#METABOLOMICS WORKBENCH sbhattacharya_20170606_122506 DATATRACK_ID:971 STUDY_ID:ST000620 ANALYSIS_ID:AN000952 PROJECT_ID:PR000453 VERSION 1 CREATED_ON June 15, 2017, 2:42 pm #PROJECT PR:PROJECT_TITLE DBA2J Mice Aqueous Humor and Trabecular Meshwork Sphingolipids PR:PROJECT_SUMMARY Identified the sphingolipid and ceramide species and their quantitative PR:PROJECT_SUMMARY differences between normotensive and hypertensive intraocular pressure states in PR:PROJECT_SUMMARY DBA/2J mouse aqueous humor (AH) and trabecular meshwork (TM). PR:INSTITUTE University of Miami PR:LAST_NAME Bhattacharya PR:FIRST_NAME Sanjoy PR:ADDRESS 1638 NW 10th Avenue, Miami, Florida, 33136, USA PR:EMAIL sbhattacharya@med.miami.edu PR:PHONE 3054824103 #STUDY ST:STUDY_TITLE Sphingolipid Analysis of hyper and normotensive DBA2J mice aqueous humor and ST:STUDY_TITLE trabecular meshwork ST:STUDY_SUMMARY To determine the differential profiles of sphingomyelin, sphingoid base, ST:STUDY_SUMMARY sphingoid base-1-phosphate, and ceramide and their quantitative differences ST:STUDY_SUMMARY between trabecular meshwork (TM) and aqueous humor (AH) derived from ST:STUDY_SUMMARY normotensive and hypertensive intraocular pressure states of DBA/2J mice. ST:INSTITUTE University of Miami ST:LAST_NAME Bhattacharya ST:FIRST_NAME Sanjoy ST:ADDRESS McKnight Vision Research Building, Bascom Palmer Eye Institute, University of ST:ADDRESS Miami Miller School of Medicine, 1638 NW 10th Avenue, Room 706A, Miami, Florida ST:ADDRESS 33136 ST:EMAIL SBhattacharya@med.miami.edu ST:PHONE 305-482-4103 #SUBJECT SU:SUBJECT_TYPE Mouse SU:SUBJECT_SPECIES Mus musculus SU:TAXONOMY_ID 10090 #SUBJECT_SAMPLE_FACTORS: SUBJECT(optional)[tab]SAMPLE[tab]FACTORS(NAME:VALUE pairs separated by |)[tab]Additional sample data SUBJECT_SAMPLE_FACTORS - 3M_FAH Phenotype:Normotensive Tissue Location=AH; Age (months)=3; Sex=F SUBJECT_SAMPLE_FACTORS - 3M_FTM Phenotype:Normotensive Tissue Location=TM; Age (months)=3; Sex=F SUBJECT_SAMPLE_FACTORS - 3M_MAH Phenotype:Normotensive Tissue Location=AH; Age (months)=3; Sex=M SUBJECT_SAMPLE_FACTORS - 3M_MTM Phenotype:Normotensive Tissue Location=TM; Age (months)=3; Sex=M SUBJECT_SAMPLE_FACTORS - 7.5M_FAH Phenotype:Normotensive Tissue Location=AH; Age (months)=7.5; Sex=F SUBJECT_SAMPLE_FACTORS - 7.5M_FTM Phenotype:Normotensive Tissue Location=TM; Age (months)=7.5; Sex=F SUBJECT_SAMPLE_FACTORS - 7.5M_MAH Phenotype:Normotensive Tissue Location=AH; Age (months)=7.5; Sex=M SUBJECT_SAMPLE_FACTORS - 7.5M_MTM Phenotype:Normotensive Tissue Location=TM; Age (months)=7.5; Sex=M SUBJECT_SAMPLE_FACTORS - 8-8.5M_FAH Phenotype:Hypertensive Tissue Location=AH; Age (months)=8-8.5; Sex=F SUBJECT_SAMPLE_FACTORS - 8-8.5M_FTM Phenotype:Hypertensive Tissue Location=TM; Age (months)=8-8.5; Sex=F SUBJECT_SAMPLE_FACTORS - 8-8.5M_MAH Phenotype:Hypertensive Tissue Location=AH; Age (months)=8-8.5; Sex=M SUBJECT_SAMPLE_FACTORS - 8-8.5M_MTM Phenotype:Hypertensive Tissue Location=TM; Age (months)=8-8.5; Sex=M SUBJECT_SAMPLE_FACTORS - 10M_FAH Phenotype:Hypertensive Tissue Location=AH; Age (months)=10; Sex=F SUBJECT_SAMPLE_FACTORS - 10M_FTM Phenotype:Hypertensive Tissue Location=TM; Age (months)=10; Sex=F SUBJECT_SAMPLE_FACTORS - 10M_MAH Phenotype:Hypertensive Tissue Location=AH; Age (months)=10; Sex=M SUBJECT_SAMPLE_FACTORS - 10M_MTM Phenotype:Hypertensive Tissue Location=TM; Age (months)=10; Sex=M SUBJECT_SAMPLE_FACTORS - 12M_FAH Phenotype:Hypertensive Tissue Location=AH; Age (months)=12; Sex=F SUBJECT_SAMPLE_FACTORS - 12M_FTM Phenotype:Hypertensive Tissue Location=TM; Age (months)=12; Sex=F SUBJECT_SAMPLE_FACTORS - 12M_MAH Phenotype:Hypertensive Tissue Location=AH; Age (months)=12; Sex=M SUBJECT_SAMPLE_FACTORS - 12M_MTM Phenotype:Hypertensive Tissue Location=TH; Age (months)=12; Sex=M #COLLECTION CO:COLLECTION_SUMMARY Breeding pairs of DBA/2J mice originally procured from The Jackson Laboratory CO:COLLECTION_SUMMARY (Bar Harbor, ME) were maintained at the animal facility/McKnight vivarium at CO:COLLECTION_SUMMARY University of Miami Miller School of Medicine. All animal protocols were CO:COLLECTION_SUMMARY reviewed and approved by Institutional Animal Care and Use Committee (IACUC) and CO:COLLECTION_SUMMARY in accordance with the ARVO statement for use of animals in ophthalmic and CO:COLLECTION_SUMMARY vision research. Mice gender and ages used are as indicated in individual CO:COLLECTION_SUMMARY experiments with an n=40 for each time point unless stated otherwise. IOP CO:COLLECTION_SUMMARY measurements were obtained using a TonoLab instrument (Colonial Medical CO:COLLECTION_SUMMARY Supplies, NH). Average IOP from two weeks of twice daily measurements were CO:COLLECTION_SUMMARY calculated. We considered ~3-7.5 month old mice as normotensive (IOP ≤15 mm of CO:COLLECTION_SUMMARY Hg) and ~8-12 month old mice as hypertensive when carefully measured IOP showed CO:COLLECTION_SUMMARY an