{
"METABOLOMICS WORKBENCH":{"STUDY_ID":"ST001750","ANALYSIS_ID":"AN002853","VERSION":"1","CREATED_ON":"April 27, 2021, 8:03 am"},

"PROJECT":{"PROJECT_TITLE":"Gut microbiome influence on metabolic 1 disease in HIV and high-risk populations","PROJECT_SUMMARY":"Poor metabolic health, characterized by insulin resistance and dyslipidemia, is higher in people living with HIV (PLWH) and has been linked with inflammation, anti-retroviral therapy (ART) drugs, and ART-associated lipodystrophy (LD). Metabolic disease is associated with gut microbiome composition outside the context of HIV but has not been deeply explored in HIV infection nor in high-risk men who have sex with men (HR-MSM), who have a highly altered gut microbiome composition. Furthermore, the contribution of increased bacterial translocation and associated systemic inflammation that has been described in HIV-positive and HR-MSM individuals has not been explored. We used a multi-omic approach to explore relationships between gut microbes, immune phenotypes, diet, and metabolic health across ART-treated PLWH with and without .D  untreated PLWH; and HR-MSM. For PLWH on ART, we further explored associations with the plasma metabolome.","INSTITUTE":"University of Colorado Anschutz Medical Campus","LAST_NAME":"Reisdorph","FIRST_NAME":"Nichole","ADDRESS":"12850 East Montview Blvd, Aurora, CO, 80045, USA","EMAIL":"nichole.reisdorph@cuanschutz.edu","PHONE":"303-724-9234"},

"STUDY":{"STUDY_TITLE":"Gut microbiome influence on metabolic 1 disease in HIV and high-risk populations","STUDY_SUMMARY":"Poor metabolic health, characterized by insulin resistance and dyslipidemia, is higher in people living with HIV (PLWH) and has been linked with inflammation, anti-retroviral therapy (ART) drugs, and ART-associated lipodystrophy (LD). Metabolic disease is associated with gut microbiome composition outside the context of HIV but has not been deeply explored in HIV infection nor in high-risk men who have sex with men (HR-MSM), who have a highly altered gut microbiome composition. Furthermore, the contribution of increased bacterial translocation and associated systemic inflammation that has been described in HIV-positive and HR-MSM individuals has not been explored. We used a multi-omic approach to explore relationships between gut microbes, immune phenotypes, diet, and metabolic health across ART-treated PLWH with and without .D  untreated PLWH; and HR-MSM. For PLWH on ART, we further explored associations with the plasma metabolome.","INSTITUTE":"University of Colorado Anschutz Medical Campus","LAST_NAME":"Reisdorph","FIRST_NAME":"Nichole","ADDRESS":"12850 East Montview Blvd, Aurora, CO, 80045, USA","EMAIL":"nichole.reisdorph@cuanschutz.edu","PHONE":"303-724-9234"},

"SUBJECT":{"SUBJECT_TYPE":"Mammal","SUBJECT_SPECIES":"Homo sapiens","TAXONOMY_ID":"9606"},
"SUBJECT_SAMPLE_FACTORS":[
{
"Subject ID":"GLD009",
"Sample ID":"9",
"Factors":{"Sample_Type":"Human","Lipodystrophy":"NO","HIV_status":"Positive","Antiviral_Treatment":"Yes"},
"Additional sample data":{"RAW_FILE_NAME":"9","Age":"46","Gender":"Male","Race":"Black/African American","Hispanic":"No","Height":"176","Weight":"82.2","BMI":"26.5","Adiponectin":"3.8","Glucose":"71","HDL":"29","Insulin":"9","LDL":"83","Leptin":"9.8","Triglycerides":"82","Fasting":"Yes","CD4_CD38_single_positive_cells":"66","CD4_count":"819","CD4_HLADR_single_positive_cells":"2","CD4_percent":"27","CD4_HLADR_CD38_percent":"6","CD8_CD38_single_positive_cells":"13","CD8_count":"1335","CD8_HLADR_single_positive_cells":"20","CD8_percent":"44","CD8_HLADR_CD38_percent":"8","Lymphocyte_count":"3034","Lymphocyte_percent":"39.4"}
},
{
"Subject ID":"GLD019",
"Sample ID":"19",
"Factors":{"Sample_Type":"Human","Lipodystrophy":"NO","HIV_status":"Positive","Antiviral_Treatment":"Yes"},
"Additional sample data":{"RAW_FILE_NAME":"19","Age":"47","Gender":"Male","Race":"Black/African American","Hispanic":"No","Height":"186","Weight":"80","BMI":"23.1","Adiponectin":"28.1","Glucose":"80","HDL":"55","Insulin":"3","LDL":"110","Leptin":"2.9","Triglycerides":"78","Fasting":"Yes","CD4_CD38_single_positive_cells":"63","CD4_count":"177","CD4_HLADR_single_positive_cells":"3","CD4_percent":"19","CD4_HLADR_CD38_percent":"5","CD8_CD38_single_positive_cells":"26","CD8_count":"503","CD8_HLADR_single_positive_cells":"9","CD8_percent":"54","CD8_HLADR_CD38_percent":"10","Lymphocyte_count":"931","Lymphocyte_percent":"17.9"}
},
{
"Subject ID":"GLD020",
"Sample ID":"20",
"Factors":{"Sample_Type":"Human","Lipodystrophy":"YES","HIV_status":"Positive","Antiviral_Treatment":"Yes"},
"Additional sample data":{"RAW_FILE_NAME":"20","Age":"54","Gender":"Male","Race":"White","Hispanic":"No","Height":"172","Weight":"74.9","BMI":"25.3","Adiponectin":"2.7","Glucose":"93","HDL":"41","Insulin":"3","LDL":"126","Leptin":"2.2","Triglycerides":"66","Fasting":"Yes","CD4_CD38_single_positive_cells":"76","CD4_count":"1200","CD4_HLADR_single_positive_cells":"1","CD4_percent":"35","CD4_HLADR_CD38_percent":"1","CD8_CD38_single_positive_cells":"11","CD8_count":"1166","CD8_HLADR_single_positive_cells":"2","CD8_percent":"34","CD8_HLADR_CD38_percent":"2","Lymphocyte_count":"3429","Lymphocyte_percent":"43.4"}
},
{
"Subject ID":"GLD021",
"Sample ID":"21",
"Factors":{"Sample_Type":"Human","Lipodystrophy":"NO","HIV_status":"Positive","Antiviral_Treatment":"Yes"},
