#METABOLOMICS WORKBENCH michaelsa93_20170628_124602 DATATRACK_ID:1105 STUDY_ID:ST000659 ANALYSIS_ID:AN001006 PROJECT_ID:PR000463
VERSION             	1
CREATED_ON             	June 29, 2017, 11:33 am
#PROJECT
PR:PROJECT_TITLE                 	Changes in metabolites and lipid mediators associated with supervised exercise
PR:PROJECT_TITLE                 	training for peripheral artery disease
PR:PROJECT_SUMMARY               	Peripheral artery disease (PAD) is a leading cause of cardiovascular related
PR:PROJECT_SUMMARY               	morbidity and mortality, affecting over 8.5 million men and women in the United
PR:PROJECT_SUMMARY               	States and greater than 200 million individuals worldwide. The mainstay of
PR:PROJECT_SUMMARY               	treatment to improve lower limb symptoms is supervised walking therapy, which
PR:PROJECT_SUMMARY               	does not affect plaque morphology or alter conduit artery blood flow, but rather
PR:PROJECT_SUMMARY               	ameliorates endothelial dysfunction, enhances skeletal muscle metabolism and
PR:PROJECT_SUMMARY               	mitochondrial function, and suppresses inflammatory activation. In this pilot
PR:PROJECT_SUMMARY               	feasibility project we will employ metabolic and lipidomic techniques to measure
PR:PROJECT_SUMMARY               	the effects of supervised exercise therapy on primary metabolism, complex
PR:PROJECT_SUMMARY               	lipids, and lipid mediators, and correlate these effects with individual,
PR:PROJECT_SUMMARY               	subject-level measures of the response to exercise therapy among subjects with
PR:PROJECT_SUMMARY               	PAD. The overarching theme of this work is to identify metabolites, complex
PR:PROJECT_SUMMARY               	lipids, and lipid mediators that are associated with the inter-individual
PR:PROJECT_SUMMARY               	variability in the response of subjects with PAD to supervised exercise therapy.
PR:PROJECT_SUMMARY               	This knowledge will significantly enhance our understanding of the
PR:PROJECT_SUMMARY               	pathophysiology of lower extremity symptoms in PAD, as well as the manner in
PR:PROJECT_SUMMARY               	which supervised exercise therapy improves walking intolerance. It will identify
PR:PROJECT_SUMMARY               	novel therapeutic targets and pathways for pharmacologic manipulation in the
PR:PROJECT_SUMMARY               	treatment of PAD. Aside from having the potential to generate multiple
PR:PROJECT_SUMMARY               	high-impact publications, it will serve as the basis for a planned NIH R01
PR:PROJECT_SUMMARY               	submission by the PI at the conclusion of the award period.
PR:INSTITUTE                     	University of Pennsylvania
PR:DEPARTMENT                    	Surgery, Perelman School of Medicine
PR:LAST_NAME                     	Scott
PR:FIRST_NAME                    	Damrauer
PR:ADDRESS                       	3400 Spruce Street, 4 Silverstein Philadelphia, PA 19104
PR:EMAIL                         	Scott.Damrauer@uphs.upenn.edu
PR:PHONE                         	215-615-1698
#STUDY
ST:STUDY_TITLE                   	Changes in metabolites and lipid mediators associated with supervised exercise
ST:STUDY_TITLE                   	training for peripheral
ST:STUDY_TYPE                    	Timecourse
ST:STUDY_SUMMARY                 	Peripheral artery disease (PAD) is a leading cause of cardiovascular related
ST:STUDY_SUMMARY                 	morbidity and mortality, affecting over 8.5 million men and women in the United
ST:STUDY_SUMMARY                 	States and greater than 200 million individuals worldwide. The mainstay of
ST:STUDY_SUMMARY                 	treatment to improve lower limb symptoms is supervised walking therapy, which
ST:STUDY_SUMMARY                 	does not affect plaque morphology or alter conduit artery blood flow, but rather
ST:STUDY_SUMMARY                 	ameliorates endothelial dysfunction, enhances skeletal muscle metabolism and
ST:STUDY_SUMMARY                 	mitochondrial function, and suppresses inflammatory activation. In this pilot
ST:STUDY_SUMMARY                 	feasibility project we will employ metabolic and lipidomic techniques to measure
ST:STUDY_SUMMARY                 	the effects of supervised exercise therapy on primary metabolism, complex
ST:STUDY_SUMMARY                 	lipids, and lipid mediators, and correlate these effects with individual,
ST:STUDY_SUMMARY                 	subject-level measures of the response to exercise therapy among subjects with
ST:STUDY_SUMMARY                 	PAD. The overarching theme of this work is to identify metabolites, complex
ST:STUDY_SUMMARY                 	lipids, and lipid mediators that are associated with the inter-individual
ST:STUDY_SUMMARY                 	variability in the response of subjects with PAD to supervised exercise therapy.
ST:STUDY_SUMMARY                 	This knowledge will significantly enhance our understanding of the
ST:STUDY_SUMMARY                 	pathophysiology of lower extremity symptoms in PAD, as well as the manner in
ST:STUDY_SUMMARY                 	which supervised exercise therapy improves walking intolerance. It will identify
ST:STUDY_SUMMARY                 	novel therapeutic targets and pathways for pharmacologic manipulation in the
ST:STUDY_SUMMARY                 	treatment of PAD. Aside from having the potential to generate multiple
ST:STUDY_SUMMARY                 	high-impact publications, it will serve as the basis for a planned NIH R01
ST:STUDY_SUMMARY                 	submission by the PI at the conclusion of the award period.
ST:INSTITUTE                     	USDA
ST:DEPARTMENT                    	Obesity and metabolism research unit
ST:LAST_NAME                     	Newman
ST:FIRST_NAME                    	John
ST:ADDRESS                       	430 West Health Sciences Dr. Davis, Ca, 95616
ST:EMAIL                         	john.newman@ars.usda.gov
ST:PHONE                         	(530) 752-1009
ST:STUDY_COMMENTS                	Fatty acids measured but not against a calibration curve. Therefore values are
ST:STUDY_COMMENTS                	expressed as a relative abundance of the entire samples set such that the sum of
ST:STUDY_COMMENTS                	all subjects eguals 100%.
#SUBJECT
SU:SUBJECT_TYPE                  	Human
SU:SUBJECT_SPECIES               	Homo sapiens
SU:TAXONOMY_ID                   	9606
SU:GENDER                        	Male
SU:SUBJECT_COMMENTS              	Individuals with peripheral arterial disease, as defined by ankle brachial
SU:SUBJECT_COMMENTS              	indices ≥0.4 and ≤0.8 and the presence of classic claudication symptoms
#SUBJECT_SAMPLE_FACTORS:         	SUBJECT(optional)[tab]SAMPLE[tab]FACTORS(NAME:VALUE pairs separated by |)[tab]Additional sample data
SUBJECT_SAMPLE_FACTORS           	-	P1 A01	Visit:v2 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P1 B01	Visit:v2 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P1 C01	Visit:v2 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P1 D01	Visit:v3 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P1 E01	Visit:v3 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P1 F01	Visit:v3 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P1 G01	Visit:v2 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P1 H01	Visit:v2 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P1 A02	Visit:v2 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P1 B02	Visit:v3 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P1 C02	Visit:v2 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P1 D02	Visit:v3 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P1 E02	Visit:v2 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P1 F02	Visit:v2 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P1 G02	Visit:v2 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P1 H02	Visit:v2 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P1 A03	Visit:v2 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P1 B03	Visit:v3 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P1 C03	Visit:v2 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P1 D03	Visit:v3 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P1 H03	Visit:v3 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P1 A04	Visit:v2 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P1 B04	Visit:v3 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P1 C04	Visit:v3 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P1 D04	Visit:v3 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P1 E04	Visit:v3 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P1 F04	Visit:v2 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P1 G04	Visit:v3 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P1 H04	Visit:v2 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P1 A05	Visit:v3 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P1 B05	Visit:v2 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P1 C05	Visit:v3 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P1 D05	Visit:v2 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P1 E05	Visit:v3 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P1 F05	Visit:v2 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P1 G05	Visit:v3 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P1 H05	Visit:v2 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P1 A06	Visit:v2 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P1 B06	Visit:v2 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P1 C06	Visit:v2 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P1 G06	Visit:v3 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P1 H06	Visit:v2 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P1 A07	Visit:v2 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P1 B07	Visit:v3 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P1 C07	Visit:v3 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P1 D07	Visit:v2 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P1 E07	Visit:v3 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P1 F07	Visit:v2 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P1 G07	Visit:v3 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P1 H07	Visit:v2 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P1 A08	Visit:v3 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P1 B08	Visit:v3 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P1 C08	Visit:v3 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P1 D08	Visit:v2 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P1 E08	Visit:v3 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P1 F08	Visit:v2 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P1 G08	Visit:v2 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P1 H08	Visit:v3 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P1 A09	Visit:v3 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P1 B09	Visit:v2 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P1 F09	Visit:v2 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P1 G09	Visit:v2 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P1 H09	Visit:v2 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P1 A10	Visit:v3 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P1 B10	Visit:v3 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P1 C10	Visit:v3 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P1 D10	Visit:v3 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P1 E10	Visit:v3 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P1 F10	Visit:v2 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P1 G10	Visit:v2 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P1 H10	Visit:v2 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P1 A11	Visit:v2 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P1 B11	Visit:v3 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P1 C11	Visit:v2 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P1 D11	Visit:v3 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P1 E11	Visit:v2 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P1 F11	Visit:v3 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P1 G11	Visit:v3 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P1 H11	Visit:v3 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P1 A12	Visit:v2 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P1 E12	Visit:v2 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P1 F12	Visit:v3 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P1 G12	Visit:v2 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P1 H12	Visit:v2 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P2 A01	Visit:v2 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P2 B01	Visit:v3 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P2 C01	Visit:v2 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P2 D01	Visit:v3 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P2 E01	Visit:v2 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P2 F01	Visit:v2 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P2 G01	Visit:v2 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P2 H01	Visit:v3 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P2 A02	Visit:v3 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P2 B02	Visit:v2 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P2 C02	Visit:v3 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P2 D02	Visit:v3 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P2 E02	Visit:v3 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P2 F02	Visit:v3 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P2 G02	Visit:v2 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P2 H02	Visit:v2 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P2 D03	Visit:v3 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P2 E03	Visit:v3 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P2 F03	Visit:v2 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P2 G03	Visit:v2 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P2 H03	Visit:v3 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P2 A04	Visit:v2 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P2 B04	Visit:v3 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P2 C04	Visit:v2 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P2 D04	Visit:v2 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P2 E04	Visit:v3 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P2 F04	Visit:v2 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P2 G04	Visit:v3 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P2 A05	Visit:v2 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P2 B05	Visit:v2 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P2 C05	Visit:v3 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P2 D05	Visit:v3 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P2 E05	Visit:v2 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P2 F05	Visit:v2 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P2 G05	Visit:v3 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P2 C06	Visit:v3 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P2 D06	Visit:v3 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P2 E06	Visit:v2 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P2 F06	Visit:v3 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P2 G06	Visit:v2 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P2 H06	Visit:v3 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P2 A07	Visit:v3 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P2 B07	Visit:v3 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P2 C07	Visit:v2 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P2 D07	Visit:v2 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P2 E07	Visit:v2 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P2 F07	Visit:v2 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P2 G07	Visit:v2 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P2 H07	Visit:v3 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P2 A08	Visit:v2 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P2 B08	Visit:v3 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P2 C08	Visit:v2 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P2 D08	Visit:v3 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P2 E08	Visit:v3 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P2 F08	Visit:v2 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P2 B09	Visit:v3 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P2 C09	Visit:v2 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P2 D09	Visit:v2 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P2 E09	Visit:v3 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P2 F09	Visit:v3 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P2 G09	Visit:v3 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P2 H09	Visit:v2 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P2 A10	Visit:v3 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P2 B10	Visit:v2 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P2 C10	Visit:v3 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P2 D10	Visit:v2 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P2 E10	Visit:v3 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P2 F10	Visit:v3 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P2 G10	Visit:v3 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P2 H10	Visit:v2 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P2 A11	Visit:v3 | Blood Draw:A	
SUBJECT_SAMPLE_FACTORS           	-	P2 B11	Visit:v3 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P2 C11	Visit:v3 | Blood Draw:B	
SUBJECT_SAMPLE_FACTORS           	-	P2 D11	Visit:v2 | Blood Draw:A	
#COLLECTION
CO:COLLECTION_SUMMARY            	Blood was drawn form the subject at the baseline (Visit 2 (V2)) before (B) and
CO:COLLECTION_SUMMARY            	after (A) the treadmill exercise test. Further, blood was collected after 12
CO:COLLECTION_SUMMARY            	weeks of supervised walking therapy (Visit 3 (V3)), before (B) and after (A) the
CO:COLLECTION_SUMMARY            	treadmill exercise test.
