#METABOLOMICS WORKBENCH bkopp20_20181010_103752 DATATRACK_ID:1538
VERSION             	1
CREATED_ON             	January 7, 2019, 1:01 pm
#PROJECT
PR:PROJECT_TITLE                 	Environmental exposures and inflammation in young children with cystic fibrosis
PR:PROJECT_TYPE                  	NIH/NIEHS 1U2CES026560-01
PR:PROJECT_SUMMARY               	Secondhand smoke exposure (SHSe) is a common environmental factor known to
PR:PROJECT_SUMMARY               	increase asthma severity and respiratory infections in children, as well disrupt
PR:PROJECT_SUMMARY               	metabolic signals and host immune responses in patients with cystic fibrosis
PR:PROJECT_SUMMARY               	(CF). This study defines biomarkers and metabolic profiles of SHSe (includes
PR:PROJECT_SUMMARY               	ENDS exposure) in the young CF population and determines how SHSe impacts
PR:PROJECT_SUMMARY               	regulation of infection, inflammation, and respiratory health.
PR:INSTITUTE                     	Emory University
PR:DEPARTMENT                    	School of Medicine
PR:LABORATORY                    	Clinical Biomarkers Laboratory
PR:LAST_NAME                     	Ma
PR:FIRST_NAME                    	Chunyu
PR:ADDRESS                       	615 Michael Street, Atlanta, GA, 30322, USA
PR:EMAIL                         	chunyu.ma@emory.edu
PR:PHONE                         	(404) 727 5091
PR:FUNDING_SOURCE                	NIEHS ES026560
PR:CONTRIBUTORS                  	Benjamin Kopp, MD
#STUDY
ST:STUDY_TITLE                   	Environmental exposures and inflammation in young children with cystic fibrosis
ST:STUDY_TYPE                    	Untargeted high-resolution mass spectrometry profiling
ST:STUDY_SUMMARY                 	Secondhand smoke exposure (SHSe) is a common environmental factor known to
ST:STUDY_SUMMARY                 	increase asthma severity and respiratory infections in children, as well disrupt
ST:STUDY_SUMMARY                 	metabolic signals and host immune responses in patients with cystic fibrosis
ST:STUDY_SUMMARY                 	(CF). This study defines biomarkers and metabolic profiles of SHSe (includes
ST:STUDY_SUMMARY                 	ENDS exposure) in the young CF population and determines how SHSe impacts
ST:STUDY_SUMMARY                 	regulation of infection, inflammation, and respiratory health.
ST:INSTITUTE                     	Emory University
ST:DEPARTMENT                    	School of Medicine
ST:LABORATORY                    	Clincal Biomarkers Laboratory
ST:LAST_NAME                     	Ma
ST:FIRST_NAME                    	Chunyu
ST:ADDRESS                       	615 Michael St. Ste 225, Atlanta, GA, 30322, USA
ST:EMAIL                         	chunyu.ma@emory.edu
ST:PHONE                         	(404) 727 5091
ST:TOTAL_SUBJECTS                	92
ST:STUDY_COMMENTS                	Both CHEAR and Clinical Biomarkers Laboratory pooled plasma samples were used
ST:STUDY_COMMENTS                	for quality control. Study specific sample pools were not created
#SUBJECT
SU:SUBJECT_TYPE                  	Plasma samples
SU:SUBJECT_SPECIES               	Homo sapiens
SU:TAXONOMY_ID                   	9606
SU:AGE_OR_AGE_RANGE              	4 months - 10 years
#SUBJECT_SAMPLE_FACTORS:         	SUBJECT(optional)[tab]SAMPLE[tab]FACTORS(NAME:VALUE pairs separated by |)[tab]Additional sample data
SUBJECT_SAMPLE_FACTORS           	Quality Control	NIST SRM 1950_1_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:-	Sample Matrix=Plasma; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Plasma; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"
SUBJECT_SAMPLE_FACTORS           	Quality Control	Q-Std Plasma pool_1a_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:-	Sample Matrix=Plasma; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Plasma; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_007,VT_180710_M351_009,VT_180710_M351_011"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	chearplasma_1a_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:-	Sample Matrix=Serum; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_013,VT_180710_M351_015,VT_180710_M351_017"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	chearplasma_1b_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:-	Sample Matrix=Serum; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_019,VT_180710_M351_021,VT_180710_M351_023"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	3_Baseline_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_025,VT_180710_M351_027,VT_180710_M351_029"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	4_Baseline_1	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:M	Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_031,VT_180710_M351_033,VT_180710_M351_035"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	5_Baseline_1	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_037,VT_180710_M351_039,VT_180710_M351_041"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	6_Baseline_1	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:M	Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_043,VT_180710_M351_045,VT_180710_M351_047"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	7_Baseline_1	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_049,VT_180710_M351_051,VT_180710_M351_053"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	8_Baseline_1	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_055,VT_180710_M351_057,VT_180710_M351_059"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	8_Visit_2_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=visit_2; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_061,VT_180710_M351_063,VT_180710_M351_065"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	9_Baseline_1	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:M	Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_067,VT_180710_M351_069,VT_180710_M351_071"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	10_Visit_2_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:M	Sample Matrix=Serum; Event Name=visit_2; CF genotype=F508 del /1898+1G>A; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_073,VT_180710_M351_075,VT_180710_M351_077"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	10_Baseline_1	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:M	Sample Matrix=Serum; Event Name=baseline; CF genotype=F508 del /1898+1G>A; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_079,VT_180710_M351_081,VT_180710_M351_083"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	11_Baseline_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=baseline; CF genotype=R74Q/R297Q; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_085,VT_180710_M351_087,VT_180710_M351_089"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	12_Baseline_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=baseline; CF genotype=R74Q/R297Q; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_091,VT_180710_M351_093,VT_180710_M351_095"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	14_Baseline_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_097,VT_180710_M351_099,VT_180710_M351_101"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	15_Baseline_1	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_103,VT_180710_M351_105,VT_180710_M351_107"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	23_Visit_2_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=visit_2; CF genotype=F508del/Unknown; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_109,VT_180710_M351_111,VT_180710_M351_113"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	25_Baseline_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:M	Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_115,VT_180710_M351_117,VT_180710_M351_119"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	26_Baseline_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, CFTR del 2,3"; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_121,VT_180710_M351_123,VT_180710_M351_125"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	27_Baseline_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:M	Sample Matrix=Serum; Event Name=baseline; CF genotype=Delta F 508/Q493X; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_127,VT_180710_M351_129,VT_180710_M351_131"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	28_Baseline_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=baseline; CF genotype=" F508del, 3849 + 10kb C>T"; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_133,VT_180710_M351_135,VT_180710_M351_137"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	29_Baseline_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/F508del; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_139,VT_180710_M351_141,VT_180710_M351_143"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	chearplasma_1c_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:-	Sample Matrix=Serum; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_145,VT_180710_M351_147,VT_180710_M351_149"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	chearplasma_1d_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:-	Sample Matrix=Serum; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_151,VT_180710_M351_153,VT_180710_M351_155"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	30_Baseline_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:M	Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/F508del; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_157,VT_180710_M351_159,VT_180710_M351_161"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	31_Baseline_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:M	Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/F508del; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_163,VT_180710_M351_165,VT_180710_M351_167"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	32_Baseline_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=baseline; CF genotype=R560T/R1158X; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_169,VT_180710_M351_171,VT_180710_M351_173"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	33_Baseline_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:M	Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/F508del; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_175,VT_180710_M351_177,VT_180710_M351_179"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	35_Visit_2_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=visit_2; CF genotype=deltaF508/G542X; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_181,VT_180710_M351_183,VT_180710_M351_185"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	35_Baseline_1	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=baseline; CF genotype=deltaF508/G542X; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_187,VT_180710_M351_189,VT_180710_M351_191"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	36_Baseline_1	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:M	Sample Matrix=Serum; Event Name=baseline; CF genotype=deltaF508 and G55.D  Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_193,VT_180710_M351_195,VT_180710_M351_197"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	37_Baseline_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:M	Sample Matrix=Serum; Event Name=baseline; CF genotype=deltaF508 and G55.D  Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_199,VT_180710_M351_201,VT_180710_M351_203"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	38_Baseline_1	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:M	Sample Matrix=Serum; Event Name=baseline; CF genotype=DeltaF508/ c.2789+5G>A]; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_205,VT_180710_M351_207,VT_180710_M351_209"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	38_Visit_2_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:M	Sample Matrix=Serum; Event Name=visit_2; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_211,VT_180710_M351_213,VT_180710_M351_215"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	42_Baseline_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:M	Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_217,VT_180710_M351_219,VT_180710_M351_221"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	43_Visit_2_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=visit_2; CF genotype=F508del/F508del; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_223,VT_180710_M351_225,VT_180710_M351_227"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	43_Baseline_1	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/F508del; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_229,VT_180710_M351_231,VT_180710_M351_233"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	44_Baseline_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:M	Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/2789+5G->A; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_235,VT_180710_M351_237,VT_180710_M351_239"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	45_Baseline_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:M	Sample Matrix=Serum; Event Name=baseline; CF genotype=621+1G>T/Delta F508; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_241,VT_180710_M351_243,VT_180710_M351_245"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	47_Baseline_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:M	Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_247,VT_180710_M351_249,VT_180710_M351_251"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	49_Baseline_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=baseline; CF genotype=l507del/2622+1G>A; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_253,VT_180710_M351_255,VT_180710_M351_257"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	50_Baseline_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/F508del; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_259,VT_180710_M351_261,VT_180710_M351_263"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	51_Baseline_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_265,VT_180710_M351_267,VT_180710_M351_269"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	52_Baseline_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_271,VT_180710_M351_273,VT_180710_M351_275"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	chearplasma_1e_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:-	Sample Matrix=Serum; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_277,VT_180710_M351_279,VT_180710_M351_281"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	chearplasma_1f_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:-	Sample Matrix=Serum; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_283,VT_180710_M351_285,VT_180710_M351_287"
SUBJECT_SAMPLE_FACTORS           	Quality Control	Q-Std Plasma pool_1b_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:-	Sample Matrix=Plasma; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Plasma; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_289,VT_180710_M351_291,VT_180710_M351_293"
SUBJECT_SAMPLE_FACTORS           	Quality Control	Q-Std Plasma pool_2a_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:-	Sample Matrix=Plasma; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Plasma; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_001,VT_180711_M351_003,VT_180711_M351_005"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	chearplasma_2a_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:-	Sample Matrix=Serum; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_007,VT_180711_M351_009,VT_180711_M351_011"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	chearplasma_2b_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:-	Sample Matrix=Serum; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_013,VT_180711_M351_015,VT_180711_M351_017"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	54_Baseline_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:M	Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/F508del; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_019,VT_180711_M351_021,VT_180711_M351_023"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	55_Baseline_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:M	Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/F508del; Volume (uL)=160; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_025,VT_180711_M351_027,VT_180711_M351_029"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	58_Baseline_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/F508del; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_031,VT_180711_M351_033,VT_180711_M351_035"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	59_Baseline_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/F508del; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_037,VT_180711_M351_039,VT_180711_M351_041"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	60_Baseline_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:M	Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/F508del; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_043,VT_180711_M351_045,VT_180711_M351_047"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	61_Baseline_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/F508del; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_049,VT_180711_M351_051,VT_180711_M351_053"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	63_Baseline_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:M	Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/F508del; Volume (uL)=180; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_055,VT_180711_M351_057,VT_180711_M351_059"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	64_Baseline_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:M	Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/ 2184delA); Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_061,VT_180711_M351_063,VT_180711_M351_065"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	65_Baseline_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=baseline; CF genotype="deltaF508, R 553X"; Volume (uL)=180; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_067,VT_180711_M351_069,VT_180711_M351_071"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	67_Baseline_1	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:M	Sample Matrix=Serum; Event Name=baseline; CF genotype=deltaF508/Y1092X; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_073,VT_180711_M351_075,VT_180711_M351_077"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	67_Visit_2_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:M	Sample Matrix=Serum; Event Name=visit_2; CF genotype=deltaF508/Y1092X; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_079,VT_180711_M351_081,VT_180711_M351_083"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	68_Baseline_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=baseline; CF genotype="Delta F508,  p.S489X "; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_085,VT_180711_M351_087,VT_180711_M351_089"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	69_Baseline_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_091,VT_180711_M351_093,VT_180711_M351_095"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	71_Baseline_1	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=baseline; CF genotype=F4508del/ R117H (5T/9T; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_097,VT_180711_M351_099,VT_180711_M351_101"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	72_Baseline_1	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=baseline; CF genotype=R553X/DeltaF508.; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_103,VT_180711_M351_105,VT_180711_M351_107"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	73_Baseline_1	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=baseline; CF genotype=F508Del/F508Del; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_109,VT_180711_M351_111,VT_180711_M351_113"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	74_Baseline_1	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_115,VT_180711_M351_117,VT_180711_M351_119"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	75_Baseline_1	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:M	Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=165; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_121,VT_180711_M351_123,VT_180711_M351_125"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	76_Baseline_1	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:M	Sample Matrix=Serum; Event Name=baseline; CF genotype=deltaF508 and 621+1G>T; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_127,VT_180711_M351_129,VT_180711_M351_131"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	78_Baseline_1	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:M	Sample Matrix=Serum; Event Name=baseline; CF genotype=R1162X/E193X; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_133,VT_180711_M351_135,VT_180711_M351_137"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	chearplasma_2c_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:-	Sample Matrix=Serum; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_139,VT_180711_M351_141,VT_180711_M351_143"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	chearplasma_2d_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:-	Sample Matrix=Serum; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_145,VT_180711_M351_147,VT_180711_M351_149"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	79_Baseline_1	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/R785/S1235R; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_151,VT_180711_M351_153,VT_180711_M351_155"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	80_Baseline_1	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/F508del; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_157,VT_180711_M351_159,VT_180711_M351_161"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	ncH_001_1	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:M	Sample Matrix=Serum; Event Name=nch_001; CF genotype=F508del/3120+1G>A; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_163,VT_180711_M351_165,VT_180711_M351_167"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	NCH_002_1	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:M	Sample Matrix=Serum; Event Name=nch_002; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_169,VT_180711_M351_171,VT_180711_M351_173"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	NCH_003_1	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:M	Sample Matrix=Serum; Event Name=nch_003; CF genotype="F508del, Y1092X"; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_175,VT_180711_M351_177,VT_180711_M351_179"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	hc_7_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:M	Sample Matrix=Serum; Event Name=hc_7; CF genotype=-; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_181,VT_180711_M351_183,VT_180711_M351_185"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	hc_12_1	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:M	Sample Matrix=Serum; Event Name=hc_12; CF genotype=-; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_187,VT_180711_M351_189,VT_180711_M351_191"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	hc_15_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:M	Sample Matrix=Serum; Event Name=hc_15; CF genotype=-; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_193,VT_180711_M351_195,VT_180711_M351_197"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	hc_30_1	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:M	Sample Matrix=Serum; Event Name=hc_30; CF genotype=-; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_199,VT_180711_M351_201,VT_180711_M351_203"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	hc_31_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:M	Sample Matrix=Serum; Event Name=hc_31; CF genotype=-; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_205,VT_180711_M351_207,VT_180711_M351_209"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	hc_32_1	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:M	Sample Matrix=Serum; Event Name=hc_32; CF genotype=-; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_211,VT_180711_M351_213,VT_180711_M351_215"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	hc_48_1	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:F	Sample Matrix=Serum; Event Name=hc_48; CF genotype=-; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_217,VT_180711_M351_219,VT_180711_M351_221"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	hc_60_1	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:F	Sample Matrix=Serum; Event Name=hc_60; CF genotype=-; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_223,VT_180711_M351_225,VT_180711_M351_227"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	hc_62_1	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:M	Sample Matrix=Serum; Event Name=hc_62; CF genotype=-; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_229,VT_180711_M351_231,VT_180711_M351_233"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	hc_64_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:M	Sample Matrix=Serum; Event Name=hc_64; CF genotype=-; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_235,VT_180711_M351_237,VT_180711_M351_239"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	ncf_106_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:M	Sample Matrix=Serum; Event Name=ncf_106; CF genotype=-; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_241,VT_180711_M351_243,VT_180711_M351_245"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	NCF_108_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:F	Sample Matrix=Serum; Event Name=ncf_108; CF genotype=-; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_247,VT_180711_M351_249,VT_180711_M351_251"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	ncf_110_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:F	Sample Matrix=Serum; Event Name=ncf_110; CF genotype=-; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_253,VT_180711_M351_255,VT_180711_M351_257"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	ncf_112_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:F	Sample Matrix=Serum; Event Name=ncf_112; CF genotype=-; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_259,VT_180711_M351_261,VT_180711_M351_263"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	ncf_114_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:F	Sample Matrix=Serum; Event Name=ncf_114; CF genotype=-; Volume (uL)=200; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_265,VT_180711_M351_267,VT_180711_M351_269"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	chearplasma_2e_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:-	Sample Matrix=Serum; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_271,VT_180711_M351_273,VT_180711_M351_275"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	chearplasma_2f_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:-	Sample Matrix=Serum; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_277,VT_180711_M351_279,VT_180711_M351_281"
