#METABOLOMICS WORKBENCH bkopp20_20181010_103752 DATATRACK_ID:1538 VERSION 1 CREATED_ON January 7, 2019, 1:01 pm #PROJECT PR:PROJECT_TITLE Environmental exposures and inflammation in young children with cystic fibrosis PR:PROJECT_TYPE NIH/NIEHS 1U2CES026560-01 PR:PROJECT_SUMMARY Secondhand smoke exposure (SHSe) is a common environmental factor known to PR:PROJECT_SUMMARY increase asthma severity and respiratory infections in children, as well disrupt PR:PROJECT_SUMMARY metabolic signals and host immune responses in patients with cystic fibrosis PR:PROJECT_SUMMARY (CF). This study defines biomarkers and metabolic profiles of SHSe (includes PR:PROJECT_SUMMARY ENDS exposure) in the young CF population and determines how SHSe impacts PR:PROJECT_SUMMARY regulation of infection, inflammation, and respiratory health. PR:INSTITUTE Emory University PR:DEPARTMENT School of Medicine PR:LABORATORY Clinical Biomarkers Laboratory PR:LAST_NAME Ma PR:FIRST_NAME Chunyu PR:ADDRESS 615 Michael Street, Atlanta, GA, 30322, USA PR:EMAIL chunyu.ma@emory.edu PR:PHONE (404) 727 5091 PR:FUNDING_SOURCE NIEHS ES026560 PR:CONTRIBUTORS Benjamin Kopp, MD #STUDY ST:STUDY_TITLE Environmental exposures and inflammation in young children with cystic fibrosis ST:STUDY_TYPE Untargeted high-resolution mass spectrometry profiling ST:STUDY_SUMMARY Secondhand smoke exposure (SHSe) is a common environmental factor known to ST:STUDY_SUMMARY increase asthma severity and respiratory infections in children, as well disrupt ST:STUDY_SUMMARY metabolic signals and host immune responses in patients with cystic fibrosis ST:STUDY_SUMMARY (CF). This study defines biomarkers and metabolic profiles of SHSe (includes ST:STUDY_SUMMARY ENDS exposure) in the young CF population and determines how SHSe impacts ST:STUDY_SUMMARY regulation of infection, inflammation, and respiratory health. ST:INSTITUTE Emory University ST:DEPARTMENT School of Medicine ST:LABORATORY Clincal Biomarkers Laboratory ST:LAST_NAME Ma ST:FIRST_NAME Chunyu ST:ADDRESS 615 Michael St. Ste 225, Atlanta, GA, 30322, USA ST:EMAIL chunyu.ma@emory.edu ST:PHONE (404) 727 5091 ST:TOTAL_SUBJECTS 92 ST:STUDY_COMMENTS Both CHEAR and Clinical Biomarkers Laboratory pooled plasma samples were used ST:STUDY_COMMENTS for quality control. Study specific sample pools were not created #SUBJECT SU:SUBJECT_TYPE Plasma samples SU:SUBJECT_SPECIES Homo sapiens SU:TAXONOMY_ID 9606 SU:AGE_OR_AGE_RANGE 4 months - 10 years #SUBJECT_SAMPLE_FACTORS: SUBJECT(optional)[tab]SAMPLE[tab]FACTORS(NAME:VALUE pairs separated by |)[tab]Additional sample data SUBJECT_SAMPLE_FACTORS Quality Control NIST SRM 1950_1_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:- Sample Matrix=Plasma; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Plasma; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005" SUBJECT_SAMPLE_FACTORS Quality Control Q-Std Plasma pool_1a_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:- Sample Matrix=Plasma; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Plasma; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_007,VT_180710_M351_009,VT_180710_M351_011" SUBJECT_SAMPLE_FACTORS Serum Study Sample chearplasma_1a_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:- Sample Matrix=Serum; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_013,VT_180710_M351_015,VT_180710_M351_017" SUBJECT_SAMPLE_FACTORS Serum Study Sample chearplasma_1b_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:- Sample Matrix=Serum; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_019,VT_180710_M351_021,VT_180710_M351_023" SUBJECT_SAMPLE_FACTORS Serum Study Sample 3_Baseline_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_025,VT_180710_M351_027,VT_180710_M351_029" SUBJECT_SAMPLE_FACTORS Serum Study Sample 4_Baseline_1 INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:M Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_031,VT_180710_M351_033,VT_180710_M351_035" SUBJECT_SAMPLE_FACTORS Serum Study Sample 5_Baseline_1 INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_037,VT_180710_M351_039,VT_180710_M351_041" SUBJECT_SAMPLE_FACTORS Serum Study Sample 6_Baseline_1 INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:M Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_043,VT_180710_M351_045,VT_180710_M351_047" SUBJECT_SAMPLE_FACTORS Serum Study Sample 7_Baseline_1 INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_049,VT_180710_M351_051,VT_180710_M351_053" SUBJECT_SAMPLE_FACTORS Serum Study Sample 8_Baseline_1 INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_055,VT_180710_M351_057,VT_180710_M351_059" SUBJECT_SAMPLE_FACTORS Serum Study Sample 8_Visit_2_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=visit_2; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_061,VT_180710_M351_063,VT_180710_M351_065" SUBJECT_SAMPLE_FACTORS Serum Study Sample 9_Baseline_1 INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:M Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_067,VT_180710_M351_069,VT_180710_M351_071" SUBJECT_SAMPLE_FACTORS Serum Study Sample 10_Visit_2_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:M Sample Matrix=Serum; Event Name=visit_2; CF genotype=F508 del /1898+1G>A; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_073,VT_180710_M351_075,VT_180710_M351_077" SUBJECT_SAMPLE_FACTORS Serum Study Sample 10_Baseline_1 INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:M Sample Matrix=Serum; Event Name=baseline; CF genotype=F508 del /1898+1G>A; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_079,VT_180710_M351_081,VT_180710_M351_083" SUBJECT_SAMPLE_FACTORS Serum Study Sample 11_Baseline_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=baseline; CF genotype=R74Q/R297Q; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_085,VT_180710_M351_087,VT_180710_M351_089" SUBJECT_SAMPLE_FACTORS Serum Study Sample 12_Baseline_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=baseline; CF genotype=R74Q/R297Q; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_091,VT_180710_M351_093,VT_180710_M351_095" SUBJECT_SAMPLE_FACTORS Serum Study Sample 14_Baseline_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_097,VT_180710_M351_099,VT_180710_M351_101" SUBJECT_SAMPLE_FACTORS Serum Study Sample 15_Baseline_1 INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_103,VT_180710_M351_105,VT_180710_M351_107" SUBJECT_SAMPLE_FACTORS Serum Study Sample 23_Visit_2_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=visit_2; CF genotype=F508del/Unknown; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_109,VT_180710_M351_111,VT_180710_M351_113" SUBJECT_SAMPLE_FACTORS Serum Study Sample 25_Baseline_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:M Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_115,VT_180710_M351_117,VT_180710_M351_119" SUBJECT_SAMPLE_FACTORS Serum Study Sample 26_Baseline_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, CFTR del 2,3"; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_121,VT_180710_M351_123,VT_180710_M351_125" SUBJECT_SAMPLE_FACTORS Serum Study Sample 27_Baseline_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:M Sample Matrix=Serum; Event Name=baseline; CF genotype=Delta F 508/Q493X; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_127,VT_180710_M351_129,VT_180710_M351_131" SUBJECT_SAMPLE_FACTORS Serum Study Sample 28_Baseline_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=baseline; CF genotype=" F508del, 3849 + 10kb C>T"; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_133,VT_180710_M351_135,VT_180710_M351_137" SUBJECT_SAMPLE_FACTORS Serum Study Sample 29_Baseline_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/F508del; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_139,VT_180710_M351_141,VT_180710_M351_143" SUBJECT_SAMPLE_FACTORS Serum Study Sample chearplasma_1c_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:- Sample Matrix=Serum; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_145,VT_180710_M351_147,VT_180710_M351_149" SUBJECT_SAMPLE_FACTORS Serum Study Sample chearplasma_1d_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:- Sample Matrix=Serum; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_151,VT_180710_M351_153,VT_180710_M351_155" SUBJECT_SAMPLE_FACTORS Serum Study Sample 30_Baseline_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:M Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/F508del; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_157,VT_180710_M351_159,VT_180710_M351_161" SUBJECT_SAMPLE_FACTORS Serum Study Sample 31_Baseline_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:M Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/F508del; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_163,VT_180710_M351_165,VT_180710_M351_167" SUBJECT_SAMPLE_FACTORS Serum Study Sample 32_Baseline_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=baseline; CF genotype=R560T/R1158X; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_169,VT_180710_M351_171,VT_180710_M351_173" SUBJECT_SAMPLE_FACTORS Serum Study Sample 33_Baseline_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:M Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/F508del; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_175,VT_180710_M351_177,VT_180710_M351_179" SUBJECT_SAMPLE_FACTORS Serum Study Sample 35_Visit_2_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=visit_2; CF genotype=deltaF508/G542X; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_181,VT_180710_M351_183,VT_180710_M351_185" SUBJECT_SAMPLE_FACTORS Serum Study Sample 35_Baseline_1 INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=baseline; CF genotype=deltaF508/G542X; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_187,VT_180710_M351_189,VT_180710_M351_191" SUBJECT_SAMPLE_FACTORS Serum Study Sample 36_Baseline_1 INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:M Sample Matrix=Serum; Event Name=baseline; CF genotype=deltaF508 and G55.D Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_193,VT_180710_M351_195,VT_180710_M351_197" SUBJECT_SAMPLE_FACTORS Serum Study Sample 37_Baseline_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:M Sample Matrix=Serum; Event Name=baseline; CF genotype=deltaF508 and G55.D Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_199,VT_180710_M351_201,VT_180710_M351_203" SUBJECT_SAMPLE_FACTORS Serum Study Sample 38_Baseline_1 INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:M Sample Matrix=Serum; Event Name=baseline; CF genotype=DeltaF508/ c.2789+5G>A]; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_205,VT_180710_M351_207,VT_180710_M351_209" SUBJECT_SAMPLE_FACTORS Serum Study Sample 38_Visit_2_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:M Sample Matrix=Serum; Event Name=visit_2; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_211,VT_180710_M351_213,VT_180710_M351_215" SUBJECT_SAMPLE_FACTORS Serum Study Sample 42_Baseline_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:M Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_217,VT_180710_M351_219,VT_180710_M351_221" SUBJECT_SAMPLE_FACTORS Serum Study Sample 43_Visit_2_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=visit_2; CF genotype=F508del/F508del; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_223,VT_180710_M351_225,VT_180710_M351_227" SUBJECT_SAMPLE_FACTORS Serum Study Sample 43_Baseline_1 INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/F508del; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_229,VT_180710_M351_231,VT_180710_M351_233" SUBJECT_SAMPLE_FACTORS Serum Study Sample 44_Baseline_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:M Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/2789+5G->A; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_235,VT_180710_M351_237,VT_180710_M351_239" SUBJECT_SAMPLE_FACTORS Serum Study Sample 45_Baseline_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:M Sample Matrix=Serum; Event Name=baseline; CF genotype=621+1G>T/Delta F508; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_241,VT_180710_M351_243,VT_180710_M351_245" SUBJECT_SAMPLE_FACTORS Serum Study Sample 47_Baseline_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:M Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_247,VT_180710_M351_249,VT_180710_M351_251" SUBJECT_SAMPLE_FACTORS Serum Study Sample 49_Baseline_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=baseline; CF genotype=l507del/2622+1G>A; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_253,VT_180710_M351_255,VT_180710_M351_257" SUBJECT_SAMPLE_FACTORS Serum Study Sample 50_Baseline_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/F508del; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_259,VT_180710_M351_261,VT_180710_M351_263" SUBJECT_SAMPLE_FACTORS Serum Study Sample 51_Baseline_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_265,VT_180710_M351_267,VT_180710_M351_269" SUBJECT_SAMPLE_FACTORS Serum Study Sample 52_Baseline_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_271,VT_180710_M351_273,VT_180710_M351_275" SUBJECT_SAMPLE_FACTORS Serum Study Sample chearplasma_1e_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:- Sample Matrix=Serum; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_277,VT_180710_M351_279,VT_180710_M351_281" SUBJECT_SAMPLE_FACTORS Serum Study Sample chearplasma_1f_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:- Sample Matrix=Serum; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_283,VT_180710_M351_285,VT_180710_M351_287" SUBJECT_SAMPLE_FACTORS Quality Control Q-Std Plasma pool_1b_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:- Sample Matrix=Plasma; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Plasma; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_289,VT_180710_M351_291,VT_180710_M351_293" SUBJECT_SAMPLE_FACTORS Quality Control Q-Std Plasma pool_2a_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:- Sample Matrix=Plasma; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Plasma; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_001,VT_180711_M351_003,VT_180711_M351_005" SUBJECT_SAMPLE_FACTORS Serum Study Sample chearplasma_2a_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:- Sample Matrix=Serum; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_007,VT_180711_M351_009,VT_180711_M351_011" SUBJECT_SAMPLE_FACTORS Serum Study Sample chearplasma_2b_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:- Sample Matrix=Serum; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_013,VT_180711_M351_015,VT_180711_M351_017" SUBJECT_SAMPLE_FACTORS Serum Study Sample 54_Baseline_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:M Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/F508del; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_019,VT_180711_M351_021,VT_180711_M351_023" SUBJECT_SAMPLE_FACTORS Serum Study Sample 55_Baseline_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:M Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/F508del; Volume (uL)=160; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_025,VT_180711_M351_027,VT_180711_M351_029" SUBJECT_SAMPLE_FACTORS Serum Study Sample 58_Baseline_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/F508del; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_031,VT_180711_M351_033,VT_180711_M351_035" SUBJECT_SAMPLE_FACTORS Serum Study Sample 59_Baseline_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/F508del; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_037,VT_180711_M351_039,VT_180711_M351_041" SUBJECT_SAMPLE_FACTORS Serum Study Sample 