#METABOLOMICS WORKBENCH blfitz_20181007_152720_mwtab.txt DATATRACK_ID:1529 STUDY_ID:ST001069 ANALYSIS_ID:AN001751 PROJECT_ID:PR000716 VERSION 1 CREATED_ON October 9, 2018, 6:20 pm #PROJECT PR:PROJECT_TITLE Evaluation of TB Treatment Response Biomarkers PR:PROJECT_TYPE Directed MS analysis PR:PROJECT_SUMMARY Directed MS analysis of promising treatment response biomarkers in TB patient PR:PROJECT_SUMMARY urine. PR:INSTITUTE Colorado State University PR:DEPARTMENT MIP PR:LABORATORY Belisle PR:LAST_NAME Fitzgerald PR:FIRST_NAME Bryna PR:ADDRESS 3185 Rampart Rd, Fort Collins, CO, 80521, USA PR:EMAIL blfitz@colostate.edu PR:PHONE 9704918905 PR:FUNDING_SOURCE NIH U01 AI-115619 #STUDY ST:STUDY_TITLE Evaluation of Seryl-leucine core 1 O-glycosylated peptide (SLC1G) in TB patient ST:STUDY_TITLE urine ST:STUDY_SUMMARY Previous work detected an uncharacterized urine metabolite with a molecular mass ST:STUDY_SUMMARY of 874.3547 Da that showed promise as a biomarker for successful TB treatment. ST:STUDY_SUMMARY Using mass spectrometry combined with enzymatic digestions, the metabolite was ST:STUDY_SUMMARY structurally characterized as a seryl-leucine core 1 O-glycosylated peptide ST:STUDY_SUMMARY (SLC1G) of human origin. Examination of SLC1G in urine revealed a significant ST:STUDY_SUMMARY abundance increase in individuals with active TB versus their household contacts ST:STUDY_SUMMARY and healthy controls. Moreover, differential decreases in SLC1G levels were ST:STUDY_SUMMARY observed by week-one in TB patients during successful treatment versus those ST:STUDY_SUMMARY that failed treatment. The SLC1G levels also associated with clinical parameters ST:STUDY_SUMMARY used to measure bacterial burden (GeneXpert) and inflammation (PET-CT). These ST:STUDY_SUMMARY results demonstrate the importance of metabolite identification and provide ST:STUDY_SUMMARY strong evidence for applying SLC1G as a biomarker of TB treatment response. ST:INSTITUTE Colorado State University ST:LAST_NAME Fitzgerald ST:FIRST_NAME Bryna ST:ADDRESS 3185 Rampart Rd ST:EMAIL blfitz@colostate.edu ST:PHONE 9704918905 #SUBJECT SU:SUBJECT_TYPE Human SU:SUBJECT_SPECIES Homo sapiens SU:TAXONOMY_ID 9606 #SUBJECT_SAMPLE_FACTORS: SUBJECT(optional)[tab]SAMPLE[tab]FACTORS(NAME:VALUE pairs separated by |)[tab]Additional sample data SUBJECT_SAMPLE_FACTORS - 10_413255 Sample Type:Healthy Time Point=Dx; Osmolarity=286; MGIT (days)=-; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 101_450052 Sample Type:Recur Time Point=d7; Osmolarity=254; MGIT (days)=10; GeneXpert MTB/RIF Ct values=20.3; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 101_450281 Sample Type:Recur Time Point=w4; Osmolarity=291; MGIT (days)=12; GeneXpert MTB/RIF Ct values=16.9; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=1461.568; Comments=- SUBJECT_SAMPLE_FACTORS - 101_450624 Sample Type:Recur Time Point=w8; Osmolarity=253; MGIT (days)=16; GeneXpert MTB/RIF Ct values=21.2; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 101_455555 Sample Type:Recur Time Point=Dx; Osmolarity=267; MGIT (days)=4; GeneXpert MTB/RIF Ct values=16.2; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=1373.248; Comments=- SUBJECT_SAMPLE_FACTORS - 101_6015637 Sample Type:Recur Time Point=w24; Osmolarity=307; MGIT (days)=50; GeneXpert MTB/RIF Ct values=26.3; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=842.048; Comments=- SUBJECT_SAMPLE_FACTORS - 112_451057 Sample Type:Recur Time Point=Dx; Osmolarity=173; MGIT (days)=4; GeneXpert MTB/RIF Ct values=17.3; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=1836.7; Comments=- SUBJECT_SAMPLE_FACTORS - 112_451332 Sample Type:Recur Time Point=d7; Osmolarity=229; MGIT (days)=13; GeneXpert MTB/RIF Ct values=24.7; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 112_451762 Sample Type:Recur Time Point=w4; Osmolarity=225; MGIT (days)=21; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=1279.2; Comments=Error (GeneXpert) SUBJECT_SAMPLE_FACTORS - 112_6015022 Sample Type:Recur Time Point=w8; Osmolarity=212; MGIT (days)=50; GeneXpert MTB/RIF Ct values=31.3; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 112_6016968 Sample Type:Recur Time Point=w24; Osmolarity=162; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=684.9; Comments=- SUBJECT_SAMPLE_FACTORS - 130_6015094 Sample Type:Recur Time Point=Dx; Osmolarity=252; MGIT (days)=6; GeneXpert MTB/RIF Ct values=23.8; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=994.176; Comments=- SUBJECT_SAMPLE_FACTORS - 130_6015197 Sample Type:Recur Time Point=d7; Osmolarity=261; MGIT (days)=9; GeneXpert MTB/RIF Ct values=18.6; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 130_6015602 Sample Type:Recur Time Point=w4; Osmolarity=230; MGIT (days)=-; GeneXpert MTB/RIF Ct values=31.1; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=707.456; Comments=- SUBJECT_SAMPLE_FACTORS - 130_6016222 Sample Type:Recur Time Point=w8; Osmolarity=317; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 130_6018022 Sample Type:Recur Time Point=w24; Osmolarity=193; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=26.00192; Comments=- SUBJECT_SAMPLE_FACTORS - 133_6015125 Sample Type:Cure Time Point=Dx; Osmolarity=325; MGIT (days)=6; GeneXpert MTB/RIF Ct values=21; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=1632.96; Comments=- SUBJECT_SAMPLE_FACTORS - 133_6015265 Sample Type:Cure Time Point=d7; Osmolarity=278; MGIT (days)=9; GeneXpert MTB/RIF Ct values=21.7; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 133_6015609 Sample Type:Cure Time Point=w4; Osmolarity=299; MGIT (days)=12; GeneXpert MTB/RIF Ct values=13.6; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=1037.12; Comments=- SUBJECT_SAMPLE_FACTORS - 133_6017982 Sample Type:Cure Time Point=w24; Osmolarity=269; MGIT (days)=50; GeneXpert MTB/RIF Ct values=33.7; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=293.216; Comments=- SUBJECT_SAMPLE_FACTORS - 137_6015177 Sample Type:Recur Time Point=Dx; Osmolarity=273; MGIT (days)=7; GeneXpert MTB/RIF Ct values=24.4; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=2006.336; Comments=- SUBJECT_SAMPLE_FACTORS - 137_6015271 Sample Type:Recur Time Point=d7; Osmolarity=270; MGIT (days)=4; GeneXpert MTB/RIF Ct values=20.8; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 137_6015809 Sample Type:Recur Time Point=w4; Osmolarity=314; MGIT (days)=15; GeneXpert MTB/RIF Ct values=18.3; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=2096.512; Comments=- SUBJECT_SAMPLE_FACTORS - 137_6016220 Sample Type:Recur Time Point=w8; Osmolarity=158; MGIT (days)=50; GeneXpert MTB/RIF Ct values=26.7; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 137_6018150 Sample Type:Recur Time Point=w24; Osmolarity=247; MGIT (days)=50; GeneXpert MTB/RIF Ct values=30.2; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=405.9648; Comments=- SUBJECT_SAMPLE_FACTORS - 140_6015623 Sample Type:Recur Time Point=Dx; Osmolarity=399; MGIT (days)=6; GeneXpert MTB/RIF Ct values=19; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=1735.8; Comments=- SUBJECT_SAMPLE_FACTORS - 140_6015715 Sample Type:Recur Time Point=d7; Osmolarity=436; MGIT (days)=12; GeneXpert MTB/RIF Ct values=30.8; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 140_6016195 Sample Type:Recur Time Point=w4; Osmolarity=385; MGIT (days)=27; GeneXpert MTB/RIF Ct values=32.6; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=953.0; Comments=- SUBJECT_SAMPLE_FACTORS - 140_6016433 Sample Type:Recur Time Point=w8; Osmolarity=315; MGIT (days)=25; GeneXpert MTB/RIF Ct values=26; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 140_6018311 Sample Type:Recur Time Point=w24; Osmolarity=287; MGIT (days)=50; GeneXpert MTB/RIF Ct values=31.8; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=222.2; Comments=- SUBJECT_SAMPLE_FACTORS - 142_6015471 Sample Type:Recur Time Point=Dx; Osmolarity=180; MGIT (days)=3; GeneXpert MTB/RIF Ct values=15.3; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=1980.864; Comments=- SUBJECT_SAMPLE_FACTORS - 142_6015673 Sample Type:Recur Time Point=d7; Osmolarity=113; MGIT (days)=6; GeneXpert MTB/RIF Ct values=18; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 142_6016207 Sample Type:Recur Time Point=w4; Osmolarity=129; MGIT (days)=13; GeneXpert MTB/RIF Ct values=19.9; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=2019.584; Comments=- SUBJECT_SAMPLE_FACTORS - 142_6016435 Sample Type:Recur Time Point=w8; Osmolarity=210; MGIT (days)=25; GeneXpert MTB/RIF Ct values=18.8; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 142_6018238 Sample Type:Recur Time Point=w24; Osmolarity=53; MGIT (days)=50; GeneXpert MTB/RIF Ct values=32.3; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=922.176; Comments=- SUBJECT_SAMPLE_FACTORS - 144_6016655 Sample Type:Cure Time Point=Dx; Osmolarity=311; MGIT (days)=7; GeneXpert MTB/RIF Ct values=23.2; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=1578.368; Comments=- SUBJECT_SAMPLE_FACTORS - 144_6016764 Sample Type:Cure Time Point=d7; Osmolarity=357; MGIT (days)=7; GeneXpert MTB/RIF Ct values=19.2; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 144_6017147 Sample Type:Cure Time Point=w4; Osmolarity=311; MGIT (days)=3; GeneXpert MTB/RIF Ct values=23.6; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=1383.424; Comments=- SUBJECT_SAMPLE_FACTORS - 144_6017656 Sample Type:Cure Time Point=w8; Osmolarity=401; MGIT (days)=28; GeneXpert MTB/RIF Ct values=27.6; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 144_6019586 Sample Type:Cure Time Point=w24; Osmolarity=252; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=197.3824; Comments=- SUBJECT_SAMPLE_FACTORS - 152_6016782 Sample Type:Recur Time Point=Dx; Osmolarity=152; MGIT (days)=7; GeneXpert MTB/RIF Ct values=17.5; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=312.5184; Comments=- SUBJECT_SAMPLE_FACTORS - 152_6016992 Sample Type:Recur Time Point=d7; Osmolarity=270; MGIT (days)=13; GeneXpert MTB/RIF Ct values=21.2; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 152_6017317 Sample Type:Recur Time Point=w4; Osmolarity=185; MGIT (days)=29; GeneXpert MTB/RIF Ct values=28.7; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=227.0784; Comments=- SUBJECT_SAMPLE_FACTORS - 152_6017746 Sample Type:Recur Time Point=w8; Osmolarity=300; MGIT (days)=50; GeneXpert MTB/RIF Ct values=31.8; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 152_6019754 Sample Type:Recur Time Point=w24; Osmolarity=322; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=64.8896; Comments=- SUBJECT_SAMPLE_FACTORS - 163_6017331 Sample Type:Fail Time Point=Dx; Osmolarity=200; MGIT (days)=4; GeneXpert MTB/RIF Ct values=15.4; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=5985.6; Comments=- SUBJECT_SAMPLE_FACTORS - 163_6017429 Sample Type:Fail Time Point=d7; Osmolarity=223; MGIT (days)=8; GeneXpert MTB/RIF Ct values=13.5; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 163_6017645 Sample Type:Fail Time Point=w4; Osmolarity=282; MGIT (days)=15; GeneXpert MTB/RIF Ct values=18.9; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=4338.752; Comments=- SUBJECT_SAMPLE_FACTORS - 163_6018193 Sample Type:Fail Time Point=w8; Osmolarity=200; MGIT (days)=31; GeneXpert MTB/RIF Ct values=20.8; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 163_6020093 Sample Type:Fail Time Point=w24; Osmolarity=252; MGIT (days)=9; GeneXpert MTB/RIF Ct values=23; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=1324.16; Comments=- SUBJECT_SAMPLE_FACTORS - 168_6017455 Sample Type:Fail Time Point=Dx; Osmolarity=266; MGIT (days)=4; GeneXpert MTB/RIF Ct values=14.5; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=1986.176; Comments=- SUBJECT_SAMPLE_FACTORS - 168_6017632 Sample Type:Fail Time Point=d7; Osmolarity=217; MGIT (days)=7; GeneXpert MTB/RIF Ct values=13.7; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 168_6017995 Sample Type:Fail Time Point=w4; Osmolarity=130; MGIT (days)=50; GeneXpert MTB/RIF Ct values=15.1; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=1477.952; Comments=- SUBJECT_SAMPLE_FACTORS - 168_6018319 Sample Type:Fail Time Point=w8; Osmolarity=374; MGIT (days)=50; GeneXpert MTB/RIF Ct values=23.8; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 168_6020172 Sample Type:Fail Time Point=w24; Osmolarity=266; MGIT (days)=5; GeneXpert MTB/RIF Ct