SUBJECT_SAMPLE_FACTORS           	Quality Control	Q-Std Plasma pool_2b_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:-	Sample Matrix=Plasma; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Plasma; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_283,VT_180711_M351_285,VT_180711_M351_287"
SUBJECT_SAMPLE_FACTORS           	Quality Control	NIST SRM 1950_2_1	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:-	Sample Matrix=Plasma; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: HILICpos; Date Analyzed->10523=Date Analyzed->10523; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Plasma; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_289,VT_180711_M351_291,VT_180711_M351_293"
SUBJECT_SAMPLE_FACTORS           	Quality Control	NIST SRM 1950_1_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:-	Sample Matrix=Plasma; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Plasma; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_002,VT_180710_M351_004,VT_180710_M351_006"
SUBJECT_SAMPLE_FACTORS           	Quality Control	Q-Std Plasma pool_1a_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:-	Sample Matrix=Plasma; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Plasma; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_008,VT_180710_M351_010,VT_180710_M351_012"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	chearplasma_1a_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:-	Sample Matrix=Serum; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_014,VT_180710_M351_016,VT_180710_M351_018"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	chearplasma_1b_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:-	Sample Matrix=Serum; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_020,VT_180710_M351_022,VT_180710_M351_024"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	3_Baseline_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_026,VT_180710_M351_028,VT_180710_M351_030"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	4_Baseline_2	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:M	Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_032,VT_180710_M351_034,VT_180710_M351_036"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	5_Baseline_2	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_038,VT_180710_M351_040,VT_180710_M351_042"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	6_Baseline_2	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:M	Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_044,VT_180710_M351_046,VT_180710_M351_048"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	7_Baseline_2	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_050,VT_180710_M351_052,VT_180710_M351_054"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	8_Baseline_2	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_056,VT_180710_M351_058,VT_180710_M351_060"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	8_Visit_2_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=visit_2; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_062,VT_180710_M351_064,VT_180710_M351_066"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	9_Baseline_2	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:M	Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_068,VT_180710_M351_070,VT_180710_M351_072"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	10_Visit_2_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:M	Sample Matrix=Serum; Event Name=visit_2; CF genotype=F508 del /1898+1G>A; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_074,VT_180710_M351_076,VT_180710_M351_078"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	10_Baseline_2	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:M	Sample Matrix=Serum; Event Name=baseline; CF genotype=F508 del /1898+1G>A; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_080,VT_180710_M351_082,VT_180710_M351_084"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	11_Baseline_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=baseline; CF genotype=R74Q/R297Q; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_086,VT_180710_M351_088,VT_180710_M351_090"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	12_Baseline_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=baseline; CF genotype=R74Q/R297Q; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_092,VT_180710_M351_094,VT_180710_M351_096"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	14_Baseline_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_098,VT_180710_M351_100,VT_180710_M351_102"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	15_Baseline_2	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_104,VT_180710_M351_106,VT_180710_M351_108"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	23_Visit_2_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=visit_2; CF genotype=F508del/Unknown; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_110,VT_180710_M351_112,VT_180710_M351_114"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	25_Baseline_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:M	Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_116,VT_180710_M351_118,VT_180710_M351_120"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	26_Baseline_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, CFTR del 2,3"; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_122,VT_180710_M351_124,VT_180710_M351_126"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	27_Baseline_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:M	Sample Matrix=Serum; Event Name=baseline; CF genotype=Delta F 508/Q493X; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_128,VT_180710_M351_130,VT_180710_M351_132"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	28_Baseline_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=baseline; CF genotype=" F508del, 3849 + 10kb C>T"; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_134,VT_180710_M351_136,VT_180710_M351_138"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	29_Baseline_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/F508del; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_140,VT_180710_M351_142,VT_180710_M351_144"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	chearplasma_1c_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:-	Sample Matrix=Serum; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_146,VT_180710_M351_148,VT_180710_M351_150"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	chearplasma_1d_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:-	Sample Matrix=Serum; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_152,VT_180710_M351_154,VT_180710_M351_156"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	30_Baseline_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:M	Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/F508del; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_158,VT_180710_M351_160,VT_180710_M351_162"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	31_Baseline_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:M	Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/F508del; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_164,VT_180710_M351_166,VT_180710_M351_168"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	32_Baseline_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=baseline; CF genotype=R560T/R1158X; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_170,VT_180710_M351_172,VT_180710_M351_174"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	33_Baseline_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:M	Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/F508del; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_176,VT_180710_M351_178,VT_180710_M351_180"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	35_Visit_2_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=visit_2; CF genotype=deltaF508/G542X; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_182,VT_180710_M351_184,VT_180710_M351_186"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	35_Baseline_2	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=baseline; CF genotype=deltaF508/G542X; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_188,VT_180710_M351_190,VT_180710_M351_192"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	36_Baseline_2	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:M	Sample Matrix=Serum; Event Name=baseline; CF genotype=deltaF508 and G55.D  Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_194,VT_180710_M351_196,VT_180710_M351_198"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	37_Baseline_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:M	Sample Matrix=Serum; Event Name=baseline; CF genotype=deltaF508 and G55.D  Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_200,VT_180710_M351_202,VT_180710_M351_204"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	38_Baseline_2	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:M	Sample Matrix=Serum; Event Name=baseline; CF genotype=DeltaF508/ c.2789+5G>A]; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_206,VT_180710_M351_208,VT_180710_M351_210"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	38_Visit_2_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:M	Sample Matrix=Serum; Event Name=visit_2; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_212,VT_180710_M351_214,VT_180710_M351_216"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	42_Baseline_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:M	Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_218,VT_180710_M351_220,VT_180710_M351_222"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	43_Visit_2_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=visit_2; CF genotype=F508del/F508del; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_224,VT_180710_M351_226,VT_180710_M351_228"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	43_Baseline_2	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/F508del; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_230,VT_180710_M351_232,VT_180710_M351_234"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	44_Baseline_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:M	Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/2789+5G->A; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_236,VT_180710_M351_238,VT_180710_M351_240"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	45_Baseline_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:M	Sample Matrix=Serum; Event Name=baseline; CF genotype=621+1G>T/Delta F508; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_242,VT_180710_M351_244,VT_180710_M351_246"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	47_Baseline_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:M	Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_248,VT_180710_M351_250,VT_180710_M351_252"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	49_Baseline_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=baseline; CF genotype=l507del/2622+1G>A; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_254,VT_180710_M351_256,VT_180710_M351_258"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	50_Baseline_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/F508del; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_260,VT_180710_M351_262,VT_180710_M351_264"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	51_Baseline_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_266,VT_180710_M351_268,VT_180710_M351_270"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	52_Baseline_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_272,VT_180710_M351_274,VT_180710_M351_276"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	chearplasma_1e_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:-	Sample Matrix=Serum; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_278,VT_180710_M351_280,VT_180710_M351_282"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	chearplasma_1f_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:-	Sample Matrix=Serum; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_284,VT_180710_M351_286,VT_180710_M351_288"
SUBJECT_SAMPLE_FACTORS           	Quality Control	Q-Std Plasma pool_1b_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:-	Sample Matrix=Plasma; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->1; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Plasma; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180710_M351_290,VT_180710_M351_292,VT_180710_M351_294"
SUBJECT_SAMPLE_FACTORS           	Quality Control	Q-Std Plasma pool_2a_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:-	Sample Matrix=Plasma; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Plasma; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_002,VT_180711_M351_004,VT_180711_M351_006"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	chearplasma_2a_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:-	Sample Matrix=Serum; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_008,VT_180711_M351_010,VT_180711_M351_012"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	chearplasma_2b_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:-	Sample Matrix=Serum; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_014,VT_180711_M351_016,VT_180711_M351_018"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	54_Baseline_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:M	Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/F508del; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_020,VT_180711_M351_022,VT_180711_M351_024"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	55_Baseline_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:M	Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/F508del; Volume (uL)=160; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_026,VT_180711_M351_028,VT_180711_M351_030"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	58_Baseline_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/F508del; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_032,VT_180711_M351_034,VT_180711_M351_036"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	59_Baseline_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/F508del; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_038,VT_180711_M351_040,VT_180711_M351_042"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	60_Baseline_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:M	Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/F508del; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_044,VT_180711_M351_046,VT_180711_M351_048"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	61_Baseline_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/F508del; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_050,VT_180711_M351_052,VT_180711_M351_054"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	63_Baseline_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:M	Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/F508del; Volume (uL)=180; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_056,VT_180711_M351_058,VT_180711_M351_060"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	64_Baseline_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:M	Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/ 2184delA); Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_062,VT_180711_M351_064,VT_180711_M351_066"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	65_Baseline_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=baseline; CF genotype="deltaF508, R 553X"; Volume (uL)=180; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_068,VT_180711_M351_070,VT_180711_M351_072"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	67_Baseline_2	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:M	Sample Matrix=Serum; Event Name=baseline; CF genotype=deltaF508/Y1092X; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_074,VT_180711_M351_076,VT_180711_M351_078"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	67_Visit_2_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:M	Sample Matrix=Serum; Event Name=visit_2; CF genotype=deltaF508/Y1092X; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_080,VT_180711_M351_082,VT_180711_M351_084"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	68_Baseline_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=baseline; CF genotype="Delta F508,  p.S489X "; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_086,VT_180711_M351_088,VT_180711_M351_090"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	69_Baseline_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_092,VT_180711_M351_094,VT_180711_M351_096"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	71_Baseline_2	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=baseline; CF genotype=F4508del/ R117H (5T/9T; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_098,VT_180711_M351_100,VT_180711_M351_102"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	72_Baseline_2	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=baseline; CF genotype=R553X/DeltaF508.; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_104,VT_180711_M351_106,VT_180711_M351_108"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	73_Baseline_2	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=baseline; CF genotype=F508Del/F508Del; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_110,VT_180711_M351_112,VT_180711_M351_114"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	74_Baseline_2	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_116,VT_180711_M351_118,VT_180711_M351_120"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	75_Baseline_2	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:M	Sample Matrix=Serum; Event Name=baseline; CF genotype="F508del, F508del"; Volume (uL)=165; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_122,VT_180711_M351_124,VT_180711_M351_126"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	76_Baseline_2	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:M	Sample Matrix=Serum; Event Name=baseline; CF genotype=deltaF508 and 621+1G>T; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_128,VT_180711_M351_130,VT_180711_M351_132"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	78_Baseline_2	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:M	Sample Matrix=Serum; Event Name=baseline; CF genotype=R1162X/E193X; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_134,VT_180711_M351_136,VT_180711_M351_138"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	chearplasma_2c_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:-	Sample Matrix=Serum; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_140,VT_180711_M351_142,VT_180711_M351_144"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	chearplasma_2d_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:-	Sample Matrix=Serum; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_146,VT_180711_M351_148,VT_180711_M351_150"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	79_Baseline_2	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/R785/S1235R; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_152,VT_180711_M351_154,VT_180711_M351_156"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	80_Baseline_2	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:F	Sample Matrix=Serum; Event Name=baseline; CF genotype=F508del/F508del; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_158,VT_180711_M351_160,VT_180711_M351_162"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	ncH_001_2	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:M	Sample Matrix=Serum; Event Name=nch_001; CF genotype=F508del/3120+1G>A; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_164,VT_180711_M351_166,VT_180711_M351_168"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	NCH_002_2	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:M	Sample Matrix=Serum; Event Name=nch_002; CF genotype="F508del, F508del"; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_170,VT_180711_M351_172,VT_180711_M351_174"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	NCH_003_2	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:M	Sample Matrix=Serum; Event Name=nch_003; CF genotype="F508del, Y1092X"; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_176,VT_180711_M351_178,VT_180711_M351_180"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	hc_7_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:M	Sample Matrix=Serum; Event Name=hc_7; CF genotype=-; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_182,VT_180711_M351_184,VT_180711_M351_186"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	hc_12_2	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:M	Sample Matrix=Serum; Event Name=hc_12; CF genotype=-; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_188,VT_180711_M351_190,VT_180711_M351_192"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	hc_15_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:M	Sample Matrix=Serum; Event Name=hc_15; CF genotype=-; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_194,VT_180711_M351_196,VT_180711_M351_198"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	hc_30_2	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:M	Sample Matrix=Serum; Event Name=hc_30; CF genotype=-; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_200,VT_180711_M351_202,VT_180711_M351_204"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	hc_31_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:M	Sample Matrix=Serum; Event Name=hc_31; CF genotype=-; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_206,VT_180711_M351_208,VT_180711_M351_210"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	hc_32_2	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:M	Sample Matrix=Serum; Event Name=hc_32; CF genotype=-; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_212,VT_180711_M351_214,VT_180711_M351_216"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	hc_48_2	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:F	Sample Matrix=Serum; Event Name=hc_48; CF genotype=-; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_218,VT_180711_M351_220,VT_180711_M351_222"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	hc_60_2	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:F	Sample Matrix=Serum; Event Name=hc_60; CF genotype=-; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_224,VT_180711_M351_226,VT_180711_M351_228"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	hc_62_2	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:M	Sample Matrix=Serum; Event Name=hc_62; CF genotype=-; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_230,VT_180711_M351_232,VT_180711_M351_234"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	hc_64_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:M	Sample Matrix=Serum; Event Name=hc_64; CF genotype=-; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_236,VT_180711_M351_238,VT_180711_M351_240"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	ncf_106_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:M	Sample Matrix=Serum; Event Name=ncf_106; CF genotype=-; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_242,VT_180711_M351_244,VT_180711_M351_246"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	NCF_108_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:F	Sample Matrix=Serum; Event Name=ncf_108; CF genotype=-; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_248,VT_180711_M351_250,VT_180711_M351_252"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	ncf_110_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:F	Sample Matrix=Serum; Event Name=ncf_110; CF genotype=-; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_254,VT_180711_M351_256,VT_180711_M351_258"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	ncf_112_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:F	Sample Matrix=Serum; Event Name=ncf_112; CF genotype=-; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_260,VT_180711_M351_262,VT_180711_M351_264"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	ncf_114_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:F	Sample Matrix=Serum; Event Name=ncf_114; CF genotype=-; Volume (uL)=200; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_266,VT_180711_M351_268,VT_180711_M351_270"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	chearplasma_2e_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:-	Sample Matrix=Serum; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_272,VT_180711_M351_274,VT_180711_M351_276"
SUBJECT_SAMPLE_FACTORS           	Serum Study Sample	chearplasma_2f_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:-	Sample Matrix=Serum; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Serum; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_278,VT_180711_M351_280,VT_180711_M351_282"
SUBJECT_SAMPLE_FACTORS           	Quality Control	Q-Std Plasma pool_2b_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:-	Sample Matrix=Plasma; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Plasma; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_284,VT_180711_M351_286,VT_180711_M351_288"
SUBJECT_SAMPLE_FACTORS           	Quality Control	NIST SRM 1950_2_2	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:-	Sample Matrix=Plasma; Event Name=-; CF genotype=-; Volume (uL)=-; combine="Column_Ionization_type: C18neg; Date Analyzed->10523=Date Analyzed->6853; Batch->1=Batch->2; CHEAR_Project_ID->2018_PF02=CHEAR_Project_ID->2018_PF02; Sample.Matrix->Plasma=Sample.Matrix->Plasma; Raw files->VT_180710_M351_001,VT_180710_M351_003,VT_180710_M351_005"=Raw files->VT_180711_M351_290,VT_180711_M351_292,VT_180711_M351_294"
#COLLECTION
CO:COLLECTION_SUMMARY            	Blood plasma samples were collected from nonfasting participants in the
CO:COLLECTION_SUMMARY            	Aspirin/Folate Polyp Prevention Study [1, 2] at enrollment (baseline) and after
CO:COLLECTION_SUMMARY            	three years of study treatment. Blood samples were collected in tubes containing
CO:COLLECTION_SUMMARY            	EDTA and after centrifugation aliquots of plasma were transferred to 1.8 ml
CO:COLLECTION_SUMMARY            	freezer tubes and stored in a -70C freezer. The samples were shipped on dry ice
CO:COLLECTION_SUMMARY            	from the clinical centers to the Dartmouth biorepository storage facility and
CO:COLLECTION_SUMMARY            	subsequently to the metabolomics analysis lab at Emory University.