60_Baseline_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:M Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/F508del; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_043,VT_180711_M351_045,VT_180711_M351_047" SUBJECT_SAMPLE_FACTORS Serum Study Sample 61_Baseline_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/F508del; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_049,VT_180711_M351_051,VT_180711_M351_053" SUBJECT_SAMPLE_FACTORS Serum Study Sample 63_Baseline_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:M Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/F508del; Volume (uL)=180; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_055,VT_180711_M351_057,VT_180711_M351_059" SUBJECT_SAMPLE_FACTORS Serum Study Sample 64_Baseline_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:M Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/ 2184delA); Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_061,VT_180711_M351_063,VT_180711_M351_065" SUBJECT_SAMPLE_FACTORS Serum Study Sample 65_Baseline_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=baseline; CF genotype="deltaF508, R 553X"; Volume (uL)=180; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_067,VT_180711_M351_069,VT_180711_M351_071" SUBJECT_SAMPLE_FACTORS Serum Study Sample 67_Baseline_1 INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:M Sample Matrix=Serum; Event Name=baseline; CF genotype=deltaF508/Y1092X; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_073,VT_180711_M351_075,VT_180711_M351_077" SUBJECT_SAMPLE_FACTORS Serum Study Sample 67_Visit_2_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:M Sample Matrix=Serum; Event Name=visit_2; CF genotype=deltaF508/Y1092X; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_079,VT_180711_M351_081,VT_180711_M351_083" SUBJECT_SAMPLE_FACTORS Serum Study Sample 68_Baseline_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=baseline; CF genotype="Delta F508, p.S489X "; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_085,VT_180711_M351_087,VT_180711_M351_089" SUBJECT_SAMPLE_FACTORS Serum Study Sample 69_Baseline_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_091,VT_180711_M351_093,VT_180711_M351_095" SUBJECT_SAMPLE_FACTORS Serum Study Sample 71_Baseline_1 INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=baseline; CF genotype=F4508del/ R117H (5T/9T; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_097,VT_180711_M351_099,VT_180711_M351_101" SUBJECT_SAMPLE_FACTORS Serum Study Sample 72_Baseline_1 INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=baseline; CF genotype=R553X/DeltaF508.; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_103,VT_180711_M351_105,VT_180711_M351_107" SUBJECT_SAMPLE_FACTORS Serum Study Sample 73_Baseline_1 INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=baseline; CF genotype=F508Del/F508Del; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_109,VT_180711_M351_111,VT_180711_M351_113" SUBJECT_SAMPLE_FACTORS Serum Study Sample 74_Baseline_1 INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_115,VT_180711_M351_117,VT_180711_M351_119" SUBJECT_SAMPLE_FACTORS Serum Study Sample 75_Baseline_1 INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:M Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=165; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_121,VT_180711_M351_123,VT_180711_M351_125" SUBJECT_SAMPLE_FACTORS Serum Study Sample 76_Baseline_1 INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:M Sample Matrix=Serum; Event Name=baseline; CF genotype=deltaF508 and 621+1G>T; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_127,VT_180711_M351_129,VT_180711_M351_131" SUBJECT_SAMPLE_FACTORS Serum Study Sample 78_Baseline_1 INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:M Sample Matrix=Serum; Event Name=baseline; CF genotype=R1162X/E193X; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_133,VT_180711_M351_135,VT_180711_M351_137" SUBJECT_SAMPLE_FACTORS Serum Study Sample chearplasma_2c_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:- Sample Matrix=Serum; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_139,VT_180711_M351_141,VT_180711_M351_143" SUBJECT_SAMPLE_FACTORS Serum Study Sample chearplasma_2d_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:- Sample Matrix=Serum; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_145,VT_180711_M351_147,VT_180711_M351_149" SUBJECT_SAMPLE_FACTORS Serum Study Sample 79_Baseline_1 INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/R785/S1235R; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_151,VT_180711_M351_153,VT_180711_M351_155" SUBJECT_SAMPLE_FACTORS Serum Study Sample 80_Baseline_1 INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/F508del; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_157,VT_180711_M351_159,VT_180711_M351_161" SUBJECT_SAMPLE_FACTORS Serum Study Sample ncH_001_1 INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:M Sample Matrix=Serum; Event Name=nch_001; CF genotype=F508del/3120+1G>A; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_163,VT_180711_M351_165,VT_180711_M351_167" SUBJECT_SAMPLE_FACTORS Serum Study Sample NCH_002_1 INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:M Sample Matrix=Serum; Event Name=nch_002; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_169,VT_180711_M351_171,VT_180711_M351_173" SUBJECT_SAMPLE_FACTORS Serum Study Sample NCH_003_1 INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:M Sample Matrix=Serum; Event Name=nch_003; CF genotype="F508del, Y1092X"; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_175,VT_180711_M351_177,VT_180711_M351_179" SUBJECT_SAMPLE_FACTORS Serum Study Sample hc_7_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:M Sample Matrix=Serum; Event Name=hc_7; CF genotype=-; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_181,VT_180711_M351_183,VT_180711_M351_185" SUBJECT_SAMPLE_FACTORS Serum Study Sample hc_12_1 INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:M Sample Matrix=Serum; Event Name=hc_12; CF genotype=-; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_187,VT_180711_M351_189,VT_180711_M351_191" SUBJECT_SAMPLE_FACTORS Serum Study Sample hc_15_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:M Sample Matrix=Serum; Event Name=hc_15; CF genotype=-; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_193,VT_180711_M351_195,VT_180711_M351_197" SUBJECT_SAMPLE_FACTORS Serum Study Sample hc_30_1 INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:M Sample Matrix=Serum; Event Name=hc_30; CF genotype=-; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_199,VT_180711_M351_201,VT_180711_M351_203" SUBJECT_SAMPLE_FACTORS Serum Study Sample hc_31_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:M Sample Matrix=Serum; Event Name=hc_31; CF genotype=-; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_205,VT_180711_M351_207,VT_180711_M351_209" SUBJECT_SAMPLE_FACTORS Serum Study Sample hc_32_1 INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:M Sample Matrix=Serum; Event Name=hc_32; CF genotype=-; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_211,VT_180711_M351_213,VT_180711_M351_215" SUBJECT_SAMPLE_FACTORS Serum Study Sample hc_48_1 INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:F Sample Matrix=Serum; Event Name=hc_48; CF genotype=-; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_217,VT_180711_M351_219,VT_180711_M351_221" SUBJECT_SAMPLE_FACTORS Serum Study Sample hc_60_1 INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:F Sample Matrix=Serum; Event Name=hc_60; CF genotype=-; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_223,VT_180711_M351_225,VT_180711_M351_227" SUBJECT_SAMPLE_FACTORS Serum Study Sample hc_62_1 INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:M Sample Matrix=Serum; Event Name=hc_62; CF genotype=-; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_229,VT_180711_M351_231,VT_180711_M351_233" SUBJECT_SAMPLE_FACTORS Serum Study Sample hc_64_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:M Sample Matrix=Serum; Event Name=hc_64; CF genotype=-; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_235,VT_180711_M351_237,VT_180711_M351_239" SUBJECT_SAMPLE_FACTORS Serum Study Sample ncf_106_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:M Sample Matrix=Serum; Event Name=ncf_106; CF genotype=-; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_241,VT_180711_M351_243,VT_180711_M351_245" SUBJECT_SAMPLE_FACTORS Serum Study Sample NCF_108_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:F Sample Matrix=Serum; Event Name=ncf_108; CF genotype=-; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_247,VT_180711_M351_249,VT_180711_M351_251" SUBJECT_SAMPLE_FACTORS Serum Study Sample ncf_110_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:F Sample Matrix=Serum; Event Name=ncf_110; CF genotype=-; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_253,VT_180711_M351_255,VT_180711_M351_257" SUBJECT_SAMPLE_FACTORS Serum Study Sample ncf_112_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:F Sample Matrix=Serum; Event Name=ncf_112; CF genotype=-; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_259,VT_180711_M351_261,VT_180711_M351_263" SUBJECT_SAMPLE_FACTORS Serum Study Sample ncf_114_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:F Sample Matrix=Serum; Event Name=ncf_114; CF genotype=-; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_265,VT_180711_M351_267,VT_180711_M351_269" SUBJECT_SAMPLE_FACTORS Serum Study Sample chearplasma_2e_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:- Sample Matrix=Serum; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_271,VT_180711_M351_273,VT_180711_M351_275" SUBJECT_SAMPLE_FACTORS Serum Study Sample chearplasma_2f_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:- Sample Matrix=Serum; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_277,VT_180711_M351_279,VT_180711_M351_281" SUBJECT_SAMPLE_FACTORS Quality Control Q-Std Plasma pool_2b_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:- Sample Matrix=Plasma; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Plasma; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_283,VT_180711_M351_285,VT_180711_M351_287" SUBJECT_SAMPLE_FACTORS Quality Control NIST SRM 1950_2_1 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:- Sample Matrix=Plasma; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Plasma; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_289,VT_180711_M351_291,VT_180711_M351_293" SUBJECT_SAMPLE_FACTORS Quality Control NIST SRM 1950_1_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:- Sample Matrix=Plasma; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Plasma; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_002,VT_180710_M351_004,VT_180710_M351_006" SUBJECT_SAMPLE_FACTORS Quality Control Q-Std Plasma pool_1a_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:- Sample Matrix=Plasma; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Plasma; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_008,VT_180710_M351_010,VT_180710_M351_012" SUBJECT_SAMPLE_FACTORS Serum Study Sample chearplasma_1a_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:- Sample Matrix=Serum; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_014,VT_180710_M351_016,VT_180710_M351_018" SUBJECT_SAMPLE_FACTORS Serum Study Sample chearplasma_1b_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:- Sample Matrix=Serum; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_020,VT_180710_M351_022,VT_180710_M351_024" SUBJECT_SAMPLE_FACTORS Serum Study Sample 3_Baseline_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_026,VT_180710_M351_028,VT_180710_M351_030" SUBJECT_SAMPLE_FACTORS Serum Study Sample 4_Baseline_2 INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:M Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_032,VT_180710_M351_034,VT_180710_M351_036" SUBJECT_SAMPLE_FACTORS Serum Study Sample 5_Baseline_2 INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_038,VT_180710_M351_040,VT_180710_M351_042" SUBJECT_SAMPLE_FACTORS Serum Study Sample 6_Baseline_2 INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:M Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_044,VT_180710_M351_046,VT_180710_M351_048" SUBJECT_SAMPLE_FACTORS Serum Study Sample 7_Baseline_2 INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_050,VT_180710_M351_052,VT_180710_M351_054" SUBJECT_SAMPLE_FACTORS Serum Study Sample 8_Baseline_2 INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_056,VT_180710_M351_058,VT_180710_M351_060" SUBJECT_SAMPLE_FACTORS Serum Study Sample 8_Visit_2_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=visit_2; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_062,VT_180710_M351_064,VT_180710_M351_066" SUBJECT_SAMPLE_FACTORS Serum Study Sample 9_Baseline_2 INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:M Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_068,VT_180710_M351_070,VT_180710_M351_072" SUBJECT_SAMPLE_FACTORS Serum Study Sample 10_Visit_2_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:M Sample Matrix=Serum; Event Name=visit_2; CF genotype=F508 del /1898+1G>A; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_074,VT_180710_M351_076,VT_180710_M351_078" SUBJECT_SAMPLE_FACTORS Serum Study Sample 10_Baseline_2 INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:M Sample Matrix=Serum; Event Name=baseline; CF genotype=F508 del /1898+1G>A; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_080,VT_180710_M351_082,VT_180710_M351_084" SUBJECT_SAMPLE_FACTORS Serum Study Sample 11_Baseline_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=baseline; CF genotype=R74Q/R297Q; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_086,VT_180710_M351_088,VT_180710_M351_090" SUBJECT_SAMPLE_FACTORS Serum Study Sample 12_Baseline_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=baseline; CF genotype=R74Q/R297Q; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_092,VT_180710_M351_094,VT_180710_M351_096" SUBJECT_SAMPLE_FACTORS Serum Study Sample 14_Baseline_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_098,VT_180710_M351_100,VT_180710_M351_102" SUBJECT_SAMPLE_FACTORS Serum Study Sample 15_Baseline_2 INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_104,VT_180710_M351_106,VT_180710_M351_108" SUBJECT_SAMPLE_FACTORS Serum Study Sample 23_Visit_2_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=visit_2; CF genotype=F508del/Unknown; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_110,VT_180710_M351_112,VT_180710_M351_114" SUBJECT_SAMPLE_FACTORS Serum Study Sample 25_Baseline_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:M Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_116,VT_180710_M351_118,VT_180710_M351_120" SUBJECT_SAMPLE_FACTORS Serum Study Sample 26_Baseline_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, CFTR del 2,3"; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_122,VT_180710_M351_124,VT_180710_M351_126" SUBJECT_SAMPLE_FACTORS Serum Study Sample 27_Baseline_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:M Sample Matrix=Serum; Event Name=baseline; CF genotype=Delta F 508/Q493X; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_128,VT_180710_M351_130,VT_180710_M351_132" SUBJECT_SAMPLE_FACTORS Serum Study Sample 28_Baseline_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=baseline; CF genotype=" F508del, 3849 + 10kb C>T"; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_134,VT_180710_M351_136,VT_180710_M351_138" SUBJECT_SAMPLE_FACTORS Serum Study Sample 29_Baseline_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/F508del; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_140,VT_180710_M351_142,VT_180710_M351_144" SUBJECT_SAMPLE_FACTORS