{
"METABOLOMICS WORKBENCH":{"STUDY_ID":"ST001521","ANALYSIS_ID":"AN002536","VERSION":"1","CREATED_ON":"November 5, 2020, 1:50 pm"},

"PROJECT":{"PROJECT_TITLE":"Role of Diet in the Reconstitution of the Human Gut Microbiome and its Metabolome","PROJECT_TYPE":"Observational study","PROJECT_SUMMARY":"We studied the impact of three divergent diets, vegan, omnivore, and a synthetic enteral nutrition (EEN) diet lacking fiber, on the human gut microbiome and its metabolome in a longitudinal analysis that included a microbiota depletion intervention. Hybrid nontargeted LC-MS methods were used to profile stool and plasma metabolites.","INSTITUTE":"Broad Institute of MIT and Harvard","LAST_NAME":"Clish","FIRST_NAME":"Clary","ADDRESS":"415 Main Street, Cambridge, MA, 02142, USA","EMAIL":"clary@broadinstitute.org","PHONE":"617-714-7654","FUNDING_SOURCE":"Crohn’s & Colitis Foundation, P30 DK 050306, PennCHOP Microbiome Program, and the Penn Center for Nutritional Science and Medicine","CONTRIBUTORS":"Ceylan Tanes, Kyle Bittinger, Yuan Gao, Elliot S. Friedman, Lisa Nessel, Unmesha Roy Paladhi, Lillian Chau, Erika Panfen, Michael A. Fischbach, Jonathan Braun, Ramnik J. Xavier, Clary B. Clish, Hongzhe Li, Frederic D. Bushman, James D. Lewis, Gary D. Wu"},

"STUDY":{"STUDY_TITLE":"Plasma metabolites of known identity profiled using hybrid nontargeted methods (part-III)","STUDY_SUMMARY":"We determined the effect of diet on the composition and metabolic function of human gut microbiome using a controlled feeding experiment with three divergent diets (vegan, omnivore, and an exclusive enteral nutrition diet (EEN) devoid of dietary fiber) in the Food And Resulting Microbial Metabolites (FARMM) study. The study included an antibiotic and polyethylene glycol (Abx/PEG) intervention to dynamically assess the effect of diet on the reconstitution of the gut microbiota and its associated fecal and plasma metabolome. Samples from thirty healthy volunteers between the ages of 18 and 60, 10 mper diet group were analyzed. Self-reported vegans were required to have followed a vegan diet for a minimum of 6 months prior to enrollment. Key exclusion criteria included inflammatory bowel disease, celiac disease, or other chronic intestinal disorders; prior bowel resection surgery other than appendectomy; baseline bowel frequency less than every 2 days or greater than 3 times daily; creatinine concentration greater than the upper limit of normal; diabetes mellitus; currently smoking; body mass index (BMI) <18.5 or >35; and use of antibiotics and probiotics in the prior 6 months. The 10 vegans continued to follow their usual diet as outpatients. All participants completed the Diet History Questionnaire II (DHQ II), a food frequency questionnaire developed by the Risk Factor Monitoring and Methods Branch of the National Cancer Institute. The vegan participants also completed three 24 hour diet recalls with a dietitian in the week prior to starting antibiotics. We randomly assigned the 20 omnivores to receive an omnivore diet or EEN (Modulen® IBD) while residing in an inpatient research unit. The macronutrient composition of Modulen® is protein 36g, fat 47g, and carbohydrate 110g per 1000 Kcal. The two omnivore diets were engineered to have a similar composition to EEN. All the subjects consumed the menu A on day 11 and menu B on days 4 and 14. Diets for omnivores were constructed to provide the expected total calories required per day for the participant to maintain their current weight and were adjusted if there was weight gain or loss of more than 2.5 pounds. On days 6, 7, and 8, inpatients participants received vancomycin 500mg orally every 6 hours and neomycin 1000mg orally every 6 hours. On day 7, participants consumed 4L of polyethylene glycol (PEG) based bowel purgative (GoLytely®). Participants in the omnivore and EEN arms left the inpatient research unit only under the direct supervision of a research staff member. The vegan outpatients reported to the hospital twice on days 6,7 and 8 to receive antibiotics and to consume PEG on day 7. The first stool sample of each day of the inpatient groups was collected, aliquoted and frozen immediately at -80oC. Blood was collected on days 1, 5, 9, 12 and 15 from which plasma aliquots were immediately isolated and frozen at -80oC. The outpatient participants following the vegan diet also had blood collected on days 1, 5, 9, 12, and 15 from which plasma aliquots were immediately isolated and frozen at -80oC. Among these participants, the first stool of the day was collected at home daily and kept on ice packs until it was brought to the research unit where it could be aliquoted and frozen. Samples from vegans were received for aliquoting within 24 hours and on average within 4 hours (Wu et al., 2010). Day 0 stool was not collected from vegans since their diet did not change. The aliquoted amounts for all samples ranged from 500 mg to 1 g. The aliquots were taken from different areas of the sample. Remaining sample was then collected into one residual 50 ml conical tube with a tongue depressor. Any remaining stool was discarded. The University of Pennsylvania Institutional Review Board (IRB) approved the research protocol.","INSTITUTE":"Broad Institute of MIT and Harvard","LAST_NAME":"Clish","FIRST_NAME":"Clary","ADDRESS":"415 Main Street, Cambridge, MA, 02142, USA","EMAIL":"clary@broadinstitute.org","PHONE":"617-714-7654","NUM_GROUPS":"3","TOTAL_SUBJECTS":"30","NUM_MALES":"20","NUM_FEMALES":"10","STUDY_COMMENTS":"plasma samples collected at baseline and 3-4 timepoints"},

"SUBJECT":{"SUBJECT_TYPE":"Human","SUBJECT_SPECIES":"Homo sapiens","TAXONOMY_ID":"9606","AGE_OR_AGE_RANGE":"20-60","WEIGHT_OR_WEIGHT_RANGE":"BMI range: 20-35","GENDER":"Male and female","HUMAN_RACE":"White; American Indian/Alaskan Native; Black/African American","HUMAN_ETHNICITY":"Hispanic or Latino; Non-Hispanic or Latino","HUMAN_TRIAL_TYPE":"Intervention trial","HUMAN_EXCLUSION_CRITERIA":"Key exclusion criteria included inflammatory bowel disease, celiac disease, or other chronic intestinal disorders; prior bowel resection surgery other than appendectomy; baseline bowel frequency less than every 2 days or greater than 3 times daily; creatinine concentration greater than the upper limit of normal; diabetes mellitus; currently smoking; body mass index (BMI) <18.5 or >35; and use of antibiotics and probiotics in the prior 6 months"},
"SUBJECT_SAMPLE_FACTORS":[
{
"Subject ID":"9002",
"Sample ID":"9002-3-PA",
"Factors":{"Study_Diet":"Vegan","Age":"20","Sex":"Male","Race":"White","Time":"Day 15"},
"Additional sample data":{"Type":"Plasma","BMI":"21.3","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0078_WUG_FARMM_HIL-9002-3-PA.raw;0078_WUG_FARMM_LIP-9002-3-PA.raw;0078_WU_FARMM_CMH_9002-3-PA.raw;0078_WUG_FARMM_FFA-9002-3-PA.raw"}
},
{
"Subject ID":"9002",
"Sample ID":"9002-3-PB",
"Factors":{"Study_Diet":"Vegan","Age":"20","Sex":"Male","Race":"White","Time":"Day 12"},
"Additional sample data":{"Type":"Plasma","BMI":"21.3","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0076_WUG_FARMM_HIL-9002-3-PB.raw;0076_WUG_FARMM_LIP-9002-3-PB.raw;0076_WU_FARMM_CMH_9002-3-PB.raw;0076_WUG_FARMM_FFA-9002-3-PB.raw"}
},
{
"Subject ID":"9002",
"Sample ID":"9002-3-PC",
"Factors":{"Study_Diet":"Vegan","Age":"20","Sex":"Male","Race":"White","Time":"Day 9"},
"Additional sample data":{"Type":"Plasma","BMI":"21.3","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0079_WUG_FARMM_HIL-9002-3-PC.raw;0079_WUG_FARMM_LIP-9002-3-PC.raw;0079_WU_FARMM_CMH_9002-3-PC.raw;0079_WUG_FARMM_FFA-9002-3-PC.raw"}
},
{
"Subject ID":"9002",
"Sample ID":"9002-3-PD",
"Factors":{"Study_Diet":"Vegan","Age":"20","Sex":"Male","Race":"White","Time":"Day 5"},
"Additional sample data":{"Type":"Plasma","BMI":"21.3","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0080_WUG_FARMM_HIL-9002-3-PD.raw;0080_WUG_FARMM_LIP-9002-3-PD.raw;0080_WU_FARMM_CMH_9002-3-PD.raw;0080_WUG_FARMM_FFA-9002-3-PD.raw"}
},
{
"Subject ID":"9002",
"Sample ID":"9002-3-PE",
"Factors":{"Study_Diet":"Vegan","Age":"20","Sex":"Male","Race":"White","Time":"Baseline"},
"Additional sample data":{"Type":"Plasma","BMI":"21.3","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0077_WUG_FARMM_HIL-9002-3-PE.raw;0077_WUG_FARMM_LIP-9002-3-PE.raw;0077_WU_FARMM_CMH_9002-3-PE.raw;0077_WUG_FARMM_FFA-9002-3-PE.raw"}
},
{
"Subject ID":"9003",
"Sample ID":"9003-2-PA",
"Factors":{"Study_Diet":"Modulen","Age":"20","Sex":"Male","Race":"White","Time":"Day 15"},
"Additional sample data":{"Type":"Plasma","BMI":"20.3","Ethnicity":"NA","RAW_FILE_NAME":"0144_WUG_FARMM_HIL-9003-2-PA.raw;0144_WUG_FARMM_LIP-9003-2-PA.raw;0144_WU_FARMM_CMH_9003-2-PA.raw;0144_WUG_FARMM_FFA-9003-2-PA.raw"}
},
{
"Subject ID":"9003",
"Sample ID":"9003-2-PB",
"Factors":{"Study_Diet":"Modulen","Age":"20","Sex":"Male","Race":"White","Time":"Day 12"},
"Additional sample data":{"Type":"Plasma","BMI":"20.3","Ethnicity":"NA","RAW_FILE_NAME":"0141_WUG_FARMM_HIL-9003-2-PB.raw;0141_WUG_FARMM_LIP-9003-2-PB.raw;0141_WU_FARMM_CMH_9003-2-PB.raw;0141_WUG_FARMM_FFA-9003-2-PB.raw"}
},
{
"Subject ID":"9003",
"Sample ID":"9003-2-PC",
