#METABOLOMICS WORKBENCH zz_kl_bj_20171116_231625 DATATRACK_ID:1268 STUDY_ID:ST000903 ANALYSIS_ID:AN001470 PROJECT_ID:PR000627
VERSION             	1
CREATED_ON             	November 27, 2017, 10:58 am
#PROJECT
PR:PROJECT_TITLE                 	Metabolomic changes of chronic stressed rats in response to albiflorin treatment
PR:PROJECT_SUMMARY               	Depression is a complex and multifactorial disorder with various co-morbid
PR:PROJECT_SUMMARY               	symptoms. Current pharmacotherapies are limited by slow onset, low efficacy, and
PR:PROJECT_SUMMARY               	distressing side effects. Natural products are a robust source of new drugs. To
PR:PROJECT_SUMMARY               	understand the mechanisms of action of albiflorin, we examined the changes in
PR:PROJECT_SUMMARY               	global patterns of metabolism in the hippocampus and plasma of chronic stressed
PR:PROJECT_SUMMARY               	rats after albiflorin treatment using metabolomics
PR:INSTITUTE                     	Beijing Wonner Biotech. Co. Ltd
PR:LAST_NAME                     	Zhang
PR:FIRST_NAME                    	Zuoguang
PR:ADDRESS                       	No.9, Kexing Road, Fengtai, Beijing, Beijing, 101111, China
PR:EMAIL                         	leekefeng@hotmail.com
PR:PHONE                         	86-10-65670787
#STUDY
ST:STUDY_TITLE                   	Pharmacometabolomic analysis of rat hippocampus and plasma in response to
ST:STUDY_TITLE                   	chronic stress and albiflorin treament
ST:STUDY_TYPE                    	Animal study
ST:STUDY_SUMMARY                 	Male Sprague-Dawley (SD) rats were exposed to one random stressor per day for 35
ST:STUDY_SUMMARY                 	d. Following four weeks of stress exposure, rats with stress-induced
ST:STUDY_SUMMARY                 	depression-like behaviors were treated daily with either saline, fluoxetine or
ST:STUDY_SUMMARY                 	albiflorin for 7 days via intragastric gavage. Rat heparinized plasma was
ST:STUDY_SUMMARY                 	collected after drug treatment. After behavior tests, rats were sacrificed and
ST:STUDY_SUMMARY                 	the hippocampus was collected. Pharmacometabolomic analysis was conducted for
ST:STUDY_SUMMARY                 	both plasma and hippocampal samples
ST:INSTITUTE                     	Beijing Woner Biotech Co. Ltd
ST:LAST_NAME                     	Zhang
ST:FIRST_NAME                    	Zuoguang
ST:ADDRESS                       	No.9, Kexing Road, Fengtai, Beijing, Beijing, 101111, China
ST:EMAIL                         	leekefeng@hotmail.com
ST:PHONE                         	86-10-65670787
ST:NUM_GROUPS                    	4
ST:STUDY_COMMENTS                	Animal study
#SUBJECT
SU:SUBJECT_TYPE                  	Animal
SU:SUBJECT_SPECIES               	Rattus norvegicus
SU:TAXONOMY_ID                   	10116
SU:GENOTYPE_STRAIN               	Sprague-Dawley
SU:WEIGHT_OR_WEIGHT_RANGE        	180-220 g
SU:GENDER                        	Male
SU:ANIMAL_ANIMAL_SUPPLIER        	Beijing Huafukang Bioscience
SU:ANIMAL_LIGHT_CYCLE            	12:12 light-dark cycle
SU:ANIMAL_FEED                   	Standard food
SU:ANIMAL_WATER                  	Free access to food and water
#SUBJECT_SAMPLE_FACTORS:         	SUBJECT(optional)[tab]SAMPLE[tab]FACTORS(NAME:VALUE pairs separated by |)[tab]Additional sample data
SUBJECT_SAMPLE_FACTORS           	-	Beta_7_11	Genotype:Wild-type | Treatment:Saline	
SUBJECT_SAMPLE_FACTORS           	-	Beta_7_12	Genotype:Wild-type | Treatment:Saline	
SUBJECT_SAMPLE_FACTORS           	-	Beta_7_13	Genotype:Wild-type | Treatment:Saline	
SUBJECT_SAMPLE_FACTORS           	-	Beta_7_15	Genotype:Wild-type | Treatment:Saline	
SUBJECT_SAMPLE_FACTORS           	-	Beta_7_3	Genotype:Wild-type | Treatment:Saline	
SUBJECT_SAMPLE_FACTORS           	-	Beta_7_4	Genotype:Wild-type | Treatment:Saline	
SUBJECT_SAMPLE_FACTORS           	-	Beta_7_7	Genotype:Wild-type | Treatment:Saline	
SUBJECT_SAMPLE_FACTORS           	-	Beta_7_8	Genotype:Wild-type | Treatment:Saline	
SUBJECT_SAMPLE_FACTORS           	-	Beta_8_1	Genotype:CUMS model | Treatment:Saline	
SUBJECT_SAMPLE_FACTORS           	-	Beta_8_2	Genotype:CUMS model | Treatment:Saline	
SUBJECT_SAMPLE_FACTORS           	-	Beta_8_3	Genotype:CUMS model | Treatment:Saline	
SUBJECT_SAMPLE_FACTORS           	-	Beta_8_4	Genotype:CUMS model | Treatment:Saline	
SUBJECT_SAMPLE_FACTORS           	-	Beta_8_5	Genotype:CUMS model | Treatment:Saline	
SUBJECT_SAMPLE_FACTORS           	-	Beta_8_6	Genotype:CUMS model | Treatment:Saline	
SUBJECT_SAMPLE_FACTORS           	-	Beta_8_7	Genotype:CUMS model | Treatment:Saline	
SUBJECT_SAMPLE_FACTORS           	-	Beta_8_8	Genotype:CUMS model | Treatment:Saline	
SUBJECT_SAMPLE_FACTORS           	-	Beta_8_9	Genotype:CUMS model | Treatment:Saline	
SUBJECT_SAMPLE_FACTORS           	-	Beta_9_1	Genotype:CUMS model | Treatment:Fluoxetine	
SUBJECT_SAMPLE_FACTORS           	-	Beta_9_2	Genotype:CUMS model | Treatment:Fluoxetine	
SUBJECT_SAMPLE_FACTORS           	-	Beta_9_3	Genotype:CUMS model | Treatment:Fluoxetine	
SUBJECT_SAMPLE_FACTORS           	-	Beta_9_4	Genotype:CUMS model | Treatment:Fluoxetine	
SUBJECT_SAMPLE_FACTORS           	-	Beta_9_5	Genotype:CUMS model | Treatment:Fluoxetine	
SUBJECT_SAMPLE_FACTORS           	-	Beta_9_6	Genotype:CUMS model | Treatment:Fluoxetine	
SUBJECT_SAMPLE_FACTORS           	-	Beta_9_7	Genotype:CUMS model | Treatment:Fluoxetine	
SUBJECT_SAMPLE_FACTORS           	-	Beta_9_8	Genotype:CUMS model | Treatment:Fluoxetine	
SUBJECT_SAMPLE_FACTORS           	-	Beta_10_1	Genotype:CUMS model | Treatment:Albiflorin	
SUBJECT_SAMPLE_FACTORS           	-	Beta_10_2	Genotype:CUMS model | Treatment:Albiflorin	
SUBJECT_SAMPLE_FACTORS           	-	Beta_10_3	Genotype:CUMS model | Treatment:Albiflorin	
SUBJECT_SAMPLE_FACTORS           	-	Beta_10_4	Genotype:CUMS model | Treatment:Albiflorin	
SUBJECT_SAMPLE_FACTORS           	-	Beta_10_5	Genotype:CUMS model | Treatment:Albiflorin	
SUBJECT_SAMPLE_FACTORS           	-	Beta_10_6	Genotype:CUMS model | Treatment:Albiflorin	
SUBJECT_SAMPLE_FACTORS           	-	Beta_10_7	Genotype:CUMS model | Treatment:Albiflorin	
SUBJECT_SAMPLE_FACTORS           	-	Beta_10_8	Genotype:CUMS model | Treatment:Albiflorin	
#COLLECTION
CO:COLLECTION_SUMMARY            	Male Sprague-Dawley (SD) rats (180-220 g) were randomly assigned to control or
CO:COLLECTION_SUMMARY            	CUMS group. Rats in CUMS group were exposed to one random stressor per day for
CO:COLLECTION_SUMMARY            	35 d. Following four weeks of stress exposure, rats with stress-induced
CO:COLLECTION_SUMMARY            	depression-like behaviors were treated daily with either saline, Fluoxetine or
CO:COLLECTION_SUMMARY            	Albiflroin for 7 days via intragastric gavage.