values=19.2; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=1039.936; Comments=- SUBJECT_SAMPLE_FACTORS - 169_6017465 Sample Type:Fail Time Point=Dx; Osmolarity=289; MGIT (days)=4; GeneXpert MTB/RIF Ct values=27.2; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=1564.736; Comments=- SUBJECT_SAMPLE_FACTORS - 169_6017639 Sample Type:Fail Time Point=d7; Osmolarity=275; MGIT (days)=24; GeneXpert MTB/RIF Ct values=21; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 169_6017991 Sample Type:Fail Time Point=w4; Osmolarity=304; MGIT (days)=50; GeneXpert MTB/RIF Ct values=24.1; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=2552.512; Comments=- SUBJECT_SAMPLE_FACTORS - 169_6018329 Sample Type:Fail Time Point=w8; Osmolarity=283; MGIT (days)=50; GeneXpert MTB/RIF Ct values=28.5; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 169_6020182 Sample Type:Fail Time Point=w24; Osmolarity=76; MGIT (days)=20; GeneXpert MTB/RIF Ct values=20.2; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=224.7552; Comments=- SUBJECT_SAMPLE_FACTORS - 19_413660 Sample Type:Fail Time Point=Dx; Osmolarity=136; MGIT (days)=5; GeneXpert MTB/RIF Ct values=16.1; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=5392.832; Comments=- SUBJECT_SAMPLE_FACTORS - 19_413693 Sample Type:Fail Time Point=d7; Osmolarity=118; MGIT (days)=12; GeneXpert MTB/RIF Ct values=26.2; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 19_414721 Sample Type:Fail Time Point=w4; Osmolarity=170; MGIT (days)=15; GeneXpert MTB/RIF Ct values=24.4; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=6528; Comments=- SUBJECT_SAMPLE_FACTORS - 19_415454 Sample Type:Fail Time Point=w8; Osmolarity=219; MGIT (days)=3; GeneXpert MTB/RIF Ct values=24.1; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=Contamination (MGIT) SUBJECT_SAMPLE_FACTORS - 19_416777 Sample Type:Fail Time Point=w24; Osmolarity=258; MGIT (days)=11; GeneXpert MTB/RIF Ct values=25.9; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=1174.528; Comments=- SUBJECT_SAMPLE_FACTORS - 21_413701 Sample Type:Fail Time Point=Dx; Osmolarity=218; MGIT (days)=4; GeneXpert MTB/RIF Ct values=17.5; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=4724.48; Comments=- SUBJECT_SAMPLE_FACTORS - 21_413955 Sample Type:Fail Time Point=d7; Osmolarity=279; MGIT (days)=8; GeneXpert MTB/RIF Ct values=24.1; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 21_414539 Sample Type:Fail Time Point=w4; Osmolarity=244; MGIT (days)=5; GeneXpert MTB/RIF Ct values=21; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=3859.328; Comments=- SUBJECT_SAMPLE_FACTORS - 21_415469 Sample Type:Fail Time Point=w8; Osmolarity=190; MGIT (days)=1; GeneXpert MTB/RIF Ct values=20.4; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=Contamination (MGIT) SUBJECT_SAMPLE_FACTORS - 21_417709 Sample Type:Fail Time Point=w24; Osmolarity=197; MGIT (days)=6; GeneXpert MTB/RIF Ct values=22.3; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=5271.232; Comments=- SUBJECT_SAMPLE_FACTORS - 22_414462 Sample Type:Recur Time Point=Dx; Osmolarity=193; MGIT (days)=7; GeneXpert MTB/RIF Ct values=26.6; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=528.8704; Comments=- SUBJECT_SAMPLE_FACTORS - 22_414616 Sample Type:Recur Time Point=d7; Osmolarity=234; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 22_415083 Sample Type:Recur Time Point=w4; Osmolarity=268; MGIT (days)=50; GeneXpert MTB/RIF Ct values=33; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=479.7248; Comments=- SUBJECT_SAMPLE_FACTORS - 22_415489 Sample Type:Recur Time Point=w8; Osmolarity=288; MGIT (days)=1; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=Contamination (MGIT) SUBJECT_SAMPLE_FACTORS - 22_417071 Sample Type:Recur Time Point=w24; Osmolarity=273; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=172.9344; Comments=- SUBJECT_SAMPLE_FACTORS - 27_414865 Sample Type:Fail Time Point=Dx; Osmolarity=209; MGIT (days)=4; GeneXpert MTB/RIF Ct values=14.5; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=5671.488; Comments=- SUBJECT_SAMPLE_FACTORS - 27_415062 Sample Type:Fail Time Point=d7; Osmolarity=220; MGIT (days)=8; GeneXpert MTB/RIF Ct values=19.3; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 27_415512 Sample Type:Fail Time Point=w4; Osmolarity=120; MGIT (days)=1; GeneXpert MTB/RIF Ct values=29.5; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=5581.248; Comments=Contamination (MGIT) SUBJECT_SAMPLE_FACTORS - 27_415768 Sample Type:Fail Time Point=w8; Osmolarity=249; MGIT (days)=11; GeneXpert MTB/RIF Ct values=30.4; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 27_417177 Sample Type:Fail Time Point=w24; Osmolarity=137; MGIT (days)=18; GeneXpert MTB/RIF Ct values=29.3; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=5601.728; Comments=- SUBJECT_SAMPLE_FACTORS - 3_412447 Sample Type:Fail Time Point=Dx; Osmolarity=292; MGIT (days)=4; GeneXpert MTB/RIF Ct values=15.7; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=2434.56; Comments=- SUBJECT_SAMPLE_FACTORS - 3_412477 Sample Type:Fail Time Point=d7; Osmolarity=217; MGIT (days)=6; GeneXpert MTB/RIF Ct values=17.3; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 3_413084 Sample Type:Fail Time Point=w4; Osmolarity=273; MGIT (days)=4; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=2353.408; Comments=Error (GeneXpert) SUBJECT_SAMPLE_FACTORS - 3_413494 Sample Type:Fail Time Point=w8; Osmolarity=218; MGIT (days)=4; GeneXpert MTB/RIF Ct values=16.9; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 3_415915 Sample Type:Fail Time Point=w24; Osmolarity=265; MGIT (days)=3; GeneXpert MTB/RIF Ct values=17.2; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=2883.456; Comments=- SUBJECT_SAMPLE_FACTORS - 34_415815 Sample Type:Recur Time Point=Dx; Osmolarity=224; MGIT (days)=9; GeneXpert MTB/RIF Ct values=27.2; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=1309.952; Comments=- SUBJECT_SAMPLE_FACTORS - 34_415963 Sample Type:Recur Time Point=d7; Osmolarity=267; MGIT (days)=16; GeneXpert MTB/RIF Ct values=27; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 34_416720 Sample Type:Recur Time Point=w8; Osmolarity=326; MGIT (days)=28; GeneXpert MTB/RIF Ct