IOP ≥18mm of Hg at every single measurement. For the normotensive group no CO:COLLECTION_SUMMARY single IOP measurement had been >17 mm of Hg and average IOP over two weeks of CO:COLLECTION_SUMMARY measurement had been ≤15 mm of Hg. At 8-9 months of age the IOP elevation in CO:COLLECTION_SUMMARY DBA/2J mice is asynchronous and thus any mice that showed an IOP <18 mm of Hg at CO:COLLECTION_SUMMARY any single point measurement was excluded from the study. Normotensive and CO:COLLECTION_SUMMARY hypertensive AH was sampled from the anterior chamber of DBA/2J mice by CO:COLLECTION_SUMMARY paracentesis via syringe (catalog no. 7635-01 Hamilton, Reno, Nevada) with a CO:COLLECTION_SUMMARY small 33 gauge removable needle (701RN, catalog no. 7803-05 Hamilton, Reno, CO:COLLECTION_SUMMARY Nevada), which is a well established procedure. The syringe and needle were CO:COLLECTION_SUMMARY rinsed with LC-MS grade water 5 times preceding and following extraction to CO:COLLECTION_SUMMARY flush out impurities. To ensure that samples are contamination free, in between CO:COLLECTION_SUMMARY the samples, the wash from a syringe was also evaluated using mass spectrometry. CO:COLLECTION_SUMMARY Prior to collection, mice were anesthetized with an injection (0.1ml) of CO:COLLECTION_SUMMARY ketamine (100mg/kg) and xylazine (9mg/kg) administered intraperitoneally. A drop CO:COLLECTION_SUMMARY of tetracaine hydrochloride ophthalmic solution, 0.5% (Bausch & Lomb, USA) was CO:COLLECTION_SUMMARY used to anesthetize the ocular surface just prior to sample collection. A total CO:COLLECTION_SUMMARY of ~1-2 μl of AH was collected per animal and used for lipid extraction. CO:COLLECTION_SUMMARY Surgical removal of TM samples after euthanasia followed established protocols. #TREATMENT TR:TREATMENT_SUMMARY No treatment was applied #SAMPLEPREP SP:SAMPLEPREP_SUMMARY AH and TM samples were subjected to lipid extraction using suitable modification SP:SAMPLEPREP_SUMMARY of the Bligh and Dryer method. All extractions were made without addition of any SP:SAMPLEPREP_SUMMARY extraneous ions such as lithium or acetate ions unless stated otherwise. Some SP:SAMPLEPREP_SUMMARY confirmatory additional experiments were performed, where 1mM LiCl or 1mM SP:SAMPLEPREP_SUMMARY ammonium acetate (for positive and negative ion mode analyses, respectively) was SP:SAMPLEPREP_SUMMARY added to the aliquot being analyzed just before analyses. The samples were dried SP:SAMPLEPREP_SUMMARY with a Speed-Vac and flushed with argon gas. Uniformity of extraction was SP:SAMPLEPREP_SUMMARY ensured with an added external standard (1, SP:SAMPLEPREP_SUMMARY 2-ditridecanoyl-snglycero-3-phosphocholine) during tissue homogenization. All SP:SAMPLEPREP_SUMMARY extractions and subsequent handling were done using glass vials to avoid SP:SAMPLEPREP_SUMMARY contaminating impurities. Extracted lipids were dried and resuspended in LC-MS SP:SAMPLEPREP_SUMMARY grade Acetonitrile:Isopropanol (1:1). #CHROMATOGRAPHY CH:CHROMATOGRAPHY_TYPE None (Direct infusion) CH:INSTRUMENT_NAME None CH:COLUMN_NAME none #ANALYSIS AN:ANALYSIS_TYPE MS #MS MS:MS_COMMENTS - MS:INSTRUMENT_NAME Thermo Quantiva Access Max MS:INSTRUMENT_TYPE Triple quadrupole MS:MS_TYPE ESI MS:ION_MODE UNSPECIFIED #MS_METABOLITE_DATA MS_METABOLITE_DATA:UNITS Peak Area MS_METABOLITE_DATA_START Samples 3M_FAH 3M_FTM 3M_MAH 3M_MTM 7.5M_FAH 7.5M_FTM 7.5M_MAH 7.5M_MTM 8-8.5M_FAH 8-8.5M_FTM 8-8.5M_MAH 8-8.5M_MTM 10M_FAH 10M_FTM 10M_MAH 10M_MTM 12M_FAH 12M_FTM 12M_MAH 12M_MTM Factors Phenotype:Normotensive Phenotype:Normotensive Phenotype:Normotensive Phenotype:Normotensive Phenotype:Normotensive Phenotype:Normotensive Phenotype:Normotensive Phenotype:Normotensive Phenotype:Hypertensive Phenotype:Hypertensive Phenotype:Hypertensive Phenotype:Hypertensive Phenotype:Hypertensive Phenotype:Hypertensive Phenotype:Hypertensive Phenotype:Hypertensive Phenotype:Hypertensive Phenotype:Hypertensive Phenotype:Hypertensive Phenotype:Hypertensive SM(d18:0/26:0) 30428.60168 4125.015211 9048.721133 2900.553559 SM(d17:1/26:1) 3837.329779 13695.71385 2742.538647 3617.584006 SM(d18:1/17:0) 992.4614763 2586.226448 2680.063769 1979.804149 Sphingosine-1-phosphate 80092.03664 19833.46614 5455.66959 117593.0812 52150.98272 138684.1656 5140.917534 14013.46792 611.8863373 41499.59747 15825.0176 45411.44369 2781.675018 84426.38332 67198.35075 1213.667035 38924.08897 Sphinganine-phosphate 86335.59822 15307.4342 8006.621895 49717.82173 34732.29739 2435.214452 17840.76558 118320.7677 292.0271169 11040.86847 4394.028686 8980.026753 18563.39083 7875.030744 6493.61665 Sphingosine 623946.7832 209661.7963 38802.90289 756419.5461 533098.1596 20645.15706 227923.5653 114309.9454 448352.831 1489623.873 5021.614278 656030.3486 15208.72811 69455.1573 417250.6039 237112.2969 26156.52337 29377.77458 328496.0842 Fumonisin C2 493983.8097 12663.32804 2785.378083 38897.37003 2080.976509 