"Factors":{"Study_Diet":"Modulen","Age":"20","Sex":"Male","Race":"White","Time":"Day 9"},
"Additional sample data":{"Type":"Plasma","BMI":"20.3","Ethnicity":"NA","RAW_FILE_NAME":"0143_WUG_FARMM_HIL-9003-2-PC.raw;0143_WUG_FARMM_LIP-9003-2-PC.raw;0143_WU_FARMM_CMH_9003-2-PC.raw;0143_WUG_FARMM_FFA-9003-2-PC.raw"}
},
{
"Subject ID":"9003",
"Sample ID":"9003-2-PD",
"Factors":{"Study_Diet":"Modulen","Age":"20","Sex":"Male","Race":"White","Time":"Day 5"},
"Additional sample data":{"Type":"Plasma","BMI":"20.3","Ethnicity":"NA","RAW_FILE_NAME":"0142_WUG_FARMM_HIL-9003-2-PD.raw;0142_WUG_FARMM_LIP-9003-2-PD.raw;0142_WU_FARMM_CMH_9003-2-PD.raw;0142_WUG_FARMM_FFA-9003-2-PD.raw"}
},
{
"Subject ID":"9003",
"Sample ID":"9003-2-PE",
"Factors":{"Study_Diet":"Modulen","Age":"20","Sex":"Male","Race":"White","Time":"Baseline"},
"Additional sample data":{"Type":"Plasma","BMI":"20.3","Ethnicity":"NA","RAW_FILE_NAME":"0145_WUG_FARMM_HIL-9003-2-PE.raw;0145_WUG_FARMM_LIP-9003-2-PE.raw;0145_WU_FARMM_CMH_9003-2-PE.raw;0145_WUG_FARMM_FFA-9003-2-PE.raw"}
},
{
"Subject ID":"9004",
"Sample ID":"9004-3-PA",
"Factors":{"Study_Diet":"Vegan","Age":"24","Sex":"Male","Race":"White","Time":"Day 15"},
"Additional sample data":{"Type":"Plasma","BMI":"21.7","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0091_WUG_FARMM_HIL-9004-3-PA.raw;0091_WUG_FARMM_LIP-9004-3-PA.raw;0091_WU_FARMM_CMH_9004-3-PA.raw;0091_WUG_FARMM_FFA-9004-3-PA.raw"}
},
{
"Subject ID":"9004",
"Sample ID":"9004-3-PB",
"Factors":{"Study_Diet":"Vegan","Age":"24","Sex":"Male","Race":"White","Time":"Day 12"},
"Additional sample data":{"Type":"Plasma","BMI":"21.7","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0092_WUG_FARMM_HIL-9004-3-PB.raw;0092_WUG_FARMM_LIP-9004-3-PB.raw;0092_WU_FARMM_CMH_9004-3-PB.raw;0092_WUG_FARMM_FFA-9004-3-PB.raw"}
},
{
"Subject ID":"9004",
"Sample ID":"9004-3-PC",
"Factors":{"Study_Diet":"Vegan","Age":"24","Sex":"Male","Race":"White","Time":"Day 9"},
"Additional sample data":{"Type":"Plasma","BMI":"21.7","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0095_WUG_FARMM_HIL-9004-3-PC.raw;0095_WUG_FARMM_LIP-9004-3-PC.raw;0095_WU_FARMM_CMH_9004-3-PC.raw;0095_WUG_FARMM_FFA-9004-3-PC.raw"}
},
{
"Subject ID":"9004",
"Sample ID":"9004-3-PD",
"Factors":{"Study_Diet":"Vegan","Age":"24","Sex":"Male","Race":"White","Time":"Day 5"},
"Additional sample data":{"Type":"Plasma","BMI":"21.7","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0093_WUG_FARMM_HIL-9004-3-PD.raw;0093_WUG_FARMM_LIP-9004-3-PD.raw;0093_WU_FARMM_CMH_9004-3-PD.raw;0093_WUG_FARMM_FFA-9004-3-PD.raw"}
},
{
"Subject ID":"9004",
"Sample ID":"9004-3-PE",
"Factors":{"Study_Diet":"Vegan","Age":"24","Sex":"Male","Race":"White","Time":"Baseline"},
"Additional sample data":{"Type":"Plasma","BMI":"21.7","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0094_WUG_FARMM_HIL-9004-3-PE.raw;0094_WUG_FARMM_LIP-9004-3-PE.raw;0094_WU_FARMM_CMH_9004-3-PE.raw;0094_WUG_FARMM_FFA-9004-3-PE.raw"}
},
{
"Subject ID":"9005",
"Sample ID":"9005-1-PA",
"Factors":{"Study_Diet":"Western","Age":"23","Sex":"Male","Race":"White","Time":"Day 15"},
"Additional sample data":{"Type":"Plasma","BMI":"21.6","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0109_WUG_FARMM_HIL-9005-1-PA.raw;0150d_0109ri_WUG_FARMM_LIP-9005-1-PA.raw;0109_WU_FARMM_CMH_9005-1-PA.raw;0109_WUG_FARMM_FFA-9005-1-PA.raw"}
},
{
"Subject ID":"9005",
"Sample ID":"9005-1-PB",
"Factors":{"Study_Diet":"Western","Age":"23","Sex":"Male","Race":"White","Time":"Day 12"},
"Additional sample data":{"Type":"Plasma","BMI":"21.6","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0106_WUG_FARMM_HIL-9005-1-PB.raw;0106_WUG_FARMM_LIP-9005-1-PB.raw;0106_WU_FARMM_CMH_9005-1-PB.raw;0106_WUG_FARMM_FFA-9005-1-PB.raw"}
},
{
"Subject ID":"9005",
"Sample ID":"9005-1-PC",
"Factors":{"Study_Diet":"Western","Age":"23","Sex":"Male","Race":"White","Time":"Day 9"},
"Additional sample data":{"Type":"Plasma","BMI":"21.6","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0108_WUG_FARMM_HIL-9005-1-PC.raw;0150c_0108ri_WUG_FARMM_LIP-9005-1-PC.raw;0108_WU_FARMM_CMH_9005-1-PC.raw;0108_WUG_FARMM_FFA-9005-1-PC.raw"}
},
{
"Subject ID":"9005",
"Sample ID":"9005-1-PD",
"Factors":{"Study_Diet":"Western","Age":"23","Sex":"Male","Race":"White","Time":"Day 5"},
"Additional sample data":{"Type":"Plasma","BMI":"21.6","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0107_WUG_FARMM_HIL-9005-1-PD.raw;0107_WUG_FARMM_LIP-9005-1-PD.raw;0107_WU_FARMM_CMH_9005-1-PD.raw;0107_WUG_FARMM_FFA-9005-1-PD.raw"}
},
{
"Subject ID":"9005",
"Sample ID":"9005-1-PE",
"Factors":{"Study_Diet":"Western","Age":"23","Sex":"Male","Race":"White","Time":"Baseline"},
"Additional sample data":{"Type":"Plasma","BMI":"21.6","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0110_WUG_FARMM_HIL-9005-1-PE.raw;0150e_0110ri_WUG_FARMM_LIP-9005-1-PE.raw;0110_WU_FARMM_CMH_9005-1-PE.raw;0110_WUG_FARMM_FFA-9005-1-PE.raw"}
},
{
"Subject ID":"9006",
"Sample ID":"9006-1-PA",
"Factors":{"Study_Diet":"Western","Age":"24","Sex":"Male","Race":"White","Time":"Day 15"},
"Additional sample data":{"Type":"Plasma","BMI":"28.2","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0047_WUG_FARMM_HIL-9006-1-PA.raw;0047_WUG_FARMM_LIP-9006-1-PA.raw;0047_WU_FARMM_CMH_9006-1-PA.raw;0047_WUG_FARMM_FFA-9006-1-PA.raw"}
},
{
"Subject ID":"9006",
"Sample ID":"9006-1-PB",
"Factors":{"Study_Diet":"Western","Age":"24","Sex":"Male","Race":"White","Time":"Day 12"},
"Additional sample data":{"Type":"Plasma","BMI":"28.2","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0048_WUG_FARMM_HIL-9006-1-PB.raw;0048_WUG_FARMM_LIP-9006-1-PB.raw;0048_WU_FARMM_CMH_9006-1-PB.raw;0048_WUG_FARMM_FFA-9006-1-PB.raw"}
},
{
"Subject ID":"9006",
"Sample ID":"9006-1-PC",
"Factors":{"Study_Diet":"Western","Age":"24","Sex":"Male","Race":"White","Time":"Day 9"},
"Additional sample data":{"Type":"Plasma","BMI":"28.2","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0050_WUG_FARMM_HIL-9006-1-PC.raw;0050_WUG_FARMM_LIP-9006-1-PC.raw;0050_WU_FARMM_CMH_9006-1-PC.raw;0050_WUG_FARMM_FFA-9006-1-PC.raw"}
},
{
"Subject ID":"9006",
"Sample ID":"9006-1-PD",
"Factors":{"Study_Diet":"Western","Age":"24","Sex":"Male","Race":"White","Time":"Day 5"},
"Additional sample data":{"Type":"Plasma","BMI":"28.2","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0046_WUG_FARMM_HIL-9006-1-PD.raw;0046_WUG_FARMM_LIP-9006-1-PD.raw;0046_WU_FARMM_CMH_9006-1-PD.raw;0046_WUG_FARMM_FFA-9006-1-PD.raw"}
},
{
"Subject ID":"9006",
"Sample ID":"9006-1-PE",
"Factors":{"Study_Diet":"Western","Age":"24","Sex":"Male","Race":"White","Time":"Baseline"},
"Additional sample data":{"Type":"Plasma","BMI":"28.2","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0049_WUG_FARMM_HIL-9006-1-PE.raw;0049_WUG_FARMM_LIP-9006-1-PE.raw;0049_WU_FARMM_CMH_9006-1-PE.raw;0049_WUG_FARMM_FFA-9006-1-PE.raw"}
},
{
"Subject ID":"9008",
"Sample ID":"9008-3-PA",
"Factors":{"Study_Diet":"Vegan","Age":"23","Sex":"Male","Race":"White","Time":"Day 15"},
"Additional sample data":{"Type":"Plasma","BMI":"20","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0103_WUG_FARMM_HIL-9008-3-PA.raw;0103_WUG_FARMM_LIP-9008-3-PA.raw;0103_WU_FARMM_CMH_9008-3-PA.raw;0103_WUG_FARMM_FFA-9008-3-PA.raw"}
},
{
"Subject ID":"9008",
"Sample ID":"9008-3-PB",
"Factors":{"Study_Diet":"Vegan","Age":"23","Sex":"Male","Race":"White","Time":"Day 12"},
"Additional sample data":{"Type":"Plasma","BMI":"20","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0105_WUG_FARMM_HIL-9008-3-PB.raw;0105_WUG_FARMM_LIP-9008-3-PB.raw;0105_WU_FARMM_CMH_9008-3-PB.raw;0105_WUG_FARMM_FFA-9008-3-PB.raw"}
},
{
"Subject ID":"9008",
"Sample ID":"9008-3-PC",
"Factors":{"Study_Diet":"Vegan","Age":"23","Sex":"Male","Race":"White","Time":"Day 9"},
"Additional sample data":{"Type":"Plasma","BMI":"20","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0101_WUG_FARMM_HIL-9008-3-PC.raw;0101_WUG_FARMM_LIP-9008-3-PC.raw;0101_WU_FARMM_CMH_9008-3-PC.raw;0101_WUG_FARMM_FFA-9008-3-PC.raw"}
},
{
"Subject ID":"9008",
"Sample ID":"9008-3-PD",
"Factors":{"Study_Diet":"Vegan","Age":"23","Sex":"Male","Race":"White","Time":"Day 5"},
"Additional sample data":{"Type":"Plasma","BMI":"20","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0104_WUG_FARMM_HIL-9008-3-PD.raw;0104_WUG_FARMM_LIP-9008-3-PD.raw;0104_WU_FARMM_CMH_9008-3-PD.raw;0104_WUG_FARMM_FFA-9008-3-PD.raw"}
},
{
"Subject ID":"9008",
"Sample ID":"9008-3-PE",
"Factors":{"Study_Diet":"Vegan","Age":"23","Sex":"Male","Race":"White","Time":"Baseline"},
"Additional sample data":{"Type":"Plasma","BMI":"20","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0102_WUG_FARMM_HIL-9008-3-PE.raw;0102_WUG_FARMM_LIP-9008-3-PE.raw;0102_WU_FARMM_CMH_9008-3-PE.raw;0102_WUG_FARMM_FFA-9008-3-PE.raw"}
},
{
"Subject ID":"9009",
"Sample ID":"9009-2-PA",
"Factors":{"Study_Diet":"Modulen","Age":"23","Sex":"Male","Race":"White","Time":"Day 15"},
"Additional sample data":{"Type":"Plasma","BMI":"22.4","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0131_WUG_FARMM_HIL-9009-2-PA.raw;0131_WUG_FARMM_LIP-9009-2-PA.raw;0131_WU_FARMM_CMH_9009-2-PA.raw;0131_WUG_FARMM_FFA-9009-2-PA.raw"}
},
{
"Subject ID":"9009",
"Sample ID":"9009-2-PB",