CO:SAMPLE_TYPE                   	Serum
CO:STORAGE_CONDITIONS            	Described in summary
#TREATMENT
TR:TREATMENT_SUMMARY             	Samples were received frozen in aliquouts of <250uL. Prior to analysis, samples
TR:TREATMENT_SUMMARY             	were thawed and prepared for HRM analysis using the standard protocols described
TR:TREATMENT_SUMMARY             	in the Sample Preparation section.
#SAMPLEPREP
SP:SAMPLEPREP_SUMMARY            	Samples were prepared for metabolomics analysis using established
SP:SAMPLEPREP_SUMMARY            	methods(Johnson et al. (2010). Analyst; Go et al. (2015). Tox Sci). Prior to
SP:SAMPLEPREP_SUMMARY            	analysis, plasma aliquots were removed from storage at -80 degrees C and thawed
SP:SAMPLEPREP_SUMMARY            	on ice. Each cryotube was then vortexed briefly to ensure homogeneity, and 50
SP:SAMPLEPREP_SUMMARY            	microliters was transferred to a clean microfuge tube. Immediately after, the
SP:SAMPLEPREP_SUMMARY            	plasma was treated with 100 microliters of ice-cold LC-MS grade acetonitrile
SP:SAMPLEPREP_SUMMARY            	(Sigma Aldrich) containing 2.5 microliters of internal standard solution with
SP:SAMPLEPREP_SUMMARY            	eight stable isotopic chemicals selected to cover a range of chemical
SP:SAMPLEPREP_SUMMARY            	properties. Following addition of acetonitrile, urine was equilibrated for 30
SP:SAMPLEPREP_SUMMARY            	min on ice, upon which precipitated proteins were removed by centrifuge (14,000
SP:SAMPLEPREP_SUMMARY            	rpm at 4 degrees C for 10 min). The resulting supernatant (100 microliters) was
SP:SAMPLEPREP_SUMMARY            	removed, added to a low volume autosampler vial and maintained at 4 degrees C
SP:SAMPLEPREP_SUMMARY            	until analysis (<22 h).
SP:SAMPLEPREP_PROTOCOL_ID        	HRM_SP_082016_01
SP:SAMPLEPREP_PROTOCOL_FILENAME  	EmoryUniversity_HRM_sample_preparation_082016_01.pdf
SP:SAMPLEPREP_PROTOCOL_COMMENTS  	Date effective: 30 July 2016
SP:EXTRACTION_METHOD             	2:1 acetonitrile: sample followed by vortexing and centrifugation
#CHROMATOGRAPHY
CH:CHROMATOGRAPHY_SUMMARY        	The C18 column is operated parallel to the HILIC column for simultaneous 
CH:CHROMATOGRAPHY_SUMMARY        	analytical separation and column flushing through the use of a dual head HPLC 
CH:CHROMATOGRAPHY_SUMMARY        	pump equipped with 10-port and 6- port switching valves. During operation of
CH:CHROMATOGRAPHY_SUMMARY        	the "C18 method, the MS is operated in negative ion mode and 10 μL of
CH:CHROMATOGRAPHY_SUMMARY        	sample is" injected onto the C18 column while the HILIC column is flushing
CH:CHROMATOGRAPHY_SUMMARY        	with wash "solution. Flow rate is maintained at 0.4 mL/min until 1.5 min,
CH:CHROMATOGRAPHY_SUMMARY        	increased to 0.5" "mL/min at 2 min and held for 3 min. Solvent A is 100%
CH:CHROMATOGRAPHY_SUMMARY        	LC-MS grade water, solvent" B is 100% LC-MS grade acetonitrile and solvent C
CH:CHROMATOGRAPHY_SUMMARY        	is 10mM ammonium acetate in "LC-MS grade water. Initial mobile phase
CH:CHROMATOGRAPHY_SUMMARY        	conditions are 60% A, 35% B, 5% C hold" "for 0.5 min, with linear gradient to
CH:CHROMATOGRAPHY_SUMMARY        	0% A, 95% B, 5% C at 1.5 min, hold for 3.5" "min, resulting in a total
CH:CHROMATOGRAPHY_SUMMARY        	analytical run time of 5 min. During the flushing" "phase (HILIC analytical
CH:CHROMATOGRAPHY_SUMMARY        	separation), the C18 column is equilibrated with a wash" "solution of 0% A,
CH:CHROMATOGRAPHY_SUMMARY        	95% B, 5% C until 2.5 min, followed by an equilibration" "solution of 60% A,
CH:CHROMATOGRAPHY_SUMMARY        	35% B, 5% C for 2.5 min."
CH:CHROMATOGRAPHY_TYPE           	Reversed phase
CH:COLUMN_NAME                   	Thermo Higgins C18 (50 x 2.1mm, 3um)
CH:COLUMN_NAME                   	size," "Product #TS-0521-C183; Thermo Accucore C18 guard column with holder,
CH:COLUMN_NAME                   	Product" #17126-014005
CH:FLOW_RATE                     	0.4 mL/min for 1.5 min; linear increase to 0.5 mL/min at 2 min held for 3 min
CH:COLUMN_TEMPERATURE            	60C
CH:METHODS_FILENAME              	20160920_negC18120kres5min_ESI_HILICposwash.meth
CH:SOLVENT_A                     	LC-MS grade water
CH:SOLVENT_B                     	LC-MS grade acetonitrile
CH:METHODS_ID                    	10mM ammonium acetate in LC-MS grade water
CH:SAMPLE_INJECTION              	10 uL
CH:ANALYTICAL_TIME               	5 min
CH:SAMPLE_LOOP_SIZE              	15 uL
CH:SAMPLE_SYRINGE_SIZE           	100 uL
CH:CHROMATOGRAPHY_COMMENTS       	Triplicate injections for each chromatography mode
CH:INSTRUMENT_NAME               	Thermo Dionex Ultimate 3000
#ANALYSIS
AN:ANALYSIS_TYPE                 	MS
AN:LABORATORY_NAME               	Clinical Biomarkers Laboratory
AN:OPERATOR_NAME                 	Vilinh Tran
AN:DETECTOR_TYPE                 	Orbitrap
AN:SOFTWARE_VERSION              	Xcalibur 3.0.63
AN:ACQUISITION_DATE              	Jan-15
AN:ANALYSIS_PROTOCOL_FILE        	EmoryUniversity_HRM_QEHF-MassSpec_092017_v1.pdf
AN:DATA_FORMAT                   	Profile
#MS
MS:INSTRUMENT_NAME               	Thermo Q Exactive HF hybrid Orbitrap
MS:INSTRUMENT_NAME               	Thermo Q Exactive HF hybrid Orbitrap
MS:INSTRUMENT_TYPE               	Orbitrap
MS:MS_TYPE                       	ESI
MS:ION_MODE                      	NEGATIVE
MS:MS_COMMENTS                   	None
MS:ACQUISITION_DATE              	Jan-15
MS:CAPILLARY_TEMPERATURE         	250C
MS:COLLISION_GAS                 	N2
MS:DRY_GAS_FLOW                  	45
MS:DRY_GAS_TEMP                  	150C
MS:MASS_ACCURACY                 	< 3ppm
MS:SPRAY_VOLTAGE                 	-4000
MS:ACTIVATION_PARAMETER          	5.00E+05
MS:ACTIVATION_TIME               	118ms
MS:INTERFACE_VOLTAGE             	S-Lens RF level= 55
MS:SCANNING_RANGE                	85-1275
MS:MS_RESULTS_FILE               	ST001079_AN001762_Results.txt	UNITS:Peak Area
#MS_METABOLITE_DATA
MS_METABOLITE_DATA:UNITS         	Peak Area
MS_METABOLITE_DATA_START
Samples	NIST SRM 1950_1_2	Q-Std Plasma pool_1a_2	chearplasma_1a_2	chearplasma_1b_2	3_Baseline_2	4_Baseline_2	5_Baseline_2	6_Baseline_2	7_Baseline_2	8_Baseline_2	8_Visit_2_2	9_Baseline_2	10_Visit_2_2	10_Baseline_2	11_Baseline_2	12_Baseline_2	14_Baseline_2	15_Baseline_2	23_Visit_2_2	25_Baseline_2	26_Baseline_2	27_Baseline_2	28_Baseline_2	29_Baseline_2	chearplasma_1c_2	chearplasma_1d_2	30_Baseline_2	31_Baseline_2	32_Baseline_2	33_Baseline_2	35_Visit_2_2	35_Baseline_2	36_Baseline_2	37_Baseline_2	38_Baseline_2	38_Visit_2_2	42_Baseline_2	43_Visit_2_2	43_Baseline_2	44_Baseline_2	45_Baseline_2	47_Baseline_2	49_Baseline_2	50_Baseline_2	51_Baseline_2	52_Baseline_2	chearplasma_1e_2	chearplasma_1f_2	Q-Std Plasma pool_1b_2	Q-Std Plasma pool_2a_2	chearplasma_2a_2	chearplasma_2b_2	54_Baseline_2	55_Baseline_2	58_Baseline_2	59_Baseline_2	60_Baseline_2	61_Baseline_2	63_Baseline_2	64_Baseline_2	65_Baseline_2	67_Baseline_2	67_Visit_2_2	68_Baseline_2	69_Baseline_2	71_Baseline_2	72_Baseline_2	73_Baseline_2	74_Baseline_2	75_Baseline_2	76_Baseline_2	78_Baseline_2	chearplasma_2c_2	chearplasma_2d_2	79_Baseline_2	80_Baseline_2	ncH_001_2	NCH_002_2	NCH_003_2	hc_7_2	hc_12_2	hc_15_2	hc_30_2	hc_31_2	hc_32_2	hc_48_2	hc_60_2	hc_62_2	hc_64_2	ncf_106_2	NCF_108_2	ncf_110_2	ncf_112_2	ncf_114_2	chearplasma_2e_2	chearplasma_2f_2	Q-Std Plasma pool_2b_2	NIST SRM 1950_2_2
Factors	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:-	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:-	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:-	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:-	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:F	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:M	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:F	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:M	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:F	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:F	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:F	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:M	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:M	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:M	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:F	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:F	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:F	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:F	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:F	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:M	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:F	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:M	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:F	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:F	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:-	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:-	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:M	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:M	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:F	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:M	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:F	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:F	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:M	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:M	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:M	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:M	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:M	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:F	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:F	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:M	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:M	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:M	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:F	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:F	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:F	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:F	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:-	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:-	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:-	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:-	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:-	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:-	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:M	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:M	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:F	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:F	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:M	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:F	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:M	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:M	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:F	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:M	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:M	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:F	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:F	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:F	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:F	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:F	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:F	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:M	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:M	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:M	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:-	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:-	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:F	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:1 | Gender:F	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:M	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:1 | CF? 1=Yes  0=No:1 | Gender:M	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:M	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:M	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:M	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:M	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:M	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:M	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:M	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:F	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:F	INFANT?  1=YES  0=CHILD:1 | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:M	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:M	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:M	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:F	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:F	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:F	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:F	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:-	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:-	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:-	INFANT?  1=YES  0=CHILD:- | Smoke exposure?  1=Yes  0=No:- | CF? 1=Yes  0=No:- | Gender:-