8866.670501 78001.38449 12767.42845 90290.7603 14033.54671 49675.7136 43733.1939 188999.3162 88138.43064 Fumonisin B2 239120.6883 111476.417 4701.177046 111809.7672 97365.66681 69934.23192 172735.6197 18181.72367 11570.30371 383703.0157 38549.71231 497472.6723 73709.46981 260054.5215 Sphingosine-1-phosphocholine 197732.8683 29521.13654 76076.51779 868885.3085 576853.1916 23529.77839 343325.9733 43302.61979 207399.1704 10338.42373 2097.088148 3578.878742 55066.65848 198959.4372 37647.03444 91362.87341 228313.5057 Penaresidin A 145683.2975 43957.58173 58239.97861 126299.0746 1016.325721 111343.3818 2204.954927 2468.884335 21695.80561 40515.57492 2478.736416 64910.53107 1568.920866 67189.12199 Fumonisin B4 122654.5113 109577.7961 14403.39227 57063.50137 604314.0215 272813.6741 56999.21732 244536.8007 66077.92583 160641.478 225530.2777 19073.50341 79311.14811 101020.7532 Micropine 112866.7076 288728.343 53792.73099 249875.3602 67513.64594 44958.29685 77863.61662 50164.83496 1421.316231 12813.67288 69550.2773 25514.51012 5221.198671 104587.9631 Fumonisin C1 93600.99771 321572.1313 38022.06128 5204.415238 207688.2038 215649.322 144554.4384 75427.60427 6512.835039 47715.33708 396364.6961 126802.2387 71946.56238 29099.96947 252713.4054 Aplidiasphingosine 90402.27192 14406.41805 5865.967069 4107.998028 17647.71151 6691.211869 85509.51746 6167.835771 47209.60058 7779.796513 9203.441945 51722.83517 20404.9239 Rhizochalinin D 57421.27423 15445.28611 2167.576022 130842.705 11778.3253 8920.283739 8285.550946 30832.19606 19252.81689 24163.53723 10274.66441 8317.707453 25123.13025 28416.70324 78201.68949 "N,N,N-trimethyl-sphingosine" 56358.68228 50258.22369 6656.621859 28191.59833 114610.402 243904.215 29426.60884 14648.94982 12434.17582 597974.0915 85048.56108 3380.641495 55299.26268 17313.95156 30941.2916 Penazetidine A 53365.33606 92854.18502 C17 Sphingosine 52757.90869 192440.375 9129.204735 49087.14348 12954.67635 117177.321 2567.864739 48962.26829 7744.183593 1989.280591 2946.49474 1168.173073 62321.67716 C16 Sphingosine-1-phosphate 50802.58204 6300.778588 2484.881641 29339.31874 192524.5687 3824.448788 14322.05955 5356.397268 16305.89754 96194.33041 1690.623407 5166.85481 1769.018724 2477.598642 21384.17084 8178.800562 C16 Sphinganine-1-phosphate 47762.70442 2527.523127 2086.004556 37911.96197 230164.8452 57431.98963 64998.62066 11504.20639 60995.5849 66123.19448 4395.927328 10885.50564 26083.79512 15856.53929 2262.370763 2372.162534 C19 Sphingosine-1-phosphate 45706.47172 13067.80325 10813.12085 33625.78092 43325.22504 12635.44567 52870.74404 5894.948749 117235.3676 177329.6261 24303.42175 6360.927568 78022.19104 12696.16226 56361.58202 "N,N-dimethylsphingosine" 37077.5645 56422.45587 24688.85995 12616.42925 39744.005 8854.695026 15279.10341 15384.39981 1775.200095 312536.4857 30766.86449 1209.881457 5610.757066 5058.82979 21159.09703 5409.782814 Leucettamol A 31924.57378 11634.81665 150751.6439 10278.12968 13816.74637 14346.59637 61561.24496 14313.27106 27232.35427 11197.87356 29181.28625 Sphinganine-1-phosphocholine 29623.89177 27700.23603 4089.087271 337090.5127 320482.2908 38953.46203 180626.8645 104750.6383 88685.37657 150233.5451 12116.91015 143255.822 198067.2311 39663.06581 6060.578415 143377.4903 Sulfamisterin 29132.2596 35682.84825 39494.57424 63492.55944 38125.80245 57147.52772 84308.36645 20036.07883 60117.2523 30132.89675 447.7650756 2507.894715 6947.721395 143466.7063 Hemsleyin imine A 28624.29563 6190.152135 50162.40981 3288.225543 64567.45229 143722.7561 31081.63367 4817.594582 Fumonisin C4 24179.56763 6604.381134 52894.03212 3424.112952 20608.35529 58422.28617 8287.428503 Fumonisin B1 23335.93667 114567.3088 113421.0123 2533.913378 3587.969704 14272.46323 389.3424058 9926.252991 28896.82012 C17 sphingosine-1-phosphocholine 22262.56049 8052.235774 40709.37912 8163.903916 109649.9805 904.941083 8828.575996 71334.73504 26262.96034 25813.70446 27119.18784 87936.96003 7039.217994 52091.98905 17826.63725 Halaminol A 21650.85562 2986.146418 5809.581037 21610.08525 44602.77229 163957.0675 160218.0142 71458.49965 26393.21511 21359.66254 212116.726 33294.08792 191423.5903 55593.61631 Plakoside A 19488.98863 22906.50303 22098.75044 76549.56999 "(4E,6E,d14:2) sphingosine" 17670.88732 119485.4792 741.5965548 51157.5955 19017.23588 231130.6426 62482.9632 236209.6222 68446.90559 3787.508022 16721.4653 30829.00977 165178.1826 292440.9697 558342.8213 879.1068207 154164.1975 292759.457 R-Dysidazirine 17544.54453 81042.10503 2618.308874 17087.69448 25362.97933 6282.951505 3783.600855 1014.617102 1782.297798 12034.06779 Scyphostatin A 16053.05603 24329.04588 13199.11689 154241.5053 138794.4815 259545.7794 49802.29598 6455.424372 32493.26745 49033.50497 285618.1597 11146.64586 17539.63319 Oceanalin A 15109.32988 11892.50663 14794.06432 14704.3513 130085.1552 C17 Sphingosine-1-phosphate 11342.44744 3394.493697 