"Additional sample data":{"RAW_FILE_NAME":"21","Age":"58","Gender":"Male","Race":"White","Hispanic":"No","Height":"166","Weight":"67.5","BMI":"24.5","Adiponectin":"12.9","Glucose":"87","HDL":"40","Insulin":"3","LDL":"152","Leptin":"3","Triglycerides":"206","Fasting":"Yes","CD4_CD38_single_positive_cells":"71","CD4_count":"578","CD4_HLADR_single_positive_cells":"1","CD4_percent":"33","CD4_HLADR_CD38_percent":"3","CD8_CD38_single_positive_cells":"23","CD8_count":"910","CD8_HLADR_single_positive_cells":"11","CD8_percent":"52","CD8_HLADR_CD38_percent":"8","Lymphocyte_count":"1750","Lymphocyte_percent":"40.7"}
},
{
"Subject ID":"GLD022",
"Sample ID":"22",
"Factors":{"Sample_Type":"Human","Lipodystrophy":"YES","HIV_status":"Positive","Antiviral_Treatment":"Yes"},
"Additional sample data":{"RAW_FILE_NAME":"22","Age":"55","Gender":"Male","Race":"White","Hispanic":"Yes","Height":"173","Weight":"82","BMI":"27.4","Adiponectin":"7.7","Glucose":"77","HDL":"47","Insulin":"11","LDL":"80","Leptin":"9.6","Triglycerides":"153","Fasting":"Yes","CD4_CD38_single_positive_cells":"73","CD4_count":"545","CD4_HLADR_single_positive_cells":"2","CD4_percent":"19","CD4_HLADR_CD38_percent":"5","CD8_CD38_single_positive_cells":"36","CD8_count":"1399","CD8_HLADR_single_positive_cells":"14","CD8_percent":"49","CD8_HLADR_CD38_percent":"8","Lymphocyte_count":"2855","Lymphocyte_percent":"30.7"}
},
{
"Subject ID":"GLD023",
"Sample ID":"23",
"Factors":{"Sample_Type":"Human","Lipodystrophy":"NO","HIV_status":"Positive","Antiviral_Treatment":"Yes"},
"Additional sample data":{"RAW_FILE_NAME":"23","Age":"49","Gender":"Male","Race":"White","Hispanic":"No","Height":"177","Weight":"71.2","BMI":"22.7","Adiponectin":"17.8","Glucose":"87","HDL":"60","Insulin":"9","LDL":"99","Leptin":"3.7","Triglycerides":"89","Fasting":"Yes","CD4_CD38_single_positive_cells":"74","CD4_count":"510","CD4_HLADR_single_positive_cells":"1","CD4_percent":"35","CD4_HLADR_CD38_percent":"3","CD8_CD38_single_positive_cells":"30","CD8_count":"568","CD8_HLADR_single_positive_cells":"12","CD8_percent":"39","CD8_HLADR_CD38_percent":"12","Lymphocyte_count":"1456","Lymphocyte_percent":"36.4"}
},
{
"Subject ID":"GLD025",
"Sample ID":"25",
"Factors":{"Sample_Type":"Human","Lipodystrophy":"YES","HIV_status":"Positive","Antiviral_Treatment":"Yes"},
"Additional sample data":{"RAW_FILE_NAME":"25","Age":"67","Gender":"Male","Race":"White","Hispanic":"No","Height":"175","Weight":"90.9","BMI":"29.7","Adiponectin":"73","Glucose":"121","HDL":"51","Insulin":"9","LDL":"107","Leptin":"13.9","Triglycerides":"127","Fasting":"Yes","CD4_CD38_single_positive_cells":"45","CD4_count":"622","CD4_HLADR_single_positive_cells":"2","CD4_percent":"26","CD4_HLADR_CD38_percent":"5","CD8_CD38_single_positive_cells":"12","CD8_count":"1339","CD8_HLADR_single_positive_cells":"20","CD8_percent":"56","CD8_HLADR_CD38_percent":"7","Lymphocyte_count":"2391.9","Lymphocyte_percent":"46.9"}
},
{
"Subject ID":"GLD026",
"Sample ID":"26",
"Factors":{"Sample_Type":"Human","Lipodystrophy":"NO","HIV_status":"Positive","Antiviral_Treatment":"Yes"},
"Additional sample data":{"RAW_FILE_NAME":"26","Age":"53","Gender":"Male","Race":"Black/African American","Hispanic":"No","Height":"181","Weight":"88","BMI":"26.9","Adiponectin":"2.4","Glucose":"98","HDL":"43","Insulin":"13","LDL":"107","Leptin":"3.3","Triglycerides":"128","Fasting":"Yes","CD4_CD38_single_positive_cells":"31","CD4_count":"838","CD4_HLADR_single_positive_cells":"3","CD4_percent":"35","CD4_HLADR_CD38_percent":"2","CD8_CD38_single_positive_cells":"4","CD8_count":"838","CD8_HLADR_single_positive_cells":"8","CD8_percent":"35","CD8_HLADR_CD38_percent":"6","Lymphocyte_count":"2394","Lymphocyte_percent":"35.2"}
},
{
"Subject ID":"GLD027",
"Sample ID":"27",
"Factors":{"Sample_Type":"Human","Lipodystrophy":"NO","HIV_status":"Positive","Antiviral_Treatment":"Yes"},
"Additional sample data":{"RAW_FILE_NAME":"27","Age":"50","Gender":"Male","Race":"White","Hispanic":"No","Height":"179","Weight":"93","BMI":"29","Adiponectin":"3.7","Glucose":"90","HDL":"35","Insulin":"5","LDL":"85","Leptin":"5.4","Triglycerides":"584","Fasting":"Yes","CD4_CD38_single_positive_cells":"42","CD4_count":"648","CD4_HLADR_single_positive_cells":"2","CD4_percent":"39","CD4_HLADR_CD38_percent":"2","CD8_CD38_single_positive_cells":"11","CD8_count":"615","CD8_HLADR_single_positive_cells":"12","CD8_percent":"37","CD8_HLADR_CD38_percent":"5","Lymphocyte_count":"1661.6","Lymphocyte_percent":"26.8"}
},
{
"Subject ID":"GLD029",
"Sample ID":"29",
"Factors":{"Sample_Type":"Human","Lipodystrophy":"NO","HIV_status":"Positive","Antiviral_Treatment":"Yes"},
"Additional sample data":{"RAW_FILE_NAME":"29","Age":"44","Gender":"Male","Race":"White","Hispanic":"No","Height":"183","Weight":"96.9","BMI":"28.9","Adiponectin":"7","Glucose":"95","HDL":"43","Insulin":"6","LDL":"99","Leptin":"11.9","Triglycerides":"93","Fasting":"Yes","CD4_CD38_single_positive_cells":"1","CD4_count":"1114","CD4_HLADR_single_positive_cells":"1","CD4_percent":"52","CD4_HLADR_CD38_percent":"52","CD8_CD38_single_positive_cells":"12","CD8_count":"857","CD8_HLADR_single_positive_cells":"7","CD8_percent":"40","CD8_HLADR_CD38_percent":"9","Lymphocyte_count":"2142","Lymphocyte_percent":"34"}
},
{
"Subject ID":"GLD030",
"Sample ID":"30",
"Factors":{"Sample_Type":"Human","Lipodystrophy":"NO","HIV_status":"Positive","Antiviral_Treatment":"Yes"},
"Additional sample data":{"RAW_FILE_NAME":"30","Age":"37","Gender":"Male","Race":"White","Hispanic":"Yes","Height":"167","Weight":"71.9","BMI":"25.8","Adiponectin":"1.7","Glucose":"93","HDL":"43","Insulin":"5","LDL":"128","Leptin":"10.4","Triglycerides":"97","Fasting":"Yes","CD4_CD38_single_positive_cells":"57","CD4_count":"998","CD4_HLADR_single_positive_cells":"2","CD4_percent":"44","CD4_HLADR_CD38_percent":"2","CD8_CD38_single_positive_cells":"10","CD8_count":"885","CD8_HLADR_single_positive_cells":"8","CD8_percent":"39","CD8_HLADR_CD38_percent":"11","Lymphocyte_count":"2269","Lymphocyte_percent":"34.9"}
