MGP Database

MGP000382

Ontology/Pathway Information

Entrez Gene ID776
Gene Namecalcium channel, voltage-dependent, L type, alpha 1D subunit
Gene Symbol CACNA1D
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005886 ISS:BHF-UCLCplasma membrane
GO:0005891 IDA:UniProtKBCvoltage-gated calcium channel complex
GO:0030018 ISS:BHF-UCLCZ disc
GO:0051393 IPI:BHF-UCLFalpha-actinin binding
GO:0030506 ISS:BHF-UCLFankyrin binding
GO:0008331 IEA:EnsemblFhigh voltage-gated calcium channel activity
GO:0046872 IEA:UniProtKB-KWFmetal ion binding
GO:0005245 IDA:UniProtKBFvoltage-gated calcium channel activity
GO:0086007 IC:BHF-UCLFvoltage-gated calcium channel activity involved in cardiac muscle cell action potential
GO:0086059 IMP:BHF-UCLFvoltage-gated calcium channel activity involved SA node cell action potential
GO:0007188 ISS:BHF-UCLPadenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0007411 TAS:ReactomePaxon guidance
GO:0070509 IDA:BHF-UCLPcalcium ion import
GO:0070588 ISS:BHF-UCLPcalcium ion transmembrane transport
GO:0006816 IDA:UniProtKBPcalcium ion transport
GO:0006112 TAS:ReactomePenergy reserve metabolic process
GO:0086010 IBA:RefGenomePmembrane depolarization during action potential
GO:0086012 IC:BHF-UCLPmembrane depolarization during cardiac muscle cell action potential
GO:0086052 IMP:BHF-UCLPmembrane repolarization during SA node cell action potential
GO:0051928 IDA:BHF-UCLPpositive regulation of calcium ion transport
GO:0060372 ISS:BHF-UCLPregulation of atrial cardiac muscle cell membrane repolarization
GO:0086091 IMP:BHF-UCLPregulation of heart rate by cardiac conduction
GO:0050796 TAS:ReactomePregulation of insulin secretion
GO:1901379 ISS:BHF-UCLPregulation of potassium ion transmembrane transport
GO:1901016 ISS:BHF-UCLPregulation of potassium ion transmembrane transporter activity
GO:0007605 IMP:BHF-UCLPsensory perception of sound
GO:0044281 TAS:ReactomePsmall molecule metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_18339Adrenaline,noradrenaline inhibits insulin secretion
REACT_18266Axon guidance
REACT_111045Developmental Biology
REACT_1505Integration of energy metabolism
REACT_111217Metabolism
REACT_18312NCAM1 interactions
REACT_18334NCAM signaling for neurite out-growth
REACT_18325Regulation of insulin secretion
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