"Factors":{"Study_Diet":"Modulen","Age":"23","Sex":"Male","Race":"White","Time":"Day 12"},
"Additional sample data":{"Type":"Plasma","BMI":"22.4","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0132_WUG_FARMM_HIL-9009-2-PB.raw;0132_WUG_FARMM_LIP-9009-2-PB.raw;0132_WU_FARMM_CMH_9009-2-PB.raw;0132_WUG_FARMM_FFA-9009-2-PB.raw"}
},
{
"Subject ID":"9009",
"Sample ID":"9009-2-PC",
"Factors":{"Study_Diet":"Modulen","Age":"23","Sex":"Male","Race":"White","Time":"Day 9"},
"Additional sample data":{"Type":"Plasma","BMI":"22.4","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0133_WUG_FARMM_HIL-9009-2-PC.raw;0133_WUG_FARMM_LIP-9009-2-PC.raw;0133_WU_FARMM_CMH_9009-2-PC.raw;0133_WUG_FARMM_FFA-9009-2-PC.raw"}
},
{
"Subject ID":"9009",
"Sample ID":"9009-2-PD",
"Factors":{"Study_Diet":"Modulen","Age":"23","Sex":"Male","Race":"White","Time":"Day 5"},
"Additional sample data":{"Type":"Plasma","BMI":"22.4","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0134_WUG_FARMM_HIL-9009-2-PD.raw;0134_WUG_FARMM_LIP-9009-2-PD.raw;0134_WU_FARMM_CMH_9009-2-PD.raw;0134_WUG_FARMM_FFA-9009-2-PD.raw"}
},
{
"Subject ID":"9009",
"Sample ID":"9009-2-PE",
"Factors":{"Study_Diet":"Modulen","Age":"23","Sex":"Male","Race":"White","Time":"Baseline"},
"Additional sample data":{"Type":"Plasma","BMI":"22.4","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0135_WUG_FARMM_HIL-9009-2-PE.raw;0135_WUG_FARMM_LIP-9009-2-PE.raw;0135_WU_FARMM_CMH_9009-2-PE.raw;0135_WUG_FARMM_FFA-9009-2-PE.raw"}
},
{
"Subject ID":"9010",
"Sample ID":"9010-1-PA",
"Factors":{"Study_Diet":"Western","Age":"24","Sex":"Female","Race":"White","Time":"Day 15"},
"Additional sample data":{"Type":"Plasma","BMI":"21.8","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0149_WUG_FARMM_HIL-9010-1-PA.raw;0149_WUG_FARMM_LIP-9010-1-PA.raw;0149_WU_FARMM_CMH_9010-1-PA.raw;0149_WUG_FARMM_FFA-9010-1-PA.raw"}
},
{
"Subject ID":"9010",
"Sample ID":"9010-1-PB",
"Factors":{"Study_Diet":"Western","Age":"24","Sex":"Female","Race":"White","Time":"Day 12"},
"Additional sample data":{"Type":"Plasma","BMI":"21.8","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0148_WUG_FARMM_HIL-9010-1-PB.raw;0148_WUG_FARMM_LIP-9010-1-PB.raw;0148_WU_FARMM_CMH_9010-1-PB.raw;0148_WUG_FARMM_FFA-9010-1-PB.raw"}
},
{
"Subject ID":"9010",
"Sample ID":"9010-1-PC",
"Factors":{"Study_Diet":"Western","Age":"24","Sex":"Female","Race":"White","Time":"Day 9"},
"Additional sample data":{"Type":"Plasma","BMI":"21.8","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0147_WUG_FARMM_HIL-9010-1-PC.raw;0147_WUG_FARMM_LIP-9010-1-PC.raw;0147_WU_FARMM_CMH_9010-1-PC.raw;0147_WUG_FARMM_FFA-9010-1-PC.raw"}
},
{
"Subject ID":"9010",
"Sample ID":"9010-1-PD",
"Factors":{"Study_Diet":"Western","Age":"24","Sex":"Female","Race":"White","Time":"Day 5"},
"Additional sample data":{"Type":"Plasma","BMI":"21.8","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0146_WUG_FARMM_HIL-9010-1-PD.raw;0146_WUG_FARMM_LIP-9010-1-PD.raw;0146_WU_FARMM_CMH_9010-1-PD.raw;0146_WUG_FARMM_FFA-9010-1-PD.raw"}
},
{
"Subject ID":"9010",
"Sample ID":"9010-1-PE",
"Factors":{"Study_Diet":"Western","Age":"24","Sex":"Female","Race":"White","Time":"Baseline"},
"Additional sample data":{"Type":"Plasma","BMI":"21.8","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0150_WUG_FARMM_HIL-9010-1-PE.raw;0150_WUG_FARMM_LIP-9010-1-PE.raw;0150_WU_FARMM_CMH_9010-1-PE.raw;0150_WUG_FARMM_FFA-9010-1-PE.raw"}
},
{
"Subject ID":"9013",
"Sample ID":"9013-2-PA",
"Factors":{"Study_Diet":"Modulen","Age":"40","Sex":"Male","Race":"White","Time":"Day 15"},
"Additional sample data":{"Type":"Plasma","BMI":"24.1","Ethnicity":"Hispanic or Latino","RAW_FILE_NAME":"0075_WUG_FARMM_HIL-9013-2-PA.raw;0075_WUG_FARMM_LIP-9013-2-PA.raw;0075_WU_FARMM_CMH_9013-2-PA.raw;0075_WUG_FARMM_FFA-9013-2-PA.raw"}
},
{
"Subject ID":"9013",
"Sample ID":"9013-2-PB",
"Factors":{"Study_Diet":"Modulen","Age":"40","Sex":"Male","Race":"White","Time":"Day 12"},
"Additional sample data":{"Type":"Plasma","BMI":"24.1","Ethnicity":"Hispanic or Latino","RAW_FILE_NAME":"0074_WUG_FARMM_HIL-9013-2-PB.raw;0074_WUG_FARMM_LIP-9013-2-PB.raw;0074_WU_FARMM_CMH_9013-2-PB.raw;0074_WUG_FARMM_FFA-9013-2-PB.raw"}
},
{
"Subject ID":"9013",
"Sample ID":"9013-2-PC",
"Factors":{"Study_Diet":"Modulen","Age":"40","Sex":"Male","Race":"White","Time":"Day 9"},
"Additional sample data":{"Type":"Plasma","BMI":"24.1","Ethnicity":"Hispanic or Latino","RAW_FILE_NAME":"0072_WUG_FARMM_HIL-9013-2-PC.raw;0072_WUG_FARMM_LIP-9013-2-PC.raw;0072_WU_FARMM_CMH_9013-2-PC.raw;0072_WUG_FARMM_FFA-9013-2-PC.raw"}
},
{
"Subject ID":"9013",
"Sample ID":"9013-2-PD",
"Factors":{"Study_Diet":"Modulen","Age":"40","Sex":"Male","Race":"White","Time":"Day 5"},
"Additional sample data":{"Type":"Plasma","BMI":"24.1","Ethnicity":"Hispanic or Latino","RAW_FILE_NAME":"0071_WUG_FARMM_HIL-9013-2-PD.raw;0071_WUG_FARMM_LIP-9013-2-PD.raw;0071_WU_FARMM_CMH_9013-2-PD.raw;0071_WUG_FARMM_FFA-9013-2-PD.raw"}
},
{
"Subject ID":"9013",
"Sample ID":"9013-2-PE",
"Factors":{"Study_Diet":"Modulen","Age":"40","Sex":"Male","Race":"White","Time":"Baseline"},
"Additional sample data":{"Type":"Plasma","BMI":"24.1","Ethnicity":"Hispanic or Latino","RAW_FILE_NAME":"0073_WUG_FARMM_HIL-9013-2-PE.raw;0073_WUG_FARMM_LIP-9013-2-PE.raw;0073_WU_FARMM_CMH_9013-2-PE.raw;0073_WUG_FARMM_FFA-9013-2-PE.raw"}
},
{
"Subject ID":"9014",
"Sample ID":"9014-3-PA",
"Factors":{"Study_Diet":"Vegan","Age":"23","Sex":"Female","Race":"White","Time":"Day 15"},
"Additional sample data":{"Type":"Plasma","BMI":"20.9","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0010_WUG_FARMM_HIL-9014-3-PA.raw;0010_WUG_FARMM_LIP-9014-3-PA.raw;0010_WU_FARMM_CMH_9014-3-PA.raw;0010_WUG_FARMM_FFA-9014-3-PA.raw"}
},
{
"Subject ID":"9014",
"Sample ID":"9014-3-PB",
"Factors":{"Study_Diet":"Vegan","Age":"23","Sex":"Female","Race":"White","Time":"Day 12"},
"Additional sample data":{"Type":"Plasma","BMI":"20.9","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0008_WUG_FARMM_HIL-9014-3-PB.raw;0008_WUG_FARMM_LIP-9014-3-PB.raw;0008_WU_FARMM_CMH_9014-3-PB.raw;0008_WUG_FARMM_FFA-9014-3-PB.raw"}
},
{
"Subject ID":"9014",
"Sample ID":"9014-3-PC",
"Factors":{"Study_Diet":"Vegan","Age":"23","Sex":"Female","Race":"White","Time":"Day 9"},
"Additional sample data":{"Type":"Plasma","BMI":"20.9","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0006_WUG_FARMM_HIL-9014-3-PC.raw;0006_WUG_FARMM_LIP-9014-3-PC.raw;0006_WU_FARMM_CMH_9014-3-PC.raw;0006_WUG_FARMM_FFA-9014-3-PC.raw"}
},
{
"Subject ID":"9014",
"Sample ID":"9014-3-PD",
"Factors":{"Study_Diet":"Vegan","Age":"23","Sex":"Female","Race":"White","Time":"Day 5"},
"Additional sample data":{"Type":"Plasma","BMI":"20.9","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0009_WUG_FARMM_HIL-9014-3-PD.raw;0009_WUG_FARMM_LIP-9014-3-PD.raw;0009_WU_FARMM_CMH_9014-3-PD.raw;0009_WUG_FARMM_FFA-9014-3-PD.raw"}
},
{
"Subject ID":"9014",
"Sample ID":"9014-3-PE",
"Factors":{"Study_Diet":"Vegan","Age":"23","Sex":"Female","Race":"White","Time":"Baseline"},
"Additional sample data":{"Type":"Plasma","BMI":"20.9","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0007_WUG_FARMM_HIL-9014-3-PE.raw;0007_WUG_FARMM_LIP-9014-3-PE.raw;0007_WU_FARMM_CMH_9014-3-PE.raw;0007_WUG_FARMM_FFA-9014-3-PE.raw"}
},
{
"Subject ID":"9015",
"Sample ID":"9015-1-PA",
"Factors":{"Study_Diet":"Western","Age":"23","Sex":"Female","Race":"White","Time":"Day 15"},
"Additional sample data":{"Type":"Plasma","BMI":"20.5","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0097_WUG_FARMM_HIL-9015-1-PA.raw;0097_WUG_FARMM_LIP-9015-1-PA.raw;0097_WU_FARMM_CMH_9015-1-PA.raw;0097_WUG_FARMM_FFA-9015-1-PA.raw"}
},
{
"Subject ID":"9015",
"Sample ID":"9015-1-PB",
"Factors":{"Study_Diet":"Western","Age":"23","Sex":"Female","Race":"White","Time":"Day 12"},
"Additional sample data":{"Type":"Plasma","BMI":"20.5","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0096_WUG_FARMM_HIL-9015-1-PB.raw;0096_WUG_FARMM_LIP-9015-1-PB.raw;0096_WU_FARMM_CMH_9015-1-PB.raw;0096_WUG_FARMM_FFA-9015-1-PB.raw"}
},
{
"Subject ID":"9015",
"Sample ID":"9015-1-PC",
"Factors":{"Study_Diet":"Western","Age":"23","Sex":"Female","Race":"White","Time":"Day 9"},
"Additional sample data":{"Type":"Plasma","BMI":"20.5","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0100_WUG_FARMM_HIL-9015-1-PC.raw;0100_WUG_FARMM_LIP-9015-1-PC.raw;0100_WU_FARMM_CMH_9015-1-PC.raw;0100_WUG_FARMM_FFA-9015-1-PC.raw"}
},
{
"Subject ID":"9015",
"Sample ID":"9015-1-PD",
"Factors":{"Study_Diet":"Western","Age":"23","Sex":"Female","Race":"White","Time":"Day 5"},
"Additional sample data":{"Type":"Plasma","BMI":"20.5","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0099_WUG_FARMM_HIL-9015-1-PD.raw;0099_WUG_FARMM_LIP-9015-1-PD.raw;0099_WU_FARMM_CMH_9015-1-PD.raw;0099_WUG_FARMM_FFA-9015-1-PD.raw"}
},
{
"Subject ID":"9015",
"Sample ID":"9015-1-PE",
"Factors":{"Study_Diet":"Western","Age":"23","Sex":"Female","Race":"White","Time":"Baseline"},
"Additional sample data":{"Type":"Plasma","BMI":"20.5","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0098_WUG_FARMM_HIL-9015-1-PE.raw;0098_WUG_FARMM_LIP-9015-1-PE.raw;0098_WU_FARMM_CMH_9015-1-PE.raw;0098_WUG_FARMM_FFA-9015-1-PE.raw"}
},
{