CO:SAMPLE_TYPE                   	Plasma
#TREATMENT
TR:TREATMENT_SUMMARY             	Subjects with peripheral arterial disease, as defined by ankle brachial indices
TR:TREATMENT_SUMMARY             	≥0.4 and ≤0.8 and the presence of classic claudication symptom were
TR:TREATMENT_SUMMARY             	subjected to the treadmill exercise test. Further, they underwent 12 weeks of
TR:TREATMENT_SUMMARY             	supervised walking therapy and subjected to the treadmill exercise test again.
#SAMPLEPREP
SP:SAMPLEPREP_SUMMARY            	Lipid mediator extraction and quantification: Oxylipins, endocannabinoids, and
SP:SAMPLEPREP_SUMMARY            	fatty acids were isolated from plasma using Ostro Sample Preparation Plates
SP:SAMPLEPREP_SUMMARY            	(Waters; Milford, MA) in the presence of BHT/EDTA and quantified by UPLC-MS/MS
SP:SAMPLEPREP_SUMMARY            	using internal standard methods. Briefly, in the Ostro Plate well, 100µl plasma
SP:SAMPLEPREP_SUMMARY            	aliquots were mixed with 5µl of BHT/EDTA (1:1 v/v MeOH/water) and 5µl methanol
SP:SAMPLEPREP_SUMMARY            	containing a suite of deuterated surrogates. The samples were then mixed with
SP:SAMPLEPREP_SUMMARY            	300µL of acetonitrile with 1% formic acid and eluted with 15 mmHg vacuum for 10
SP:SAMPLEPREP_SUMMARY            	min into 200µL glass inserts containing 10µl of 20% glycerol in methanol.
SP:SAMPLEPREP_SUMMARY            	Solvent was removed by vacuum centrifugation and the glycerol plug was stored at
SP:SAMPLEPREP_SUMMARY            	-80Co until analysis. Prior acquisition, samples were reconstituted in 100µl of
SP:SAMPLEPREP_SUMMARY            	1:1 methanol:acetonitrile containing 100nM of 1-cyclohexyl ureido, 3-dodecanoic
SP:SAMPLEPREP_SUMMARY            	acid (CUDA) and 1-phenyl ureido, 3-hexadecanoic acid (PUHA). Residues within
SP:SAMPLEPREP_SUMMARY            	extracts were separated on a 2.1 x 150mm 0.17µm BEH column (Waters) and
SP:SAMPLEPREP_SUMMARY            	detected by electrospray ionization with multi reaction monitoring on a API 6500
SP:SAMPLEPREP_SUMMARY            	QTRAP (Sciex; Redwood City, CA) and quantified against 7-9 point calibration
SP:SAMPLEPREP_SUMMARY            	curves of authentic standards using modifications of previously reported methods
SP:SAMPLEPREP_SUMMARY            	(Grapov, D., et al. 2012. PLoS One 7: e48852.; doi:
SP:SAMPLEPREP_SUMMARY            	10.1371/journal.pone.0048852).
#CHROMATOGRAPHY
CH:CHROMATOGRAPHY_TYPE           	Reversed phase
CH:INSTRUMENT_NAME               	Waters Acquity
CH:COLUMN_NAME                   	Waters Acquity BEH C18 (100 x 2mm, 1.7um)
CH:FLOW_GRADIENT                 	See protocol/methods file
CH:FLOW_RATE                     	0.25 uL
CH:COLUMN_TEMPERATURE            	60 °C
CH:METHODS_FILENAME              	2017_6500_OxyEndo_Analysis_protocol.pdf
CH:SOLVENT_A                     	0.1% acetic acid
CH:SOLVENT_B                     	90% ACN / 10% IPA
CH:INTERNAL_STANDARD             	See protocol/methods file
CH:RETENTION_TIME                	See protocol/methods file
CH:SAMPLE_INJECTION              	5 µL
CH:ANALYTICAL_TIME               	20 min
CH:WEAK_WASH_SOLVENT_NAME        	20% methanol, 10% isopropanol
CH:WEAK_WASH_VOLUME              	600 µL
CH:STRONG_WASH_SOLVENT_NAME      	50:50 Acetonitrile:Methanol
CH:STRONG_WASH_VOLUME            	600 µL
#ANALYSIS
AN:ANALYSIS_TYPE                 	MS
AN:LABORATORY_NAME               	Newman
AN:OPERATOR_NAME                 	Kamil Borkowski
AN:SOFTWARE_VERSION              	AB Sciex MultiQuant version 3.0.1
#MS
MS:INSTRUMENT_NAME               	ABI Sciex 6500 QTrap
MS:INSTRUMENT_TYPE               	Triple quadrupole
MS:MS_TYPE                       	ESI
MS:ION_MODE                      	NEGATIVE
MS:MS_COMMENTS                   	Oxylipin Analysis
#MS_METABOLITE_DATA
MS_METABOLITE_DATA:UNITS         	Concentration pmol/g
MS_METABOLITE_DATA_START
Samples	P1 A01	P1 B01	P1 C01	P1 D01	P1 E01	P1 F01	P1 G01	P1 H01	P1 A02	P1 B02	P1 C02	P1 D02	P1 E02	P1 F02	P1 G02	P1 H02	P1 A03	P1 B03	P1 C03	P1 D03	P1 H03	P1 A04	P1 B04	P1 C04	P1 D04	P1 E04	P1 F04	P1 G04	P1 H04	P1 A05	P1 B05	P1 C05	P1 D05	P1 E05	P1 F05	P1 G05	P1 H05	P1 A06	P1 B06	P1 C06	P1 G06	P1 H06	P1 A07	P1 B07	P1 C07	P1 D07	P1 E07	P1 F07	P1 G07	P1 H07	P1 A08	P1 B08	P1 C08	P1 D08	P1 E08	P1 F08	P1 G08	P1 H08	P1 A09	P1 B09	P1 F09	P1 G09	P1 H09	P1 A10	P1 B10	P1 C10	P1 D10	P1 E10	P1 F10	P1 G10	P1 H10	P1 A11	P1 B11	P1 C11	P1 D11	P1 E11	P1 F11	P1 G11	P1 H11	P1 A12	P1 E12	P1 F12	P1 G12	P1 H12	P2 A01	P2 B01	P2 C01	P2 D01	P2 E01	P2 F01	P2 G01	P2 H01	P2 A02	P2 B02	P2 C02	P2 D02	P2 E02	P2 F02	P2 G02	P2 H02	P2 D03	P2 E03	P2 F03	P2 G03	P2 H03	P2 A04	P2 B04	P2 C04	P2 D04	P2 E04	P2 F04	P2 G04	P2 A05	P2 B05	P2 C05	P2 D05	P2 E05	P2 F05	P2 G05	P2 C06	P2 D06	P2 E06	P2 F06	P2 G06	P2 H06	P2 A07	P2 B07	P2 C07	P2 D07	P2 E07	P2 F07	P2 G07	P2 H07	P2 A08	P2 B08	P2 C08	P2 D08	P2 E08
Factors	Visit:v2 | Blood Draw:A	Visit:v2 | Blood Draw:B	Visit:v2 | Blood Draw:A	Visit:v3 | Blood Draw:B	Visit:v3 | Blood Draw:A	Visit:v3 | Blood Draw:B	Visit:v2 | Blood Draw:B	Visit:v2 | Blood Draw:A	Visit:v2 | Blood Draw:B	Visit:v3 | Blood Draw:A	Visit:v2 | Blood Draw:A	Visit:v3 | Blood Draw:A	Visit:v2 | Blood Draw:B	Visit:v2 | Blood Draw:A	Visit:v2 | Blood Draw:B	Visit:v2 | Blood Draw:A	Visit:v2 | Blood Draw:A	Visit:v3 | Blood Draw:A	Visit:v2 | Blood Draw:B	Visit:v3 | Blood Draw:B	Visit:v3 | Blood Draw:A	Visit:v2 | Blood Draw:B	Visit:v3 | Blood Draw:B	Visit:v3 | Blood Draw:B	Visit:v3 | Blood Draw:B	Visit:v3 | Blood Draw:B	Visit:v2 | Blood Draw:B	Visit:v3 | Blood Draw:A	Visit:v2 | Blood Draw:A	Visit:v3 | Blood Draw:A	Visit:v2 | Blood Draw:B	Visit:v3 | Blood Draw:A	Visit:v2 | Blood Draw:A	Visit:v3 | Blood Draw:B	Visit:v2 | Blood Draw:A	Visit:v3 | Blood Draw:B	Visit:v2 | Blood Draw:B	Visit:v2 | Blood Draw:A	Visit:v2 | Blood Draw:B	Visit:v2 | Blood Draw:A	Visit:v3 | Blood Draw:A	Visit:v2 | Blood Draw:A	Visit:v2 | Blood Draw:A	Visit:v3 | Blood Draw:B	Visit:v3 | Blood Draw:B	Visit:v2 | Blood Draw:A	Visit:v3 | Blood Draw:A	Visit:v2 | Blood Draw:A	Visit:v3 | Blood Draw:A	Visit:v2 | Blood Draw:A	Visit:v3 | Blood Draw:A	Visit:v3 | Blood Draw:A	Visit:v3 | Blood Draw:A	Visit:v2 | Blood Draw:A	Visit:v3 | Blood Draw:A	Visit:v2 | Blood Draw:B	Visit:v2 | Blood Draw:B	Visit:v3 | Blood Draw:B	Visit:v3 | Blood Draw:A	Visit:v2 | Blood Draw:B	Visit:v2 | Blood Draw:B	Visit:v2 | Blood Draw:B	Visit:v2 | Blood Draw:A	Visit:v3 | Blood Draw:A	Visit:v3 | Blood Draw:B	Visit:v3 | Blood Draw:A	Visit:v3 | Blood Draw:B	Visit:v3 | Blood Draw:A	Visit:v2 | Blood Draw:B	Visit:v2 | Blood Draw:A	Visit:v2 | Blood Draw:B	Visit:v2 | Blood Draw:B	Visit:v3 | Blood Draw:B	Visit:v2 | Blood Draw:B	Visit:v3 | Blood Draw:B	Visit:v2 | Blood Draw:A	Visit:v3 | Blood Draw:B	Visit:v3 | Blood Draw:B	Visit:v3 | Blood Draw:A	