Serum Study Sample chearplasma_1c_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:- Sample Matrix=Serum; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_146,VT_180710_M351_148,VT_180710_M351_150" SUBJECT_SAMPLE_FACTORS Serum Study Sample chearplasma_1d_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:- Sample Matrix=Serum; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_152,VT_180710_M351_154,VT_180710_M351_156" SUBJECT_SAMPLE_FACTORS Serum Study Sample 30_Baseline_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:M Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/F508del; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_158,VT_180710_M351_160,VT_180710_M351_162" SUBJECT_SAMPLE_FACTORS Serum Study Sample 31_Baseline_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:M Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/F508del; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_164,VT_180710_M351_166,VT_180710_M351_168" SUBJECT_SAMPLE_FACTORS Serum Study Sample 32_Baseline_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=baseline; CF genotype=R560T/R1158X; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_170,VT_180710_M351_172,VT_180710_M351_174" SUBJECT_SAMPLE_FACTORS Serum Study Sample 33_Baseline_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:M Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/F508del; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_176,VT_180710_M351_178,VT_180710_M351_180" SUBJECT_SAMPLE_FACTORS Serum Study Sample 35_Visit_2_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=visit_2; CF genotype=deltaF508/G542X; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_182,VT_180710_M351_184,VT_180710_M351_186" SUBJECT_SAMPLE_FACTORS Serum Study Sample 35_Baseline_2 INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=baseline; CF genotype=deltaF508/G542X; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_188,VT_180710_M351_190,VT_180710_M351_192" SUBJECT_SAMPLE_FACTORS Serum Study Sample 36_Baseline_2 INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:M Sample Matrix=Serum; Event Name=baseline; CF genotype=deltaF508 and G55.D Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_194,VT_180710_M351_196,VT_180710_M351_198" SUBJECT_SAMPLE_FACTORS Serum Study Sample 37_Baseline_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:M Sample Matrix=Serum; Event Name=baseline; CF genotype=deltaF508 and G55.D Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_200,VT_180710_M351_202,VT_180710_M351_204" SUBJECT_SAMPLE_FACTORS Serum Study Sample 38_Baseline_2 INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:M Sample Matrix=Serum; Event Name=baseline; CF genotype=DeltaF508/ c.2789+5G>A]; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_206,VT_180710_M351_208,VT_180710_M351_210" SUBJECT_SAMPLE_FACTORS Serum Study Sample 38_Visit_2_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:M Sample Matrix=Serum; Event Name=visit_2; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_212,VT_180710_M351_214,VT_180710_M351_216" SUBJECT_SAMPLE_FACTORS Serum Study Sample 42_Baseline_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:M Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_218,VT_180710_M351_220,VT_180710_M351_222" SUBJECT_SAMPLE_FACTORS Serum Study Sample 43_Visit_2_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=visit_2; CF genotype=F508del/F508del; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_224,VT_180710_M351_226,VT_180710_M351_228" SUBJECT_SAMPLE_FACTORS Serum Study Sample 43_Baseline_2 INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/F508del; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_230,VT_180710_M351_232,VT_180710_M351_234" SUBJECT_SAMPLE_FACTORS Serum Study Sample 44_Baseline_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:M Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/2789+5G->A; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_236,VT_180710_M351_238,VT_180710_M351_240" SUBJECT_SAMPLE_FACTORS Serum Study Sample 45_Baseline_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:M Sample Matrix=Serum; Event Name=baseline; CF genotype=621+1G>T/Delta F508; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_242,VT_180710_M351_244,VT_180710_M351_246" SUBJECT_SAMPLE_FACTORS Serum Study Sample 47_Baseline_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:M Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_248,VT_180710_M351_250,VT_180710_M351_252" SUBJECT_SAMPLE_FACTORS Serum Study Sample 49_Baseline_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=baseline; CF genotype=l507del/2622+1G>A; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_254,VT_180710_M351_256,VT_180710_M351_258" SUBJECT_SAMPLE_FACTORS Serum Study Sample 50_Baseline_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/F508del; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_260,VT_180710_M351_262,VT_180710_M351_264" SUBJECT_SAMPLE_FACTORS Serum Study Sample 51_Baseline_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_266,VT_180710_M351_268,VT_180710_M351_270" SUBJECT_SAMPLE_FACTORS Serum Study Sample 52_Baseline_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_272,VT_180710_M351_274,VT_180710_M351_276" SUBJECT_SAMPLE_FACTORS Serum Study Sample chearplasma_1e_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:- Sample Matrix=Serum; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_278,VT_180710_M351_280,VT_180710_M351_282" SUBJECT_SAMPLE_FACTORS Serum Study Sample chearplasma_1f_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:- Sample Matrix=Serum; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_284,VT_180710_M351_286,VT_180710_M351_288" SUBJECT_SAMPLE_FACTORS Quality Control Q-Std Plasma pool_1b_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:- Sample Matrix=Plasma; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Plasma; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_290,VT_180710_M351_292,VT_180710_M351_294" SUBJECT_SAMPLE_FACTORS Quality Control Q-Std Plasma pool_2a_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:- Sample Matrix=Plasma; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Plasma; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_002,VT_180711_M351_004,VT_180711_M351_006" SUBJECT_SAMPLE_FACTORS Serum Study Sample chearplasma_2a_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:- Sample Matrix=Serum; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_008,VT_180711_M351_010,VT_180711_M351_012" SUBJECT_SAMPLE_FACTORS Serum Study Sample chearplasma_2b_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:- Sample Matrix=Serum; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_014,VT_180711_M351_016,VT_180711_M351_018" SUBJECT_SAMPLE_FACTORS Serum Study Sample 54_Baseline_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:M Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/F508del; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_020,VT_180711_M351_022,VT_180711_M351_024" SUBJECT_SAMPLE_FACTORS Serum Study Sample 55_Baseline_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:M Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/F508del; Volume (uL)=160; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_026,VT_180711_M351_028,VT_180711_M351_030" SUBJECT_SAMPLE_FACTORS Serum Study Sample 58_Baseline_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/F508del; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_032,VT_180711_M351_034,VT_180711_M351_036" SUBJECT_SAMPLE_FACTORS Serum Study Sample 59_Baseline_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/F508del; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_038,VT_180711_M351_040,VT_180711_M351_042" SUBJECT_SAMPLE_FACTORS Serum Study Sample 60_Baseline_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:M Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/F508del; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_044,VT_180711_M351_046,VT_180711_M351_048" SUBJECT_SAMPLE_FACTORS Serum Study Sample 61_Baseline_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/F508del; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_050,VT_180711_M351_052,VT_180711_M351_054" SUBJECT_SAMPLE_FACTORS Serum Study Sample 63_Baseline_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:M Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/F508del; Volume (uL)=180; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_056,VT_180711_M351_058,VT_180711_M351_060" SUBJECT_SAMPLE_FACTORS Serum Study Sample 64_Baseline_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:M Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/ 2184delA); Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_062,VT_180711_M351_064,VT_180711_M351_066" SUBJECT_SAMPLE_FACTORS Serum Study Sample 65_Baseline_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=baseline; CF genotype="deltaF508, R 553X"; Volume (uL)=180; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_068,VT_180711_M351_070,VT_180711_M351_072" SUBJECT_SAMPLE_FACTORS Serum Study Sample 67_Baseline_2 INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:M Sample Matrix=Serum; Event Name=baseline; CF genotype=deltaF508/Y1092X; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_074,VT_180711_M351_076,VT_180711_M351_078" SUBJECT_SAMPLE_FACTORS Serum Study Sample 67_Visit_2_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:M Sample Matrix=Serum; Event Name=visit_2; CF genotype=deltaF508/Y1092X; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_080,VT_180711_M351_082,VT_180711_M351_084" SUBJECT_SAMPLE_FACTORS Serum Study Sample 68_Baseline_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=baseline; CF genotype="Delta F508, p.S489X "; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_086,VT_180711_M351_088,VT_180711_M351_090" SUBJECT_SAMPLE_FACTORS Serum Study Sample 69_Baseline_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_092,VT_180711_M351_094,VT_180711_M351_096" SUBJECT_SAMPLE_FACTORS Serum Study Sample 71_Baseline_2 INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=baseline; CF genotype=F4508del/ R117H (5T/9T; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_098,VT_180711_M351_100,VT_180711_M351_102" SUBJECT_SAMPLE_FACTORS Serum Study Sample 72_Baseline_2 INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=baseline; CF genotype=R553X/DeltaF508.; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_104,VT_180711_M351_106,VT_180711_M351_108" SUBJECT_SAMPLE_FACTORS Serum Study Sample 73_Baseline_2 INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=baseline; CF genotype=F508Del/F508Del; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_110,VT_180711_M351_112,VT_180711_M351_114" SUBJECT_SAMPLE_FACTORS Serum Study Sample 74_Baseline_2 INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_116,VT_180711_M351_118,VT_180711_M351_120" SUBJECT_SAMPLE_FACTORS Serum Study Sample 75_Baseline_2 INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:M Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=165; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_122,VT_180711_M351_124,VT_180711_M351_126" SUBJECT_SAMPLE_FACTORS Serum Study Sample 76_Baseline_2 INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:M Sample Matrix=Serum; Event Name=baseline; CF genotype=deltaF508 and 621+1G>T; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_128,VT_180711_M351_130,VT_180711_M351_132" SUBJECT_SAMPLE_FACTORS Serum Study Sample 78_Baseline_2 INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:M Sample Matrix=Serum; Event Name=baseline; CF genotype=R1162X/E193X; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_134,VT_180711_M351_136,VT_180711_M351_138" SUBJECT_SAMPLE_FACTORS Serum Study Sample chearplasma_2c_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:- Sample Matrix=Serum; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_140,VT_180711_M351_142,VT_180711_M351_144" SUBJECT_SAMPLE_FACTORS Serum Study Sample chearplasma_2d_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:- Sample Matrix=Serum; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_146,VT_180711_M351_148,VT_180711_M351_150" SUBJECT_SAMPLE_FACTORS Serum Study Sample 79_Baseline_2 INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/R785/S1235R; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_152,VT_180711_M351_154,VT_180711_M351_156" SUBJECT_SAMPLE_FACTORS Serum Study Sample 80_Baseline_2 INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:F Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/F508del; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_158,VT_180711_M351_160,VT_180711_M351_162" SUBJECT_SAMPLE_FACTORS Serum Study Sample ncH_001_2 INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:M Sample Matrix=Serum; Event Name=nch_001; CF genotype=F508del/3120+1G>A; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_164,VT_180711_M351_166,VT_180711_M351_168" SUBJECT_SAMPLE_FACTORS Serum Study Sample NCH_002_2 INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:M Sample Matrix=Serum; Event Name=nch_002; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_170,VT_180711_M351_172,VT_180711_M351_174" SUBJECT_SAMPLE_FACTORS Serum Study Sample NCH_003_2 INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:M Sample Matrix=Serum; Event Name=nch_003; CF genotype="F508del, Y1092X"; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_176,VT_180711_M351_178,VT_180711_M351_180" SUBJECT_SAMPLE_FACTORS Serum Study Sample hc_7_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:M Sample Matrix=Serum; Event Name=hc_7; CF genotype=-; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_182,VT_180711_M351_184,VT_180711_M351_186" SUBJECT_SAMPLE_FACTORS Serum Study Sample hc_12_2 INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:M Sample Matrix=Serum; Event Name=hc_12; CF genotype=-; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_188,VT_180711_M351_190,VT_180711_M351_192" SUBJECT_SAMPLE_FACTORS Serum Study Sample hc_15_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:M Sample Matrix=Serum; Event Name=hc_15; CF genotype=-; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_194,VT_180711_M351_196,VT_180711_M351_198" SUBJECT_SAMPLE_FACTORS Serum Study Sample hc_30_2 INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:M Sample Matrix=Serum; Event Name=hc_30; CF genotype=-; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_200,VT_180711_M351_202,VT_180711_M351_204" SUBJECT_SAMPLE_FACTORS Serum Study Sample hc_31_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:M Sample Matrix=Serum; Event Name=hc_31; CF genotype=-; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_206,VT_180711_M351_208,VT_180711_M351_210" SUBJECT_SAMPLE_FACTORS Serum Study Sample hc_32_2 INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:M Sample Matrix=Serum; Event Name=hc_32; CF genotype=-; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_212,VT_180711_M351_214,VT_180711_M351_216" SUBJECT_SAMPLE_FACTORS Serum Study Sample hc_48_2 INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:F Sample Matrix=Serum; Event Name=hc_48; CF genotype=-; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_218,VT_180711_M351_220,VT_180711_M351_222" SUBJECT_SAMPLE_FACTORS Serum Study Sample hc_60_2 INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:F Sample Matrix=Serum; Event Name=hc_60; CF genotype=-; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_224,VT_180711_M351_226,VT_180711_M351_228" SUBJECT_SAMPLE_FACTORS Serum Study Sample hc_62_2 INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:M Sample