},
{
"Subject ID":"GLD036",
"Sample ID":"36",
"Factors":{"Sample_Type":"Human","Lipodystrophy":"NO","HIV_status":"Positive","Antiviral_Treatment":"Yes"},
"Additional sample data":{"RAW_FILE_NAME":"36","Age":"46","Gender":"Male","Race":"White","Hispanic":"No","Height":"182","Weight":"66.7","BMI":"20.1","Adiponectin":"8.8","Glucose":"87","HDL":"54","Insulin":"3","LDL":"79","Leptin":"0.7","Triglycerides":"61","Fasting":"Yes","CD4_CD38_single_positive_cells":"81","CD4_count":"334","CD4_HLADR_single_positive_cells":"2","CD4_percent":"22","CD4_HLADR_CD38_percent":"4","CD8_CD38_single_positive_cells":"52","CD8_count":"713","CD8_HLADR_single_positive_cells":"6","CD8_percent":"47","CD8_HLADR_CD38_percent":"9","Lymphocyte_count":"1516.2","Lymphocyte_percent":"39.9"}
},
{
"Subject ID":"GLD037",
"Sample ID":"37",
"Factors":{"Sample_Type":"Human","Lipodystrophy":"YES","HIV_status":"Positive","Antiviral_Treatment":"Yes"},
"Additional sample data":{"RAW_FILE_NAME":"37","Age":"57","Gender":"Male","Race":"White","Hispanic":"No","Height":"195","Weight":"89.9","BMI":"23.6","Adiponectin":"4.1","Glucose":"105","HDL":"43","Insulin":"8","LDL":"97","Leptin":"5","Triglycerides":"96","Fasting":"Yes","CD4_CD38_single_positive_cells":"60","CD4_count":"659","CD4_HLADR_single_positive_cells":"2","CD4_percent":"24","CD4_HLADR_CD38_percent":"2","CD8_CD38_single_positive_cells":"23","CD8_count":"871","CD8_HLADR_single_positive_cells":"3","CD8_percent":"37","CD8_HLADR_CD38_percent":"3","Lymphocyte_count":"2353","Lymphocyte_percent":"36.2"}
},
{
"Subject ID":"GLD040",
"Sample ID":"40",
"Factors":{"Sample_Type":"Human","Lipodystrophy":"NO","HIV_status":"Positive","Antiviral_Treatment":"Yes"},
"Additional sample data":{"RAW_FILE_NAME":"40","Age":"45","Gender":"Male","Race":"Black/African American","Hispanic":"No","Height":"153","Weight":"56","BMI":"23.9","Adiponectin":"14.4","Glucose":"98","HDL":"29","Insulin":"10","LDL":"86","Leptin":"1.9","Triglycerides":"57","Fasting":"Yes","CD4_CD38_single_positive_cells":"63","CD4_count":"431","CD4_HLADR_single_positive_cells":"3","CD4_percent":"12","CD4_HLADR_CD38_percent":"12","CD8_CD38_single_positive_cells":"81","CD8_count":"2084","CD8_HLADR_single_positive_cells":"-","CD8_percent":"58","CD8_HLADR_CD38_percent":"14","Lymphocyte_count":"3593.1","Lymphocyte_percent":"41.3"}
},
{
"Subject ID":"GLD045",
"Sample ID":"45",
"Factors":{"Sample_Type":"Human","Lipodystrophy":"YES","HIV_status":"Positive","Antiviral_Treatment":"Yes"},
"Additional sample data":{"RAW_FILE_NAME":"45","Age":"51","Gender":"Male","Race":"White","Hispanic":"No","Height":"178","Weight":"83.2","BMI":"26.3","Adiponectin":"4.3","Glucose":"103","HDL":"36","Insulin":"19","LDL":"74","Leptin":"11.6","Triglycerides":"67","Fasting":"Yes","CD4_CD38_single_positive_cells":"62","CD4_count":"908","CD4_HLADR_single_positive_cells":"1","CD4_percent":"25","CD4_HLADR_CD38_percent":"3","CD8_CD38_single_positive_cells":"61","CD8_count":"1743","CD8_HLADR_single_positive_cells":"-","CD8_percent":"48","CD8_HLADR_CD38_percent":"19","Lymphocyte_count":"3631.2","Lymphocyte_percent":"35.6"}
},
{
"Subject ID":"GLD055",
"Sample ID":"55",
"Factors":{"Sample_Type":"Human","Lipodystrophy":"YES","HIV_status":"Positive","Antiviral_Treatment":"Yes"},
"Additional sample data":{"RAW_FILE_NAME":"55","Age":"48","Gender":"Male","Race":"White","Hispanic":"No","Height":"179","Weight":"86.6","BMI":"27","Adiponectin":"4.7","Glucose":"89","HDL":"37","Insulin":"14","LDL":"145","Leptin":"21.9","Triglycerides":"178","Fasting":"Yes","CD4_CD38_single_positive_cells":"51","CD4_count":"550","CD4_HLADR_single_positive_cells":"1","CD4_percent":"17","CD4_HLADR_CD38_percent":"4","CD8_CD38_single_positive_cells":"5","CD8_count":"2007","CD8_HLADR_single_positive_cells":"1","CD8_percent":"62","CD8_HLADR_CD38_percent":"12","Lymphocyte_count":"3237","Lymphocyte_percent":"49.8"}
},
{
"Subject ID":"GLD057",
"Sample ID":"57",
"Factors":{"Sample_Type":"Human","Lipodystrophy":"NO","HIV_status":"Positive","Antiviral_Treatment":"Yes"},
"Additional sample data":{"RAW_FILE_NAME":"57","Age":"58","Gender":"Male","Race":"White","Hispanic":"No","Height":"176","Weight":"72.5","BMI":"23.4","Adiponectin":"11.4","Glucose":"116","HDL":"59","Insulin":"32","LDL":"97","Leptin":"4.2","Triglycerides":"178","Fasting":"Yes","CD4_CD38_single_positive_cells":"83","CD4_count":"240","CD4_HLADR_single_positive_cells":"1","CD4_percent":"26","CD4_HLADR_CD38_percent":"4","CD8_CD38_single_positive_cells":"44","CD8_count":"314","CD8_HLADR_single_positive_cells":"5","CD8_percent":"34","CD8_HLADR_CD38_percent":"12","Lymphocyte_count":"924","Lymphocyte_percent":"14"}
},
{
"Subject ID":"GLD069",
"Sample ID":"69",
"Factors":{"Sample_Type":"Human","Lipodystrophy":"YES","HIV_status":"Positive","Antiviral_Treatment":"Yes"},
"Additional sample data":{"RAW_FILE_NAME":"69","Age":"49","Gender":"Male","Race":"Black/African American","Hispanic":"No","Height":"188","Weight":"102","BMI":"28.9","Adiponectin":"4.5","Glucose":"109","HDL":"44","Insulin":"4","LDL":"102","Leptin":"3.5","Triglycerides":"74","Fasting":"Yes","CD4_CD38_single_positive_cells":"70","CD4_count":"1149.98","CD4_HLADR_single_positive_cells":"1","CD4_percent":"48","CD4_HLADR_CD38_percent":"2","CD8_CD38_single_positive_cells":"28","CD8_count":"742.7","CD8_HLADR_single_positive_cells":"3","CD8_percent":"31","CD8_HLADR_CD38_percent":"4","Lymphocyte_count":"2395.8","Lymphocyte_percent":"36.3"}
},
{
"Subject ID":"GLD072",
"Sample ID":"72",
"Factors":{"Sample_Type":"Human","Lipodystrophy":"YES","HIV_status":"Positive","Antiviral_Treatment":"Yes"},
