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MGP001230

UniProt Annotations

Entry Information
Gene Nameglucagon-like peptide 1 receptor
Protein EntryGLP1R_HUMAN
UniProt IDP43220
SpeciesHuman
Comments
Comment typeDescription
FunctionThis is a receptor for glucagon-like peptide 1. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
PtmN-glycosylation enhances cell surface expression and lengthens receptor half-life by preventing degradation in the ER. {ECO:0000269|PubMed:22412906}.
SimilarityBelongs to the G-protein coupled receptor 2 family. {ECO:0000305}.
Subcellular LocationCell membrane; Multi-pass membrane protein.
SubunitMay form homodimers and heterodimers with GIPR. {ECO:0000269|PubMed:18287102, ECO:0000269|PubMed:22412906}.
Web ResourceName=NIEHS-SNPs; URL="http://egp.gs.washington.edu/data/glp1r/";
Web ResourceName=Wikipedia; Note=Glucagon-like peptide 1 entry; URL="http://en.wikipedia.org/wiki/Glucagon-like_peptide-1";
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