MGP Database

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MGP002607

Ontology/Pathway Information

Entrez Gene ID5972
Gene Namerenin
Gene Symbol REN
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IEA:EnsemblCcytoplasm
GO:0005576 TAS:ReactomeCextracellular region
GO:0005615 IDA:HGNCCextracellular space
GO:0005886 TAS:ReactomeCplasma membrane
GO:0004190 IDA:HGNCFaspartic-type endopeptidase activity
GO:0008233 IDA:HGNCFpeptidase activity
GO:0005102 IPI:HGNCFreceptor binding
GO:0002003 IDA:HGNCPangiotensin maturation
GO:0050435 IEA:EnsemblPbeta-amyloid metabolic process
GO:0048469 IEA:EnsemblPcell maturation
GO:0044267 TAS:ReactomePcellular protein metabolic process
GO:0035690 IEA:EnsemblPcellular response to drug
GO:0042756 IEA:EnsemblPdrinking behavior
GO:0009755 IEA:EnsemblPhormone-mediated signaling pathway
GO:0001822 IMP:BHF-UCLPkidney development
GO:0008584 IEA:EnsemblPmale gonad development
GO:0001823 IEA:EnsemblPmesonephros development
GO:0006508 IDA:HGNCPproteolysis
GO:0008217 TAS:ProtIncPregulation of blood pressure
GO:0043408 IDA:HGNCPregulation of MAPK cascade
GO:0002018 IEA:EnsemblPrenin-angiotensin regulation of aldosterone production
GO:0051591 IEA:EnsemblPresponse to cAMP
GO:0070305 IEA:EnsemblPresponse to cGMP
GO:0035902 IEA:EnsemblPresponse to immobilization stress
GO:0032496 IEA:EnsemblPresponse to lipopolysaccharide
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_147707Metabolism of Angiotensinogen to Angiotensins
REACT_17015Metabolism of proteins
REACT_160078Peptide hormone metabolism
SMP Pathway Links
SMP IDDescription
SMP00587Angiotensin Metabolism
SMP00145Benazepril Action Pathway
SMP00158Candesartan Action Pathway
SMP00146Captopril Action Pathway
SMP00147Cilazapril Action Pathway
SMP00148Enalapril Action Pathway
SMP00159Eprosartan Action Pathway
SMP00160Forasartan Action Pathway
SMP00149Fosinopril Action Pathway
SMP00161Irbesartan Action Pathway
SMP00150Lisinopril Action Pathway
SMP00162Losartan Action Pathway
SMP00151Moexipril Action Pathway
SMP00163Olmesartan Action Pathway
SMP00152Perindopril Action Pathway
SMP00153Quinapril Action Pathway
SMP00154Ramipril Action Pathway
SMP00155Rescinnamine Action Pathway
SMP00156Spirapril Action Pathway
SMP00164Telmisartan Action Pathway
SMP00733Temocapril Action Pathway
SMP00157Trandolapril Action Pathway
SMP00165Valsartan Action Pathway
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