65320.99928 1064.544593 39712.37275 40228.88213 1379.022386 7739.247041 175272.6747 8296.571148 15857.23359 5787.340748 4920.020721 123632.7949 38531.82707 3203.498327 13842.93658 C17 Sphinganine-1-phosphate 10484.34679 11082.54673 12672.59381 1120.448221 1120.448221 5879.036658 82272.74736 57730.36394 12009.23392 96580.42053 6661.579438 37116.8366 47058.15731 19288.11833 3412.340849 C14 sphingosine 7091.469305 52879.74321 19026.07833 145279.5997 48161.65568 116864.545 61097.87665 67031.52229 107763.6704 3575.271183 2543.383794 9034.714274 101632.303 11142.52841 21963.56373 107457.9939 60156.75077 Termitomycesphin A 6359.031925 11479.42695 6803.983536 206710.8783 13315.51913 32272.94681 20985.02599 Sphinganine 1390.450818 54394.28953 34246.76575 142066.2248 28288.35197 35136.76569 71993.68065 49078.24929 3605.610499 70926.76746 39012.9518 13333.30753 Sphingofungin B 1017.131837 2668.559886 18234.20612 14262.2382 68214.49996 8146.182576 4063.717107 93599.40039 1431.046545 8298.953679 203.9932197 131303.7607 90636.83148 Dehydrophytosphingosine 824.7016698 77134.54177 58415.69814 2192.707897 370389.6009 4750.029124 48653.83435 25702.15271 181006.0191 108568.603 139712.2552 1422.448003 46780.26182 110353.7193 1431.454794 3136.493893 13391.46379 600.5086926 Xestoaminol C 462.1005861 55585.46606 4836.168911 40368.65891 4114.677612 13006.93963 836.2740613 34152.04752 24168.13673 2878.105909 632.4320445 26703.6135 6811.925019 183500.6566 17498.3045 Cer(d18:1/24:0) 123484.1753 2815.154298 8585.637831 68065.27345 25245.79191 4096.974184 8917.868488 2197.991655 6508.682321 12198.05104 10640.59135 Cer(d18:1/18:1(9Z)) 91387.08388 159003.1181 89237.21946 459944.9696 807989.099 609926.3376 129666.3182 371838.0866 2667989.935 4356475.698 4491959.311 1381423.865 3605434.059 701769.6908 2094019.274 722899.8548 2879862.661 1702461.191 Cer(d18:1/19:0) 52194.27593 13337.78006 3765.097441 46617.02135 136059.2435 4896.855567 2805.525093 4336.345158 31725.74478 511.1575664 1077.93207 7749.006501 5388.75905 43454.58359 1398.508287 1335.725208 Cer(d18:0/22:0) 34597.6408 13641.1124 6192.699953 62111.30165 7838.417823 8686.34323 4975.78811 6139.37991 32105.61546 2451.516842 4478.77872 38840.39371 33418.34869 13762.42592 Cer(d18:1/26:0) 32723.56025 3398.920346 722.3756872 5934.472621 10099.64029 363.28594 18734.789 1967.34652 Cer(t20:0/26:0(2OH)) 32232.2621 2435.21064 7109.236466 8769.662462 4066.627371 8784.828225 1426.947758 16285.7633 Cer(d18:2/15:0) 27685.05951 2030.161222 1983.820554 7928.503007 16828.24188 1261.54552 3999.044488 5452.26406 11756.25242 6465.821389 7862.386184 10472.44638 11383.89999 CerP(d18:1/2:0) 18774.609 688.4912252 2820.021512 4185.742216 74368.25055 10166.97894 19133.35481 13036.89904 780.9360707 4582.670725 9003.847188 1413.471935 890.7285732 Cer(d18:0/15:0) 16830.47847 16452.65821 15964.33265 16755.42361 1092.62505 206144.5789 7877.519921 23867.01438 30870.24606 12396.30839 48968.11091 97655.96692 24822.32747 CerP(d18:1/20:0) 15541.95431 3403.435729 3154.174655 1949.832724 3179.230368 16381.44476 Cer(d18:1/18:0) 10173.24372 9852.969465 7017.286759 17595.48802 37075.14601 2561.321328 15318.47475 34842.30716 582061.931 326164.3723 276253.7479 143251.6072 36784.27296 177334.752 34116.13645 109484.8274 65310.16896 Cer(d18:1/23:0) 10036.32398 3849.995891 4966.783404 1386.44637 1245.749032 8826.533117 7570.894099 4126.357137 Cer(d18:2/14:0) 9356.030109 2246.580359 5093.512405 4023.16841 27658.37252 9097.106064 5081.033085 1056.083919 10525.21959 43531.94111 7019.402329 5721.282545 11673.17419 Cer(d18:0/20:0(2OH)) 8625.418653 6391.308912 3538.404554 48658.80406 1311.675789 5905.65034 5132.966384 4303.453302 35215.0724 9896.702822 108200.3409 4533.116733 Cer(d20:0/26:0) 8502.907707 6174.298043 2608.408519 1913.811752 23720.8373 3133.768691 30140.84327 1178.321736 17877.08078 6502.735683 11728.83704 20234.50291 Cer(t18:0/24:0(2OH)) 7747.145264 1357.559053 3895.799353 1053.594477 2353.33881 13565.87696 17109.61737 7640.010161 17717.01146 Cer(d18:1/17:0) 7578.23043 33252.29165 34586.92333 2867.499335 11049.40943 19952.91265 3991.505202 26283.04222 9016.246513 10645.57948 1389.524248 Cer(d18:0/26:0) 7351.834254 2880.713032 15658.23145 12334.30114 2051.652959 3555.431625 9412.668575 1746.973474 57563.73737 60158.1799 19554.31551 Cer(d14:1(4E)/20:0(2OH)) 6803.094709 3057.457909 38275.17373 14512.22046 3255.748336 2278.877705 7840.219665 25492.27969 45948.29027 7654.21782 14382.30765 27650.54389 15096.04745 53047.39597 29452.61059 Cer(d18:1/20:0) 6766.239178 20378.4495 12108.32495 1951.331522 10061.44768 20701.35523 3347.341439 68717.45127 10112.91484 1802.948182 62773.35399 42700.45958 Cer(d18:0/h24:0) 5977.621294 2514.660496 157695.997 11324.44796 9521.356298 10416.38325 4063.142223 9442.069144 6445.518671 5019.331402 42280.23267 105251.5838 3291.281494 66261.70984 Cer(d18:1/24:1(15Z)) 5476.238709 7072.069531 6395.250408 