values=34.3; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 34_417623 Sample Type:Recur Time Point=w24; Osmolarity=101; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=134.3616; Comments=- SUBJECT_SAMPLE_FACTORS - 34_417920 Sample Type:Recur Time Point=w4; Osmolarity=304; MGIT (days)=50; GeneXpert MTB/RIF Ct values=30.4; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=298.752; Comments=- SUBJECT_SAMPLE_FACTORS - 36_417863 Sample Type:Healthy Time Point=Dx; Osmolarity=287; MGIT (days)=43; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=Contamination (MGIT) SUBJECT_SAMPLE_FACTORS - 38_417787 Sample Type:Healthy Time Point=Dx; Osmolarity=281; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 39_417770 Sample Type:Healthy Time Point=Dx; Osmolarity=341; MGIT (days)=7; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=Contamination (MGIT) SUBJECT_SAMPLE_FACTORS - 4_412467 Sample Type:Cure Time Point=Dx; Osmolarity=297; MGIT (days)=6; GeneXpert MTB/RIF Ct values=22.7; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=5863.936; Comments=- SUBJECT_SAMPLE_FACTORS - 4_412676 Sample Type:Cure Time Point=d7; Osmolarity=229; MGIT (days)=12; GeneXpert MTB/RIF Ct values=23.2; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 4_413165 Sample Type:Cure Time Point=w4; Osmolarity=246; MGIT (days)=16; GeneXpert MTB/RIF Ct values=26.2; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=2233.28; Comments=- SUBJECT_SAMPLE_FACTORS - 4_413529 Sample Type:Cure Time Point=w8; Osmolarity=243; MGIT (days)=50; GeneXpert MTB/RIF Ct values=30.8; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 4_415983 Sample Type:Cure Time Point=w24; Osmolarity=248; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=116.2048; Comments=- SUBJECT_SAMPLE_FACTORS - 41_416680 Sample Type:Cure Time Point=d7; Osmolarity=197; MGIT (days)=20; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 41_416839 Sample Type:Cure Time Point=w4; Osmolarity=339; MGIT (days)=16; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=167.4688; Comments=- SUBJECT_SAMPLE_FACTORS - 41_417796 Sample Type:Cure Time Point=Dx; Osmolarity=335; MGIT (days)=19; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=384.96; Comments=- SUBJECT_SAMPLE_FACTORS - 41_417812 Sample Type:Cure Time Point=w8; Osmolarity=244; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 41_452528 Sample Type:Cure Time Point=w24; Osmolarity=301; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=21.06048; Comments=- SUBJECT_SAMPLE_FACTORS - 42_416647 Sample Type:Cure Time Point=Dx; Osmolarity=152; MGIT (days)=4; GeneXpert MTB/RIF Ct values=18.7; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=1603.136; Comments=- SUBJECT_SAMPLE_FACTORS - 42_417082 Sample Type:Cure Time Point=w4; Osmolarity=195; MGIT (days)=7; GeneXpert MTB/RIF Ct values=15.8; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=753.472; Comments=- SUBJECT_SAMPLE_FACTORS - 42_417298 Sample Type:Cure Time Point=w8; Osmolarity=245; MGIT (days)=3; GeneXpert MTB/RIF Ct values=27.4; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 42_417730 Sample Type:Cure Time Point=d7; Osmolarity=197; MGIT (days)=50; GeneXpert MTB/RIF Ct values=29.7; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 42_452621 Sample Type:Cure Time Point=w24; Osmolarity=124; MGIT (days)=50; GeneXpert MTB/RIF Ct values=30.3; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=119.232; Comments=- SUBJECT_SAMPLE_FACTORS - 43_416684 Sample Type:Fail Time Point=Dx; Osmolarity=319; MGIT (days)=5; GeneXpert MTB/RIF Ct values=21.6; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=391.6736; Comments=- SUBJECT_SAMPLE_FACTORS - 43_416760 Sample Type:Fail Time Point=d7; Osmolarity=377; MGIT (days)=10; GeneXpert MTB/RIF Ct values=26.9; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 43_416824 Sample Type:Fail Time Point=w4; Osmolarity=332; MGIT (days)=18; GeneXpert MTB/RIF Ct values=27.5; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=286.1568; Comments=- SUBJECT_SAMPLE_FACTORS - 43_417332 Sample Type:Fail Time Point=w8; Osmolarity=343; MGIT (days)=22; GeneXpert MTB/RIF Ct values=27.8; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 43_452641 Sample Type:Fail Time Point=w24; Osmolarity=276; MGIT (days)=19; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=170.048; Comments=- SUBJECT_SAMPLE_FACTORS - 45_416796 Sample Type:Healthy Time Point=Dx; Osmolarity=224; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 48_452312 Sample Type:Healthy Time Point=Dx; Osmolarity=290; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 49_417104 Sample Type:Cure Time Point=Dx; Osmolarity=173; MGIT (days)=3; GeneXpert MTB/RIF Ct values=19.5; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=2400.192; Comments=- SUBJECT_SAMPLE_FACTORS - 49_417197 Sample Type:Cure Time Point=d7; Osmolarity=258; MGIT (days)=4; GeneXpert MTB/RIF Ct values=25.2; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=Contamination (MGIT) SUBJECT_SAMPLE_FACTORS - 49_417420 Sample Type:Cure Time Point=w4; Osmolarity=1103; MGIT (days)=14; GeneXpert MTB/RIF Ct values=28.6; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=2619.968; Comments=- SUBJECT_SAMPLE_FACTORS - 49_417599 Sample Type:Cure Time Point=w8; Osmolarity=232; MGIT (days)=50; GeneXpert MTB/RIF Ct values=31.1; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 49_452751 Sample Type:Cure Time Point=w24; Osmolarity=285; MGIT (days)=5; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=580.8576; Comments=Contamination (MGIT) SUBJECT_SAMPLE_FACTORS - 52_417241 Sample Type:Cure Time Point=Dx; Osmolarity=291; MGIT (days)=6; GeneXpert MTB/RIF Ct values=19.3; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=3267.136; Comments=- SUBJECT_SAMPLE_FACTORS - 52_417306 Sample Type:Cure Time Point=w4; Osmolarity=217; MGIT (days)=6; GeneXpert MTB/RIF Ct values=19.1; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=3187.52; Comments=- SUBJECT_SAMPLE_FACTORS - 52_417327 Sample Type:Cure Time Point=d7; Osmolarity=253; MGIT (days)=16; GeneXpert MTB/RIF Ct values=25.5; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 52_417612 Sample Type:Cure Time Point=w8; Osmolarity=199; MGIT (days)=50; GeneXpert