CO:SAMPLE_TYPE                   	Plasma
CO:STORAGE_CONDITIONS            	-80C
CO:BLOOD_SERUM_OR_PLASMA         	Plasma
#TREATMENT
TR:TREATMENT_SUMMARY             	Following four weeks of stress exposure, rats with stress-induced
TR:TREATMENT_SUMMARY             	depression-like behaviors were treated daily with either saline, fluoxetine or
TR:TREATMENT_SUMMARY             	albiflorin for 7 days via intragastric gavage
TR:TREATMENT                     	Antidepressants
TR:TREATMENT_COMPOUND            	Albiflorin or fluoxetine
TR:TREATMENT_ROUTE               	Intragastric gavage
TR:TREATMENT_DOSE                	Albiflorin 7 mg/kg; fluoxetine 10 mg/kg
TR:TREATMENT_DOSEVOLUME          	0.2 ml/g
TR:TREATMENT_DOSEDURATION        	7 days
TR:TREATMENT_VEHICLE             	Saline
TR:ANIMAL_ANESTHESIA             	No
TR:ANIMAL_ACCLIMATION_DURATION   	No
TR:ANIMAL_FASTING                	No
#SAMPLEPREP
SP:SAMPLEPREP_SUMMARY            	Briefly, for plasma samples, 95 µl of plasma was mixed with 5 µl of isotope
SP:SAMPLEPREP_SUMMARY            	standards mix and extracted with 400 µl of pre-cold extraction buffer
SP:SAMPLEPREP_SUMMARY            	containing methanol/acetonitrile (50/50, v/v). The mixture was incubated on ice
SP:SAMPLEPREP_SUMMARY            	for 30 min and centrifuged for 10 min at 16,000 g and 4 ºC. The supernatant
SP:SAMPLEPREP_SUMMARY            	containing both polar and nonpolar metabolites was transferred to new tubes and
SP:SAMPLEPREP_SUMMARY            	stored at -80 ºC for metabolomic analysis
SP:EXTRACTION_METHOD             	methanol/acetonitrile (50/50, v/v) precipitation
SP:EXTRACT_STORAGE               	-80 ºC
SP:SAMPLE_DERIVATIZATION         	No
SP:SAMPLE_SPIKING                	Isotope standards
#CHROMATOGRAPHY
CH:CHROMATOGRAPHY_TYPE           	HILIC
CH:INSTRUMENT_NAME               	Waters ACQUITY UPLC
CH:COLUMN_NAME                   	Luna NH2 aminopropyl HPLC column
CH:FLOW_RATE                     	0.35 ml/min
CH:COLUMN_TEMPERATURE            	25 °C
CH:SOLVENT_A                     	95% watrer+5% acetonitrile+20 mM ammonium hydroxide+20 mM ammonium acetate, pH
CH:SOLVENT_A                     	9.0
CH:SOLVENT_B                     	100% acetonitrile
CH:COLUMN_PRESSURE               	2200 psi
CH:INJECTION_TEMPERATURE         	4 °C
CH:SAMPLE_INJECTION              	12 µl
CH:SAMPLE_LOOP_SIZE              	12
CH:RANDOMIZATION_ORDER           	Yes
#ANALYSIS
AN:ANALYSIS_TYPE                 	MS
AN:SOFTWARE_VERSION              	Analyst 1.6.2
#MS
MS:MS_COMMENTS                   	-
MS:INSTRUMENT_NAME               	ABI Sciex 6500 QTrap
MS:INSTRUMENT_TYPE               	Triple quadrupole
MS:MS_TYPE                       	ESI
MS:ION_MODE                      	POSITIVE
MS:COLLISION_ENERGY              	Compound dependent
MS:COLLISION_GAS                 	25
MS:MASS_ACCURACY                 	0.1 Da
MS:SOURCE_TEMPERATURE            	475 ºC
MS:SPRAY_VOLTAGE                 	5500 ºC
#MS_METABOLITE_DATA
MS_METABOLITE_DATA:UNITS         	AUC
MS_METABOLITE_DATA_START
Samples	Beta_10_1	Beta_10_2	Beta_10_3	Beta_10_4	Beta_10_5	Beta_10_6	Beta_10_7	Beta_10_8	Beta_8_1	Beta_8_2	Beta_8_3	Beta_8_4	Beta_8_5	Beta_8_6	Beta_8_7	Beta_8_8	Beta_8_9	Beta_9_1	Beta_9_2	Beta_9_3	Beta_9_4	Beta_9_5	Beta_9_6	Beta_9_7	Beta_9_8	Beta_7_11	Beta_7_12	Beta_7_13	Beta_7_15	Beta_7_3	Beta_7_4	Beta_7_7	Beta_7_8
Factors	Genotype:CUMS model | Treatment:Albiflorin	Genotype:CUMS model | Treatment:Albiflorin	Genotype:CUMS model | Treatment:Albiflorin	Genotype:CUMS model | Treatment:Albiflorin	Genotype:CUMS model | Treatment:Albiflorin	Genotype:CUMS model | Treatment:Albiflorin	Genotype:CUMS model | Treatment:Albiflorin	Genotype:CUMS model | Treatment:Albiflorin	Genotype:CUMS model | Treatment:Saline	Genotype:CUMS model | Treatment:Saline	Genotype:CUMS model | Treatment:Saline	Genotype:CUMS model | Treatment:Saline	Genotype:CUMS model | Treatment:Saline	Genotype:CUMS model | Treatment:Saline	Genotype:CUMS model | Treatment:Saline	Genotype:CUMS model | Treatment:Saline	Genotype:CUMS model | Treatment:Saline	Genotype:CUMS model | Treatment:Fluoxetine	Genotype:CUMS model | Treatment:Fluoxetine	Genotype:CUMS model | Treatment:Fluoxetine	Genotype:CUMS model | Treatment:Fluoxetine	Genotype:CUMS model | Treatment:Fluoxetine	Genotype:CUMS model | Treatment:Fluoxetine	Genotype:CUMS model | Treatment:Fluoxetine	Genotype:CUMS model | Treatment:Fluoxetine	Genotype:Wild-type | Treatment:Saline	Genotype:Wild-type | Treatment:Saline	Genotype:Wild-type | Treatment:Saline	Genotype:Wild-type | Treatment:Saline	Genotype:Wild-type | Treatment:Saline	Genotype:Wild-type | Treatment:Saline	Genotype:Wild-type | Treatment:Saline	Genotype:Wild-type | Treatment:Saline
Creatine	282000000.00	301000000.00	304000000.00	327000000.00	316000000.00	341000000.00	290000000.00	275000000.00	323000000.00	314000000.00	282000000.00	293000000.00	307000000.00	243000000.00	315000000.00	306000000.00	297000000.00	323000000.00	321000000.00	283000000.00	328000000.00	326000000.00	323000000.00	306000000.00	317000000.00	364000000.00	353000000.00	327000000.00	346000000.00	340000000.00	353000000.00	339000000.00	364000000.00
CoQ9	117000.00	43400.00	64500.00	79600.00	54900.00	33000.00	27900.00	61500.00	54200.00	39500.00	99800.00	89700.00	48600.00	95500.00	84400.00	80400.00	62000.00	30700.00	32700.00	27200.00	39000.00	53800.00	120000.00	56500.00	84900.00	34500.00	87200.00	38600.00	33600.00	44500.00	25900.00	30900.00	31900.00
CoQ9H2	19500.00	9960.00	16300.00	18700.00	12700.00	9270.00	11000.00	11200.00	17700.00	13300.00	16200.00	12800.00	13000.00	19600.00	14400.00	18300.00	12300.00	5640.00	10000.00	12500.00	12600.00	7800.00	18100.00	16800.00	20500.00	18500.00	18900.00	5910.00	12500.00	14000.00	4220.00	10300.00	7130.00
Retinol	49900.00	28400.00	46800.00	26600.00	24900.00	49900.00	41800.00	32800.00	43600.00	42500.00	27900.00	52600.00	52000.00	69400.00	35900.00	37000.00	30200.00	28700.00	42000.00	63400.00	29200.00	34400.00	40000.00	45100.00	41700.00	32800.00	27100.00	39000.00	32300.00	34400.00	64200.00	187000.00	41700.00
Alpha-Tocopherol	1510000.00	1220000.00	1330000.00	1210000.00	1400000.00	1180000.00	1330000.00	1240000.00	1470000.00	1040000.00	1620000.00	1460000.00	1040000.00	1490000.00	1640000.00	1730000.00	1500000.00	1380000.00	1160000.00	489000.00	1340000.00	1570000.00	1860000.00	1480000.00	1860000.00	1330000.00	1210000.00	1230000.00	1180000.00	1080000.00	1230000.00	1030000.00	1050000.00
Vitamin K2	1390000.00	920000.00	5070000.00	990000.00	1890000.00	1310000.00	2860000.00	1430000.00	1030000.00	1450000.00	3770000.00	1310000.00	965000.00	3300000.00	1400000.00	1220000.00	3040000.00	1690000.00	1210000.00	758000.00	1630000.00	2150000.00	1780000.00	1830000.00	11600000.00	1750000.00	2990000.00	1590000.00	4430000.00	1200000.00	1220000.00	1060000.00	1170000.00
Cholesterol	13000000.00	8500000.00	10100000.00	10400000.00	9740000.00	8340000.00	9700000.00	9900000.00	7300000.00	5000000.00	9270000.00	5170000.00	6130000.00	11300000.00	9990000.00	8970000.00	10000000.00	6730000.00	7510000.00	4300000.00	4230000.00	9410000.00	7930000.00	8150000.00	8520000.00	6830000.00	10900000.00	8900000.00	7170000.00	6990000.00	3740000.00	4330000.00	6560000.00
5,6-trans-25-Hydroxyvitamin D3	6120000.00	3200000.00	4290000.00	5060000.00	5350000.00	3430000.00	6860000.00	6650000.00	10100000.00	5030000.00	7070000.00	6950000.00	6720000.00	13000000.00	8740000.00	7910000.00	8880000.00	6630000.00	7870000.00	1610000.00	6950000.00	8570000.00	9600000.00	6560000.00	5220000.00	5800000.00	5570000.00	5650000.00	4990000.00	5950000.00	4900000.00	5510000.00	4720000.00