Matrix=Serum; Event Name=hc_62; CF genotype=-; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_230,VT_180711_M351_232,VT_180711_M351_234" SUBJECT_SAMPLE_FACTORS Serum Study Sample hc_64_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:M Sample Matrix=Serum; Event Name=hc_64; CF genotype=-; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_236,VT_180711_M351_238,VT_180711_M351_240" SUBJECT_SAMPLE_FACTORS Serum Study Sample ncf_106_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:M Sample Matrix=Serum; Event Name=ncf_106; CF genotype=-; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_242,VT_180711_M351_244,VT_180711_M351_246" SUBJECT_SAMPLE_FACTORS Serum Study Sample NCF_108_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:F Sample Matrix=Serum; Event Name=ncf_108; CF genotype=-; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_248,VT_180711_M351_250,VT_180711_M351_252" SUBJECT_SAMPLE_FACTORS Serum Study Sample ncf_110_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:F Sample Matrix=Serum; Event Name=ncf_110; CF genotype=-; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_254,VT_180711_M351_256,VT_180711_M351_258" SUBJECT_SAMPLE_FACTORS Serum Study Sample ncf_112_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:F Sample Matrix=Serum; Event Name=ncf_112; CF genotype=-; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_260,VT_180711_M351_262,VT_180711_M351_264" SUBJECT_SAMPLE_FACTORS Serum Study Sample ncf_114_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:F Sample Matrix=Serum; Event Name=ncf_114; CF genotype=-; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_266,VT_180711_M351_268,VT_180711_M351_270" SUBJECT_SAMPLE_FACTORS Serum Study Sample chearplasma_2e_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:- Sample Matrix=Serum; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_272,VT_180711_M351_274,VT_180711_M351_276" SUBJECT_SAMPLE_FACTORS Serum Study Sample chearplasma_2f_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:- Sample Matrix=Serum; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_278,VT_180711_M351_280,VT_180711_M351_282" SUBJECT_SAMPLE_FACTORS Quality Control Q-Std Plasma pool_2b_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:- Sample Matrix=Plasma; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Plasma; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_284,VT_180711_M351_286,VT_180711_M351_288" SUBJECT_SAMPLE_FACTORS Quality Control NIST SRM 1950_2_2 INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:- Sample Matrix=Plasma; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Plasma; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_290,VT_180711_M351_292,VT_180711_M351_294" #COLLECTION CO:COLLECTION_SUMMARY Blood plasma samples were collected from nonfasting participants in the CO:COLLECTION_SUMMARY Aspirin/Folate Polyp Prevention Study [1, 2] at enrollment (baseline) and after CO:COLLECTION_SUMMARY three years of study treatment. Blood samples were collected in tubes containing CO:COLLECTION_SUMMARY EDTA and after centrifugation aliquots of plasma were transferred to 1.8 ml CO:COLLECTION_SUMMARY freezer tubes and stored in a -70C freezer. The samples were shipped on dry ice CO:COLLECTION_SUMMARY from the clinical centers to the Dartmouth biorepository storage facility and CO:COLLECTION_SUMMARY subsequently to the metabolomics analysis lab at Emory University. CO:SAMPLE_TYPE Serum CO:STORAGE_CONDITIONS Described in summary #TREATMENT TR:TREATMENT_SUMMARY Samples were received frozen in aliquouts of <250uL. Prior to analysis, samples TR:TREATMENT_SUMMARY were thawed and prepared for HRM analysis using the standard protocols described TR:TREATMENT_SUMMARY in the Sample Preparation section. #SAMPLEPREP SP:SAMPLEPREP_SUMMARY Samples were prepared for metabolomics analysis using established SP:SAMPLEPREP_SUMMARY methods(Johnson et al. (2010). Analyst; Go et al. (2015). Tox Sci). Prior to SP:SAMPLEPREP_SUMMARY analysis, plasma aliquots were removed from storage at -80 degrees C and thawed SP:SAMPLEPREP_SUMMARY on ice. Each cryotube was then vortexed briefly to ensure homogeneity, and 50 SP:SAMPLEPREP_SUMMARY microliters was transferred to a clean microfuge tube. Immediately after, the SP:SAMPLEPREP_SUMMARY plasma was treated with 100 microliters of ice-cold LC-MS grade acetonitrile SP:SAMPLEPREP_SUMMARY (Sigma Aldrich) containing 2.5 microliters of internal standard solution with SP:SAMPLEPREP_SUMMARY eight stable isotopic chemicals selected to cover a range of chemical SP:SAMPLEPREP_SUMMARY properties. Following addition of acetonitrile, urine was equilibrated for 30 SP:SAMPLEPREP_SUMMARY min on ice, upon which precipitated proteins were removed by centrifuge (14,000 SP:SAMPLEPREP_SUMMARY rpm at 4 degrees C for 10 min). The resulting supernatant (100 microliters) was SP:SAMPLEPREP_SUMMARY removed, added to a low volume autosampler vial and maintained at 4 degrees C SP:SAMPLEPREP_SUMMARY until analysis (<22 h). SP:SAMPLEPREP_PROTOCOL_ID HRM_SP_082016_01 SP:SAMPLEPREP_PROTOCOL_FILENAME EmoryUniversity_HRM_sample_preparation_082016_01.pdf SP:SAMPLEPREP_PROTOCOL_COMMENTS Date effective: 30 July 2016 SP:EXTRACTION_METHOD 2:1 acetonitrile: sample followed by vortexing and centrifugation #CHROMATOGRAPHY CH:CHROMATOGRAPHY_SUMMARY The HILIC column is operated parallel to reverse phase column for CH:CHROMATOGRAPHY_SUMMARY simultaneous analytical separation and column flushing through the use of a CH:CHROMATOGRAPHY_SUMMARY dual head HPLC pump equipped with 10-port and 6-port switching valves. During CH:CHROMATOGRAPHY_SUMMARY operation of "HILIC separation method, the MS is operated in positive ion CH:CHROMATOGRAPHY_SUMMARY mode and 10" microliters of sample is injected onto the HILIC column while CH:CHROMATOGRAPHY_SUMMARY the reverse phase column is flushing with wash solution. Flow rate is CH:CHROMATOGRAPHY_SUMMARY maintained at 0.35 mL/min "until 1.5 min, increased to 0.4 mL/min at 4 min CH:CHROMATOGRAPHY_SUMMARY and held for 1 min. Solvent A is" "100% LC-MS grade water, solvent B is 100% CH:CHROMATOGRAPHY_SUMMARY LC-MS grade acetonitrile and solvent C" is 2% formic acid (v/v) in LC-MS CH:CHROMATOGRAPHY_SUMMARY grade water. Initial mobile phase conditions "are 22.5% A, 75% B, 2.5% C hold CH:CHROMATOGRAPHY_SUMMARY for 1.5 min, with linear gradient to 77.5% A," "20% B, 2.5% C at 4 min, hold CH:CHROMATOGRAPHY_SUMMARY for 1 min, resulting in a total analytical run time" "of 5 min. During the CH:CHROMATOGRAPHY_SUMMARY flushing phase (reverse phase analytical separation), the" "HILIC column is CH:CHROMATOGRAPHY_SUMMARY equilibrated with a wash solution of 77.5% A, 20% B, 2.5% C." CH:CHROMATOGRAPHY_TYPE HILIC CH:COLUMN_NAME Waters XBridge Amide (50 x 2.1mm, 2.5um) CH:COLUMN_NAME with Thermo Accucore HILIC guard column CH:FLOW_RATE 0.35 mL/min for 1.5 min; linear increase to 0.4 mL/min at 4 min, hold for 1 min CH:COLUMN_TEMPERATURE 60C CH:METHODS_FILENAME 20160920_posHILIC120kres5min_ESI_c18negwash.meth CH:SOLVENT_A LC-MS grade water CH:SOLVENT_B LC-MS grade acetonitrile CH:METHODS_ID 2% formic acid in LC-MS grade water CH:SAMPLE_INJECTION 10 uL CH:ANALYTICAL_TIME 5 min CH:SAMPLE_LOOP_SIZE 15 uL CH:SAMPLE_SYRINGE_SIZE 100 uL CH:CHROMATOGRAPHY_COMMENTS Triplicate injections for each chromatography mode CH:INSTRUMENT_NAME Thermo Dionex Ultimate 3000 #ANALYSIS AN:ANALYSIS_TYPE MS AN:LABORATORY_NAME Clinical Biomarkers Laboratory AN:OPERATOR_NAME Vilinh Tran AN:DETECTOR_TYPE Orbitrap AN:SOFTWARE_VERSION Xcalibur 3.0.63 AN:ACQUISITION_DATE Jan-15 AN:ANALYSIS_PROTOCOL_FILE EmoryUniversity_HRM_QEHF-MassSpec_092017_v1.pdf AN:DATA_FORMAT Profile #MS MS:INSTRUMENT_NAME Thermo Q Exactive HF hybrid Orbitrap MS:INSTRUMENT_NAME Thermo Q Exactive HF hybrid Orbitrap MS:INSTRUMENT_TYPE Orbitrap MS:MS_TYPE ESI MS:ION_MODE POSITIVE MS:MS_COMMENTS None MS:ACQUISITION_DATE Jan-15 MS:CAPILLARY_TEMPERATURE 250C MS:COLLISION_GAS N2 MS:DRY_GAS_FLOW 45 MS:DRY_GAS_TEMP 150C MS:MASS_ACCURACY < 3ppm MS:SPRAY_VOLTAGE 3500 MS:ACTIVATION_PARAMETER 5.00E+05 MS:ACTIVATION_TIME 118ms MS:INTERFACE_VOLTAGE S-Lens RF level= 55 MS:SCANNING_RANGE 85-1275 MS:MS_RESULTS_FILE ST001079_AN001761_Results.txt UNITS:Peak area #MS_METABOLITE_DATA MS_METABOLITE_DATA:UNITS Peak Area MS_METABOLITE_DATA_START Samples NIST SRM 1950_1_1 Q-Std Plasma pool_1a_1 chearplasma_1a_1 chearplasma_1b_1 3_Baseline_1 4_Baseline_1 5_Baseline_1 6_Baseline_1 7_Baseline_1 8_Baseline_1 8_Visit_2_1 9_Baseline_1 10_Visit_2_1 10_Baseline_1 11_Baseline_1 12_Baseline_1 14_Baseline_1 15_Baseline_1 23_Visit_2_1 25_Baseline_1 26_Baseline_1 27_Baseline_1 28_Baseline_1 29_Baseline_1 chearplasma_1c_1 chearplasma_1d_1 30_Baseline_1 31_Baseline_1 32_Baseline_1 33_Baseline_1 35_Visit_2_1 35_Baseline_1 36_Baseline_1 37_Baseline_1 38_Baseline_1 38_Visit_2_1 42_Baseline_1 43_Visit_2_1 43_Baseline_1 44_Baseline_1 45_Baseline_1 47_Baseline_1 49_Baseline_1 50_Baseline_1 51_Baseline_1 52_Baseline_1 chearplasma_1e_1 chearplasma_1f_1 Q-Std Plasma pool_1b_1 Q-Std Plasma pool_2a_1 chearplasma_2a_1 chearplasma_2b_1 54_Baseline_1 55_Baseline_1 58_Baseline_1 59_Baseline_1 60_Baseline_1 61_Baseline_1 63_Baseline_1 64_Baseline_1 65_Baseline_1 67_Baseline_1 67_Visit_2_1 68_Baseline_1 69_Baseline_1 71_Baseline_1 72_Baseline_1 73_Baseline_1 74_Baseline_1 75_Baseline_1 76_Baseline_1 78_Baseline_1 chearplasma_2c_1 chearplasma_2d_1 79_Baseline_1 80_Baseline_1 ncH_001_1 NCH_002_1 NCH_003_1 hc_7_1 hc_12_1 hc_15_1 hc_30_1 hc_31_1 hc_32_1 hc_48_1 hc_60_1 hc_62_1 hc_64_1 ncf_106_1 NCF_108_1 ncf_110_1 ncf_112_1 ncf_114_1 chearplasma_2e_1 chearplasma_2f_1 Q-Std Plasma pool_2b_1 NIST SRM 1950_2_1 Factors INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:- INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:- INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:- INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:- INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:F INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:M INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:F INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:M INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:F INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:F INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:F INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:M INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:M INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:M INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:F INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:F INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:F INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:F INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:F INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:M INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:F INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:M INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:F INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:F INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:- INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:- INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:M INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:M INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:F INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:M INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:F INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:F INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:M INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:M INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:M INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:M INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:M INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:F INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:F INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:M INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:M INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:M INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:F INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:F INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:F INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:F INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:- INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:- INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:- INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:- INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:- INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:- INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:M INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:M INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:F INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:F INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:M INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:F INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:M INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:M INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:F INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:M INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:M INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:F INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:F INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:F INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:F INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:F INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:F INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:M INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:M INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:M INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:- INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:- INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:F INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:1 | Gender:F INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:M INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:1 | CF? 1=Yes 0=No:1 | Gender:M INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:M INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:M INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:M INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:M INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:M INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:M INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:M INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:F INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:F INFANT? 1=YES 0=CHILD:1 | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:M INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:M INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:M INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:F INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:F INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:F INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:F INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:- INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:- INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:- INFANT? 1=YES 0=CHILD:- | Smoke exposure? 