MTB/RIF Ct values=29.8; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 52_453273 Sample Type:Cure Time Point=w24; Osmolarity=388; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=1291.52; Comments=- SUBJECT_SAMPLE_FACTORS - 53_417231 Sample Type:Cure Time Point=Dx; Osmolarity=243; MGIT (days)=4; GeneXpert MTB/RIF Ct values=15.7; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=10368; Comments=- SUBJECT_SAMPLE_FACTORS - 53_417276 Sample Type:Cure Time Point=d7; Osmolarity=305; MGIT (days)=9; GeneXpert MTB/RIF Ct values=20.5; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 53_417432 Sample Type:Cure Time Point=w4; Osmolarity=275; MGIT (days)=14; GeneXpert MTB/RIF Ct values=25.2; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=11968; Comments=- SUBJECT_SAMPLE_FACTORS - 53_452177 Sample Type:Cure Time Point=w8; Osmolarity=305; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 53_452557 Sample Type:Cure Time Point=w24; Osmolarity=314; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=553.0048; Comments=- SUBJECT_SAMPLE_FACTORS - 54_417397 Sample Type:Cure Time Point=Dx; Osmolarity=163; MGIT (days)=10; GeneXpert MTB/RIF Ct values=24.7; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=205.9776; Comments=- SUBJECT_SAMPLE_FACTORS - 54_417526 Sample Type:Cure Time Point=w4; Osmolarity=155; MGIT (days)=18; GeneXpert MTB/RIF Ct values=23.3; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=69.9712; Comments=- SUBJECT_SAMPLE_FACTORS - 54_417543 Sample Type:Cure Time Point=d7; Osmolarity=95; MGIT (days)=29; GeneXpert MTB/RIF Ct values=27.8; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 54_452300 Sample Type:Cure Time Point=w8; Osmolarity=130; MGIT (days)=8; GeneXpert MTB/RIF Ct values=31; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=Contamination (MGIT) SUBJECT_SAMPLE_FACTORS - 54_453981 Sample Type:Cure Time Point=w24; Osmolarity=88; MGIT (days)=50; GeneXpert MTB/RIF Ct values=29.3; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=123.7632; Comments=- SUBJECT_SAMPLE_FACTORS - 57_452199 Sample Type:Healthy Time Point=Dx; Osmolarity=231; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 6_412774 Sample Type:Healthy Time Point=Dx; Osmolarity=184; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 60_452228 Sample Type:Healthy Time Point=Dx; Osmolarity=154; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 62_452365 Sample Type:Healthy Time Point=Dx; Osmolarity=276; MGIT (days)=9; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=Contamination (MGIT) SUBJECT_SAMPLE_FACTORS - 63_452409 Sample Type:Healthy Time Point=Dx; Osmolarity=189; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 65_452417 Sample Type:Healthy Time Point=Dx; Osmolarity=288; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 67_452529 Sample Type:Healthy Time Point=Dx; Osmolarity=150; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 68_452463 Sample Type:Healthy Time Point=Dx; Osmolarity=312; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 70_452497 Sample Type:Cure Time Point=Dx; Osmolarity=260; MGIT (days)=4; GeneXpert MTB/RIF Ct values=19.5; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=2225.152; Comments=- SUBJECT_SAMPLE_FACTORS - 70_452598 Sample Type:Cure Time Point=d7; Osmolarity=209; MGIT (days)=9; GeneXpert MTB/RIF Ct values=18.6; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 70_452879 Sample Type:Cure Time Point=w4; Osmolarity=281; MGIT (days)=11; GeneXpert MTB/RIF Ct values=21.5; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=1851.648; Comments=- SUBJECT_SAMPLE_FACTORS - 70_453399 Sample Type:Cure Time Point=w8; Osmolarity=241; MGIT (days)=9; GeneXpert MTB/RIF Ct values=23.7; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 70_454358 Sample Type:Cure Time Point=w24; Osmolarity=335; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=526.9952; Comments=- SUBJECT_SAMPLE_FACTORS - 72_452579 Sample Type:Cure Time Point=Dx; Osmolarity=198; MGIT (days)=3; GeneXpert MTB/RIF Ct values=17.4; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=2463.744; Comments=- SUBJECT_SAMPLE_FACTORS - 72_452697 Sample Type:Cure Time Point=d7; Osmolarity=103; MGIT (days)=6; GeneXpert MTB/RIF Ct values=14.8; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=Contamination (MGIT) SUBJECT_SAMPLE_FACTORS - 72_452708 Sample Type:Cure Time Point=w4; Osmolarity=150; MGIT (days)=19; GeneXpert MTB/RIF Ct values=27.2; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=2202.624; Comments=- SUBJECT_SAMPLE_FACTORS - 72_453409 Sample Type:Cure Time Point=w8; Osmolarity=564; MGIT (days)=8; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 72_454467 Sample Type:Cure Time Point=w24; Osmolarity=123; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=360.6848; Comments=- SUBJECT_SAMPLE_FACTORS - 76_452740 Sample Type:Cure Time Point=d7; Osmolarity=286; MGIT (days)=10; GeneXpert MTB/RIF Ct values=26.9; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 76_453251 Sample Type:Cure Time Point=Dx; Osmolarity=278; MGIT (days)=7; GeneXpert MTB/RIF Ct values=27.6; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=8384; Comments=- SUBJECT_SAMPLE_FACTORS - 76_453628 Sample Type:Cure Time Point=w4; Osmolarity=571; MGIT (days)=11; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=8576; Comments=Error (GeneXpert) SUBJECT_SAMPLE_FACTORS - 76_453992 Sample Type:Cure Time Point=w8; Osmolarity=460; MGIT (days)=50; GeneXpert MTB/RIF Ct values=23.9; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 76_454831 Sample Type:Cure Time Point=w24; Osmolarity=598; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=832.32; Comments=- SUBJECT_SAMPLE_FACTORS - 77_453178 Sample Type:Cure Time Point=Dx; Osmolarity=226; MGIT (days)=5; GeneXpert MTB/RIF Ct values=19.6; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=3226.368; Comments=- SUBJECT_SAMPLE_FACTORS - 77_453331 Sample Type:Cure Time Point=d7; Osmolarity=136; MGIT (days)=10; GeneXpert MTB/RIF Ct values=22.5; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=Contamination (MGIT) SUBJECT_SAMPLE_FACTORS - 77_453575 Sample Type:Cure Time Point=w4; Osmolarity=414; MGIT (days)=14; GeneXpert MTB/RIF Ct