Serine	5203776.3	8367836.1	4473966.6	4207841.3	4363812.8	452348.2	10024444	7451299.5	4191158.3	5532325.6	8468322.8	7749282.9	5567039.6	7431616.1	6843184.3	7854770.7	10310960.1	2448130.7	6544412.5	6083656.2	5680581.5	7162699.6	8048081	7802528.4	3762874.5	3968346.4	8222324.5	9332065.1	7108676.7	7236218.6	6486604	8956129.9	9142928	9711375.3	4630495.5	5345522.1	5766704.5	7822744	5978373.2	5569644.7	6008213.2	6040390	6108863.1	5012859.7	6848359.5	5357444.9	3633749.1	3327387.5	5355080.7	5652875.2	4659314.3	4386714.9	6454886	6424232.5	6694193.2	8082169	8107441.4	8221666.2	7157688.4	5619029.7	6769057	4424825.6	7840754.2	6725580.8	7543858.2	8871634.4	6921681.6	9396540.5	8134511	8634136.3	6450803.4	7108761.7	4045736.7	4404799	10037755.8	6970313.6	4604197.4	5323733.4	5709696.6	6376542.1	7204871.8	5606036.6	5685640.1	5086260.4	6555070.4	8881313.1	8743939.2	6841147.6	4924484.3	1249155.2	1411475.3	936283.7	0	1556387.5	5486263.9	4380955.6	3249458.2	5192665.6
Glyceric acid	32666193.7	24986020.6	30855626.4	26868947	33655816.4	0	63060218.5	42844597.6	22835807.9	0	33369916.6	491224.4	66863995.5	67893474.6	28226562.8	49418003.2	37040335.9	22291364	83079058.7	9292749.5	39626066.7	57028750.1	82808127.7	36819308.1	32159255	31814405.9	112527627.9	48945263.5	91554322.6	51190408.3	31685655.4	0	97795158.2	55934759.4	0	76914781.5	84914835.6	77801895.3	44080745	39775511.1	62309946.1	45340404.1	42552542.6	32923447.7	36980449.8	58411396.1	20906908.4	24870423.8	20311824	28067786.2	12838398	27537585.7	35094537.9	31238648.9	29952481.6	22464060.9	34295781.7	36732471.2	29516930.7	45907350.8	24784953.3	14711440.7	45116511.2	49957362	48953986.9	39700538.1	53198810.4	68962841.4	49680545.5	45004466.4	66108603.9	47672276.5	26675763.1	29819561.2	45501316.9	62159785	168207723.2	242139366.9	210987334.4	29710691	35645289	20054842.7	38010400.1	46945007.8	39555623	37645355.6	41642476.6	21327656.1	23238602.8	18268642.5	21053631.4	17932283.9	15148376.3	18610677.3	25948707.7	25325255.4	24242255.9	27129644.8
Creatinine	4042161.4	10160703	6088129.6	4906824.8	2844930	1438739.1	2680249.5	2345121.5	1244135.3	1406670.1	4879988.7	1608037.9	2517351	2233233.8	3289113.3	3291709.4	2901645.7	1686412.1	2912908.3	3545205.7	2676320.9	2213724	2273843	2710445.2	6094555.1	6000247.5	2955623.3	1883960.2	1869812.7	4293675.4	2031186.1	1487578.1	2431621.4	2104120.1	1477982.6	2688480.3	2578325	2923507.5	1177360.2	2126800.9	2286876.8	2117374.8	3180493.8	3156788.8	2979347.8	1413380.6	6576533.5	6590270.6	6248568.3	5603441.4	5871986.4	6261729.6	3488816.7	1883450.8	5683501.5	6392671.8	2388180.2	2059275.9	2369930.6	2187501.7	1759763.6	1736984.7	2120409.4	1650122.3	3059806.3	3125408.1	2742609.8	1749398.4	1779440.6	2872821.2	2672772.1	2416168.6	5607142.8	6847170.4	1702135.1	1434107.9	2420159.4	2452090	1736243.6	2228177.8	1510181.4	2736525.9	1721385.3	1707782.8	3027727.8	1835497	2870625.8	2003405.6	2343109.2	3040835.2	1668646.8	1656205.1	2103992.4	1702246.7	6488393.4	6253296.3	5638886.3	7410818.2
Mesoxalic acid	292948.2	1631694.5	332560.8	379049.2	281502	1577496.2	300072.5	292981.6	5176239.2	2125435.1	157281.8	5163291	270877.2	279007.2	142701.3	201370.5	141399	185560.6	172052.6	147159.4	164205.5	186862	63593.4	184248.9	183029.8	105153.9	344383.3	237238.4	166875.3	179945.2	164317	3293728.3	143059.7	170200	2982161.4	148093.9	152778.3	186845.8	229831.1	143989.9	172093.8	153377.5	123212.6	150983	148394.8	155995	104294	594822.6	104746.7	114744.7	0	0	186390.4	231938.6	0	923584.1	131204.4	103876.8	1015321.5	5015.8	0	3238435.7	247455.7	0	0	0	192737.8	99130.1	187638.3	2189270	99878.5	142048.8	0	0	0	0	145791.7	0	109310	0	0	174476.7	975400.1	74423.4	24880.5	2851420.9	231326.1	0	50328.5	0	0	0	0	1020502.9	0	0	0	0
4-Hydroxybenzaldehyde	7899825.7	27799801.4	125587837.7	120687759.8	131998121.6	96212195.4	21980263.2	108273670.3	5304613.9	4378971.3	40027179.7	6178976.7	30314623.4	25996261.6	22454568.3	5538865.3	22272973	5169260.2	72586039.3	24870904.7	5922811.2	5971512.1	4962355.5	25268208.5	111758807.6	144933348.8	4121256.4	3452514.2	35118990	4047592.2	13157731.4	15688142.3	31203789.7	39608794.9	5916232.4	23544974.1	10201409.2	25944432.7	23474429.2	5678843.1	6098651	7045221.9	26710020.7	6547661.3	4553558.1	24025915.4	115692921.2	102961337.3	23169802.9	17939376.2	104993387.4	107829614.3	20375148.1	72538237.8	22214476.2	28202614.9	282322.3	0	0	0	869883.7	1191845	23889945.6	0	32721427.6	22151424.6	22311311.8	23638663.2	33628610.3	710233.4	15291047	30881684.7	120745104	133937811.3	22257263.7	54626101.7	2637870.7	0	38748271.7	69616076.9	54029503.9	24762538.2	28970604.8	2616054.9	19861138.5	1029552.6	15547197.8	79430202.2	16830006.2	10870225.5	10388385.2	67695701.9	0	33282578.9	135609177.8	119345000.4	126026450.6	21763266.8
Ureidopropionic acid	1610673.2	706070.7	1266535.4	1183865.8	5631082.6	0	7045014	1138694.3	758901.9	0	1594860.8	0	3841341.1	3316865	6562129.8	8171418.9	7372445.8	329625.9	2778441.4	4587661.1	3194384.2	7591732.6	8294200.8	6763886.5	1141072.3	1924616.4	10547112.1	7060105.1	7501923.2	7492778.1	6854059	553479.9	7419548	7276055.3	306376.9	6664240.8	6842686	8727888.6	5677134.2	5164976.1	6540617.4	5292273.9	3356788.6	5990441.2	5783440.5	8200101.1	2174224.7	2609756	1751321.2	1442884.1	1568574.3	1814702	6774065.3	6729201	7619394	5375703.4	7247492	6694065.5	3879513.6	3226184.4	7416988.9	0	8132392	7022198.2	7132447.1	6065596.1	8444866.5	8542353	6431061.3	5814853	12325636.5	8570552.5	1712735.1	753070.3	6082083.4	5923679.1	3065399.3	4718286.2	2240313.9	3387132.5	2987717.1	1106554.6	1165005.4	2529080.8	4948447.6	8892955.2	6942489	5101025.4	4104990.1	637179.6	909024.3	911568.1	2887405.5	2392615.6	2083607.5	2764817.5	2758016.5	3563671.2
Aspartic acid	0	42844133.6	22934915.7	22079207.5	13217476.4	49165455.2	42558808.9	35076933.8	13918700.3	20307526.9	12112353.8	36959977.9	27805365.1	34690295.6	37912147.8	39625265.8	33702269.3	5204551.2	30718867.6	23021056.1	51136972.1	25304174.3	15830589.1	48580773.2	19596927.4	25119870.7	5927058.9	42333212.3	23825994.4	17486980.3	24413904.3	25811572.7	46985951.3	24884134.6	7773851.5	17901893	24391518.1	30011407.8	42297822.1	30672074.9	30025406.1	17449947.8	18416337.3	25129251.6	25616148.4	17412756	20028835.8	20316441.6	37853582.5	33546312.3	21481599.4	20169294.2	14335333.6	18124696.8	18806571.6	13435673.6	21089089.2	25557833	30405972.6	14834095.1	21378469	12803703.8	24502547.4	36147654.3	16142317.1	39967987	22464452.5	20619942.3	20100705.2	24348622.8	18809214.6	40196381.5	22425404	25865045.4	32117875.1	16391982.9	45337458.3	92775415	52757159.8	16033686.1	12551486.6	11602427.9	17282145	14592117.8	17794566.7	17728249.8	19055615	15952015.6	13714705.8	35780900	39317447.8	44105624.1	30387579.8	27886721.8	17963723.7	23301762.7	21995413.2	33170990.4
Hypoxanthine	6943619.7	113311803.8	41729200.6	48422608.4	126903231.9	8918467.3	414848394.2	341565199.6	201020182.1	203399778	177275426.3	309178186.5	156322850.6	221446904.6	234805119.8	248214258	321921763.5	56874196.4	279048628.7	139005496	423918611.3	250448431.1	248190173.8	271869917.8	17735758.8	24480294.3	239924818.3	154849186.6	315374307.1	164435064.4	210526772.6	443720167.4	416844982.1	224191849.2	197533294.8	286343027.5	311584450.7	280209230.7	457169939.4	223212076.7	238043068.1	211864106.2	155095807.5	161462313.2	137888360.6	248552306.9	43196770.1	33273780.5	125390303.3	125313272.2	62117208.7	62807959.6	157088444.5	98692785.3	184573512.5	148620571.2	276242761.2	318355622.7	142911641.9	347386754.6	171798679.9	219546313.6	368629105.2	546917098.9	288298914.4	373296948.1	302265534.6	398660116.2	269129518.4	254608805.5	317864288.8	397115241.6	67776768.5	69854386.6	415883853.9	297394971.5	126042913.4	251691477.1	204356688.4	212389892.1	236691965.7	170445628.8	216137518.1	209017933.4	286152179.5	235811778.2	259920343.1	197500849.5	165608141.2	43933848	48309797.6	29706410.3	28303289.8	46354586.8	63094100.5	62264600.1	53982285	144701533.2
Phenylacetic acid	1683658.4	2417118.6	6691526	5759868.8	1844895.6	1755763.1	1635982.4	1744065.2	1477307.4	1816617.5	628236.9	1761853.6	1669540.4	1856156.6	2717752.8	1776892.8	2545067.7	1819527.1	1592491.4	3106140.3	1756806.7	1724624	2902846.4	2304779.9	5515214.4	2020706.2	1140392.5	3255978.4	3480458.5	1131742.5	2299060.6	1771827.5	1695152.3	5034192.6	1733184.6	1827950.8	2904484.9	1993047.9	1027278.7	2714760.2	1793998.1	1239951.6	891883.7	2170325.8	3478367.3	1346284.2	5314169.6	5386454.7	1616624.1	1640132.3	3729417.2	4280641.5	2414216.7	2499793.8	1691654.7	1960642.6	2598327.5	2343599.7	2901419.6	733222.2	7395823.7	2068556.5	2035913	1560570.2	3041828.9	1856784.7	1892694.9	1934343.2	1897602.5	1860867.7	1759891.1	1786835.1	4171086.6	4884843.1	1997852	1827625.9	1953739.8	1821493.9	1894584	2157862.3	2071420.1	2000883.1	9921155.2	1354651.9	1836013.1	2553912.3	1827522.4	1932024	1908052.2	1712497.8	2023297.3	1919682.6	1630039.3	1645457.3	4315664.7	4264476.3	3079401	1598380.4
Salicylamide	1162004.8	2147486.9	2244115.7	1977129.2	5321718.4	8661545.4	1504765.8	1535032.6	1275881.4	4225985.9	1215138.3	4451058.2	1305811.9	2556035	1218419.3	3415236.3	1242416.5	2753098.3	1239484.7	1470108.7	1266277.3	1261095.2	1191771.3	1180118.2	1694879	1412811.5	2782482.7	1264848.8	1320094.6	1238945.5	4051695.1	4227635.3	1247971.4	2731447.3	4900896.8	1192840	1163616.8	3399460.1	1146511.2	1201350.2	1145111.9	3261675.6	1126820.6	2238765.5	2369819.2	3359579.5	1399628.4	1433249.2	1350539.2	1487449.7	1602098.3	1534982.5	3139197.4	1005712.1	2793850.5	4461353.1	3246319.8	977403	1135207.9	3422603.2	1170272.2	3630060.2	1242071	4041020.8	1428353.2	1554130.8	862057.4	4693232.8	1193365.2	1085458.9	978843.8	1077747.5	1592626.8	1804136.9	1155175.6	1027997.1	1168117.4	2975793.1	1064117.4	3067038	1358387.1	1251970.1	5189900.2	1270799.1	3164918.4	1053713.8	1153753.3	1043046.6	1095895.3	1003858	3110674.5	3910326.4	3879261.1	2737527.3	1281090.1	1335342.5	1291289.8	1459411.4