Retinal	80700.00	59300.00	98900.00	73600.00	57000.00	72100.00	95000.00	74000.00	34100.00	40900.00	71900.00	65900.00	55400.00	50500.00	51400.00	53400.00	49800.00	65200.00	57700.00	47100.00	77000.00	116000.00	54500.00	107000.00	42400.00	89700.00	99000.00	42900.00	86800.00	89600.00	71900.00	82300.00	70700.00
7-ketocholesterol	4120000.00	2220000.00	2650000.00	3070000.00	3850000.00	1940000.00	4470000.00	4210000.00	3450000.00	1900000.00	2400000.00	2190000.00	1950000.00	6790000.00	3390000.00	2950000.00	4760000.00	1910000.00	3280000.00	6640000.00	2490000.00	2910000.00	3650000.00	2200000.00	2540000.00	1340000.00	2010000.00	1770000.00	1260000.00	1330000.00	958000.00	846000.00	710000.00
Cer(d18:1/22:0 OH)	1070000.00	656000.00	638000.00	1040000.00	744000.00	744000.00	1140000.00	717000.00	1060000.00	378000.00	1070000.00	751000.00	615000.00	824000.00	733000.00	831000.00	966000.00	1000000.00	689000.00	140000.00	869000.00	1020000.00	1560000.00	722000.00	691000.00	752000.00	804000.00	1050000.00	732000.00	791000.00	607000.00	651000.00	684000.00
Cer(d18:1/18:0)	828000.00	631000.00	553000.00	940000.00	881000.00	813000.00	934000.00	805000.00	879000.00	279000.00	640000.00	662000.00	328000.00	502000.00	693000.00	627000.00	737000.00	973000.00	590000.00	101000.00	843000.00	754000.00	1130000.00	676000.00	546000.00	756000.00	625000.00	650000.00	546000.00	912000.00	536000.00	717000.00	614000.00
Cer(d18:1/22:0)	924000.00	617000.00	522000.00	1000000.00	973000.00	1050000.00	953000.00	967000.00	1300000.00	463000.00	952000.00	667000.00	655000.00	749000.00	702000.00	865000.00	1320000.00	1200000.00	746000.00	165000.00	1210000.00	929000.00	1870000.00	752000.00	544000.00	554000.00	845000.00	1020000.00	914000.00	1130000.00	1100000.00	1160000.00	842000.00
Cer(d18:1/24:0)	2720000.00	1980000.00	1160000.00	2490000.00	2810000.00	2630000.00	2010000.00	3290000.00	3720000.00	1250000.00	3010000.00	1910000.00	2100000.00	2670000.00	2240000.00	1910000.00	3350000.00	3150000.00	2290000.00	478000.00	3380000.00	2260000.00	4660000.00	2400000.00	1750000.00	1490000.00	1950000.00	2830000.00	2300000.00	3040000.00	3130000.00	3130000.00	2290000.00
Cer(d18:1/24:1)	9330000.00	7980000.00	5600000.00	8960000.00	9570000.00	9180000.00	9930000.00	6550000.00	11700000.00	4630000.00	8870000.00	9360000.00	6100000.00	9740000.00	9230000.00	8610000.00	11800000.00	9100000.00	7490000.00	1700000.00	9720000.00	8220000.00	14500000.00	8380000.00	5740000.00	6140000.00	7600000.00	9370000.00	8190000.00	9760000.00	7390000.00	9700000.00	7790000.00
Cer(d18:1/24:2)	4230000.00	2690000.00	2510000.00	3580000.00	3510000.00	3580000.00	4430000.00	2060000.00	4570000.00	1760000.00	3360000.00	3660000.00	2550000.00	3600000.00	4030000.00	3600000.00	4830000.00	4050000.00	3680000.00	727000.00	3740000.00	4090000.00	4870000.00	3690000.00	2530000.00	3590000.00	3870000.00	4980000.00	2770000.00	4160000.00	2980000.00	3690000.00	3940000.00
Cer(d18:1/25:0)	3230000.00	2970000.00	2410000.00	3740000.00	3340000.00	3380000.00	3810000.00	2110000.00	3740000.00	1670000.00	3250000.00	3040000.00	2300000.00	3030000.00	3400000.00	3350000.00	4280000.00	3710000.00	3300000.00	654000.00	3510000.00	3970000.00	4780000.00	3150000.00	2580000.00	2720000.00	3380000.00	4940000.00	2850000.00	4200000.00	2760000.00	3380000.00	2950000.00
Vitamin D3	1250000.00	901000.00	1070000.00	1090000.00	1280000.00	1000000.00	1260000.00	1420000.00	1110000.00	821000.00	1480000.00	1110000.00	1200000.00	1400000.00	1340000.00	1240000.00	1220000.00	1150000.00	1210000.00	3520000.00	1090000.00	1640000.00	1540000.00	1420000.00	1300000.00	1370000.00	1290000.00	1080000.00	1190000.00	1260000.00	1080000.00	918000.00	1040000.00
Cer(d18:1/23:0)	944000.00	716000.00	697000.00	1020000.00	902000.00	1120000.00	1090000.00	924000.00	1420000.00	569000.00	1200000.00	787000.00	866000.00	962000.00	917000.00	959000.00	1210000.00	1140000.00	879000.00	183000.00	1140000.00	1020000.00	1620000.00	994000.00	744000.00	798000.00	960000.00	1180000.00	906000.00	1150000.00	1150000.00	1090000.00	970000.00
N-oleoylethanolamine	852000.00	614000.00	654000.00	719000.00	554000.00	561000.00	606000.00	633000.00	440000.00	381000.00	555000.00	469000.00	571000.00	479000.00	456000.00	436000.00	427000.00	414000.00	423000.00	158000.00	473000.00	447000.00	471000.00	528000.00	383000.00	499000.00	424000.00	525000.00	573000.00	498000.00	394000.00	344000.00	471000.00
2-Arachidonylglycerol	272000.00	180000.00	282000.00	200000.00	494000.00	224000.00	325000.00	260000.00	148000.00	134000.00	193000.00	102000.00	129000.00	197000.00	132000.00	171000.00	122000.00	166000.00	134000.00	71400.00	146000.00	167000.00	145000.00	212000.00	191000.00	92800.00	147000.00	187000.00	170000.00	124000.00	92300.00	65900.00	124000.00
Testosterone	451000.00	275000.00	164000.00	146000.00	95700.00	135000.00	139000.00	59400.00	259000.00	133000.00	124000.00	179000.00	136000.00	125000.00	168000.00	189000.00	137000.00	94700.00	204000.00	173000.00	132000.00	170000.00	159000.00	137000.00	229000.00	261000.00	192000.00	242000.00	205000.00	146000.00	209000.00	126000.00	168000.00
PC(22:6/P-18:0)	90100.00	67600.00	70200.00	72100.00	83600.00	63500.00	83500.00	73200.00	75700.00	43100.00	162000.00	83300.00	54500.00	70000.00	56400.00	81400.00	67500.00	90500.00	60600.00	192000.00	126000.00	71200.00	98200.00	74500.00	114000.00	65100.00	74400.00	83100.00	66100.00	80900.00	62200.00	88500.00	74700.00
PC(16:0/16:0)	8910000.00	8020000.00	8950000.00	8550000.00	9130000.00	11200000.00	11600000.00	9250000.00	13100000.00	8270000.00	11800000.00	11800000.00	10900000.00	11000000.00	11300000.00	11800000.00	12900000.00	12900000.00	12300000.00	20300000.00	13200000.00	12500000.00	13500000.00	8660000.00	8840000.00	14000000.00	9930000.00	15600000.00	9850000.00	13800000.00	9900000.00	11900000.00	12500000.00
PC(16:0/18:1)	9840000.00	11400000.00	8800000.00	9210000.00	11600000.00	10400000.00	10900000.00	13400000.00	12100000.00	10400000.00	12100000.00	12000000.00	8080000.00	14700000.00	11600000.00	10500000.00	11400000.00	12800000.00	12100000.00	24300000.00	13200000.00	10500000.00	15600000.00	9760000.00	11500000.00	8320000.00	7530000.00	9530000.00	7390000.00	8850000.00	7550000.00	8010000.00	7300000.00
PC(18:0/18:2)	10500000.00	10700000.00	11000000.00	12100000.00	12300000.00	12800000.00	12200000.00	11400000.00	18500000.00	15100000.00	16000000.00	16200000.00	12900000.00	17700000.00	19700000.00	15000000.00	19600000.00	16200000.00	13200000.00	26600000.00	16000000.00	14200000.00	14500000.00	12700000.00	17200000.00	12100000.00	13800000.00	12700000.00	10200000.00	13300000.00	13100000.00	13800000.00	12300000.00
Corticosterone	857000.00	712000.00	629000.00	807000.00	759000.00	763000.00	677000.00	431000.00	778000.00	499000.00	617000.00	737000.00	760000.00	478000.00	659000.00	552000.00	896000.00	445000.00	782000.00	266000.00	475000.00	751000.00	683000.00	792000.00	914000.00	1190000.00	599000.00	825000.00	831000.00	1470000.00	956000.00	872000.00	684000.00
Choline	1730000.00	1870000.00	1520000.00	1710000.00	1200000.00	1770000.00	1550000.00	1300000.00	1430000.00	1840000.00	1460000.00	2020000.00	1780000.00	1600000.00	1550000.00	1690000.00	934000.00	1690000.00	1920000.00	2140000.00	2210000.00	1430000.00	2050000.00	1670000.00	1330000.00	1980000.00	1610000.00	1450000.00	1690000.00	1400000.00	2040000.00	1300000.00	1460000.00
Melatonin	123000.00	215000.00	134000.00	102000.00	172000.00	184000.00	153000.00	270000.00	124000.00	126000.00	117000.00	101000.00	278000.00	142000.00	195000.00	189000.00	71600.00	134000.00	248000.00	142000.00	220000.00	144000.00	62000.00	170000.00	139000.00	85700.00	111000.00	61300.00	145000.00	473000.00	112000.00	177000.00	106000.00