1=Yes 0=No:- | CF? 1=Yes 0=No:- | Gender:- Benzylamine 2545897.2 2302062.2 1187717.1 1448123.9 1025489.1 12232188.2 936505.9 910249.3 1028232.7 1711860.1 898250.3 1300780.3 850810.1 736000.4 849071.5 847698.3 927363.1 1460527.2 914800.2 876655.4 787920.7 811827.9 889909 823558.5 1377495 1296757.3 901073.7 817816 899735.3 819191.2 843277.1 1195300.9 808405.8 803635.3 1563345.8 856775.1 890892 847299.1 910159.5 921061.7 796967.6 798461.6 742981.4 805780 881628.5 841630.4 1404666.7 1305523.8 1049449.3 959048.6 2075966.1 1272985.3 821060 648703.2 802063.6 531160.8 746153.8 568709.5 708299.9 659811.2 778412.8 1008982 579656.5 720058.4 667451.9 582353.7 689816 698066.8 785597.3 721493.1 792285.5 723801.7 1324878 1532440.8 680770.9 734323.8 1631144.8 3468372.4 2084733.3 713358.1 763472.8 705913.8 626088.3 813610.7 579043.4 750107.5 778656.4 689799.9 618278.5 11548985 3449123.3 2038745.5 1366444.9 1486722.8 1559981.9 1570613.7 1717935.4 1018163.1 Hypotaurine 8017492.8 15445308.1 1837176.2 7010656.1 5024297.2 2273555.1 5222060.7 9651248 354248 2765256.3 2963288.4 1767124.6 1611672.6 1899469.2 11425185.3 9920217.2 8512682.8 434930.9 368434.2 1945194.9 2295374.6 2511158.1 1360104.8 1718036.2 324523.3 2346525.8 392255.5 4406434.6 1378118.8 714477.2 1402449.8 4076483.5 666592.7 1189114.3 2808930.4 1308889.2 2221548.5 6179632.2 2504227.6 1118217.6 638454.5 351418.1 329695.6 2025910.4 170269.6 398443.8 715370.5 0 7566421.3 10496890.9 0 0 610955.1 474103.9 5267584.2 4332566.5 1176346.9 681209.4 4033566.2 745624.4 2030308.2 2087409.6 855029.6 804202.6 4683114 12609835.5 8288819.4 5568370 2419440.2 7638767.6 5386459.8 1153497.3 1293943.4 1080109.5 880533.8 714077.1 3063108.7 1567524.5 1407274.8 2772502.3 1452665.1 1284916.8 674127.2 2492399.1 183069.2 253365.4 6688679 1003655.8 1046339 761654.4 127240 359999.7 353316.4 230462 411672 343957.3 1592029 9009856.9 Histamine 37994680.2 23592436.7 28061471.1 28188830.8 37970632.5 1884564.8 39239853 38913060.7 14016140.9 16921212.3 21547650.2 39579680.8 37621678.4 72592423.5 33682892.1 34649432.1 71021266.1 7652590.3 42224145.7 39499006 27630787.1 51702619.1 52701636.3 51560746.5 30844923.6 31071522.2 63283976.6 48143364.4 51968526 55615354.6 61381376 32258736.6 50576855.8 68597543.7 17730428.8 25296186.2 38922269.1 47343177.2 28152082.1 32305858.9 62066234.9 54864728.2 37161811.4 55423659.9 49504294 36448875.8 33140701.7 32070704.6 29722287.5 31374527 29876119.6 31760830.6 43353585.4 56756288.1 57579897.5 68456174.7 48809032.6 34019261.6 44879102.8 41454895.3 55612998.3 16504087.6 36197733.9 25244687.7 47289741.4 51567306.6 63059073.5 57192885.1 56355714.7 70973290.5 59891597.1 36677785.7 35081685.5 34427400.4 52313286 53754394.9 21963385.2 21350752.5 30118358.4 25779948 40977519 26791284.5 33034780.5 26352294.6 35120754.6 56660159 49928930.4 32435601.6 26481906.2 12594637.6 10641058.9 9738940.4 14023912.7 8342813 37787403.5 36595290.9 36988006.1 27002067.7 Creatinine 4382999478 4399561671 4374030699 4386768025 2810952743 245978054.6 1925793979 1533301552 253536485 247720620.4 1598970762 246212843.3 2256761282 1802732948 3093919199 3609067455 2923221572 247758222 1867237466 3881977333 2441829162 1758892242 2463816928 2851262465 4704164716 4511452601 2665460333 2607842118 2413203165 3558883312 1724068589 251182320.4 1830984215 2229205043 250265630 1677959216 2253441340 1862925939 2001605474 2799481943 2843765085 2699180782 2615890059 3412188893 2751087431 1860970738 4639609482 4702743958 4344467339 4054862348 4621185923 4515302202 3106279079 3357083890 5567927583 5402115232 2238005891 1665966622 1730983370 2868403417 2052443850 0 1945957426 1969610962 2133363831 2030317577 1948162211 1981329150 1814710681 1638948317 1487187793 1491419461 4453939192 4293502089 1885831556 1589218142 2022789464 1476700653 1438511933 2256832651 2052727898 2681808039 1627458111 1841268402 1692928003 1409418778 1759227464 1778364239 3354441825 3497211834 1655041331 2446732850 1760259732 1719512047 4552235473 4683213416 4515722398 4057550275 Proline 1032417102 3009690700 961515907 1005109649 947942944.6 1024606815 1417019597 958091289.7 1053611427 891165447 825773132.2 2234974897 603625632.3 1238053096 1604995722 1910781823 1468383393 947628265.1 1313239490 1057134165 1460619834 1202595140 1947867235 1238701891 1132007284 1116105332 2076970371 1598850923 1170345476 1653166116 1064749901 880076944.3 1546819186 1149253534 604765483.2 773124550.8 987653127.8 1972541024 974103256.6 876336960.4 1028188365 932891163.1 1421995875 1349850952 1255474204 889242430.2 1143283492 1248144069 1657925233 1856119373 1280750828 1141642725 1546971271 1738639776 1995536253 1748844174 2464247099 2413140021 1242733064 796661587.4 1698907469 796193695.7 1426469645 1087096666 1150322629 1018418850 1721623436 1687387830 1157201782 1393444595 1139546807 1327649877 1215451579 1194132572 1411503871 1577544709 745359347.4 1082626703 1055274571 884822894.7 1148375466 957981691.1 705087370.6 677361150.5 903936364.8 1095284487 1354415337 907825432.8 636199210.2 561022477.2 930959001.9 598573120.5 441444634.4 646120137.1 1300613287 1297595320 1273742413 1773538865 Acetylglycine 2405794.2 578916.1 1931786.9 1872647.1 4466618.1 637094.8 1668263.5 973890.5 1335534.6 1791735.6 2036964.2 1094414 875789.1 523270 580018.6 564737.7 599199.5 1112460.9 1357758.5 4484567.1 1243219.2 2208982.8 3141775.1 4383702.1 2015518.9 3922856.5 1216322.9 1313034 579217.1 3117864.8 1094630.4 1893359.8 608127.5 667130.8 586004 1034986.4 652051.7 2047167.6 6203300.1 2130888.7 3344055.2 2786040.3 1180847.9 3694376.4 5377639.3 1497860.6 620042.8 1548414.6 2223412 1592100.2 3155968.6 1839852.8 1927393.5 2754375.2 1761662.2 2217302.6 856349.8 842937.8 2535116.9 1685303.8 1667133.2 314747.9 1194144.1 1232449.8 3165852.7 1832191.3 2372326.9 759446.7 2792287.9 1054849 3077103.1 3107512.6 1669394.4 1080670.6 2653578.4 883629 3856550.7 1146942.7 1636531 2168908 2049755.8 1311837.9 1204992.9 1615652.8 1647604.8 769151.4 910007.4 862145.8 10950586.6 1618939 1578142.8 398755.5 1099266.7 1703122.6 1869049.1 2085666.4 2039216 1705970.2 Phenylethylamine 3597970.6 5022002.1 5171366.3 5552890.6 3452003.8 5020437.5 940077.8 1549787 613576.6 2739097.2 241668.1 3190042.1 547962.3 722620.5 740724.9 523693.4 576819.8 2727999.1 4334558.3 486387.1 595083.2 422752 462373.8 715386.9 4147115.5 4247655.2 2546848.6 605945.5 452073.7 309630.6 598558.7 2303407.3 281466 296736.6 2767410.9 346266.8 0 340761.1 349381.7 178348.1 303454.8 263706.6 257268.1 2191448.7 246591.7 210921 5165649 4973563.7 2854954.3 1392361.1 3354529.5 3285472.2 878144.4 761424.3 768887 833692.2 794180.5 744110 678468.1 262515.3 732522.2 800934.3 732202.9 762691.5 852871.3 770115.8 696518.3 718078.1 746805 693695.7 730161.2 659620.6 3664717.3 3278139.7 740855.1 776334.2 13088504 2922505.8 2808016.5 798236.1 721399.3 727929.6 730459.2 738029.1 690339.2 763031.2 732532.8 682217.5 660609.5 8797134 3665697.2 1554763 1948227.9 1716567.3 3277699.2 3511094.5 3141141.8 2608153.6 Benzoic acid 3009615.4 8467038.2 7977111.9 4710121.2 4158043.6 4407871.8 4558241.9 4905108.8 8215624.6 7350975.6 4477625.7 10576425.4 5305242.7 5435930.5 7093898.3 9689793.5 9495574.6 6101465.8 3554350.6 4688106.7 7945202.3 7554396 17305424.2 6486367.3 6164358.6 5518510.1 11061939.9 8405851.4 7754777 9975961.2 5494202.2 6639571.9 9059021.4 6089557.4 6139172.3 4235343.9 6113995.9 9332509.4 3940615.5 6465688 6704335.7 5603244.4 4866116.9 7391552 4046247.5 4216079.6 5179096.2 5231508.4 4117211.6 7642797.8 5592123 4859583.2 9474098.5 11006556.3 8983659.2 9040710.3 11492497 7132002.7 8400162.4 5033643.9 7526936.6 8369484 9792292.8 4927971.4 9970306.2 4322135.1 6546541.5 7390153.4 6422420.9 5825753 9125458.4 4268384.2 4595820.7 4338281.8 8315797.8 7641658.4 4365513.6 5980067.4 5724530.3 4860069 7853028.4 6819583.6 6299692.8 4027702.3 5586277.4 10828707.4 8374737.2 3973711.9 5497055.7 2357051.8 3490219 1884957.3 1706445.7 3585069.6 5344371 6486119.9 5069586.8 6588680.7 Taurine 7931520.7 35139885.5 5584968.1 4908916.7 10669739.1 16946167.3 21088918.7 18314354.3 17352216.4 11943892.4 14249238.9 10970913.7 15890665.2 18496486.5 29152476.5 26047798.1 19505149.8 7899398.8 8982294.1 11281205.9 15652899.1 15605905.5 13243501.3 17844097.8 6697928.4 6096617.7 12943135.7 14933615 14914244.2 12375791.5 16146491.5 22314653.4 21042820 16893537.9 17826379.4 15173071 15529438.5 16328953.5 17974371.3 14376416.9 12553646.1 16859313.6 16096888.9 15621508.3 16537380.7 18005658.9 6966640.3 6808546.8 33238067 27826996.1 4871255.8 6141322.7 10939085.8 11618639 15048770.2 12912285.4 13016662.1 19683655.4 16607048.3 13296562.4 14827482.5 18221688.5 17229454.4 23861714.8 12699936.5 17865596.1 16239268 14703192.4 14635165.2 21997543.7 19343609.6 24871341.8 8236941.5 7264137 18245475.7 16883765.3 13918426 11698527.1 11077426.4 24228288 14603507.2 22720281.8 19072801.1 17513937.9 19700820.7 17674582.3 20680359.5 24288276.6 20073890.6 7571259.1 6544862.3 16682860.9 1119014 4893835.9 8298861.5 7900542 7874282.9 30604504.9 3-Methylhistamine 1890039.9 2236847.1 1731674 1705273.1 1355355 2287423.4 595833.8 4562411.9 422142.7 548962.2 4263975.2 625203.4 4044701.7 5113869.1 1029143 1520790.8 1882302.5 0 4163198.4 1929939.1 2005907.3 4349168.2 858843.1 644221.9 1968100.7 1623945.6 2557828.5 11549902.8 5307060.4 878227 3072805.7 519093.3 1389818.1 8948070.1 445487.6 1615158.8 2359305.9 904542.7 5646164.5 585939.4 7233486.4 4831262.1 919998.8 4913326.6 2648274.9 683196.3 1832971.9 1507413.9 2223396.5 1507558.8 591640.9 577958.3 7370280.1 1212418.4 1786094.2 905609 259922.5 6014845.8 6057863.5 4520413.3 1965464.9 421545.9 5794189.9 1315147.8 563209.8 2321609.6 5679611.2 4702302.3 5740956.6 6594966.1 5603471.8 5216356.4 1281520.3 1405527 3325268.2 9214880.9 425354.9 497189.2 3320118.2 3220002 4097756.7 1515596.2 5859285.2 199750.5 5834327.9 4368078.3 5662012.1 982672.7 1205812.1 1856365.6 2833467.1 1191934.7 315935.8 1079858.8 711348.3 1187615.1 956375.3 1178565.1 Quinoline 11900650.8 18622189.2 27442526.8 29554991.9 6852262.9 3791184.7 5941646.4 4921920.7 2075121.9 2874058.9 4481485.5 5581875.3 6617386 6970499.1 6176403.5 7572566.1 8989803.3 2457331.8 2496778.3 4826671.6 8499024.4 7980649.5 12209355.3 13763401 31508780.8 30078088.4 11089486.5 9695895.3 10043587.8 9612812.6 6561363.4 3910460.8 6453960.3 5757112.1 4160967.9 8467068.2 8193749.6 9719883.2 6360936.7 6046144.4 15266567 8191286.6 12922355.2 12724266.5 6930272.9 7592276.4 32678410.8 31004340.2 19792310.8 17971857 28797844.5 28462980.2 5884260.8 9919038.6 9026881.9 8887494.2 7659206.1 6184939 6633172.3 8880235.2 12427370.6 4372083.4 10339539.8 6486130.8 8999107.8 5770314.8 11399175 10790565.4 9354540.8 7845853.6 7201757.7 8250430.3 32707669 30421858.7 6909572.4 9046184.4 5821710 10219409.8 8930046.5 4831649.7 6242068.9 3778878.8 5207610.3 6329943.4 6853889.9 7005190.4 7430714.8 4126729.1 5343490.3 8513189.5 3235383.3 3823881.4 3229391.3 4855422.9 29257157.4 30421682.3 29071211.7 20646784.4 N-Acetylputrescine 2927380.1 3458173.4 2012752 3800989.7 8913205.9 1706524.8 7346595.4 9059765 6391695.4 472394.7 4485010.7 1300391 5597061.2 9957411.3 3892823.6 1682292.5 4077729.7 2682259.8 8225478 9872514.9 1585150.9 6449743.5 3199040.3 4543424.8 6797527.9 6638361.3 2971068.5 1880544.2 7379396 4238011.1 5928804.8 336025.1 7344291.4 5302299.1 3189675.2 9171123.4 4105570.5 5045357.3 5951143.5 3378885.9 4234589.8 4073676 4810691.7 3367140 8187294.1 2467842.4 6339448.3 2645999.5 4465150.1 1923303.1 2721800.7 4927008.9 3447997.6 7174340.8 3684593.3 5155164.7 5089395.6 2602383.6 2564580.1 6850870.7 7274052.4 1733389 5056244.6 4556377.8 3675537.2 7412810.4 9295400.5 8935552.1 6313155.8 5773543.2 4213254 8606704.7 4807322.7 3164522.3 6763860.5 8308487.5 5492622.9 4319617.4 6386469.8 7412354.6 7635804.5 14185575.7 4558433.2 9630291.3 8646261.2 7002953.3 6814086.6 5038251.8 2568217.6 996479.5 1086533.9 1803652.8 752969.1 1028311.4 4704638.8 2059648.1 4379151.9 2451076.7 Ornithine 465634729.5 444009678.3 289651238.7 284849800.8 243182467.8 1047097577 441769789.3 315017823.4 240850210.5 283161761.5 147392930.2 488990179.3 227497719.9 580274014.5 688419932.1 564421406.2 501680428.2 58276934.5 733808512.3 339102524.7 551348572.2 395587761 478166998.1 567318090.5 350335305.5 344495102.1 704109233.1 455161071 464174734.5 420784553 338970297.5 418278606.5 539631008.9 411351878.9 191901473.6 181692967.1 259030080.5 457496564 714314756.9 316495881.7 417695639 337079574.3 331933637.9 494770695.3 337282192.9 504579693.4 389963869 339611245.3 869515234.4 887771140 356542017 354134515.4 383327330.2 690046861.4 684782164.4 535257804.6 708555793.8 540549739.2 358707063.4 247283375.2 501654215.9 157055713.7 455989892.9 745094263.4 266397227.6 502195163.8 488867427 753858373.1 397983484.3 513389292 287593744.9 629296864 419653318.7 398087913.8 655175946.2 367244918.5 154372232.6 347154974.1 346689271.8 335911624.3 374151117.5 243309828.9 221239084.9 150385904.8 209932198.2 422122344.6 589073298.7 320032180.8 180480189.7 261849221.9 230833643.2 153327387.8 147790559.9 285024772.6 460743697.9 448009897.5 449844564.2 720905450.6 Homocysteine 2776322.1 3144439.6 2305801.7 2186516 1077513.8 0 1438881.8 1492843.4 901921 913245.8 1182253.8 806961.3 2173860.2 1843468.1 1335404.9 1654525.8 969965.2 484853 963067 974815.4 632112 2438270.3 815456.8 1557763.7 2277401.1 2537821.3 1003064.5 3818715.4 1161807.5 842451.3 1335084.9 1146170.8 950934.5 1162392.9 757664.4 831985.8 8179331.6 6445237.6 1177551.4 1338334 932469.5 651783.7 865339.2 2036647.9 4812136.5 1208758.8 2526882.3 2641875.1 3207585.7 3104981.3 2634931 2718055.5 1570305.2 870316.2 1430208.3 1842046.6 855295.1 1252656.8 601218.8 1190896.5 1261638.6 755663.2 1371424.5 770740.3 983767.4 2010149.6 1580612.8 1740654.5 0 2537705.9 1081466.8 0 7708069.6 287581 2539964.6 729698.6 1632754.3 1128391.4 1564302.6 2155185.3 2494477.3 1255527.1 1183684.5 1701648.9 655006.2 960596.6 1763789.7 6878917.4 513954.2 494290.8 980207.2 559018.5 288189 2619573.7 2647708 2600550.5 2116963.4 3331145.4 Hypoxanthine 78022806.2 832614510.6 40899743.8 41356604.7 370994037.1 94122583.7 4748955199 4403739250 107389869.4 103645285 262152939.6 92344677.6 490412398.9 418046066.4 3332571168 3652966722 3829261567 193664400.2 262767719.2 857724600.6 5953675746 630813943.8 755949834.3 3133108443 39827071.8 38079852.8 291978479.7 624683762.2 351897258.8 484775886.3 300227334.8 2655397209 3501251163 704539720 241472862.4 422726418.4 863421577.2 291534838.6 5084322106 2119960237 457981360.2 363648139.3 385560767.5 473297073.5 235789532.9 825870808.7 39641373.3 37862026.3 1130547171 1212320176 97551907.7 97058043.7 451983051.8 220061108.5 696974114.1 659251275.6 3166043944 3478476461 604657405.4 672604883.9 407457786.3 80853406.3 2608017763 6007955678 510721960.5 4683080540 531322730.4 410898508.6 852503698.6 935464831.2 424217210.6 4500833571 98504488.4 97319446 6291088914 914092591 166021119.7 104872028.8 101652288.6 639120920.3 737008637.5 489120689.4 722134373.1 458249718 894655082.1 973802114.8 1395837712 763694234 483308985.5 88075083.7 73973582.5 102606678.2 88818807.1 59498417.6 95521728.9 95780848 96291806.5 1240286727 Glutamine 4706072226 2203916164 3009512745 2978336198 3798575952 375312440.2 7745816689 6131358579 2265017304 605296996.5 5557096712 742942327.5 5931164561 5889462188 5912840868 6597249798 6114127088 462801386.4 4998428894 6807206225 4471819968 5395046895 8547337374 6334615644 3324368965 3256546222 7581057371 6049368948 5615646748 6311528638 5263041781 712732417.7 7113029487 6959467261 388569059 5787693447 4389408733 5553305873 5694602773 5135297345 6041097439 6199204194 5594896771 6876357405 6648091559 5055459018 3463327235 3349555602 2511839178 1828031458 2652263799 2539662299 5539846726 5125896794 7788119091 7292532281 7920853305 5807170746 4660033461 4915158835 5585758618 0 4756375475 5638400990 5422447942 6321962012 6181693050 7940649960 5896348966 7708068856 4635465205 6360715590 2737933743 2718700555 7675111145 6504336246 6185885291 