"Subject ID":"9016",
"Sample ID":"9016-2-PA",
"Factors":{"Study_Diet":"Modulen","Age":"38","Sex":"Female","Race":"White","Time":"Day 15"},
"Additional sample data":{"Type":"Plasma","BMI":"25.6","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0067_WUG_FARMM_HIL-9016-2-PA.raw;0067_WUG_FARMM_LIP-9016-2-PA.raw;0067_WU_FARMM_CMH_9016-2-PA.raw;0067_WUG_FARMM_FFA-9016-2-PA.raw"}
},
{
"Subject ID":"9016",
"Sample ID":"9016-2-PB",
"Factors":{"Study_Diet":"Modulen","Age":"38","Sex":"Female","Race":"White","Time":"Day 12"},
"Additional sample data":{"Type":"Plasma","BMI":"25.6","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0066_WUG_FARMM_HIL-9016-2-PB.raw;0066_WUG_FARMM_LIP-9016-2-PB.raw;0066_WU_FARMM_CMH_9016-2-PB.raw;0066_WUG_FARMM_FFA-9016-2-PB.raw"}
},
{
"Subject ID":"9016",
"Sample ID":"9016-2-PC",
"Factors":{"Study_Diet":"Modulen","Age":"38","Sex":"Female","Race":"White","Time":"Day 9"},
"Additional sample data":{"Type":"Plasma","BMI":"25.6","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0070_WUG_FARMM_HIL-9016-2-PC.raw;0070_WUG_FARMM_LIP-9016-2-PC.raw;0070_WU_FARMM_CMH_9016-2-PC.raw;0070_WUG_FARMM_FFA-9016-2-PC.raw"}
},
{
"Subject ID":"9016",
"Sample ID":"9016-2-PD",
"Factors":{"Study_Diet":"Modulen","Age":"38","Sex":"Female","Race":"White","Time":"Day 5"},
"Additional sample data":{"Type":"Plasma","BMI":"25.6","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0068_WUG_FARMM_HIL-9016-2-PD.raw;0068_WUG_FARMM_LIP-9016-2-PD.raw;0068_WU_FARMM_CMH_9016-2-PD.raw;0068_WUG_FARMM_FFA-9016-2-PD.raw"}
},
{
"Subject ID":"9016",
"Sample ID":"9016-2-PE",
"Factors":{"Study_Diet":"Modulen","Age":"38","Sex":"Female","Race":"White","Time":"Baseline"},
"Additional sample data":{"Type":"Plasma","BMI":"25.6","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0069_WUG_FARMM_HIL-9016-2-PE.raw;0069_WUG_FARMM_LIP-9016-2-PE.raw;0069_WU_FARMM_CMH_9016-2-PE.raw;0069_WUG_FARMM_FFA-9016-2-PE.raw"}
},
{
"Subject ID":"9017",
"Sample ID":"9017-3-PA",
"Factors":{"Study_Diet":"Vegan","Age":"25","Sex":"Male","Race":"White","Time":"Day 15"},
"Additional sample data":{"Type":"Plasma","BMI":"20.6","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0057_WUG_FARMM_HIL-9017-3-PA.raw;0057_WUG_FARMM_LIP-9017-3-PA.raw;0057_WU_FARMM_CMH_9017-3-PA.raw;0057_WUG_FARMM_FFA-9017-3-PA.raw"}
},
{
"Subject ID":"9017",
"Sample ID":"9017-3-PB",
"Factors":{"Study_Diet":"Vegan","Age":"25","Sex":"Male","Race":"White","Time":"Day 12"},
"Additional sample data":{"Type":"Plasma","BMI":"20.6","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0056_WUG_FARMM_HIL-9017-3-PB.raw;0056_WUG_FARMM_LIP-9017-3-PB.raw;0056_WU_FARMM_CMH_9017-3-PB.raw;0056_WUG_FARMM_FFA-9017-3-PB.raw"}
},
{
"Subject ID":"9017",
"Sample ID":"9017-3-PC",
"Factors":{"Study_Diet":"Vegan","Age":"25","Sex":"Male","Race":"White","Time":"Day 9"},
"Additional sample data":{"Type":"Plasma","BMI":"20.6","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0058_WUG_FARMM_HIL-9017-3-PC.raw;0058_WUG_FARMM_LIP-9017-3-PC.raw;0058_WU_FARMM_CMH_9017-3-PC.raw;0058_WUG_FARMM_FFA-9017-3-PC.raw"}
},
{
"Subject ID":"9017",
"Sample ID":"9017-3-PD",
"Factors":{"Study_Diet":"Vegan","Age":"25","Sex":"Male","Race":"White","Time":"Day 5"},
"Additional sample data":{"Type":"Plasma","BMI":"20.6","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0060_WUG_FARMM_HIL-9017-3-PD.raw;0060_WUG_FARMM_LIP-9017-3-PD.raw;0060_WU_FARMM_CMH_9017-3-PD.raw;0060_WUG_FARMM_FFA-9017-3-PD.raw"}
},
{
"Subject ID":"9017",
"Sample ID":"9017-3-PE",
"Factors":{"Study_Diet":"Vegan","Age":"25","Sex":"Male","Race":"White","Time":"Baseline"},
"Additional sample data":{"Type":"Plasma","BMI":"20.6","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0059_WUG_FARMM_HIL-9017-3-PE.raw;0059_WUG_FARMM_LIP-9017-3-PE.raw;0059_WU_FARMM_CMH_9017-3-PE.raw;0059_WUG_FARMM_FFA-9017-3-PE.raw"}
},
{
"Subject ID":"9019",
"Sample ID":"9019-1-PA",
"Factors":{"Study_Diet":"Western","Age":"36","Sex":"Male","Race":"Black/African American","Time":"Day 15"},
"Additional sample data":{"Type":"Plasma","BMI":"21.8","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0061_WUG_FARMM_HIL-9019-1-PA.raw;0061_WUG_FARMM_LIP-9019-1-PA.raw;0061_WU_FARMM_CMH_9019-1-PA.raw;0061_WUG_FARMM_FFA-9019-1-PA.raw"}
},
{
"Subject ID":"9019",
"Sample ID":"9019-1-PB",
"Factors":{"Study_Diet":"Western","Age":"36","Sex":"Male","Race":"Black/African American","Time":"Day 12"},
"Additional sample data":{"Type":"Plasma","BMI":"21.8","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0063_WUG_FARMM_HIL-9019-1-PB.raw;0063_WUG_FARMM_LIP-9019-1-PB.raw;0063_WU_FARMM_CMH_9019-1-PB.raw;0063_WUG_FARMM_FFA-9019-1-PB.raw"}
},
{
"Subject ID":"9019",
"Sample ID":"9019-1-PC",
"Factors":{"Study_Diet":"Western","Age":"36","Sex":"Male","Race":"Black/African American","Time":"Day 9"},
"Additional sample data":{"Type":"Plasma","BMI":"21.8","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0064_WUG_FARMM_HIL-9019-1-PC.raw;0064_WUG_FARMM_LIP-9019-1-PC.raw;0064_WU_FARMM_CMH_9019-1-PC.raw;0064_WUG_FARMM_FFA-9019-1-PC.raw"}
},
{
"Subject ID":"9019",
"Sample ID":"9019-1-PD",
"Factors":{"Study_Diet":"Western","Age":"36","Sex":"Male","Race":"Black/African American","Time":"Day 5"},
"Additional sample data":{"Type":"Plasma","BMI":"21.8","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0062_WUG_FARMM_HIL-9019-1-PD.raw;0062_WUG_FARMM_LIP-9019-1-PD.raw;0062_WU_FARMM_CMH_9019-1-PD.raw;0062_WUG_FARMM_FFA-9019-1-PD.raw"}
},
{
"Subject ID":"9019",
"Sample ID":"9019-1-PE",
"Factors":{"Study_Diet":"Western","Age":"36","Sex":"Male","Race":"Black/African American","Time":"Baseline"},
"Additional sample data":{"Type":"Plasma","BMI":"21.8","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0065_WUG_FARMM_HIL-9019-1-PE.raw;0065_WUG_FARMM_LIP-9019-1-PE.raw;0065_WU_FARMM_CMH_9019-1-PE.raw;0065_WUG_FARMM_FFA-9019-1-PE.raw"}
},
{
"Subject ID":"9022",
"Sample ID":"9022-3-PA",
"Factors":{"Study_Diet":"Vegan","Age":"25","Sex":"Male","Race":"White","Time":"Day 15"},
"Additional sample data":{"Type":"Plasma","BMI":"21.8","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0005_WUG_FARMM_HIL-9022-3-PA.raw;0005_WUG_FARMM_LIP-9022-3-PA.raw;0005_WU_FARMM_CMH_9022-3-PA.raw;0005_WUG_FARMM_FFA-9022-3-PA.raw"}
},
{
"Subject ID":"9022",
"Sample ID":"9022-3-PB",
"Factors":{"Study_Diet":"Vegan","Age":"25","Sex":"Male","Race":"White","Time":"Day 12"},
"Additional sample data":{"Type":"Plasma","BMI":"21.8","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0003_WUG_FARMM_HIL-9022-3-PB.raw;0003_WUG_FARMM_LIP-9022-3-PB.raw;0003_WU_FARMM_CMH_9022-3-PB.raw;0003_WUG_FARMM_FFA-9022-3-PB.raw"}
},
{
"Subject ID":"9022",
"Sample ID":"9022-3-PC",
"Factors":{"Study_Diet":"Vegan","Age":"25","Sex":"Male","Race":"White","Time":"Day 9"},
"Additional sample data":{"Type":"Plasma","BMI":"21.8","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0004_WUG_FARMM_HIL-9022-3-PC.raw;0004_WUG_FARMM_LIP-9022-3-PC.raw;0004_WU_FARMM_CMH_9022-3-PC.raw;0004_WUG_FARMM_FFA-9022-3-PC.raw"}
},
{
"Subject ID":"9022",
"Sample ID":"9022-3-PD",
"Factors":{"Study_Diet":"Vegan","Age":"25","Sex":"Male","Race":"White","Time":"Day 5"},
"Additional sample data":{"Type":"Plasma","BMI":"21.8","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0002_WUG_FARMM_HIL-9022-3-PD.raw;0002_WUG_FARMM_LIP-9022-3-PD.raw;0002_WU_FARMM_CMH_9022-3-PD.raw;0002_WUG_FARMM_FFA-9022-3-PD.raw"}
},
{
"Subject ID":"9022",
"Sample ID":"9022-3-PE",
"Factors":{"Study_Diet":"Vegan","Age":"25","Sex":"Male","Race":"White","Time":"Baseline"},
"Additional sample data":{"Type":"Plasma","BMI":"21.8","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0001_WUG_FARMM_HIL-9022-3.raw;0001_WUG_FARMM_LIP-9022-3-PE.raw;0001_WU_FARMM_CMH_9022-3-PE.raw;0001_WUG_FARMM_FFA-9022-3-PE.raw"}
},
{
"Subject ID":"9024",
"Sample ID":"9024-2-PA",
"Factors":{"Study_Diet":"Modulen","Age":"27","Sex":"Female","Race":"Black/African American","Time":"Day 15"},
"Additional sample data":{"Type":"Plasma","BMI":"34.6","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0012_WUG_FARMM_HIL-9024-2-PA.raw;0012_WUG_FARMM_LIP-9024-2-PA.raw;0012_WU_FARMM_CMH_9024-2-PA.raw;0012_WUG_FARMM_FFA-9024-2-PA.raw"}
},
{
"Subject ID":"9024",
"Sample ID":"9024-2-PB",
"Factors":{"Study_Diet":"Modulen","Age":"27","Sex":"Female","Race":"Black/African American","Time":"Day 12"},
"Additional sample data":{"Type":"Plasma","BMI":"34.6","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0013_WUG_FARMM_HIL-9024-2-PB.raw;0013_WUG_FARMM_LIP-9024-2-PB.raw;0013_WU_FARMM_CMH_9024-2-PB.raw;0013_WUG_FARMM_FFA-9024-2-PB.raw"}
},
{
"Subject ID":"9024",
"Sample ID":"9024-2-PC",
"Factors":{"Study_Diet":"Modulen","Age":"27","Sex":"Female","Race":"Black/African American","Time":"Day 9"},
"Additional sample data":{"Type":"Plasma","BMI":"34.6","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0015_WUG_FARMM_HIL-9024-2-PC.raw;0015_WUG_FARMM_LIP-9024-2-PC.raw;0015_WU_FARMM_CMH_9024-2-PC.raw;0015_WUG_FARMM_FFA-9024-2-PC.raw"}
},
{
"Subject ID":"9024",
"Sample ID":"9024-2-PD",
"Factors":{"Study_Diet":"Modulen","Age":"27","Sex":"Female","Race":"Black/African American","Time":"Day 5"},
