#METABOLOMICS WORKBENCH blfitz_20181007_152720_mwtab.txt DATATRACK_ID:1529 STUDY_ID:ST001069 ANALYSIS_ID:AN001750 PROJECT_ID:PR000716 VERSION 1 CREATED_ON October 9, 2018, 6:20 pm #PROJECT PR:PROJECT_TITLE Evaluation of TB Treatment Response Biomarkers PR:PROJECT_TYPE Directed MS analysis PR:PROJECT_SUMMARY Directed MS analysis of promising treatment response biomarkers in TB patient PR:PROJECT_SUMMARY urine. PR:INSTITUTE Colorado State University PR:DEPARTMENT MIP PR:LABORATORY Belisle PR:LAST_NAME Fitzgerald PR:FIRST_NAME Bryna PR:ADDRESS 3185 Rampart Rd, Fort Collins, CO, 80521, USA PR:EMAIL blfitz@colostate.edu PR:PHONE 9704918905 PR:FUNDING_SOURCE NIH U01 AI-115619 #STUDY ST:STUDY_TITLE Evaluation of Seryl-leucine core 1 O-glycosylated peptide (SLC1G) in TB patient ST:STUDY_TITLE urine ST:STUDY_SUMMARY Previous work detected an uncharacterized urine metabolite with a molecular mass ST:STUDY_SUMMARY of 874.3547 Da that showed promise as a biomarker for successful TB treatment. ST:STUDY_SUMMARY Using mass spectrometry combined with enzymatic digestions, the metabolite was ST:STUDY_SUMMARY structurally characterized as a seryl-leucine core 1 O-glycosylated peptide ST:STUDY_SUMMARY (SLC1G) of human origin. Examination of SLC1G in urine revealed a significant ST:STUDY_SUMMARY abundance increase in individuals with active TB versus their household contacts ST:STUDY_SUMMARY and healthy controls. Moreover, differential decreases in SLC1G levels were ST:STUDY_SUMMARY observed by week-one in TB patients during successful treatment versus those ST:STUDY_SUMMARY that failed treatment. The SLC1G levels also associated with clinical parameters ST:STUDY_SUMMARY used to measure bacterial burden (GeneXpert) and inflammation (PET-CT). These ST:STUDY_SUMMARY results demonstrate the importance of metabolite identification and provide ST:STUDY_SUMMARY strong evidence for applying SLC1G as a biomarker of TB treatment response. ST:INSTITUTE Colorado State University ST:LAST_NAME Fitzgerald ST:FIRST_NAME Bryna ST:ADDRESS 3185 Rampart Rd ST:EMAIL blfitz@colostate.edu ST:PHONE 9704918905 #SUBJECT SU:SUBJECT_TYPE Human SU:SUBJECT_SPECIES Homo sapiens SU:TAXONOMY_ID 9606 #SUBJECT_SAMPLE_FACTORS: SUBJECT(optional)[tab]SAMPLE[tab]FACTORS(NAME:VALUE pairs separated by |)[tab]Additional sample data SUBJECT_SAMPLE_FACTORS - 10_413255 Sample Type:Healthy Time Point=Dx; Osmolarity=286; MGIT (days)=-; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 101_450052 Sample Type:Recur Time Point=d7; Osmolarity=254; MGIT (days)=10; GeneXpert MTB/RIF Ct values=20.3; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 101_450281 Sample Type:Recur Time Point=w4; Osmolarity=291; MGIT (days)=12; GeneXpert MTB/RIF Ct values=16.9; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=1461.568; Comments=- SUBJECT_SAMPLE_FACTORS - 101_450624 Sample Type:Recur Time Point=w8; Osmolarity=253; MGIT (days)=16; GeneXpert MTB/RIF Ct values=21.2; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 101_455555 Sample Type:Recur Time Point=Dx; Osmolarity=267; MGIT (days)=4; GeneXpert MTB/RIF Ct values=16.2; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=1373.248; Comments=- SUBJECT_SAMPLE_FACTORS - 101_6015637 Sample Type:Recur Time Point=w24; Osmolarity=307; MGIT (days)=50; GeneXpert MTB/RIF Ct values=26.3; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=842.048; Comments=- SUBJECT_SAMPLE_FACTORS - 112_451057 Sample Type:Recur Time Point=Dx; Osmolarity=173; MGIT (days)=4; GeneXpert MTB/RIF Ct values=17.3; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=1836.7; Comments=- SUBJECT_SAMPLE_FACTORS - 112_451332 Sample Type:Recur Time Point=d7; Osmolarity=229; MGIT (days)=13; GeneXpert MTB/RIF Ct values=24.7; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 112_451762 Sample Type:Recur Time Point=w4; Osmolarity=225; MGIT (days)=21; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=1279.2; Comments=Error (GeneXpert) SUBJECT_SAMPLE_FACTORS - 112_6015022 Sample Type:Recur Time Point=w8; Osmolarity=212; MGIT (days)=50; GeneXpert MTB/RIF Ct values=31.3; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 112_6016968 Sample Type:Recur Time Point=w24; Osmolarity=162; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=684.9; Comments=- SUBJECT_SAMPLE_FACTORS - 130_6015094 Sample Type:Recur Time Point=Dx; Osmolarity=252; MGIT (days)=6; GeneXpert MTB/RIF Ct values=23.8; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=994.176; Comments=- SUBJECT_SAMPLE_FACTORS - 130_6015197 Sample Type:Recur Time Point=d7; Osmolarity=261; MGIT (days)=9; GeneXpert MTB/RIF Ct values=18.6; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 130_6015602 Sample Type:Recur Time Point=w4; Osmolarity=230; MGIT (days)=-; GeneXpert MTB/RIF Ct values=31.1; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=707.456; Comments=- SUBJECT_SAMPLE_FACTORS - 130_6016222 Sample Type:Recur Time Point=w8; Osmolarity=317; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 130_6018022 Sample Type:Recur Time Point=w24; Osmolarity=193; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=26.00192; Comments=- SUBJECT_SAMPLE_FACTORS - 133_6015125 Sample Type:Cure Time Point=Dx; Osmolarity=325; MGIT (days)=6; GeneXpert MTB/RIF Ct values=21; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=1632.96; Comments=- SUBJECT_SAMPLE_FACTORS - 133_6015265 Sample Type:Cure Time Point=d7; Osmolarity=278; MGIT (days)=9; GeneXpert MTB/RIF Ct values=21.7; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 133_6015609 Sample Type:Cure Time Point=w4; Osmolarity=299; MGIT (days)=12; GeneXpert MTB/RIF Ct values=13.6; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=1037.12; Comments=- SUBJECT_SAMPLE_FACTORS - 133_6017982 