Niacinamide	72400000.00	74000000.00	73500000.00	75900000.00	76300000.00	82300000.00	50400000.00	62700000.00	48800000.00	50400000.00	59700000.00	56900000.00	58100000.00	46000000.00	53600000.00	68700000.00	63800000.00	89300000.00	77900000.00	65500000.00	72400000.00	79700000.00	77700000.00	78600000.00	70900000.00	102000000.00	76200000.00	76100000.00	72300000.00	130000000.00	77100000.00	60400000.00	73100000.00
PC(16:0/22:6)	2810000.00	1140000.00	2010000.00	2080000.00	2120000.00	1570000.00	2070000.00	1220000.00	2280000.00	1270000.00	2020000.00	2420000.00	2460000.00	1970000.00	1550000.00	2270000.00	1700000.00	1870000.00	2010000.00	4310000.00	2140000.00	1380000.00	2530000.00	1810000.00	2370000.00	2170000.00	1660000.00	1830000.00	1650000.00	1700000.00	1780000.00	1390000.00	2280000.00
PC(16:0/18:2)	7490000.00	8010000.00	7520000.00	8750000.00	8930000.00	9280000.00	8650000.00	7900000.00	12200000.00	9890000.00	10600000.00	10000000.00	6950000.00	11600000.00	10700000.00	9970000.00	11900000.00	9740000.00	10500000.00	17200000.00	11000000.00	10000000.00	11000000.00	8260000.00	10200000.00	7440000.00	7870000.00	8900000.00	6970000.00	8500000.00	8120000.00	7750000.00	7410000.00
PC(16:0/20:4)	4850000.00	4150000.00	3880000.00	5490000.00	4740000.00	3930000.00	5390000.00	3160000.00	5480000.00	4590000.00	5060000.00	5180000.00	5060000.00	5010000.00	4310000.00	5260000.00	5230000.00	4870000.00	5160000.00	10600000.00	5630000.00	4580000.00	5570000.00	4310000.00	5430000.00	4400000.00	4080000.00	5240000.00	3740000.00	4030000.00	5090000.00	4670000.00	4860000.00
PC(20:4/P-16:0)	660000.00	585000.00	659000.00	839000.00	583000.00	608000.00	725000.00	668000.00	842000.00	622000.00	775000.00	682000.00	628000.00	659000.00	641000.00	946000.00	722000.00	880000.00	694000.00	1530000.00	849000.00	971000.00	844000.00	849000.00	966000.00	922000.00	748000.00	826000.00	823000.00	909000.00	745000.00	648000.00	802000.00
Dodecenoylcarnitine	2210000.00	2200000.00	1570000.00	1730000.00	1050000.00	652000.00	398000.00	1990000.00	700000.00	1020000.00	1950000.00	1740000.00	1730000.00	909000.00	1030000.00	1330000.00	813000.00	849000.00	824000.00	2050000.00	872000.00	1200000.00	803000.00	2030000.00	1220000.00	985000.00	1200000.00	953000.00	852000.00	2550000.00	1780000.00	1040000.00	1650000.00
Glucosylceramide(18:1/16:0)	85100.00	63600.00	113000.00	115000.00	134000.00	89700.00	115000.00	73200.00	125000.00	172000.00	139000.00	202000.00	102000.00	104000.00	194000.00	143000.00	158000.00	243000.00	129000.00	78500.00	95600.00	147000.00	191000.00	122000.00	190000.00	113000.00	98500.00	167000.00	117000.00	138000.00	97000.00	136000.00	234000.00
L-Palmitoylcarnitine	899000.00	395000.00	384000.00	879000.00	202000.00	255000.00	272000.00	373000.00	320000.00	354000.00	371000.00	376000.00	509000.00	299000.00	273000.00	354000.00	435000.00	294000.00	459000.00	626000.00	305000.00	282000.00	231000.00	544000.00	287000.00	338000.00	748000.00	300000.00	316000.00	767000.00	352000.00	258000.00	384000.00
Oleoylcarnitine	21100000.00	14600000.00	21600000.00	19000000.00	8300000.00	8890000.00	6620000.00	18400000.00	7470000.00	10800000.00	14400000.00	13200000.00	19500000.00	8910000.00	6930000.00	11400000.00	6100000.00	10100000.00	10300000.00	10100000.00	9380000.00	10400000.00	8080000.00	26200000.00	14400000.00	16000000.00	16100000.00	13200000.00	11800000.00	40700000.00	11200000.00	8250000.00	23400000.00
Octadecanoylcarnitine	6470000.00	5050000.00	7310000.00	7070000.00	4090000.00	4810000.00	3630000.00	5280000.00	3990000.00	4470000.00	6070000.00	6340000.00	7060000.00	4290000.00	4080000.00	5020000.00	3700000.00	5160000.00	4730000.00	4070000.00	4890000.00	4990000.00	3440000.00	6960000.00	5740000.00	6690000.00	6870000.00	6070000.00	5340000.00	11300000.00	4700000.00	4230000.00	9570000.00
LysoPC(16:0)	33200000.00	35600000.00	36300000.00	34700000.00	37400000.00	33000000.00	35300000.00	34900000.00	36000000.00	36400000.00	34300000.00	38800000.00	36800000.00	38700000.00	40600000.00	36300000.00	35200000.00	36600000.00	43500000.00	33400000.00	36100000.00	32800000.00	42200000.00	35400000.00	36200000.00	31800000.00	30900000.00	35300000.00	35800000.00	34300000.00	33600000.00	33400000.00	33500000.00
Dodecanoylcarnitine	5400000.00	4540000.00	4130000.00	4200000.00	3010000.00	2020000.00	1830000.00	4980000.00	1480000.00	2760000.00	4200000.00	2760000.00	4810000.00	2560000.00	2150000.00	3220000.00	2160000.00	2500000.00	1990000.00	3680000.00	2700000.00	2340000.00	1900000.00	4920000.00	2530000.00	2510000.00	2250000.00	1980000.00	2100000.00	5130000.00	2300000.00	1820000.00	3340000.00
Myristoylcarnitine	11400000.00	9390000.00	10000000.00	10500000.00	5340000.00	4400000.00	3130000.00	10500000.00	3470000.00	5730000.00	8650000.00	6750000.00	10600000.00	6340000.00	4860000.00	7510000.00	4750000.00	4820000.00	4490000.00	5900000.00	5740000.00	5100000.00	4040000.00	13700000.00	6300000.00	6860000.00	6300000.00	6170000.00	4500000.00	15000000.00	5470000.00	4450000.00	9710000.00
Linoleylcarnitine	8770000.00	7740000.00	10200000.00	8930000.00	4160000.00	4870000.00	3180000.00	7640000.00	4830000.00	5980000.00	7220000.00	6610000.00	9840000.00	5140000.00	3850000.00	6280000.00	3380000.00	5520000.00	7110000.00	6600000.00	6060000.00	5870000.00	4750000.00	16000000.00	8910000.00	9620000.00	9200000.00	8120000.00	6610000.00	26200000.00	6930000.00	4540000.00	14300000.00
Cysteamine	3040000.00	3510000.00	3110000.00	3360000.00	3270000.00	3550000.00	3430000.00	3190000.00	3320000.00	2830000.00	3010000.00	3410000.00	2990000.00	3230000.00	3390000.00	3260000.00	3660000.00	3490000.00	3350000.00	2800000.00	3660000.00	3260000.00	3380000.00	2880000.00	4210000.00	2910000.00	3330000.00	2960000.00	3200000.00	3360000.00	3370000.00	3550000.00	3220000.00
Urea	38000000.00	39200000.00	40100000.00	42700000.00	41600000.00	45500000.00	45500000.00	43100000.00	41500000.00	36900000.00	41700000.00	41400000.00	36600000.00	42800000.00	44400000.00	43000000.00	43600000.00	47100000.00	47700000.00	33100000.00	49600000.00	45300000.00	45200000.00	40100000.00	44600000.00	44800000.00	44500000.00	41200000.00	46800000.00	46300000.00	44400000.00	45700000.00	42400000.00
Nicotinamide N-oxide	21700000.00	28800000.00	25100000.00	19000000.00	18800000.00	21800000.00	16800000.00	20700000.00	20700000.00	19100000.00	21100000.00	26100000.00	25500000.00	22400000.00	24400000.00	22700000.00	22800000.00	30700000.00	27900000.00	15900000.00	26800000.00	23600000.00	29300000.00	27700000.00	20700000.00	24900000.00	21900000.00	23900000.00	25300000.00	24300000.00	31600000.00	23800000.00	24700000.00
Isovalerylcarnitine	62000000.00	78700000.00	58900000.00	50000000.00	73600000.00	75200000.00	70900000.00	96300000.00	45800000.00	79500000.00	102000000.00	62700000.00	109000000.00	53200000.00	63400000.00	63900000.00	46800000.00	76600000.00	69600000.00	40200000.00	73500000.00	61200000.00	28600000.00	54800000.00	52300000.00	49700000.00	44700000.00	30900000.00	56700000.00	134000000.00	55800000.00	51300000.00	47900000.00
Dihexosylcer(18:1/16:0)	76900.00	66300.00	164000.00	135000.00	83900.00	100000.00	115000.00	79300.00	239000.00	114000.00	105000.00	211000.00	104000.00	83500.00	183000.00	134000.00	187000.00	260000.00	227000.00	75200.00	94500.00	161000.00	240000.00	95500.00	147000.00	127000.00	130000.00	128000.00	160000.00	132000.00	91800.00	102000.00	264000.00
Dihexosylcer(18:1/24:1)	22900.00	5680.00	24300.00	13300.00	14600.00	14300.00	11300.00	9400.00	23600.00	19600.00	13700.00	16100.00	11900.00	10900.00	18500.00	18100.00	20600.00	44500.00	20600.00	18600.00	16300.00	39500.00	32600.00	18400.00	21300.00	14800.00	14000.00	19900.00	16300.00	20500.00	13300.00	19100.00	31900.00