values=30; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=1283.84; Comments=- SUBJECT_SAMPLE_FACTORS - 77_453869 Sample Type:Cure Time Point=w8; Osmolarity=32; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 77_454840 Sample Type:Cure Time Point=w24; Osmolarity=318; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=214.5152; Comments=- SUBJECT_SAMPLE_FACTORS - 84_450359 Sample Type:Cure Time Point=w24; Osmolarity=263; MGIT (days)=50; GeneXpert MTB/RIF Ct values=32.4; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=1100.672; Comments=- SUBJECT_SAMPLE_FACTORS - 84_454074 Sample Type:Cure Time Point=Dx; Osmolarity=334; MGIT (days)=4; GeneXpert MTB/RIF Ct values=17.1; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=5798.144; Comments=- SUBJECT_SAMPLE_FACTORS - 84_454302 Sample Type:Cure Time Point=d7; Osmolarity=293; MGIT (days)=8; GeneXpert MTB/RIF Ct values=20.4; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 84_454456 Sample Type:Cure Time Point=w4; Osmolarity=270; MGIT (days)=17; GeneXpert MTB/RIF Ct values=22.9; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=3977.792; Comments=- SUBJECT_SAMPLE_FACTORS - 84_454731 Sample Type:Cure Time Point=w8; Osmolarity=291; MGIT (days)=50; GeneXpert MTB/RIF Ct values=33.2; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 88_451006 Sample Type:Recur Time Point=w24; Osmolarity=318; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=376.8512; Comments=- SUBJECT_SAMPLE_FACTORS - 88_454578 Sample Type:Recur Time Point=Dx; Osmolarity=254; MGIT (days)=12; GeneXpert MTB/RIF Ct values=31.6; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=963.584; Comments=- SUBJECT_SAMPLE_FACTORS - 88_454619 Sample Type:Recur Time Point=d7; Osmolarity=248; MGIT (days)=15; GeneXpert MTB/RIF Ct values=29.7; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 88_454803 Sample Type:Recur Time Point=w4; Osmolarity=276; MGIT (days)=21; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=1275.328; Comments=- SUBJECT_SAMPLE_FACTORS - 88_455254 Sample Type:Recur Time Point=w8; Osmolarity=249; MGIT (days)=50; GeneXpert MTB/RIF Ct values=31.7; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 9_413017 Sample Type:Cure Time Point=Dx; Osmolarity=344; MGIT (days)=5; GeneXpert MTB/RIF Ct values=22.2; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=2981.952; Comments=- SUBJECT_SAMPLE_FACTORS - 9_413209 Sample Type:Cure Time Point=d7; Osmolarity=341; MGIT (days)=5; GeneXpert MTB/RIF Ct values=23.1; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 9_413423 Sample Type:Cure Time Point=w4; Osmolarity=305; MGIT (days)=9; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=1996.032; Comments=- SUBJECT_SAMPLE_FACTORS - 9_414448 Sample Type:Cure Time Point=w8; Osmolarity=207; MGIT (days)=23; GeneXpert MTB/RIF Ct values=34; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 9_416315 Sample Type:Cure Time Point=w24; Osmolarity=311; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=169.9776; Comments=- SUBJECT_SAMPLE_FACTORS - 93_450104 Sample Type:Recur Time Point=w8; Osmolarity=252; MGIT (days)=2; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 93_451939 Sample Type:Recur Time Point=w24; Osmolarity=52; MGIT (days)=3; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=34.95296; Comments=- SUBJECT_SAMPLE_FACTORS - 93_455155 Sample Type:Recur Time Point=Dx; Osmolarity=260; MGIT (days)=20; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=134.7776; Comments=- SUBJECT_SAMPLE_FACTORS - 93_455291 Sample Type:Recur Time Point=d7; Osmolarity=126; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 93_455371 Sample Type:Recur Time Point=w4; Osmolarity=222; MGIT (days)=27; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=80.1152; Comments=- SUBJECT_SAMPLE_FACTORS - 95_450006 Sample Type:Recur Time Point=w8; Osmolarity=300; MGIT (days)=19; GeneXpert MTB/RIF Ct values=27.2; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 95_451797 Sample Type:Recur Time Point=w24; Osmolarity=259; MGIT (days)=50; GeneXpert MTB/RIF Ct values=26.5; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=1446.656; Comments=- SUBJECT_SAMPLE_FACTORS - 95_454934 Sample Type:Recur Time Point=Dx; Osmolarity=318; MGIT (days)=3; GeneXpert MTB/RIF Ct values=21.3; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=5510.208; Comments=- SUBJECT_SAMPLE_FACTORS - 95_455274 Sample Type:Recur Time Point=d7; Osmolarity=171; MGIT (days)=8; GeneXpert MTB/RIF Ct values=18.3; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 95_455355 Sample Type:Recur Time Point=w4; Osmolarity=347; MGIT (days)=10; GeneXpert MTB/RIF Ct values=19.7; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=4489.92; Comments=- SUBJECT_SAMPLE_FACTORS - 99_450109 Sample Type:Cure Time Point=w4; Osmolarity=196; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=251.5648; Comments=- SUBJECT_SAMPLE_FACTORS - 99_450530 Sample Type:Cure Time Point=w8; Osmolarity=296; MGIT (days)=8; GeneXpert MTB/RIF Ct values=22; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 99_455509 Sample Type:Cure Time Point=Dx; Osmolarity=145; MGIT (days)=13; GeneXpert MTB/RIF Ct values=22.2; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=599.1872; Comments=- SUBJECT_SAMPLE_FACTORS - 99_455537 Sample Type:Cure Time Point=d7; Osmolarity=61; MGIT (days)=10; GeneXpert MTB/RIF Ct values=21.6; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - 99_6016048 Sample Type:Cure Time Point=w24; Osmolarity=199; MGIT (days)=50; GeneXpert MTB/RIF Ct values=40; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=31.46048; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS16661 Sample Type:INDEX Time Point=-; Osmolarity=48; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS16663 Sample Type:TST- Time Point=-; Osmolarity=77; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS16675 Sample Type:TST- Time Point=-; Osmolarity=69; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS16682 Sample Type:INDEX Time Point=-; Osmolarity=68; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS16713 Sample Type:INDEX Time Point=-; Osmolarity=34; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS16714 Sample Type:TST+ Time