Sample Type:Cure Time Point=w24; Osmolarity=269; MGIT (days)=50; GeneXpert MTB/RIF Ct values=33.7; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=293.216; Comments=- SUBJECT_SAMPLE_FACTORS - 137_6015177 Sample Type:Recur Time Point=Dx; Osmolarity=273; MGIT (days)=7; GeneXpert MTB/RIF Ct values=24.4; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=2006.336; Comments=- SUBJECT_SAMPLE_FACTORS - 137_6015271 Sample Type:Recur Time Point=d7; Osmolarity=270; MGIT (days)=4; GeneXpert MTB/RIF Ct values=20.8; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 137_6015809 Sample Type:Recur Time Point=w4; Osmolarity=314; MGIT (days)=15; GeneXpert MTB/RIF Ct values=18.3; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=2096.512; Comments=- SUBJECT_SAMPLE_FACTORS - 137_6016220 Sample Type:Recur Time Point=w8; Osmolarity=158; MGIT (days)=50; GeneXpert MTB/RIF Ct values=26.7; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 137_6018150 Sample Type:Recur Time Point=w24; Osmolarity=247; MGIT (days)=50; GeneXpert MTB/RIF Ct values=30.2; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=405.9648; Comments=- SUBJECT_SAMPLE_FACTORS - 140_6015623 Sample Type:Recur Time Point=Dx; Osmolarity=399; MGIT (days)=6; GeneXpert MTB/RIF Ct values=19; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=1735.8; Comments=- SUBJECT_SAMPLE_FACTORS - 140_6015715 Sample Type:Recur Time Point=d7; Osmolarity=436; MGIT (days)=12; GeneXpert MTB/RIF Ct values=30.8; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 140_6016195 Sample Type:Recur Time Point=w4; Osmolarity=385; MGIT (days)=27; GeneXpert MTB/RIF Ct values=32.6; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=953.0; Comments=- SUBJECT_SAMPLE_FACTORS - 140_6016433 Sample Type:Recur Time Point=w8; Osmolarity=315; MGIT (days)=25; GeneXpert MTB/RIF Ct values=26; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 140_6018311 Sample Type:Recur Time Point=w24; Osmolarity=287; MGIT (days)=50; GeneXpert MTB/RIF Ct values=31.8; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=222.2; Comments=- SUBJECT_SAMPLE_FACTORS - 142_6015471 Sample Type:Recur Time Point=Dx; Osmolarity=180; MGIT (days)=3; GeneXpert MTB/RIF Ct values=15.3; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=1980.864; Comments=- SUBJECT_SAMPLE_FACTORS - 142_6015673 Sample Type:Recur Time Point=d7; Osmolarity=113; MGIT (days)=6; GeneXpert MTB/RIF Ct values=18; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 142_6016207 Sample Type:Recur Time Point=w4; Osmolarity=129; MGIT (days)=13; GeneXpert MTB/RIF Ct values=19.9; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=2019.584; Comments=- SUBJECT_SAMPLE_FACTORS - 142_6016435 Sample Type:Recur Time Point=w8; Osmolarity=210; MGIT (days)=25; GeneXpert MTB/RIF Ct values=18.8; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 142_6018238 Sample Type:Recur Time Point=w24; Osmolarity=53; MGIT (days)=50; GeneXpert MTB/RIF Ct values=32.3; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=922.176; Comments=- SUBJECT_SAMPLE_FACTORS - 144_6016655 Sample Type:Cure Time Point=Dx; Osmolarity=311; MGIT (days)=7; GeneXpert MTB/RIF Ct values=23.2; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=1578.368; Comments=- SUBJECT_SAMPLE_FACTORS - 144_6016764 Sample Type:Cure Time Point=d7; Osmolarity=357; MGIT (days)=7; GeneXpert MTB/RIF Ct values=19.2; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 144_6017147 Sample Type:Cure Time Point=w4; Osmolarity=311; MGIT (days)=3; GeneXpert MTB/RIF Ct values=23.6; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=1383.424; Comments=- SUBJECT_SAMPLE_FACTORS - 144_6017656 Sample Type:Cure Time Point=w8; Osmolarity=401; MGIT (days)=28; GeneXpert MTB/RIF Ct values=27.6; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 144_6019586 Sample Type:Cure Time Point=w24; Osmolarity=252; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=197.3824; Comments=- SUBJECT_SAMPLE_FACTORS - 152_6016782 Sample Type:Recur Time Point=Dx; Osmolarity=152; MGIT (days)=7; GeneXpert MTB/RIF Ct values=17.5; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=312.5184; Comments=- SUBJECT_SAMPLE_FACTORS - 152_6016992 Sample Type:Recur Time Point=d7; Osmolarity=270; MGIT (days)=13; GeneXpert MTB/RIF Ct values=21.2; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 152_6017317 Sample Type:Recur Time Point=w4; Osmolarity=185; MGIT (days)=29; GeneXpert MTB/RIF Ct values=28.7; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=227.0784; Comments=- SUBJECT_SAMPLE_FACTORS - 152_6017746 Sample Type:Recur Time Point=w8; Osmolarity=300; MGIT (days)=50; GeneXpert MTB/RIF Ct values=31.8; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 152_6019754 Sample Type:Recur Time Point=w24; Osmolarity=322; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=64.8896; Comments=- SUBJECT_SAMPLE_FACTORS - 163_6017331 Sample Type:Fail Time Point=Dx; Osmolarity=200; MGIT (days)=4; GeneXpert MTB/RIF Ct values=15.4; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=5985.6; Comments=- SUBJECT_SAMPLE_FACTORS - 163_6017429 Sample Type:Fail Time Point=d7; Osmolarity=223; MGIT (days)=8; GeneXpert MTB/RIF Ct values=13.5; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 163_6017645 Sample Type:Fail Time Point=w4; Osmolarity=282; MGIT (days)=15; GeneXpert MTB/RIF Ct values=18.9; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=4338.752; Comments=- SUBJECT_SAMPLE_FACTORS - 163_6018193 Sample Type:Fail Time Point=w8; Osmolarity=200; MGIT (days)=31; GeneXpert MTB/RIF Ct values=20.8; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 163_6020093 Sample Type:Fail Time Point=w24; Osmolarity=252; MGIT (days)=9; GeneXpert MTB/RIF Ct