Visit:v2 | Blood Draw:A	Visit:v2 | Blood Draw:A	Visit:v3 | Blood Draw:A	Visit:v2 | Blood Draw:B	Visit:v2 | Blood Draw:B	Visit:v2 | Blood Draw:B	Visit:v3 | Blood Draw:B	Visit:v2 | Blood Draw:A	Visit:v3 | Blood Draw:B	Visit:v2 | Blood Draw:A	Visit:v2 | Blood Draw:A	Visit:v2 | Blood Draw:A	Visit:v3 | Blood Draw:B	Visit:v3 | Blood Draw:B	Visit:v2 | Blood Draw:B	Visit:v3 | Blood Draw:B	Visit:v3 | Blood Draw:A	Visit:v3 | Blood Draw:B	Visit:v3 | Blood Draw:B	Visit:v2 | Blood Draw:A	Visit:v2 | Blood Draw:A	Visit:v3 | Blood Draw:B	Visit:v3 | Blood Draw:B	Visit:v2 | Blood Draw:A	Visit:v2 | Blood Draw:A	Visit:v3 | Blood Draw:B	Visit:v2 | Blood Draw:B	Visit:v3 | Blood Draw:A	Visit:v2 | Blood Draw:A	Visit:v2 | Blood Draw:B	Visit:v3 | Blood Draw:B	Visit:v2 | Blood Draw:A	Visit:v3 | Blood Draw:B	Visit:v2 | Blood Draw:A	Visit:v2 | Blood Draw:A	Visit:v3 | Blood Draw:B	Visit:v3 | Blood Draw:B	Visit:v2 | Blood Draw:B	Visit:v2 | Blood Draw:B	Visit:v3 | Blood Draw:A	Visit:v3 | Blood Draw:A	Visit:v3 | Blood Draw:B	Visit:v2 | Blood Draw:B	Visit:v3 | Blood Draw:A	Visit:v2 | Blood Draw:A	Visit:v3 | Blood Draw:A	Visit:v3 | Blood Draw:B	Visit:v3 | Blood Draw:A	Visit:v2 | Blood Draw:B	Visit:v2 | Blood Draw:B	Visit:v2 | Blood Draw:B	Visit:v2 | Blood Draw:B	Visit:v2 | Blood Draw:B	Visit:v3 | Blood Draw:A	Visit:v2 | Blood Draw:B	Visit:v3 | Blood Draw:B	Visit:v2 | Blood Draw:A	Visit:v3 | Blood Draw:B	Visit:v3 | Blood Draw:A
6-keto PGF1a	0.456	0.26	0.348	0.378	0.304	0.209	0.3	0.344	0.416	0.275	0.374	0.341	0.241	0.327	0.157	0.264	0.323	0.26	0.393	0.299	0.21	0.191	0.202	0.164	0.162	0.216	0.295	0.196	0.329	0.141	0.284	0.204	0.471	0.241	0.274	0.169	0.331	0.383	0.239	0.175	0.667	0.222	0.258	0.285	0.268	0.234	0.268	0.205	0.239	0.585	0.202	0.18	0.231	0.257	0.171	0.233	0.396	0.357	0.523	0.42	0.406	0.253	0.449	0.344	0.183	0.498	0.0884	0.362	0.187	0.269	0.253	0.419	0.243	0.163	0.289	0.158	0.199	0.244	0.263	0.189	0.228	0.255	0.181	0.694	0.383	0.383	0.443	0.301	0.196	0.33	0.161	0.207	0.238	0.408	0.267	0.211	0.339	0.643	0.254	0.339	0.549	0.192	0.295	0.241	0.579	0.105	0.375	0.334	0.309	0.587	0.222	0.305	0.309	0.257	0.251	0.186	0.582	0.239	0.254	0.32	0.402	0.34	0.261	0.205	0.256	0.25	0.422	0.327	0.392	0.242	0.432	0.435	0.284	0.31	0.278	0.734	0.176	0.326
PGF2a	1.31	0.258	0.548	0.635	0.0522	0.333	0.382	0.615	0.397	0.607	1.19	0.476	0.573	0.162	0.485	0.189	0.169	0.144	0.173	0.1	0.338	0.181	0.423	0.211	0.108	0.0464	0.47	0.174	0.208	0.126	0.667	0.935	1.08	0.109	0.89	0.044	1.39	2.32	0.642	0.137	3.01	0.0842	1.17	2.14	0.411	0.35	1.71	0.172	0.49	3.74	0.0873	0.0683	0.391	2.3	1.83	0.329	2.66	1.53	2.67	0.921	0.274	0.734	1.35	1.53	0.65	3.26	0.149	2.14	0.205	0.4	ND	1.51	1.2	0.0846	0.355	0.0188	0.046	0.123	0.214	0.113	0.824	0.503	0.0613	0.179	1.91	0.0747	1.89	0.119	0.255	0.472	0.561	0.214	0.238	0.827	0.406	0.219	0.78	3.59	0.19	0.633	0.955	0.0857	0.0555	0.161	1.77	0.278	0.933	0.652	0.184	1.88	0.111	0.349	0.191	0.825	0.1	0.536	0.867	0.454	0.183	1.24	2.02	0.692	0.531	0.072	0.291	0.586	3.3	0.273	2.06	0.555	3	3.77	0.604	0.475	1.25	3.29	0.512	0.055
15-deoxy PGJ2	0.14	0.0487	0.0492	0.0552	0.0461	0.0383	0.0513	0.0194	0.11	0.0427	0.0762	0.0496	0.0654	0.0623	0.0338	0.0333	0.0745	0.035	0.0109	0.0556	0.0357	0.0681	0.0507	0.0827	0.0431	0.0408	0.0527	0.0789	0.116	0.0908	0.115	0.0441	0.0202	0.0718	0.11	0.0626	0.087	0.0775	0.0635	0.0875	0.0765	0.0518	0.127	0.0976	0.0988	0.0903	0.0939	0.0891	0.0773	0.0686	0.1	0.076	0.0851	0.0807	0.0709	0.106	0.0754	0.085	0.0618	0.132	0.0788	0.077	0.099	0.101	0.12	0.0881	0.0638	0.104	0.0581	0.0609	0.113	0.0933	0.116	0.11	0.0996	0.0921	0.0699	0.0711	0.0978	0.144	0.0947	0.0613	0.0805	0.184	0.171	0.123	0.097	0.0825	0.109	0.0663	0.0548	0.0912	0.114	0.0905	0.0673	0.0817	0.0759	0.0844	0.0852	0.0944	0.104	0.0495	0.0956	0.0852	0.0769	0.123	0.0986	0.0839	0.102	0.101	0.0949	0.0883	0.0775	0.102	0.0773	0.106	0.0927	0.0628	0.196	0.14	0.174	0.0898	0.121	0.0989	0.0921	0.156	0.203	0.119	0.114	0.15	0.106	0.129	0.0935	0.203	0.134	0.122	0.114	0.19
PGF2a EA	0.0394	0.00352	ND	ND	0.00232	0.0613	ND	ND	0.0738	0.0000877	0.0832	0.0636	ND	ND	0.0279	0.0223	0.0461	ND	ND	ND	ND	0.0248	ND	ND	ND	ND	0.00258	ND	0.146	ND	ND	ND	0.000147	0.0509	0.147	0.00694	0.182	ND	0.0831	ND	0.00536	0.0497	0.00281	ND	0.0259	0.0404	ND	ND	0.0395	0.00672	ND	ND	0.0297	ND	ND	ND	0.0344	ND	ND	ND	ND	0.0439	0.0924	0.00872	ND	ND	ND	0.00648	ND	ND	ND	ND	ND	0.0636	0.0474	0.13	ND	0.208	ND	ND	ND	ND	0.013	ND	ND	0.207	ND	ND	0.0568	ND	0.0327	ND	0.0711	ND	ND	0.027	0.0379	0.0357	0.121	0.0378	ND	ND	0.0101	ND	0.291	0.0336	ND	0.0286	0.115	ND	ND	0.00824	0.0891	0.209	ND	0.0605	0.00199	0.055	0.0205	ND	0.0618	ND	0.134	ND	0.105	0.054	0.149	ND	0.0502	ND	ND	0.0751	ND	0.0379	0.0576	0.142	0.0822	0.0814
11-HETE	3.21	1.58	1.12	6.29	2.26	1.56	2.11	3.94	1.34	2.56	1.03	0.792	0.803	1.16	1.23	1.2	0.643	1.24	0.776	1.54	1.15	0.834	0.387	0.556	0.794	0.587	1.02	0.709	0.979	0.809	0.576	4.78	8.62	1.34	0.749	0.773	0.633	1.07	0.801	0.856	1.05	0.71	1.76	0.4	1.39	1.43	0.549	0.487	0.968	0.411	4.91	0.568	0.801	0.46	0.517	0.471	0.689	0.768	0.898	1.07	0.572	0.827	4.19	0.575	0.676	1.1	0.614	0.521	1.95	0.606	1.28	1.95	0.952	0.331	0.69	0.65	0.447	1.38	0.979	1.16	3.08	1.17	0.618	0.601	1.52	2.05	0.993	0.347	2.77	1.19	0.727	0.565	0.79	0.929	0.502	0.749	0.697	0.484	0.477	3.08	1.12	0.479	1.06	1.27	1.09	0.544	0.894	0.954	1.7	0.551	1.01	0.622	0.696	0.76	0.633	0.485	0.876	0.438	0.613	1.15	0.673	0.395	0.519	0.512	0.71	0.632	0.888	0.552	1.63	0.615	0.809	0.415	1.61	0.98	0.515	1.05	0.553	1.04
9_12_13-TriHOME	3.78	1.88	1.94	2.4	1.65	0.82	1.81	2.18	1.85	2.02	3.27	1.76	1.46	2.04	1.99	1.54	1.17	1.12	2.8	1.51	1.66	3.07	5.47	1.27	0.806	1.01	1.15	1.12	1.73	1.31	1.11	1.61	2.44	1.24	1.37	1.24	0.768	1.29	0.798	1.68	1.31	3.32	1.23	2	0.947	2.06	1.49	1.64	1.37	2.01	1.97	1.54	1.28	2.43	1.49	1.65	1.15	1.15	1.3	2.21	1.26	2.36	2.38	1.92	1.36	1.9	0.682	4.22	1.83	1.43	5.85	1.25	6.1	2.55	0.969	0.869	1.93	1.19	1.25	1.62	1.23	1.12	1.09	2.81	3.2	5.85	1.12	2.61	2.27	1.63	1.84	1.32	1.81	1.2	3.55	4.35	1.63	2.08	0.819	2.74	1.07	2.37	5.35	0.922	1.63	2.25	1.72	1.13	1.73	4.01	1.38	1.55	1.03	1.27	1.11	1.34	1.65	1.67	3.05	1.78	4.16	1.15	1.89	1.29	1.88	1.31	8.79	2.75	1.27	2.01	3.42	1.93	1.59	1.98	1.06	1.92	1.58	5.98
9_10-e-DiHO	9.38	5.02	7.92	5.2	6.03	3.53	5.65	7.51	9.64	4.62	7.92	10	6.93	5.1	8.52	7.79	8.83	3.84	16.4	9.56	10.5	11	12.8	4.57	5.31	6.56	10.4	6.47	8.1	16.4	8.79	4.65	8.54	5.18	11.7	5.84	6.15	4.64	3.49	7.5	6.23	13.2	4.65	10.4	6.61	6.88	7.96	5.11	8.46	7	4.91	5.84	9.94	9.22	6.21	6.71	6.03	8.1	4.68	15.7	9.42	10.9	13.3	9.92	6.91	9.29	8.97	10.5	6.77	7.39	16.8	4.63	20.4	14.2	8.12	7.6	6.06	5.05	7.17	7.35	4.45	10.8	9.2	29.3	10.5	4.99	3.87	6.37	6.06	7.67	10.7	5.65	6.47	5.89	10.3	19	7.18	6.31	3.49	5.86	3.9	11.9	11.7	5.36	5.32	7.9	6.42	5.59	4.82	13.4	8.28	7.41	6.5	4.95	8.34	3.36	6.95	4.24	17	10.6	18.5	7.57	7.84	7.06	9.86	5.64	23.5	8.61	5.6	8.86	6.06	6.97	9.58	7.63	6.28	4.66	7.7	8.28