Caprylic acid	10287291.4	78989246.3	1973432.5	2360374.1	2135968.2	2377256.3	5967420.6	1590489.4	4010272.9	7486857.7	1875938.2	8769801.4	2131415.7	2862184.9	1823786.8	1890097.9	1427835.8	4975786.7	2109672.3	1120729.2	2249402.7	2092850.5	2402277.9	1057483.7	2590750	1155723.7	2397087.8	2100958.3	1998488.3	1943424.5	1832432.3	3741807.3	32837653.6	3441052.4	1713591.6	4206259.5	2219570.3	6162367	1460651.9	2140803.3	2351262.1	1104436	2090126.2	2091331.2	1615756	1213920.6	956335.7	1030869	24792977.2	27459407.9	529813	0	160573.3	5228359.3	1036496	541908.2	20169338	8102341	1129398.5	0	0	9345792.9	298428	1089804.2	0	457260.9	16798218.5	11676357.9	18284033.6	1622933.5	62054497.5	3543192.4	1065689.4	0	12952955.5	2661685	3447889.9	3154010.2	15181756.7	0	0	769075.1	0	0	0	9298986	804369.9	0	0	147668.1	0	402055.6	92001.1	520235.7	0	532095	0	31569973.7
Oxoglutaric acid	12012796.2	19610657.5	32989472.1	32108952.5	21385981.9	0	18489006.4	12549796.4	0	5082903.5	15630472.6	365095.4	12782003.4	23421016.3	12014897.9	7756998.9	10911731.1	0	14799517.4	10551849.6	7677805.9	19027454	8391687.6	12760488.5	39480945.9	41725517.6	8795506.4	10415218	13086737.1	11420912.3	17463113	537702.4	12360854.2	12228486.9	4900163.1	12837369.5	12803601.5	14913460.1	6688552.5	5473994.6	14006211.1	10348919.1	12318395.7	11409592.6	9786655.8	11541625.9	36717469	35420102.7	33814342.3	29490626.2	29630424	33075322.3	10034294.6	6046025.6	14644218.7	3611243.9	12882317.4	6565116.1	14098121	11552299.7	11852856.9	4644555.2	10497853.4	8988126.1	12671680.3	10125556.8	19794481.5	16040170.3	18062805.5	15129200.1	14377964.1	11932961.8	37167888.7	42538539	9466846.5	10841170	13320867.5	17494711	24858159.3	14051949.9	13377173.4	8865412.5	11430195	9787136.4	9267680.7	8295612.6	14802334.1	9610254.1	10256147.4	1186134.1	1335166.5	1257561.3	845109.1	1039243.5	39703125.2	40952133.2	33978998.8	28888715.6
Glutamine	82453190.9	36178504.3	44962644.3	42313134.3	63182753.4	4386794	130881508.3	89959903.7	32041111.5	6640118.3	88717867.3	7777909.5	86180217	82127743.3	92684331.2	100110226	88398876	5768435.6	68934020	94623154.4	70464544.9	77685174	120669287.2	89000635	45998172.3	50176982.5	104293704.9	87926491.5	86207088.2	87168052	70039096.1	8153019.3	99585747.7	99564833.5	4508343.6	91557367.3	70929614.6	84182021	91895640.1	76571612.9	85998115.5	85920289.9	82400673.3	97519207.5	85813075.1	75233381.6	46524911.6	49810580	41242364.3	26372705.9	38311566.8	34932143.5	87687355.9	77752805.5	105086259.7	96579069.6	112732254	86052529.9	63291953.6	74469733.9	82037229.5	0	73867250.1	95645343.3	85353962.2	101414174.5	104952420.8	115379684.9	94277345.5	113801738.9	68711457.9	80173029.3	40605007	40893916.5	118400446.6	95394363.6	71228116.3	102334784.4	89395377.2	86675526	99814171.5	90228008.2	83790948.3	66840073.1	95112195.2	66419560.5	123742791	91274982.4	77409651.9	33085433.6	32345403.8	25058133.7	25253793.3	28720733.7	38336796.4	39502575.4	40009244	22708819.7
trans-Cinnamic acid	0	2310582	0	0	792405.6	150099.1	1677070.1	1846230.5	0	0	1416161.9	0	1655326.6	1295060.1	1114293.4	1270096.3	1265194.5	156034.2	1764264.1	1714678.6	2306368.5	1353120.9	3155865.8	452120.1	0	0	5347303.3	967526.5	3612022.9	3703891.8	1982051.7	151493.6	0	1591483.1	0	1636962.3	2014808.9	2749339	1755021.2	433046.1	2340796	676713.5	341132	682166	1313897	1957159.4	6442190.9	0	0	0	0	0	947826.9	2591038.3	3160181.1	4160230.5	3100834.2	4154984.6	2158996.2	1702480.9	1585054.6	0	652652.5	0	1634928.7	3493120.7	3378760.9	1433402.8	1189793.3	1669161.3	2859104.5	2053412.5	89290.7	0	2248030.2	1368036.6	0	0	0	1635292.5	2091240.7	2870211	1396718.4	2083997.3	1653776.8	1294325.9	1666860.6	1453453	1132271.5	2334349.7	81950.9	0	10366.8	674649.2	0	0	805852.4	0
Methionine	4714270.2	6817686.2	5000120	4652333.7	1948174.9	0	5321783.8	4957293.5	1597336.7	3777523.3	3555914.2	4827927.2	2575987.1	4076745.3	6503323.4	6921346	7784876.6	2857799.6	4986234.9	6572483.3	2044746.4	3581715.5	10282018.8	4935099	5263354.6	4828858	9404355.8	6178291.4	5158791.9	7044354.4	2851885.6	3751607.8	6694290.6	6880025.3	4053975.8	3393603.8	3590393	9164880.9	4667810.9	2555856.3	3561611.6	3363098	4936136.1	4345559.4	3140100.1	3198885.9	4778903.9	5491263	6299644.4	5669292.8	5160911.6	4695067.2	3413925.8	6945267.6	7375713.6	6710061.5	8622338.1	7734889.1	4549978.5	4211138.6	4279006.4	2653110.4	8403700.2	3185275.1	4729183.9	4891981.7	9006471.5	5920325.5	4129930.9	4314861.7	8286709.7	3924437.5	4969898	4699006.7	7490712.3	5403759.4	2059553.5	5577238.2	3945806.8	2960943.3	3583971.3	6778458.8	2064921.3	3465797.9	3946726.1	6316572.9	6121384.4	2610870.8	1910988.6	3039948	2132374.7	3188085.9	2857307.3	4496447.6	5950169.6	4806046.5	5017119.3	6241233.5
Xanthine	0	2469667.2	0	1026368.3	3753929	6604196.6	7649432.5	7589287.4	1937340.3	1454463.8	4884028.9	4569265.4	6380400.9	8351135.2	4367496.2	6452094.2	2149945.3	2921143.5	4379121	4521604.7	6116340.7	6017458.5	9241543.9	4343534.1	2259824.1	8263697.9	3147146.9	7739516	5350215.9	4714201.7	4417299	6237956.8	9242837.7	5870805.4	6598264.9	5240956.8	4634182.2	4992199.7	4196450.7	3220644.7	4033801.9	7161252.5	4141819.3	5682553.4	3204286.6	5821653.1	5508795.5	0	3073687.5	2775607	8864844.6	3145705.1	3888433.8	5439192.4	5083729.2	4398999	3883397.8	3510381.5	4942058.2	3867083.9	4085180.1	2887597.9	4859588	4718830.2	3853544.3	6676586.5	4449450.5	4900716.6	8159727.8	8796108.9	5376666.4	5406112	15211027.8	6896102.1	5298583	4138980	2680528.5	0	4132609.9	6007419.9	5278666.3	3776241.2	5823175.9	5102719.7	6667972.5	4128903.5	8051560.6	4837399	4457616.8	4589021.6	0	0	0	0	3169360.9	2420987.2	2494116.5	3584957.9
Histidine	31707820.3	37245270	34451477.2	28242354.7	24137165.6	2065339.9	41330898.7	33050758	7874613.2	10260430.3	33581310.6	13068106.8	32857214.1	32789182.5	37162338.5	47494818	35495178.7	7555879.4	24106006.4	30261490.6	22785367.4	34823373.6	53400484	34880347.6	34284526.8	32951652	47953195.8	44325573.3	46775655.1	46995031	30994943.6	11570424.6	38443507.6	41552565.3	11323443.1	35844785.2	36006635.2	50157264.8	40516843.4	29654365.1	39063733.4	31086930.6	32531718.4	49069177.3	35651733.4	40916703.4	32414477.3	20514501.7	32661344	34801967.9	23208505	22655523.8	37116106	36684764.6	54042339.2	39156286.2	37741143.8	44931486.5	28134699	30118889.4	39479547.8	12558928.4	60177112	38949036.9	31923257.2	42743494.8	50413705.5	44960831.9	29859049.5	38126934.8	36384139.5	37120558.5	22100391.1	23972812.9	45534995.2	32039945.9	24846813.9	25142596.9	25303650.6	26647257.9	36653357.1	31956947.1	29331175.2	32993257.7	28901871	36103887.3	37351964.1	26802125.3	29451389.7	11432354.2	8537785.5	11936396.3	9411671.2	8748087.9	19723650	19277966.3	17126873.4	30572809.1
Pelargonic acid	2245210.7	26209617.5	3470830.3	2146893.1	2788734.5	3242756.5	2427554.3	2706865.2	3480818	2406277.2	1900173.1	3853966.5	1527812.3	4619353.6	3358545.2	1892613.2	1608113.1	2103508.2	1803577.4	2179970	4897191.9	2372565.1	2051946	4082315.7	1163404	1242172.4	1700470.6	3380983.2	2568644.4	1275416.1	1564426.6	11456130.5	6429501	2358633.9	5348048.1	3444846.5	3130203.6	4543572.5	3318604.2	3081463.4	2196712.4	3377509	2688388.3	2015224.7	2689792.6	2509915.6	1112056.6	1439664.4	1447889	1422173.5	806455.4	507958.6	1933543.1	2629921.5	1297719.3	2301021.5	4401675.4	6350804.2	21110053.5	1744468.9	4852621.6	6266548.3	3847617.8	8097892.4	2729711.2	8544889.9	3294781.6	1551688.8	3175692.3	1490683.8	2206006	3879212.6	1049283.5	1812299.1	5743426.1	844469.1	998280.2	1318737.5	1227730.5	2970901.2	1755213	1754980.6	1748942.1	2381065.1	3229336	3374322.8	2972827.5	3389302.4	2813011.6	1333998.8	2010215.7	1195809.9	1176867.3	1187027.2	919429.5	967190.3	1178480.8	1600833.4
Indoleacetaldehyde	1156384.8	1779453.3	538286.1	592922.1	954414	747927.9	995463.6	746043	665811.8	1011403.9	816132.4	462777.1	771847.3	636612.3	1023060.5	1129571.7	1094674.9	926838.4	535083.2	732033.7	168167.2	910447.2	339990.5	695823.3	548435.7	478333.9	1459169.5	1654859.4	1068659.2	978802.4	872561.1	1013314.6	941944.3	1064174.2	915143.6	849477.3	906522.3	1517999.3	1003039	931882.3	1375017.9	994836.1	1018734.1	729671.4	1000459.1	1024073.8	603545.2	589858.7	691402.5	666583	545323.4	612746.5	978899.2	889784.2	997069.8	347855.7	1055357.9	986176	1017584.2	950748	1461108.7	630672.9	1080117.3	1194888.3	360895.6	1102752.3	1686521.7	378792.8	1090594.6	1082249.7	1251338.4	874450.5	775147.1	819138.7	1536641.6	285222.4	644329.8	865415.8	917033.2	1149839.6	1402521.6	1040714.1	1090015.9	1113369.1	1083238.5	1164167.2	1876486.6	1073265.1	1033543	823332.5	721607.8	730236	729324.7	841271.6	551081.1	577131.7	687015.4	768576.6
Aminoadipic acid	641397.2	1877035.4	601165.2	495366.8	592053.2	411625.1	1212433.3	862087.2	2014354.8	1143708.9	870749.4	1800882.7	1419228.2	999824.1	851394.4	820883.7	1200406.9	316664.6	518237.7	801573	1097129.7	1090325	1051690.4	1134105	708891	753235.9	825832.9	967329.5	868377.8	892052.9	1234794.7	1599625.2	1914864.8	911766.8	1109539.4	1126978	921229.9	1255532.1	905404.1	1075253.6	2498154.4	1135478.6	974804.3	1336789.2	1528277.7	640585.2	775288.2	844140.1	943581.3	958463.7	744917.1	709991.9	878102.3	666695.4	1226123.7	1005287.2	1032712.2	910061.9	867704.8	946540.5	1253336.7	977476.8	1335294.7	1059801.7	763498	1149394.5	2301110.4	1777637	1100585.3	1286274.4	1756450.1	1044229.8	787447.6	1120026.2	1235593.9	1084610.5	2352013.1	1561122.1	2152097.9	1039203.9	1175093.8	1537298.7	1347851.2	1182487.9	1077928	1057274	1180714.3	726198.1	1197506.7	449640.3	325145.4	354187.4	324903	284652.3	1116241	904956.7	744396.3	1118857.3
Phenylalanine	30880708	63821888.9	28815124	29350263.6	26852512.6	5751196.4	47815505.3	39717693.4	27437719.1	12315668.1	34089832.2	27873267.1	33608382.1	40995701.7	68850537.7	63715385	54484480.4	19002911.8	56778728.1	27610209.9	54531805.7	53461465.4	60548797.6	41632152	30641541.5	32911768.6	71025854.1	67969927.6	62107296.5	56428521.4	37777698.8	23706858.8	54338388	40374218.8	14224853.9	35000063.6	47052227.8	70981863.1	52031668.2	44554305	38526555.3	28752142.6	38372804.7	43881808.3	40400165.1	39614620.9	32169812.8	31331514.3	43857134.7	44749033.6	29641487.1	31117041.5	51064031.5	56248096.7	65110365.7	77227812.2	65374694.1	48666364.3	53503040	30252718.6	43878362.8	27532775.6	75883228.5	46229402.5	40624507.7	35031602.2	52401230.4	44612150.6	33016679.7	30808809.9	66263801.5	65518445.6	31087005.6	34402414.1	63157578.1	39905241.1	24883401.5	38338353.2	29241698.5	35180231.3	27597962.9	32826508.6	31136944.3	27702274	33078750.4	52243914.8	39495336	20797621.6	29998918.5	21398526.6	20465218	20425195.1	17344053.2	18377668.6	33356123.5	30520575.4	33105633.4	52782947.7
3-(2-Hydroxyphenyl)propanoic acid	7720249.2	8113116.3	5570844	6356107.8	9584227.1	2528908.4	15674207.1	72815034.8	4474743.5	4829236	30137407	13359816.8	15260231	9934773.7	16840435.8	18283334	21839610.7	9065130.4	27401089.1	32190775.2	28718319.1	24153083.8	23069695.3	16097215.5	6741452.2	7474973.7	15127014.9	16134382.7	25644999	25165181	9446330.6	11584150	22455888.5	20464056.8	17602580.6	15334127.2	21397458	22806141.3	12550788	31927214.1	16709768.3	19008453.8	12506505.3	11913044.3	11037310.2	16443646.6	4772862.4	4838789.1	11178174.4	9027493.6	7906240.1	8014000.4	16176707.2	16700761.6	16714482.6	25131413.3	33479697.9	16307262.8	22519690	16244856.1	27913755.8	13292254.1	18408480.7	17026457	34683141.3	15721528.9	23373153.8	8960390.1	31791085.9	20985115.8	11853580	15243059	7843940.1	8777482.4	77785777	8852532.8	6250224.2	5500628.9	6430986.3	23771270	33864285.4	16617859.5	14324795.2	23874403.2	23487067.1	18134790.9	22511410.7	19095663.2	12532831.4	6419207.4	5936696.5	5115156.4	4448540.8	6575062.8	6650489.6	7817370	5246461.3	11435521.1