"Additional sample data":{"RAW_FILE_NAME":"72","Age":"62","Gender":"Male","Race":"White","Hispanic":"No","Height":"176","Weight":"62.6","BMI":"20.2","Adiponectin":"5.1","Glucose":"94","HDL":"52","Insulin":"3","LDL":"44","Leptin":"2.3","Triglycerides":"146","Fasting":"Yes","CD4_CD38_single_positive_cells":"85","CD4_count":"686.91","CD4_HLADR_single_positive_cells":"-","CD4_percent":"57","CD4_HLADR_CD38_percent":"1","CD8_CD38_single_positive_cells":"23","CD8_count":"361.53","CD8_HLADR_single_positive_cells":"3","CD8_percent":"30","CD8_HLADR_CD38_percent":"9","Lymphocyte_count":"1205.1","Lymphocyte_percent":"30.9"}
},
{
"Subject ID":"GLD079",
"Sample ID":"79",
"Factors":{"Sample_Type":"Human","Lipodystrophy":"YES","HIV_status":"Positive","Antiviral_Treatment":"Yes"},
"Additional sample data":{"RAW_FILE_NAME":"79","Age":"63","Gender":"Male","Race":"White","Hispanic":"No","Height":"177.8","Weight":"72.8","BMI":"23","Adiponectin":"1.7","Glucose":"97","HDL":"26","Insulin":"10","LDL":"86","Leptin":"2.8","Triglycerides":"172","Fasting":"Yes","CD4_CD38_single_positive_cells":"32","CD4_count":"190","CD4_HLADR_single_positive_cells":"2","CD4_percent":"17","CD4_HLADR_CD38_percent":"5","CD8_CD38_single_positive_cells":"20","CD8_count":"358","CD8_HLADR_single_positive_cells":"3","CD8_percent":"32","CD8_HLADR_CD38_percent":"16","Lymphocyte_count":"1120","Lymphocyte_percent":"16"}
},
{
"Subject ID":"GLD080",
"Sample ID":"80",
"Factors":{"Sample_Type":"Human","Lipodystrophy":"YES","HIV_status":"Positive","Antiviral_Treatment":"Yes"},
"Additional sample data":{"RAW_FILE_NAME":"80","Age":"43","Gender":"Male","Race":"White","Hispanic":"No","Height":"172.7","Weight":"83.5","BMI":"28","Adiponectin":"3.4","Glucose":"89","HDL":"38","Insulin":"5","LDL":"100","Leptin":"5.1","Triglycerides":"103","Fasting":"Yes","CD4_CD38_single_positive_cells":"45","CD4_count":"922.32","CD4_HLADR_single_positive_cells":"2","CD4_percent":"28","CD4_HLADR_CD38_percent":"5","CD8_CD38_single_positive_cells":"41","CD8_count":"1976.4","CD8_HLADR_single_positive_cells":"10","CD8_percent":"60","CD8_HLADR_CD38_percent":"16","Lymphocyte_count":"3294","Lymphocyte_percent":"54"}
},
{
"Subject ID":"GLD104",
"Sample ID":"104",
"Factors":{"Sample_Type":"Human","Lipodystrophy":"YES","HIV_status":"Positive","Antiviral_Treatment":"Yes"},
"Additional sample data":{"RAW_FILE_NAME":"104","Age":"62","Gender":"Male","Race":"White","Hispanic":"No","Height":"167","Weight":"74.3","BMI":"26.6","Adiponectin":"3.4","Glucose":"121","HDL":"38","Insulin":"13","LDL":"91","Leptin":"4.6","Triglycerides":"97","Fasting":"Yes","CD4_CD38_single_positive_cells":"68","CD4_count":"1237","CD4_HLADR_single_positive_cells":"-","CD4_percent":"52","CD4_HLADR_CD38_percent":"1","CD8_CD38_single_positive_cells":"44","CD8_count":"666","CD8_HLADR_single_positive_cells":"-","CD8_percent":"28","CD8_HLADR_CD38_percent":"4","Lymphocyte_count":"2378.8","Lymphocyte_percent":"31.3"}
},
{
"Subject ID":"GLD106",
"Sample ID":"106",
"Factors":{"Sample_Type":"Human","Lipodystrophy":"YES","HIV_status":"Positive","Antiviral_Treatment":"Yes"},
"Additional sample data":{"RAW_FILE_NAME":"106","Age":"57","Gender":"Male","Race":"White","Hispanic":"No","Height":"183.5","Weight":"80.1","BMI":"23.8","Adiponectin":"5.6","Glucose":"89","HDL":"50","Insulin":"2","LDL":"81","Leptin":"1.9","Triglycerides":"77","Fasting":"Yes","CD4_CD38_single_positive_cells":"11","CD4_count":"599","CD4_HLADR_single_positive_cells":"2","CD4_percent":"26","CD4_HLADR_CD38_percent":"3","CD8_CD38_single_positive_cells":"12","CD8_count":"1360","CD8_HLADR_single_positive_cells":"6","CD8_percent":"59","CD8_HLADR_CD38_percent":"3","Lymphocyte_count":"2305","Lymphocyte_percent":"46.1"}
},
{
"Subject ID":"GLD112",
"Sample ID":"112",
"Factors":{"Sample_Type":"Human","Lipodystrophy":"NO","HIV_status":"Positive","Antiviral_Treatment":"Yes"},
"Additional sample data":{"RAW_FILE_NAME":"112","Age":"63","Gender":"Male","Race":"White","Hispanic":"No","Height":"184","Weight":"87.3","BMI":"25.8","Adiponectin":"4","Glucose":"95","HDL":"51","Insulin":"6","LDL":"73","Leptin":"6.3","Triglycerides":"51","Fasting":"Yes","CD4_CD38_single_positive_cells":"62","CD4_count":"385","CD4_HLADR_single_positive_cells":"2","CD4_percent":"33","CD4_HLADR_CD38_percent":"3","CD8_CD38_single_positive_cells":"45","CD8_count":"385","CD8_HLADR_single_positive_cells":"2","CD8_percent":"33","CD8_HLADR_CD38_percent":"6","Lymphocyte_count":"1165.8","Lymphocyte_percent":"18.5"}
},
{
"Subject ID":"GLD119",
"Sample ID":"119",
"Factors":{"Sample_Type":"Human","Lipodystrophy":"YES","HIV_status":"Positive","Antiviral_Treatment":"Yes"},
"Additional sample data":{"RAW_FILE_NAME":"119","Age":"64","Gender":"Male","Race":"White","Hispanic":"No","Height":"179","Weight":"90","BMI":"28.1","Adiponectin":"4.7","Glucose":"130","HDL":"35","Insulin":"112","LDL":"137","Leptin":"4.4","Triglycerides":"220","Fasting":"Yes","CD4_CD38_single_positive_cells":"61","CD4_count":"566","CD4_HLADR_single_positive_cells":"10","CD4_percent":"24","CD4_HLADR_CD38_percent":"9","CD8_CD38_single_positive_cells":"10","CD8_count":"944","CD8_HLADR_single_positive_cells":"14","CD8_percent":"40","CD8_HLADR_CD38_percent":"7","Lymphocyte_count":"2359.8","Lymphocyte_percent":"43.7"}
},
{
"Subject ID":"GLD128",
"Sample ID":"128",
"Factors":{"Sample_Type":"Human","Lipodystrophy":"NO","HIV_status":"Positive","Antiviral_Treatment":"Yes"},