Butyrylcarnitine	19600000.00	22700000.00	14900000.00	14500000.00	20800000.00	25900000.00	23600000.00	27700000.00	17600000.00	20300000.00	19400000.00	17400000.00	25400000.00	22600000.00	20400000.00	23000000.00	14900000.00	19100000.00	20600000.00	145000000.00	27200000.00	19400000.00	13200000.00	24300000.00	29100000.00	14700000.00	15900000.00	13300000.00	20300000.00	48400000.00	16900000.00	17400000.00	21100000.00
Trimethylamine-N-oxide	130000000.00	130000000.00	102000000.00	120000000.00	195000000.00	154000000.00	135000000.00	132000000.00	156000000.00	142000000.00	134000000.00	160000000.00	139000000.00	157000000.00	152000000.00	178000000.00	169000000.00	194000000.00	38500000.00	111000000.00	215000000.00	121000000.00	212000000.00	43400000.00	178000000.00	24300000.00	60500000.00	68500000.00	46000000.00	104000000.00	133000000.00	195000000.00	157000000.00
Thiamine	230000.00	370000.00	224000.00	310000.00	144000.00	468000.00	132000.00	292000.00	910000.00	350000.00	133000.00	494000.00	668000.00	265000.00	625000.00	886000.00	359000.00	468000.00	557000.00	102000.00	315000.00	212000.00	412000.00	280000.00	80800.00	198000.00	230000.00	372000.00	301000.00	128000.00	1360000.00	529000.00	414000.00
Propionylcarnitine	50500000.00	55400000.00	46100000.00	49500000.00	53900000.00	89700000.00	65700000.00	58300000.00	84100000.00	60000000.00	56700000.00	61200000.00	78400000.00	51900000.00	67400000.00	64700000.00	84100000.00	55700000.00	79700000.00	80300000.00	70300000.00	68100000.00	48000000.00	53600000.00	72000000.00	60200000.00	48800000.00	45900000.00	53500000.00	94700000.00	42100000.00	56200000.00	42700000.00
Trihexosylcer(18:1/16:0)	23100.00	19700.00	39900.00	29500.00	40300.00	30200.00	47200.00	16200.00	35700.00	43400.00	31900.00	58300.00	21900.00	35000.00	31000.00	38800.00	41800.00	62300.00	36000.00	19900.00	28900.00	48100.00	66500.00	35000.00	36800.00	59500.00	40900.00	47900.00	35100.00	45200.00	32900.00	43800.00	48800.00
Histamine	80700000.00	79400000.00	79600000.00	81700000.00	82000000.00	77800000.00	83000000.00	81600000.00	90000000.00	84100000.00	93500000.00	90800000.00	86500000.00	95800000.00	87800000.00	96200000.00	98000000.00	87500000.00	88400000.00	35200000.00	95700000.00	91500000.00	86600000.00	97100000.00	80100000.00	105000000.00	79500000.00	101000000.00	94900000.00	105000000.00	96600000.00	101000000.00	91400000.00
L-Histidinol	106000.00	129000.00	332000.00	160000.00	270000.00	163000.00	120000.00	162000.00	236000.00	149000.00	523000.00	393000.00	74000.00	357000.00	163000.00	171000.00	348000.00	141000.00	223000.00	144000.00	138000.00	131000.00	242000.00	146000.00	288000.00	231000.00	125000.00	368000.00	124000.00	136000.00	143000.00	180000.00	164000.00
L-Acetylcarnitine	142000000.00	171000000.00	173000000.00	169000000.00	164000000.00	164000000.00	147000000.00	170000000.00	167000000.00	170000000.00	161000000.00	173000000.00	172000000.00	165000000.00	166000000.00	169000000.00	166000000.00	159000000.00	174000000.00	177000000.00	180000000.00	166000000.00	165000000.00	167000000.00	168000000.00	163000000.00	164000000.00	168000000.00	168000000.00	221000000.00	166000000.00	166000000.00	162000000.00
Cytosine	129000000.00	126000000.00	129000000.00	131000000.00	134000000.00	126000000.00	135000000.00	132000000.00	149000000.00	136000000.00	146000000.00	149000000.00	143000000.00	157000000.00	145000000.00	157000000.00	161000000.00	144000000.00	147000000.00	58700000.00	156000000.00	154000000.00	140000000.00	163000000.00	132000000.00	168000000.00	130000000.00	166000000.00	155000000.00	171000000.00	158000000.00	163000000.00	148000000.00
1-Methyladenosine	6150000.00	4950000.00	4710000.00	4910000.00	4860000.00	4960000.00	4880000.00	4520000.00	6240000.00	4960000.00	4580000.00	6470000.00	6060000.00	6550000.00	6280000.00	6500000.00	6850000.00	5080000.00	5850000.00	1560000.00	6540000.00	5830000.00	6190000.00	6170000.00	5730000.00	6460000.00	6390000.00	6700000.00	4980000.00	5540000.00	8420000.00	5630000.00	6220000.00
3-Hydroxyisovaleryl Carnitine	28400000.00	24300000.00	20000000.00	29300000.00	21200000.00	22400000.00	17900000.00	21200000.00	18500000.00	27200000.00	20300000.00	25600000.00	23800000.00	13800000.00	22400000.00	25000000.00	19900000.00	22800000.00	24100000.00	8400000.00	22500000.00	20200000.00	20100000.00	23300000.00	21400000.00	25600000.00	18700000.00	13500000.00	20000000.00	35700000.00	19800000.00	17900000.00	21100000.00
Adenosine	21900000.00	6040000.00	27800000.00	9530000.00	7610000.00	24600000.00	32100000.00	20900000.00	34600000.00	6800000.00	27000000.00	22800000.00	25100000.00	9510000.00	17400000.00	5340000.00	36500000.00	20400000.00	19600000.00	5270000.00	31800000.00	28100000.00	30600000.00	4950000.00	4060000.00	19500000.00	13200000.00	17000000.00	6160000.00	18700000.00	6310000.00	16600000.00	23000000.00
Riboflavin	25400.00	49100.00	45600.00	49900.00	28700.00	42700.00	27200.00	35400.00	103000.00	101000.00	113000.00	158000.00	84900.00	148000.00	68400.00	134000.00	69200.00	133000.00	140000.00	41000.00	133000.00	88300.00	126000.00	62100.00	77100.00	120000.00	90100.00	131000.00	83700.00	141000.00	60500.00	91100.00	120000.00
Normetanephrine	1800000.00	1960000.00	1350000.00	1900000.00	2120000.00	1530000.00	1920000.00	1640000.00	2080000.00	2030000.00	1870000.00	1990000.00	1660000.00	1870000.00	2440000.00	2590000.00	1760000.00	2280000.00	1910000.00	1110000.00	2360000.00	2060000.00	3080000.00	3300000.00	1960000.00	1500000.00	1450000.00	2240000.00	1670000.00	1410000.00	3460000.00	2270000.00	2680000.00
Hydroxykynurenine	814000.00	803000.00	807000.00	904000.00	979000.00	906000.00	951000.00	924000.00	1220000.00	1190000.00	1200000.00	1150000.00	1110000.00	1010000.00	1130000.00	1340000.00	1080000.00	1040000.00	977000.00	561000.00	1220000.00	1220000.00	1440000.00	1260000.00	757000.00	1180000.00	943000.00	1100000.00	972000.00	1270000.00	1150000.00	1130000.00	1000000.00
Ethanolamine	3750000.00	3410000.00	3520000.00	3990000.00	3970000.00	3920000.00	3650000.00	3480000.00	3970000.00	4570000.00	3470000.00	2000000.00	3240000.00	3520000.00	3740000.00	3900000.00	3750000.00	4930000.00	3980000.00	2760000.00	4410000.00	3730000.00	2420000.00	4040000.00	3960000.00	3990000.00	4190000.00	3770000.00	3510000.00	3120000.00	5400000.00	3950000.00	3050000.00
Malonylcarnitine	21500000.00	15700000.00	12800000.00	21300000.00	8880000.00	12700000.00	7850000.00	9050000.00	14000000.00	13100000.00	6250000.00	14700000.00	21600000.00	4520000.00	12900000.00	17400000.00	7360000.00	9980000.00	20900000.00	12500000.00	16700000.00	10300000.00	14400000.00	11100000.00	14500000.00	15800000.00	12100000.00	10700000.00	12800000.00	30300000.00	14700000.00	12400000.00	21800000.00
Cytidine	32200000.00	21800000.00	16000000.00	25800000.00	12600000.00	15000000.00	12300000.00	18700000.00	27400000.00	23500000.00	30800000.00	30700000.00	39300000.00	26400000.00	23100000.00	33900000.00	27000000.00	26900000.00	25400000.00	3630000.00	21600000.00	18300000.00	19600000.00	28000000.00	19200000.00	37500000.00	23600000.00	31800000.00	31600000.00	45100000.00	35200000.00	25100000.00	29200000.00
Adenine	1670000.00	874000.00	1880000.00	1160000.00	1820000.00	1760000.00	1990000.00	1420000.00	1810000.00	1080000.00	2040000.00	1370000.00	1560000.00	1470000.00	1420000.00	1050000.00	2110000.00	2170000.00	1360000.00	537000.00	1870000.00	1660000.00	1940000.00	1230000.00	1330000.00	1640000.00	1560000.00	1440000.00	1240000.00	1510000.00	1160000.00	1330000.00	1500000.00
