":"No","Group":"Healthy"}
},
{
"Subject ID":"SU0012515",
"Sample ID":"S00019109",
"Factors":{"Exercise":"Yes","Group":"Healthy"}
},
{
"Subject ID":"SU0012516",
"Sample ID":"S00019110",
"Factors":{"Exercise":"No","Group":"Healthy"}
},
{
"Subject ID":"SU0012516",
"Sample ID":"S00019111",
"Factors":{"Exercise":"Yes","Group":"Healthy"}
},
{
"Subject ID":"SU0012517",
"Sample ID":"S00019112",
"Factors":{"Exercise":"No","Group":"Low Risk SSc"}
},
{
"Subject ID":"SU0012517",
"Sample ID":"S00019113",
"Factors":{"Exercise":"Yes","Group":"Low Risk SSc"}
},
{
"Subject ID":"SU0012518",
"Sample ID":"S00019114",
"Factors":{"Exercise":"No","Group":"Healthy"}
},
{
"Subject ID":"SU0012518",
"Sample ID":"S00019115",
"Factors":{"Exercise":"Yes","Group":"Healthy"}
},
{
"Subject ID":"SU0012519",
"Sample ID":"S00019116",
"Factors":{"Exercise":"No","Group":"Healthy"}
},
{
"Subject ID":"SU0012519",
"Sample ID":"S00019117",
"Factors":{"Exercise":"Yes","Group":"Healthy"}
},
{
"Subject ID":"SU0012520",
"Sample ID":"S00019118",
"Factors":{"Exercise":"No","Group":"Healthy"}
},
{
"Subject ID":"SU0012520",
"Sample ID":"S00019119",
"Factors":{"Exercise":"Yes","Group":"Healthy"}
},
{
"Subject ID":"SU0012521",
"Sample ID":"S00019120",
"Factors":{"Exercise":"No","Group":"Healthy"}
},
{
"Subject ID":"SU0012521",
"Sample ID":"S00019121",
"Factors":{"Exercise":"Yes","Group":"Healthy"}
},
{
"Subject ID":"SU0012522",
"Sample ID":"S00019122",
"Factors":{"Exercise":"No","Group":"Low Risk SSc"}
},
{
"Subject ID":"SU0012522",
"Sample ID":"S00019123",
"Factors":{"Exercise":"Yes","Group":"Low Risk SSc"}
},
{
"Subject ID":"SU0012523",
"Sample ID":"S00019124",
"Factors":{"Exercise":"No","Group":"SSc Cath"}
},
{
"Subject ID":"SU0012523",
"Sample ID":"S00019125",
"Factors":{"Exercise":"Yes","Group":"SSc Cath"}
},
{
"Subject ID":"SU0012524",
"Sample ID":"S00019126",
"Factors":{"Exercise":"No","Group":"SSc Cath"}
},
{
"Subject ID":"SU0012524",
"Sample ID":"S00019127",
"Factors":{"Exercise":"Yes","Group":"SSc Cath"}
},
{
"Subject ID":"SU0012525",
"Sample ID":"S00019128",
"Factors":{"Exercise":"No","Group":"SSc Cath"}
},
{
"Subject ID":"SU0012525",
"Sample ID":"S00019129",
"Factors":{"Exercise":"Yes","Group":"SSc Cath"}
},
{
"Subject ID":"SU0012526",
"Sample ID":"S00019130",
"Factors":{"Exercise":"No","Group":"Low Risk SSc"}
},
{
"Subject ID":"SU0012526",
"Sample ID":"S00019131",
"Factors":{"Exercise":"Yes","Group":"Low Risk SSc"}
},
{
"Subject ID":"SU0012527",
"Sample ID":"S00019132",
"Factors":{"Exercise":"No","Group":"Healthy"}
},
{
"Subject ID":"SU0012527",
"Sample ID":"S00019133",
"Factors":{"Exercise":"Yes","Group":"Healthy"}
},
{
"Subject ID":"SU0012528",
"Sample ID":"S00019134",
"Factors":{"Exercise":"No","Group":"SSc Cath"}
},
{
"Subject ID":"SU0012528",
"Sample ID":"S00019135",
"Factors":{"Exercise":"Yes","Group":"SSc Cath"}
},
{
"Subject ID":"SU0012529",
"Sample ID":"S00019136",
"Factors":{"Exercise":"No","Group":"SSc Cath"}
},
{
"Subject ID":"SU0012529",
"Sample ID":"S00019137",
"Factors":{"Exercise":"Yes","Group":"SSc Cath"}
},
{
"Subject ID":"SU0012530",
"Sample ID":"S00019138",
"Factors":{"Exercise":"No","Group":"Healthy"}
},
{
"Subject ID":"SU0012530",
"Sample ID":"S00019139",
"Factors":{"Exercise":"Yes","Group":"Healthy"}
},
{
"Subject ID":"SU0012505",
"Sample ID":"S00019140",
"Factors":{"Exercise":"No","Group":"SSc Cath"}
},
{
"Subject ID":"SU0012505",
"Sample ID":"S00019141",
"Factors":{"Exercise":"Yes","Group":"SSc Cath"}
}
],
"COLLECTION":{"COLLECTION_SUMMARY":"-"},

"TREATMENT":{"TREATMENT_SUMMARY":"-"},

"SAMPLEPREP":{"SAMPLEPREP_SUMMARY":"-","SAMPLEPREP_PROTOCOL_FILENAME":"A011 - Glycolysis-TCA-nucleotides.pdf"},

"CHROMATOGRAPHY":{"CHROMATOGRAPHY_TYPE":"HILIC","INSTRUMENT_NAME":"Agilent","COLUMN_NAME":"Phenomenex Luna NH2 (150 x 1mm, 3um)"},

"ANALYSIS":{"ANALYSIS_TYPE":"MS","ANALYSIS_PROTOCOL_FILE":"A011 - Glycolysis-TCA-nucleotides.pdf"},

"MS":{"MS_COMMENTS":"-","INSTRUMENT_NAME":"Agilent 6520B QTOF","INSTRUMENT_TYPE":"QTOF","MS_TYPE":"ESI","ION_MODE":"NEGATIVE"},

"MS_METABOLITE_DATA":{
"Units":"nM",

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}

}