values=23; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=1324.16; Comments=- SUBJECT_SAMPLE_FACTORS - 168_6017455 Sample Type:Fail Time Point=Dx; Osmolarity=266; MGIT (days)=4; GeneXpert MTB/RIF Ct values=14.5; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=1986.176; Comments=- SUBJECT_SAMPLE_FACTORS - 168_6017632 Sample Type:Fail Time Point=d7; Osmolarity=217; MGIT (days)=7; GeneXpert MTB/RIF Ct values=13.7; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 168_6017995 Sample Type:Fail Time Point=w4; Osmolarity=130; MGIT (days)=50; GeneXpert MTB/RIF Ct values=15.1; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=1477.952; Comments=- SUBJECT_SAMPLE_FACTORS - 168_6018319 Sample Type:Fail Time Point=w8; Osmolarity=374; MGIT (days)=50; GeneXpert MTB/RIF Ct values=23.8; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 168_6020172 Sample Type:Fail Time Point=w24; Osmolarity=266; MGIT (days)=5; GeneXpert MTB/RIF Ct values=19.2; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=1039.936; Comments=- SUBJECT_SAMPLE_FACTORS - 169_6017465 Sample Type:Fail Time Point=Dx; Osmolarity=289; MGIT (days)=4; GeneXpert MTB/RIF Ct values=27.2; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=1564.736; Comments=- SUBJECT_SAMPLE_FACTORS - 169_6017639 Sample Type:Fail Time Point=d7; Osmolarity=275; MGIT (days)=24; GeneXpert MTB/RIF Ct values=21; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 169_6017991 Sample Type:Fail Time Point=w4; Osmolarity=304; MGIT (days)=50; GeneXpert MTB/RIF Ct values=24.1; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=2552.512; Comments=- SUBJECT_SAMPLE_FACTORS - 169_6018329 Sample Type:Fail Time Point=w8; Osmolarity=283; MGIT (days)=50; GeneXpert MTB/RIF Ct values=28.5; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 169_6020182 Sample Type:Fail Time Point=w24; Osmolarity=76; MGIT (days)=20; GeneXpert MTB/RIF Ct values=20.2; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=224.7552; Comments=- SUBJECT_SAMPLE_FACTORS - 19_413660 Sample Type:Fail Time Point=Dx; Osmolarity=136; MGIT (days)=5; GeneXpert MTB/RIF Ct values=16.1; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=5392.832; Comments=- SUBJECT_SAMPLE_FACTORS - 19_413693 Sample Type:Fail Time Point=d7; Osmolarity=118; MGIT (days)=12; GeneXpert MTB/RIF Ct values=26.2; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 19_414721 Sample Type:Fail Time Point=w4; Osmolarity=170; MGIT (days)=15; GeneXpert MTB/RIF Ct values=24.4; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=6528; Comments=- SUBJECT_SAMPLE_FACTORS - 19_415454 Sample Type:Fail Time Point=w8; Osmolarity=219; MGIT (days)=3; GeneXpert MTB/RIF Ct values=24.1; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=Contamination (MGIT) SUBJECT_SAMPLE_FACTORS - 19_416777 Sample Type:Fail Time Point=w24; Osmolarity=258; MGIT (days)=11; GeneXpert MTB/RIF Ct values=25.9; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=1174.528; Comments=- SUBJECT_SAMPLE_FACTORS - 21_413701 Sample Type:Fail Time Point=Dx; Osmolarity=218; MGIT (days)=4; GeneXpert MTB/RIF Ct values=17.5; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=4724.48; Comments=- SUBJECT_SAMPLE_FACTORS - 21_413955 Sample Type:Fail Time Point=d7; Osmolarity=279; MGIT (days)=8; GeneXpert MTB/RIF Ct values=24.1; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 21_414539 Sample Type:Fail Time Point=w4; Osmolarity=244; MGIT (days)=5; GeneXpert MTB/RIF Ct values=21; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=3859.328; Comments=- SUBJECT_SAMPLE_FACTORS - 21_415469 Sample Type:Fail Time Point=w8; Osmolarity=190; MGIT (days)=1; GeneXpert MTB/RIF Ct values=20.4; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=Contamination (MGIT) SUBJECT_SAMPLE_FACTORS - 21_417709 Sample Type:Fail Time Point=w24; Osmolarity=197; MGIT (days)=6; GeneXpert MTB/RIF Ct values=22.3; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=5271.232; Comments=- SUBJECT_SAMPLE_FACTORS - 22_414462 Sample Type:Recur Time Point=Dx; Osmolarity=193; MGIT (days)=7; GeneXpert MTB/RIF Ct values=26.6; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=528.8704; Comments=- SUBJECT_SAMPLE_FACTORS - 22_414616 Sample Type:Recur Time Point=d7; Osmolarity=234; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 22_415083 Sample Type:Recur Time Point=w4; Osmolarity=268; MGIT (days)=50; GeneXpert MTB/RIF Ct values=33; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=479.7248; Comments=- SUBJECT_SAMPLE_FACTORS - 22_415489 Sample Type:Recur Time Point=w8; Osmolarity=288; MGIT (days)=1; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=Contamination (MGIT) SUBJECT_SAMPLE_FACTORS - 22_417071 Sample Type:Recur Time Point=w24; Osmolarity=273; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=172.9344; Comments=- SUBJECT_SAMPLE_FACTORS - 27_414865 Sample Type:Fail Time Point=Dx; Osmolarity=209; MGIT (days)=4; GeneXpert MTB/RIF Ct values=14.5; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=5671.488; Comments=- SUBJECT_SAMPLE_FACTORS - 27_415062 Sample Type:Fail Time Point=d7; Osmolarity=220; MGIT (days)=8; GeneXpert MTB/RIF Ct values=19.3; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 27_415512 Sample Type:Fail Time Point=w4; Osmolarity=120; MGIT (days)=1; GeneXpert MTB/RIF Ct values=29.5; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=5581.248; Comments=Contamination (MGIT) SUBJECT_SAMPLE_FACTORS - 27_415768 Sample Type:Fail Time Point=w8; Osmolarity=249; MGIT (days)=11; GeneXpert MTB/RIF Ct values=30.4; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 27_417177 Sample Type:Fail Time Point=w24; Osmolarity=137; MGIT (days)=18; GeneXpert MTB/RIF Ct values=29.3; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=5601.728; Comments=- SUBJECT_SAMPLE_FACTORS - 3_412447 Sample Type:Fail Time Point=Dx; Osmolarity=292; MGIT (days)=4; GeneXpert MTB/RIF Ct values=15.7; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=2434.56; Comments=- SUBJECT_SAMPLE_FACTORS - 3_412477 Sample Type:Fail Time Point=d7; Osmolarity=217; MGIT (days)=6; GeneXpert MTB/RIF Ct values=17.3; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 3_413084 Sample Type:Fail Time Point=w4; Osmolarity=273; MGIT (days)=4; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=2353.408; Comments=Error (GeneXpert) SUBJECT_SAMPLE_FACTORS - 3_413494 Sample Type:Fail Time Point=w8; Osmolarity=218; MGIT (days)=4; GeneXpert MTB/RIF Ct values=16.9; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 3_415915 Sample Type:Fail Time Point=w24; Osmolarity=265; MGIT (days)=3; GeneXpert MTB/RIF Ct values=17.2; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=2883.456; Comments=- SUBJECT_SAMPLE_FACTORS - 34_415815 Sample Type:Recur Time Point=Dx; Osmolarity=224; MGIT (days)=9; GeneXpert MTB/RIF Ct values=27.2; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=1309.952; Comments=- SUBJECT_SAMPLE_FACTORS - 34_415963 Sample Type:Recur Time Point=d7; Osmolarity=267; MGIT (days)=16; GeneXpert MTB/RIF Ct values=27; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 34_416720 Sample Type:Recur Time Point=w8; Osmolarity=326; MGIT (days)=28; GeneXpert MTB/RIF Ct values=34.3; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 34_417623 Sample Type:Recur Time Point=w24; Osmolarity=101; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=134.3616; Comments=- SUBJECT_SAMPLE_FACTORS - 34_417920 Sample Type:Recur Time Point=w4; Osmolarity=304; MGIT (days)=50; GeneXpert MTB/RIF Ct values=30.4; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=298.752; Comments=- SUBJECT_SAMPLE_FACTORS - 36_417863 Sample Type:Healthy Time Point=Dx; Osmolarity=287; MGIT (days)=43; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=Contamination (MGIT) SUBJECT_SAMPLE_FACTORS - 38_417787 Sample Type:Healthy Time Point=Dx; Osmolarity=281; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 39_417770 Sample Type:Healthy Time Point=Dx; Osmolarity=341; MGIT (days)=7; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=Contamination (MGIT) SUBJECT_SAMPLE_FACTORS - 4_412467 Sample Type:Cure Time Point=Dx; Osmolarity=297; MGIT (days)=6; GeneXpert MTB/RIF Ct values=22.7; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=5863.936; Comments=- SUBJECT_SAMPLE_FACTORS - 4_412676 Sample Type:Cure Time Point=d7; Osmolarity=229; MGIT (days)=12; GeneXpert MTB/RIF Ct values=23.2; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 4_413165 Sample Type:Cure Time Point=w4; Osmolarity=246; MGIT (days)=16; GeneXpert MTB/RIF Ct values=26.2; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=2233.28; Comments=- SUBJECT_SAMPLE_FACTORS - 4_413529 Sample Type:Cure Time Point=w8; Osmolarity=243; MGIT (days)=50; GeneXpert MTB/RIF Ct values=30.8; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 4_415983 Sample Type:Cure Time Point=w24; Osmolarity=248; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=116.2048; Comments=- SUBJECT_SAMPLE_FACTORS - 41_416680 Sample Type:Cure Time Point=d7; Osmolarity=197; MGIT (days)=20; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 41_416839 Sample Type:Cure Time Point=w4; Osmolarity=339; MGIT (days)=16; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=167.4688; Comments=- SUBJECT_SAMPLE_FACTORS - 41_417796 Sample Type:Cure Time Point=Dx; Osmolarity=335; MGIT (days)=19; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=384.96; Comments=- SUBJECT_SAMPLE_FACTORS - 41_417812 Sample Type:Cure Time Point=w8; Osmolarity=244; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 41_452528 Sample Type:Cure Time Point=w24; Osmolarity=301; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=21.06048; Comments=- SUBJECT_SAMPLE_FACTORS - 42_416647 Sample Type:Cure Time Point=Dx; Osmolarity=152; MGIT (days)=4; GeneXpert MTB/RIF Ct values=18.7; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=1603.136; Comments=- SUBJECT_SAMPLE_FACTORS - 42_417082 Sample Type:Cure Time Point=w4; Osmolarity=195; MGIT (days)=7; GeneXpert MTB/RIF Ct values=15.8; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=753.472; Comments=- SUBJECT_SAMPLE_FACTORS - 42_417298 Sample Type:Cure Time Point=w8; Osmolarity=245; MGIT (days)=3; GeneXpert MTB/RIF Ct values=27.4; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 42_417730 Sample Type:Cure Time Point=d7; Osmolarity=197; MGIT (days)=50; GeneXpert MTB/RIF Ct values=29.7; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 42_452621 Sample Type:Cure Time Point=w24; Osmolarity=124; MGIT (days)=50; GeneXpert MTB/RIF Ct values=30.3; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=119.232; Comments=- SUBJECT_SAMPLE_FACTORS - 43_416684 Sample Type:Fail Time Point=Dx; Osmolarity=319; MGIT (days)=5; GeneXpert MTB/RIF Ct values=21.6; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=391.6736; Comments=- SUBJECT_SAMPLE_FACTORS - 43_416760 Sample Type:Fail Time Point=d7; Osmolarity=377; MGIT (days)=10; GeneXpert MTB/RIF Ct values=26.9; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 43_416824 Sample Type:Fail Time Point=w4; Osmolarity=332; MGIT (days)=18; GeneXpert MTB/RIF Ct values=27.5; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=286.1568; Comments=- SUBJECT_SAMPLE_FACTORS - 43_417332 Sample Type:Fail Time Point=w8; Osmolarity=343; MGIT (days)=22; GeneXpert MTB/RIF Ct values=27.8; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 43_452641 Sample Type:Fail Time Point=w24; Osmolarity=276; MGIT (days)=19; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=170.048; Comments=- SUBJECT_SAMPLE_FACTORS - 45_416796 Sample Type:Healthy Time Point=Dx; Osmolarity=224; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 48_452312 Sample Type:Healthy Time Point=Dx; Osmolarity=290; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 49_417104 Sample Type:Cure Time Point=Dx; Osmolarity=173; MGIT (days)=3; GeneXpert MTB/RIF Ct values=19.5; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=2400.192; Comments=- SUBJECT_SAMPLE_FACTORS - 49_417197 Sample Type:Cure Time Point=d7; Osmolarity=258; MGIT (days)=4; GeneXpert MTB/RIF Ct values=25.2; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=Contamination (MGIT) SUBJECT_SAMPLE_FACTORS - 49_417420 Sample Type:Cure Time Point=w4; Osmolarity=1103; MGIT (days)=14; GeneXpert MTB/RIF Ct values=28.6; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=2619.968; Comments=- SUBJECT_SAMPLE_FACTORS - 49_417599 Sample Type:Cure Time Point=w8; Osmolarity=232; MGIT (days)=50; GeneXpert MTB/RIF Ct values=31.1; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 49_452751 Sample Type:Cure Time Point=w24; Osmolarity=285; MGIT (days)=5; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=580.8576; Comments=Contamination (MGIT) SUBJECT_SAMPLE_FACTORS - 52_417241 Sample Type:Cure Time Point=Dx; Osmolarity=291; MGIT (days)=6; GeneXpert MTB/RIF Ct values=19.3; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=3267.136; Comments=- SUBJECT_SAMPLE_FACTORS - 52_417306 Sample Type:Cure Time Point=w4; Osmolarity=217; MGIT (days)=6; GeneXpert MTB/RIF Ct values=19.1; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=3187.52; Comments=- SUBJECT_SAMPLE_FACTORS - 52_417327 Sample Type:Cure Time Point=d7; Osmolarity=253; MGIT (days)=16; GeneXpert MTB/RIF Ct values=25.5; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 52_417612 Sample Type:Cure Time Point=w8; Osmolarity=199; MGIT (days)=50; GeneXpert MTB/RIF Ct values=29.8; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 52_453273 Sample Type:Cure Time Point=w24; Osmolarity=388; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=1291.52; Comments=- SUBJECT_SAMPLE_FACTORS - 53_417231 Sample Type:Cure Time Point=Dx; Osmolarity=243; MGIT (days)=4; GeneXpert MTB/RIF Ct values=15.7; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=10368; Comments=- SUBJECT_SAMPLE_FACTORS - 53_417276 Sample Type:Cure Time Point=d7; Osmolarity=305; MGIT (days)=9; GeneXpert MTB/RIF Ct values=20.5; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 53_417432 Sample Type:Cure Time Point=w4; Osmolarity=275; MGIT (days)=14; GeneXpert MTB/RIF Ct values=25.2; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=11968; Comments=- SUBJECT_SAMPLE_FACTORS - 53_452177 Sample Type:Cure Time Point=w8; Osmolarity=305; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 53_452557 Sample Type:Cure Time Point=w24; Osmolarity=314; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=553.0048; Comments=- SUBJECT_SAMPLE_FACTORS - 54_417397 Sample Type:Cure Time Point=Dx; Osmolarity=163; MGIT (days)=10; GeneXpert MTB/RIF Ct values=24.7; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=205.9776; Comments=- SUBJECT_SAMPLE_FACTORS - 54_417526 Sample Type:Cure Time Point=w4; Osmolarity=155; MGIT (days)=18; GeneXpert MTB/RIF Ct values=23.3; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=69.9712; Comments=- SUBJECT_SAMPLE_FACTORS - 54_417543 Sample Type:Cure Time Point=d7; Osmolarity=95; MGIT (days)=29; GeneXpert MTB/RIF Ct values=27.8; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 54_452300 Sample Type:Cure Time Point=w8; Osmolarity=130; MGIT (days)=8; GeneXpert MTB/RIF Ct values=31; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=Contamination (MGIT) SUBJECT_SAMPLE_FACTORS - 54_453981 Sample Type:Cure Time Point=w24; Osmolarity=88; MGIT (days)=50; GeneXpert MTB/RIF Ct values=29.3; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=123.7632; Comments=- SUBJECT_SAMPLE_FACTORS - 57_452199 Sample Type:Healthy Time Point=Dx; Osmolarity=231; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 6_412774 Sample Type:Healthy Time Point=Dx; Osmolarity=184; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 60_452228 Sample Type:Healthy Time Point=Dx; Osmolarity=154; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 62_452365 Sample Type:Healthy Time Point=Dx; Osmolarity=276; MGIT (days)=9; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=Contamination (MGIT) SUBJECT_SAMPLE_FACTORS - 63_452409 Sample Type:Healthy Time Point=Dx; Osmolarity=189; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 65_452417 Sample Type:Healthy Time Point=Dx; Osmolarity=288; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 67_452529 Sample Type:Healthy Time Point=Dx; Osmolarity=150; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 68_452463 Sample Type:Healthy Time Point=Dx; Osmolarity=312; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 70_452497 Sample Type:Cure Time Point=Dx; Osmolarity=260; MGIT (days)=4; GeneXpert MTB/RIF Ct values=19.5; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=2225.152; Comments=- SUBJECT_SAMPLE_FACTORS - 70_452598 Sample Type:Cure Time Point=d7; Osmolarity=209; MGIT (days)=9; GeneXpert MTB/RIF Ct values=18.6; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 70_452879 Sample Type:Cure Time Point=w4; Osmolarity=281; MGIT (days)=11; GeneXpert MTB/RIF Ct values=21.5; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=1851.648; Comments=- SUBJECT_SAMPLE_FACTORS - 70_453399 Sample Type:Cure Time Point=w8; Osmolarity=241; MGIT (days)=9; GeneXpert MTB/RIF Ct values=23.7; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 70_454358 Sample Type:Cure Time Point=w24; Osmolarity=335; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=526.9952; Comments=- SUBJECT_SAMPLE_FACTORS - 72_452579 Sample Type:Cure Time Point=Dx; Osmolarity=198; MGIT (days)=3; GeneXpert MTB/RIF Ct values=17.4; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=2463.744; Comments=- SUBJECT_SAMPLE_FACTORS - 72_452697 Sample Type:Cure Time Point=d7; Osmolarity=103; MGIT (days)=6; GeneXpert MTB/RIF Ct values=14.8; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=Contamination (MGIT) SUBJECT_SAMPLE_FACTORS - 72_452708 Sample Type:Cure Time Point=w4; Osmolarity=150; MGIT (days)=19; GeneXpert MTB/RIF Ct values=27.2; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=2202.624; Comments=- SUBJECT_SAMPLE_FACTORS - 72_453409 Sample Type:Cure Time Point=w8; Osmolarity=564; MGIT (days)=8; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 72_454467 Sample Type:Cure Time Point=w24; Osmolarity=123; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=360.6848; Comments=- SUBJECT_SAMPLE_FACTORS - 76_452740 Sample Type:Cure Time Point=d7; Osmolarity=286; MGIT (days)=10; GeneXpert MTB/RIF Ct values=26.9; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 76_453251 Sample Type:Cure Time Point=Dx; Osmolarity=278; MGIT (days)=7; GeneXpert MTB/RIF Ct values=27.6; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=8384; Comments=- SUBJECT_SAMPLE_FACTORS - 76_453628 Sample Type:Cure Time Point=w4; Osmolarity=571; MGIT (days)=11; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=8576; Comments=Error (GeneXpert) SUBJECT_SAMPLE_FACTORS - 76_453992 Sample Type:Cure Time Point=w8; Osmolarity=460; MGIT (days)=50; GeneXpert MTB/RIF Ct values=23.9; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 76_454831 Sample Type:Cure Time Point=w24; Osmolarity=598; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=832.32; Comments=- SUBJECT_SAMPLE_FACTORS - 77_453178 Sample Type:Cure Time Point=Dx; Osmolarity=226; MGIT (days)=5; GeneXpert MTB/RIF Ct values=19.6; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=3226.368; Comments=- SUBJECT_SAMPLE_FACTORS - 77_453331 Sample Type:Cure Time Point=d7; Osmolarity=136; MGIT (days)=10; GeneXpert MTB/RIF Ct values=22.5; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=Contamination (MGIT) SUBJECT_SAMPLE_FACTORS - 77_453575 Sample Type:Cure Time Point=w4; Osmolarity=414; MGIT (days)=14; GeneXpert MTB/RIF Ct values=30; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=1283.84; Comments=- SUBJECT_SAMPLE_FACTORS - 77_453869 Sample Type:Cure Time Point=w8; Osmolarity=32; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 77_454840 Sample Type:Cure Time Point=w24; Osmolarity=318; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=214.5152; Comments=- SUBJECT_SAMPLE_FACTORS - 84_450359 Sample Type:Cure Time Point=w24; Osmolarity=263; MGIT (days)=50; GeneXpert MTB/RIF Ct values=32.4; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=1100.672; Comments=- SUBJECT_SAMPLE_FACTORS - 84_454074 Sample Type:Cure Time Point=Dx; Osmolarity=334; MGIT (days)=4; GeneXpert MTB/RIF Ct values=17.1; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=5798.144; Comments=- SUBJECT_SAMPLE_FACTORS - 84_454302 Sample Type:Cure Time Point=d7; Osmolarity=293; MGIT (days)=8; GeneXpert MTB/RIF Ct values=20.4; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 84_454456 Sample Type:Cure Time Point=w4; Osmolarity=270; MGIT (days)=17; GeneXpert MTB/RIF Ct values=22.9; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=3977.792; Comments=- SUBJECT_SAMPLE_FACTORS - 84_454731 Sample Type:Cure Time Point=w8; Osmolarity=291; MGIT (days)=50; GeneXpert MTB/RIF Ct values=33.2; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 88_451006 Sample Type:Recur Time Point=w24; Osmolarity=318; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=376.8512; Comments=- SUBJECT_SAMPLE_FACTORS - 88_454578 Sample Type:Recur Time Point=Dx; Osmolarity=254; MGIT (days)=12; GeneXpert MTB/RIF Ct values=31.6; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=963.584; Comments=- SUBJECT_SAMPLE_FACTORS - 88_454619 Sample Type:Recur Time Point=d7; Osmolarity=248; MGIT (days)=15; GeneXpert MTB/RIF Ct values=29.7; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 88_454803 Sample Type:Recur Time Point=w4; Osmolarity=276; MGIT (days)=21; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=1275.328; Comments=- SUBJECT_SAMPLE_FACTORS - 88_455254 Sample Type:Recur Time Point=w8; Osmolarity=249; MGIT (days)=50; GeneXpert MTB/RIF Ct values=31.7; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 9_413017 Sample Type:Cure Time Point=Dx; Osmolarity=344; MGIT (days)=5; GeneXpert MTB/RIF Ct values=22.2; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=2981.952; Comments=- SUBJECT_SAMPLE_FACTORS - 9_413209 Sample Type:Cure Time Point=d7; Osmolarity=341; MGIT (days)=5; GeneXpert MTB/RIF Ct values=23.1; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 9_413423 Sample Type:Cure Time Point=w4; Osmolarity=305; MGIT (days)=9; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=1996.032; Comments=- SUBJECT_SAMPLE_FACTORS - 9_414448 Sample Type:Cure Time Point=w8; Osmolarity=207; MGIT (days)=23; GeneXpert MTB/RIF Ct values=34; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 9_416315 Sample Type:Cure Time Point=w24; Osmolarity=311; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=169.9776; Comments=- SUBJECT_SAMPLE_FACTORS - 93_450104 Sample Type:Recur Time Point=w8; Osmolarity=252; MGIT (days)=2; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 93_451939 Sample Type:Recur Time Point=w24; Osmolarity=52; MGIT (days)=3; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=34.95296; Comments=- SUBJECT_SAMPLE_FACTORS - 93_455155 Sample Type:Recur Time Point=Dx; Osmolarity=260; MGIT (days)=20; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=134.7776; Comments=- SUBJECT_SAMPLE_FACTORS - 93_455291 Sample Type:Recur Time Point=d7; Osmolarity=126; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 93_455371 Sample Type:Recur Time Point=w4; Osmolarity=222; MGIT (days)=27; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=80.1152; Comments=- SUBJECT_SAMPLE_FACTORS - 95_450006 Sample Type:Recur Time Point=w8; Osmolarity=300; MGIT (days)=19; GeneXpert MTB/RIF Ct values=27.2; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 95_451797 Sample Type:Recur Time Point=w24; Osmolarity=259; MGIT (days)=50; GeneXpert MTB/RIF Ct values=26.5; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=1446.656; Comments=- SUBJECT_SAMPLE_FACTORS - 95_454934 Sample Type:Recur Time Point=Dx; Osmolarity=318; MGIT (days)=3; GeneXpert MTB/RIF Ct values=21.3; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=5510.208; Comments=- SUBJECT_SAMPLE_FACTORS - 95_455274 Sample Type:Recur Time Point=d7; Osmolarity=171; MGIT (days)=8; GeneXpert MTB/RIF Ct values=18.3; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 95_455355 Sample Type:Recur Time Point=w4; Osmolarity=347; MGIT (days)=10; GeneXpert MTB/RIF Ct values=19.7; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=4489.92; Comments=- SUBJECT_SAMPLE_FACTORS - 99_450109 Sample Type:Cure Time Point=w4; Osmolarity=196; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=251.5648; Comments=- SUBJECT_SAMPLE_FACTORS - 99_450530 Sample Type:Cure Time Point=w8; Osmolarity=296; MGIT (days)=8; GeneXpert MTB/RIF Ct values=22; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 99_455509 Sample Type:Cure Time Point=Dx; Osmolarity=145; MGIT (days)=13; GeneXpert MTB/RIF Ct values=22.2; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=599.1872; Comments=- SUBJECT_SAMPLE_FACTORS - 99_455537 Sample Type:Cure Time Point=d7; Osmolarity=61; MGIT (days)=10; GeneXpert MTB/RIF Ct values=21.6; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 99_6016048 Sample Type:Cure Time Point=w24; Osmolarity=199; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=31.46048; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS16661 Sample Type:INDEX Time Point=-; Osmolarity=48; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS16663 Sample Type:TST- Time Point=-; Osmolarity=77; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS16675 Sample Type:TST- Time Point=-; Osmolarity=69; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS16682 Sample Type:INDEX Time Point=-; Osmolarity=68; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS16713 Sample Type:INDEX Time Point=-; Osmolarity=34; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS16714 Sample Type:TST+ Time Point=-; Osmolarity=35; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS16725 Sample Type:TST- Time Point=-; Osmolarity=66; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS16726 Sample Type:TST+ Time Point=-; Osmolarity=75; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS16841 Sample Type:INDEX Time Point=-; Osmolarity=34; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS16843 Sample Type:TST- Time Point=-; Osmolarity=155; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS16844 Sample Type:TST- Time Point=-; Osmolarity=93; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS16861 Sample Type:INDEX Time Point=-; Osmolarity=38; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS16862 Sample Type:TST+ Time Point=-; Osmolarity=81; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS16863 Sample Type:TST+ Time Point=-; Osmolarity=61; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS16868 Sample Type:INDEX Time Point=-; Osmolarity=76; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS16869 Sample Type:TST- Time Point=-; Osmolarity=47; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS16870 Sample Type:TST- Time Point=-; Osmolarity=88; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS16876 Sample Type:TST+ Time Point=-; Osmolarity=82; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS16877 Sample Type:TST- Time Point=-; Osmolarity=119; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS16878 Sample Type:TST+ Time Point=-; Osmolarity=94; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS16879 Sample Type:TST+ Time Point=-; Osmolarity=113; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS16884 Sample Type:INDEX Time Point=-; Osmolarity=96; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS16885 Sample Type:TST+ Time Point=-; Osmolarity=44; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS16924 Sample Type:TST- Time Point=-; Osmolarity=83; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS16925 Sample Type:TST- Time Point=-; Osmolarity=83; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS16926 Sample Type:TST- Time Point=-; Osmolarity=143; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS16951 Sample Type:INDEX Time Point=-; Osmolarity=47; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS16952 Sample Type:TST+ Time Point=-; Osmolarity=154; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS16955 Sample Type:TST- Time Point=-; Osmolarity=144; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS17012 Sample Type:INDEX Time Point=-; Osmolarity=33; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS17013 Sample Type:TST- Time Point=-; Osmolarity=59; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS17014 Sample Type:TST+ Time Point=-; Osmolarity=26; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS17027 Sample Type:INDEX Time Point=-; Osmolarity=36; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS17028 Sample Type:TST- Time Point=-; Osmolarity=141; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS17029 