L-Phenylalanine	30600000.00	35300000.00	34800000.00	37200000.00	33800000.00	33800000.00	42100000.00	41400000.00	35400000.00	40100000.00	34000000.00	53200000.00	40300000.00	34800000.00	39700000.00	39800000.00	36000000.00	58900000.00	41000000.00	15500000.00	37000000.00	35500000.00	35800000.00	35900000.00	33000000.00	34900000.00	38700000.00	38600000.00	34300000.00	42800000.00	40300000.00	36200000.00	40300000.00
L-leucine	157000000.00	162000000.00	157000000.00	161000000.00	167000000.00	163000000.00	176000000.00	186000000.00	188000000.00	184000000.00	162000000.00	229000000.00	185000000.00	174000000.00	182000000.00	186000000.00	183000000.00	220000000.00	195000000.00	84600000.00	162000000.00	156000000.00	178000000.00	157000000.00	164000000.00	170000000.00	164000000.00	183000000.00	152000000.00	192000000.00	180000000.00	171000000.00	179000000.00
Dimethylglycine	89200000.00	84200000.00	99400000.00	93000000.00	95100000.00	96400000.00	85300000.00	108000000.00	105000000.00	102000000.00	94400000.00	99400000.00	109000000.00	123000000.00	122000000.00	115000000.00	121000000.00	99300000.00	104000000.00	78900000.00	102000000.00	97300000.00	103000000.00	115000000.00	96200000.00	109000000.00	98100000.00	106000000.00	84500000.00	103000000.00	115000000.00	112000000.00	94500000.00
Purine	577000.00	583000.00	577000.00	576000.00	644000.00	475000.00	727000.00	695000.00	711000.00	747000.00	564000.00	1010000.00	673000.00	573000.00	676000.00	738000.00	604000.00	1030000.00	706000.00	169000.00	621000.00	645000.00	577000.00	652000.00	510000.00	593000.00	617000.00	564000.00	601000.00	748000.00	700000.00	602000.00	704000.00
3-Hydroxydodecanoylcarnitine	618000.00	537000.00	482000.00	792000.00	590000.00	1550000.00	632000.00	444000.00	641000.00	574000.00	756000.00	562000.00	771000.00	667000.00	709000.00	668000.00	792000.00	696000.00	715000.00	2290000.00	690000.00	619000.00	778000.00	638000.00	641000.00	1020000.00	753000.00	743000.00	577000.00	691000.00	697000.00	649000.00	694000.00
Acetylcholine	47600000.00	43100000.00	46300000.00	51100000.00	43300000.00	49800000.00	53600000.00	49800000.00	54600000.00	56600000.00	52700000.00	57900000.00	49200000.00	53200000.00	53800000.00	60300000.00	44100000.00	53900000.00	48300000.00	29300000.00	60900000.00	57400000.00	63300000.00	49600000.00	47900000.00	76300000.00	60100000.00	69800000.00	62900000.00	83300000.00	63600000.00	57600000.00	64700000.00
L-Carnitine	23500000.00	24500000.00	24500000.00	23600000.00	22800000.00	24000000.00	22600000.00	24600000.00	21700000.00	25300000.00	27800000.00	23400000.00	26400000.00	20800000.00	22800000.00	24900000.00	19300000.00	26900000.00	22800000.00	20000000.00	25000000.00	26000000.00	19700000.00	25400000.00	22100000.00	25000000.00	21300000.00	19700000.00	21900000.00	28900000.00	20800000.00	21900000.00	21700000.00
L-Methionine	17200000.00	19700000.00	18100000.00	21300000.00	19900000.00	21200000.00	20100000.00	22500000.00	22400000.00	23300000.00	15600000.00	29500000.00	26500000.00	16500000.00	22600000.00	23900000.00	19000000.00	32900000.00	26000000.00	11600000.00	21500000.00	17700000.00	20900000.00	21100000.00	18900000.00	23500000.00	25500000.00	27900000.00	21800000.00	21400000.00	26300000.00	24000000.00	25600000.00
L-Valine	888000.00	976000.00	987000.00	969000.00	1250000.00	1180000.00	1300000.00	1270000.00	1640000.00	1460000.00	1070000.00	1940000.00	1470000.00	1380000.00	1500000.00	1450000.00	1320000.00	2030000.00	1670000.00	542000.00	1320000.00	1060000.00	1440000.00	1020000.00	1140000.00	1260000.00	1170000.00	1400000.00	973000.00	1290000.00	1330000.00	1120000.00	1250000.00
Biotin	1640000.00	1500000.00	1280000.00	1120000.00	1350000.00	1050000.00	1230000.00	1140000.00	864000.00	1040000.00	976000.00	872000.00	1170000.00	967000.00	1000000.00	1190000.00	1180000.00	1040000.00	1090000.00	887000.00	955000.00	993000.00	901000.00	1010000.00	1430000.00	959000.00	1320000.00	1240000.00	1050000.00	979000.00	1090000.00	929000.00	1180000.00
Metanephrine	969000.00	1220000.00	772000.00	1030000.00	1020000.00	914000.00	832000.00	877000.00	1060000.00	946000.00	1120000.00	584000.00	678000.00	1230000.00	874000.00	953000.00	1950000.00	1160000.00	1210000.00	1980000.00	983000.00	960000.00	822000.00	1320000.00	1340000.00	1300000.00	1150000.00	945000.00	1170000.00	1270000.00	1180000.00	1250000.00	1080000.00
Glycerophosphocholine	39200000.00	31600000.00	39200000.00	32000000.00	84700000.00	38600000.00	60300000.00	35500000.00	18100000.00	46700000.00	83500000.00	24800000.00	26500000.00	75000000.00	21200000.00	20800000.00	28900000.00	37200000.00	22700000.00	37900000.00	32500000.00	29700000.00	27100000.00	56100000.00	51500000.00	27500000.00	40300000.00	34500000.00	31500000.00	43100000.00	28200000.00	27000000.00	26800000.00
1-Methylhistidine	5040000.00	4230000.00	5300000.00	5680000.00	4970000.00	3850000.00	6320000.00	5380000.00	5150000.00	4160000.00	5180000.00	6050000.00	5560000.00	5230000.00	4440000.00	6230000.00	4010000.00	9720000.00	6090000.00	6330000.00	6040000.00	6630000.00	7020000.00	6400000.00	5730000.00	7410000.00	7530000.00	8520000.00	6140000.00	8230000.00	8850000.00	6760000.00	8140000.00
L-Tryptophan	53600000.00	32400000.00	28000000.00	57300000.00	54600000.00	57100000.00	63100000.00	62800000.00	61600000.00	69000000.00	49600000.00	95100000.00	85100000.00	41400000.00	68800000.00	69300000.00	40000000.00	62800000.00	64500000.00	39700000.00	59200000.00	57600000.00	44600000.00	49500000.00	51800000.00	56400000.00	54200000.00	48700000.00	58400000.00	84000000.00	61700000.00	67800000.00	65700000.00
Suberylcarnitine	2010000.00	1910000.00	2150000.00	2010000.00	2220000.00	2070000.00	2200000.00	2240000.00	2760000.00	2840000.00	2360000.00	2400000.00	2470000.00	2580000.00	2380000.00	2720000.00	2800000.00	1640000.00	2840000.00	4610000.00	2350000.00	2380000.00	2790000.00	2590000.00	2360000.00	3210000.00	3010000.00	3270000.00	2040000.00	2800000.00	2450000.00	2270000.00	2610000.00
Norepinephrine	112000.00	124000.00	149000.00	274000.00	137000.00	135000.00	124000.00	130000.00	132000.00	228000.00	159000.00	283000.00	174000.00	162000.00	171000.00	171000.00	174000.00	144000.00	154000.00	146000.00	245000.00	174000.00	326000.00	159000.00	213000.00	158000.00	167000.00	133000.00	220000.00	131000.00	187000.00	209000.00	127000.00
Indole	1320000.00	1520000.00	1130000.00	1800000.00	1780000.00	1740000.00	1900000.00	1840000.00	1920000.00	2030000.00	1670000.00	3100000.00	1800000.00	1110000.00	2120000.00	2160000.00	1210000.00	1950000.00	1560000.00	908000.00	1720000.00	1730000.00	1260000.00	1380000.00	1300000.00	1330000.00	1560000.00	1560000.00	1800000.00	1870000.00	2220000.00	2070000.00	2170000.00
Methionine sulfoxide	299000.00	261000.00	325000.00	306000.00	382000.00	383000.00	551000.00	545000.00	380000.00	418000.00	516000.00	464000.00	245000.00	425000.00	318000.00	406000.00	513000.00	1140000.00	468000.00	336000.00	523000.00	526000.00	492000.00	371000.00	294000.00	381000.00	438000.00	339000.00	320000.00	719000.00	422000.00	376000.00	242000.00
Alanine	24200000.00	25900000.00	26000000.00	29000000.00	30400000.00	34500000.00	26800000.00	22300000.00	33100000.00	30900000.00	22400000.00	29500000.00	30500000.00	19300000.00	30000000.00	30300000.00	27000000.00	40500000.00	35900000.00	38700000.00	36600000.00	32100000.00	37700000.00	29200000.00	30000000.00	43500000.00	41000000.00	34200000.00	32800000.00	35700000.00	44300000.00	36800000.00	41800000.00
Sarcosine	30800000.00	32900000.00	32600000.00	35400000.00	36300000.00	40700000.00	32300000.00	27900000.00	41000000.00	39500000.00	29300000.00	35600000.00	35000000.00	24500000.00	36600000.00	36700000.00	34300000.00	49700000.00	43000000.00	45200000.00	41500000.00	39800000.00	46100000.00	34100000.00	37100000.00	51800000.00	50100000.00	42600000.00	39100000.00	41400000.00	51800000.00	44700000.00	50800000.00