12_13-DiHOME	2.79	4.39	3.9	1.59	1.98	1.49	1.57	2.25	3.98	1.39	4.05	9.84	3.72	1.77	4.94	7.81	2.03	2.27	4.72	4.84	10.1	2.56	8.44	2.22	2.19	2.07	5.65	3.25	2.39	4.64	3.92	1.31	1.58	2.58	6.77	2.63	1.54	1.57	1.14	4.96	1.14	2.43	1.44	2.66	1.91	1.63	4.3	4.18	4.48	5	2.92	2.52	4.95	4.35	4.47	2.42	1.83	2.03	1.9	7.08	1.43	3.38	8.94	3.3	3.63	4.25	2.48	3.82	2.57	2.24	10.4	1.24	13.1	2.66	2.88	2.76	2	2.92	3.96	2.99	1.62	5.11	2.87	4.5	4.52	3.73	1.44	2.02	1.61	5.3	3.23	3.43	1.74	1.39	2.36	23.6	4.28	3.81	1.32	3.7	1.69	5.48	10.1	3.64	1.38	2.8	2.28	2.38	1.51	2.81	2.32	4.89	3.93	2.86	3.37	1.06	3.08	1.59	6.35	2.89	3.63	2.8	4.46	3.7	2.38	2.61	16.4	7.84	1.49	3.61	2.61	6.65	2.38	2.95	3.12	2.17	1.97	8.54
9_10-DiHOME	5.5	4.59	3.45	2.39	3.07	1.57	2.11	3.64	5.58	2.32	4.36	8.02	4.27	2.34	8.85	7.29	3.22	1.9	10.6	6.26	13.4	2.69	13.5	3.3	2.55	2.64	8.37	4.01	3.79	4.14	5.67	1.6	3.33	3.39	8.82	3.46	2.86	2.4	1.77	7.47	3.04	3.92	2.2	4.55	3.25	2.21	5.52	5.75	6.18	4.62	3.84	3.12	7.23	5.08	6.51	4.7	2.43	3.29	3.04	12.4	3.5	4.68	10.5	5.24	7.41	5.03	2.47	4.35	3.02	3.71	16.2	1.51	28.7	3.96	4.97	3.07	2.75	2.67	5.95	3.28	1.86	5.74	3.44	14	7.86	6.36	1.86	3.6	2.59	9.39	5.69	5.69	2.59	3.21	3.71	33.2	8.97	5.04	2.14	4.86	2.78	7.39	17.1	4.31	2.36	4.65	3.7	3.52	2.2	4.65	3.67	5.31	5.49	2.73	4.61	1.8	4.25	2.18	8.36	4.98	7	3	6.21	4.35	4.12	3.61	32.5	10.7	2.55	4.57	4.15	4.58	4.36	3.93	3.93	2.73	2.98	11.8
15_16-DiHODE	8.36	8.88	9.38	2.5	5.6	3.3	5.11	4.27	12.7	4.12	9.48	23	16.8	6.44	15.6	15	8.4	5.87	52.6	14.7	23.7	11.2	99.4	4.2	5.98	4.76	14	12.1	10.1	13.7	8.46	4.05	2.79	8.75	16.3	10.3	2.79	3	4.51	12.6	5.02	11.1	5.33	11	5.55	4.28	18.7	13.7	11.8	11.3	10.7	8.86	16.2	26.1	9.22	7.48	5.58	4.87	11.5	16.8	6.49	8.8	32.6	15.7	11.4	14.3	6.11	11.4	5.85	6.54	41.7	3.33	41.6	8.72	6.41	8.52	5.03	7.32	10.6	6.62	6.26	12.4	10.2	9.79	12.1	13.1	3.9	4.9	4.36	16.8	5.67	5.06	4.12	4.11	5.18	42.9	15.3	10	3.77	7.17	9.03	9.09	37	6.68	4.8	5.31	4.16	4.68	3.76	6.22	6.01	12.3	8.65	6.42	6.67	2.74	7.21	3.06	14.2	6.99	30.2	6.84	8.17	7.5	6.26	7.74	46.3	21.8	2.26	7.03	4.61	10.5	6.72	10.5	8.27	7.33	5.01	27.4
12_13-DiHODE	0.323	0.269	0.249	0.0376	0.054	0.0385	0.078	0.012	0.33	0.0982	0.242	0.677	0.197	0.135	0.477	0.49	0.145	0.132	0.34	0.406	0.763	0.164	0.836	0.135	0.108	0.127	0.288	0.231	0.161	0.167	0.204	0.0557	0.0414	0.141	0.555	0.16	0.0738	0.0959	0.0486	0.345	0.0598	0.198	0.0874	0.233	0.128	0.0727	0.339	0.338	0.363	0.224	0.171	0.125	0.441	0.307	0.203	0.116	0.138	0.142	0.104	0.561	0.0793	0.22	0.8	0.326	0.268	0.485	0.0838	0.191	0.205	0.192	1.2	0.0707	1.52	0.199	0.118	0.158	0.111	0.18	0.148	0.184	0.0691	0.394	0.0753	0.228	0.436	0.295	0.0694	0.0828	0.0285	0.409	0.133	0.128	0.0703	0.0567	0.143	1.38	0.307	0.342	0.0802	0.207	0.131	0.282	0.932	0.194	0.0953	0.195	0.12	0.155	0.0868	0.149	0.162	0.368	0.24	0.182	0.214	0.0867	0.231	0.0473	0.352	0.226	0.388	0.221	0.263	0.281	0.142	0.163	2.27	0.537	0.0262	0.307	0.233	0.249	0.183	0.194	0.184	0.2	0.127	0.619
9_10-DiHODE	0.703	0.349	0.306	0.161	0.271	0.0971	0.205	0.485	0.763	0.282	0.518	0.865	0.277	0.244	1.13	0.55	0.628	0.102	2.17	0.675	1.41	0.164	2.89	0.268	0.155	0.225	1.05	0.332	0.579	0.278	0.54	0.12	0.169	0.276	0.88	0.281	0.392	0.227	0.235	0.374	0.658	0.449	0.223	0.685	0.24	0.19	0.322	0.513	0.5	0.424	0.441	0.204	0.904	0.471	0.323	0.677	0.25	0.229	0.419	1.6	0.795	0.351	1.28	0.702	0.886	0.616	0.0852	0.274	0.226	0.559	2.07	0.133	4.36	0.393	0.487	0.271	0.19	0.269	0.556	0.343	0.257	0.668	0.376	2.1	0.784	0.538	0.187	0.413	0.195	0.999	0.207	0.245	0.166	0.384	0.144	2.46	0.914	0.452	0.143	0.231	0.249	0.418	2.02	0.183	0.196	0.165	0.368	0.276	0.0888	0.433	0.5	0.41	0.582	0.15	0.395	0.0712	0.354	0.0617	0.91	0.505	1.25	0.264	0.531	0.344	0.647	0.21	5.05	1.15	0.112	0.304	0.28	0.4	0.455	0.432	0.24	0.461	0.319	1.2
14_15-DiHETrE	1.08	1.11	0.81	0.889	0.594	1.11	0.674	0.807	0.696	1.08	0.861	0.971	0.606	0.703	1.33	1.37	0.548	0.829	0.463	1.47	1.26	0.614	0.41	0.37	1.09	0.449	1.29	1.22	0.929	1.03	0.807	1.07	1.24	0.978	1.01	0.996	0.96	1.3	1.08	0.798	0.561	0.625	0.679	0.547	0.674	0.744	0.71	0.63	1.24	0.551	1.12	0.75	1.57	0.586	0.583	0.748	0.878	1.22	0.717	1.13	0.564	0.88	1.07	0.61	0.975	0.681	0.708	0.564	0.674	0.552	0.898	0.436	1.09	0.725	1.24	0.629	0.683	0.865	1.52	0.545	1.04	0.612	0.68	0.629	1.33	0.682	0.462	0.647	1.06	1.2	0.433	0.544	0.822	0.659	0.765	1.19	1.01	0.648	0.854	0.79	0.921	0.695	0.863	2.08	0.544	0.381	0.843	1.43	0.96	0.491	0.746	0.901	1.04	0.817	0.507	0.994	0.694	0.771	1.03	1.06	0.706	0.875	0.461	0.995	1.27	0.794	1.35	0.687	1.15	0.632	1.64	0.543	0.595	1.16	0.635	0.778	1.17	0.838
11_12-DiHETrE	0.905	0.856	0.735	0.826	0.63	0.831	0.631	0.793	0.621	1.03	0.686	0.797	0.544	0.555	1.31	0.976	0.517	0.635	0.363	1.14	0.977	0.621	0.39	0.411	0.893	0.423	1.1	0.955	0.754	0.658	0.736	0.785	1.33	0.823	0.958	0.798	0.97	1.1	0.728	0.771	0.514	0.657	0.613	0.497	0.757	0.548	0.623	0.577	1	0.492	0.963	0.6	1.11	0.491	0.51	0.733	0.695	1.11	0.571	1.05	0.438	0.876	0.862	0.544	0.842	0.543	0.436	0.538	0.687	0.355	0.738	0.422	0.861	0.681	1.1	0.385	0.565	0.652	1.4	0.476	0.69	0.503	0.394	0.689	1.06	0.559	0.454	0.629	0.869	1.05	0.335	0.495	0.572	0.539	0.66	0.957	0.737	0.496	0.657	0.665	0.754	0.606	0.71	1.99	0.544	0.325	0.734	1.28	0.749	0.427	0.557	0.793	0.823	0.701	0.424	0.952	0.582	0.731	0.948	0.799	0.59	0.747	0.484	1.11	1.08	0.658	1.05	0.616	1.2	0.547	1.48	0.476	0.537	0.946	0.562	0.665	1.03	0.683
8_9-DiHETrE	0.33	0.295	0.283	0.439	0.364	0.54	0.312	0.287	0.236	0.425	0.305	0.326	0.228	0.272	0.583	0.3	0.191	0.321	0.184	0.349	0.569	0.199	0.203	0.202	0.293	0.163	0.335	0.456	0.336	0.387	0.389	0.51	0.637	0.347	0.43	0.307	0.42	0.456	0.521	0.279	0.242	0.232	0.366	0.24	0.399	0.276	0.257	0.228	0.309	0.268	0.338	0.263	0.36	0.203	0.177	0.551	0.426	0.53	0.307	0.561	0.198	0.366	0.332	0.291	0.397	0.202	0.337	0.261	0.191	0.199	0.272	0.209	0.314	0.259	0.927	0.291	0.201	0.302	1.05	0.158	0.546	0.219	0.298	0.262	0.451	0.23	0.16	0.203	0.325	0.415	0.186	0.175	0.257	0.245	0.276	0.438	0.407	0.191	0.207	0.337	0.403	0.224	0.255	0.539	0.168	0.225	0.268	0.586	0.259	0.242	0.188	0.254	0.196	0.418	0.197	0.377	0.25	0.227	0.369	0.27	0.443	0.31	0.228	0.347	0.464	0.367	0.366	0.269	0.617	0.235	0.707	0.291	0.315	0.475	0.218	0.379	0.433	0.31
5_6-DiHETrE	0.461	0.285	0.185	0.412	0.407	0.379	0.333	0.164	0.197	0.274	0.171	0.187	0.175	0.177	0.358	0.277	0.134	0.15	0.18	0.302	0.465	0.208	0.169	0.134	0.221	0.0975	0.283	0.451	0.18	0.326	0.544	0.398	0.546	0.258	0.389	0.352	0.413	0.311	0.459	0.18	0.104	0.222	0.322	0.214	0.387	0.101	0.202	0.234	0.281	0.193	0.273	0.192	0.359	0.176	0.143	0.599	0.578	0.37	0.282	0.517	0.13	0.251	0.239	0.208	0.323	0.107	0.243	0.184	0.243	0.171	0.227	0.0646	0.35	0.161	0.916	0.193	0.157	0.188	1.22	0.0597	0.426	0.166	0.311	0.179	0.501	0.341	0.124	0.261	0.146	0.325	0.093	0.144	0.168	0.248	0.249	0.268	0.385	0.12	0.173	0.48	0.238	0.191	0.214	0.367	0.0784	0.125	0.176	0.418	0.121	0.212	0.201	0.122	0.158	0.51	0.164	0.229	0.136	0.0952	0.39	0.223	0.557	0.199	0.142	0.377	0.401	0.339	0.51	0.369	0.618	0.15	0.488	0.239	0.344	0.213	0.135	0.342	0.462	0.295