Sample Type:TST+ Time Point=-; Osmolarity=90; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS17030 Sample Type:TST+ Time Point=-; Osmolarity=120; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- #COLLECTION CO:COLLECTION_SUMMARY Urine was collected and frozen at -20 for storage. Prior to analysis, urine was CO:COLLECTION_SUMMARY thawed and centrifuged to remove particulates. CO:SAMPLE_TYPE Urine #TREATMENT TR:TREATMENT_SUMMARY Urine was analyzed by LC-MS #SAMPLEPREP SP:SAMPLEPREP_SUMMARY Urine was thawed on ice and centrifuged to remove particulates prior to SP:SAMPLEPREP_SUMMARY analysis. #CHROMATOGRAPHY CH:CHROMATOGRAPHY_TYPE Reversed phase CH:INSTRUMENT_NAME Agilent 1200 CH:COLUMN_NAME Atlantis T3 reverse-phase C18 3.5µm column (2.1 by 150mm CH:FLOW_GRADIENT 100% Solvent A to 90% Solvent B CH:FLOW_RATE 0.25 ml/min CH:COLUMN_TEMPERATURE 30 CH:SOLVENT_A 0.1% Formic Acid in Water CH:SOLVENT_B 0.1% Formic Acid in Methanol #ANALYSIS AN:ANALYSIS_TYPE MS AN:ANALYSIS_PROTOCOL_FILE SLC1G_Methods AN:DATA_FORMAT .d #MS MS:MS_COMMENTS - MS:INSTRUMENT_NAME Agilent 6230 TOF MS:INSTRUMENT_TYPE TOF MS:MS_TYPE ESI MS:ION_MODE POSITIVE MS:CAPILLARY_VOLTAGE 2000 V MS:DRY_GAS_FLOW 11 L/min MS:FRAGMENT_VOLTAGE 120 V MS:NEBULIZER 40 psi MS:OCTPOLE_VOLTAGE 750 V MS:SKIMMER_VOLTAGE 60 V #MS_METABOLITE_DATA MS_METABOLITE_DATA:UNITS counts MS_METABOLITE_DATA_START Samples KCHS16661 KCHS16661 KCHS16661 KCHS16663 KCHS16663 KCHS16663 KCHS16675 KCHS16675 KCHS16675 KCHS16682 KCHS16682 KCHS16682 KCHS16713 KCHS16713 KCHS16713 KCHS16714 KCHS16714 KCHS16714 KCHS16725 KCHS16725 KCHS16725 KCHS16726 KCHS16726 KCHS16726 KCHS16841 KCHS16841 KCHS16841 KCHS16843 KCHS16843 KCHS16843 KCHS16844 KCHS16844 KCHS16844 KCHS16861 KCHS16861 KCHS16861 KCHS16862 KCHS16862 KCHS16862 KCHS16863 KCHS16863 KCHS16863 KCHS16868 KCHS16868 KCHS16868 KCHS16869 KCHS16869 KCHS16869 KCHS16870 KCHS16870 KCHS16870 KCHS16876 KCHS16876 KCHS16876 KCHS16877 KCHS16877 KCHS16877 KCHS16878 KCHS16878 KCHS16878 KCHS16879 KCHS16879 KCHS16879 KCHS16884 KCHS16884 KCHS16885 KCHS16885 KCHS16885 KCHS16924 KCHS16924 KCHS16924 KCHS16925 KCHS16925 KCHS16925 KCHS16926 KCHS16926 KCHS16926 KCHS16951 KCHS16951 KCHS16951 KCHS16952 KCHS16952 KCHS16952 KCHS16955 KCHS16955 KCHS16955 KCHS17012 KCHS17012 KCHS17012 KCHS17013 KCHS17013 KCHS17013 KCHS17014 KCHS17014 KCHS17014 KCHS17027 KCHS17027 KCHS17027 KCHS17028 KCHS17028 KCHS17028 KCHS17029 KCHS17029 KCHS17029 KCHS17030 KCHS17030 KCHS17030 Factors Sample Type:INDEX Sample Type:INDEX Sample Type:INDEX Sample Type:TST- Sample Type:TST- Sample Type:TST- Sample Type:TST- Sample Type:TST- Sample Type:TST- Sample Type:INDEX Sample Type:INDEX Sample Type:INDEX Sample Type:INDEX Sample Type:INDEX Sample Type:INDEX Sample Type:TST+ Sample Type:TST+ Sample Type:TST+ Sample Type:TST- Sample Type:TST- Sample Type:TST- Sample Type:TST+ Sample Type:TST+ Sample Type:TST+ Sample Type:INDEX Sample Type:INDEX Sample Type:INDEX Sample Type:TST- Sample Type:TST- Sample Type:TST- Sample Type:TST- Sample Type:TST- Sample Type:TST- Sample Type:INDEX Sample Type:INDEX Sample Type:INDEX Sample Type:TST+ Sample Type:TST+ Sample Type:TST+ Sample Type:TST+ Sample Type:TST+ Sample Type:TST+ Sample Type:INDEX Sample Type:INDEX Sample Type:INDEX Sample Type:TST- Sample Type:TST- Sample Type:TST- Sample Type:TST- Sample Type:TST- Sample Type:TST- Sample Type:TST+ Sample Type:TST+ Sample Type:TST+ Sample Type:TST- Sample Type:TST- Sample Type:TST- Sample Type:TST+ Sample Type:TST+ Sample Type:TST+ Sample Type:TST+ Sample Type:TST+ Sample Type:TST+ Sample Type:INDEX Sample Type:INDEX Sample Type:TST+ Sample Type:TST+ Sample Type:TST+ Sample Type:TST- Sample Type:TST- Sample Type:TST- Sample Type:TST- Sample Type:TST- Sample Type:TST- Sample Type:TST- Sample Type:TST- Sample Type:TST- Sample Type:INDEX Sample Type:INDEX Sample Type:INDEX Sample Type:TST+ Sample Type:TST+ Sample Type:TST+ Sample Type:TST- Sample Type:TST- Sample Type:TST- Sample Type:INDEX Sample Type:INDEX Sample Type:INDEX Sample Type:TST- Sample Type:TST- Sample Type:TST- Sample Type:TST+ Sample Type:TST+ Sample Type:TST+ Sample Type:INDEX Sample Type:INDEX Sample Type:INDEX Sample Type:TST- Sample Type:TST- Sample Type:TST- Sample Type:TST+ Sample Type:TST+ Sample Type:TST+ Sample Type:TST+ Sample Type:TST+ Sample Type:TST+ SLC1G 41218.17634 41587.42895 43484.88464 14978.04857 15435.79157 17896.89933 11715.46769 14996.37767 15507.37719 33569.92115 34299.51765 34181.21162 554470.9951 571283.5754 614342.6215 106521.558 111839.2896 114515.0811 5640.062435 6986.736755 7790.168017 22035.76427 21313.58779 21796.42627 89276.05221 97998.79554 103241.4555 15133.2809 16787.08604 15780.90466 7593.879597 9017.68658 8421.308059 373347.7353 370185.0672 400264.8026 22826.75034 28726.27418 29480.6651 129778.0955 123478.2735 127690.0108 71595.07443 77204.22457 73622.26105 47247.51821 53915.74666 55555.85755 90417.51134 90449.36556 88107.54207 68849.79541 73241.76831 62406.59371 77095.02856 83571.50173 88120.22065 90193.22429 90314.52779 60615.78013 63289.96622 59861.56821 70126.12343 68792.95948 45774.70267 47811.92718 49613.25816 49831.11118 54155.05201 51150.71709 62216.87337 63423.61398 59733.2987 18160.56151 19543.71435 19244.56319 245818.0331 249813.0521 263956.9571 5805.998281 6322.310645 6594.796019 4101.386809 4081.460419 4623.50375 221556.1351 242905.3751 260460.8779 28899.95899 29153.33047 30672.05861 48843.73705 47020.16563 43802.73786 23624.7086 27456.63445 30841.20683 6359.733312 6769.151831 6465.369949 25352.71862 27449.50206 27362.17699 9545.074659 9106.001337 9624.294887 MS_METABOLITE_DATA_END #METABOLITES METABOLITES_START metabolite_name retention time m/z SLC1G 23.9 875.36 METABOLITES_END #END