6044353729 5251349846 6406814243 6877106833 6037590968 5917973188 4624164699 6152094073 4636095633 8748487650 6229029312 5218818348 2327000934 2258529923 1605844478 1632603480 1949598901 2872314712 2981826712 2968077479 1550297167 Lysine 992248295.7 835648585.3 731422836.1 750617611.7 731233074.2 2058236839 962320440.2 596633355.4 810464142.9 808194897.1 582256257.7 1823039803 645430726.2 842440034.3 1051001435 1184451596 1340972103 309724894.7 519673793.8 755128917.6 698873753.3 761704359.5 1397432781 1042502300 884967016.1 851190835.3 2001109190 1038996315 1167415662 1191443157 709146410.4 1205749219 1333116951 973999858.5 486144771.2 691174264.6 765596616.8 1815179413 874538319.8 760743659.9 1158886963 794735139.2 908019847.8 1141507253 889099105.8 874304453.1 959253629.1 934491549.6 1333870731 1532237918 893158327.4 872190415.9 744972222.1 1378497508 1650998301 1405602695 999548155.5 1119186575 762526140.1 873269824.5 1139757945 498912305.9 1273515792 935600299.6 919380331.1 739433508.2 1405571526 1491627817 862436002.1 1100932219 1200083414 1372752366 997048336.8 1028316055 1178377248 1137385310 572011989.3 1039891022 984909795.1 563946721.4 843849501.1 684428602.1 751034318.7 477556041.2 710598683.1 860844296.4 1202854096 324567749.7 551365548.5 615532613.7 369056537.3 408359962.9 257252717.7 538837537.8 1172205828 1090490228 1131849458 1277093405 Glutamic acid 290776832.9 1346462784 481869102.6 472924641.6 215263106.8 923859818.3 627986870.4 380668413.3 829861545.1 1469254845 359215439.6 2325805094 327068920.5 438464297.4 390586428.5 350562216.8 401668020.9 524484141.6 256130751.8 204136003.5 311121529.4 316651413.6 171170043.1 317516569.5 523743013.2 509332518.4 213684973.9 300780075.2 202948388.4 284178956.7 240934134.3 1955571142 442594001.4 432265060.8 1134756254 226115993.1 243174867 237046052.5 349101192.3 291524560.9 290700146 231504244.9 237415682.3 244041649.8 311739198.3 266657772.2 578935078.7 563452674.4 1514294946 2062197851 681138435 672714368.2 103499866.9 194494723.5 309497599.7 119403247.5 229940431.1 305086366.1 495781151.4 247869740.9 230345378.9 1058515803 277954168.9 395121419.6 232903850.9 471931495.3 555504137.3 490412721.4 442632627.3 675824640.6 290327247 596812668.2 822952645.9 876882862.5 517285621.7 291834044.1 302357601 316872102.4 367312923.2 358684746.2 258137046.7 194920622.5 351118766.1 218680343.6 328416356.9 330821773.9 539602711.6 292651847.4 238489812 56172834.3 0 103420831.3 0 0 943038538.4 876088995.7 820224228.5 1808301333 Methionine 181140900.5 133604779.9 126182387 137069589.3 123661867.8 6486581.4 182552389.2 140947706.3 33765189.9 85310760.7 129025286.2 185061403.4 95853724.7 149277166.9 186022065.9 253844023.6 208875616.8 87730171 99269555.5 230760111.7 104490102.5 168039719.1 399814748.4 140483464.1 142698681.1 147777108.1 354084678.6 219060599.2 204628663.8 256188054.1 126410545.9 87230083 225526632.3 291653377.9 71289514.6 126094113.8 109529773.2 322064153.4 103494894.5 112995510.6 173223571.3 141253155 115758248.6 195733122.3 135311086.7 117869078.9 136634196.7 137732463.7 122927410.1 117941371.3 136981233.9 134972741.3 133276526.3 290478353.7 286787255.6 292732685.5 287893472.9 254090000.6 193215510 87328873.3 184965610.6 86348046 229753343.4 102155088.5 225597467.8 94499459.4 266467020.5 260912668.3 164658425.9 172856445.7 295350547.6 115336894.3 113398758.5 108667388.4 188751723.1 204389516.1 67724852.5 80122427.2 105869402.7 125286518.4 155215208.9 251146933.9 95129420.8 143105507.6 143169787.1 236681479.5 222275516.2 120059549.3 104872773 83169705.2 49451624.1 41601097.5 40946402.4 56261108.6 132701064.8 133809811.7 131233932.2 104864131 Guanine 916115.9 1989539.4 629752 1639636.9 1885720.4 0 0 2211557.4 3585203.8 893699.1 1403889.6 824741.2 1251767.2 0 2383391.8 431527 3420509.5 558441.8 1422585.3 0 4443284.7 0 0 0 863274 707085.2 321986.6 410196.3 3400522.2 468642.8 0 0 0 2619430.9 245746.8 2564787.1 5228351 0 0 488402.3 585953.6 0 406780.1 7242551.2 440225.8 0 696102.7 2046784.9 853920.5 563946.3 452039.2 530167.3 2828355.2 0 6809416.2 4787593.8 2410986.3 6197651.8 0 4983725.3 1371582.5 575958.7 0 2760232.9 2568472.2 0 2383224.4 0 1791821.9 1154823.9 2422971.1 0 401201.2 532684.7 0 4919979.3 499021.7 449731.2 2847908.5 0 1304475.1 2921047.5 387802.7 905517.3 2798162.4 1408366.6 1053875.8 0 1186665.6 0 0 0 0 0 562263.8 496086.4 534284.7 673687.6 24-Dihydroxyacetophenone 1374273.3 1688510.7 1621189.1 1267152.5 931299.3 1151647 1168138 1150602.3 1085141.4 1044960.7 1392602.2 1082278.6 1136104 999800.8 970526.7 1011535.9 946768.5 1031571.7 1363933.2 1108764.6 1055973.5 791192.4 1106795.7 1159261.5 1192891.1 1106373.7 1169469.6 1094326.7 1224297.2 1033242.2 1065286.5 1109824.9 1170666.1 1079475 927211.9 1194219.6 1074073.6 1099080.4 1108282.2 1031346.1 1141548 1150210.4 1256153.3 1134406.5 1186462.7 1161964.3 1057940.2 982820.1 1322967.6 1127811 1122493.9 1099651 1265633.8 1104783 1064072.4 971518.8 971384.1 1056640.2 1177207.5 1134659.9 1028829.9 955772.8 1017764.6 1111970.1 995145.5 1120627.8 1036258.2 1058693.2 1068411.9 1042973.4 1215892.3 1044000.4 1150575.4 1035233.2 969346.6 1147070.1 1374921.6 1395209.6 1282601.5 1216792.4 1086222.5 1038989.4 1327529.6 1190048.8 1184727.9 1031062.2 1227448 758638.1 1058459.7 1733752.8 1199521.4 1429563.6 1505913.9 1273360.5 1180387.3 1010970.9 1143094.8 1262796 3-Sulfinoalanine 0 0 0 0 0 0 193390.8 318861.9 1893378.5 366362.6 253612.9 693034.9 743902.4 838091 451637.4 283241.7 382717.7 0 582829.6 0 208193.4 0 169439.8 738233.3 0 0 683759.3 186494.6 301749 324957.8 0 409177.2 1276602.7 430451.2 373574.3 165827.1 0 397426.5 569654.1 0 234396 306913.6 402655.3 380148.7 591261.6 0 0 0 0 812159.2 0 0 407646.6 446250 273266.4 0 0 0 2291774 238037.9 0 0 0 430218.6 271129.4 308193.4 396142.8 451424.9 0 318090.3 0 0 0 0 348461.3 432396.3 0 0 0 330768.6 226581.5 0 0 0 383452.9 0 0 0 527545.2 0 0 0 0 0 0 0 0 0 p-Octopamine 2263223.1 2688805.4 3169947.8 1376054 2515935 1699881.8 2364998.4 1931841.9 2180182.8 2046634.9 2006342.8 1895683 1899287.2 1796753.8 2639735.2 1437995.2 2035627.5 2004712.7 1944618.6 3138909.2 1798458.3 1919742.2 1967857.2 2020332.2 1252493.7 3383196.9 2234294.5 2294903.5 2420625.2 2129352.1 2229483.1 1556875.5 2606822.3 1994019.7 2874040.7 2115270.6 2499106.1 1865984.3 2034205.5 2413336.9 2109073.5 2012417.3 2091393.3 2074978.5 2013532.5 2051867 1358687.2 1622480 2972914.1 2230127.3 3474638.4 1919699.7 2405463.5 1213320.9 2100847.3 2235442.3 2107053.8 1931916.1 1491712.1 2157654.9 2207334.8 1656555.8 2088788.6 1892998.8 1892367.9 2141113.5 2142451.3 2024004.4 2157742.1 1821099.7 2303270.4 2023523.8 3473800.6 1251121.3 2332729.5 2166152 2224714 2074460.8 2282709.2 2456232.6 2447532.4 2409957.5 2364912.5 2077967.6 2246720.7 2189869.4 1877348.9 2084064.6 2006584.4 3594534.4 2649146.5 2115129.7 2105362.5 2221319.4 3088617.6 1239565.5 2785705.5 2271597.7 Histidine 2319532830 2306634765 1794272050 1797724322 1694682267 199434563.2 2795339570 2211371574 867533904.6 869827381 2200788585 1259839597 2468535940 2745368565 2886119784 3476083087 2975936571 476822476.9 2036955977 2452500652 1698845144 2653946196 3859909044 2609679427 2076479016 2037609717 3823235337 3034083818 3559956332 3235225073 2462282535 892542551.9 2992430962 3041831446 868034712.5 2268234349 2172335445 3048818507 2382368423 2417534937 2784015952 2505908891 2708428678 2819660354 2281774955 2729138253 2235226284 2120218113 3265758425 3181981487 1861334952 1794065619 2301173860 2732840926 4332981278 3401263408 2918238425 2968903045 2351868829 1988486219 2677625260 454865421.4 3587219018 2594585533 2351139938 2532329215 3046247640 3207684744 1969989860 3083830072 2438662796 2990173724 2165006515 1923511789 3452203107 2158357834 2712279795 2372124607 2514466538 2148984165 2727416168 2567137288 2083454960 2079699172 2089622216 2283624061 2877255629 1880068335 2263020307 986036452.7 697464637.9 882563814.7 705037264.7 772145199.7 2300094678 2248941737 2259573952 2999602255 Allantoin 0 886383.3 2803875.6 3388887.4 2669626.3 0 0 0 0 0 0 0 0 0 0 0 0 0 9133072 0 0 0 0 0 3680950.2 2697468 0 0 2412528 2001992.7 1716421.2 0 0 0 0 0 0 3202600.6 0 0 0 2580930.4 0 0 0 2765469.5 3568486.9 3836051.7 3701300 4464267.5 2989788.3 2632927.8 2731915.4 3156281.5 0 12603115.3 0 0 0 0 0 0 3258989.7 0 0 0 2136302.5 5817449.5 0 0 0 0 2336922.5 1676721.1 0 0 0 0 0 0 0 0 0 0 0 0 0 3196364 0 0 0 0 0 0 2649265.9 2353342.6 2872733.8 1818583.6 Indoleacetaldehyde 0 1744752.2 0 0 172122971.2 3425487.1 115785993.9 112603828.1 0 3660566.5 63611710 20157029.7 104801844.4 33062081.4 58148948.2 42829359.5 51824555 16871507.2 30373976.9 183227642.9 103635545.6 176572157.2 198987667.9 85878636.7 0 0 118562478.3 218548326.8 77042006 136396147.6 50955455.7 2992598.1 92454838.6 123015754.5 4030347.2 86478376.2 117306229 101308848 42286886.6 50672421.9 160083660.3 181044365.8 104077806.1 175373343.8 58486057.5 133188854.8 687273 0 1262712.1 1559512.2 1556509.3 6569382.2 171737275.6 43383414.8 154463223.9 45480654.1 14926744.5 89675730.3 100514241.5 138267518.5 136114396.9 10794515.3 77788712.6 53396434.4 118310462.8 106635571.3 165789923 63710119.8 152909545.7 173693525 181330323.9 113983686.8 1707201.5 1732780.3 78486670.6 231053884.5 6273505.3 5550026.5 11007538.1 49567547.2 94659478.8 104147298.5 117113632.8 51685501.7 138030612.2 78271896.5 72840716 49487271.6 120317383 1769790.3 1604689.2 1568324 1334378.5 1656658.2 1611852.1 1632537.6 1557851.7 2774550.6 Phenylpyruvic acid 15124373 22332560.6 22014716.4 23195824.2 24177371.1 16988108.1 21408103.4 21724634.2 29392879.8 28245056.4 19925412.9 39836328.3 26565577.1 24004024.2 32681019.5 41123600.8 37378972.3 23479778.6 18659560.7 23294943 35368238.8 31196184.8 60279009.7 30554015.1 25050259.3 24904060.6 40233148.8 34727606 30781258.8 37087244 23937035.5 24759122.7 35701061.8 27248168 24141021 21938695 29248647.1 33847955.6 19704314.3 26825831.6 28953584.9 25778277.6 23436065.4 29714365 22872635.7 21246597.8 25280441.5 25213413.7 20716387.1 30578988.6 22489075.3 22592381.7 31539141.7 42062027.5 36494143.5 33175940.2 42439746.6 32724133 32871485.1 25737586.6 30190994.2 28917424.4 35307124.3 26060114.3 37586220 19431671.3 29869781.2 33351038.9 25782867.8 27487914.8 38735463.8 23053702.3 22194911.3 21783805 34198047.8 33390600.3 19709888.8 29294623.5 29703912.1 23906854.8 25834408 28121519.3 23657658.9 21393551 23785137.7 36061411.7 34489402.7 17079781.7 22989836.3 13405565.1 16036559.5 12143984.1 11709635.8 19176778.2 24732086.7 24899762.1 23019623.2 27404131.3 Phenylalanine 3333301510 3431054763 3336207619 3245691490 3589360047 584648985.8 5204016482 4332474014 2286903412 1102003382 3447782760 2204755117 3859785989 4257900788 6389400457 6446112106 6029254254 1229151085 6225829485 3307251305 5294794638 5487716410 6408833802 4511863557 3419450350 3400259173 6547634313 5949712268 6176649469 5925714300 4107033586 1701916012 5427655858 4967505537 1121020833 3410191019 4372829047 6469397840 4520719091 4609893038 4375045446 3497357229 4302956487 4645845916 4475504408 4059291782 3261113520 3228829670 4194940395 4073847258 3408017374 3291510711 4972579409 5872589407 6659579398 7418020232 6631853965 4995048426 5868637884 3462454728 4789636726 1900448906 7220006633 4794250714 4042326169 3456693673 4237936797 4675645563 4117463057 3741820918 6190220262 7428379051 3387756770 3286548335 6176408396 4481547229 2564896067 3094034929 2791393088 3460524427 3048397093 3336757630 3229339244 3322957599 3459858257 4992208966 3848626529 2302848321 3522260351 2405873061 1979921033 1931422656 1435650697 1756114715 3407833590 3424916693 3471471942 4236170633 Pyridoxal 1481483.6 1885563.1 1366035.9 1276214 1578050.8 926541.8 3709084.6 3244062.1 1451410.9 2156987 1197727 2135835 1343779.5 1445804.8 1577106.4 1666486.9 1757222.5 2674338.7 1627509.5 1269367.4 1082179.3 1825134.9 1778597.3 1258445.9 1302103.8 1335911.2 3799589.5 1327894.9 2024003.4 2140855.6 2249882.2 1446339.6 1741960.8 2107499 2904963.2 944457.9 2526793.5 1770842.4 1767470.4 1295849.4 2520952.7 818754.3 1106575.2 1573546.4 1523919.6 1001694.2 1135428.7 1296976.5 1476323 1106022.8 1316052.4 1310521 1669806.6 1971837.3 1222003.6 1737480.2 1652416.8 1271713.8 1713011.4 3209795.9 1210505.8 1240847 1119494.7 1161392.3 1823465.1 862478.7 3041529.2 2496085.9 4415963.1 1968174.6 2210998.1 2377747.7 1442692.6 1241887.2 1307526.1 3806612.2 2757552 2764198 3626245.2 1325038.9 1439206.4 1938041.7 1899214.4 1170810.6 1220270.6 1239431.1 2163452 1172432.4 1458496.7 2575424.3 1413314.5 1462588.7 1277549.7 1339300.8 1295389.8 1187447.4 1334971.1 1153808.2 Uric acid 20643998.2 13000492.6 4557521.9 9804239.1 16131429.8 6410130.7 11087822.5 15090462.8 5158951.2 7751898.7 19231116.9 11772128.6 23597333.7 9547706 18822035.2 22267787.6 23898012.1 6948167.6 3197000.3 26405908.6 16086309.4 5989096.4 15463167.3 6343874.5 9074747.3 5020223.8 3718507 13085058.1 5349559.8 5184953.1 25360357.1 8474739.3 18181378.9 21630018.1 9596854.1 14949858.7 24334476.9 13774507.8 5944808.3 18628570.9 22093018.5 18632965.5 16325974.7 22311866.6 5805814.5 21420773.5 4684018.4 4828997 15660620.1 8978924.2 6810406.7 5736273.3 24714171.2 32138651.4 20243138.8 3526714.8 13050829.8 7615435.8 10466238.2 22628455.4 15483514.1 8773002.5 15492152.7 20721087.3 14669184.7 18293602.3 4322400.7 13162847.5 13054248 20855148.7 13728287.1 15583633.9 8805152.1 6292982.4 14426072.1 12874340.1 18082924.1 2584778.8 3897983.8 22302322.2 3722878.4 15723069.5 18794567 27195976.4 20500444.2 21751796.9 14662373.2 15196023.2 17548882.3 11375828.8 5708383.6 12285141.5 2768703.6 4478331.9 12150508.4 6431025.8 10950600.4 3378474.7 1-Methylhistidine 212900123.8 252339139.2 279009647.4 262007698.3 275686964.1 25649039 115550882.1 89503674.1 33788323.5 34591375.8 80887391 36964213.9 90055013.2 146021097.5 145582145.6 162470746.8 138188731.4 26834247.1 73209204.3 244750829.9 98461974.7 101744570.4 170010262.2 137841798.2 287716018.8 297905565.1 196982199.1 163956449.8 874144444.2 158956841.3 79243085.8 36359619.9 120483789.4 1151845536 37626205.9 88239490.3 266500020.9 99780061 92073374.4 133592553 252996379.9 105869134.4 119217264 179561353.3 232695224.6 85425504.2 300247248.3 281795050.2 323525704 433075590.9 401686580.8 378449838.8 221251977.2 377318411.6 546056782.9 380538515.3 220330972.9 45800007.7 55682813.3 75051549.8 91875814 0 75786756.8 93230755 40607452.7 84378218.5 126308957.5 118531246.8 99809860.8 155318758 43446530.4 72207548.6 409548850.2 402162775.5 69420862.7 41855464 85183940.6 44931596 72936082.2 79455315.6 48908281 99684731.7 71625306.3 169621964.2 83847808.4 33656356.4 59550181.2 50873350.8 104443347.3 537701599.3 106501185.7 237127839.7 25883074.4 12145239.7 363419358.6 409221874.3 297048326.8 380451762.8 Quinaldic acid 1226761.3 0 190628.4 1385484.6 141600 52217.4 199754.4 374609.5 303259.2 198594.5 432306.1 163116.7 196664.8 269997 404849.7 299496.7 240752.3 345721.3 433851.7 31514.9 363741.3 372470.9 279456.4 384434.5 123503.1 106552.4 162067.4 1661901 274122.1 450220.1 297831.3 230664.5 159928.8 212976.4 1615072.6 319409.5 384413 397307.7 389412.4 446079.6 490614.2 367823.4 446863.1 468954.5 1812463.1 438013.7 1237253.1 344049.7 2388069.4 1226475.2 289063.2 218630.8 277395.8 272202.2 267612.3 157472.4 273086.6 268793.3 296443.8 1823525.9 260205.3 339245 1100746.5 245030.6 1233407.2 258792.3 297045.9 265781.1 295940.9 275334.3 300309.3 278539.2 608367.8 852012.7 280155.3 1180657.8 283422.6 1060521.8 268647 293982.6 287228.1 4369720 266236.9 266864.6 232202.1 294087.3 267113.3 267932.9 1025560.3 1157480.5 826410.9 294806.2 264644 275247.2 252743.1 271544.1 1108333.4 1350489.5 Guanidinosuccinic acid 749954.8 0 0 0 0 2059546.3 0 