"Additional sample data":{"Type":"Plasma","BMI":"34.6","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0014_WUG_FARMM_HIL-9024-2-PD.raw;0014_WUG_FARMM_LIP-9024-2-PD.raw;0014_WU_FARMM_CMH_9024-2-PD.raw;0014_WUG_FARMM_FFA-9024-2-PD.raw"}
},
{
"Subject ID":"9024",
"Sample ID":"9024-2-PE",
"Factors":{"Study_Diet":"Modulen","Age":"27","Sex":"Female","Race":"Black/African American","Time":"Baseline"},
"Additional sample data":{"Type":"Plasma","BMI":"34.6","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0011_WUG_FARMM_HIL-9024-2-PE.raw;0011_WUG_FARMM_LIP-9024-2-PE.raw;0011_WU_FARMM_CMH_9024-2-PE.raw;0011_WUG_FARMM_FFA-9024-2-PE.raw"}
},
{
"Subject ID":"9025",
"Sample ID":"9025-2-PA",
"Factors":{"Study_Diet":"Modulen","Age":"28","Sex":"Male","Race":"Black/African American","Time":"Day 15"},
"Additional sample data":{"Type":"Plasma","BMI":"30.8","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0041_WUG_FARMM_HIL-9025-2-PA.raw;0041_WUG_FARMM_LIP-9025-2-PA.raw;0041_WU_FARMM_CMH_9025-2-PA.raw;0041_WUG_FARMM_FFA-9025-2-PA.raw"}
},
{
"Subject ID":"9025",
"Sample ID":"9025-2-PB",
"Factors":{"Study_Diet":"Modulen","Age":"28","Sex":"Male","Race":"Black/African American","Time":"Day 12"},
"Additional sample data":{"Type":"Plasma","BMI":"30.8","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0045_WUG_FARMM_HIL-9025-2-PB.raw;0045_WUG_FARMM_LIP-9025-2-PB.raw;0045_WU_FARMM_CMH_9025-2-PB.raw;0045_WUG_FARMM_FFA-9025-2-PB.raw"}
},
{
"Subject ID":"9025",
"Sample ID":"9025-2-PC",
"Factors":{"Study_Diet":"Modulen","Age":"28","Sex":"Male","Race":"Black/African American","Time":"Day 9"},
"Additional sample data":{"Type":"Plasma","BMI":"30.8","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0043_WUG_FARMM_HIL-9025-2-PC.raw;0043_WUG_FARMM_LIP-9025-2-PC.raw;0043_WU_FARMM_CMH_9025-2-PC.raw;0043_WUG_FARMM_FFA-9025-2-PC.raw"}
},
{
"Subject ID":"9025",
"Sample ID":"9025-2-PD",
"Factors":{"Study_Diet":"Modulen","Age":"28","Sex":"Male","Race":"Black/African American","Time":"Day 5"},
"Additional sample data":{"Type":"Plasma","BMI":"30.8","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0044_WUG_FARMM_HIL-9025-2-PD.raw;0044_WUG_FARMM_LIP-9025-2-PD.raw;0044_WU_FARMM_CMH_9025-2-PD.raw;0044_WUG_FARMM_FFA-9025-2-PD.raw"}
},
{
"Subject ID":"9025",
"Sample ID":"9025-2-PE",
"Factors":{"Study_Diet":"Modulen","Age":"28","Sex":"Male","Race":"Black/African American","Time":"Baseline"},
"Additional sample data":{"Type":"Plasma","BMI":"30.8","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0042_WUG_FARMM_HIL-9025-2-PE.raw;0042_WUG_FARMM_LIP-9025-2-PE.raw;0042_WU_FARMM_CMH_9025-2-PE.raw;0042_WUG_FARMM_FFA-9025-2-PE.raw"}
},
{
"Subject ID":"9026",
"Sample ID":"9026-3-PA",
"Factors":{"Study_Diet":"Vegan","Age":"24","Sex":"Female","Race":"Black/African American","Time":"Day 15"},
"Additional sample data":{"Type":"Plasma","BMI":"21.3","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0039_WUG_FARMM_HIL-9026-3-PA.raw;0039_WUG_FARMM_LIP-9026-3-PA.raw;0039_WU_FARMM_CMH_9026-3-PA.raw;0039_WUG_FARMM_FFA-9026-3-PA.raw"}
},
{
"Subject ID":"9026",
"Sample ID":"9026-3-PB",
"Factors":{"Study_Diet":"Vegan","Age":"24","Sex":"Female","Race":"Black/African American","Time":"Day 12"},
"Additional sample data":{"Type":"Plasma","BMI":"21.3","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0040_WUG_FARMM_HIL-9026-3-PB.raw;0040_WUG_FARMM_LIP-9026-3-PB.raw;0040_WU_FARMM_CMH_9026-3-PB.raw;0040_WUG_FARMM_FFA-9026-3-PB.raw"}
},
{
"Subject ID":"9026",
"Sample ID":"9026-3-PC",
"Factors":{"Study_Diet":"Vegan","Age":"24","Sex":"Female","Race":"Black/African American","Time":"Day 9"},
"Additional sample data":{"Type":"Plasma","BMI":"21.3","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0038_WUG_FARMM_HIL-9026-3-PC.raw;0038_WUG_FARMM_LIP-9026-3-PC.raw;0038_WU_FARMM_CMH_9026-3-PC.raw;0038_WUG_FARMM_FFA-9026-3-PC.raw"}
},
{
"Subject ID":"9026",
"Sample ID":"9026-3-PD",
"Factors":{"Study_Diet":"Vegan","Age":"24","Sex":"Female","Race":"Black/African American","Time":"Day 5"},
"Additional sample data":{"Type":"Plasma","BMI":"21.3","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0036_WUG_FARMM_HIL-9026-3-PD.raw;0036_WUG_FARMM_LIP-9026-3-PD.raw;0036_WU_FARMM_CMH_9026-3-PD.raw;0036_WUG_FARMM_FFA-9026-3-PD.raw"}
},
{
"Subject ID":"9026",
"Sample ID":"9026-3-PE",
"Factors":{"Study_Diet":"Vegan","Age":"24","Sex":"Female","Race":"Black/African American","Time":"Baseline"},
"Additional sample data":{"Type":"Plasma","BMI":"21.3","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0037_WUG_FARMM_HIL-9026-3-PE.raw;0037_WUG_FARMM_LIP-9026-3-PE.raw;0037_WU_FARMM_CMH_9026-3-PE.raw;0037_WUG_FARMM_FFA-9026-3-PE.raw"}
},
{
"Subject ID":"9027",
"Sample ID":"9027-3-PA",
"Factors":{"Study_Diet":"Vegan","Age":"22","Sex":"Female","Race":"White","Time":"Day 15"},
"Additional sample data":{"Type":"Plasma","BMI":"25.1","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0030_WUG_FARMM_HIL-9027-3-PA.raw;0030_WUG_FARMM_LIP-9027-3-PA.raw;0030_WU_FARMM_CMH_9027-3-PA.raw;0030_WUG_FARMM_FFA-9027-3-PA.raw"}
},
{
"Subject ID":"9027",
"Sample ID":"9027-3-PB",
"Factors":{"Study_Diet":"Vegan","Age":"22","Sex":"Female","Race":"White","Time":"Day 12"},
"Additional sample data":{"Type":"Plasma","BMI":"25.1","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0028_WUG_FARMM_HIL-9027-3-PB.raw;0028_WUG_FARMM_LIP-9027-3-PB.raw;0028_WU_FARMM_CMH_9027-3-PB.raw;0028_WUG_FARMM_FFA-9027-3-PB.raw"}
},
{
"Subject ID":"9027",
"Sample ID":"9027-3-PC",
"Factors":{"Study_Diet":"Vegan","Age":"22","Sex":"Female","Race":"White","Time":"Day 9"},
"Additional sample data":{"Type":"Plasma","BMI":"25.1","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0029_WUG_FARMM_HIL-9027-3-PC.raw;0029_WUG_FARMM_LIP-9027-3-PC.raw;0029_WU_FARMM_CMH_9027-3-PC.raw;0029_WUG_FARMM_FFA-9027-3-PC.raw"}
},
{
"Subject ID":"9027",
"Sample ID":"9027-3-PD",
"Factors":{"Study_Diet":"Vegan","Age":"22","Sex":"Female","Race":"White","Time":"Day 5"},
"Additional sample data":{"Type":"Plasma","BMI":"25.1","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0026_WUG_FARMM_HIL-9027-3-PD.raw;0026_WUG_FARMM_LIP-9027-3-PD.raw;0026_WU_FARMM_CMH_9027-3-PD.raw;0026_WUG_FARMM_FFA-9027-3-PD.raw"}
},
{
"Subject ID":"9027",
"Sample ID":"9027-3-PE",
"Factors":{"Study_Diet":"Vegan","Age":"22","Sex":"Female","Race":"White","Time":"Baseline"},
"Additional sample data":{"Type":"Plasma","BMI":"25.1","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0027_WUG_FARMM_HIL-9027-3-PE.raw;0027_WUG_FARMM_LIP-9027-3-PE.raw;0027_WU_FARMM_CMH_9027-3-PE.raw;0027_WUG_FARMM_FFA-9027-3-PE.raw"}
},
{
"Subject ID":"9029",
"Sample ID":"9029-2-PA",
"Factors":{"Study_Diet":"Modulen","Age":"26","Sex":"Male","Race":"White","Time":"Day 15"},
"Additional sample data":{"Type":"Plasma","BMI":"35.4","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0128_WUG_FARMM_HIL-9029-2-PA.raw;0128_WUG_FARMM_LIP-9029-2-PA.raw;0128_WU_FARMM_CMH_9029-2-PA.raw;0128_WUG_FARMM_FFA-9029-2-PA.raw"}
},
{
"Subject ID":"9029",
"Sample ID":"9029-2-PB",
"Factors":{"Study_Diet":"Modulen","Age":"26","Sex":"Male","Race":"White","Time":"Day 12"},
"Additional sample data":{"Type":"Plasma","BMI":"35.4","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0126_WUG_FARMM_HIL-9029-2-PB.raw;0126_WUG_FARMM_LIP-9029-2-PB.raw;0126_WU_FARMM_CMH_9029-2-PB.raw;0126_WUG_FARMM_FFA-9029-2-PB.raw"}
},
{
"Subject ID":"9029",
"Sample ID":"9029-2-PC",
"Factors":{"Study_Diet":"Modulen","Age":"26","Sex":"Male","Race":"White","Time":"Day 9"},
"Additional sample data":{"Type":"Plasma","BMI":"35.4","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0130_WUG_FARMM_HIL-9029-2-PC.raw;0130_WUG_FARMM_LIP-9029-2-PC.raw;0130_WU_FARMM_CMH_9029-2-PC.raw;0130_WUG_FARMM_FFA-9029-2-PC.raw"}
},
{
"Subject ID":"9029",
"Sample ID":"9029-2-PD",
"Factors":{"Study_Diet":"Modulen","Age":"26","Sex":"Male","Race":"White","Time":"Day 5"},
"Additional sample data":{"Type":"Plasma","BMI":"35.4","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0127_WUG_FARMM_HIL-9029-2-PD.raw;0127_WUG_FARMM_LIP-9029-2-PD.raw;0127_WU_FARMM_CMH_9029-2-PD.raw;0127_WUG_FARMM_FFA-9029-2-PD.raw"}
},
{
"Subject ID":"9029",
"Sample ID":"9029-2-PE",
"Factors":{"Study_Diet":"Modulen","Age":"26","Sex":"Male","Race":"White","Time":"Baseline"},
"Additional sample data":{"Type":"Plasma","BMI":"35.4","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0129_WUG_FARMM_HIL-9029-2-PE.raw;0129_WUG_FARMM_LIP-9029-2-PE.raw;0129_WU_FARMM_CMH_9029-2-PE.raw;0129_WUG_FARMM_FFA-9029-2-PE.raw"}
},
{
"Subject ID":"9030",
"Sample ID":"9030-1-PA",
"Factors":{"Study_Diet":"Western","Age":"46","Sex":"Male","Race":"White","Time":"Day 15"},
"Additional sample data":{"Type":"Plasma","BMI":"27.7","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0053_WUG_FARMM_HIL-9030-1-PA.raw;0053_WUG_FARMM_LIP-9030-1-PA.raw;0053_WU_FARMM_CMH_9030-1-PA.raw;0053_WUG_FARMM_FFA-9030-1-PA.raw"}
},
{
"Subject ID":"9030",
"Sample ID":"9030-1-PB",
"Factors":{"Study_Diet":"Western","Age":"46","Sex":"Male","Race":"White","Time":"Day 12"},
"Additional sample data":{"Type":"Plasma","BMI":"27.7","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0054_WUG_FARMM_HIL-9030-1-PB.raw;0054_WUG_FARMM_LIP-9030-1-PB.raw;0054_WU_FARMM_CMH_9030-1-PB.raw;0054_WUG_FARMM_FFA-9030-1-PB.raw"}