14_15-DiHETE	0.801	0.443	0.533	0.919	0.476	0.709	0.491	0.641	0.538	0.807	0.48	0.634	0.628	0.427	0.735	0.649	0.259	0.39	0.184	0.601	0.671	0.268	0.336	0.223	0.364	0.343	0.485	0.584	0.26	0.516	0.335	0.699	1.07	0.468	0.947	0.498	0.71	1.5	0.573	0.405	0.681	0.282	0.442	0.811	0.576	0.251	0.548	0.497	0.466	1.05	0.487	0.284	0.583	0.8	0.78	0.208	1.08	0.999	0.636	1.05	0.308	0.544	0.936	1.05	0.461	3.42	0.323	0.985	0.26	0.247	0.4	0.601	0.471	0.208	0.572	0.353	0.267	0.391	0.561	0.196	0.749	0.282	0.525	0.411	0.638	0.399	0.632	0.297	0.543	0.751	0.135	0.14	0.245	0.304	0.406	0.881	0.745	2.7	0.226	0.393	0.77	0.322	0.554	0.799	0.585	0.235	0.522	1.24	0.401	0.783	0.331	0.493	0.482	0.964	0.331	0.493	0.433	0.636	0.28	0.661	1.12	0.628	0.17	0.418	0.796	0.128	0.71	0.537	1.05	0.3	2.24	1.31	0.408	0.624	0.158	1.18	0.918	0.634
19_20-DiHDoPA	1.66	1.05	1.14	2.15	0.649	2.29	1	1.39	0.868	2.92	1.51	1.17	2.73	1.35	2.31	1.21	1.01	0.869	0.991	1.6	2.32	0.843	0.911	0.188	1.87	0.596	2.43	2.8	1.1	1.3	1.74	2.19	3.96	1.76	3.17	2.2	2.03	4.09	2.22	0.509	1.63	0.767	1.02	1.51	0.66	0.943	3	1.86	2.07	2.46	1.82	1.12	1.5	1.11	2.54	1.26	2.76	3	2.44	3.32	0.971	2.37	1.17	1.7	1.67	2.96	0.975	2.41	0.803	1.02	1.64	1.05	1.66	0.887	1.79	0.744	1.04	0.9	2.38	0.68	2.45	1.14	0.765	0.442	2.04	1.23	1.05	0.762	1.43	2.06	0.158	0.324	1.04	1.38	1.07	2.18	1.98	2.9	1.59	1.54	2.93	1	1.61	2.57	1.46	0.222	1.37	3.01	1.16	2.13	0.899	1.23	1.88	2.54	1.03	2.43	1.1	1.32	1.32	1.35	2.13	1.07	0.192	1.11	1.74	1.11	2	1.89	3.6	0.932	5.11	2.32	1.05	1.27	1.17	2.52	1.53	1.73
13-HODE	68.1	34.3	29.5	91.7	40.6	17.1	33	45.2	24.8	60.1	24.2	23.6	31.3	23.2	34.3	41	16.6	17.5	22.3	39.5	68	17.3	24.6	9.6	16.8	13.8	29.7	19.2	18.3	24.2	19.8	84.6	79.8	25.1	34.4	24.2	7.24	19.4	11	26.5	14.1	17.1	25.9	16.7	17.3	27.6	28.8	17.2	31.5	21.3	84.9	18.6	29.3	22.5	41.9	10.7	13.2	11.9	17.3	42.9	13.2	24.6	71	22	23.4	25.1	10.3	20.5	61.5	16.3	49.1	26.2	47.9	12	14.6	18.4	16.2	20.6	23.3	33.5	37.5	26.3	16.8	57.2	46.9	58.1	18	17.5	66	43.1	23.9	19.3	17.2	27.6	10.5	83.6	26	17.8	9	33.8	18.3	25.7	41.8	19	20.4	14	13.6	15.3	35.3	21.1	24.1	15.5	22.3	24.6	22.9	11.4	24.6	9.64	31.7	25.8	23.1	12.9	19.8	30.8	13	17.5	57.9	30.8	16.9	21	26.2	29.9	52.6	23.6	20.7	26.8	11.5	34.9
9-HODE	52.9	27.2	25	75.8	34.8	14.9	28.6	43.8	21.2	53.3	23.8	19.4	27.9	21.2	29	27.6	14.1	13.3	28.5	29.3	49	16	17.2	8.02	14.6	12	22.3	17.2	17.6	16.2	17.1	61	67.4	20.4	27	19.5	6.66	17	9.31	19.5	13.8	18	22.7	17.3	16.4	22.2	26.5	13.8	27.3	16.3	66.7	16.2	19.8	21	28.5	9.99	11.4	11.1	14.4	40.9	13.1	21.7	59	27.4	23.1	22.5	8.07	20.4	53.6	14.1	59.5	22.4	65.7	11.2	12.5	13.8	14.8	20.5	19.1	29.5	34.8	24.1	14.6	61.6	35.5	43.2	14.3	26.3	49.5	31.1	18.1	15.6	15.2	23.2	9.7	59.8	17.9	13.2	7.19	32.6	13.8	20	45.4	16.1	17.5	11.7	14.1	13.2	29.2	18.4	19.6	12.4	17	18.6	16.6	9.46	21.9	9.91	23.1	20.8	19	9.66	14.1	24.8	12.2	14	66.1	20.5	15.2	17.4	21.6	20	32.3	17.9	17	19.9	9.95	35.3
13-HOTE	6.85	2.81	2.85	5.53	3.86	1.38	3.73	4.45	3.15	5.17	3.39	2.23	3.02	1.7	4.41	3.53	2.34	1.52	6.29	4.69	4.25	1.24	3.91	0.79	1.18	1.13	2.11	2.06	1.62	2.08	1.79	8.88	6.69	3.03	2.76	2.47	0.715	2.08	0.841	1.56	1.58	1.65	3.31	1.95	1.88	2.28	2.49	1.98	2.69	1.36	10.3	1.24	2.96	1.86	2.45	1.19	1.68	0.923	2.15	4.61	2.47	2.54	9.95	2.8	1.92	3.28	1.15	1.38	5.66	1.88	5.56	3.05	7.59	1.74	1.11	2.12	1.35	2.47	2.05	3.28	4.15	2.22	1.74	21.9	4.16	5.2	1.72	1.07	4.82	4.47	1.54	1.14	1.47	1.9	1.1	4.44	2.44	1.92	0.721	1.9	1.79	1.47	4.03	1.15	1.92	1.09	1.04	1.37	2.53	1.83	2.37	1.24	1.42	1.68	1.74	0.726	2.62	0.614	2.17	2.3	2.81	1.12	1.14	1.62	1.26	0.891	7.2	2.51	0.99	1.03	2.17	1.48	4.65	1.58	1.22	2.4	0.827	2.55
15-HETE	3.64	2.27	2.3	6.84	3.04	2.5	2.27	5.67	1.9	3.56	3.58	1.78	1.1	1.82	3.5	2.32	1.39	2.94	1.3	2.26	2.18	1.35	0.897	1.35	1.38	1.32	1.8	2.32	3.54	1.86	1.3	5.33	9.07	1.87	1.38	2.01	1.69	1.62	1.45	2.6	1.65	1.1	2.18	0.98	2.04	2.42	0.986	1.78	1.65	1.06	5.37	1.42	1.9	1.27	1.03	1.48	1.52	1.92	1.58	1.96	1.18	1.38	5.06	1.16	1.21	2.85	1.38	1.17	2.78	1.05	2.28	2.66	2.13	1.06	1.35	1.32	1.16	3.45	2.4	2.2	4.12	1.68	1.42	1.14	3.11	2.38	1.41	0.784	3.03	2.6	1.43	1.49	1.66	1.46	1.28	1.47	1.73	1.89	0.702	3.7	1.84	1.18	2.02	2.16	1.5	1.26	1.48	2.42	2.44	1.05	2.1	1.24	1.24	1.71	1.09	0.884	2.84	0.818	1.37	1.58	1.36	1.08	1.26	1.12	1.64	1.06	1.85	1.94	1.81	1.58	1.82	1.02	2.39	2.84	1.4	1.84	1.31	1.78
12-HETE	4.59	2.88	2.89	6.96	7.29	2.54	2.7	5.65	12.2	3.96	1.97	1.96	6.63	2.08	2.65	1.9	2.76	3.22	3.82	2.42	3.19	1.12	0.874	2.16	1.91	1.23	7.34	4.15	4.98	1.71	5.15	7.99	10.4	25	3.4	3.56	7.1	2.34	2.17	2.7	3.81	1.06	1.99	0.974	11.9	2.31	2.39	1.49	2.36	1.2	7.24	1.53	1.79	0.727	3.3	9.23	1.43	8.02	1.06	22.5	5.56	13.7	11.2	1.44	8.92	1.6	5.89	1.01	8.26	1.49	5.5	10	9.9	1.15	9.28	2.42	1.87	18.7	4.49	2.52	5	2.29	5.18	2.92	9.35	15.5	4.13	2.02	3.67	2.19	1.28	3.47	6.49	6.58	1.35	1.46	7.1	2.16	5.26	5.22	1.49	1.56	3.13	10.9	5.23	1.62	1.74	7.45	12.6	0.683	1.91	2.01	1.19	1.72	2.52	3.79	2.6	0.705	2.36	1.89	0.877	1.28	1.98	1.97	3.06	3.99	3.28	1.36	3.05	4.41	8.16	1.29	4.62	6.56	3.83	1.43	1.59	7.53
9-HETE	2.49	1.17	0.913	6.19	1.55	1.09	1.69	3.85	1	1.76	0.612	0.646	0.35	0.656	0.838	0.774	0.59	0.949	0.41	1.08	0.839	0.771	0.356	0.455	0.561	0.376	0.649	0.458	0.511	0.735	0.481	4.31	7.14	1.28	0.401	0.598	0.522	0.761	0.678	0.451	0.799	0.482	1.5	0.383	0.856	1.1	0.374	0.264	0.652	0.445	4.83	0.405	0.571	0.412	0.351	0.265	0.59	0.402	0.946	0.703	0.458	0.698	3.13	0.54	0.422	0.782	0.533	0.424	1.92	0.582	0.853	1.73	0.692	0.194	0.692	0.494	0.383	1.17	0.838	0.855	2.8	0.959	0.384	0.376	1.06	1.6	0.714	0.295	2.07	0.846	0.731	0.438	0.471	0.805	0.364	0.712	0.627	0.281	0.407	2.71	0.92	0.288	0.742	0.636	0.772	0.471	0.88	0.797	1.17	0.552	1.11	0.488	0.481	0.466	0.632	0.31	0.609	0.333	0.503	0.939	0.615	0.309	0.445	0.456	0.537	0.241	0.692	0.399	1.21	0.376	0.703	0.396	1.85	0.687	0.429	0.919	0.467	0.774
8-HETE	1.98	1.08	1.02	4.64	1.72	1.34	1.6	3.58	0.964	2.32	0.681	1.04	0.502	0.8	0.855	0.913	0.563	0.943	0.619	1.3	1.05	0.865	0.49	0.572	0.713	0.498	0.796	0.659	0.777	1.02	0.476	4.01	6.53	1.13	0.57	0.703	0.641	0.737	0.803	0.753	0.687	0.55	1.2	0.364	0.842	0.868	0.438	0.464	0.832	0.584	4.32	0.519	0.574	0.403	0.414	0.451	0.665	0.69	1	0.824	0.484	0.791	3.37	0.649	0.624	0.887	0.636	0.645	1.7	0.652	1.39	1.69	0.859	0.428	0.674	0.715	0.438	1.2	0.901	0.83	2.59	0.816	0.583	0.464	1.52	1.96	0.868	0.359	2.03	1.02	0.705	0.634	0.66	0.844	0.454	0.857	0.876	0.519	0.48	2.3	0.995	0.529	1.17	0.873	1.03	0.58	1.02	1.11	1.33	0.56	1.16	0.798	0.636	0.698	0.625	0.506	0.703	0.45	0.672	1.02	0.758	0.385	0.537	0.617	0.548	0.517	0.854	0.578	1.21	0.583	0.774	0.497	1.65	0.952	0.494	1.05	0.576	1.4