0 734688.8 0 0 0 0 0 0 1452979 1831408.1 0 0 0 0 0 4973553 2078954.5 2209417.4 0 2219232.6 2408864.5 0 1762342.9 1413281.5 0 0 2433087.3 0 1856233.6 0 3458885.4 1900843.5 1418583.9 0 0 0 2063532 1999674.5 2372864 10172826.8 5101310.6 0 1816036.9 4587934.4 0 2349184 0 0 2336206 0 2632680.6 0 1158594.1 0 0 2420801.1 2056468.6 757828.5 0 3303670.2 1967087.9 2555944.7 2098875.7 3263562 1765451.5 0 0 0 1827952.5 0 2110553.2 2159095.6 0 0 0 0 344026.2 2359664.7 2805247.9 2362794.9 0 1591238.2 1545261.2 6387036.2 0 0 2087466.6 0 11005512.1 0 0 Indoleacetic acid 6330631.1 2767627 3650332.4 3139912.4 2016785.6 13020461.1 2246163.6 2353562.6 1132407.2 1795488.4 2140177.2 1615990.1 4062451.6 1812192.7 4473204.4 3711165 5184143.3 1128820.7 7624560.5 3362175.4 1939263.1 3140208.1 5868034.4 2264540 3912813.4 3066031.5 4430670.4 3138113.8 2657395.7 6158900.7 2310800.7 2038928.4 3332036.7 1985521.9 1643346.2 1735970.6 3313702.8 2890344.9 2283758.3 9800750.4 4229910 21024132.4 12525011 4275216.6 4577485.3 12617335.2 3309219.2 3066746 6376160.2 6375772 4032033.7 3251966.2 1886920.5 6771234.4 4859154.3 1044300.6 3951793.9 1864217.2 1589085.4 5959811.5 16539757.4 818911.7 7854290.9 2138223.6 7710115.6 978890.7 7680302.9 4425174.5 1696912.1 4055482.7 1916033.1 1533369.8 3252516.9 3139421.1 14525100.2 5838133.1 12482615.4 4101875.6 7629106.1 1327784.6 3339530.9 3229485.2 2049544.8 3336329.1 2131793.7 1431291 1310901.1 1003499.4 1980462.3 9944664.6 2089824.9 1846488.7 2098273 3481784.9 3384605.7 3360485 3386037.8 6825658 Citrulline 428842752.7 243301079.1 322484723.9 318713493.5 272192408.7 122150840.6 342961832.3 320784215.6 146330730.5 165554662.7 197973086.4 296921544.7 653881120.8 699664723.2 392075229 400022116.7 601080908.1 83363566.1 213910902.2 501833929.9 492488857 594084911.4 368298242.6 517959125.9 356886584 363939777.3 639133562.9 632523858.6 724593639 748527798.9 397105337.1 375376252.4 390933736.5 551459677.5 281585523.7 291271776 388117760.3 446529409.4 569242072.1 253681330.3 534389398.3 717336908.2 509075667.9 611583508.5 787936015.5 595207316.6 388276315.7 379761180 291845640.2 286761980 358046586.6 345178622.7 662999227.1 553530826.7 720217514 487976094.5 698676673.8 571495128.5 720866967.3 389515301.3 846805328.3 196545230.9 659031908.2 638897837.1 529222294.9 524323077.2 551573263.9 477007476 424161030 522006508 448394768.4 248287513.6 402881662.2 372889056.8 419543711.4 496619437.1 401029903.3 321768710.8 453352743.3 424276376.4 407831547.2 384637245.1 332144148.8 273695035.6 378207830.4 188184098.2 316420406.8 438013305.3 509239762.6 111818441.3 116450402.1 180093850.5 114860356.3 117980559.7 419403577.5 420703155.1 417085754.9 245457314.1 Hippuric acid 21426056.2 17702664.4 17947601.5 18457543.5 9246567.4 5350347.9 3592429.2 5993833.6 5505839.9 6463378 27857241.6 5278462.3 38094725.4 8526523.8 11574415.8 9932135.5 19125655.1 2882215.5 23346953.1 4943683.3 5661889.6 31646021.3 54208815.2 5720733.9 20189413.7 20034313.3 8137358.3 8907380.8 12462820.8 11533647 33720231.6 5132790.9 10713745.2 4120605 5865694.4 3372186 7821959.9 15895469 7236001.4 43120432.8 4027023.9 214008246.3 33646112 5746061.3 4694919.2 4396910.1 19977347.2 19964945.2 60459929.5 71927410 22605919.4 23560128.8 1072743.7 4236470.3 5170593.7 5455060.7 475824.7 58909318.6 1324336.1 22665338.8 5846410.5 1502696.6 8916137.4 4402544 25825488.2 0 10060644.3 3367751.6 3403140 4343441.2 33824936.1 27164150.7 23114724.1 23835622 7580633.4 831223.1 1602110.8 12688552.8 7528603.4 0 10346634.4 148070850.8 23463006.3 0 72813236.3 0 0 2780162.6 1176913.5 3621996.9 0 31640080.6 3222934.7 15094158.6 23993125.3 25479939.4 25475751.9 75838080.1 Glucosamine 1768617.3 3384721.3 1570636.7 1025093.1 1939787.3 1964210.4 1197673.4 4001051.6 2368060.2 2207631.3 3744006.7 1743244.5 3554518.9 1060096.6 4968124.8 3942856.8 4791674.7 1722795.7 8222974.6 1638420.9 4252400.1 4767955.2 4041875.1 8598056.2 608618.6 1829437.4 1039308.7 6431724.3 6913641.9 1671116.1 5775992.4 1705925.2 2666116.7 5751366.5 3830451.1 2480468 4630221 3797762.3 5198572.4 5173062.2 4404241.1 4398308.1 5133646.9 4413785.1 4377393.5 3594269.1 678117.5 737274.7 2106939.5 8862533.6 1437173.9 1249308.7 6704827.2 5999920.9 2395266.4 3327753.5 5709177.3 3158356.5 1870033.6 5911939.1 5055961.7 1536434.1 2455002.6 3056365.4 4985503.3 1503345.1 3238054.1 6713860.4 2955222.6 5395177.5 4679845 5440657.5 1253712.3 1334296.4 1703898 5135987.6 4427324.8 3251174.1 3585369 3566353.2 4399940.8 7317789.9 2428742.7 2924623.1 1635593.2 2011047.7 2696520.2 2169745.6 4317506.6 790444.8 924250 989781 807280.3 533316.8 1499243.1 1311185.2 1272269.1 1739275.1 (R)-Salsolinol 3083244.2 3244299.2 1611117.8 2016369.9 3290370.7 3085900.6 1761390.3 4911973.9 1746482.9 1057738.2 3460235.3 2044252.3 4033312.1 9842754.8 4394453.8 4300770.6 2438427.7 830539.6 2602702.4 3308617.1 2751046.2 1993050.2 3462696.1 2878685.3 1693409.5 2245615.7 3106857.2 1501386 3267967 1416300.7 1804338 2789184.4 3060961.6 4364817.5 2507756 1171260.3 3381280.9 3061961 1640364.7 3034052.6 3015862.6 3270147.8 2948172.4 2048344.1 3292387.4 3804365 1844010.3 1950195.8 3540715.7 3421629.3 2829669.1 1603476.6 1838055.6 4297649.7 4091939.6 2349179.6 3937136.8 3978940 5652884.8 1703089.1 4601334.9 1156839.8 3920071.8 1636549.9 2019326.5 6935467.4 3189220.1 4247711.2 4941218.2 1891238.9 2914939.6 3343565.7 1525695.8 950404.5 1412711.3 574616.5 2042171 2371015.9 1738948.8 1394551.6 3575217.3 1252007.7 1423785.4 2962013.1 2871187.1 3508673.5 2167927.1 3660714.1 2567387.6 3379935.8 2696020.2 2142079.1 2136089.4 2181122.5 3111666.9 3611095.5 1968048.5 3186529.5 Tyrosine 137102510.5 207334273.8 167899669.5 164781296 173678490.2 70329118.2 216323605.5 109114544.2 129303039.9 120500153.4 97019277.6 269501552.7 159842167.8 123917897.6 270161592.1 363154113.1 281306570.4 111460318.2 84444482.2 188761769.6 262607908.5 212290048.2 529737338 188005517.4 178838579.7 176448691.1 363055694 260255116.8 221415000.2 300653752.8 123113804.5 99105155 278723328.5 182054347.5 114446273.8 107909035.8 188684154.8 251164011.3 151575975 166245676.8 208533163 145795858.5 154915964.9 218402711.6 194750584.4 146971620 169703571.9 169545411.4 216527274.5 202567145.5 180335154 163392278.2 257410265.9 343942145.6 294633522.8 279028401.8 345349363.5 223269343.3 254055855.3 122124532.2 237065228.9 115873072.3 282422847 151146677.2 293580303.1 120531947.8 205014437.1 239515025.7 180932943.3 169964819.9 321030084.3 151934368 171635100.5 157707315.1 312548790.6 232104607.5 103661464.4 193845460 194801862.7 131016173.2 184299450.7 165520437.1 128669118.8 105908912.5 154374559.6 316504502.5 260863859.8 82963538.4 125300989.9 103800681.3 87338630.5 57026648 32156699.3 103735549.7 172325621.3 175452914.8 168952763.3 219183846.2 4-Pyridoxic acid 1032136.8 0 2971858.3 3329729.8 4031755.5 1835229.5 5223144.6 2261960.8 1209110.4 661441.5 1713423.4 2312460.9 4760319.4 0 4665969.3 2641021 7159081.7 1259749.5 11886125.4 1436999.1 3244537.7 8385903.8 2890603.1 1230990 0 4109990.5 10698904.7 3119698 7292303.8 14039209.6 3895841.3 1059136.3 3932102.1 4115261.8 1435151.3 3862361.4 5288583.8 5383159.7 4558902.4 983843.4 2619837.1 4722106.6 2922584.5 2133033.6 3674253.5 2718345.1 2683756 0 4824598.3 3086576.6 3967668.5 0 1105198.2 8226650.7 2833592 2085419 3962864.5 4804316.3 3701583.9 10726452.7 1497850.4 469490.1 4341987.7 5595223.9 3441817 4054827.2 3355508.8 1899977.7 15179312.5 949948.1 1930156.3 5365523.7 2414214.6 0 5908260.2 5288083.8 7879254.3 3469104 5977281.6 0 884301.5 3778358.4 2501872.4 2893374.9 2353128.3 1501065.3 3702769.2 5199647.7 1335395.3 3098066.6 0 1705222.4 0 0 3064035 5152453.8 0 3680624.6 Indole-3-methyl acetate 14219777.1 10258167 10696129.9 9538024.9 12795116.6 1708215.1 8534644.1 7944579.8 5001732.7 2377623.9 16019623.3 3956141.7 12652761.6 7409925.5 18359269.2 29022432.3 22502646.7 2898656.3 20104983.4 5929886 8861782.3 9642357.7 15776226.5 7585134.6 10739312.9 11081277.3 11193783 23599363 15704333.8 9423785.1 7509188.7 3788144.7 24524852.4 8864853.6 2290797.5 5247654.8 7754284.8 10208072.8 22855486.1 8372048.7 6628369.2 6025576.4 20992422.4 8874166.1 11845536 7999286.1 9111933.5 15483114.8 16032643.5 16352224.2 10985186.5 9913741 14280383.7 10458319 11306479.7 11571253.8 10844891.6 18095334.2 20964334 28227526.7 29693735.2 2707345.6 11837931.6 12261248.1 6044564.6 4236192.2 5543033 6087188.8 6754541.4 6662323 9158876.1 14024047.8 12253124 10244623 10181453.5 7065649.2 3621622.1 4182996.4 9792598.9 5728059.6 4389850.7 4478542.9 9097102.6 4011258.1 13766407.1 7908964.3 5915485.3 3112513.6 9780710 20991199.8 11533184.7 13348582.4 15328294.7 17013742.8 17699591.7 9239127.9 11843520.2 16351858.3 trans-Ferulic acid 940564.7 0 189482.5 244184 247076 383214.5 99994.3 234951.2 187399.4 280890.9 257760 256833.5 260785.2 212523.4 224639.9 288432.6 222114.4 215180.1 306858.7 203812.2 237980.6 214020.4 210970.2 263389.8 263680.3 691114.2 181560.3 209048.5 204070.3 186884.1 104719.5 185650.5 319279.1 254902.4 222123.7 233100.3 211290.9 157012 142180.6 239339.1 250487.4 198846.5 245970.4 202342.3 197979.3 208243.8 308043.4 311787.9 420149.9 625890.3 286572.3 309771.4 235659 228479.8 255864.1 263764.2 248749.7 207851.8 232146.3 232471.4 231343.1 238094.6 218603.6 193526.3 117611 220573.8 159466 214540.4 203037.6 215154.8 258629.7 236974 211184.5 292658 224014.9 248981 267013.6 178146 182732.8 226533.8 182698 177213.2 245904.7 230093.8 220880.6 263104.2 239842.2 184702 231187.3 1057427 0 219749.9 241854 238364.6 158155.7 227120.2 270536.9 209817.1 Tryptophan 2447079439 1963543201 2537669575 2483265383 3465127710 299590627.8 3391273247 2601463325 1151519831 1558705937 2307696839 2674246199 3196704258 3815217977 3736361849 4188253337 4507184074 1274175110 456411597.8 2725263366 4297345337 4063804149 5685887371 3559212824 2555982352 2529611673 5936260948 4943659057 5128332641 4335235143 3208204964 1665820009 3912591714 3204575309 1864149318 4068763177 3714477471 4825676340 3048007387 3234316951 7201611169 3493078489 3897637944 5159018522 3580630249 2961181824 2431448942 2418838963 2619192486 2179129472 2345537798 2220029743 3603988929 5041380325 5118343948 4632008155 4099523415 3876921824 3268098265 2888206325 4824360572 1837094626 6043570865 3471640745 4941802375 3480378132 5804573613 5966190636 4960675338 4336738401 3744372218 3707285548 2322998953 2265130992 4006563501 4579859032 1999268462 3584922559 2393412127 2422758485 3418742654 2505211134 2732263064 3420320534 3789092613 3761828793 3935871236 2304297725 2674844487 1571828087 886329516.6 999347287.7 633324995.4 1090558781 2266745425 2263751173 2307269657 2392220475 Lipoamide 2825852.3 2756240.3 2879385.4 2767847.1 2644370.5 2490038.4 3292379.8 2804095.8 2981621.7 3120223.6 4162862.6 4389945.7 2967620.3 3097355.9 3249190.2 3273983.3 3154615.7 2535390.7 2887866.8 3225886.9 3043331 3535603.5 3479589 3307807.6 3008889.1 2889068.6 3502333.5 3035579.5 3451428.6 2668390.2 3075670.9 3129841.6 3988271 2990826.7 2816015.1 3426835.6 3672693 3313700.7 3740389.6 3671375.3 3209298.1 3534062.1 3887458.4 3134625.2 3496398.8 3664463.3 3410161.7 2905813.2 3100465.9 2970375.9 2914804.9 2795776 3450758.3 2899804.3 2595623.3 2573428.6 2695375.4 3003465.8 3330075.8 3168913.4 3202993.8 4293393 3298358.8 3456036.2 3353093.4 2868082.8 2899913 3588894.1 3099687.7 3251119.4 3291090 4240020.1 3387320.8 3371319.7 3368894.1 3658088.2 3324758.3 3121018.7 3804289.6 3880194.5 3894194.5 2913944.7 3556372.3 3025528.1 3296516.1 3459137.5 3772209.2 3272061.1 3446734.5 3056469.8 3340801.3 3250708.6 3805615 3239292.6 3117143.2 2710008.1 2994253.6 3106541.1 N-Acetyl-L-phenylalanine 1207606.5 348115.1 1116770.9 859519 769416.7 3711681.3 467086.9 741704.4 291839.5 281510.9 651031.6 371916.1 390275.1 447622.2 391099.3 396734 435780.1 447573 291704.6 1641673.4 413526.9 430334.8 419498.8 462379.2 1424938.9 1633450.4 5861104.8 414289.1 484378.6 431247.9 421204 348466.2 85452.2 438541.8 300577.4 402486.5 441141.3 533213.7 415939.7 7987633 552708.4 430383 451750.9 426265 346947.3 367428.9 1486887.8 1607650.9 477444.4 371401.7 1235657.2 1676189.4 244729.2 289472.8 287408.6 366277 359837.6 233691.1 228812.1 358970.9 303192.9 133263.4 328496.8 364990.6 294278.1 416589.1 1143281.5 400468.3 2979728.5 381690.7 311041.5 270299.2 1406237.8 1496678.8 5897244.5 347079.7 378938.4 744271.3 353332.9 361339.4 336432.4 335513.7 304827 7727579.2 307832.7 254882.6 507890.2 270449.5 327133 1997680.8 616351.2 3965755.4 549890.5 0 1336907.1 1197844 1376756.2 414292.8 Kynurenine 73479777.7 27512524.1 59243914.4 58899687.4 135689532.8 4347062.1 231963783.9 122775649.6 0 2621457.1 117147854.3 2397420.1 107537634.6 148012230.2 94844555.5 102264868.9 126252756.6 2327623 62807465.5 124252384.5 97711207.4 112040728.5 102661008.1 95844261.2 56240008.3 55446117.1 114663961.6 93625758.2 114529251.2 120488769.6 168228857.4 0 172186357.5 100488171.7 2189601.2 138712844.6 124408414.9 174945912.7 92566782 148598788.9 165964124.6 103999200.2 113217101.8 131754166.6 111199213.8 79966719.8 54301724.6 53522252.5 57451166.1 43216328.8 47625109.5 45783881.2 84799302.5 167903938 170082994.6 109588548.7 88420934.8 55310558.1 72010090.4 125096560.7 118011083.3 0 133961908.1 97127829.7 103559415.7 107918400.4 217303731.9 133631353 182077904.5 137470888.9 149796503 187902362.6 48051899.2 45450446.6 134222605.9 113220976.3 149795030.2 134820622.6 139401107.1 109321155.2 129310900.9 149931681.9 117506973.5 123350062.6 118600453.7 120397096.1 136227485.9 105658603.3 85359322.5 41770498.5 20356197.2 31866020.3 15701348 28553187.8 44112340.1 45201799.8 44585804.4 46734870.9 Dethiobiotin 1600526.6 1086592.3 1394538 1711970.1 1869413.7 140029.6 2139443.7 1857358.4 159606.2 193096 0 169475.3 2102520.6 1355312.8 1423556.1 1929204.4 1703461 170321.9 1149044.6 1905033.3 179453.6 0 1938696.6 1898411.3 934638.5 1825545.2 1758737 223900.8 2227520.7 2579719.9 1652153.1 1714755.5 1786338.5 2487714.6 2241867.5 2412200.5 1755594.1 314129.5 1407239.3 2030167.9 2628787.9 1537622.2 2050320.3 1802673.7 1901259.1 214232.4 1784571.2 1723306.5 2910860.6 1921636.5 1893257.4 1315951.1 1371124.7 1793589 2748713.1 2420456.5 2214292.3 2413540.4 1481416.2 1592040 1415450.2 391380 1861943.6 1378504.4 1332281.5 2465183.6 1897949.1 836954.7 2122275 1929237.1 1799629.8 2649100.5 865747.7 1724087.5 3130085 1614817 1331567.2 1096179.5 1685733.7 105517.5 1565773 2670890.6 2161451.6 2082748.5 2155710.1 1318565.8 1216725.5 1369843.6 74862.3 0 1465310.7 0 29026 42654.5 1576982.4 1689735.8 1720179.4 986342.2 12-Hydroxydodecanoic acid 443863.2 1655434.5 0 0 1012028.1 854201.9 1895596.1 1456879 3606485.1 790059.7 0 1347519.5 0 0 2131999.4 958436.1 0 1188373.6 0 0 0 0 0 2000881.8 0 0 732845.3 0 0 0 1608607.5 1601259.3 1065414.1 1165149.8 2089918.3 0 1587070.6 0 1254063.4 0 977586.1 1065382.2 707049 1338850.5 834532.5 2032348.3 0 0 320935.1 0 0 0 0 2126908 497061.7 0 2941566.7 1350966 1825658.3 1502057.7 0 1370258.3 0 1089952.6 472916.6 0 746762.4 1679302.4 1824781.5 2309608.7 885320 0 0 0 936480.5 0 0 957254.6 870142.4 0 2627160.6 2864476.4 581562.7 1088971.4 0 1304623.1 871932 0 956648.1 1366057.6 0 0 0 0 0 0 979771.1 0 Pantothenic acid 1535906.5 926531.5 685887.1 1319735.4 4116085.7 7157238 18379863.5 19682505.1 6206238.1 3117109.7 8464862.4 7269190.4 9211402.6 10627128.5 4883353.1 3101666.6 10095329.4 2066816.1 18162862.9 12332676 5942701.5 8876740.8 8598171.3 7182722.3 773939.8 1383906.3 19505396.6 7009095.4 9657493.1 13102811.2 10520883.9 4851223.7 24631641.9 2336538.6 4011734.7 12387607.5 9486552.7 13254130.8 12732517.3 8850044.5 4156101.2 11288155.7 9167807.7 11147987 10257432.9 6398865.3 2217426.2 1432727.5 2224462.8 2078961.1 1596838.7 1510556.7 2875182.3 