},
{
"Subject ID":"9030",
"Sample ID":"9030-1-PC",
"Factors":{"Study_Diet":"Western","Age":"46","Sex":"Male","Race":"White","Time":"Day 9"},
"Additional sample data":{"Type":"Plasma","BMI":"27.7","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0055_WUG_FARMM_HIL-9030-1-PC.raw;0055_WUG_FARMM_LIP-9030-1-PC.raw;0055_WU_FARMM_CMH_9030-1-PC.raw;0055_WUG_FARMM_FFA-9030-1-PC.raw"}
},
{
"Subject ID":"9030",
"Sample ID":"9030-1-PD",
"Factors":{"Study_Diet":"Western","Age":"46","Sex":"Male","Race":"White","Time":"Day 5"},
"Additional sample data":{"Type":"Plasma","BMI":"27.7","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0051_WUG_FARMM_HIL-9030-1-PD.raw;0051_WUG_FARMM_LIP-9030-1-PD.raw;0051_WU_FARMM_CMH_9030-1-PD.raw;0051_WUG_FARMM_FFA-9030-1-PD.raw"}
},
{
"Subject ID":"9030",
"Sample ID":"9030-1-PE",
"Factors":{"Study_Diet":"Western","Age":"46","Sex":"Male","Race":"White","Time":"Baseline"},
"Additional sample data":{"Type":"Plasma","BMI":"27.7","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0052_WUG_FARMM_HIL-9030-1-PE.raw;0052_WUG_FARMM_LIP-9030-1-PE.raw;0052_WU_FARMM_CMH_9030-1-PE.raw;0052_WUG_FARMM_FFA-9030-1-PE.raw"}
},
{
"Subject ID":"9031",
"Sample ID":"9031-3-PA",
"Factors":{"Study_Diet":"Vegan","Age":"32","Sex":"Female","Race":"White","Time":"Day 15"},
"Additional sample data":{"Type":"Plasma","BMI":"22.8","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0019_WUG_FARMM_HIL-9031-3-PA.raw;0019_WUG_FARMM_LIP-9031-3-PA.raw;0019_WU_FARMM_CMH_9031-3-PA.raw;0019_WUG_FARMM_FFA-9031-3-PA.raw"}
},
{
"Subject ID":"9031",
"Sample ID":"9031-3-PB",
"Factors":{"Study_Diet":"Vegan","Age":"32","Sex":"Female","Race":"White","Time":"Day 12"},
"Additional sample data":{"Type":"Plasma","BMI":"22.8","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0018_WUG_FARMM_HIL-9031-3-PB.raw;0018_WUG_FARMM_LIP-9031-3-PB.raw;0018_WU_FARMM_CMH_9031-3-PB.raw;0018_WUG_FARMM_FFA-9031-3-PB.raw"}
},
{
"Subject ID":"9031",
"Sample ID":"9031-3-PC",
"Factors":{"Study_Diet":"Vegan","Age":"32","Sex":"Female","Race":"White","Time":"Day 9"},
"Additional sample data":{"Type":"Plasma","BMI":"22.8","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0020_WUG_FARMM_HIL-9031-3-PC.raw;0020_WUG_FARMM_LIP-9031-3-PC.raw;0020_WU_FARMM_CMH_9031-3-PC.raw;0020_WUG_FARMM_FFA-9031-3-PC.raw"}
},
{
"Subject ID":"9031",
"Sample ID":"9031-3-PD",
"Factors":{"Study_Diet":"Vegan","Age":"32","Sex":"Female","Race":"White","Time":"Day 5"},
"Additional sample data":{"Type":"Plasma","BMI":"22.8","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0016_WUG_FARMM_HIL-9031-3-PD.raw;0016_WUG_FARMM_LIP-9031-3-PD.raw;0016_WU_FARMM_CMH_9031-3-PD.raw;0016_WUG_FARMM_FFA-9031-3-PD.raw"}
},
{
"Subject ID":"9031",
"Sample ID":"9031-3-PE",
"Factors":{"Study_Diet":"Vegan","Age":"32","Sex":"Female","Race":"White","Time":"Baseline"},
"Additional sample data":{"Type":"Plasma","BMI":"22.8","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0017_WUG_FARMM_HIL-9031-3-PE.raw;0017_WUG_FARMM_LIP-9031-3-PE.raw;0017_WU_FARMM_CMH_9031-3-PE.raw;0017_WUG_FARMM_FFA-9031-3-PE.raw"}
},
{
"Subject ID":"9032",
"Sample ID":"9032-2-PA",
"Factors":{"Study_Diet":"Modulen","Age":"53","Sex":"Male","Race":"White","Time":"Day 15"},
"Additional sample data":{"Type":"Plasma","BMI":"31","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0111_WUG_FARMM_HIL-9032-2-PA.raw;0111_WUG_FARMM_LIP-9032-2-PA.raw;0111_WU_FARMM_CMH_9032-2-PA.raw;0111_WUG_FARMM_FFA-9032-2-PA.raw"}
},
{
"Subject ID":"9032",
"Sample ID":"9032-2-PB",
"Factors":{"Study_Diet":"Modulen","Age":"53","Sex":"Male","Race":"White","Time":"Day 12"},
"Additional sample data":{"Type":"Plasma","BMI":"31","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0114_WUG_FARMM_HIL-9032-2-PB.raw;0114_WUG_FARMM_LIP-9032-2-PB.raw;0114_WU_FARMM_CMH_9032-2-PB.raw;0114_WUG_FARMM_FFA-9032-2-PB.raw"}
},
{
"Subject ID":"9032",
"Sample ID":"9032-2-PC",
"Factors":{"Study_Diet":"Modulen","Age":"53","Sex":"Male","Race":"White","Time":"Day 9"},
"Additional sample data":{"Type":"Plasma","BMI":"31","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0112_WUG_FARMM_HIL-9032-2-PC.raw;0112_WUG_FARMM_LIP-9032-2-PC.raw;0112_WU_FARMM_CMH_9032-2-PC.raw;0112_WUG_FARMM_FFA-9032-2-PC.raw"}
},
{
"Subject ID":"9032",
"Sample ID":"9032-2-PD",
"Factors":{"Study_Diet":"Modulen","Age":"53","Sex":"Male","Race":"White","Time":"Day 5"},
"Additional sample data":{"Type":"Plasma","BMI":"31","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0113_WUG_FARMM_HIL-9032-2-PD.raw;0113_WUG_FARMM_LIP-9032-2-PD.raw;0113_WU_FARMM_CMH_9032-2-PD.raw;0113_WUG_FARMM_FFA-9032-2-PD.raw"}
},
{
"Subject ID":"9032",
"Sample ID":"9032-2-PE",
"Factors":{"Study_Diet":"Modulen","Age":"53","Sex":"Male","Race":"White","Time":"Baseline"},
"Additional sample data":{"Type":"Plasma","BMI":"31","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0115_WUG_FARMM_HIL-9032-2-PE.raw;0115_WUG_FARMM_LIP-9032-2-PE.raw;0115_WU_FARMM_CMH_9032-2-PE.raw;0115_WUG_FARMM_FFA-9032-2-PE.raw"}
},
{
"Subject ID":"9033",
"Sample ID":"9033-1-PA",
"Factors":{"Study_Diet":"Western","Age":"57","Sex":"Male","Race":"White","Time":"Day 15"},
"Additional sample data":{"Type":"Plasma","BMI":"27.1","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0033_WUG_FARMM_HIL-9033-1-PA.raw;0033_WUG_FARMM_LIP-9033-1-PA.raw;0033_WU_FARMM_CMH_9033-1-PA.raw;0033_WUG_FARMM_FFA-9033-1-PA.raw"}
},
{
"Subject ID":"9033",
"Sample ID":"9033-1-PB",
"Factors":{"Study_Diet":"Western","Age":"57","Sex":"Male","Race":"White","Time":"Day 12"},
"Additional sample data":{"Type":"Plasma","BMI":"27.1","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0031_WUG_FARMM_HIL-9033-1-PB.raw;0031_WUG_FARMM_LIP-9033-1-PB.raw;0031_WU_FARMM_CMH_9033-1-PB.raw;0031_WUG_FARMM_FFA-9033-1-PB.raw"}
},
{
"Subject ID":"9033",
"Sample ID":"9033-1-PC",
"Factors":{"Study_Diet":"Western","Age":"57","Sex":"Male","Race":"White","Time":"Day 9"},
"Additional sample data":{"Type":"Plasma","BMI":"27.1","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0034_WUG_FARMM_HIL-9033-1-PC.raw;0034_WUG_FARMM_LIP-9033-1-PC.raw;0034_WU_FARMM_CMH_9033-1-PC.raw;0034_WUG_FARMM_FFA-9033-1-PC.raw"}
},
{
"Subject ID":"9033",
"Sample ID":"9033-1-PD",
"Factors":{"Study_Diet":"Western","Age":"57","Sex":"Male","Race":"White","Time":"Day 5"},
"Additional sample data":{"Type":"Plasma","BMI":"27.1","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0035_WUG_FARMM_HIL-9033-1-PD.raw;0035_WUG_FARMM_LIP-9033-1-PD.raw;0035_WU_FARMM_CMH_9033-1-PD.raw;0035_WUG_FARMM_FFA-9033-1-PD.raw"}
},
{
"Subject ID":"9033",
"Sample ID":"9033-1-PE",
"Factors":{"Study_Diet":"Western","Age":"57","Sex":"Male","Race":"White","Time":"Baseline"},
"Additional sample data":{"Type":"Plasma","BMI":"27.1","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0032_WUG_FARMM_HIL-9033-1-PE.raw;0032_WUG_FARMM_LIP-9033-1-PE.raw;0032_WU_FARMM_CMH_9033-1-PE.raw;0032_WUG_FARMM_FFA-9033-1-PE.raw"}
},
{
"Subject ID":"9034",
"Sample ID":"9034-2-PA",
"Factors":{"Study_Diet":"Modulen","Age":"43","Sex":"Female","Race":"White","Time":"Day 15"},
"Additional sample data":{"Type":"Plasma","BMI":"25.3","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0024_WUG_FARMM_HIL-9034-2-PA.raw;0024_WUG_FARMM_LIP-9034-2-PA.raw;0024_WU_FARMM_CMH_9034-2-PA.raw;0024_WUG_FARMM_FFA-9034-2-PA.raw"}
},
{
"Subject ID":"9034",
"Sample ID":"9034-2-PB",
"Factors":{"Study_Diet":"Modulen","Age":"43","Sex":"Female","Race":"White","Time":"Day 12"},
"Additional sample data":{"Type":"Plasma","BMI":"25.3","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0023_WUG_FARMM_HIL-9034-2-PB.raw;0023_WUG_FARMM_LIP-9034-2-PB.raw;0023_WU_FARMM_CMH_9034-2-PB.raw;0023_WUG_FARMM_FFA-9034-2-PB.raw"}
},
{
"Subject ID":"9034",
"Sample ID":"9034-2-PC",
"Factors":{"Study_Diet":"Modulen","Age":"43","Sex":"Female","Race":"White","Time":"Day 9"},
"Additional sample data":{"Type":"Plasma","BMI":"25.3","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0025_WUG_FARMM_HIL-9034-2-PC.raw;0025_WUG_FARMM_LIP-9034-2-PC.raw;0025_WU_FARMM_CMH_9034-2-PC.raw;0025_WUG_FARMM_FFA-9034-2-PC.raw"}
},
{
"Subject ID":"9034",
"Sample ID":"9034-2-PD",
"Factors":{"Study_Diet":"Modulen","Age":"43","Sex":"Female","Race":"White","Time":"Day 5"},
"Additional sample data":{"Type":"Plasma","BMI":"25.3","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0021_WUG_FARMM_HIL-9034-2-PD.raw;0021_WUG_FARMM_LIP-9034-2-PD.raw;0021_WU_FARMM_CMH_9034-2-PD.raw;0021_WUG_FARMM_FFA-9034-2-PD.raw"}
},
{
"Subject ID":"9034",
"Sample ID":"9034-2-PE",
"Factors":{"Study_Diet":"Modulen","Age":"43","Sex":"Female","Race":"White","Time":"Baseline"},
"Additional sample data":{"Type":"Plasma","BMI":"25.3","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0022_WUG_FARMM_HIL-9034-2-PE.raw;0022_WUG_FARMM_LIP-9034-2-PE.raw;0022_WU_FARMM_CMH_9034-2-PE.raw;0022_WUG_FARMM_FFA-9034-2-PE.raw"}
},
{
"Subject ID":"9035",
"Sample ID":"9035-3-PA",
"Factors":{"Study_Diet":"Vegan","Age":"25","Sex":"Male","Race":"White","Time":"Day 15"},