4314.789263 10519.9442 23685.81377 21921.1666 Cer(d18:2/16:0) 5457.925617 53117.61531 5765.56681 68127.65219 18361.36638 98471.21467 31126.29749 12500.93935 67145.79497 16021.55739 63799.63117 8416.839127 9907.284227 71123.90539 21404.1725 "Cer(d14:2(4E,6E)/18:1(9Z))" 5292.526455 17867.49369 6182.222777 42462.58678 14484.14872 1296.134145 5079.044981 4469.987359 1079.284834 1034.895066 Cer(t18:0/26:0(2OH)) 5268.363524 7215.769972 1484.405394 1335.50395 5767.751734 2692.68754 11498.93343 975.2352739 1302.362695 Cer(t18:0/20:0(2OH)) 5068.897102 30518.62688 5044.941351 2136.816517 1117.638137 Cer(t18:0/16:0(2OH)) 4407.700079 15670.36955 2358.553474 11734.72104 8554.318159 17993.11497 21846.97176 45492.83022 36262.17601 1184.638641 18763.36763 5751.131932 1546.003158 CerP(d18:1/26:0) 4250.713428 7053.420379 5254.651296 978.7891819 2318.668819 21988.61323 15757.37942 5755.701885 CerP(d18:1/24:0) 3973.867087 63911.56336 8713.903584 16058.23196 2569.627219 3061.749263 27841.52682 10381.47632 42866.3158 34094.47163 19004.4803 163624.9035 2338.807796 59877.84956 7829.315833 Cer(d14:1(4E)/22:0(2OH)) 3692.340407 37948.23387 6785.509525 27448.07575 2889.798961 8625.008516 1741.028679 5230.723905 3571.301204 17844.37241 101015.9018 7829.037006 32589.30142 7977.4791 "Cer(d15:2(4E,6E)/22:0)" 3629.583968 582.9452576 4149.118201 176.0912675 21894.52761 1051.873251 14758.64009 9323.139547 2976.59626 2426.711978 5971.660484 3428.949467 75289.87419 1-O-cerotoyl-Cer(d18:1/16:0) 3442.90455 1468.242672 20566.31491 Cer(d18:2/20:1) 3160.206942 3243.025191 33558.64745 7728.220504 15307.34587 9345.586236 25650.42957 18936.55428 18442.18478 50795.14811 96221.95677 10092.11649 Cer(d18:0/24:0) 2746.296664 2291.176743 4217.531314 61088.67792 11089.06783 14233.21846 30915.99244 4828.365292 18662.73011 1792.731893 14343.73666 16504.72852 1-O-eicosanoyl-Cer(d18:1/16:0) 2654.358974 722.960184 3737.484773 1282.127244 13264.86811 64186.91185 Cer(d18:1/12:0) 1988.812668 2396.069672 877.9786673 9429.948321 29576.05053 3779.099045 10105.18436 40253.13939 9051.58228 564.2430672 4871.934634 735.3922553 767.0651 14289.471 6659.716455 8559.640218 CerP(d18:1/16:0) 1596.489499 2023.211227 5585.023744 1177.437877 4026.701212 6269.185147 7152.339057 5606.827758 2308.986092 56311.11101 14947.33503 26463.56813 Cer(d20:0/26:0(2OH)) 1509.819469 23739.92542 1037.108226 12456.99547 5294.723486 19581.01823 3744.173386 17456.04948 48415.16514 21080.65635 12232.33231 17302.02177 Cer(d18:0/20:0) 923.4168539 2342.988589 10243.01086 7272.609102 4474.96553 7292.972374 28701.62027 14882.52573 13329.08747 39886.71161 414.3954362 64280.47611 20036.85927 Cer(d18:1/22:0) 861.478764 6778.500849 1585.78617 1270.786965 1570.764806 724.8421284 8131.180002 1890.740318 SM(d18:2/18:1) 43168.36287 19257.7029 4720.963873 1718.191045 2825.262761 SM(d18:0/12:0) 34259.8738 3173.206914 2099.427961 2487.55428 141580.4923 10939.92021 7073.405758 16936.64747 8562.447129 193745.9172 11050.26972 SM(d18:2/22:1) 33359.76674 31557.30696 36257.82003 4263.421522 SM(d18:1/19:0) 10991.95814 1576.96283 86119.69014 SM(d16:1/24:1) 9374.531895 3113.042928 10322.20443 2136.08222 18433.99805 6530.918916 8563.382691 SM(d18:1/14:0) 7285.774605 2231.609959 1571.279659 7819.700982 1179.103377 SM(d18:0/22:0) 6499.251402 3678.12438 7127.808279 15659.04876 759.1186423 8557.040029 SM(d16:1/22:1) 3611.079656 10275.87225 2589.850608 2521.829922 4021.680974 SM(d18:1/26:1(17Z)) 1309.350416 29287.07082 19668.22355 SM(d18:0/17:0) 791.6622115 1619.567272 Calicogorgin A 158377.2718 "(4E,8E,9Me-d19:2)sphingosine" 136131.3649 3946.517899 88320.68749 224870.1084 72656.31956 77414.84469 7250.622459 71286.78483 148850.7364 19104.82924 31249.30007 140483.4764 163836.4073 196494.7642 69533.82489 135062.3292 Prosafrinine 93485.53065 1333.701016 8885.469105 63411.80751 29629.93921 737.2252529 1717.023689 11355.15796 414570.3246 20218.95691 Sphingofungin A 63803.10498 62980.18206 65625.71918 52253.61826 13045.97506 10842.16705 6015.993606 35314.70533 23470.81419 130768.3536 C16 Sphingosine 58386.47745 34799.25571 61510.3874 32645.49745 60911.96459 13391.59622 3226.045219 Sphingofungin E 42339.12605 73025.28082 17447.94655 17768.73837 3343.917324 15358.55082 38414.68061 Phytosphingosine 1-phosphate 39683.66378 40980.26704 2255.013774 7467.839403 45596.43893 830.5144263 13412.57763 1370.134367 78646.24316 9536.750861 4264.184112 1172.852042 7436.815588 1177.645358 18749.43581 "(4E,8E,10E-d18:3)sphingosine" 34552.52443 9554.173093 40267.40778 427097.2656 12075.78128 31116.28254 75922.28658 9745.582015 39446.8083 1887.45823 25264.53927 18218.94867 C16 Sphinganine 17271.05056 8163.434404 5714.235886 3002.434628 100878.809 43481.06963 1509.371138 39023.94411 Myriocin 2414.132443 66982.5859 6372.41047 23944.45668 114610.1581 133861.1308 37135.18365 2678.282022 38902.88099 47173.3463 6086.896351 24804.79907 4241.39338 7848.405393 