"Additional sample data":{"RAW_FILE_NAME":"128","Age":"42","Gender":"Male","Race":"-","Hispanic":"No","Height":"188","Weight":"165","BMI":"21.2","Adiponectin":"10.2","Glucose":"97","HDL":"76","Insulin":"3","LDL":"89","Leptin":"3.6","Triglycerides":"127","Fasting":"Yes","CD4_CD38_single_positive_cells":"59","CD4_count":"594","CD4_HLADR_single_positive_cells":"2","CD4_percent":"37","CD4_HLADR_CD38_percent":"3","CD8_CD38_single_positive_cells":"20","CD8_count":"546","CD8_HLADR_single_positive_cells":"3","CD8_percent":"34","CD8_HLADR_CD38_percent":"4","Lymphocyte_count":"1606","Lymphocyte_percent":"30.3"}
},
{
"Subject ID":"GLD130",
"Sample ID":"130",
"Factors":{"Sample_Type":"Human","Lipodystrophy":"YES","HIV_status":"Positive","Antiviral_Treatment":"Yes"},
"Additional sample data":{"RAW_FILE_NAME":"130","Age":"65","Gender":"Male","Race":"White","Hispanic":"No","Height":"174","Weight":"73.5","BMI":"24.3","Adiponectin":"3.2","Glucose":"110","HDL":"29","Insulin":"30","LDL":"80","Leptin":"10","Triglycerides":"189","Fasting":"Yes","CD4_CD38_single_positive_cells":"68","CD4_count":"802","CD4_HLADR_single_positive_cells":"4","CD4_percent":"27","CD4_HLADR_CD38_percent":"6","CD8_CD38_single_positive_cells":"31","CD8_count":"1603","CD8_HLADR_single_positive_cells":"6","CD8_percent":"54","CD8_HLADR_CD38_percent":"10","Lymphocyte_count":"2968.4","Lymphocyte_percent":"36.2"}
},
{
"Subject ID":"GLD131",
"Sample ID":"131",
"Factors":{"Sample_Type":"Human","Lipodystrophy":"YES","HIV_status":"Positive","Antiviral_Treatment":"Yes"},
"Additional sample data":{"RAW_FILE_NAME":"131","Age":"54","Gender":"Male","Race":"White","Hispanic":"No","Height":"172","Weight":"87","BMI":"29.4","Adiponectin":"3.5","Glucose":"105","HDL":"36","Insulin":"16","LDL":"105","Leptin":"23.9","Triglycerides":"199","Fasting":"Yes","CD4_CD38_single_positive_cells":"56","CD4_count":"692","CD4_HLADR_single_positive_cells":"1","CD4_percent":"48","CD4_HLADR_CD38_percent":"5","CD8_CD38_single_positive_cells":"20","CD8_count":"274","CD8_HLADR_single_positive_cells":"6","CD8_percent":"19","CD8_HLADR_CD38_percent":"8","Lymphocyte_count":"1441.6","Lymphocyte_percent":"27.2"}
},
{
"Subject ID":"GLD132",
"Sample ID":"132",
"Factors":{"Sample_Type":"Human","Lipodystrophy":"YES","HIV_status":"Positive","Antiviral_Treatment":"Yes"},
"Additional sample data":{"RAW_FILE_NAME":"132","Age":"63","Gender":"Male","Race":"White","Hispanic":"No","Height":"182.9","Weight":"74.4","BMI":"22.3","Adiponectin":"8","Glucose":"105","HDL":"24","Insulin":"8","LDL":"51","Leptin":"4.8","Triglycerides":"79","Fasting":"Yes","CD4_CD38_single_positive_cells":"62","CD4_count":"955","CD4_HLADR_single_positive_cells":"-","CD4_percent":"39","CD4_HLADR_CD38_percent":"1","CD8_CD38_single_positive_cells":"21","CD8_count":"808","CD8_HLADR_single_positive_cells":"7","CD8_percent":"33","CD8_HLADR_CD38_percent":"5","Lymphocyte_count":"2448","Lymphocyte_percent":"15.3"}
},
{
"Subject ID":"GLD133",
"Sample ID":"133",
"Factors":{"Sample_Type":"Human","Lipodystrophy":"YES","HIV_status":"Positive","Antiviral_Treatment":"Yes"},
"Additional sample data":{"RAW_FILE_NAME":"133","Age":"61","Gender":"Male","Race":"White","Hispanic":"No","Height":"182","Weight":"92.9","BMI":"28","Adiponectin":"4.5","Glucose":"77","HDL":"18","Insulin":"17","LDL":"64","Leptin":"17.6","Triglycerides":"197","Fasting":"Yes","CD4_CD38_single_positive_cells":"58","CD4_count":"1013","CD4_HLADR_single_positive_cells":"1","CD4_percent":"22","CD4_HLADR_CD38_percent":"5","CD8_CD38_single_positive_cells":"38","CD8_count":"2441","CD8_HLADR_single_positive_cells":"1","CD8_percent":"53","CD8_HLADR_CD38_percent":"5","Lymphocyte_count":"4605.7","Lymphocyte_percent":"58.3"}
},
{
"Subject ID":"GLD145",
"Sample ID":"145",
"Factors":{"Sample_Type":"Human","Lipodystrophy":"YES","HIV_status":"Positive","Antiviral_Treatment":"Yes"},
"Additional sample data":{"RAW_FILE_NAME":"145","Age":"64","Gender":"Male","Race":"White","Hispanic":"No","Height":"173","Weight":"66.5","BMI":"22.3","Adiponectin":"3.2","Glucose":"99","HDL":"26","Insulin":"23","LDL":"53","Leptin":"5.5","Triglycerides":"321","Fasting":"Yes","CD4_CD38_single_positive_cells":"54","CD4_count":"562","CD4_HLADR_single_positive_cells":"1","CD4_percent":"36","CD4_HLADR_CD38_percent":"4","CD8_CD38_single_positive_cells":"8","CD8_count":"578","CD8_HLADR_single_positive_cells":"8","CD8_percent":"37","CD8_HLADR_CD38_percent":"5","Lymphocyte_count":"1561","Lymphocyte_percent":"22.3"}
},
{
"Subject ID":"GLD146",
"Sample ID":"146",
"Factors":{"Sample_Type":"Human","Lipodystrophy":"YES","HIV_status":"Positive","Antiviral_Treatment":"Yes"},
"Additional sample data":{"RAW_FILE_NAME":"146","Age":"65","Gender":"Male","Race":"White","Hispanic":"No","Height":"184","Weight":"87.3","BMI":"25.8","Adiponectin":"9.4","Glucose":"85","HDL":"63","Insulin":"6","LDL":"101","Leptin":"15.9","Triglycerides":"74","Fasting":"Yes","CD4_CD38_single_positive_cells":"60","CD4_count":"678","CD4_HLADR_single_positive_cells":"2","CD4_percent":"32","CD4_HLADR_CD38_percent":"5","CD8_CD38_single_positive_cells":"13","CD8_count":"720","CD8_HLADR_single_positive_cells":"1","CD8_percent":"34","CD8_HLADR_CD38_percent":"5","Lymphocyte_count":"2118.4","Lymphocyte_percent":"33.1"}
},
{
"Subject ID":"GLD152",
"Sample ID":"152",
"Factors":{"Sample_Type":"Human","Lipodystrophy":"YES","HIV_status":"Positive","Antiviral_Treatment":"Yes"},
"Additional sample data":{"RAW_FILE_NAME":"152","Age":"55","Gender":"Male","Race":"White","Hispanic":"Yes","Height":"177","Weight":"75.5","BMI":"24.1","Adiponectin":"7.8","Glucose":"92","HDL":"34","Insulin":"3","LDL":"81","Leptin":"6.5","Triglycerides":"256","Fasting":"Yes","CD4_CD38_single_positive_cells":"72","CD4_count":"311","CD4_HLADR_single_positive_cells":"1","CD4_percent":"15","CD4_HLADR_CD38_percent":"4","CD8_CD38_single_positive_cells":"59","CD8_count":"1120","CD8_HLADR_single_positive_cells":"1","CD8_percent":"54","CD8_HLADR_CD38_percent":"5","Lymphocyte_count":"2073.6","Lymphocyte_percent":"43.2"}