"Additional sample data":{"Type":"Plasma","BMI":"19.7","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0140_WUG_FARMM_HIL-9035-3-PA.raw;0140_WUG_FARMM_LIP-9035-3-PA.raw;0140_WU_FARMM_CMH_9035-3-PA.raw;0140_WUG_FARMM_FFA-9035-3-PA.raw"}
},
{
"Subject ID":"9035",
"Sample ID":"9035-3-PB",
"Factors":{"Study_Diet":"Vegan","Age":"25","Sex":"Male","Race":"White","Time":"Day 12"},
"Additional sample data":{"Type":"Plasma","BMI":"19.7","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0138_WUG_FARMM_HIL-9035-3-PB.raw;0138_WUG_FARMM_LIP-9035-3-PB.raw;0138_WU_FARMM_CMH_9035-3-PB.raw;0138_WUG_FARMM_FFA-9035-3-PB.raw"}
},
{
"Subject ID":"9035",
"Sample ID":"9035-3-PC",
"Factors":{"Study_Diet":"Vegan","Age":"25","Sex":"Male","Race":"White","Time":"Day 9"},
"Additional sample data":{"Type":"Plasma","BMI":"19.7","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0137_WUG_FARMM_HIL-9035-3-PC.raw;0137_WUG_FARMM_LIP-9035-3-PC.raw;0137_WU_FARMM_CMH_9035-3-PC.raw;0137_WUG_FARMM_FFA-9035-3-PC.raw"}
},
{
"Subject ID":"9035",
"Sample ID":"9035-3-PD",
"Factors":{"Study_Diet":"Vegan","Age":"25","Sex":"Male","Race":"White","Time":"Day 5"},
"Additional sample data":{"Type":"Plasma","BMI":"19.7","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0136_WUG_FARMM_HIL-9035-3-PD.raw;0136_WUG_FARMM_LIP-9035-3-PD.raw;0136_WU_FARMM_CMH_9035-3-PD.raw;0136_WUG_FARMM_FFA-9035-3-PD.raw"}
},
{
"Subject ID":"9035",
"Sample ID":"9035-3-PE",
"Factors":{"Study_Diet":"Vegan","Age":"25","Sex":"Male","Race":"White","Time":"Baseline"},
"Additional sample data":{"Type":"Plasma","BMI":"19.7","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0139_WUG_FARMM_HIL-9035-3-PE.raw;0139_WUG_FARMM_LIP-9035-3-PE.raw;0139_WU_FARMM_CMH_9035-3-PE.raw;0139_WUG_FARMM_FFA-9035-3-PE.raw"}
},
{
"Subject ID":"9036",
"Sample ID":"9036-1-PA",
"Factors":{"Study_Diet":"Western","Age":"60","Sex":"Male","Race":"American Indian/Alaskan Native","Time":"White"},
"Additional sample data":{"Type":"Plasma","BMI":"23.9","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"Day 15"}
},
{
"Subject ID":"9036",
"Sample ID":"9036-1-PB",
"Factors":{"Study_Diet":"Western","Age":"60","Sex":"Male","Race":"American Indian/Alaskan Native","Time":"White"},
"Additional sample data":{"Type":"Plasma","BMI":"23.9","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"Day 12"}
},
{
"Subject ID":"9036",
"Sample ID":"9036-1-PC",
"Factors":{"Study_Diet":"Western","Age":"60","Sex":"Male","Race":"American Indian/Alaskan Native","Time":"White"},
"Additional sample data":{"Type":"Plasma","BMI":"23.9","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"Day 9"}
},
{
"Subject ID":"9036",
"Sample ID":"9036-1-PD",
"Factors":{"Study_Diet":"Western","Age":"60","Sex":"Male","Race":"American Indian/Alaskan Native","Time":"White"},
"Additional sample data":{"Type":"Plasma","BMI":"23.9","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"Day 5"}
},
{
"Subject ID":"9036",
"Sample ID":"9036-1-PE",
"Factors":{"Study_Diet":"Western","Age":"60","Sex":"Male","Race":"American Indian/Alaskan Native","Time":"White"},
"Additional sample data":{"Type":"Plasma","BMI":"23.9","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"Baseline"}
},
{
"Subject ID":"9037",
"Sample ID":"9037-1-PA",
"Factors":{"Study_Diet":"Western","Age":"29","Sex":"Male","Race":"Black/African American","Time":"White"},
"Additional sample data":{"Type":"Plasma","BMI":"23","Ethnicity":"Hispanic or Latino","RAW_FILE_NAME":"Day 15"}
},
{
"Subject ID":"9037",
"Sample ID":"9037-1-PB",
"Factors":{"Study_Diet":"Western","Age":"29","Sex":"Male","Race":"Black/African American","Time":"White"},
"Additional sample data":{"Type":"Plasma","BMI":"23","Ethnicity":"Hispanic or Latino","RAW_FILE_NAME":"Day 12"}
},
{
"Subject ID":"9037",
"Sample ID":"9037-1-PC",
"Factors":{"Study_Diet":"Western","Age":"29","Sex":"Male","Race":"Black/African American","Time":"White"},
"Additional sample data":{"Type":"Plasma","BMI":"23","Ethnicity":"Hispanic or Latino","RAW_FILE_NAME":"Day 9"}
},
{
"Subject ID":"9037",
"Sample ID":"9037-1-PD",
"Factors":{"Study_Diet":"Western","Age":"29","Sex":"Male","Race":"Black/African American","Time":"White"},
"Additional sample data":{"Type":"Plasma","BMI":"23","Ethnicity":"Hispanic or Latino","RAW_FILE_NAME":"Day 5"}
},
{
"Subject ID":"9037",
"Sample ID":"9037-1-PE",
"Factors":{"Study_Diet":"Western","Age":"29","Sex":"Male","Race":"Black/African American","Time":"White"},
"Additional sample data":{"Type":"Plasma","BMI":"23","Ethnicity":"Hispanic or Latino","RAW_FILE_NAME":"Baseline"}
},
{
"Subject ID":"9038",
"Sample ID":"9038-2-PA",
"Factors":{"Study_Diet":"Modulen","Age":"59","Sex":"Female","Race":"White","Time":"Day 15"},
"Additional sample data":{"Type":"Plasma","BMI":"34.3","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0086_WUG_FARMM_HIL-9038-2-PA.raw;0086_WUG_FARMM_LIP-9038-2-PA.raw;0086_WU_FARMM_CMH_9038-2-PA.raw;0086_WUG_FARMM_FFA-9038-2-PA.raw"}
},
{
"Subject ID":"9038",
"Sample ID":"9038-2-PB",
"Factors":{"Study_Diet":"Modulen","Age":"59","Sex":"Female","Race":"White","Time":"Day 12"},
"Additional sample data":{"Type":"Plasma","BMI":"34.3","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0090_WUG_FARMM_HIL-9038-2-PB.raw;0090_WUG_FARMM_LIP-9038-2-PB.raw;0090_WU_FARMM_CMH_9038-2-PB.raw;0090_WUG_FARMM_FFA-9038-2-PB.raw"}
},
{
"Subject ID":"9038",
"Sample ID":"9038-2-PC",
"Factors":{"Study_Diet":"Modulen","Age":"59","Sex":"Female","Race":"White","Time":"Day 9"},
"Additional sample data":{"Type":"Plasma","BMI":"34.3","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0088_WUG_FARMM_HIL-9038-2-PC.raw;0088_WUG_FARMM_LIP-9038-2-PC.raw;0088_WU_FARMM_CMH_9038-2-PC.raw;0088_WUG_FARMM_FFA-9038-2-PC.raw"}
},
{
"Subject ID":"9038",
"Sample ID":"9038-2-PD",
"Factors":{"Study_Diet":"Modulen","Age":"59","Sex":"Female","Race":"White","Time":"Day 5"},
"Additional sample data":{"Type":"Plasma","BMI":"34.3","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0089_WUG_FARMM_HIL-9038-2-PD.raw;0089_WUG_FARMM_LIP-9038-2-PD.raw;0089_WU_FARMM_CMH_9038-2-PD.raw;0089_WUG_FARMM_FFA-9038-2-PD.raw"}
},
{
"Subject ID":"9038",
"Sample ID":"9038-2-PE",
"Factors":{"Study_Diet":"Modulen","Age":"59","Sex":"Female","Race":"White","Time":"Baseline"},
"Additional sample data":{"Type":"Plasma","BMI":"34.3","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0087_WUG_FARMM_HIL-9038-2-PE.raw;0087_WUG_FARMM_LIP-9038-2-PE.raw;0087_WU_FARMM_CMH_9038-2-PE.raw;0087_WUG_FARMM_FFA-9038-2-PE.raw"}
},
{
"Subject ID":"9040",
"Sample ID":"9040-1-PA",
"Factors":{"Study_Diet":"Western","Age":"22","Sex":"Male","Race":"White","Time":"Day 15"},
"Additional sample data":{"Type":"Plasma","BMI":"23.7","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0120_WUG_FARMM_HIL-9040-1-PA.raw;0120_WUG_FARMM_LIP-9040-1-PA.raw;0120_WU_FARMM_CMH_9040-1-PA.raw;0120_WUG_FARMM_FFA-9040-1-PA.raw"}
},
{
"Subject ID":"9040",
"Sample ID":"9040-1-PB",
"Factors":{"Study_Diet":"Western","Age":"22","Sex":"Male","Race":"White","Time":"Day 12"},
"Additional sample data":{"Type":"Plasma","BMI":"23.7","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0116_WUG_FARMM_HIL-9040-1-PB.raw;0116_WUG_FARMM_LIP-9040-1-PB.raw;0116_WU_FARMM_CMH_9040-1-PB.raw;0116_WUG_FARMM_FFA-9040-1-PB.raw"}
},
{
"Subject ID":"9040",
"Sample ID":"9040-1-PC",
"Factors":{"Study_Diet":"Western","Age":"22","Sex":"Male","Race":"White","Time":"Day 9"},
"Additional sample data":{"Type":"Plasma","BMI":"23.7","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0119_WUG_FARMM_HIL-9040-1-PC.raw;0119_WUG_FARMM_LIP-9040-1-PC.raw;0119_WU_FARMM_CMH_9040-1-PC.raw;0119_WUG_FARMM_FFA-9040-1-PC.raw"}
},
{
"Subject ID":"9040",
"Sample ID":"9040-1-PD",
"Factors":{"Study_Diet":"Western","Age":"22","Sex":"Male","Race":"White","Time":"Day 5"},
"Additional sample data":{"Type":"Plasma","BMI":"23.7","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0117_WUG_FARMM_HIL-9040-1-PD.raw;0117_WUG_FARMM_LIP-9040-1-PD.raw;0117_WU_FARMM_CMH_9040-1-PD.raw;0117_WUG_FARMM_FFA-9040-1-PD.raw"}
},
{
"Subject ID":"9040",
"Sample ID":"9040-1-PE",
"Factors":{"Study_Diet":"Western","Age":"22","Sex":"Male","Race":"White","Time":"Baseline"},
"Additional sample data":{"Type":"Plasma","BMI":"23.7","Ethnicity":"Not Hispanic or Latino","RAW_FILE_NAME":"0118_WUG_FARMM_HIL-9040-1-PE.raw;0150f_0118ri_WUG_FARMM_LIP-9040-1-PE.raw;0118_WU_FARMM_CMH_9040-1-PE.raw;0118_WUG_FARMM_FFA-9040-1-PE.raw"}
},
{
"Subject ID":"QC-pooled_plasma",
"Sample ID":"QPP01",
"Factors":{"Study_Diet":"NA","Age":"NA","Sex":"NA","Race":"NA","Time":"NA"},
"Additional sample data":{"Type":"Plasma","BMI":"NA","Ethnicity":"NA","RAW_FILE_NAME":"NA;NA;0000d_WU_FARMM_CMH_QPP-01.raw;NA"}
},
{
"Subject ID":"QC-pooled_plasma",
"Sample ID":"QPP02",
"Factors":{"Study_Diet":"NA","Age":"NA","Sex":"NA","Race":"NA","Time":"NA"},
"Additional sample data":{"Type":"Plasma","BMI":"NA","Ethnicity":"NA","RAW_FILE_NAME":"0020a_WUG_FARMM_HIL-QPP02.raw;0020a_WUG_FARMM_LIP-QCPP02.raw;0020a_WU_FARMM_CMH_QPP-02.raw;0020a_WUG_FARMM_FFA-QCPP02.raw"}
},
{
"Subject ID":"QC-pooled_plasma",
"Sample ID":"QPP03",
"Factors":{"Study_Diet":"NA","Age":"NA","Sex":"NA","Race":"NA","Time":"NA"},
"Additional sample data":{"Type":"Plasma","BMI":"NA","Ethnicity":"NA","RAW_FILE_NAME":"0040a_WUG_FARMM_HIL-QPP03.raw;NA;0040a_WU_FARMM_CMH_QPP-03.raw;0040a_WUG_FARMM_FFA-QCPP03.raw"}