Cer(d18:0/16:0) 542704.3081 182349.3028 156862.3836 118259.5109 161107.632 182505.5343 345517.2127 244587.5034 52209.43894 516963.8574 279580.7857 486455.3616 230650.525 560874.1843 58355.74184 174897.0222 Cer(d18:0/14:0) 404984.2725 4873.340375 63078.35846 54575.88245 15527.1338 174312.4672 132697.9682 310882.7765 8971.171713 171587.4181 51301.57651 52344.03205 48600.96125 171328.6761 35009.02966 32006.94293 Cer(d18:1/16:0) 121242.7154 29463.90248 69920.86114 9048.33649 29368.12234 67149.65084 185142.5517 580602.6786 52336.83491 498351.5194 352237.6378 157581.7212 695760.8672 199775.3427 78062.03249 197650.8273 386814.7608 Cer(d18:1/14:0) 25652.73296 46010.86758 24590.47211 6417.040495 5390.204559 75816.93251 3066.253953 9338.652804 59180.68063 8173.647083 26299.83875 1357.089659 526.8886366 49072.79297 Cer(d18:0/h17:0) 23097.16331 4397.729031 4125.405407 1404.494066 71898.33427 23204.11817 7690.633868 96950.83966 31563.20794 21623.30024 17933.3173 70637.14519 41953.58019 93898.56308 27407.87947 Cer(t18:0/22:0(2OH)) 21599.5934 5682.239568 9744.773746 797.3760281 3433.500562 14520.56733 12649.43037 6991.600421 7860.141953 Cer(d18:0/16:0(2OH)) 19900.07361 60034.44868 33226.60675 10835.22164 71451.59035 9027.981128 23010.62378 17434.91974 34133.01751 56152.09113 62395.32575 16519.75675 57253.87561 10763.11026 1-O-carboceroyl-Cer(d18:1/18:0) 19801.74498 9504.116015 5480.013654 15558.29668 4375.852424 11131.12938 5237.192274 2737.084659 5910.084239 CerP(d18:1/24:1(15Z)) 18448.95603 1743.963808 4405.412398 14065.79613 1436.52867 12412.98036 10235.72411 "Cer(d15:2(4E,6E)/20:0)" 16247.93095 40383.52643 5032.760878 24141.23924 6663.497812 712.6242274 46475.36669 259150.1581 28170.40186 17855.90064 2045.800201 3156.100441 14109.31215 Cer(d18:0/h26:0) 14408.51147 1855.655889 5345.845259 2177.070793 9794.611104 2166.710022 4335.785086 139407.1267 63692.34952 73681.09963 Cer(d16:1/17:0) 13348.57751 2810.859819 2701.672279 2507.156842 11149.73108 5872.840414 7501.90078 11317.06732 21214.65232 10921.95443 2195.383945 5018.207213 Cer(d18:2/18:1) 9520.548498 6449.539961 3067.37936 22865.44952 16894.14452 17469.5536 46588.47198 145898.8556 13106.16769 3662.599864 116043.6633 130402.661 33808.00642 CerP(d18:1/12:0) 7958.915726 7072.394297 1262.494985 8069.419968 Cer(d18:2/22:0) 5947.641295 3417.064803 13584.62191 440.9485633 2504.712137 29799.23876 2164.527353 11890.97356 Cer(d18:0/22:0(2OH)) 5393.926864 708.0366312 10842.94652 12397.33324 6232.371551 19349.50573 49132.13443 13856.95275 4575.371988 3516.327016 19821.96598 10352.42596 42258.15338 Cer(t18:0/18:0(2OH)) 4454.291637 1128.450628 11277.13827 9736.431909 14866.17563 10406.81746 13157.06087 61941.928 6166.153311 2078.034722 Cer(d16:1/23:0) 4287.418853 453.7604022 12474.29484 24071.54225 4327.5893 17750.39364 14956.76509 11271.26843 31100.91507 2862.638395 "Cer(d14:2(4E,6E)/16:0)" 3885.042872 989.8457054 12452.67281 1708.896486 5450.600324 3279.36887 4254.887827 94546.9271 17110.61845 1083.072649 29358.19683 1515.507738 5782.0327 18641.45985 "Cer(d14:2(4E,6E)/20:1(11Z)(2OH))" 3125.073137 52549.14332 Cer(d18:1/2:0) 2418.014419 8810.041255 526.3113543 1122.798039 525.2331821 613.0890901 Cer(d18:0/13:0) 1367.004609 83861.74354 24373.59736 2294.033294 1063.804366 79195.62848 8798.079269 20871.21343 5910.092294 344.8092899 1773.733887 33683.54805 565.3482147 5327.570331 51744.99198 Cer(d18:0/18:0) 978.7970259 6842.616024 6269.787185 756.8935179 10272.46642 3543.702483 11785.0029 4383.272453 17497.7645 4332.645992 14586.3049 99507.70196 1-O-stearoyl-Cer(d18:1/16:0) 467.2407655 1615.674391 1438.179595 3188.631351 5378.585368 3701.479184 SM(d18:1/24:1(15Z)) 111348.0682 2449.797217 2878.911791 18400.83961 SM(d18:2/15:0) 35943.06314 5149.963385 SM(d18:2/14:0) 10743.40015 16117.03106 4683.972244 SM(d18:2/20:1) 9834.138956 5499.882876 3748.760273 31320.09725 SM(d18:1/24:0) 7402.765211 2066.167494 683.1103131 12697.2473 SM(d18:1/12:0) 2316.62221 5298.974271 12702.80443 757.3979133 6318.334162 21192.58702 SM(d18:0/13:0) 1513.993592 4048.610515 Calyxinin 27816.26154 40320.79256 23922.5429 29322.64277 9813.061132 30439.65232 128300.3792 16291.12873 41800.08122 47764.93071 92782.67618 35411.69673 "(9Me,4E,8E,10E-d19:3)sphingosine" 8792.770242 82099.56981 22455.5432 7716.384493 61861.02018 3206.378258 16254.50975 38642.04709 2839.009798 Clavepictine B 4859.073563 34309.00168 42822.6492 3213.645261 36022.57651 15146.98843 10850.46429 2206.648114 22595.24151 25197.94126 Cer(d18:0/18:0(2OH)) 6320.121523 8744.863776 71165.99286 33605.43933 11624.52207 8221.72004 20644.38865 41385.16699 33556.73589 11876.36111 854.5695473 78607.89764 57238.44847 15367.99679 38119.33298 "Cer(d14:2(4E,6E)/20:1(11Z))" 3237.349869 16483.23695 2333.723358 1025.495316 475.3803246 15035.55143 89934.29382 8903.525959 1545.333922 37163.34954 1-O-carboceroyl-Cer(d18:1/16:0) 3083.062465 6256.19014 2790.18888 