Uric acid	311963113.2	315902258.1	276475848.9	284885745.9	281131815	101920543	205508729	238227669.3	119351373.8	138176359.7	336563569.9	260047119.7	392915174.4	539319403.5	306407131.2	398592958.9	427203964.5	68132402	233415311.3	438070129.4	302757671	425697261.8	265318733	460808737.8	296478441.2	308782514	264582756.7	238528763.8	400743671.7	388478243.8	466358589.8	151929611.7	350075664.3	419603778.7	143325654.9	286699744.6	431096735.3	267858800.8	379145587.6	338928501.8	386651872.3	329590954.8	291470864.5	368975061.5	383024959.4	382788967	320702054.4	304598984.1	337889643.9	326029470.6	305931277	305161655	446019884	530837089.4	416218077.6	289013804.7	232338489.3	133587076.7	189881512.4	444683027.3	297015887.3	138123303.7	324293216	449752651.6	277859795	384587310.3	393033215.9	283474077.8	266136505.6	383712884.6	266438336.9	310775358.4	326959741.4	359897090.7	299113457.7	260972136.9	326128753.7	305537152	295455771.4	452749907.3	335572068.1	280953466.4	375791067.4	509611799.3	413863232	424168372.3	310691890.1	284944495.4	334987126.5	208003330.5	129142447.2	190052783.8	65629542.5	103893082.1	339538680.6	333714138.1	307658452.4	335798052.6
N-Acetylasparagine	116492.9	559376.3	953666.4	232003.4	102170.1	0	109330.5	0	159062.9	202030.1	0	192897.3	144847.7	137706.4	105754.9	128746.4	0	51702	819937.1	1350343.1	0	183400.2	575689.6	0	217505.8	142591.8	118766.8	1024199.2	0	129456.4	46194.1	125870.6	409060.1	152568.8	117769.8	93956.2	2033526	90726.3	186578.6	0	176141.1	121428.7	0	158870	145440.9	1294787.9	355462.5	431280.4	508149.9	306693.1	161754	207387.6	0	95730.2	169418	286413.4	0	0	0	0	253932.2	125019.9	226843.7	123938.6	187897.1	142543.9	219821.6	256706.4	128034.8	227149	111284.8	0	277698.4	195994.2	252834.7	0	1214933.8	2553645.1	1253874.5	194764.2	552034.2	265476.2	230627.3	322781.6	110350.3	308281.8	136673.5	272563.9	0	413010.5	499710.7	362746.8	97232.8	145203.6	278742.5	720664.2	261093.3	225146.9
Suberic acid	0	2493280	1411678.6	931004.2	1609508.8	60418247.2	8325725.8	10677825	4538264.8	4771419.2	4106304.8	10297419.8	3733155.5	13765300.9	13910411.6	6597556.7	7006182.2	826390.9	464387.1	9431160.4	10176383.4	4526392.7	1052693.4	11822498.7	692555.6	1006053.1	1040842.3	4745014.3	5320595.5	1209971.1	11555736.2	19697191.2	17410077.6	5262549.9	2875280.5	7134095.8	4858045	15120140.2	6426418.7	5374149.4	3567644.2	5697266.5	3707226.2	1429440.4	4676008.3	5651795.3	403363.6	581497.7	265719.1	2734953.4	3066488.3	3415597.1	3010890.9	3656338.7	4913157.1	3605189.6	4646478.4	6675687.8	68914140.1	4701207.1	5787354.4	3492085	4484843.9	5995431.2	3017140.6	14948219.6	3769336.7	3748511.1	4511497	6312648.6	7179779.4	15502739.7	1793002.7	1764696.5	7041210	3734742.8	2847069.8	3367636.8	3295149	7307060.7	4040883.3	3957933.6	4048847.4	3750416.2	6479918.8	5906105.8	5474578	8168605.8	3559340	2666880.6	2863826.8	2331322.4	2702600.8	2768085.9	1986079.4	1724100.1	3634487.8	3007666
N-Acetyl-L-aspartic acid	732321.7	10618438.6	10418609.9	6085852.8	602572.6	0	1116491.5	797578.7	4872864.4	5935729.6	501914.2	2600402.8	490498.7	838498.2	1027996	0	1681397.3	355883.9	465390.9	470800.6	452472.9	562232.4	488583.6	899232.2	8928797.3	11752140.4	617397.1	495675.5	442603	396080.3	4425110	2082769	1060283.9	489378	882588.7	358979	3392169.9	1531699.1	479399.5	0	378558.1	437402.5	0	503182.6	352957.4	307742.3	8260098.7	11183209.7	10561703.3	9828241.6	4675455.7	4682898.3	466490	279262.7	578713.9	454887.5	317027.6	667505.4	350918.7	344257.1	517170.8	618328	672732.6	542321.2	434812.2	620960.7	867124	1541673.7	851174.1	661990.3	523136.4	790653	6964854.2	8602615	736599.3	503389.5	13297186.1	15565307	15519465.9	686848.6	639699.2	796893	450434.5	673765.8	539949.1	412730.1	520663	417597	369391.4	3980647.9	6541907.8	4807882.3	2776065.6	4843977.7	7508076.2	7715843.4	6561131	7989070.1
Indoleacetic acid	8216775.2	10653006.2	6677949.5	7131840.7	3760271.7	22514836.7	5282191.2	7107205	2044016.2	4115893.1	5816553.8	3560446	18429034.8	3828843.3	11457771	9615409.6	13568458.4	1487644.7	13981983.2	11468911.9	4746536	9344441.5	11674620	6230736.7	6697511.2	8918118.2	9781326.6	8770163.2	7611258.8	12699984.9	8388246.5	4550473.7	10778794.5	4846374.2	2979732.7	5873553.7	12379817.7	10956361.2	7765051.5	25110396.6	10711048.4	61963325.4	34226682.6	8700812.7	13428036	31488807.6	5643512.3	5942428.7	7544017.8	7508500.1	5469132.8	5844360.1	4408378.6	15350371.3	15453785	12615912.3	11668671.3	6788255.9	10832983.9	16853539.4	59984454	2094241.8	23473024.5	10264960.6	23121991.7	8146561.9	20728580.6	11794468.6	7501184.7	11825394	6503749.8	7339562.4	6451673.7	6827499.4	36188530.4	9367945.4	14051813.2	4036738.5	7732005.2	6925427.9	12119119	10706724.1	7357316.8	12660090.5	8635726.9	6169317.1	4698896.2	5809178	8110139.6	3904457.6	1376293.5	1612047.6	1330414.6	2325080.4	6141786.8	6156271.3	6136769.5	9357467.1
Citrulline	5250945.4	1339658.8	3602526.1	2198936.2	4356453.2	5088095.9	2598931.9	4428937.1	2957816.4	1803112.5	1881238	2891775.1	7228682.3	6975444.1	3773678	5777757.1	7384914.9	1177438.7	1970752.9	5069816.5	5945861.9	6064817.6	2597753.8	5720653.4	2652191.7	3381785.4	6016655.4	3520286.4	7993363.7	7869446.2	2491461.2	4029394.7	2911957	5163801.2	2312536.1	4773430.3	2951168	3214324	6785976.4	709435.7	5446497.7	6772811.6	2889501.4	6827936.6	7361793.6	5942072.4	2577390.4	3285321.3	1427536.6	2218440	2946285.2	2713240.6	7690713	6783568.1	6301558.2	4677996.4	7267212.4	4492185	7114551.4	1828855.3	8721163.9	3371931.1	7454355.2	5761022.3	6386380.3	4150377.5	7051464.6	3695203.7	3220990.3	4716847.5	2869334	1507617.4	4281496.6	2974322.3	3823942.6	7467056.9	1892356.8	3675206.1	3879691.1	3032532.8	3288355.4	3628626.8	2701567.1	1571757.2	2714180.9	2716477.4	2728269.9	3181075.8	6980791.4	1852813.2	1421276.6	2001847	2525061.9	2112041.7	4254783.5	3516173	4201827.9	2664349.4
Hippuric acid	35082698.1	60533288.1	35982489.7	36086519.6	18914228.6	6206893.6	8734230.4	8127842.7	10564038.7	15146961.6	46635261.6	12447408.1	77007745.4	15990473.4	26105081.2	23189306.6	40883251.4	15351598.2	45059401.1	11007310.3	8653938.5	68108981.2	106686057	12714134.6	36963926.2	41404104.6	16488471.1	16110254.8	26700731.1	23600656.5	59506996.5	11292736	22046483.9	9947672.9	18172231.9	7066773.6	17268910.9	30493970.8	13253834.8	77632093.5	9125496.3	418826584.1	62834359.9	12873899.3	8447180	11093417.4	39853209.8	37610091	99597261.1	124330920.8	47621265.2	48161206.7	3257808.5	12981341.6	18028415.8	19697145.5	4851565	136067817.4	0	40911049.5	20110654.2	12132680.9	22301159.5	12836610.2	53210079.4	0	18433918.8	6055202.9	5978752.7	7999641	63417895.6	54158637.4	52627231.2	58493173.7	19059445.2	0	0	36524792	18014558.9	0	20557458	254571265.5	48194911	0	148926466.2	0	0	7857242	2012213.6	7028839.2	0	51788284.4	0	17504125.6	47482389	52555454	37834902.3	171339027
Tyrosine	21427853	38923140.2	23880178.8	25386074.6	22940581.1	7598763.4	31068643.7	13157631.1	18310088.1	16836709	12156856.4	36160640.8	21132367	16932329	39180135	47349761.1	38830631.5	17279132	10647195.1	27551169.6	37212663.4	29347541	86624180.8	26264567.1	24582952.3	25647631.8	53758289.4	39707433	28711940.7	39910372.1	16438790.8	12790287.7	37296357.1	21704542.3	15148530	15031692.6	25275253.5	38330652.6	20172007.1	21333796.8	27060422.8	18993673.3	20722311.7	25800986.7	27015780.8	18228122.7	23609096	25185594.3	30103921.3	29904096.5	24159484.6	23467546.7	35692250.3	45448083	43790082.7	42598392	49512981.8	29233461.6	31801911.1	19469840.3	32868597.8	17733039.3	43351763.7	22139743.9	44192736.4	16889801.6	33371036.8	36917960	21278189.8	23833757.2	44744155.1	18193825.3	22064720.1	26235239.3	43654097	36096886.7	11454734.6	32466147.3	26335037	15206438	24278241.2	20694110.3	17732394.5	13588658.9	22446090	46911737.2	37116802.2	8892160.9	14160237.9	8505592.5	7840680	6440248.2	1894728.3	8639221.8	24943436	23044913.4	22790477	36208449.8
N-Acetylglutamic acid	2265661.7	4831889.4	4431207.6	3823427.9	545141.3	0	339512.7	0	649704.1	946701.8	757861.7	861308.7	0	2499797.2	2586211.3	0	0	0	363254.8	441142	327221.4	3944881.3	12501019.6	0	0	0	8953115	392455.8	316476.5	0	450075.2	704067.7	5063258.8	406348.5	396350.1	456208.6	329437.6	400881.9	301031.5	1826836.5	493852.1	6274460	3397692.5	3680615.9	494029.9	1701860.9	0	0	0	4761714.2	4586371.3	4470987.9	2781168.1	0	5191111.1	0	1342777.3	7783087.1	0	0	2492874.7	167439.8	375546.1	101730.4	322086.9	478640.1	4811178.8	418478	598741	432274.2	9722945	0	4585610.9	1681758.2	0	0	0	425420	544705.6	159823.6	511497.1	285798.7	147449	0	2116817.2	0	385836.6	259644.7	107116.9	60395.5	80203.1	0	97556.6	21226.4	5026291	0	182572.6	5150674.3
5-Hydroxyindoleacetic acid	0	0	0	0	0	345259.5	0	0	6567647.3	2031242.8	0	0	0	0	0	0	0	2296118.1	0	0	0	0	0	0	0	0	0	0	0	0	1526625	0	0	0	0	0	0	0	0	1639007.6	1728197.4	0	0	1539809	0	2058025	0	0	0	0	0	0	0	1348811.3	1536865.1	0	0	0	0	0	0	4167749.9	1762437.8	0	726209.9	2366382.6	4441154.1	0	3616285.2	1901653.7	2873277.6	2427636.6	0	0	1460910.2	1359072.6	0	0	5313627.4	0	1130927	1283939.4	908676.9	950724.6	3262465.7	1371502.7	1245977.7	0	977529.9	0	0	0	0	0	0	0	0	6131019.9
Quinic acid	2403535.2	2573671	637136.8	447011.4	6108461.6	661021.9	664752.9	415551.1	702277.4	424514.7	9559395.5	445894.7	517926.2	584310.8	422998	326193.8	359654.5	494409	404905.3	492275.4	419859	602846.4	458832.7	580497.1	561493	1948457.8	386474.3	783891.3	4885160.8	3356677.1	3177876.9	703518.5	540861	505144.1	369550.5	411974.9	935491.6	2843131.4	370872.4	4051068.9	3254002.5	386380.2	411916	476080.6	388779.8	663062.3	563020.2	892520.7	1394267.7	1500012.2	813255.2	873124.7	517180	636393.8	6912014.4	630066.6	532292.7	600352.6	620122.3	629608.3	583036	612644	808244.8	589069.2	6861537.4	493524.6	590805.1	523862.6	509322.8	947147.7	603369.2	482306	1188745.8	1334189.1	663234.4	521930.4	615932.2	559815.7	650922.9	550029.5	597574.7	605940.1	666723.2	479593.9	749843.8	497898.3	527581.6	693192.5	716117.9	8883700.5	707303.6	512978.2	580561.6	491935.1	1755768	1950666.5	1682818.8	2671462.5
12-Hydroxydodecanoic acid	3569811.7	5187725.5	5449893	5731851.6	5297540.9	4604951.8	20572746	29088771.9	9193504.3	5073012.2	9331238.1	9371449.2	12133251.8	25202123.1	17982810.6	9887991.8	12525795.8	5561373.1	6639568.6	22349138.4	18239202.2	7262938.4	10236185.3	18334544.2	4033669.7	3720843.1	6151158.9	5705902.1	6989215.1	3415507.3	7166279.5	16490081.4	20745948.2	10150958.9	19279574	20130229.6	8783368	12312222.2	17958587.5	9349284.8	4678327.2	12483256.5	9198788.7	23880398.5	14659654.1	5879300.6	3569619.2	3419651.8	3894740.9	5301818.4	5104875.3	5594723.7	10613570.8	8938510.4	10843565.3	6283879.2	47630566.6	11408767.9	24575678.8	5622808.7	12146571.4	8108599.7	11460191	20174872.7	5474844.6	25161567.8	12953932	11593904.1	12149321.8	22038726	6453235.5	14243729.6	5238277.8	5682588.7	15201803.1	5220974.2	7329210.9	3995194.6	14872554.5	19035128.4	15470147.5	9262705.6	11145689.6	14635146	14237024.5	14185758.9	13332997.8	12765254.8	14204802.8	6169436.4	11253987.3	2247371.3	5212150.1	4573579.4	5288855	5239717.7	5020536.1	6153239.1