5-HETE	4.12	2.35	2.47	6.7	4.47	3.78	2.73	6.32	3.25	3.69	2.85	2.4	1.82	3.27	2.91	2.43	1.44	2.81	2.08	2.77	7.33	1.91	1.54	2.05	1.9	1.94	2.27	2.07	2.9	2.38	1.83	7.5	9.5	2.43	2.79	1.98	2.36	1.74	2.04	2.08	6.09	3.05	2.85	1.31	3.54	2.54	1.72	1.05	2.81	1.62	4.9	1.51	2.37	1.19	1.14	1.84	2.05	2.98	1.67	4.32	5.24	2.72	6.69	1.62	1.92	2.54	1.82	2.24	3.91	1.38	2.81	3.19	2.81	1.42	3.02	1.59	1.1	4.5	4.5	2.25	19.2	10.3	2.33	3.22	4.1	3.52	2.47	1.28	4.64	2.31	2.48	1.85	2.35	2.97	1.09	2.38	1.47	1.43	1.06	7.77	6.03	2.15	3.12	2.23	3.02	2.21	2.61	2.64	3.1	1.54	1.59	1.45	1.49	2.37	2.42	1.12	2.02	1.47	1.9	4.3	2.2	1.26	2.38	1.83	1.26	1.39	2.32	1.14	1.92	1.93	2.53	1.39	1.83	3.15	1.34	1.81	1.11	2.14
15-HEPE	0.401	0.269	0.246	1.62	0.483	0.336	0.203	0.974	0.228	0.391	0.594	0.198	0.267	0.209	0.596	0.245	0.172	0.561	0.0804	0.281	0.0482	0.0475	0.11	0.0883	0.0612	0.0707	0.127	0.348	0.661	0.378	0.156	1.02	2.51	0.184	0.332	0.347	0.411	0.726	0.16	0.389	0.579	0.132	0.472	0.225	0.305	0.297	0.315	0.341	0.265	0.529	0.568	0.333	0.472	0.276	0.496	0.215	0.491	0.566	0.56	0.215	0.156	0.115	0.75	0.304	0.165	2.24	0.0972	0.334	0.229	0.179	0.175	1.04	0.28	0.075	0.149	0.183	0.141	0.471	0.256	0.182	0.546	0.174	0.131	0.187	0.389	0.361	0.509	0.106	0.364	0.4	0.127	0.13	0.146	0.143	0.133	0.247	0.303	1.45	0.0379	0.337	0.231	0.0745	0.175	0.274	0.438	0.16	0.194	0.511	0.238	0.284	0.204	0.104	0.085	0.422	0.112	0.147	0.468	0.105	0.174	0.202	0.444	0.129	0.13	0.0751	0.184	0.0812	0.245	0.2	0.422	0.118	0.612	0.259	0.283	0.452	0.212	0.618	0.175	0.246
12-HEPE	0.416	0.153	0.293	1.54	0.561	0.371	0.263	0.856	0.592	0.345	0.187	0.18	0.549	0.127	0.179	0.109	0.131	0.103	0.0958	0.184	0.228	0.091	0.112	0.147	0.0811	0.139	0.434	0.217	0.0862	0.131	0.152	1.03	2.23	0.401	0.356	0.231	0.521	0.436	0.17	0.133	0.399	0.0547	0.289	0.204	0.69	0.117	0.269	0.103	0.12	0.438	0.409	0.0459	0.142	0.147	0.604	0.273	0.254	0.627	0.173	1.53	0.129	0.35	0.846	0.241	0.296	1.13	0.112	0.282	0.329	0.0839	0.277	1.75	0.382	0.0355	0.268	0.131	0.1	0.276	0.233	0.17	0.519	0.139	0.164	0.0996	0.611	0.511	0.866	0.0855	0.336	0.186	0.098	0.138	0.151	0.289	0.0851	0.119	0.451	0.851	0.079	0.262	0.157	0.0403	0.177	0.22	0.594	0.117	0.158	0.544	0.473	0.243	0.0892	0.153	0.0813	0.276	0.113	0.104	0.188	0.0772	0.167	0.256	0.261	0.055	0.0983	0.0778	0.109	0.222	0.208	0.12	0.6	0.255	1.11	0.516	0.286	0.234	0.186	0.447	0.0899	0.226
9-HEPE	0.367	0.13	0.174	1.47	0.389	0.31	0.294	0.84	0.329	0.422	0.127	0.187	0.114	0.179	0.127	0.165	0.112	0.127	0.178	0.23	0.119	0.145	0.0923	0.089	0.0759	0.0823	0.0184	0.0401	0.0624	0.124	0.138	1.04	2.64	0.156	0.306	0.141	0.191	0.333	0.156	0.071	0.303	0.118	0.301	0.201	0.29	0.0827	0.166	0.0717	0.0951	0.351	0.469	0.0412	0.0536	0.244	0.214	0.0754	0.174	0.176	0.384	0.247	0.0696	0.0912	0.724	0.214	0.101	1.13	0.069	0.213	0.128	0.0439	0.162	0.744	0.106	0.0301	0.0836	0.126	0.0622	0.148	0.0165	0.143	0.477	0.203	0.109	1.45	0.23	0.342	0.567	0.0688	0.32	0.203	0.173	0.0517	0.0703	0.167	0.0364	0.166	0.137	0.464	0.0623	0.306	0.299	0.0573	0.189	0.0594	0.513	0.107	0.189	0.236	0.0919	0.286	0.114	0.105	0.0642	0.188	0.0427	0.074	0.0937	0.0718	0.0295	0.223	0.346	0.0542	0.105	0.0368	0.0647	0.0953	0.217	0.0899	0.515	0.109	0.458	0.274	0.287	0.0987	0.0795	0.598	0.0895	0.179
5-HEPE	0.92	0.304	0.62	2.09	0.867	1.2	0.567	1.35	0.821	0.777	0.822	1.11	0.467	0.603	0.802	0.282	0.124	0.313	0.161	0.454	0.996	0.446	0.439	0.315	0.269	0.366	0.399	0.522	0.292	0.65	0.443	1.75	2.69	0.0481	1.03	0.513	0.773	0.839	0.533	0.558	1.41	0.487	0.484	0.71	0.672	0.436	0.687	0.113	0.279	1.3	0.408	0.178	0.476	0.645	0.579	0.25	1.05	0.759	0.692	0.874	0.142	0.357	1.87	0.738	0.356	1.87	0.248	1.52	0.436	0.196	0.447	1.38	0.367	0.133	0.352	0.41	0.163	0.321	0.855	0.365	1.53	0.771	0.436	0.0964	0.836	0.533	1.35	0.171	0.614	0.808	0.53	0.316	0.182	0.428	0.259	0.815	0.519	1.32	0.112	0.78	0.628	0.322	0.57	0.503	1.18	0.478	0.726	1.09	0.375	1	0.187	0.582	0.271	1.19	0.31	0.181	0.466	0.524	0.385	0.709	1.13	0.277	0.506	0.193	0.288	0.305	0.583	0.26	0.839	0.473	1.09	1.36	0.37	0.534	0.257	0.818	0.249	0.363
17-HDoHE	4.32	2.43	2.19	15.7	2.96	2	1.53	6.8	2.45	4.69	3	1.02	2.74	1.99	2.64	2.63	1.83	1.45	1.62	2.74	1.58	1.08	1.34	0.779	0.899	1.33	0.735	1.26	1.38	2.46	1.06	7.3	19.7	2.05	1.62	1.78	1.88	3.89	1.15	1.63	1.99	0.772	1.95	2.18	1.34	2.14	1.49	1.3	0.602	2.13	5.82	0.94	2.59	2.23	1.84	1.05	1.8	2.86	2.22	2.08	1.16	2.07	10.5	1.98	1.69	7.38	1.97	2.14	2.54	1.32	1.73	5.91	1.54	0.84	0.737	0.944	0.507	1.74	1.16	1.53	3.9	1.54	1.35	2.03	2.78	1.97	2.12	0.384	2.78	1.74	0.745	0.952	0.874	1.54	0.914	1.95	1.68	4.22	0.545	1.74	2.76	0.667	1.25	0.978	2.71	0.905	1.05	2.11	2.03	1.87	1.72	0.871	0.584	1.42	1.39	0.768	2.14	0.603	0.812	1.78	2.07	0.892	0.226	0.707	1.25	0.458	2.14	1.23	2.43	0.932	3.16	2.49	4.8	2.32	2.05	5.6	1.38	0.725
14-HDoHE	2.23	0.99	1.52	7.16	1.51	1.38	1.29	4.17	3.8	2.38	0.827	0.763	3.08	0.876	1.16	0.663	1.01	0.657	0.712	0.942	1.06	0.526	0.386	0.266	0.504	0.485	2.3	0.776	0.551	0.651	0.731	4.14	10.7	1.37	1.2	0.669	1.43	1.45	0.839	0.641	0.851	0.206	0.868	0.583	1.25	0.542	0.762	0.369	0.645	1.08	2.72	0.285	0.453	0.624	1.28	1.15	0.524	2.1	0.805	6.91	0.76	2.49	5.37	0.924	2.08	2.9	0.599	0.732	1.7	0.526	0.694	6.06	1.88	0.305	1.09	0.612	0.336	1.74	1.11	1.25	2.68	1	0.643	0.404	2.43	1.54	1.92	0.391	1.63	0.985	0.272	0.564	0.663	1.49	0.555	0.32	1.63	1.22	0.428	0.872	0.673	0.253	0.535	1.02	2.71	0.282	0.693	1.44	1.99	0.874	0.771	0.737	0.381	0.604	0.926	0.597	0.672	0.243	0.386	0.775	0.636	0.289	0.143	0.389	0.364	0.758	0.768	0.217	1.37	0.862	2.33	1.16	1.51	0.629	1.34	1.41	0.309	0.419
4-HDoHE	1.88	1.01	1.05	5.87	1.17	1.43	1.13	3.71	1.44	2.88	0.74	0.608	0.984	1.05	0.841	0.95	0.833	0.56	0.511	1.26	1.34	0.702	0.599	0.236	0.576	0.51	0.602	0.344	0.515	0.814	0.503	4.15	8.78	1.05	1.09	0.427	0.679	1.53	0.743	0.394	2.06	0.486	1.01	0.71	0.703	0.57	0.937	0.21	0.527	0.966	2.37	0.297	0.57	0.626	0.901	0.275	0.645	0.691	0.978	1.06	0.994	0.832	4.28	0.992	0.749	2.17	0.632	1.05	1.15	0.514	0.526	2.63	0.68	0.188	0.371	0.467	0.225	0.81	0.493	0.906	3.94	1.53	0.472	0.92	1.36	1.21	1.27	0.251	1.74	0.782	0.245	0.278	0.494	0.925	0.545	0.575	0.591	0.845	0.315	0.953	1.77	0.368	0.478	0.662	1.61	0.292	0.914	0.784	1	1.35	0.774	0.62	0.535	0.653	0.776	0.66	0.607	0.411	0.462	1.25	1.21	0.482	0.273	0.346	0.431	0.579	1.09	0.3	1.11	0.375	1.81	1.41	1.9	0.722	0.651	2.15	0.556	0.457
9_10-EpO	8.43	5.27	9.89	8.62	10.1	6.99	5.41	8.68	8.26	6.25	7.81	6.28	8.24	9.8	7.26	5.39	4.12	4.35	5.96	7.93	9.76	6.29	7.74	6	7.16	7.48	10.1	11.9	7.51	8.46	8.87	9.45	11.1	3.11	8.94	14.3	7.4	5.44	7.28	5.59	6.74	6.51	4.84	8.17	8.06	6.01	8.1	4.73	7.67	7.33	3.08	5.4	7.77	6.3	5.65	8.27	6.69	9.55	4.31	10.5	3.74	6.9	8.23	8.4	7.23	10.2	8.04	12.3	11.6	4.12	10.8	8.72	11.5	16.1	14	5.38	6.57	4.96	11.6	11.8	8.8	9.34	6.35	6.74	9.63	7.98	7.65	7.87	8.59	7.16	10.9	7.84	6.25	8.85	7.04	7.68	6.26	8.02	2.51	6.42	3.32	7.45	6.72	6.35	7.44	10.9	9.45	9.01	9.1	9.62	5.3	5.03	7	11	6.97	4.99	6.23	5.26	13.8	7.14	22	6.41	10.2	8.02	7.48	14.8	12.8	7.58	7.93	17.8	13.2	7.89	7.86	11.7	13.2	5.86	8.22	7