4724393.8 7502868 10065960.4 7861056.8 10460762.2 10463106.1 14631015.6 6072730.7 2291355.9 8260199.5 11848504 7801427 7089008.6 14720533.8 13693321.1 26355414 16144871 12742827 18344663.7 1561169.6 4075810.9 14811640.7 14487033.7 16492539 12791298.4 12491229.8 6797649.6 6231105.3 15119973.7 10459016.2 7102326 9056329.7 7891682.1 15393771.8 14043477.3 5143412.8 2214147.7 1094583.5 316732.6 333872.2 793395.3 1361741.7 2960001.7 1848778.2 1778080.2 5-Hydroxy-L-tryptophan 0 0 0 0 0 2234062.3 3052444 0 4161495.8 2128953.5 0 1233291.6 0 0 0 2979510.8 0 1153706 0 0 0 0 5451431 0 0 0 0 0 4124843.4 0 0 2460874.8 0 0 3345605.7 0 2410933.7 2993375 3073000.2 6982065.2 3349507.5 7047298 4522852.9 4073410.9 5124537.4 5152356.4 0 0 0 0 0 0 3589955.8 1760400.2 0 0 5703020.6 2567084.8 0 2552705.2 4245900.4 2640782.9 4935280.1 3382979 1872054.2 0 3681781.4 9023348.1 5892917.8 2902385.3 4221823.2 0 0 0 0 5001776 3711021.5 3441916.2 3176724.2 1246666 3437724.1 5214222.9 2506175 4414882.4 5539137.2 2989076.9 1235123.3 4927629.8 1854252.2 4694527.7 0 2496567.1 0 3526105.5 6412100.7 0 0 3818341 Methyl jasmonate 584053.4 1596180.6 1085143.6 690859.6 1117009.6 673046.6 3377352.4 3931910.3 1703347.3 246744.4 3145454 1435765.4 2641203.9 5613259.4 4773685.1 5218897.5 4396479.7 393881.6 2795740.2 5200485.5 4627814 3417216.4 3906155.7 5435033.6 919499.9 1102245.1 2959275.8 3564771.6 3298878.7 521451 5202142.1 2352403.6 6729539.5 4289587.4 1547275.4 4310135 4918508.1 5435099.4 3623950.6 5007213.7 5415516 5879196.6 5486484.1 2786896.6 5489313.4 4371978 1905938.3 1651654.7 1852820.3 1914218.8 1634569.2 1423580.1 2847454.4 3834441.3 1191627.6 832454.3 4207810.7 5572497.6 13422274.2 3451075.7 4587513.9 1773237.3 3034992.5 4555420.7 2741424.8 5688975.6 3319944.5 2668536.5 4614477.9 3517680.2 3459531.4 5669802.5 1634510.3 2295971.8 2899757.4 1920718.9 1460766.4 1252126.9 1570161.3 4365582.3 3000787.1 3286840.9 3209702.8 3993434.3 4692127.8 4344982 4098595.2 4841653 2949956.2 3296276.2 1634214.9 1098486.4 1657120.7 1552654.6 1473703.2 1593174.4 1399685 2192610.9 Uridine 11459628 315758.2 6945084.4 6307189.2 11322922.3 6558625.2 12560623.9 13900805.6 4884638.7 5778723.4 22377858.2 8038175 19424569.1 15932911.9 6905309.5 6053800.7 10313871.1 3970899.7 9683743.8 17290228.7 6178092.2 18927954.9 7179864.8 12308767.3 5468792.4 5373192.1 5327713.9 10528671.9 11278213 9746323.5 22442267.4 6300992.9 8916572 9355295.1 10420177.7 9891409.4 9556396.9 9858885.4 9546200.3 11602854.3 11549343 13873500.3 13228780.9 14846015.2 9774037.3 27321954 5634046.1 4327197.2 5396809.3 4726208.8 5641676.4 5484499.6 7711840.6 9193590.6 8703085.5 9535969.6 7398903.2 6152635.7 8104734.8 15727163.1 9580145 6409915.9 8208623.4 10900630 9194193.6 12118293.7 12531489.6 18476555.9 15671845.1 17025225.5 9967901.9 12274157.7 5816143.5 5905107.1 19347711.2 9831341.3 13337975.9 8100371.2 10718426 14160201.3 14789936.5 21539163 16961306.6 21893119.1 14641847 16341065.3 14318316.7 31101809.1 14689522.8 4292271.4 4059582.7 1836732.4 2492785.7 3908980.7 5483310.3 5088277.7 5374639.3 4999317.6 Inosine 0 14063068.3 0 0 6162939.4 4380081 225618571.4 250863297.1 26762574 26186003.6 15132969.6 26704666.3 19886609.2 7951483.7 293028540.3 153104088.7 209008716.6 22854495.4 0 14473821 591760669.9 7307625.4 22353720.2 206260365.2 0 0 7678152.3 10047706.6 9008389.1 0 6498617.1 320811132.6 132235435.7 30402904.2 21347854.8 0 8692486.4 6372030.9 444850917 64343662.2 31161909.8 13798145 6494004.7 10953949 8152840.1 11689751.6 0 0 21147755.4 10123750.7 0 0 19195758.9 44256.8 62156061.8 27789820 484038242.8 330388282.9 0 46875275.3 30416268.1 12848898.4 149743265 479116000.9 58036693.2 419978817.6 77374958.3 31311378.3 91355761.1 26049419.2 16575468.8 140805561.3 0 0 397098546.4 116939222.8 0 0 0 0 24052484.5 33493185.7 7464890.5 6807080.4 8075681.7 16411695.8 22018384.7 5497452.6 32881246.2 0 0 0 0 0 0 0 0 9686682.4 All-trans-retinoic acid 1190393.2 82508842.7 47518814.4 48531320.3 0 2311859.1 0 0 2274198.2 2685861.8 0 3866667.3 0 0 0 465986.9 515940.6 5060453.7 0 0 0 0 2732651.1 475138.4 55086161.7 53690400.6 1805095.8 0 0 1234436.5 0 0 0 0 5639935.8 0 10576409.4 0 0 11002114.7 0 0 0 0 559258 0 61183614.5 56697282.3 132918879.3 103540955.8 52576789.1 53612622.4 3564529.1 14418587.2 0 6608310 12213454.6 0 0 0 0 6686504 0 0 0 0 571272.3 0 2585272.7 0 0 4236964.2 66867470.5 56242442 9176023 0 0 0 0 0 0 0 0 2163702 0 0 0 0 0 3065810.7 229468.3 0 0 0 56359824.4 57486158.1 53733801 128717994.3 Sphinganine 721882.9 2514902.7 3543603.9 4390252.6 0 2271197.5 0 0 0 0 0 0 0 0 0 8520669.6 0 0 0 0 0 0 0 0 6524291.8 5922766.5 0 0 0 0 0 0 0 0 0 0 3741211.2 0 0 0 0 0 0 0 0 0 6714325.1 6167598.8 3140887.4 3610402.5 6898536.3 6362051.1 0 0 0 0 0 0 1582415.1 0 0 1092723.4 0 0 796590.5 0 0 0 0 0 0 0 6279331.8 5385014.6 0 0 1042654.3 1278741.3 1260628.8 0 0 0 0 0 0 0 0 0 0 0 0 990759.4 1038924 1015441.4 5712130.7 6449365.2 5874717.7 3624895.1 N-Acetylneuraminic acid 566466.3 1963735.4 0 0 1280168.1 999239 1556216.6 3184470.2 2262628.7 1769858.6 1079702.3 1509396.5 3669039.1 5238989.3 953863.3 979107.2 1119202.5 487923.6 1619307.3 1111349.2 1076875.1 2470510.4 986549.5 2469110 0 0 943985.6 1073460.7 951449.8 1311230 3718576.6 2133348.9 2710042.3 984611.3 2338702 2873623.9 2460424.2 1292230.9 1445583.6 982914.5 2515461.4 1501183.8 1012961.2 1134453 3267579.6 2970668.5 0 0 2131738.9 1170781.8 0 0 835623.9 883442.7 1453719.1 849524.2 0 1325578.7 991113.2 1124330.1 1069878.4 0 1061516.5 1073246.2 1612293.4 2109024.4 4110097.6 2165095 2914833.3 4355399.6 411125.2 3220054.9 0 0 1126215.2 1081474.1 3659517.1 1845868 3701804.8 0 3225237.1 3287268.4 2464269.4 2233757.4 2949108.1 1364457.3 1724677.8 2661871 2340926.5 0 0 467407.4 0 0 1686981.4 0 0 1218834.8 Dodecanoylcarnitine 29704365.7 19115350.1 29459470.8 28878676.5 7934255 4934743.9 30266248.1 32657297.4 8707262.8 10559367.7 21443643.4 13600861.8 15716839.3 55735136.2 15328734.7 20321238.8 33197095.8 6307716.1 6003018.5 12878668.5 14366833.2 8434251.2 28692165.9 26223547.8 29948341.7 29141559.9 4361072.1 8779422.7 9686324.7 13589841.5 15362291.8 14526568.3 29286650.9 58980604 33560603.5 61405498.8 6046283.6 13174583.6 23848228 25098412.4 8191490.2 25567845 4241853.4 39069370.9 32411443.5 4963354.8 31806252.4 31222465.8 21685637.6 13342972.8 22620488.6 21320094.5 14351018.1 10152199 29208041.8 13569031.9 5602472.7 1153129.3 3647636.7 3212394.1 7085579.8 16282555.2 17321256.4 23726929 1893231.7 44244370.7 28434662.2 46937821.4 19100960.9 47386948.6 9369795.7 26036375.9 26439726.7 23987335.8 28260624.1 17144602.6 34538125.3 26763952.7 65932063.8 31706282.1 35364002.3 14637148.8 37651739.3 35901457.8 13762834 18747941.7 40223101.7 21981338.6 36064885 66428176.7 34187962.7 3475816.4 22321332.1 28900673 22757351.3 24048571.2 21627331.9 15861837.9 Cortisol 14138195.1 4863950.5 14679825.3 12958886.5 13681140.1 0 8150270 11567686.9 4330039.8 601713.8 11298890.1 2749107.3 2020369.1 17807171.7 6927616.3 17176437 9064147.8 3745321.7 15240803.2 15961695 8248197.6 7842941.7 11899254.5 20972946.5 14501181.3 13550224.9 3981708.2 11679173 10922730.6 10351499.5 4550688.9 5104447.4 5092441.7 4644034 1696500.4 9476707.6 5548773 3418650.2 7952015.6 15462906.3 10255799.6 15947290 5465684.4 36925495.5 4916230.4 7411828.6 16768983.8 13934345.9 12733689.8 8991718 12681267.8 11172996 6495093.3 11425177 4138989.9 2904249.3 4253491.4 3879449.1 5108445.1 2683120.4 5180012 0 3844351.1 8091272.6 15685693.7 8071789.5 6178542.4 3085813.8 5383262.8 12353943 4348904.9 12248386.7 13411336.5 12070078 15856134.9 8938887.9 3147950.5 2823672.6 7731875.2 18854701 12448528.7 29816774.2 16488341.6 11597028.4 10332403.5 2701601.6 4762280.4 17270397.7 16508889.3 14779293.8 7313457.3 13217000 35889163.6 7920290.1 12959602.5 15455653.2 12154758.8 11325203.3 S-Adenosylhomocysteine 319153.3 0 560402.4 498091.5 301075.9 0 492303.7 417189.6 0 0 0 0 375815.5 0 0 244877.4 426200.8 0 4082431.5 504801.2 419167.6 290540.4 350057.2 0 0 0 0 720493.1 0 428432.6 0 0 690572.6 3877968.2 0 370075.5 0 0 490720.2 340156.1 0 0 0 0 0 370381.3 0 373948.3 0 0 0 267572.3 0 0 1525109 0 0 118187.8 193752.6 0 0 0 0 845583.9 3417521.3 0 0 0 3443989.8 0 0 181417.4 0 290864.2 0 0 0 0 0 0 0 0 0 0 0 0 550190.2 0 0 0 0 0 0 0 0 0 0 0 Cholic acid 0 0 0 0 2225423.1 912974.1 18355628.4 2064007.4 1750765.4 0 1916869.1 2275121.6 0 1312704.9 0 0 3311925.2 2095419.2 0 6297036.7 5098333.3 3884277.3 2742097.4 0 0 0 0 4241527.4 0 4279336.3 4102840.2 1565979.1 1959455 3532770.2 1840307.1 2647613.1 3960795.2 3947414.8 0 3374834.6 0 5126332.7 3601104.2 2967877.4 3457988.7 3086283.9 0 0 0 0 0 0 1314611.5 4496929.8 0 0 6259267 2317630.8 0 1715155 5245146 2328704.8 0 0 1173278 4507993.8 1471139.6 0 455402.2 2803653.1 0 0 0 0 3763097.9 3265152.7 0 0 153589.1 615401.4 3324171.3 2134840.1 4762310.6 3794258.5 5259634.5 6748411.5 4425343.9 9311034.9 4301519.7 0 0 0 0 0 0 0 0 0 Biliverdin 6364907.2 4931441 14921129 9936167 0 1013328.5 0 4794703.6 0 0 0 0 8078095.9 0 0 604088 7710405.9 0 1363526.3 7123150.7 0 0 0 0 10338723.7 10256452.3 0 0 0 0 0 0 0 0 0 0 3969943.8 0 1400870.1 0 4270412.4 3480408.2 4054866 8278121.1 0 0 11666049.5 9787926.3 6516542.4 7312131.6 6103440.4 11603561.5 0 2437498.9 2563363.1 0 3893067.4 0 0 4051805.7 3307982.8 0 0 0 2231390.5 0 0 0 0 0 0 0 10376450.8 12427671.2 0 0 0 0 3800244.4 6116013 4258358.2 5889335.9 3690204.2 4659735.1 3125643 0 0 3237500.7 0 3808751.8 9678194.8 877043.2 4661717.1 3622574.2 12210355.6 13356701.5 9338786.2 7662694.2 Bilirubin 192306388 14762039.7 104323941 107734915.6 125332277.5 0 115479985.1 66535547.5 0 0 111950566.7 0 109662107.5 23778567.8 127426331.4 194864950.2 375002418 0 70052932.3 179515590.3 128082367.5 129653356.1 43573794.6 137333357.9 89808525.6 82629426.2 219894145.9 62598620.4 117712801.4 90174078.6 55527120.6 0 32598128.7 130892297.6 0 35211266.2 128673193.1 86530300.1 82243676.6 213478240.1 244833154.9 157529659.1 152565863.5 158032808.6 91751417.7 115836829.9 67290124 65288923.4 79062095.4 84657377.9 91033547.5 78263829.9 160017806.4 129947435.3 168850614.9 89423010.9 243672759.4 97113347.5 70031660.4 150234240.1 109996878.8 0 63340123.3 118320989.8 164148790.3 60246953.2 57453173 89419467.3 192595432.1 81300013.7 52037055.5 71600721 57722687.4 33510563.6 85992110.2 47762840 100740086.4 32869989.9 44047975.5 348112738.2 235399556.5 371769979.5 181451981.8 209335709.7 121214855.3 74502707.5 85000606.2 96846401 180677474.3 278327711 157522068 87418539.9 84661738.3 117930038.7 64469242.8 67638559.4 62141600.4 74596317.6 MS_METABOLITE_DATA_END #METABOLITES METABOLITES_START metabolite_name chemical_ID InChiKey quantified m/z rtimes MSIcategory Adduct Benzylamine HMDB33871 InChIKey=WGQKYBSKWIADBV-UHFFFAOYSA-N 108.0808 24.9 1 M+H Hypotaurine HMDB00965 InChIKey=VVIUBCNYACGLLV-UHFFFAOYSA-N 110.027 70.5 1 M+H Histamine HMDB00870 InChIKey=NTYJJOPFIAHURM-UHFFFAOYSA-N 112.0869 85.4 1 M+H Creatinine HMDB00562 InChIKey=DDRJAANPRJIHGJ-UHFFFAOYSA-N 114.0662 42.2 1 M+H Proline HMDB00162 InChIKey=ONIBWKKTOPOVIA-BYPYZUCNSA-N 116.0706 73.7 1 M+H Acetylglycine HMDB00532 InChIKey=OKJIRPAQVSHGFK-UHFFFAOYSA-N 118.0498 33.1 1 M+H Phenylethylamine HMDB12275 InChIKey=BHHGXPLMPWCGHP-UHFFFAOYSA-N 122.0964 21.9 1 M+H Benzoic acid HMDB01870 InChIKey=WPYMKLBDIGXBTP-UHFFFAOYSA-N 123.044 60.9 1 M+H Taurine HMDB00251 InChIKey=XOAAWQZATWQOTB-UHFFFAOYSA-N 126.022 60.9 1 M+H 3-Methylhistamine HMDB01861 InChIKey=CPAGZVLINCPJEH-UHFFFAOYSA-N 126.1026 77.1 1 M+H Quinoline HMDB33731 InChIKey=SMWDFEZZVXVKRB-UHFFFAOYSA-N 130.0652 41.5 1 M+H N-Acetylputrescine HMDB02064 InChIKey=KLZGKIDSEJWEDW-UHFFFAOYSA-N 131.118 42.3 1 M+H Ornithine HMDB00214 InChIKey=AHLPHDHHMVZTML-BYPYZUCNSA-N 133.0971 100.3 1 M+H Homocysteine HMDB00742 InChIKey=FFFHZYDWPBMWHY-UHFFFAOYSA-N 136.0427 58.5 1 M+H Hypoxanthine HMDB00157 InChIKey=FDGQSTZJBFJUBT-UHFFFAOYSA-N 137.0458 45.5 1 M+H Glutamine HMDB00641 InChIKey=ZDXPYRJPNDTMRX-VKHMYHEASA-N 147.0764 76.2 1 M+H Lysine HMDB00182 InChIKey=KDXKERNSBIXSRK-YFKPBYRVSA-N 147.1128 92 1 M+H Glutamic acid HMDB00148 InChIKey=WHUUTDBJXJRKMK-VKHMYHEASA-N 148.0604 71.6 1 M+H Methionine HMDB00696 InChIKey=FFEARJCKVFRZRR-BYPYZUCNSA-N 150.0584 54.2 1 M+H Guanine HMDB00132 InChIKey=UYTPUPDQBNUYGX-UHFFFAOYSA-N 152.0567 46.8 1 M+H 24-Dihydroxyacetophenone HMDB29659 InChIKey=SULYEHHGGXARJS-UHFFFAOYSA-N 153.0546 25.2 1 M+H 3-Sulfinoalanine HMDB00996 InChIKey=WVMUCBHSEHBMKA-REOHCLBHSA-N 154.0169 115.6 1 M+H p-Octopamine HMDB04825 InChIKey=QHGUCRYDKWKLMG-QMMMGPOBSA-N 154.0862 23 1 M+H Histidine HMDB00177 InChIKey=HNDVDQJCIGZPNO-YFKPBYRVSA-N 156.0768 91.4 1 M+H Allantoin HMDB00462 InChIKey=POJWUDADGALRAB-UHFFFAOYSA-N 159.0512 49.1 1 M+H Indoleacetaldehyde HMDB01190 InChIKey=WHOOUMGHGSPMGR-UHFFFAOYSA-N 160.0757 35.6 1 M+H Phenylpyruvic acid HMDB00205 InChIKey=BTNMPGBKDVTSJY-UHFFFAOYSA-N 165.0547 59 1 M+H Phenylalanine HMDB00159 InChIKey=COLNVLDHVKWLRT-QMMMGPOBSA-N 166.0863 48.2 1 M+H Pyridoxal HMDB01545 InChIKey=RADKZDMFGJYCBB-UHFFFAOYSA-N 168.0656 29.8 1 M+H Uric acid HMDB00289 InChIKey=LEHOTFFKMJEONL-UHFFFAOYSA-N 169.0356 60.5 1 M+H 1-Methylhistidine HMDB00001 InChIKey=BRMWTNUJHUMWMS-LURJTMIESA-N 170.0923 80.5 1 M+H Quinaldic acid HMDB00842 InChIKey=LOAUVZALPPNFOQ-UHFFFAOYSA-N 174.055 23.4 1 M+H Guanidinosuccinic acid HMDB03157 InChIKey=VVHOUVWJCQOYGG-REOHCLBHSA-N 176.0663 64.1 1 M+H Indoleacetic acid HMDB00197 InChIKey=SEOVTRFCIGRIMH-UHFFFAOYSA-N 176.0707 30.7 1 M+H Citrulline HMDB00904 InChIKey=RHGKLRLOHDJJDR-BYPYZUCNSA-N 176.103 79.2 1 M+H Hippuric acid HMDB00714 InChIKey=QIAFMBKCNZACKA-UHFFFAOYSA-N 180.0655 35.7 1 M+H Glucosamine HMDB01514 InChIKey=MSWZFWKMSRAUBD-IVMDWMLBSA-N 180.0866 76.9 1 M+H (R)-Salsolinol HMDB05199 InChIKey=IBRKLUSXDYATLG-UHFFFAOYSA-N 180.1019 33.5 1 M+H Tyrosine HMDB00158 InChIKey=OUYCCCASQSFEME-QMMMGPOBSA-N 182.0812 59.2 1 M+H 4-Pyridoxic acid HMDB00017 InChIKey=HXACOUQIXZGNBF-UHFFFAOYSA-N 184.0605 41.2 1 M+H Indole-3-methyl acetate HMDB29738 InChIKey=KTHADMDGDNYQRX-UHFFFAOYSA-N 190.0863 42.8 1 M+H trans-Ferulic acid HMDB00954 InChIKey=KSEBMYQBYZTDHS-HWKANZROSA-N 195.0652 23.2 1 M+H Tryptophan HMDB00929 InChIKey=QIVBCDIJIAJPQS-VIFPVBQESA-N 205.0972 48 1 M+H Lipoamide HMDB00962 InChIKey=FCCDDURTIIUXBY-UHFFFAOYSA-N 206.0669 17.9 1 M+H N-Acetyl-L-phenylalanine HMDB00512 InChIKey=CBQJSKKFNMDLON-JTQLQIEISA-N 208.0972 28.4 1 M+H Kynurenine HMDB00684 InChIKey=YGPSJZOEDVAXAB-QMMMGPOBSA-N 209.092 49.4 1 M+H Dethiobiotin HMDB03581 InChIKey=AUTOLBMXDDTRRT-JGVFFNPUSA-N 215.1392 37 1 M+H 12-Hydroxydodecanoic acid HMDB02059 InChIKey=ZDHCZVWCTKTBRY-UHFFFAOYSA-N 217.1798 29.3 1 M+H Pantothenic acid HMDB00210 InChIKey=GHOKWGTUZJEAQD-UHFFFAOYSA-N 220.1179 35.2 1 M+H 5-Hydroxy-L-tryptophan HMDB00472 InChIKey=LDCYZAJDBXYCGN-UHFFFAOYSA-N 221.0921 55.1 1 M+H Methyl jasmonate HMDB36583 InChIKey=GEWDNTWNSAZUDX-LEPXEHPDNA-N 225.1485 29.5 1 M+H Uridine HMDB00296 InChIKey=DRTQHJPVMGBUCF-XVFCMESISA-N 245.0766 45.5 1 M+H Inosine HMDB00195 InChIKey=UGQMRVRMYYASKQ-KQYNXXCUSA-N 269.0881 48.6 1 M+H All-trans-retinoic acid HMDB01852 InChIKey=SHGAZHPCJJPHSC-YCNIQYBTSA-N 301.2162 29.5 1 M+H Sphinganine HMDB00269 InChIKey=OTKJDMGTUTTYMP-ZWKOTPCHSA-N 302.3054 31.7 1 M+H N-Acetylneuraminic acid HMDB00230 InChIKey=SQVRNKJHWKZAKO-PFQGKNLYSA-N 310.1125 72.2 1 M+H Dodecanoylcarnitine HMDB02250 InChIKey=FUJLYHJROOYKRA-QGZVFWFLSA-N 344.2797 29.4 1 M+H Cortisol HMDB00063 InChIKey=JYGXADMDTFJGBT-CZFMHFDVSA-N 363.2165 32 1 M+H S-Adenosylhomocysteine HMDB00939 InChIKey=ZJUKTBDSGOFHSH-WFMPWKQPSA-N 385.1281 78.1 1 M+H Cholic acid HMDB00619 InChIKey=BHQCQFFYRZLCQQ-OELDTZBJSA-N 409.2966 31.7 1 M+H Biliverdin HMDB01008 InChIKey=RCNSAJSGRJSBKK-YKSNQIBWSA-N 583.2543 38 1 M+H Bilirubin HMDB00054 InChIKey=BPYKTIZUTYGOLE-IFADSCNNSA-N 585.2706 40.9 1 M+H METABOLITES_END #END