Pantothenic acid	0	0	0	0	0	1217106.2	0	295067.4	0	306273.7	0	1898479.3	267480.6	211494.5	0	0	0	573375.8	467753.1	0	0	0	227325.3	0	0	0	1320289.2	0	0	502087.9	0	1025233.1	3088483.4	0	1162196.3	0	0	0	0	0	0	0	0	2038878.9	0	0	0	0	0	0	0	0	0	0	396774.4	529403.5	780463.6	664635.2	0	615054.2	0	548264.2	0	0	0	0	1746845.9	702354.8	5633924.9	227510.1	727351.6	1131761.4	0	1015773.4	0	0	1126497.4	0	0	0	0	0	506713.6	520159.2	373665.6	329810.7	335627	827217.6	0	0	0	0	0	0	0	0	0	0
Myristic acid	231211685.1	157240526.3	256693418	245924637.2	61095917.4	111893633.2	316989832.7	604943090.7	147689861.5	150464675.1	337281437.8	198018945.9	946202899.6	1019552966	155426408.4	165999137	201979317	159213578.1	92994966.2	772683979	209549918	72143381.4	441341461.7	364045660.6	236312754.7	251481062	53513738.6	121490717.6	87318885	157884852.9	59120663.7	210960872.6	148786545.1	353986999.5	515703906.3	418890733.7	63502846	716220249.5	430124014.7	108797421.1	88201446.6	127939961.5	57481444.6	698695559.4	417660550.2	47153183.2	232753024	224842488.1	89530614.1	51344130.8	181270607	193738589.3	485615227.9	93309059	672285539.7	152490378.3	56754295.5	29371609.2	262160054.8	2784767.9	192507221.4	270572817.9	163953317	622748245.8	74341534.3	551654081.6	317816794.9	470859026.2	71567275.1	489912035	22442906.4	97139184.7	185143300.4	211344262.6	250087320.2	125082518.6	205021234.8	50570683.3	385213601.3	1051023372	687297816.2	155813842.7	450594353	562102729.6	487162873.5	181001267.8	240379838.2	355672366.2	725886456	148550011	549567935.1	23525684.1	201144703.7	196531723.7	191786853.1	178922532.2	187153967.2	63212730.1
Ribose 5-phosphate	101168.4	220563.3	1568930.7	90721.3	0	230250	0	0	985439.4	129817.4	0	237949.2	0	0	0	0	0	0	218271.1	0	822013.1	0	0	175412.4	120282.4	117930.3	0	0	0	0	0	205498.9	338400.1	0	197406.4	0	0	133697.6	89433	0	0	0	0	0	0	0	0	0	326382.7	0	134335.4	0	0	0	0	0	121024.7	0	0	0	0	0	0	0	0	0	0	0	113964.7	0	0	0	165740.2	178531.9	197845.5	1854842.8	750562.9	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	225091.4	0	262421.1
Cystine	4278613.4	1517205.7	0	1271567.4	3782841.5	0	4449427.4	6338076.6	7074132.5	13353199.6	3154322	20733865.6	12251808.1	14712473	7035349	6689696.9	5641199.5	9720115.2	5213840.6	9261300.6	6669542.1	3971784.6	4875161.7	9232473.2	6084738.9	945871.9	4161563.8	3893317.9	6908517.6	8124712.3	4163547.5	15122226.2	8108069.5	5993024.9	18504986.6	6802015.5	3865157.8	3238695.7	8574507.7	3612778.6	5245848.1	3392590.5	7428994.2	9076917.5	11620021.2	4011385	1455665	3041836.8	1243588.6	2721662.2	6875338.2	7354613.2	8021348.3	5716209.8	9484007.5	4788448.8	7203803.4	4535405	3562520.3	5038973.4	6414162.6	10920379.2	5179641.1	7959138.2	5281652.7	7328782.5	7141773.8	8906514	5242689.2	5663897.4	8484841.7	5413311.8	2624501.5	2752481.4	5971300.7	4424142.2	12132003.2	2490149.8	4064332.6	21899146.8	11904701.6	5648780.5	17551909.8	12854004.1	9708886.5	4003660.7	4878189.2	4887581.3	23204016.2	4031067.9	3390653.1	4094461.1	2618077.8	2498890.4	3234126.2	2158888.1	2022116.5	2229503.3
Uridine	5278420.3	6068084.3	3059320.6	3936578.7	4587740.7	3863889.6	12723000.5	7954315.6	2426159.5	3842409.9	8904608.6	3796763.1	8439751.6	6844171.5	5623048.5	4710441.5	4867500.2	2089266.6	4169776.1	4967709.1	5035555.5	6098561.7	4898791.2	4299483.5	4131544.4	3178883	0	4297569.5	4531206.7	5951271.9	8514302.2	5011277.8	10198120.4	4046271.8	5210781.4	6541984.7	4950332	5690879.3	6429155.5	6189486	4253292	4288020.5	6135648.4	6079171.3	5507118.9	8388208.6	4471619.1	4772616.1	3887141.6	3807905.9	3579509.6	4246081.9	3868352	3778134.5	6855161.4	3963653.4	4769221.5	3704003.3	5059902.3	6339980.4	4899918.1	4232729.9	6873293.5	7196355.3	4173404.5	7904885.3	8108307.9	7217494.3	6549608.6	5982531.4	5726979.5	5987021.5	3598042.8	4516246.9	11691273.8	4961528.8	6745144.9	5996776.4	6434743.1	5932476.3	6584289.6	10771388.3	7357233.6	10760037.2	7830393.4	8405559.6	6146411	6654819.1	5214479.6	4188275.6	3617068.1	4353938.6	2220852.4	2869048.4	4592665.4	3327289.4	3430391.7	3238195.4
Palmitoleic acid	834624194.2	347268359.5	736622049.3	688572536.8	131790952.5	363470379.6	464803060	866801594.8	102605846.3	95964033.1	449852273	125022355.4	2681993147	1424346239	135226093	122120109.6	379922844	154293226.6	410434431	3000543804	541836523.5	159045649.5	426862425.4	980694288.6	724994544	768618594.4	84218761.5	147562375.2	144011392.5	226055783.9	97737233.9	261221816.5	101309795.8	94689551	561447517	125290744.6	116147443.6	417429952.3	1212169773	167640155.4	101266750	319553265.7	87573779.6	1721303633	924733194	72240686.4	748498649.7	669282508.5	265330416.2	204735706.3	650425891.1	688101937.8	475084609	51022054.8	1033170088	198887132.1	18678624.1	17200080.4	567874561.9	0	666279817.7	134173533	226441265.3	1851744458	96931119.2	468149279.9	42698520.2	158180158.3	76570774	628490856.7	21644401.5	38887260.9	651705029.6	768555269.2	28457072.3	36262395.9	742363948.7	4931948.3	206444695.2	2367705869	1345009900	206019194.4	407618996.3	1421350734	464746599.6	9604493.6	291669649.4	915928457.1	2609026605	478215812.4	1658878939	131759653	623385236.2	219998908.4	672580113.6	604568047.1	635788286.4	234461573.2
Palmitic acid	2643797763	1893645785	3050829222	3005814599	615685968.9	862056340.2	1685530235	3372391293	1368406323	1145997025	1732976135	1695526483	5541696510	4492084777	1245494310	917325163.7	2778616863	1512949407	957381861.2	4816991358	2027914834	1019301531	2671657436	2745683800	2826944939	3076289936	494270052.7	831139463.1	741827161.4	1177455556	821481290.7	2749666137	939622309.3	1646587559	3508037579	1423265467	644317378	2317909517	3496702896	878157214.7	535936313.7	1210995609	533068699.8	4995588136	3142553073	425606436	2613687220	2573958262	1066691564	1308869152	2518099303	2532688056	2755243127	506693302.3	2944189913	1145452620	418796635.6	480119558.6	2348370380	270869749.9	1467049758	2247691644	2016745902	4848494279	718411664.5	2322145029	1153088760	1378844299	896918628.6	3305687361	575669238.5	747302240.5	2501666368	2812490696	970680310.3	1369147990	2374018247	783536189.3	1344197601	4637110309	3421036046	1305334160	2354938339	3898278133	2174756863	689566870.4	1093843082	2644050254	6406251699	1953189546	4184306014	886490424.1	2395893222	1168849520	2619547444	2336048504	2338226141	1259756726
Heptadecanoic acid	61816361.3	34837237	69239662.5	65665907	15527108.1	13594001.1	19598051.3	79559899.8	21366509.3	15776412.2	29462920.2	22315233	179908329	131522920.3	37745819.1	27773351.6	101610719.2	17728705.5	13688701.6	113046795.8	41438635.2	17728426.4	92450527.8	80908817.3	65731480.6	71142383.5	13008970.2	26872079.1	19746323.1	42046165.3	11745199.7	27398537.4	16636094	17722308.4	64162223.7	19466075.7	14329703	116938948.6	79541717.1	34711508	8242419.1	28289812.8	13209827.3	161973365.3	72806206.3	13318009.9	62413892.4	58673403.3	22603445.2	24778293.9	61138483.4	58213940.3	99605663.3	15491073.3	116902306.5	59188085.1	9323029.4	12637809.4	57922891.1	8736771.3	42481199.4	23173856.7	57843952.5	111233764.7	30117293.6	85446579.7	15083405	16723088.3	27572337.8	60209698.7	14267669.9	10116913.7	60007317.6	69892487.5	11892895.2	10552892	21141551.8	7887884.7	12931002.9	67903246.2	90537979.2	12644549.7	38681349.3	42598214.1	26330694.7	10268681.5	25236192	91235809.1	220611014.1	59215957	120895741.4	15748456.6	51692953.6	26660761.2	61474800.3	57580714.4	58473289.4	28032968.5
Gamma-Linolenic acid	403706463.5	361965112.3	556892327.4	545306310.4	194006861.4	161720817.7	433486161.1	605105036.5	56375244.4	140624472.6	323343844	194325408.6	1230022171	855994314.1	138904199.4	100161893.3	1454306042	144319196.7	125890445.3	932172173.9	607860320.3	351653258.2	391434423.6	460972382.4	521145774.2	542991280.5	106870723.8	120141001	309604458.9	141593665.4	203231036.1	281358094.8	275901889.7	437170446.9	427012303.3	661893299.4	183193862.4	163432387.6	770434382.4	129467112.9	109840705.3	381888927.8	204645545	1274663384	1054270552	76337432.6	521332549.6	504045524.2	266004443.9	208684974.5	443435491.5	466510603	640605433.9	39377200.7	432478105.6	106501965.5	194411283.2	153513701.6	1075589538	47446479.9	146566278.6	298435143.4	881878089.8	1048314613	20001159.8	287380979.4	483753473.2	556986564.6	69340703.9	594567293.3	119228337.3	100866130.3	452218370.2	507562085.2	292366921.1	237636105.4	564334031.2	147789866	515200743.2	1133340508	491567802.6	198423087.9	482955465.1	1259180758	503885879.5	260508934.9	236259066.9	337097217.7	1247678642	385087951.7	1130252474	140417856.8	372632276.6	154412132.6	456627344.6	439505384.8	446851266.8	236912344.8
Linoleic acid	4222039109	3451624094	5625526959	5295826670	1593416560	2287054312	3743750331	4909295084	811797244.1	2289295881	3650678014	3964892813	8168266229	7439168849	1602998451	908724319.8	8424888656	2143758003	1121005366	8120749744	4999008681	2013551035	3953103136	4794721933	4848371026	4969073139	825275271.5	1561601178	2225336160	1226271010	1409707025	3524325065	2078932784	3609447251	5899886409	5207685701	1495464377	1164664275	5133714330	1338452634	786964189.4	2997181153	1428890089	8468082445	8374661223	932999085.1	4698785421	4448818410	2449810597	2167033992	4133237413	4270350280	4942601454	475867796.7	3661277926	1249784843	1135072827	943567877.7	8112693030	611109729.9	2599152204	4092210549	4790394141	6839017909	248282711	3961832176	3823055175	4598338672	1428505848	5195027064	1103773436	1033131804	4422745540	4705864935	2777659733	2189782125	4262931964	1380132271	4439014397	8932819061	5212687728	1832987177	4734251773	8292264663	5213463347	2535886212	2176681141	3917330680	11033022330	3866962510	7115170789	1169887949	3557113044	1677285490	4698014646	4293912476	4418937686	2530905610
Stearic acid	1027337165	922214406.5	1283566223	1263238972	312822141	899250512.9	639738085	1384597764	674775351.4	524235362.4	746578341	663047831.7	1960190978	1916423844	693809411.1	441801051.1	1615728901	491505272.1	475786069.3	1761292140	723481856.9	590976118.2	1318394331	1049101019	1211955425	1244748854	337473707.7	418055153	404407399.7	585084103.8	356216658.6	855486064.3	536681735.3	751703416.3	1241821840	850302936.7	412599659.5	970226305.8	1159222690	575895561.2	364917140.5	613762964.2	403054756.8	2484645027	1154704448	289022353.1	1117340073	1068191227	549795872.3	700589876.3	1097023505	1041247638	1334542461	290837217.7	961164940.7	550069540.3	274710228.9	268877608.2	1167903330	202572951.6	557970549.3	761039115.6	995115189	1406621164	399692279.3	1216071060	561932824.1	680493635.1	458598083.8	1215959762	418469059.3	381549594.1	1158075064	1297653377	627822337.1	606502795.2	1154792590	404502573.9	671486238.9	1589329413	1532764931	647197180.4	1200746390	1353878421	1085666222	457391151.7	431686678.2	1191626067	2884134540	930056498.9	1644631836	373259640.7	1049435125	598682783.2	1075255868	1014757093	1005314842	744490215.9
All-trans-retinoic acid	0	2296766.4	0	0	1109955.7	1986155.4	1163343.2	1926212.6	6282473	1281697.7	2522160.1	48244808.1	5264693.1	0	3205951.8	4412034.2	4493595.1	33266010.8	17698215.4	0	4385634.7	22993306.8	4136684.1	4607185.6	0	1310219.7	8607767.3	2752807.2	36346281	0	2482553.6	2230524.4	36688400.1	3223854.4	106493567.6	81572894.2	84308149.2	27077419	41531816.4	2426133.1	2236355.7	12765297.7	1765622.2	0	4410996.4	2322582	0	0	384587.8	343507.5	296503.4	0	1635623.3	689961	30483510.3	25972423.7	35659991.8	35194170.4	11385606.5	2983023.4	13365962.8	2027091.5	2659327.3	41790337.1	45086904.1	21283518.6	21787865.4	15011948.5	1193102.3	11745624.9	18963919.2	7356430.1	1077422.6	0	15443859.5	19450626.2	9311050.1	10519181.5	1213461	1579048.3	79292341.2	1303519.7	74863890.7	152277948.8	87692123.2	1603873.6	1666065.5	3336867.6	14381439.6	438868.9	0	94193.7	0	0	382008	0	0	0