5742.393358 15477.10867 2122.340755 55567.5429 11510.72331 11052.81757 1473.766279 2362.608939 4824.988134 36071.6446 14394.95258 Cer(d14:1(4E)/20:1(11Z)(2OH)) 1391.754099 SM(d18:0/20:0) 11334.99572 2024.331362 2092.529411 SM(d18:1/18:0) 4289.190463 6524.592661 3792.05367 10892.80654 8035.172424 3194.713782 17951.34828 SM(d18:0/24:0) 4188.582733 5137.853467 1761.914922 7044.200534 SM(d18:1/16:0) 3376.653622 16704.06121 3821.968839 SM(d18:0/15:0) 3076.306244 5606.276484 SM(d18:2/21:0) 1185.536612 S-Antazirine 52410.0899 50627.72953 18159.8337 10309.86621 27027.30822 13431.02022 11595.64638 9514.004596 Pramanicin 37405.16818 1284.209417 14643.0912 9680.317393 C17 Sphinganine 19682.33963 34166.71178 24919.97696 3523.646707 54998.11176 117742.476 264502.714 22135.57322 16731.94147 13677.08938 Fumonisin A1 9617.398572 13918.4959 159617.9159 3796.333088 30110.4006 3-ketosphingosine 3427.949201 6872.103248 2869.201296 12812.95155 5531.130067 123717.0156 9980.486648 62405.70735 4523.049334 251165.3704 863368.8132 C18:1 Ceramide (d18:1/18:1(9Z)) 62752.55879 27207.26427 CerP(d18:1/26:1(17Z)) 47575.78089 4570.6833 1641.493243 5628.383357 18687.19684 Cer(d14:1(4E)/24:0(2OH)) 11467.21298 1086.381691 3003.887033 39770.38907 7297.768161 3904.436212 22933.58186 1558.467066 Cer(d18:2/20:0) 11009.8498 5079.958541 21086.4656 40795.89259 6171.178671 935.7137235 277643.3057 48899.23144 167590.3346 441868.9206 412478.9159 76693.14003 207587.6168 64156.73422 "Cer(d16:2(4E,6E)/24:0(2OH))" 8079.02901 1057.852606 Cer(d18:2/21:0) 6745.585455 10878.57389 28821.22837 591.2898647 3216.158063 1324.865021 2007.704693 4573.822505 8971.10803 13323.81083 30963.95893 CerP(d18:1/22:0) 6364.028761 6019.260269 10402.66149 7428.565828 9922.866011 5537.449871 2661.969124 18228.32018 SM(d17:1/24:1) 1759.336066 4486.721676 Sphingosine (d18:1) 119961.0688 11187.79136 7498.213833 69687.89273 Phytosphingosine 29546.40025 682.8316766 11702.47458 9847.058408 22179.31124 3088.437093 17430.19814 CerP(d18:1/18:0) 7653.882402 6444.486567 4044.351394 2762.783657 1568.482318 5014.680675 3143.323966 2011.077546 36045.56549 Cer(d14:1(4E)/26:0(2OH)) 3278.211201 8605.318504 2651.619134 20956.62899 1164.561351 307471.732 14010.67223 49980.83133 23922.68937 Cer(d18:1/26:1(17Z)) 3230.883513 25655.75795 970.3958204 6072.103242 "Cer(d14:2(4E,6E)/22:1(13Z)(2OH))" 2950.628205 1-O-behenoyl-Cer(d18:1/16:0) 1464.396042 2341.997974 1789.414234 3938.723171 4338.916748 1785.543908 CerP(d18:1/8:0) 1192.849519 5081.730718 4606.377424 SM(d18:1/26:0) 8210.538887 6125.128774 3081.216914 SM(d18:1/18:1(9Z)) 3873.868776 4377.06004 3625.728995 SM(d16:1/23:0) 2039.259904 3843.605608 1-O-tricosanoyl-Cer(d18:1/18:0) 32842.19801 11828.95023 5938.838907 1-O-lignoceroyl-Cer(d18:1/16:0) 16049.06019 5382.000676 4669.373444 4577.974378 1-O-myristoyl-Cer(d18:1/16:0) 6881.735279 3213.55339 2811.790298 1164.229942 1511.386198 23027.08853 118472.9699 18833.40171 4432.156571 419.9941161 SM(d16:1/17:0) 4336.935184 1-O-cerotoyl-Cer(d18:1/18:0) 7054.519052 28280.10225 1-O-tricosanoyl-Cer(d18:1/16:0) 5164.024212 1932.677107 1676.517956 7337.0095 17184.25094 1305.244665 "Cer(d15:2(4E,6E)/20:0(2OH))" 1705.932032 1-O-palmitoyl-Cer(d18:1/16:0) 18721.33346 3613.929999 CerP(d18:0/16:0) 1052.10868 444.2898764 Cer(d18:1/25:0) 408.7517635 35636.23988 17170.60825 30042.61416 4651.876426 3802.198426 4680.183957 10599.21578 SM(d18:1/25:0) 3724.528476 33402.87722 419.2806236 Prosopinine 17421.09809 Cer(d18:2/23:0) 2598.967939 3564.398341 1563.757699 5194.164869 4319.182198 2212.857441 15458.2355 SM(d16:1/18:1) 52854.76166 1927.480191 8228.465691 4421.636207 SM(d18:0/16:0) 2719.926565 3013.713108 SM(d18:2/24:1) 2628.409283 33810.19807 4693.900165 1993.258539 10737.40116 SM(d18:0/18:0) 1160.365537 9217.2735 7435.540663 600.1111893 Obscuraminol A 2681.301307 1111.12167 2143.961617 2229.114369 47940.28201 SM(d18:1/22:0) 3975.362741 6036.547101 2059.154096 14302.0887 4397.76314 132334.4943 SM(d16:1/25:0) 2230.293777 640.3421386 SM(d18:0/14:0) 1708.677858 Cer(d18:0/17:0) 6926.570482 CerP(d18:1/14:0) 13534.64541 SM(d18:1/20:0) 1889.245058 Cer(d14:1(4E)/22:1(13Z)(2OH)) 44870.94174 "Cer(d14:2(4E,6E)/24:0(2OH))" 619.0972161 MS_METABOLITE_DATA_END #METABOLITES METABOLITES_START metabolite_name M/Z "(4E,6E,d14:2) sphingosine" 242.2142 "(4E,8E,10E-d18:3)sphingosine" 296.2611 "(4E,8E,9Me-d19:2)sphingosine" 312.2924 "(9Me,4E,8E,10E-d19:3)sphingosine" 310.2768 1-O-behenoyl-Cer(d18:1/16:0) 858.8257 1-O-carboceroyl-Cer(d18:1/16:0) 900.8726 1-O-carboceroyl-Cer(d18:1/18:0) 970.9509 1-O-cerotoyl-Cer(d18:1/16:0) 914.8883 1-O-cerotoyl-Cer(d18:1/18:0) 942.9196 1-O-eicosanoyl-Cer(d18:1/16:0) 830.7944 1-O-lignoceroyl-Cer(d18:1/16:0) 886.857 1-O-myristoyl-Cer(d18:1/16:0) 746.7005 1-O-palmitoyl-Cer(d18:1/16:0) 774.7318 1-O-stearoyl-Cer(d18:1/16:0) 802.7631 1-O-tricosanoyl-Cer(d18:1/16:0) 872.8413 1-O-tricosanoyl-Cer(d18:1/18:0) 998.9822 