},
{
"Subject ID":"QC-pooled_plasma",
"Sample ID":"QPP04",
"Factors":{"Study_Diet":"NA","Age":"NA","Sex":"NA","Race":"NA","Time":"NA"},
"Additional sample data":{"Type":"Plasma","BMI":"NA","Ethnicity":"NA","RAW_FILE_NAME":"0060a_WUG_FARMM_HIL-QPP04.raw;0060a_WUG_FARMM_LIP-QCPP04.raw;0060a_WU_FARMM_CMH_QPP-04.raw;0060a_WUG_FARMM_FFA-QCPP04.raw"}
},
{
"Subject ID":"QC-pooled_plasma",
"Sample ID":"QPP05",
"Factors":{"Study_Diet":"NA","Age":"NA","Sex":"NA","Race":"NA","Time":"NA"},
"Additional sample data":{"Type":"Plasma","BMI":"NA","Ethnicity":"NA","RAW_FILE_NAME":"0080a_WUG_FARMM_HIL-QPP05.raw;0080a_WUG_FARMM_LIP-QCPP05.raw;0080a_WU_FARMM_CMH_QPP-05.raw;0080a_WUG_FARMM_FFA-QCPP05.raw"}
},
{
"Subject ID":"QC-pooled_plasma",
"Sample ID":"QPP06",
"Factors":{"Study_Diet":"NA","Age":"NA","Sex":"NA","Race":"NA","Time":"NA"},
"Additional sample data":{"Type":"Plasma","BMI":"NA","Ethnicity":"NA","RAW_FILE_NAME":"0100a_WUG_FARMM_HIL-QPP06.raw;0100a_WUG_FARMM_LIP-QCPP06.raw;0080d_WU_FARMM_CMH_QPP-06.raw;0100a_WUG_FARMM_FFA-QCPP06.raw"}
},
{
"Subject ID":"QC-pooled_plasma",
"Sample ID":"QPP07",
"Factors":{"Study_Diet":"NA","Age":"NA","Sex":"NA","Race":"NA","Time":"NA"},
"Additional sample data":{"Type":"Plasma","BMI":"NA","Ethnicity":"NA","RAW_FILE_NAME":"0120a_WUG_FARMM_HIL-QPP07.raw;NA;0100a_WU_FARMM_CMH_QPP-07.raw;0120a_WUG_FARMM_FFA-QCPP07.raw"}
},
{
"Subject ID":"QC-pooled_plasma",
"Sample ID":"QPP08",
"Factors":{"Study_Diet":"NA","Age":"NA","Sex":"NA","Race":"NA","Time":"NA"},
"Additional sample data":{"Type":"Plasma","BMI":"NA","Ethnicity":"NA","RAW_FILE_NAME":"0140a_WUG_FARMM_HIL-QPP08.raw;0150a_WUG_FARMM_LIP-QCPP08.raw;0120a_WU_FARMM_CMH_QPP-08.raw;0150a_WUG_FARMM_FFA-QCPP08.raw"}
},
{
"Subject ID":"QC-pooled_plasma",
"Sample ID":"QPP09",
"Factors":{"Study_Diet":"NA","Age":"NA","Sex":"NA","Race":"NA","Time":"NA"},
"Additional sample data":{"Type":"Plasma","BMI":"NA","Ethnicity":"NA","RAW_FILE_NAME":"0150a_WUG_FARMM_HIL-QPP09.raw;NA;0140a_WU_FARMM_CMH_QPP-09.raw;NA"}
},
{
"Subject ID":"QC-pooled_plasma",
"Sample ID":"QPP10",
"Factors":{"Study_Diet":"NA","Age":"NA","Sex":"NA","Race":"NA","Time":"NA"},
"Additional sample data":{"Type":"Plasma","BMI":"NA","Ethnicity":"NA","RAW_FILE_NAME":"NA;NA;0150a_WU_FARMM_CMH_QPP-10.raw;NA"}
}
],
"COLLECTION":{"COLLECTION_SUMMARY":"The first stool sample of each day of the inpatient groups was collected, aliquoted and frozen immediately at -80oC. Blood was collected on days 1, 5, 9, 12 and 15 from which plasma aliquots were immediately isolated and frozen at -80oC. The outpatient participants following the vegan diet also had blood collected on days 1, 5, 9, 12, and 15 from which plasma aliquots were immediately isolated and frozen at -80oC. Among these participants, the first stool of the day was collected at home daily and kept on ice packs until it was brought to the research unit where it could be aliquoted and frozen. Samples from vegans were received for aliquoting within 24 hours and on average within 4 hours (Wu et al., 2010). Day 0 stool was not collected from vegans since their diet did not change. The aliquoted amounts for all samples ranged from 500 mg to 1 g. The aliquots were taken from different areas of the sample. Remaining sample was then collected into one residual 50 ml conical tube with a tongue depressor. Any remaining stool was discarded. The University of Pennsylvania Institutional Review Board (IRB) approved the research protocol.","SAMPLE_TYPE":"Blood (plasma)","STORAGE_CONDITIONS":"-80℃"},

"TREATMENT":{"TREATMENT_SUMMARY":"The 10 vegan participants continued to follow their usual diet as outpatients. All participants completed the Diet History Questionnaire II (DHQ II), a food frequency questionnaire developed by the Risk Factor Monitoring and Methods Branch of the National Cancer Institute. The vegan participants also completed three 24 hour diet recalls with a dietitian in the week prior to starting antibiotics. 20 omnivores were randomly assigned to receive an omnivore diet or EEN (Modulen® IBD) while residing in an inpatient research unit. The macronutrient composition of Modulen® is protein 36g, fat 47g, and carbohydrate 110g per 1000 Kcal. The two omnivore diets were engineered to have a similar composition to EEN. All the subjects consumed the menu A on day 11 and menu B on days 4 and 14. Diets for omnivores were constructed to provide the expected total calories required per day for the participant to maintain their current weight and were adjusted if there was weight gain or loss of more than 2.5 pounds. On days 6, 7, and 8, inpatients participants received vancomycin 500mg orally every 6 hours and neomycin 1000mg orally every 6 hours. On day 7, participants consumed 4L of polyethylene glycol (PEG) based bowel purgative (GoLytely®). Participants in the omnivore and EEN arms left the inpatient research unit only under the direct supervision of a research staff member. The vegan outpatients reported to the hospital twice on days 6,7 and 8 to receive antibiotics and to consume PEG on day 7."},

"SAMPLEPREP":{"SAMPLEPREP_SUMMARY":"Plasma samples were thawed on ice and aliquoted for metabolite profiling analyses. Plasma samples were thawed and aliquoted for each LC-MS method. LC-MS samples were prepared for four profiling methods as follows: HILIC-pos: Metabolites were extracted by adding 90 μL of 74.9:24.9:0.2 v/v/v acetonitrile/methanol/formic acid containing stable isotope-labeled internal standards (valine-d8, Isotec; and phenylalanine-d8, Cambridge Isotope Laboratories; Andover, MA) to a 10 μL aliquot of stool homogenate or plasma. Samples were vortexed and then centrifuged (10 min, 9,000 x g, 4°C) to pellet protein precipitates. Supernatants were transferred to glass autosampler vials containing inserts for LC-MS analysis. C8-pos: Lipids were extracted by adding 190 μL of isopropanol containing 1-dodecanoyl-2-tridecanoyl-sn-glycero-3-phosphocholine as an internal standard (Avanti Polar Lipids; Alabaster, AL) to a 10 μL aliquot of stool homogenate or plasma. Samples were vortexed and then centrifuged (10 min, 9,000 x g, ambient temperature) to pellet protein precipitates. Supernatants were transferred to glass autosampler vials containing inserts for LC-MS analysis. HILIC-neg: Metabolites were extracted by adding 120 μL of 80% methanol containing inosine-15N4, thymine-d4 and glycocholate-d4 internal standards (Cambridge Isotope Laboratories; Andover, MA) to a 30 μL aliquot of stool homogenate or plasma. Samples were vortexed and then centrifuged (10 min, 9,000 x g, 4°C) to pellet protein precipitates. Supernatants were transferred to glass autosampler vials containing inserts for LC-MS analysis. C18-neg: Metabolites were extracted by adding 90 μL of methanol containing PGE2-d4 as an internal standard (Cayman Chemical Co.; Ann Arbor, MI) to a 30 μL aliquot of stool homogenate or plasma. Samples were vortexed and then centrifuged (10 min, 9,000 x g, 4°C) to pellet protein precipitates. Supernatants were transferred to glass autosampler vials containing inserts for LC-MS analysis."},

"CHROMATOGRAPHY":{"CHROMATOGRAPHY_SUMMARY":"C18-neg: high resolution and accurate mass profiling of metabolites of intermediate polarity using reversed phase C18 chromatography and negative ion mode full scan MS","CHROMATOGRAPHY_TYPE":"Reversed phase","INSTRUMENT_NAME":"Shimadzu Nexera X2","COLUMN_NAME":"Waters Acquity T3 (150 x 2.1 mm, 1.7 um)","FLOW_GRADIENT":"linear","FLOW_RATE":"450 uL/min","COLUMN_TEMPERATURE":"45 ℃","SOLVENT_A":"0.01% Formic acid in water","SOLVENT_B":"0.01% Acetic acid in Acetonitrile","INJECTION_TEMPERATURE":"4"},

"ANALYSIS":{"ANALYSIS_TYPE":"MS"},

"MS":{"INSTRUMENT_NAME":"Thermo Q Exactive Orbitrap","INSTRUMENT_TYPE":"Orbitrap","MS_TYPE":"ESI","ION_MODE":"NEGATIVE","MS_COMMENTS":"MS analyses were carried out using electrospray ionization in the negative ion mode using full scan analysis over m/z 70-850 at 70,000 resolution and 3 Hz data acquisition rate. Additional MS settings were: ion spray voltage, -3.5 kV; capillary temperature, 320°C; probe heater temperature, 300°C; sheath gas, 45; auxiliary gas, 10; and S-lens RF level 60All raw data were processed using Progenesis QI software (NonLinear Dynamics) for feature alignment, nontargeted signal detection, and signal integration. Targeted processing of a subset of known metabolites was conducted using TraceFinder software (Thermo Fisher Scientific; Waltham, MA). Compound identities were confirmed using reference standards."},

"MS_METABOLITE_DATA":{
"Units":"unitless peak areas",

"Data":[{"Metabolite":"PEGE2-d4 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(min)":"0.89"},{"Metabolite":"Oxypurinol","m/z":"151.0261","RT (min)":"0.71"},{"Metabolite":"Palmitoyl-EA","m/z":"344.2804","RT (min)":"13.39"},{"Metabolite":"Phenyllactic acid","m/z":"165.0544","RT (min)":"2.19"},{"Metabolite":"p-Hydroxyphenylacetic acid","m/z":"151.0401","RT (min)":"1.30"},{"Metabolite":"Pregnenolone sulfate","m/z":"395.1891","RT (min)":"8.41"},{"Metabolite":"Ribothymidine","m/z":"257.0779","RT (min)":"0.86"}]
}

}