12(13)-EpOME	7.47	6.32	6.54	5.34	6.35	3.99	3.95	9.01	5.28	5.35	5.07	6.15	6.1	4.22	8.81	8.33	2.58	3.4	5.57	7.92	10.5	6.22	10.1	4.2	3.94	4.78	5.88	5.48	3.42	3.18	5.21	4.9	5.91	3.33	6.94	4.93	2.35	3.4	2.74	4.43	2.52	4.24	2.71	4.57	4.15	2.56	6.01	6.53	5.52	7.56	5.33	2.53	7.34	4.61	6.31	2.64	2.23	3.5	2.65	7.51	2.25	3.2	6.96	5.35	5.17	5.79	3.28	5.53	11.7	2.01	14.9	3.29	17.5	5.49	4.28	2.53	3.29	3.75	3.66	4.98	3.91	4.52	2.88	11.8	8.14	5.09	3.56	3.27	3.58	8.09	7.68	4.28	2.4	3.83	5.04	7.49	5.9	4.87	1.52	3.53	1.95	4.83	7.87	2.75	2.95	6.74	2.59	4.04	3.85	5.95	2.95	3.79	3.34	2.95	3.48	2.22	3.53	2.07	6.34	3.53	7.4	3.2	7.08	3.84	2.86	4.04	15.4	7.64	2.48	5.9	4	10.9	4.42	2.93	3.67	3.06	3.18	6.42
9(10)-EpOME	7.7	3.3	4.99	5.17	5.95	3.73	3.09	8.94	3.46	5.25	3.74	3.58	4.86	3.74	5.64	3.31	1.93	2.28	3.98	4.63	9.56	4.43	5.38	2.12	3.68	3.82	4.32	5.17	2.89	1.94	3.84	5.38	5.36	1.68	5.37	3.82	1.82	3.07	2.26	2.46	1.84	3.16	2.52	3.38	3.46	2.16	5.36	2.38	4.16	3.48	3.84	1.82	3.6	2.35	4.08	1.7	1.75	2.58	1.82	5.92	1.51	2.44	3.83	4.88	3.96	4.01	1.58	4.21	12.4	1.3	5.78	2.53	7.01	3.67	3.09	1.44	1.96	2.07	3.21	3.97	3.79	3.54	1.57	9.31	8.4	3.88	2.59	2.57	3.59	5.82	4.64	3.02	1.82	3.4	2.75	4.32	3.06	2.87	1.14	2.67	1.21	3.1	3.73	2.31	2.02	4.46	2.13	3.55	3.46	4.37	2.23	1.93	2.75	2.85	2.73	1.95	2.13	1.48	5.05	2.87	5.8	1.28	3.9	3.43	2.21	4.53	8.18	2.91	1.93	4.22	3.26	3.07	3.52	2.11	3.02	2.25	2.49	3.91
15(16)-EpODE	3.14	4.83	2.93	1.23	1.85	1.15	1.48	2.01	2.76	2.3	3.45	6.05	2.95	1.94	9.81	6.79	1.35	1	4.39	5.69	6.8	2.4	10.9	1.52	1.71	2.82	3.27	4.46	2.37	2.12	1.95	1.11	0.839	1.63	2.89	3.73	0.853	1.41	1.43	2.32	1.16	2.4	1.09	3.39	1.19	1.02	4.03	3.85	4.9	3.46	2.12	1.51	5.93	6	2.45	1.47	1.16	1.34	1.89	3.09	0.913	1.46	6.33	4.14	3.58	3.94	1.06	4.24	3.38	1.06	13.8	0.903	17.2	2.25	0.926	1.62	0.975	1.23	1.49	3.04	1.66	3.01	1.78	2.68	4.41	4.98	1.92	2.07	1.15	7.35	4.67	2.16	1.15	1.3	1.67	10.5	5.4	4.14	0.877	1.79	1.41	4.28	10.8	1.53	2	3.28	1.77	2.31	1.22	2.63	1.39	2.6	2.3	2.56	1.88	1.58	2.26	1.09	3.8	1.41	9.85	1.22	4.72	4.58	1.31	2.12	23.8	7.58	1.01	5.03	2.52	5.62	1.59	2.63	1.72	1.68	0.778	9.39
12(13)-EpODE	0.597	0.355	0.281	0.16	0.327	0.175	0.117	0.378	0.0679	0.19	0.225	0.259	0.201	0.191	0.548	0.306	0.108	0.123	0.294	0.33	0.403	0.226	0.725	0.0862	0.152	0.131	0.137	0.31	0.13	0.0876	0.13	0.157	0.125	0.153	0.169	0.179	0.0649	0.158	0.0556	0.124	0.0753	0.112	0.287	0.227	0.151	0.0907	0.21	0.243	0.163	0.189	0.215	0.0897	0.305	0.103	0.122	0.0784	0.0756	0.121	0.111	0.239	0.0656	0.106	0.353	0.215	0.198	0.362	0.0192	0.108	0.602	0.0719	1.05	0.144	1.24	0.201	0.0766	0.0685	0.0683	0.15	0.0809	0.141	0.151	0.126	0.116	0.261	0.794	0.42	0.253	0.119	0.129	0.495	0.261	0.0642	0.0579	0.154	0.0949	0.263	0.356	0.347	0.0311	0.107	0.0456	0.0948	0.644	0.0823	0.0927	0.459	0.237	0.191	0.195	0.158	0.145	0.157	0.105	0.123	0.112	0.0679	0.186	0.0395	0.369	0.184	0.286	0.13	0.169	0.148	0.119	0.272	1.81	0.521	0.0918	0.243	0.228	0.346	0.24	0.14	0.158	0.173	0.122	0.58
9(10)-EpODE	2.01	0.587	0.911	0.615	1.19	0.431	0.62	1.18	0.322	0.531	0.919	0.854	0.547	0.601	1.61	0.458	0.341	0.171	0.832	0.825	1.73	0.475	0.662	0.381	0.311	0.543	0.602	0.786	0.459	0.408	0.49	0.661	0.388	0.308	1.06	0.573	0.169	0.392	0.277	0.537	0.23	0.365	0.476	0.671	0.566	0.484	0.864	0.322	0.824	0.482	0.529	0.228	0.589	0.504	0.545	0.187	0.312	0.258	0.25	1.13	0.249	0.42	1.01	0.681	0.613	0.508	0.216	0.573	1.45	0.342	1.3	0.319	3.97	0.507	0.285	0.281	0.235	0.159	0.354	0.595	0.462	0.788	0.272	2.39	2.23	0.58	0.42	0.401	0.54	1.51	0.799	0.266	0.341	0.45	0.304	1.44	0.388	0.363	0.127	0.349	0.22	0.595	1.12	0.37	0.426	0.595	0.26	0.543	0.689	0.466	0.44	0.455	0.526	0.906	0.701	0.318	0.534	0.168	0.806	0.628	0.837	0.292	0.512	0.829	0.381	0.763	5.82	0.808	0.297	0.972	0.829	0.772	0.763	0.679	0.588	0.394	0.422	0.822
14(15)-EpETrE	0.56	0.351	0.334	0.552	0.454	0.45	0.333	0.697	0.192	0.36	0.135	0.144	0.134	0.137	0.424	0.211	0.0751	0.215	0.185	0.203	0.253	0.391	0.242	0.125	0.165	0.148	0.169	0.216	0.255	0.118	0.234	0.446	0.743	0.21	0.203	0.171	0.204	0.242	0.25	0.12	0.111	0.169	0.397	0.184	0.223	0.18	0.159	0.12	0.214	0.152	0.363	0.139	0.202	0.134	0.0693	0.0845	0.12	0.188	0.103	0.247	0.305	0.0837	0.0693	0.188	0.0987	0.138	0.161	0.159	0.424	0.133	0.143	0.171	0.21	0.0535	0.129	0.162	0.179	0.174	0.147	0.135	0.331	0.0794	0.119	1	0.681	0.453	0.262	0.228	0.422	0.31	0.248	0.189	0.233	0.154	0.24	0.156	0.155	0.211	0.197	0.228	0.115	0.107	0.161	0.331	0.239	0.407	0.402	0.506	0.337	0.26	0.259	0.165	0.2	0.178	0.187	0.254	0.145	0.211	0.272	0.247	0.212	0.222	0.139	0.259	0.434	0.411	0.315	0.147	0.492	0.17	0.381	0.168	0.396	0.316	0.134	0.227	0.506	0.283
11(12)-EpETrE	0.422	0.15	0.173	0.232	0.253	0.199	0.129	0.451	0.0917	0.165	0.0535	0.082	0.0695	0.0556	0.142	0.118	0.0466	0.0826	0.148	0.0893	0.155	0.177	0.102	0.0823	0.0833	0.0535	0.0716	0.119	0.061	0.0469	0.094	0.247	0.288	0.0595	0.138	0.116	0.0501	0.0741	0.0915	0.0775	0.0506	0.0693	0.267	0.137	0.166	0.0983	0.08	0.0624	0.111	0.0805	0.177	0.0569	0.103	0.0276	0.0329	0.0312	0.0687	0.068	0.0499	0.136	0.0696	0.0671	0.107	0.167	0.122	0.0838	0.0514	0.0743	0.27	0.0226	0.0828	0.0909	0.0741	0.0481	0.0785	0.039	0.0713	0.103	0.0722	0.0603	0.193	0.0684	0.061	0.266	0.461	0.259	0.157	0.112	0.161	0.161	0.122	0.0707	0.0736	0.132	0.0715	0.0904	0.0928	0.0666	0.053	0.0711	0.0536	0.0329	0.0736	0.138	0.076	0.503	0.269	0.205	0.156	0.0893	0.144	0.0613	0.0818	0.114	0.0662	0.0441	0.039	0.0686	0.265	0.109	0.133	0.0577	0.0916	0.0734	0.138	0.278	0.21	0.127	0.181	0.12	0.174	0.0959	0.142	0.129	0.0627	0.0942	0.142	0.242
8(9)-EpETrE	0.403	0.162	0.191	0.253	0.276	0.232	0.259	0.621	0.0934	0.211	0.0575	ND	ND	0.106	0.191	0.106	0.0435	0.0715	0.179	0.0777	0.312	0.208	0.0712	0.0203	0.115	0.0646	0.0879	0.192	0.0665	0.0631	0.0786	0.297	0.6	0.0637	0.131	0.134	0.124	0.261	0.149	0.0444	0.123	0.0889	0.329	0.15	0.255	0.181	0.116	0.113	0.134	0.0944	0.25	0.112	0.126	0.0503	0.0703	0.148	0.1	0.078	0.0623	0.275	0.0535	0.0965	0.142	0.14	0.171	0.117	0.0409	0.085	0.249	0.114	0.122	0.0598	0.0333	0.0549	0.181	0.0599	0.142	0.029	0.139	0.067	0.249	0.0762	0.142	1.06	0.373	0.218	0.155	0.093	0.0821	0.244	0.0854	0.0834	0.0997	0.143	0.0755	0.0846	0.134	0.133	0.024	0.108	0.0708	0.0157	0.0923	0.23	0.111	0.465	0.387	0.231	0.097	0.171	0.158	0.0595	0.0636	0.136	0.0724	0.0896	0.128	0.0689	0.225	0.136	0.14	0.0309	0.154	0.0415	0.136	0.298	0.34	0.121	0.166	0.159	0.242	0.136	0.191	0.0773	0.108	0.111	0.15	0.185
12(13)-Ep-9-KODE	15.8	8.87	1.16	5.39	2.82	3.56	7.65	8.23	1.18	6.23	6.03	1.87	6.36	2.92	18.5	6.85	4.05	2.12	2.91	2.09	11.5	2.16	2.11	0.825	2.67	2.53	2.95	5.47	6.81	1.18	4.23	8.62	3.68	4.8	9.87	4.59	1.67	2.12	3.77	4.88	1.88	2.18	4.92	1.09	0.989	4.81	6.13	2.74	1.69	3.62	5.4	1.31	0.517	2.34	5.6	1.22	0.706	2.51	1.87	5.24	3.95	3.56	2.17	2.03	4.11	5.2	0.604	1.18	9.11	3.9	11.7	1.76	1.91	2.13	1.31	3.05	1.23	2.14	1.78	5.22	4.03	1.54	2.97	4.2	2.13	4.21	1.05	4.01	6.38	3.93	1.14	3.69	4	2.66	2.23	5.82	2.43	3.82	1.66	1.64	1.05	3.82	6.06	1.06	1.67	1.14	2.49	1.41	2.67	4.11	1.99	1.43	2.02	0.727	1.91	2.01	2.46	3.03	3.29	3.14	0.905	0.189	1.31	1.51	1.72	1.73	3.14	3.82	2.62	3.01	3	4.81	1.54	4.08	2.01	2.23	2	4.17
