MGP Database

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MGP003765

Ontology/Pathway Information

Entrez Gene ID8997
Gene Namekalirin, RhoGEF kinase
Gene Symbol KALRN
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0015629 TAS:ProtIncCactin cytoskeleton
GO:0005829 TAS:ReactomeCcytosol
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005524 IEA:UniProtKB-KWFATP binding
GO:0005085 TAS:ProtIncFguanyl-nucleotide exchange factor activity
GO:0046872 IEA:UniProtKB-KWFmetal ion binding
GO:0004674 TAS:ProtIncFprotein serine/threonine kinase activity
GO:0005089 IEA:InterProFRho guanyl-nucleotide exchange factor activity
GO:0097190 TAS:ReactomePapoptotic signaling pathway
GO:0035556 ISS:HGNCPintracellular signal transduction
GO:0007399 ISS:HGNCPnervous system development
GO:0048011 TAS:ReactomePneurotrophin TRK receptor signaling pathway
GO:0043065 TAS:ReactomePpositive regulation of apoptotic process
GO:0043547 TAS:GOCPpositive regulation of GTPase activity
GO:0006468 TAS:ProtIncPprotein phosphorylation
GO:0051056 TAS:ReactomePregulation of small GTPase mediated signal transduction
GO:0007165 TAS:ProtIncPsignal transduction
GO:0007264 TAS:ReactomePsmall GTPase mediated signal transduction
GO:0016192 TAS:ProtIncPvesicle-mediated transport
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_18266Axon guidance
REACT_13720Cell death signalling via NRAGE, NRIF and NADE
REACT_111045Developmental Biology
REACT_263952EPHB-mediated forward signaling
REACT_264068EPH-Ephrin signaling
REACT_18407G alpha (12/13) signalling events
REACT_18283G alpha (q) signalling events
REACT_120966Gastrin-CREB signalling pathway via PKC and MAPK
REACT_19184GPCR downstream signaling
REACT_13638NRAGE signals death through JNK
REACT_13776p75 NTR receptor-mediated signalling
REACT_11051Rho GTPase cycle
REACT_14797Signaling by GPCR
REACT_11044Signaling by Rho GTPases
REACT_11061Signalling by NGF
REACT_111102Signal Transduction
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