Point=-; Osmolarity=35; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS16725 Sample Type:TST- Time Point=-; Osmolarity=66; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS16726 Sample Type:TST+ Time Point=-; Osmolarity=75; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS16841 Sample Type:INDEX Time Point=-; Osmolarity=34; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS16843 Sample Type:TST- Time Point=-; Osmolarity=155; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS16844 Sample Type:TST- Time Point=-; Osmolarity=93; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS16861 Sample Type:INDEX Time Point=-; Osmolarity=38; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS16862 Sample Type:TST+ Time Point=-; Osmolarity=81; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS16863 Sample Type:TST+ Time Point=-; Osmolarity=61; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS16868 Sample Type:INDEX Time Point=-; Osmolarity=76; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS16869 Sample Type:TST- Time Point=-; Osmolarity=47; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS16870 Sample Type:TST- Time Point=-; Osmolarity=88; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS16876 Sample Type:TST+ Time Point=-; Osmolarity=82; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS16877 Sample Type:TST- Time Point=-; Osmolarity=119; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS16878 Sample Type:TST+ Time Point=-; Osmolarity=94; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS16879 Sample Type:TST+ Time Point=-; Osmolarity=113; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS16884 Sample Type:INDEX Time Point=-; Osmolarity=96; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS16885 Sample Type:TST+ Time Point=-; Osmolarity=44; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS16924 Sample Type:TST- Time Point=-; Osmolarity=83; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS16925 Sample Type:TST- Time Point=-; Osmolarity=83; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS16926 Sample Type:TST- Time Point=-; Osmolarity=143; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS16951 Sample Type:INDEX Time Point=-; Osmolarity=47; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS16952 Sample Type:TST+ Time Point=-; Osmolarity=154; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS16955 Sample Type:TST- Time Point=-; Osmolarity=144; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS17012 Sample Type:INDEX Time Point=-; Osmolarity=33; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS17013 Sample Type:TST- Time Point=-; Osmolarity=59; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS17014 Sample Type:TST+ Time Point=-; Osmolarity=26; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS17027 Sample Type:INDEX Time Point=-; Osmolarity=36; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS17028 Sample Type:TST- Time Point=-; Osmolarity=141; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS17029 Sample Type:TST+ Time Point=-; Osmolarity=90; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- SUBJECT_SAMPLE_FACTORS - KCHS17030 Sample Type:TST+ Time Point=-; Osmolarity=120; MGIT (days)=-; GeneXpert MTB/RIF Ct values=-; Combined Total Glycolytic Activity (COM TGAI) from PET-CT=-; Comments=- #COLLECTION CO:COLLECTION_SUMMARY Urine was collected and frozen at -20 for storage. Prior to analysis, urine was CO:COLLECTION_SUMMARY thawed and centrifuged to remove particulates. CO:SAMPLE_TYPE Urine #TREATMENT TR:TREATMENT_SUMMARY Urine was analyzed by LC-MS #SAMPLEPREP SP:SAMPLEPREP_SUMMARY Urine was thawed on ice and centrifuged to remove particulates prior to SP:SAMPLEPREP_SUMMARY analysis. #CHROMATOGRAPHY CH:CHROMATOGRAPHY_TYPE Reversed phase CH:INSTRUMENT_NAME Agilent 1200 CH:COLUMN_NAME Atlantis T3 reverse-phase C18 3.5µm column (2.1 by 150mm CH:FLOW_GRADIENT 100% Solvent A to 90% Solvent B CH:FLOW_RATE 0.25 ml/min CH:COLUMN_TEMPERATURE 30 CH:SOLVENT_A 0.1% Formic Acid in Water CH:SOLVENT_B 0.1% Formic Acid in Methanol #ANALYSIS AN:ANALYSIS_TYPE MS AN:ANALYSIS_PROTOCOL_FILE SLC1G_Methods AN:DATA_FORMAT .d #MS MS:MS_COMMENTS - MS:INSTRUMENT_NAME Agilent 6520 QTOF MS:INSTRUMENT_TYPE QTOF MS:MS_TYPE ESI MS:ION_MODE POSITIVE MS:CAPILLARY_VOLTAGE 2000 V MS:COLLISION_ENERGY 10 V MS:DRY_GAS_FLOW 8 L/min MS:FRAGMENT_VOLTAGE 120 V MS:NEBULIZER 45 psi MS:OCTPOLE_VOLTAGE 750 V MS:SCANNING_CYCLE 1.2 spectra/sec MS:SCANNING_RANGE 100-1700 m/z MS:SKIMMER_VOLTAGE 60 V #MS_METABOLITE_DATA MS_METABOLITE_DATA:UNITS counts MS_METABOLITE_DATA_START Samples 93_455155 137_6015177 52_453273 130_6016222 43_417332 142_6015471 163_6020093 4_415983 101_450052 142_6016435 41_416680 95_455274 99_450109 43_416684 53_452177 137_6016220 21_417709 52_417327 72_452697 152_6017317 27_417177 140_6016195 142_6016207 169_6017991 84_454731 52_417306 130_6015197 163_6017429 88_454803 152_6017746 52_417241 3_413494 21_413701 21_414539 112_6015022 41_416839 140_6015623 144_6017147 152_6016992 49_417420 45_416796 19_414721 9_414448 53_452557 53_417432 9_413423 6_412774 93_455371 67_452529 163_6018193 53_417231 144_6019586 140_6018311 169_6017639 9_416315 72_452708 140_6016433 169_6018329 93_455291 95_451797 77_453869 10_413255 101_455555 137_6015809 4_412676 19_416777 142_6015673 21_415469 3_412477 169_6017465 95_455355 77_453178 53_417276 84_454074 42_417730 99_450530 3_413084 72_452579 133_6017982 168_6018319 22_415489 133_6015125 41_417796 27_415512 19_415454 168_6020172 36_417863 49_417104 49_417197 112_451057 152_6016782 34_417623 152_6019754 41_452528 101_450281 22_414462 72_454467 77_454840 49_417599 95_450006 169_6020182 101_450624 144_6016764 76_453251 95_454934 130_6015602 19_413660 93_451939 19_413693 144_6017656 77_453575 27_415062 76_452740 112_451762 4_413529 84_454302 41_417812 22_415083 84_454456 60_452228 39_417770 112_6016968 101_6015637 130_6015094 76_453992 9_413017 34_417920 72_453409 42_452621 48_452312 3_412447 168_6017995 77_453331 140_6015715 62_452365 70_452497 93_450104 88_451006 88_455254 76_453628 43_452641 88_454619 22_417071 54_452300 99_455509 68_452463 21_413955 137_6015271 4_412467 3_415915 49_452751 43_416824 70_452598 99_6016048 65_452417 