},
{
"Subject ID":"GLD156",
"Sample ID":"156",
"Factors":{"Sample_Type":"Human","Lipodystrophy":"YES","HIV_status":"Positive","Antiviral_Treatment":"Yes"},
"Additional sample data":{"RAW_FILE_NAME":"156","Age":"67","Gender":"Male","Race":"White","Hispanic":"No","Height":"170","Weight":"57.9","BMI":"20","Adiponectin":"3","Glucose":"101","HDL":"25","Insulin":"6","LDL":"36","Leptin":"3.4","Triglycerides":"187","Fasting":"Yes","CD4_CD38_single_positive_cells":"52","CD4_count":"359","CD4_HLADR_single_positive_cells":"1","CD4_percent":"30","CD4_HLADR_CD38_percent":"3","CD8_CD38_single_positive_cells":"77","CD8_count":"779","CD8_HLADR_single_positive_cells":"-","CD8_percent":"65","CD8_HLADR_CD38_percent":"13","Lymphocyte_count":"1197","Lymphocyte_percent":"9"}
},
{
"Subject ID":"GLD157",
"Sample ID":"157",
"Factors":{"Sample_Type":"Human","Lipodystrophy":"YES","HIV_status":"Positive","Antiviral_Treatment":"Yes"},
"Additional sample data":{"RAW_FILE_NAME":"157","Age":"66","Gender":"Male","Race":"White","Hispanic":"No","Height":"180","Weight":"71","BMI":"21.9","Adiponectin":"20.1","Glucose":"110","HDL":"49","Insulin":"4","LDL":"101","Leptin":"5.4","Triglycerides":"84","Fasting":"Yes","CD4_CD38_single_positive_cells":"38","CD4_count":"455","CD4_HLADR_single_positive_cells":"3","CD4_percent":"24","CD4_HLADR_CD38_percent":"4","CD8_CD38_single_positive_cells":"10","CD8_count":"1156","CD8_HLADR_single_positive_cells":"4","CD8_percent":"61","CD8_HLADR_CD38_percent":"2","Lymphocyte_count":"1895","Lymphocyte_percent":"37.9"}
},
{
"Subject ID":"GLD166",
"Sample ID":"166",
"Factors":{"Sample_Type":"Human","Lipodystrophy":"YES","HIV_status":"Positive","Antiviral_Treatment":"Yes"},
"Additional sample data":{"RAW_FILE_NAME":"166","Age":"59","Gender":"Male","Race":"White","Hispanic":"No","Height":"183","Weight":"98","BMI":"29.3","Adiponectin":"3.6","Glucose":"80","HDL":"44","Insulin":"4","LDL":"54","Leptin":"5.7","Triglycerides":"169","Fasting":"Yes","CD4_CD38_single_positive_cells":"33","CD4_count":"557","CD4_HLADR_single_positive_cells":"8","CD4_percent":"31","CD4_HLADR_CD38_percent":"8","CD8_CD38_single_positive_cells":"5","CD8_count":"1025","CD8_HLADR_single_positive_cells":"26","CD8_percent":"57","CD8_HLADR_CD38_percent":"5","Lymphocyte_count":"1798","Lymphocyte_percent":"29"}
},
{
"Subject ID":"GLD167",
"Sample ID":"167",
"Factors":{"Sample_Type":"Human","Lipodystrophy":"YES","HIV_status":"Positive","Antiviral_Treatment":"Yes"},
"Additional sample data":{"RAW_FILE_NAME":"167","Age":"48","Gender":"Male","Race":"Black/African American","Hispanic":"No","Height":"169","Weight":"55.3","BMI":"19.8","Adiponectin":"13.7","Glucose":"58","HDL":"40","Insulin":"5","LDL":"72","Leptin":"7","Triglycerides":"69","Fasting":"Yes","CD4_CD38_single_positive_cells":"27","CD4_count":"104","CD4_HLADR_single_positive_cells":"16","CD4_percent":"14","CD4_HLADR_CD38_percent":"24","CD8_CD38_single_positive_cells":"18","CD8_count":"467","CD8_HLADR_single_positive_cells":"17","CD8_percent":"63","CD8_HLADR_CD38_percent":"17","Lymphocyte_count":"742.4","Lymphocyte_percent":"25.6"}
},
{
"Subject ID":"DM002",
"Sample ID":"DM002",
"Factors":{"Sample_Type":"Human","Lipodystrophy":"NO","HIV_status":"Positive","Antiviral_Treatment":"Yes"},
"Additional sample data":{"RAW_FILE_NAME":"DM002","Age":"30","Gender":"Male","Race":"White","Hispanic":"No","Height":"186","Weight":"72.4","BMI":"21","Adiponectin":"4.4","Glucose":"93","HDL":"34","Insulin":"6","LDL":"60","Leptin":"6.8","Triglycerides":"110","Fasting":"Yes","CD4_CD38_single_positive_cells":"59","CD4_count":"573.21","CD4_HLADR_single_positive_cells":"2","CD4_percent":"27","CD4_HLADR_CD38_percent":"2","CD8_CD38_single_positive_cells":"11","CD8_count":"849.2","CD8_HLADR_single_positive_cells":"5","CD8_percent":"40","CD8_HLADR_CD38_percent":"5","Lymphocyte_count":"2123","Lymphocyte_percent":"38.6"}
},
{
"Subject ID":"DM003",
"Sample ID":"DM003",
"Factors":{"Sample_Type":"Human","Lipodystrophy":"NO","HIV_status":"Positive","Antiviral_Treatment":"Yes"},
"Additional sample data":{"RAW_FILE_NAME":"DM003","Age":"31","Gender":"Male","Race":"White","Hispanic":"No","Height":"-","Weight":"-","BMI":"-","Adiponectin":"3.4","Glucose":"88","HDL":"34","Insulin":"3","LDL":"81","Leptin":"2.7","Triglycerides":"81","Fasting":"Yes","CD4_CD38_single_positive_cells":"64","CD4_count":"486","CD4_HLADR_single_positive_cells":"-","CD4_percent":"28","CD4_HLADR_CD38_percent":"1","CD8_CD38_single_positive_cells":"27","CD8_count":"746","CD8_HLADR_single_positive_cells":"-","CD8_percent":"43","CD8_HLADR_CD38_percent":"2","Lymphocyte_count":"1734.6","Lymphocyte_percent":"41.3"}
},
{
"Subject ID":"DM019",
"Sample ID":"DM19",
"Factors":{"Sample_Type":"Human","Lipodystrophy":"NO","HIV_status":"Positive","Antiviral_Treatment":"Yes"},
"Additional sample data":{"RAW_FILE_NAME":"DM19","Age":"35","Gender":"Male","Race":"White","Hispanic":"No","Height":"177","Weight":"71.6","BMI":"22.9","Adiponectin":"6.1","Glucose":"98","HDL":"45","Insulin":"7","LDL":"128","Leptin":"6.2","Triglycerides":"119","Fasting":"Yes","CD4_CD38_single_positive_cells":"72","CD4_count":"1014","CD4_HLADR_single_positive_cells":"2","CD4_percent":"50","CD4_HLADR_CD38_percent":"6","CD8_CD38_single_positive_cells":"35","CD8_count":"466","CD8_HLADR_single_positive_cells":"5","CD8_percent":"23","CD8_HLADR_CD38_percent":"8","Lymphocyte_count":"2027.2","Lymphocyte_percent":"36.2"}
},
{
"Subject ID":"DM032",
"Sample ID":"DM032",
