{
"METABOLOMICS WORKBENCH":{"STUDY_ID":"ST000828","ANALYSIS_ID":"AN001836","VERSION":"1","CREATED_ON":"January 15, 2019, 12:36 pm"},

"PROJECT":{"PROJECT_TITLE":"Metabolic regulation by PARP-1 in myofibroblast differentiation and fibrosis","PROJECT_TYPE":"MS analysis","PROJECT_SUMMARY":"Analysis of wild type lung tissue after saline or bleomycin treatment","INSTITUTE":"University of Michigan","DEPARTMENT":"Deaprtment of Pathology","LABORATORY":"Sem H. Phan","LAST_NAME":"Hu","FIRST_NAME":"Biao","ADDRESS":"Ann Arbor, MI","EMAIL":"biaohu@med.umich.edu","PHONE":"734-7635731"},

"STUDY":{"STUDY_TITLE":"Metabolic analysis of Parp1 ko/wt Saline & Bleo Mouse Lung Fiboblasts and Human IPF & Normal Lung Fiboblasts 3","STUDY_TYPE":"MS analysis","STUDY_SUMMARY":"Glycolysis/TCA/Nucleotide analysis (especially interested in alpha-ketoglutarate) and NAD+ and related metabolite analysis for all samples","INSTITUTE":"University of Michigan","DEPARTMENT":"Biomedical Research Core Facilities","LABORATORY":"Metabolomics core","LAST_NAME":"Kachman","FIRST_NAME":"Maureen","ADDRESS":"6300 Brehm Tower, 1000 Wall Street, Ann Arbor, MI 48105-5714","EMAIL":"mkachman@med.umich.edu","PHONE":"(734) 232-8175","NUM_GROUPS":"6","TOTAL_SUBJECTS":"16"},

"SUBJECT":{"SUBJECT_TYPE":"HUMAN","SUBJECT_SPECIES":"Homo sapiens","TAXONOMY_ID":"9606"},
"SUBJECT_SAMPLE_FACTORS":[
{
"Subject ID":"SU0004492",
"Sample ID":"S00015469",
"Factors":{"Sample type":"Tissues","Species":"Mus musculus","bleomycin/IPF":"N","saline/HLF":"Y","wt B6":"Y"}
},
{
"Subject ID":"SU0004493",
"Sample ID":"S00015470",
"Factors":{"Sample type":"Tissues","Species":"Mus musculus","bleomycin/IPF":"N","saline/HLF":"Y","wt B6":"Y"}
},
{
"Subject ID":"SU0004494",
"Sample ID":"S00015471",
"Factors":{"Sample type":"Tissues","Species":"Mus musculus","bleomycin/IPF":"Y","saline/HLF":"N","wt B6":"Y"}
},
{
"Subject ID":"SU0004495",
"Sample ID":"S00015472",
"Factors":{"Sample type":"Tissues","Species":"Mus musculus","bleomycin/IPF":"Y","saline/HLF":"N","wt B6":"Y"}
},
{
"Subject ID":"SU0004496",
"Sample ID":"S00015473",
"Factors":{"Sample type":"Tissues","Species":"Mus musculus","bleomycin/IPF":"Y","saline/HLF":"N","wt B6":"Y"}
},
{
"Subject ID":"SU0004497",
"Sample ID":"S00015474",
"Factors":{"Sample type":"Tissues","Species":"Mus musculus","bleomycin/IPF":"Y","saline/HLF":"N","wt B6":"Y"}
},
{
"Subject ID":"SU0004498",
"Sample ID":"S00015475",
"Factors":{"Sample type":"Cells","Species":"Homo sapiens","bleomycin/IPF":"N","saline/HLF":"Y","wt B6":"N"}
},
{
"Subject ID":"SU0004499",
"Sample ID":"S00015476",
"Factors":{"Sample type":"Cells","Species":"Homo sapiens","bleomycin/IPF":"N","saline/HLF":"Y","wt B6":"N"}
},
{
"Subject ID":"SU0004500",
"Sample ID":"S00015477",
"Factors":{"Sample type":"Cells","Species":"Homo sapiens","bleomycin/IPF":"N","saline/HLF":"Y","wt B6":"N"}
},
{
"Subject ID":"SU0004501",
"Sample ID":"S00015478",
"Factors":{"Sample type":"Cells","Species":"Homo sapiens","bleomycin/IPF":"N","saline/HLF":"Y","wt B6":"N"}
},
{
"Subject ID":"SU0004502",
"Sample ID":"S00015479",
"Factors":{"Sample type":"Cells","Species":"Homo sapiens","bleomycin/IPF":"N","saline/HLF":"Y","wt B6":"N"}
},
{
"Subject ID":"SU0004503",
"Sample ID":"S00015480",
"Factors":{"Sample type":"Cells","Species":"Homo sapiens","bleomycin/IPF":"Y","saline/HLF":"N","wt B6":"N"}
},
{
"Subject ID":"SU0004504",
"Sample ID":"S00015481",
"Factors":{"Sample type":"Cells","Species":"Homo sapiens","bleomycin/IPF":"Y","saline/HLF":"N","wt B6":"N"}
},
{
"Subject ID":"SU0004505",
"Sample ID":"S00015482",
"Factors":{"Sample type":"Cells","Species":"Homo sapiens","bleomycin/IPF":"Y","saline/HLF":"N","wt B6":"N"}
},
{
"Subject ID":"SU0004506",
"Sample ID":"S00015483",
"Factors":{"Sample type":"Cells","Species":"Homo sapiens","bleomycin/IPF":"Y","saline/HLF":"N","wt B6":"N"}
},
{
"Subject ID":"SU0004507",
"Sample ID":"S00015484",
"Factors":{"Sample type":"Cells","Species":"Homo sapiens","bleomycin/IPF":"Y","saline/HLF":"N","wt B6":"N"}
}
],
"COLLECTION":{"COLLECTION_SUMMARY":"-","SAMPLE_TYPE":"Cultured cells"},

"TREATMENT":{"TREATMENT_SUMMARY":"-"},

"SAMPLEPREP":{"SAMPLEPREP_SUMMARY":"-","SAMPLEPREP_PROTOCOL_FILENAME":"A010-Ceramides.pdf"},

"CHROMATOGRAPHY":{"CHROMATOGRAPHY_TYPE":"HILIC","INSTRUMENT_NAME":"Agilent","COLUMN_NAME":"Phenomenex Luna NH2 (150 x 1mm, 3um)"},

"ANALYSIS":{"ANALYSIS_TYPE":"MS","ANALYSIS_PROTOCOL_FILE":"A011-Glycolysis-TCA-nucleotides.pdf","ACQUISITION_PARAMETERS_FILE":"QTOF-002-HILIC-35min-1mm.m"},

"MS":{"INSTRUMENT_NAME":"Agilent 6520B QTOF","INSTRUMENT_TYPE":"QTOF","MS_TYPE":"ESI","ION_MODE":"NEGATIVE","MS_COMMENTS":"none"},

"MS_METABOLITE_DATA":{
"Units":"uM",

"Data":[{"Metabolite":"PHOSPHOENOLPYRUVATE","S00015469":"","S00015470":"","S00015471":"","S00015472":"","S00015473":"","S00015474":"","S00015475":".0957662","S00015476":".1273109","S00015477":".262627","S00015478":".1784907","S00015479":".0631907","S00015480":".1120064","S00015481":".0970568","S00015482":".2332775","S00015483":".1411019","S00015484":".139734"},{"Metabolite":"D-ERYTHROSE 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}

}