3-ketosphingosine 298.2768 Aplidiasphingosine 370.3343 C14 sphingosine 244.2298 C16 Sphinganine 274.2768 C16 Sphinganine-1-phosphate 352.2231 C16 Sphingosine 272.2611 C16 Sphingosine-1-phosphate 350.2075 C17 Sphinganine 288.2924 C17 Sphinganine-1-phosphate 366.2388 C17 Sphingosine 286.2768 C17 Sphingosine-1-phosphate 364.2231 C17 sphingosine-1-phosphocholine 451.3323 C18:1 Ceramide (d18:1/18:1(9Z)) 562.418 C19 Sphingosine-1-phosphate 392.2544 Calicogorgin A 380.3186 Calyxinin 487.4497 Cer(d14:1(4E)/20:0(2OH)) 552.497 Cer(d14:1(4E)/20:1(11Z)(2OH)) 550.4814 Cer(d14:1(4E)/22:0(2OH)) 580.5283 Cer(d14:1(4E)/22:1(13Z)(2OH)) 578.5127 Cer(d14:1(4E)/24:0(2OH)) 608.5596 Cer(d14:1(4E)/26:0(2OH)) 636.5909 "Cer(d14:2(4E,6E)/16:0)" 478.4238 "Cer(d14:2(4E,6E)/18:1(9Z))" 504.4395 "Cer(d14:2(4E,6E)/20:1(11Z)(2OH))" 548.4657 "Cer(d14:2(4E,6E)/20:1(11Z))" 532.4708 "Cer(d14:2(4E,6E)/22:1(13Z)(2OH))" 576.497 "Cer(d14:2(4E,6E)/24:0(2OH))" 606.544 "Cer(d15:2(4E,6E)/20:0(2OH))" 564.497 "Cer(d15:2(4E,6E)/20:0)" 548.5021 "Cer(d15:2(4E,6E)/22:0)" 576.5334 Cer(d16:1/17:0) 522.4864 Cer(d16:1/23:0) 606.5803 "Cer(d16:2(4E,6E)/24:0(2OH))" 634.5753 Cer(d18:0/13:0) 496.4708 Cer(d18:0/14:0) 510.4864 Cer(d18:0/15:0) 524.5021 Cer(d18:0/16:0(2OH)) 554.5127 Cer(d18:0/16:0) 538.5177 Cer(d18:0/17:0) 552.5334 Cer(d18:0/18:0(2OH)) 582.544 Cer(d18:0/18:0) 566.549 Cer(d18:0/20:0(2OH)) 610.5753 Cer(d18:0/20:0) 594.5803 Cer(d18:0/22:0(2OH)) 638.6066 Cer(d18:0/22:0) 622.6116 Cer(d18:0/24:0) 650.6429 Cer(d18:0/26:0) 678.6742 Cer(d18:0/h17:0) 568.5283 Cer(d18:0/h24:0) 666.6379 Cer(d18:0/h26:0) 694.6692 Cer(d18:1/12:0) 480.4395 Cer(d18:1/14:0) 508.4708 Cer(d18:1/16:0) 536.5021 Cer(d18:1/17:0) 550.5177 Cer(d18:1/18:0) 564.5334 Cer(d18:1/18:1(9Z)) 562.5177 Cer(d18:1/19:0) 578.549 Cer(d18:1/2:0) 340.283 Cer(d18:1/20:0) 592.5647 Cer(d18:1/22:0) 620.596 Cer(d18:1/23:0) 634.6116 Cer(d18:1/24:0) 648.6273 Cer(d18:1/24:1(15Z)) 646.6116 Cer(d18:1/25:0) 662.6429 Cer(d18:1/26:0) 676.6586 Cer(d18:1/26:1(17Z)) 674.6429 Cer(d18:2/14:0) 506.4551 Cer(d18:2/15:0) 520.4708 Cer(d18:2/16:0) 534.4864 Cer(d18:2/18:1) 560.5021 Cer(d18:2/20:0) 590.549 Cer(d18:2/20:1) 588.5334 Cer(d18:2/21:0) 604.5647 Cer(d18:2/22:0) 618.5803 Cer(d18:2/23:0) 632.596 Cer(d20:0/26:0(2OH)) 722.7005 Cer(d20:0/26:0) 706.7055 Cer(t18:0/16:0(2OH)) 570.5076 Cer(t18:0/18:0(2OH)) 598.5389 Cer(t18:0/20:0(2OH)) 626.5702 Cer(t18:0/22:0(2OH)) 654.6015 Cer(t18:0/24:0(2OH)) 682.6328 Cer(t18:0/26:0(2OH)) 710.6641 Cer(t20:0/26:0(2OH)) 738.6954 CerP(d18:0/16:0) 618.4841 CerP(d18:1/12:0) 560.4058 CerP(d18:1/14:0) 588.4371 CerP(d18:1/16:0) 616.4684 CerP(d18:1/18:0) 644.4997 CerP(d18:1/2:0) 420.2493 CerP(d18:1/20:0) 672.531 CerP(d18:1/22:0) 700.5623 CerP(d18:1/24:0) 728.5936 CerP(d18:1/24:1(15Z)) 726.578 CerP(d18:1/26:0) 756.6249 CerP(d18:1/26:1(17Z)) 754.6093 CerP(d18:1/8:0) 504.3432 Clavepictine B 306.2819 Dehydrophytosphingosine 316.2873 Fumonisin A1 764.409 Fumonisin B1 722.3985 Fumonisin B2 706.4036 Fumonisin B4 690.4086 Fumonisin C1 708.3828 Fumonisin C2 692.3879 Fumonisin C4 676.393 Halaminol A 228.2349 Hemsleyin imine A 606.5847 Leucettamol A 473.4129 Micropine 266.2142 Myriocin 402.2877 "N,N,N-trimethyl-sphingosine" 343.3472 "N,N-dimethylsphingosine" 328.3237 Obscuraminol A 278.2506 Oceanalin A 737.5338 Penaresidin A 330.303 Penazetidine A 370.3707 Phytosphingosine 318.303 Phytosphingosine 1-phosphate 396.2493 Plakoside A 948.7889 Pramanicin 370.2251 Prosafrinine 284.2611 Prosopinine 288.256 R-Dysidazirine 308.2611 Rhizochalinin D 647.5232 S-Antazirine 434.0352 Scyphostatin A 512.3398 SM(d16:1/17:0) 689.5619 SM(d16:1/18:1) 701.5619 SM(d16:1/22:1) 757.6245 SM(d16:1/23:0) 773.6558 SM(d16:1/24:1) 785.6558 SM(d16:1/25:0) 801.6871 SM(d17:1/24:1) 799.6715 SM(d17:1/26:1) 827.7028 SM(d18:0/12:0) 649.5306 SM(d18:0/13:0) 663.5463 SM(d18:0/14:0) 677.5619 SM(d18:0/15:0) 691.5776 SM(d18:0/16:0) 705.5932 SM(d18:0/17:0) 719.6089 SM(d18:0/18:0) 733.6245 SM(d18:0/20:0) 761.6558 SM(d18:0/22:0) 789.6871 SM(d18:0/24:0) 817.7184 SM(d18:0/26:0) 845.7497 SM(d18:1/12:0) 647.515 SM(d18:1/14:0) 675.5463 SM(d18:1/16:0) 703.5776 SM(d18:1/17:0) 717.5932 SM(d18:1/18:0) 731.6089 SM(d18:1/18:1(9Z)) 729.5932 SM(d18:1/19:0) 745.6245 SM(d18:1/20:0) 759.6402 SM(d18:1/22:0) 787.6715 SM(d18:1/24:0) 815.7028 SM(d18:1/24:1(15Z)) 813.6871 SM(d18:1/25:0) 829.7184 SM(d18:1/26:0) 843.7341 SM(d18:1/26:1(17Z)) 841.7184 SM(d18:2/14:0) 673.5306 SM(d18:2/15:0) 687.5463 SM(d18:2/18:1) 727.5776 SM(d18:2/20:1) 755.6089 SM(d18:2/21:0) 771.6402 SM(d18:2/22:1) 783.6402 SM(d18:2/24:1) 811.6715 Sphinganine 302.3081 Sphinganine-1-phosphocholine 467.3636 Sphinganine-phosphate 380.2544 Sphingofungin A 432.3095 Sphingofungin B 390.2877 Sphingofungin E 418.2827 Sphingosine 300.2924 Sphingosine (d18:1) 300.392 Sphingosine-1-phosphate 378.2388 Sphingosine-1-phosphocholine 465.3479 Sulfamisterin 462.2159 Termitomycesphin A 744.5648 Xestoaminol C 230.2506 METABOLITES_END #END