70_454358 38_417787 88_454578 42_417298 163_6017645 168_6017455 34_415815 42_417082 99_455537 54_417526 54_417397 63_452409 133_6015265 112_451332 27_414865 34_416720 4_413165 54_417543 163_6017331 70_453399 130_6018022 34_415963 27_415768 76_454831 22_414616 142_6018238 144_6016655 168_6017632 9_413209 52_417612 54_453981 42_416647 57_452199 84_450359 43_416760 133_6015609 70_452879 137_6018150 Factors Sample Type:Recur Sample Type:Recur Sample Type:Cure Sample Type:Recur Sample Type:Fail Sample Type:Recur Sample Type:Fail Sample Type:Cure Sample Type:Recur Sample Type:Recur Sample Type:Cure Sample Type:Recur Sample Type:Cure Sample Type:Fail Sample Type:Cure Sample Type:Recur Sample Type:Fail Sample Type:Cure Sample Type:Cure Sample Type:Recur Sample Type:Fail Sample Type:Recur Sample Type:Recur Sample Type:Fail Sample Type:Cure Sample Type:Cure Sample Type:Recur Sample Type:Fail Sample Type:Recur Sample Type:Recur Sample Type:Cure Sample Type:Fail Sample Type:Fail Sample Type:Fail Sample Type:Recur Sample Type:Cure Sample Type:Recur Sample Type:Cure Sample Type:Recur Sample Type:Cure Sample Type:Healthy Sample Type:Fail Sample Type:Cure Sample Type:Cure Sample Type:Cure Sample Type:Cure Sample Type:Healthy Sample Type:Recur Sample Type:Healthy Sample Type:Fail Sample Type:Cure Sample Type:Cure Sample Type:Recur Sample Type:Fail Sample Type:Cure Sample Type:Cure Sample Type:Recur Sample Type:Fail Sample Type:Recur Sample Type:Recur Sample Type:Cure Sample Type:Healthy Sample Type:Recur Sample Type:Recur Sample Type:Cure Sample Type:Fail Sample Type:Recur Sample Type:Fail Sample Type:Fail Sample Type:Fail Sample Type:Recur Sample Type:Cure Sample Type:Cure Sample Type:Cure Sample Type:Cure Sample Type:Cure Sample Type:Fail Sample Type:Cure Sample Type:Cure Sample Type:Fail Sample Type:Recur Sample Type:Cure Sample Type:Cure Sample Type:Fail Sample Type:Fail Sample Type:Fail Sample Type:Healthy Sample Type:Cure Sample Type:Cure Sample Type:Recur Sample Type:Recur Sample Type:Recur Sample Type:Recur Sample Type:Cure Sample Type:Recur Sample Type:Recur Sample Type:Cure Sample Type:Cure Sample Type:Cure Sample Type:Recur Sample Type:Fail Sample Type:Recur Sample Type:Cure Sample Type:Cure Sample Type:Recur Sample Type:Recur Sample Type:Fail Sample Type:Recur Sample Type:Fail Sample Type:Cure Sample Type:Cure Sample Type:Fail Sample Type:Cure Sample Type:Recur Sample Type:Cure Sample Type:Cure Sample Type:Cure Sample Type:Recur Sample Type:Cure Sample Type:Healthy Sample Type:Healthy Sample Type:Recur Sample Type:Recur Sample Type:Recur Sample Type:Cure Sample Type:Cure Sample Type:Recur Sample Type:Cure Sample Type:Cure Sample Type:Healthy Sample Type:Fail Sample Type:Fail Sample Type:Cure Sample Type:Recur Sample Type:Healthy Sample Type:Cure Sample Type:Recur Sample Type:Recur Sample Type:Recur Sample Type:Cure Sample Type:Fail Sample Type:Recur Sample Type:Recur Sample Type:Cure Sample Type:Cure Sample Type:Healthy Sample Type:Fail Sample Type:Recur Sample Type:Cure Sample Type:Fail Sample Type:Cure Sample Type:Fail Sample Type:Cure Sample Type:Cure Sample Type:Healthy Sample Type:Cure Sample Type:Healthy Sample Type:Recur Sample Type:Cure Sample Type:Fail Sample Type:Fail Sample Type:Recur Sample Type:Cure Sample Type:Cure Sample Type:Cure Sample Type:Cure Sample Type:Healthy Sample Type:Cure Sample Type:Recur Sample Type:Fail Sample Type:Recur Sample Type:Cure Sample Type:Cure Sample Type:Fail Sample Type:Cure Sample Type:Recur Sample Type:Recur Sample Type:Fail Sample Type:Cure Sample Type:Recur Sample Type:Recur Sample Type:Cure Sample Type:Fail Sample Type:Cure Sample Type:Cure Sample Type:Cure Sample Type:Cure Sample Type:Healthy Sample Type:Cure Sample Type:Fail Sample Type:Cure Sample Type:Cure Sample Type:Recur SLC1G 159220.7202 505865.3126 209615.1615 131531.6005 138997.9794 926173.1011 329445.2192 252025.686 179561.5291 858850.9214 68119.96219 380878.0858 285966.6481 328187.8785 324627.5123 40297.56423 462068.858 611131.0156 57440.60764 46998.99339 166136.053 115914.0768 243551.267 421979.3248 686359.2494 304735.9047 422311.9926 265544.5683 165097.3053 50374.58393 973824.3762 968244.5091 877727.8294 631334.9354 278028.2929 155583.2959 293306.6053 119583.2903 229743.4877 709697.0055 271493.8197 654694.7831 206569.0868 284072.6986 421257.665 419077.8575 74972.80839 142578.0359 23083.09151 153079.6372 811720.468 105549.7 116029.9856 459712.2564 72337.3988 68849.45505 131578.7185 514645.6681 56439.21279 255814.0286 11818.20071 507155.9959 520024.1182 333272.6249 479979.331 823147.882 147425.5886 420579.7019 250850.8625 637947.1724 444938.1177 392787.6255 843412.2516 2002335.045 294518.4134 237153.4098 705599.8949 729943.2776 61945.36657 421643.3349 523202.0879 574662.4708 181398.2358 137790.9236 241835.9331 217478.391 268838.8227 995773.4891 1339834.496 1634913.262 615334.2932 46984.45821 209748.5234 227828.2905 192886.9319 361182.4906 50651.7684 63076.75285 329584.2579 453589.9586 73358.66105 231553.6075 158622.7779 423357.4348 1404526.639 188818.0328 1983497.379 27106.65201 898896.3124 871295.6551 111028.9085 533435.3971 139621.3945 216879.2991 158808.6124 1577486 49487.43101 342973.3061 2169186.022 48477.56132 347898.4983 858349.673 70716.87086 1437099.851 359314.808 1135598.354 140630.0241 176930.5997 34295.09038 249195.4357 398214.3499 74490.86818 65318.97154 205199.98 625281.0076 902859.0792 175081.5955 275055.9148 413258.2382 242314.665 43692.90966 280972.7176 211073.3821 165981.07 837851.7994 232805.6232 437219.9892 151444.9083 1198735.485 639711.3565 272420.3841 97397.60202 64306.48538 55396.0267 232302.4402 210893.7894 186873.2844 278822.5472 119779.2953 171221.0948 431742.1584 178554.9183 148800.937 90018.40188 97174.69864 178436.223 310505.105 211756.7627 985067.3321 665391.6336 97027.58447 180079.724 36225.52724 217066.8966 380523.72 42911.28674 76862.53282 328082.6302 148279.5298 508109.6667 20576.7936 477374.4584 214146.5286 657734.1537 178792.7957 47639.04716 238718.5346 160828.097 369055.2577 184751.7123 211279.3688 276426.6365 49690.61321 MS_METABOLITE_DATA_END #METABOLITES METABOLITES_START metabolite_name retention time m/z SLC1G 27.9 875.36 METABOLITES_END #END