N-Acetylneuraminic acid	679259	1207139.6	369174	401648.9	392802.8	237476.9	862272.1	792474.4	4536691.5	830434.1	537903.1	2490102.7	1247745.1	1199999.8	492756.2	641302.8	445668.7	351459.2	497604.8	484232.5	622010.9	596334	439831.7	685291.3	512751.7	414335.3	450899.2	522733	431091.4	365268.7	754676.7	1996909.1	1177429.2	432857.9	946096.7	563445.9	429883.3	583398.1	574604.1	448402.7	445923.8	514025.6	421979.7	507338.2	576869.6	528231.4	514329.6	570060.3	1013983.5	1149087.9	157059.8	177267.9	103260.2	79086.6	557339.8	204875.1	257959.4	454575.8	382749	302267.5	349914.4	1107587.4	544373.3	800384.1	322630.7	845120	2120215.4	1340812.8	891573	1753456.2	409028.4	1002703.5	409871.3	372756.2	910004.4	826746.5	1487148.6	1083160	1321168.7	716744	615950.9	2052620.5	745251.3	439503.5	707952.9	190605.8	836823.9	692528.1	737055.5	0	0	0	319887.3	0	414682.8	800050.4	690889.3	1148235.6
Arachidic acid	0	1805365.5	2731070.9	1307842.9	311608.6	0	375028	369924.3	298250.4	0	0	897064.2	0	260394.1	510414.4	485068.3	384251.5	0	0	544744.1	0	0	817019.6	0	455874.8	0	0	0	874195.1	0	653437.8	0	0	0	0	0	0	0	0	0	0	0	0	1422637.9	0	0	335826.4	0	0	293152	0	249860.1	434419.8	0	1046662.3	790540.1	0	0	0	1256343.9	0	0	446589.4	0	324381.8	0	0	0	0	0	0	0	0	0	0	2149731.3	576359.2	0	95830.8	0	0	0	0	0	0	0	0	0	0	540769.1	1323693.7	566886.5	278882.8	410106.6	581969.7	439411.7	500167.5	0
Docosahexaenoic acid	272057071.8	286938265.9	491860586	473234307.5	75628930.5	188274034.8	278053613.7	934124362.6	21491616	92285734	197800776.9	119230145.9	626216188.5	641453378.9	154023232.6	133493925.6	615755574.5	88319949.8	144839638.1	356818590.1	218256048.6	268850388	473476705.3	240744607.4	507820597.9	552190054.6	154684883	124514009.8	135352534	110331358.9	231016911.3	249003158.6	397887896.1	200903474.7	312029373.4	360714735.6	263828700.4	111613800.1	379159339.3	236425623.1	117777620.1	393728665.7	214057679.6	629720786.3	422006364.4	157770176	538498355.6	499161701.9	288630118	213823016	409321030.3	442500477	141628886.8	66210608.2	152105337.8	91080180.2	69753411.5	45477937.1	438095219.5	22743928.3	127658185.1	92862558.2	458313328.3	459433969.4	85079184.9	379815756.3	221667655.6	364091873.3	209322862.4	542929230	112295646.2	171325998.1	459436011.4	515366610.8	304565130	246745550.7	218128892.2	209051579.2	425197494	568916420.3	618947706.6	330866061.4	513289228.5	860733374	394888211.4	218486531	469655616.1	621114052.4	605880402.6	519729664.4	468120069.6	65545592.6	171133509.6	184422763.8	452689981.6	423573922.6	434149245.8	248357267.5
Leukotriene B4	5121321.3	159704494.6	73470249.3	74145344.5	0	4722309.2	4251869	0	8331365.9	7744633	4664248.1	11410085.7	4523343.8	0	4311838.8	5357303.1	4355741.3	11995269.1	4661871.5	4279820.2	4694021.8	4616614.5	4240000.7	4333490.5	68879993.8	71861315.5	0	4347250.2	4443842.2	0	0	7201908.2	4298735.7	0	8188973.7	4271318.7	4542332.4	0	4342732.8	0	0	0	0	0	0	0	72211912.4	80087017.9	162929655	118658644	55817233.9	54498507.4	0	0	0	0	0	0	1321207.7	0	0	13297325.5	0	0	0	0	0	0	0	0	0	0	61199878.8	76887669.1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	56147656.6	57267697.8	60027586.6	148613842.6
Cholic acid	1927930.2	1239512.5	1581001.6	1505138.6	2950037.8	8588298.8	146783976.1	1946813.5	1510313.8	1044821.3	1765281.3	3872497.2	3098678.5	1223925.8	1248882	3022382	5054381.7	15055247.5	7572558.8	4814379.2	2351558.5	5860185.3	4413500.6	2017155.4	1803381.2	1721953.3	3332373.5	1927211.7	14471231.4	1622392.8	1005473.5	2066858.2	2152868.3	1000083.3	4845747.8	1353681.4	1332470.7	846836.2	1271906.8	5830732	4396852.4	999656	4345606.1	1715432.5	59593023.3	4867160.9	1872884.2	1823361	1242809.1	0	257411.2	228120.2	2632944.1	0	9016347.1	1011176.1	113335003.1	8451602.1	11118795.5	14853779.6	54070113.2	2423507.5	59350742	0	3720591.8	0	4268965.5	3964683.5	1130620.6	2894205.5	0	482361.3	808164.7	716596.9	7544405.1	0	0	919558	7636607.7	0	0	477018.9	0	0	0	0	1110916.7	0	0	569909.3	0	0	0	0	332344.7	418619.8	447643.7	0
Glycocholic acid	2528125.1	1528749.9	9011577.4	7817244	159710218.4	9204981.5	106604172.2	104349691.9	8472834	65727464.2	94495198.9	213522607.7	0	240142503.1	16339162.7	61502333.1	69545061.1	25763996	357915980.6	0	60310547.8	75734606.9	72468304.2	10652575.1	9080278.3	4418909.6	17641960.6	3483819.3	24735703.5	56005829.1	38741509.8	75511858.2	131592778.2	27573009.7	29193038.5	79661948.2	36990396.4	87630368.9	18966301.8	0	74544663.1	19711499.9	22360899.4	0	34564417.8	113212461.3	6742669	6000615.3	1480757.8	11088263.6	15216529.9	15496719.6	75249035	246916106.9	130332358.1	17393550.3	43203523.2	17120713.6	46762224.2	26341468.9	28905568.9	134432384.5	125439271.2	32362144	45348996.5	15248650	405961396.9	172395543.1	85300899.6	226257777.6	39717001.2	75689300.7	16809557.4	15948806.8	153670356.3	27909129.2	13369093.3	36166882.4	154821767.6	9047392.5	13707570.9	10232639.5	5329485.3	7236379.4	7047463.9	70383054.7	15734126.4	13107697.9	7529414.9	36790487.6	9194993.2	9402822.3	0	6834356.5	16751896.9	15827499.5	14558218	12391047.2
Biliverdin	5603784	4379899.1	5995250.7	6368412.1	2495466.6	577230.3	3235097	1870926.6	0	0	3115791	0	2447499.6	2005857.9	2624318.5	4714677.2	7408438.5	176481.4	1964756.8	5368967	3316910.4	2697951.8	1021522.8	2420040	6774798.9	6550758.9	4562553.4	1618281.3	2856429.6	1764652.1	1807268.8	0	1181406.7	3269284.6	0	1379644.6	3338330.3	2155862	1329019.3	3914724.7	4396037.2	3066469.1	2858037.5	2084522	1960938	3011319.8	5134819.6	3710996.7	2583700.5	3938937.1	5758364.1	5544293.3	3666097.3	3548909.7	2558832.3	2197291.1	4375977	2007255.3	1351638.7	3695887.1	3311617.5	0	2037928.7	3237818	4677338.5	0	1748171.9	2686494.1	5747915.3	1255338.5	1302730.6	1657035.3	6016012.4	6918201.1	2077148.1	591452.6	1918819	617867.6	994916.1	443672.1	6677568	4658431.7	3618321.7	3765719.2	2762433.1	1689823.9	1511868.5	2451151.2	3964611.7	4643224	3755378.7	1670892.8	1645424.6	2560807.9	5273723.6	5268197.6	5477488.9	3404588.9
Thyroxine	1119194	1120535.4	700734.3	538497	1245480.8	0	1464606.4	1973252.5	0	0	2789455.2	0	1842480	2612302.4	1369934.2	1138167.1	1467627.5	594598.7	1344329	926103.9	1636592.7	1247144.9	1318440.5	1629413.9	904651.5	1005687.2	740177	1428114.6	1283077.6	956067.3	869993.6	0	2000320.7	1278937.3	304479.7	1580605.1	1615705.2	1939501.9	1047086.9	1267342.5	1580939.2	1453180.3	1413820.9	1363654	1365632.8	1348353.6	759437.6	1078974.5	1173387.2	1368133.4	656815.1	875214.2	1240843.5	796858.3	1834527.7	943001	1120567.8	1119526.1	1011146.4	1022730	1148211.6	596534.7	1764399.5	1420256.6	1675140.4	1604808	2160878.7	1756767.4	2202195.3	1347021	1211789	1533759.4	1159281.4	740862.1	1740411.7	1938493.7	2309710.1	1146198.7	1900715.6	1069854.7	1362572.1	1862843.4	1684664.9	1403579.1	1536858.4	1585289.4	2295111.3	2319692.9	2151094.5	870397.8	888842.7	1014044.9	1005261.9	370449.9	0	826671.3	791889.5	1182963.3
MS_METABOLITE_DATA_END
#METABOLITES
METABOLITES_START
metabolite_name	chemical_ID	InChiKey	quantified m/z	rtimes	MSIcategory	Adduct
Serine	HMDB00187	InChIKey=MTCFGRXMJLQNBG-REOHCLBHSA-N	104.0352	25.6	1	M-H
Glyceric acid	HMDB00139	InChIKey=RBNPOMFGQQGHHO-UWTATZPHSA-N	105.0193	35	1	M-H
Creatinine	HMDB00562	InChIKey=DDRJAANPRJIHGJ-UHFFFAOYSA-N	112.0516	25.2	1	M-H
Mesoxalic acid	HMDB31522	InChIKey=XEEVLJKYYUVTRC-UHFFFAOYSA-N	116.983	17.8	1	M-H
4-Hydroxybenzaldehyde	HMDB11718	InChIKey=RGHHSNMVTDWUBI-UHFFFAOYSA-N	121.0295	47.8	1	M-H
Ureidopropionic acid	HMDB00026	InChIKey=JSJWCHRYRHKBBW-UHFFFAOYSA-N	131.0462	23.4	1	M-H
Aspartic acid	HMDB06483	InChIKey=CKLJMWTZIZZHCS-UWTATZPHSA-N	132.0302	33.6	1	M-H
Hypoxanthine	HMDB00157	InChIKey=FDGQSTZJBFJUBT-UHFFFAOYSA-N	135.0302	35.3	1	M-H
Phenylacetic acid	HMDB00209	InChIKey=WLJVXDMOQOGPHL-UHFFFAOYSA-N	135.0452	39.5	1	M-H
Salicylamide	HMDB15687	InChIKey=SKZKKFZAGNVIMN-UHFFFAOYSA-N	136.0404	45.9	1	M-H
Caprylic acid	HMDB00482	InChIKey=WWZKQHOCKIZLMA-UHFFFAOYSA-N	143.1078	72	1	M-H
Oxoglutaric acid	HMDB00208	InChIKey=KPGXRSRHYNQIFN-UHFFFAOYSA-N	145.0143	32.6	1	M-H
Glutamine	HMDB00641	InChIKey=ZDXPYRJPNDTMRX-VKHMYHEASA-N	145.0619	23.8	1	M-H
trans-Cinnamic acid	HMDB00930	InChIKey=WBYWAXJHAXSJNI-VOTSOKGWSA-N	147.0452	36.5	1	M-H
Methionine	HMDB00696	InChIKey=FFEARJCKVFRZRR-BYPYZUCNSA-N	148.0439	25.2	1	M-H
Xanthine	HMDB00292	InChIKey=LRFVTYWOQMYALW-UHFFFAOYSA-N	151.0262	24.5	1	M-H
Histidine	HMDB00177	InChIKey=HNDVDQJCIGZPNO-YFKPBYRVSA-N	154.0623	27.2	1	M-H
Pelargonic acid	HMDB00847	InChIKey=FBUKVWPVBMHYJY-UHFFFAOYSA-N	157.1234	91.6	1	M-H
Indoleacetaldehyde	HMDB01190	InChIKey=WHOOUMGHGSPMGR-UHFFFAOYSA-N	158.0612	60.1	1	M-H
Aminoadipic acid	HMDB00510	InChIKey=OYIFNHCXNCRBQI-UHFFFAOYSA-N	160.0616	21.1	1	M-H
Phenylalanine	HMDB00159	InChIKey=COLNVLDHVKWLRT-QMMMGPOBSA-N	164.0717	27.4	1	M-H
3-(2-Hydroxyphenyl)propanoic acid	HMDB33752	InChIKey=CJBDUOMQLFKVQC-UHFFFAOYSA-N	165.0557	36.1	1	M-H
Uric acid	HMDB00289	InChIKey=LEHOTFFKMJEONL-UHFFFAOYSA-N	167.0211	21.1	1	M-H
N-Acetylasparagine	HMDB06028	InChIKey=HXFOXFJUNFFYMO-BYPYZUCNSA-N	173.0569	20	1	M-H
Suberic acid	HMDB00893	InChIKey=TYFQFVWCELRYAO-UHFFFAOYSA-N	173.082	31.5	1	M-H
N-Acetyl-L-aspartic acid	HMDB00812	InChIKey=OTCCIMWXFLJLIA-BYPYZUCNSA-N	174.0407	23.8	1	M-H
Indoleacetic acid	HMDB00197	InChIKey=SEOVTRFCIGRIMH-UHFFFAOYSA-N	174.0561	39	1	M-H
Citrulline	HMDB00904	InChIKey=RHGKLRLOHDJJDR-BYPYZUCNSA-N	174.0885	21.8	1	M-H
Hippuric acid	HMDB00714	InChIKey=QIAFMBKCNZACKA-UHFFFAOYSA-N	178.0511	31.5	1	M-H
Tyrosine	HMDB00158	InChIKey=OUYCCCASQSFEME-QMMMGPOBSA-N	180.0667	26.3	1	M-H
N-Acetylglutamic acid	HMDB01138	InChIKey=RFMMMVDNIPUKGG-UHFFFAOYSA-N	188.0565	20.6	1	M-H
5-Hydroxyindoleacetic acid	HMDB00763	InChIKey=DUUGKQCEGZLZNO-UHFFFAOYSA-N	190.051	34.1	1	M-H
Quinic acid	HMDB03072	InChIKey=AAWZDTNXLSGCEK-RKGSPJAZSA-N	191.0562	18.2	1	M-H
12-Hydroxydodecanoic acid	HMDB02059	InChIKey=ZDHCZVWCTKTBRY-UHFFFAOYSA-N	215.1652	80.9	1	M-H
Pantothenic acid	HMDB00210	InChIKey=GHOKWGTUZJEAQD-UHFFFAOYSA-N	218.1031	21.9	1	M-H
Myristic acid	HMDB00806	InChIKey=TUNFSRHWOTWDNC-UHFFFAOYSA-N	227.2016	224.1	1	M-H
Ribose 5-phosphate	HMDB01548	InChIKey=KTVPXOYAKDPRHY-SOOFDHNKSA-N	229.0121	20.5	1	M-H
Cystine	HMDB00192	InChIKey=LEVWYRKDKASIDU-IMJSIDKUSA-N	239.0162	31.3	1	M-H
Uridine	HMDB00296	InChIKey=DRTQHJPVMGBUCF-XVFCMESISA-N	243.0621	24.6	1	M-H
Palmitoleic acid	HMDB03229	InChIKey=SECPZKHBENQXJG-FPLPWBNLSA-N	253.2172	233.8	1	M-H
Palmitic acid	HMDB00220	InChIKey=IPCSVZSSVZVIGE-UHFFFAOYSA-N	255.2328	253.1	1	M-H
Heptadecanoic acid	HMDB02259	InChIKey=KEMQGTRYUADPNZ-UHFFFAOYSA-N	269.2484	270	1	M-H
Gamma-Linolenic acid	HMDB03073	InChIKey=VZCCETWTMQHEPK-QNEBEIHSSA-N	277.2173	223	1	M-H
Linoleic acid	HMDB00673	InChIKey=OYHQOLUKZRVURQ-HZJYTTRNSA-N	279.2329	239.9	1	M-H
Stearic acid	HMDB00827	InChIKey=QIQXTHQIDYTFRH-UHFFFAOYSA-N	283.2641	288.6	1	M-H
All-trans-retinoic acid	HMDB01852	InChIKey=SHGAZHPCJJPHSC-YCNIQYBTSA-N	299.2012	212.5	1	M-H
N-Acetylneuraminic acid	HMDB00230	InChIKey=SQVRNKJHWKZAKO-PFQGKNLYSA-N	308.098	21	1	M-H
Arachidic acid	HMDB02212	InChIKey=VKOBVWXKNCXXDE-UHFFFAOYSA-N	311.2956	298.3	1	M-H
Docosahexaenoic acid	HMDB02183	InChIKey=MBMBGCFOFBJSGT-KUBAVDMBSA-N	327.2328	228.5	1	M-H
Leukotriene B4	HMDB01085	InChIKey=VNYSSYRCGWBHLG-AMOLWHMGSA-N	335.2229	114.7	1	M-H
Cholic acid	HMDB00619	InChIKey=BHQCQFFYRZLCQQ-OELDTZBJSA-N	407.2796	79.1	1	M-H
Glycocholic acid	HMDB00138	InChIKey=RFDAIACWWDREDC-MZMBZMQMSA-N	464.3016	43.5	1	M-H
Biliverdin	HMDB01008	InChIKey=RCNSAJSGRJSBKK-YKSNQIBWSA-N	581.2402	79.4	1	M-H
Thyroxine	HMDB00248	InChIKey=XUIIKFGFIJCVMT-LBPRGKRZSA-N	775.6824	77.3	1	M-H
METABOLITES_END
#END