13-KODE	18.4	6.01	1.73	8.12	3.3	1.92	5.76	3.39	1.9	6.24	1.38	1.37	2.63	2.22	7.43	1.7	0.994	1.18	4.18	2.32	3.96	1.31	1.03	0.645	1.19	1.09	0.884	1.9	1.85	2.02	1.62	7.51	5.13	3.15	2.62	2.05	0.834	1.27	0.88	2.15	1.19	1.01	3.18	1.61	1.48	4.04	3.41	1.47	1.46	1.52	8.3	1.48	1.36	1.42	3.16	1.67	0.953	1.2	2.27	3.47	1.28	1.16	4.34	2.38	1.69	2.27	1.12	1.08	7.36	2.09	6.24	2.64	1.94	0.915	2.09	2.3	1.54	1.98	2.19	5.32	2.69	1.84	1.37	27.9	2.92	4.28	2.33	1.87	4.99	3.83	1.82	2	1.91	2.74	0.708	2.72	2.64	1.86	1.24	2.25	2.16	1.4	2.52	0.989	1.64	1.51	1.29	1.76	3.68	1.55	2.14	1.33	1.24	1.56	1.32	1.34	1.48	1.68	1.85	2.24	1.55	1.02	1.19	2.47	1.13	2.05	3.22	1.97	2.45	3.21	3.48	2.11	3.48	2.61	2.15	2.36	1.58	3.45
9-KODE	34.4	14.5	4.34	17.9	8.46	3.96	13.4	10.9	3.96	12.2	3.04	2.56	6.19	5.29	17.2	4.51	3.49	2.74	10.8	5.42	6.45	3.3	2.95	2.04	2.67	2.59	2.39	2.99	3.99	2.8	2.93	20.4	13.7	5.76	5.12	4.22	1.34	3.68	1.67	5.32	3.33	2.32	9.03	5.21	3.88	7.7	6.84	3.31	3.32	4.52	17.8	4.58	4.19	5.83	6.41	2.67	2.11	3.03	3.91	6.99	6.17	3.98	9.83	8.42	4.66	5.35	2.39	4.94	17.7	4.08	20	5.96	9.05	2.31	4.85	5.27	5.88	6.06	6.06	11	6.23	3.49	3.96	60.7	6.57	12.5	3.06	11.3	10.5	9.03	4.79	4.86	4.92	5.39	3.4	8.09	5.92	3.36	3.26	5.38	3.78	3	9.24	3.36	5.33	3.93	4.46	2.76	4.59	6.41	5.39	3.74	3.58	3.49	3.76	4.06	3.45	9.75	3.79	4.41	4.28	2.52	3.38	5.52	3.79	3.74	11.2	4.57	4.62	8.23	6.59	6.37	7.87	5.64	5.07	5.55	3.77	10.1
5-KETE	0.512	0.222	0.121	0.355	0.228	0.203	0.232	0.364	0.193	0.237	0.0522	0.0795	0.0555	0.105	0.257	0.0755	0.0106	0.0876	0.0749	0.112	0.252	0.159	0.0779	0.062	0.063	0.0384	0.0487	0.0946	0.0365	0.0772	0.104	0.309	0.467	0.148	0.0812	0.0603	0.0652	0.0818	0.058	0.104	0.295	0.116	0.357	0.128	0.246	0.225	0.167	0.0888	0.122	0.0235	0.293	0.0747	0.0549	0.0631	0.0698	0.0716	0.0512	0.116	0.104	0.249	0.224	0.071	0.344	0.15	0.1	0.198	0.0802	0.12	0.367	0.0714	0.167	0.184	0.115	0.0511	0.104	0.0587	0.0394	0.228	0.13	0.123	0.623	0.368	0.142	0.252	0.37	0.403	0.175	0.134	0.372	0.206	0.0887	0.099	0.107	0.187	0.05	0.133	0.0674	0.108	0.0781	0.0535	0.28	0.0952	0.12	0.115	0.13	0.257	0.207	0.144	0.223	0.0889	0.129	0.152	0.0781	0.11	0.0687	0.0632	0.121	0.106	0.311	0.325	0.161	0.0863	0.114	0.133	0.0972	0.366	0.381	0.119	0.23	0.178	0.246	0.0971	0.186	0.199	0.0573	0.158	0.0941	0.273
10-Nitrooleate	3.02	2.97	3.46	4.43	4.35	2.97	3.59	3.08	3.13	3.62	2.45	2.96	6.09	2.53	5.39	3.14	3.26	3.88	4.29	2.55	3.43	3.42	2.88	2.43	3.91	1.91	1.99	3.65	4.75	0.971	1.67	1.14	5.27	0.985	2.34	3.43	1.49	1.8	1.81	4.27	4.05	2.64	2.9	4.58	2.72	1.24	6.52	4.44	3.09	4.13	1.38	4.12	3.6	3.24	8.04	2.72	2.29	1.66	0.474	2.93	1.21	4.49	2.19	2.72	2.07	1.46	1.13	2.81	1.51	0.94	0.936	2.76	3.26	1.63	2.1	0.943	5.48	3.92	2.38	1.43	1.57	1.39	2.49	1.99	6.07	2.37	3.49	4.27	2.27	4.24	4.56	26	2.12	0.937	2.04	6.11	4.24	3.97	1.96	2.63	1.34	1.49	1.4	8.4	3.4	5.5	4.68	2.47	2.03	3.08	4.37	3.45	2.6	3.19	1.75	2.91	1.95	4.39	1.09	5.7	2.11	2.4	1.65	2.59	4.15	1.62	4.76	3.61	10	1.86	2.81	2.99	1	5.93	0.808	1.28	3.89	2.09
OEA	2.81	2.86	3.66	3.25	2.73	2.13	2.73	3.55	3.06	2.36	3.66	2.38	2.99	4.15	3.17	2.76	1.31	2.88	4.58	3.22	4.87	4.71	4.41	2.97	6.51	5.36	4.73	3.45	2.77	2.53	3.9	2.27	1.97	4	5.55	3.17	3.7	3.1	2.49	3.36	2.97	4.28	2.09	4.15	3.25	4.34	4.21	1.98	7.79	3.45	2.33	2.24	3.75	2.93	3.8	3.03	3.55	4.23	1.95	7.69	2.49	4.28	3.54	2.96	4.42	3.08	3.14	3.37	4.03	2.97	3.32	5.93	3.56	5.09	4.48	2.61	10.2	4.17	4.78	5.8	2.85	4.69	2.02	5.26	4.9	2.91	4.15	3.83	4.27	2.52	4.63	5.59	5.82	5.03	2.48	6.12	3.07	4.11	2.41	3.68	2.69	4.7	2.78	3.24	4.43	4.81	4.47	6.6	4.93	4.56	2.05	5.02	4.48	4.75	4.59	2.91	3.1	3.53	4.9	3.07	3.18	4.01	3.25	3.39	2.13	6.4	4.23	2.86	3.74	8.41	4.74	3.23	1.72	5.01	2.79	2.97	2.44	2.26
MS_METABOLITE_DATA_END
#METABOLITES
METABOLITES_START
metabolite_name	HMDB ID	InChIKey	PubChem CID	KEGG
6-keto PGF1a	HMDB02886	KFGOFTHODYBSGM-ZUNNJUQCSA-N	5280888	C05961
PGF2a	HMDB01139	PXGPLTODNUVGFL-UAAPODJFSA-N	5283078
15-deoxy PGJ2	HMDB05079	VHRUMKCAEVRUBK-GODQJPCRSA-N	5311211	C14717
PGF2a EA	HMDB13628	XCVCLIRZZCGEMU-FPLRWIMGSA-N	53481911
11-HETE	HMDB04682	GCZRCCHPLVMMJE-RSPKXIRXSA-N	5312981
9_12_13-TriHOME	HMDB04708	MDIUMSLCYIJBQC-MVFSOIOZSA-N	9858729	C14833
9_10-e-DiHO		VACHUYIREGFMSP-SJORKVTESA-N	441460
12_13-DiHOME	HMDB04705	CQSLTKIXAJTQGA-FLIBITNWSA-N	10236635	C14829
9_10-DiHOME	HMDB04704	XEBKSQSGNGRGDW-YFHOEESVSA-N	9966640	C14828
15_16-DiHODE	HMDB10208	LKLLJYJTYPVCID-OHPMOLHNSA-N	16061068
12_13-DiHODE	HMDB10201	RGRKFKRAFZJQMS-OOHFSOINSA-N	16061067
9_10-DiHODE	HMDB10221	QRHSEDZBZMZPOA-ZJSQCTGTSA-N	16061066
14_15-DiHETrE	HMDB02265	SYAWGTIVOGUZMM-ILYOTBPNSA-N	5283147	C14775
11_12-DiHETrE	HMDB02314	LRPPQRCHCPFBPE-KROJNAHFSA-N	5283146	C14774
8_9-DiHETrE	HMDB02311	DCJBINATHQHPKO-TYAUOURKSA-N	5283144	C14773
5_6-DiHETrE	HMDB02343	GFNYAPAJUNPMGH-QNEBEIHSSA-N	5283142	C14772
14_15-DiHETE	HMDB10204	BLWCDFIELVFRJY-QXBXTPPVSA-N	16061119
19_20-DiHDoPA	HMDB10214	FFXKPSNQCPNORO-MBYQGORISA-N	16061148
13-HODE	HMDB04667	HNICUWMFWZBIFP-IRQZEAMPSA-N	6443013	C14762
9-HODE	HMDB10223	NPDSHTNEKLQQIJ-SIGMCMEVSA-N	5282945
13-HOTE	HMDB10203	KLLGGGQNRTVBSU-JDTPQGGVSA-N	10469728
15-HETE	HMDB03876	JSFATNQSLKRBCI-VAEKSGALSA-N	5280724	C04742
12-HETE	HMDB06111	ZNHVWPKMFKADKW-FYMOKONMSA-N	5312983
9-HETE	HMDB10222	KATOYYZUTNAWSA-DLJQHUEDSA-N	5312978
8-HETE	HMDB04679	NLUNAYAEIJYXRB-VYOQERLCSA-N	5283154	C14776
5-HETE	HMDB11134	KGIJOOYOSFUGPC-JGKLHWIESA-N	5280733	C04805
15-HEPE	HMDB10209	UDXLGBLAJBYLSZ-XBCQTNLFSA-N	53480357
12-HEPE	HMDB10202	MCRJLMXYVFDXLS-QGQBRVLBSA-N	10041593
9-HEPE	HMDB60053	OXOPDAZWPWFJEW-FPRWAWDYSA-N	5283187
5-HEPE	HMDB05081	FTAGQROYQYQRHF-FCWZHQICSA-N	6439678
17-HDoHE	HMDB10213	SWTYBBUBEPPYCX-VIIQGJSXSA-N	6439179
14-HDoHE	HMDB60044	ZNEBXONKCYFJAF-BGKMTWLOSA-N	11566378
4-HDoHE	HMDB60049	IFRKCNPQVIJFAQ-JGDWKEERSA-N	53394255
9_10-EpO		IMYZYCNQZDBZBQ-UHFFFAOYSA-N	15868
12(13)-EpOME	HMDB04702	CCPPLLJZDQAOHD-FLIBITNWSA-N	5356421
9(10)-EpOME	HMDB04704	XEBKSQSGNGRGDW-YFHOEESVSA-N	9966640	C14828
15(16)-EpODE	HMDB10206	HKSDVVJONLXYKL-OHPMOLHNSA-N	16061062
12(13)-EpODE	HMDB10200	BKKGUKSHPCTUGE-OOHFSOINSA-N	16061061
9(10)-EpODE	HMDB10220	JTEGNNHWOIJBJZ-ZJSQCTGTSA-N	16061060
14(15)-EpETrE	HMDB04693	WLMZMBKVRPUYIG-LTCHCNGXSA-N	11954058	C14813
11(12)-EpETrE	HMDB10409	DXOYQVHGIODESM-IQCOFVSKSA-N	53480479
8(9)-EpETrE	HMDB02232	DBWQSCSXHFNTMO-TYAUOURKSA-N	5283203	C14769
12(13)-Ep-9-KODE	HMDB13623	RCMABBHQYMBYKV-BUHFOSPRSA-N	5283007
13-KODE	HMDB04668	JHXAZBBVQSRKJR-BSZOFBHHSA-N	6446027	C14765
9-KODE	HMDB04669	LUZSWWYKKLTDHU-ZJHFMPGASA-N	9839084	C14766
5-KETE	HMDB10217	MEASLHGILYBXFO-XTDASVJISA-N	5283159	C14732
10-Nitrooleate	---	WRADPCFZZWXOTI-UHFFFAOYSA-N	53394576
OEA	HMDB02088	BOWVQLFMWHZBEF-KTKRTIGZSA-N	5283454
METABOLITES_END
#END