L-Glutarylcarnitine	1500000.00	1530000.00	1250000.00	1530000.00	1350000.00	1220000.00	1350000.00	1460000.00	1340000.00	1660000.00	1980000.00	1400000.00	1600000.00	1400000.00	1470000.00	1770000.00	1960000.00	1490000.00	2080000.00	6320000.00	1550000.00	1560000.00	1460000.00	1660000.00	2060000.00	1730000.00	2220000.00	1580000.00	1450000.00	2170000.00	2060000.00	1730000.00	1560000.00
Serotonin	859000.00	680000.00	840000.00	836000.00	477000.00	1210000.00	1260000.00	828000.00	1960000.00	550000.00	1310000.00	1210000.00	1370000.00	530000.00	1320000.00	1320000.00	2160000.00	305000.00	361000.00	265000.00	414000.00	402000.00	369000.00	289000.00	125000.00	2070000.00	1200000.00	2540000.00	378000.00	1700000.00	917000.00	1420000.00	1360000.00
Gamma-Aminobutyric acid	22000.00	24000.00	29400.00	20300.00	30600.00	27300.00	24100.00	22500.00	61500.00	32300.00	18500.00	27400.00	30000.00	38300.00	13800.00	24000.00	38700.00	38000.00	43300.00	22200.00	48700.00	17900.00	128000.00	33400.00	10300.00	31900.00	57000.00	41800.00	43600.00	33700.00	39100.00	35200.00	26500.00
L-Asparagine	847000.00	946000.00	794000.00	798000.00	1050000.00	984000.00	912000.00	1180000.00	1280000.00	1370000.00	792000.00	1120000.00	1260000.00	1030000.00	974000.00	968000.00	1030000.00	1520000.00	1610000.00	383000.00	1210000.00	998000.00	1390000.00	872000.00	620000.00	1130000.00	1020000.00	1220000.00	768000.00	1180000.00	1040000.00	905000.00	1130000.00
L-Glutamine	152000000.00	151000000.00	145000000.00	136000000.00	151000000.00	137000000.00	145000000.00	146000000.00	161000000.00	158000000.00	145000000.00	176000000.00	167000000.00	144000000.00	163000000.00	160000000.00	149000000.00	166000000.00	154000000.00	174000000.00	150000000.00	151000000.00	165000000.00	144000000.00	142000000.00	148000000.00	155000000.00	157000000.00	132000000.00	155000000.00	156000000.00	148000000.00	152000000.00
Pipecolic acid	121000000.00	108000000.00	117000000.00	128000000.00	130000000.00	123000000.00	123000000.00	126000000.00	148000000.00	131000000.00	132000000.00	156000000.00	129000000.00	133000000.00	141000000.00	147000000.00	130000000.00	159000000.00	145000000.00	45900000.00	136000000.00	141000000.00	164000000.00	143000000.00	102000000.00	133000000.00	135000000.00	153000000.00	105000000.00	139000000.00	142000000.00	136000000.00	140000000.00
Cysteine	77100.00	73500.00	76800.00	85200.00	72600.00	77900.00	84200.00	76600.00	92800.00	108000.00	106000.00	96900.00	78000.00	105000.00	86800.00	104000.00	84500.00	72900.00	75000.00	77500.00	106000.00	93800.00	105000.00	72800.00	77100.00	91900.00	78000.00	129000.00	94200.00	94200.00	92300.00	90900.00	72100.00
S-Adenosylmethionine	10500.00	5450.00	5360.00	7240.00	4490.00	5830.00	3670.00	5000.00	6530.00	10200.00	5240.00	9160.00	6720.00	6780.00	6380.00	7390.00	7250.00	2980.00	10500.00	13100.00	6330.00	4080.00	4700.00	9300.00	6190.00	5110.00	5130.00	5950.00	4280.00	6540.00	12300.00	8670.00	3670.00
L-Serine	4070000.00	5100000.00	5320000.00	4960000.00	5520000.00	4620000.00	4690000.00	6400000.00	5970000.00	5700000.00	3990000.00	6220000.00	4830000.00	4300000.00	4500000.00	4960000.00	4250000.00	7020000.00	6780000.00	2410000.00	5750000.00	4310000.00	6410000.00	4630000.00	3260000.00	5700000.00	5210000.00	5280000.00	3080000.00	6510000.00	5390000.00	4270000.00	4510000.00
L-Tyrosine	937000.00	938000.00	1070000.00	1210000.00	775000.00	872000.00	1230000.00	1330000.00	1640000.00	1510000.00	909000.00	2020000.00	1680000.00	1190000.00	1590000.00	1320000.00	1020000.00	2020000.00	1190000.00	951000.00	1020000.00	1290000.00	1450000.00	985000.00	918000.00	1330000.00	1280000.00	1650000.00	1140000.00	1750000.00	2250000.00	1250000.00	1590000.00
Phosphorylcholine	1860000.00	1800000.00	1280000.00	1850000.00	1530000.00	2140000.00	1150000.00	1310000.00	3590000.00	1980000.00	2360000.00	3780000.00	2630000.00	1470000.00	2160000.00	3870000.00	3330000.00	3150000.00	4680000.00	2050000.00	2090000.00	2630000.00	3050000.00	2490000.00	2080000.00	4300000.00	2500000.00	5470000.00	1410000.00	4020000.00	2300000.00	3560000.00	2810000.00
Ornithine	82600.00	91800.00	147000.00	223000.00	155000.00	135000.00	124000.00	153000.00	154000.00	198000.00	92500.00	217000.00	152000.00	92300.00	128000.00	186000.00	94100.00	359000.00	184000.00	156000.00	138000.00	106000.00	144000.00	106000.00	88800.00	219000.00	92500.00	136000.00	87900.00	115000.00	183000.00	111000.00	177000.00
L-Kynurenine	316000.00	307000.00	265000.00	288000.00	274000.00	518000.00	333000.00	339000.00	324000.00	417000.00	330000.00	544000.00	547000.00	269000.00	414000.00	458000.00	345000.00	470000.00	306000.00	130000.00	282000.00	286000.00	325000.00	372000.00	310000.00	423000.00	288000.00	339000.00	393000.00	429000.00	1670000.00	293000.00	872000.00
Glycine	303000.00	293000.00	352000.00	296000.00	333000.00	357000.00	320000.00	381000.00	380000.00	353000.00	288000.00	485000.00	374000.00	393000.00	320000.00	379000.00	283000.00	496000.00	319000.00	223000.00	452000.00	318000.00	470000.00	327000.00	284000.00	408000.00	460000.00	442000.00	258000.00	331000.00	363000.00	291000.00	405000.00
Carnosine	917000.00	1080000.00	822000.00	1030000.00	1950000.00	1290000.00	177000.00	302000.00	1110000.00	1450000.00	371000.00	545000.00	434000.00	162000.00	593000.00	714000.00	370000.00	537000.00	1380000.00	415000.00	1920000.00	1010000.00	2240000.00	728000.00	697000.00	830000.00	992000.00	836000.00	1000000.00	349000.00	1010000.00	737000.00	1360000.00
Histidine	5960000.00	5450000.00	6790000.00	6690000.00	7470000.00	6760000.00	7240000.00	7140000.00	10500000.00	8770000.00	6630000.00	10100000.00	8510000.00	8250000.00	7170000.00	9150000.00	6900000.00	10200000.00	9110000.00	3010000.00	8920000.00	7650000.00	11000000.00	7070000.00	4900000.00	10200000.00	7010000.00	9850000.00	6450000.00	9760000.00	9190000.00	7780000.00	8390000.00
Lysine	116000000.00	114000000.00	118000000.00	115000000.00	122000000.00	114000000.00	118000000.00	121000000.00	143000000.00	141000000.00	117000000.00	158000000.00	142000000.00	123000000.00	143000000.00	138000000.00	124000000.00	151000000.00	134000000.00	94300000.00	128000000.00	130000000.00	145000000.00	121000000.00	108000000.00	118000000.00	121000000.00	135000000.00	108000000.00	125000000.00	134000000.00	129000000.00	130000000.00
Saccharopine	510000.00	447000.00	478000.00	510000.00	548000.00	509000.00	504000.00	494000.00	610000.00	600000.00	516000.00	712000.00	638000.00	489000.00	708000.00	656000.00	471000.00	1350000.00	531000.00	1390000.00	528000.00	519000.00	788000.00	489000.00	457000.00	563000.00	562000.00	572000.00	461000.00	485000.00	775000.00	530000.00	677000.00
Dopamine	318000.00	208000.00	255000.00	233000.00	247000.00	273000.00	261000.00	287000.00	191000.00	185000.00	443000.00	245000.00	266000.00	277000.00	570000.00	230000.00	273000.00	340000.00	274000.00	378000.00	301000.00	381000.00	462000.00	228000.00	296000.00	285000.00	247000.00	204000.00	446000.00	261000.00	298000.00	226000.00	196000.00
Spermidine	139000.00	80800.00	128000.00	118000.00	171000.00	166000.00	167000.00	133000.00	121000.00	129000.00	172000.00	135000.00	155000.00	132000.00	160000.00	135000.00	141000.00	136000.00	125000.00	63300.00	141000.00	146000.00	118000.00	150000.00	137000.00	115000.00	142000.00	66400.00	105000.00	132000.00	146000.00	148000.00	137000.00
L-Glutamic acid	3590000.00	4430000.00	4700000.00	4380000.00	5060000.00	4890000.00	4730000.00	5490000.00	8020000.00	5950000.00	5380000.00	9000000.00	7360000.00	4420000.00	5820000.00	7530000.00	5410000.00	7970000.00	5900000.00	2590000.00	5610000.00	5200000.00	6680000.00	3430000.00	3720000.00	6450000.00	4820000.00	6400000.00	5030000.00	11600000.00	8040000.00	7540000.00	5910000.00