"Factors":{"Sample_Type":"Human","Lipodystrophy":"NO","HIV_status":"Positive","Antiviral_Treatment":"Yes"},
"Additional sample data":{"RAW_FILE_NAME":"DM032","Age":"46","Gender":"Male","Race":"White","Hispanic":"No","Height":"170","Weight":"62.7","BMI":"21.7","Adiponectin":"3.5","Glucose":"91","HDL":"37","Insulin":"3","LDL":"86","Leptin":"2.3","Triglycerides":"122","Fasting":"Yes","CD4_CD38_single_positive_cells":"91","CD4_count":"1216","CD4_HLADR_single_positive_cells":"-","CD4_percent":"57","CD4_HLADR_CD38_percent":"4","CD8_CD38_single_positive_cells":"45","CD8_count":"555","CD8_HLADR_single_positive_cells":"5","CD8_percent":"26","CD8_HLADR_CD38_percent":"15","Lymphocyte_count":"2133.6","Lymphocyte_percent":"38.1"}
},
{
"Subject ID":"DM034",
"Sample ID":"DM034",
"Factors":{"Sample_Type":"Human","Lipodystrophy":"NO","HIV_status":"Positive","Antiviral_Treatment":"Yes"},
"Additional sample data":{"RAW_FILE_NAME":"DM034","Age":"52","Gender":"Male","Race":"White","Hispanic":"No","Height":"177","Weight":"70.5","BMI":"22.5","Adiponectin":"11.4","Glucose":"92","HDL":"55","Insulin":"4","LDL":"94","Leptin":"5.4","Triglycerides":"93","Fasting":"Yes","CD4_CD38_single_positive_cells":"79","CD4_count":"753","CD4_HLADR_single_positive_cells":"1","CD4_percent":"47","CD4_HLADR_CD38_percent":"3","CD8_CD38_single_positive_cells":"42","CD8_count":"753","CD8_HLADR_single_positive_cells":"3","CD8_percent":"47","CD8_HLADR_CD38_percent":"7","Lymphocyte_count":"1601.6","Lymphocyte_percent":"36.4"}
},
{
"Subject ID":"DM036",
"Sample ID":"DM036",
"Factors":{"Sample_Type":"Human","Lipodystrophy":"NO","HIV_status":"Positive","Antiviral_Treatment":"Yes"},
"Additional sample data":{"RAW_FILE_NAME":"DM036","Age":"46","Gender":"Male","Race":"White","Hispanic":"No","Height":"184","Weight":"99","BMI":"29.2","Adiponectin":"5.3","Glucose":"92","HDL":"43","Insulin":"11","LDL":"113","Leptin":"50.3","Triglycerides":"202","Fasting":"Yes","CD4_CD38_single_positive_cells":"56","CD4_count":"1361","CD4_HLADR_single_positive_cells":"1","CD4_percent":"48","CD4_HLADR_CD38_percent":"1","CD8_CD38_single_positive_cells":"15","CD8_count":"1219","CD8_HLADR_single_positive_cells":"5","CD8_percent":"43","CD8_HLADR_CD38_percent":"3","Lymphocyte_count":"2835","Lymphocyte_percent":"40.5"}
},
{
"Subject ID":"DM052",
"Sample ID":"DM052",
"Factors":{"Sample_Type":"Human","Lipodystrophy":"NO","HIV_status":"Positive","Antiviral_Treatment":"Yes"},
"Additional sample data":{"RAW_FILE_NAME":"DM052","Age":"43","Gender":"Male","Race":"Black/African American","Hispanic":"No","Height":"172","Weight":"70.9","BMI":"24","Adiponectin":"7.7","Glucose":"80","HDL":"33","Insulin":"9","LDL":"42","Leptin":"5.1","Triglycerides":"52","Fasting":"Yes","CD4_CD38_single_positive_cells":"52","CD4_count":"331","CD4_HLADR_single_positive_cells":"2","CD4_percent":"22","CD4_HLADR_CD38_percent":"4","CD8_CD38_single_positive_cells":"35","CD8_count":"406","CD8_HLADR_single_positive_cells":"5","CD8_percent":"27","CD8_HLADR_CD38_percent":"7","Lymphocyte_count":"1505","Lymphocyte_percent":"35"}
},
{
"Subject ID":"113-W",
"Sample ID":"2_mouse",
"Factors":{"Sample_Type":"Humanized mouse","Lipodystrophy":"-","HIV_status":"Negative","Antiviral_Treatment":"No"},
"Additional sample data":{"RAW_FILE_NAME":"2_mouse","Age":"-","Gender":"-","Race":"-","Hispanic":"-","Height":"-","Weight":"-","BMI":"-","Adiponectin":"-","Glucose":"-","HDL":"-","Insulin":"-","LDL":"-","Leptin":"-","Triglycerides":"-","Fasting":"-","CD4_CD38_single_positive_cells":"-","CD4_count":"-","CD4_HLADR_single_positive_cells":"-","CD4_percent":"-","CD4_HLADR_CD38_percent":"-","CD8_CD38_single_positive_cells":"-","CD8_count":"-","CD8_HLADR_single_positive_cells":"-","CD8_percent":"-","CD8_HLADR_CD38_percent":"-","Lymphocyte_count":"-","Lymphocyte_percent":"-"}
},
{
"Subject ID":"DM19-W",
"Sample ID":"3_mouse",
"Factors":{"Sample_Type":"Humanized mouse","Lipodystrophy":"-","HIV_status":"Positive","Antiviral_Treatment":"Yes"},
"Additional sample data":{"RAW_FILE_NAME":"3_mouse","Age":"-","Gender":"-","Race":"-","Hispanic":"-","Height":"-","Weight":"-","BMI":"-","Adiponectin":"-","Glucose":"-","HDL":"-","Insulin":"-","LDL":"-","Leptin":"-","Triglycerides":"-","Fasting":"-","CD4_CD38_single_positive_cells":"-","CD4_count":"-","CD4_HLADR_single_positive_cells":"-","CD4_percent":"-","CD4_HLADR_CD38_percent":"-","CD8_CD38_single_positive_cells":"-","CD8_count":"-","CD8_HLADR_single_positive_cells":"-","CD8_percent":"-","CD8_HLADR_CD38_percent":"-","Lymphocyte_count":"-","Lymphocyte_percent":"-"}
},
{
"Subject ID":"74-W",
"Sample ID":"4_mouse",
"Factors":{"Sample_Type":"Humanized mouse","Lipodystrophy":"-","HIV_status":"Negative","Antiviral_Treatment":"No"},
"Additional sample data":{"RAW_FILE_NAME":"4_mouse","Age":"-","Gender":"-","Race":"-","Hispanic":"-","Height":"-","Weight":"-","BMI":"-","Adiponectin":"-","Glucose":"-","HDL":"-","Insulin":"-","LDL":"-","Leptin":"-","Triglycerides":"-","Fasting":"-","CD4_CD38_single_positive_cells":"-","CD4_count":"-","CD4_HLADR_single_positive_cells":"-","CD4_percent":"-","CD4_HLADR_CD38_percent":"-","CD8_CD38_single_positive_cells":"-","CD8_count":"-","CD8_HLADR_single_positive_cells":"-","CD8_percent":"-","CD8_HLADR_CD38_percent":"-","Lymphocyte_count":"-","Lymphocyte_percent":"-"}
},
{
"Subject ID":"117-W",
"Sample ID":"5_mouse",
"Factors":{"Sample_Type":"Humanized mouse","Lipodystrophy":"-","HIV_status":"Negative","Antiviral_Treatment":"No"},