8-Hydroxy-deoxyguanosine	72500.00	72200.00	58700.00	67800.00	73500.00	53700.00	64700.00	44500.00	74800.00	78900.00	58700.00	82100.00	98700.00	68500.00	87000.00	76500.00	113000.00	86000.00	82000.00	324000.00	156000.00	57300.00	87400.00	65000.00	83100.00	81700.00	119000.00	73600.00	66100.00	41600.00	133000.00	104000.00	80900.00
Oxidized glutathione	7400.00	8000.00	9730.00	5740.00	8110.00	7800.00	3420.00	6100.00	17200.00	16500.00	3790.00	16700.00	8420.00	3390.00	15400.00	18000.00	5990.00	12300.00	22200.00	16800.00	10900.00	5940.00	11000.00	6170.00	8570.00	6620.00	5290.00	7890.00	8920.00	4580.00	1790.00	5460.00	14800.00
Epinephrine	281000.00	347000.00	340000.00	269000.00	353000.00	307000.00	255000.00	345000.00	283000.00	393000.00	299000.00	341000.00	277000.00	290000.00	282000.00	319000.00	281000.00	362000.00	323000.00	134000.00	429000.00	311000.00	283000.00	355000.00	369000.00	224000.00	275000.00	292000.00	296000.00	447000.00	339000.00	265000.00	283000.00
5-Hydroxyindoleacetic acid	2860000.00	4060000.00	2710000.00	4720000.00	4380000.00	3060000.00	3040000.00	2200000.00	3620000.00	3950000.00	2530000.00	5430000.00	6360000.00	1780000.00	4700000.00	5530000.00	2070000.00	3410000.00	7900000.00	3600000.00	4060000.00	3000000.00	4310000.00	3330000.00	3420000.00	4400000.00	2040000.00	11100000.00	3710000.00	2010000.00	5900000.00	30400000.00	3660000.00
Adenosine monophosphate	1270000.00	1210000.00	1570000.00	1100000.00	1050000.00	2890000.00	2720000.00	2090000.00	3940000.00	496000.00	1770000.00	1970000.00	1830000.00	389000.00	2190000.00	2860000.00	5810000.00	1280000.00	1340000.00	1470000.00	1130000.00	2780000.00	1380000.00	558000.00	450000.00	4630000.00	1850000.00	5360000.00	769000.00	2320000.00	1270000.00	1180000.00	922000.00
5-Methyltetrahydrofolic acid	19800.00	22300.00	4860.00	37400.00	32200.00	20600.00	5470.00	2800.00	48100.00	41200.00	5780.00	63300.00	109000.00	28600.00	56300.00	60400.00	21600.00	4910.00	132000.00	59000.00	39300.00	13300.00	72100.00	36400.00	18000.00	61200.00	19700.00	54100.00	16500.00	30900.00	113000.00	47900.00	60200.00
Cysteine-S-sulfate	90300.00	50900.00	51700.00	97800.00	173000.00	38300.00	155000.00	139000.00	25800.00	15500.00	45400.00	55100.00	13700.00	41800.00	29800.00	35200.00	83200.00	92100.00	19600.00	4160.00	124000.00	64000.00	114000.00	95500.00	67900.00	74800.00	180000.00	76900.00	44000.00	81100.00	66100.00	35300.00	35600.00
Cortisol	69300.00	65500.00	63600.00	65500.00	36500.00	67700.00	40000.00	72200.00	73100.00	75500.00	85000.00	74800.00	71200.00	41400.00	53900.00	32000.00	65100.00	50900.00	58300.00	78600.00	72200.00	72700.00	68700.00	84700.00	99600.00	25500.00	90500.00	27300.00	99000.00	28400.00	79000.00	71100.00	37000.00
Hypotaurine	19100.00	38100.00	22200.00	24100.00	50900.00	31100.00	26500.00	21600.00	58900.00	56100.00	33600.00	34000.00	40300.00	28300.00	50000.00	53100.00	46900.00	42300.00	66400.00	367000.00	55100.00	33300.00	40700.00	33400.00	16800.00	55700.00	50800.00	49500.00	29200.00	25000.00	79400.00	33800.00	44000.00
1-Methyladenine	73000.00	93300.00	92600.00	85300.00	145000.00	73400.00	65100.00	85700.00	68400.00	70800.00	98900.00	91100.00	74300.00	190000.00	122000.00	86700.00	151000.00	65100.00	49500.00	21300.00	109000.00	113000.00	124000.00	121000.00	97300.00	128000.00	96900.00	116000.00	118000.00	75300.00	126000.00	113000.00	103000.00
N-alpha-Acetylarginine	623000.00	1070000.00	887000.00	1320000.00	962000.00	650000.00	1090000.00	802000.00	615000.00	562000.00	881000.00	759000.00	1300000.00	755000.00	801000.00	1640000.00	512000.00	2190000.00	1080000.00	181000.00	686000.00	995000.00	1420000.00	1710000.00	1160000.00	1570000.00	1770000.00	2150000.00	581000.00	2570000.00	2210000.00	1460000.00	3000000.00
Homoarginine	749000.00	746000.00	896000.00	1040000.00	873000.00	1040000.00	853000.00	905000.00	1190000.00	1230000.00	930000.00	1050000.00	770000.00	1140000.00	9510000.00	8570000.00	859000.00	1810000.00	976000.00	387000.00	1160000.00	950000.00	1310000.00	1230000.00	525000.00	1460000.00	1270000.00	1050000.00	803000.00	1590000.00	1550000.00	1220000.00	1090000.00
MS_METABOLITE_DATA_END
#METABOLITES
METABOLITES_START
metabolite_name	retention index	quantified m/z	PubChem ID	KEGG ID
Creatine			586	C00300
CoQ9			5280473	C01967
CoQ9H2			5154674
Retinol			445354	C00473
Alpha-Tocopherol			14985	C02477
Vitamin K2			5283547	C00828
Cholesterol			11025495	C00187
5,6-trans-25-Hydroxyvitamin D3			53477885
Retinal			638015	C00376
7-ketocholesterol			53477696
Cer(d18:1/22:0 OH)
Cer(d18:1/18:0)
Cer(d18:1/22:0)
Cer(d18:1/24:0)
Cer(d18:1/24:1)
Cer(d18:1/24:2)
Cer(d18:1/25:0)
Vitamin D3			10883523	C05443
Cer(d18:1/23:0)			52931115
N-oleoylethanolamine			5283454
2-Arachidonylglycerol			5282280	C13856
Testosterone			6013	C00535
PC(22:6/P-18:0)
PC(16:0/16:0)			452110	C00157
PC(16:0/18:1)			5497103	C00157
PC(18:0/18:2)			6441487	C00157
Corticosterone			5753	C02140
Choline			305	C00114
Melatonin			896	C01598
Niacinamide			936	C00153
PC(16:0/22:6)			6441886	C00157
PC(16:0/18:2)			5287971	C00157
PC(16:0/20:4)			10747814	C00157
PC(20:4/P-16:0)
Dodecenoylcarnitine
Glucosylceramide(18:1/16:0)
L-Palmitoylcarnitine			11953816	C02990
Oleoylcarnitine			53477789
Octadecanoylcarnitine			6426855
LysoPC(16:0)			460602	C04230
Dodecanoylcarnitine			168381
Myristoylcarnitine			53477791
Linoleylcarnitine			6437058
Cysteamine			6058	C01678
Urea			1176	C00086
Nicotinamide N-oxide			72661
Isovalerylcarnitine			6426851
Dihexosylcer(18:1/16:0)
Dihexosylcer(18:1/24:1)
Butyrylcarnitine			439829	C02862
Trimethylamine-N-oxide			1145	C01104
Thiamine			1130	C00378
Propionylcarnitine			107738	C03017
Trihexosylcer(18:1/16:0)
Histamine			774	C00388
L-Histidinol			165271	C00860
L-Acetylcarnitine			1	C02571
Cytosine			597	C00380
1-Methyladenosine			27476	C02494
3-Hydroxyisovaleryl Carnitine
Adenosine			60961	C00212
Riboflavin			493570	C00255
Normetanephrine			1237	C05589
Hydroxykynurenine			89	C02794
Ethanolamine			700	C00189
Malonylcarnitine			22833583
Cytidine			6175	C00475
Adenine			190	C00147
L-Phenylalanine			6140	C00079
L-leucine			6106	C00123
Dimethylglycine			673	C01026
Purine			1044	C15587
3-Hydroxydodecanoylcarnitine
Acetylcholine			187	C01996
L-Carnitine			2724480	C15025
L-Methionine			6137	C00073
L-Valine			6287	C00183
Biotin			171548	C00120
Metanephrine			21100	C05588
Glycerophosphocholine			71920	C00670
1-Methylhistidine			92105	C01152
L-Tryptophan			6305	C00078
Suberylcarnitine
Norepinephrine			439260	C00547
Indole			798	C00463
Methionine sulfoxide			847
Alanine			5950	C00041
Sarcosine			1088	C00213
L-Glutarylcarnitine
Serotonin			5202	C00780
Gamma-Aminobutyric acid			119	C00334
L-Asparagine			6267	C00152
L-Glutamine			5961	C00064
Pipecolic acid			849	C00408
Cysteine			5862	C00097
S-Adenosylmethionine			16757548	C00019
L-Serine			5951	C00065
L-Tyrosine			6057	C00082
Phosphorylcholine			1014	C00588
Ornithine			6262	C00077
L-Kynurenine			161166	C00328
Glycine			750	C00037
Carnosine			439224	C00386
Histidine			6274	C00135
Lysine			5962	C00047
Saccharopine			160556	C00449
Dopamine			681	C03758
Spermidine			1102	C00315
L-Glutamic acid			33032	C00025
8-Hydroxy-deoxyguanosine			73318
Oxidized glutathione			975	C00127
Epinephrine			5816	C00788
5-Hydroxyindoleacetic acid			1826	C05635
Adenosine monophosphate			6083	C00020
5-Methyltetrahydrofolic acid			439234	C00440
Cysteine-S-sulfate			115015	C05824
Cortisol			657311	C00735
Hypotaurine			107812	C00519
1-Methyladenine			78821	C02216
N-alpha-Acetylarginine			67249	C05904
Homoarginine			9085	C01924
METABOLITES_END
#END