"Additional sample data":{"RAW_FILE_NAME":"5_mouse","Age":"-","Gender":"-","Race":"-","Hispanic":"-","Height":"-","Weight":"-","BMI":"-","Adiponectin":"-","Glucose":"-","HDL":"-","Insulin":"-","LDL":"-","Leptin":"-","Triglycerides":"-","Fasting":"-","CD4_CD38_single_positive_cells":"-","CD4_count":"-","CD4_HLADR_single_positive_cells":"-","CD4_percent":"-","CD4_HLADR_CD38_percent":"-","CD8_CD38_single_positive_cells":"-","CD8_count":"-","CD8_HLADR_single_positive_cells":"-","CD8_percent":"-","CD8_HLADR_CD38_percent":"-","Lymphocyte_count":"-","Lymphocyte_percent":"-"}
},
{
"Subject ID":"118-W",
"Sample ID":"6_mouse",
"Factors":{"Sample_Type":"Humanized mouse","Lipodystrophy":"-","HIV_status":"Positive","Antiviral_Treatment":"No"},
"Additional sample data":{"RAW_FILE_NAME":"6_mouse","Age":"-","Gender":"-","Race":"-","Hispanic":"-","Height":"-","Weight":"-","BMI":"-","Adiponectin":"-","Glucose":"-","HDL":"-","Insulin":"-","LDL":"-","Leptin":"-","Triglycerides":"-","Fasting":"-","CD4_CD38_single_positive_cells":"-","CD4_count":"-","CD4_HLADR_single_positive_cells":"-","CD4_percent":"-","CD4_HLADR_CD38_percent":"-","CD8_CD38_single_positive_cells":"-","CD8_count":"-","CD8_HLADR_single_positive_cells":"-","CD8_percent":"-","CD8_HLADR_CD38_percent":"-","Lymphocyte_count":"-","Lymphocyte_percent":"-"}
},
{
"Subject ID":"DM9-W",
"Sample ID":"7_mouse",
"Factors":{"Sample_Type":"Humanized mouse","Lipodystrophy":"-","HIV_status":"Positive","Antiviral_Treatment":"Yes"},
"Additional sample data":{"RAW_FILE_NAME":"7_mouse","Age":"-","Gender":"-","Race":"-","Hispanic":"-","Height":"-","Weight":"-","BMI":"-","Adiponectin":"-","Glucose":"-","HDL":"-","Insulin":"-","LDL":"-","Leptin":"-","Triglycerides":"-","Fasting":"-","CD4_CD38_single_positive_cells":"-","CD4_count":"-","CD4_HLADR_single_positive_cells":"-","CD4_percent":"-","CD4_HLADR_CD38_percent":"-","CD8_CD38_single_positive_cells":"-","CD8_count":"-","CD8_HLADR_single_positive_cells":"-","CD8_percent":"-","CD8_HLADR_CD38_percent":"-","Lymphocyte_count":"-","Lymphocyte_percent":"-"}
},
{
"Subject ID":"DM8-W",
"Sample ID":"9_mouse",
"Factors":{"Sample_Type":"Humanized mouse","Lipodystrophy":"-","HIV_status":"Negative","Antiviral_Treatment":"No"},
"Additional sample data":{"RAW_FILE_NAME":"9_mouse","Age":"-","Gender":"-","Race":"-","Hispanic":"-","Height":"-","Weight":"-","BMI":"-","Adiponectin":"-","Glucose":"-","HDL":"-","Insulin":"-","LDL":"-","Leptin":"-","Triglycerides":"-","Fasting":"-","CD4_CD38_single_positive_cells":"-","CD4_count":"-","CD4_HLADR_single_positive_cells":"-","CD4_percent":"-","CD4_HLADR_CD38_percent":"-","CD8_CD38_single_positive_cells":"-","CD8_count":"-","CD8_HLADR_single_positive_cells":"-","CD8_percent":"-","CD8_HLADR_CD38_percent":"-","Lymphocyte_count":"-","Lymphocyte_percent":"-"}
},
{
"Subject ID":"73-W",
"Sample ID":"10_mouse",
"Factors":{"Sample_Type":"Humanized mouse","Lipodystrophy":"-","HIV_status":"Positive","Antiviral_Treatment":"No"},
"Additional sample data":{"RAW_FILE_NAME":"10_mouse","Age":"-","Gender":"-","Race":"-","Hispanic":"-","Height":"-","Weight":"-","BMI":"-","Adiponectin":"-","Glucose":"-","HDL":"-","Insulin":"-","LDL":"-","Leptin":"-","Triglycerides":"-","Fasting":"-","CD4_CD38_single_positive_cells":"-","CD4_count":"-","CD4_HLADR_single_positive_cells":"-","CD4_percent":"-","CD4_HLADR_CD38_percent":"-","CD8_CD38_single_positive_cells":"-","CD8_count":"-","CD8_HLADR_single_positive_cells":"-","CD8_percent":"-","CD8_HLADR_CD38_percent":"-","Lymphocyte_count":"-","Lymphocyte_percent":"-"}
},
{
"Subject ID":"PBS9.1-W",
"Sample ID":"1_mouse",
"Factors":{"Sample_Type":"PBS Control","Lipodystrophy":"-","HIV_status":"-","Antiviral_Treatment":"-"},
"Additional sample data":{"RAW_FILE_NAME":"1_mouse","Age":"-","Gender":"-","Race":"-","Hispanic":"-","Height":"-","Weight":"-","BMI":"-","Adiponectin":"-","Glucose":"-","HDL":"-","Insulin":"-","LDL":"-","Leptin":"-","Triglycerides":"-","Fasting":"-","CD4_CD38_single_positive_cells":"-","CD4_count":"-","CD4_HLADR_single_positive_cells":"-","CD4_percent":"-","CD4_HLADR_CD38_percent":"-","CD8_CD38_single_positive_cells":"-","CD8_count":"-","CD8_HLADR_single_positive_cells":"-","CD8_percent":"-","CD8_HLADR_CD38_percent":"-","Lymphocyte_count":"-","Lymphocyte_percent":"-"}
},
{
"Subject ID":"PBS9.2-W",
"Sample ID":"8_mouse",
"Factors":{"Sample_Type":"PBS Control","Lipodystrophy":"-","HIV_status":"-","Antiviral_Treatment":"-"},
"Additional sample data":{"RAW_FILE_NAME":"8_mouse","Age":"-","Gender":"-","Race":"-","Hispanic":"-","Height":"-","Weight":"-","BMI":"-","Adiponectin":"-","Glucose":"-","HDL":"-","Insulin":"-","LDL":"-","Leptin":"-","Triglycerides":"-","Fasting":"-","CD4_CD38_single_positive_cells":"-","CD4_count":"-","CD4_HLADR_single_positive_cells":"-","CD4_percent":"-","CD4_HLADR_CD38_percent":"-","CD8_CD38_single_positive_cells":"-","CD8_count":"-","CD8_HLADR_single_positive_cells":"-","CD8_percent":"-","CD8_HLADR_CD38_percent":"-","Lymphocyte_count":"-","Lymphocyte_percent":"-"}
}
],
"COLLECTION":{"COLLECTION_SUMMARY":"Whole blood was collected in sodium heparin vacutainers and centrifuged at 1700rpm for 10 minutes for plasma collection. Plasma was aliquoted into 1mL microcentrifuge tubes and stored at -80.","SAMPLE_TYPE":"Blood (plasma)","STORAGE_CONDITIONS":"-80℃"},

"TREATMENT":{"TREATMENT_SUMMARY":"n/a"},

"SAMPLEPREP":{"SAMPLEPREP_SUMMARY":"See uploaded file"},

"CHROMATOGRAPHY":{"CHROMATOGRAPHY_TYPE":"Reversed phase","INSTRUMENT_NAME":"Agilent 6545 QTOF","COLUMN_NAME":"Agilent Zorbax RRHD SB-C18 (100 x 2.1mm, 1.8um)"},

"ANALYSIS":{"ANALYSIS_TYPE":"MS"},

"MS":{"INSTRUMENT_NAME":"new","INSTRUMENT_TYPE":"QTOF","MS_TYPE":"ESI","ION_MODE":"POSITIVE","MS_COMMENTS":"attached","MS_RESULTS_FILE":"ST001750_AN002853_Results.txt UNITS:Abundance (Mass Spectral Counts) Has m/z:Neutral masses Has RT:Yes RT units:Minutes"}

}